MH - 8-Hydroxy-2'-Deoxyguanosine UI - D000080242 MN - D3.633.100.759.590.454.240.500 MN - D13.570.230.360.500 MN - D13.570.583.454.240.500 MS - Common oxidized form of deoxyguanosine in which C-8 position of guanine base has a carbonyl group. HN - 2020(1985) BX - 2'-Deoxy-7,8-Dihydro-8-Oxoguanosine BX - 2'-Deoxy-8-Hydroxyguanosine BX - 2'-Deoxy-8-Oxo-7,8-Dihydroguanosine BX - 2'-Deoxy-8-Oxoguanosine BX - 7,8-Dihydro-8-Oxo-2'-Deoxyguanosine BX - 7-Hydro-8-Oxodeoxyguanosine BX - 8-Hydroxydeoxyguanosine BX - 8-Oxo-2'-Deoxyguanosine BX - 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine BX - 8-Oxo-7,8-Dihydrodeoxyguanosine BX - 8-Oxo-7-Hydrodeoxyguanosine BX - 8-Oxo-Deoxyguanosine BX - 8OHdG MH - Accidental Injuries UI - D000081084 MN - C26.40 MS - Injuries resulting from events or circumstances that are unforeseen, unplanned, unanticipated, and without premeditation. HN - 2020 BX - Accident Injury BX - Accidental Injury MH - Actinoplanes UI - D000079584 MN - B3.300.390.400.500.250 MN - B3.510.24.49.500.250 MN - B3.510.415.400.500.250 MN - B3.510.460.410.500.250 MS - A genus of zoospore-forming bacteria in the Micromonosporaceae family that is a source of many clinically important natural products. HN - 2020 MH - Acyclic Monoterpenes UI - D000080462 MN - D2.455.849.575.125 MS - Linear compounds that contain a single monoterpene unit. HN - 2020 MH - Ado-Trastuzumab Emtansine UI - D000080044 MN - D2.540.505.495.500 MN - D4.345.295.500.500 MN - D12.776.124.486.485.114.224.60.875.500 MN - D12.776.124.790.651.114.224.60.875.500 MN - D12.776.377.715.548.114.224.200.875.500 MS - Immunotoxin that consists of humanized monoclonal anti-HER2 antibody TRASTUZUMAB covalently linked to anti-microtubule agent MAYTANSINOID DM1 for treatment of metastatic breast cancer in patients who previously received trastuzumab and a TAXANES, separately or in combination. HN - 2020 (2010) BX - Trastuzumab Emtansine BX - Trastuzumab-DM1 BX - Trastuzumab-DM1 Conjugate MH - Aldehyde Dehydrogenase 1 UI - D000080924 MN - D8.811.682.657.163.249.188 MS - A member of the Aldehyde Dehydrogenase family of enzymes involved in the synthesis of acetate from ethanol. It is also a tumor marker. HN - 2020(1997) BX - Acetaldehyde Dehydrogenase 1 BX - ALDH1 Enzyme MH - Allergoids UI - D000080384 MN - D23.50.63.500 MS - Extracts of allergens, or purified allergens that have been chemically modified to reduce their ability to induce IGE-MEDIATED HYPERSENSITIVITY (allergenicity) while increasing their ability to induce IMMUNE TOLERANCE. HN - 2020 (1980) BX - Formalinized Allergoid BX - Formalized Allergoid BX - High Molecular Weight Allergoid FX - Desensitization, Immunologic MH - Allylbenzene Derivatives UI - D000081248 MN - D2.455.326.271.122.180 MN - D2.455.426.559.389.12 MS - Compounds that include a single 1-phenyl-2-propene moiety in their structure. HN - 2020 BX - 1-Methyl-1-phenylethylene Derivatives BX - 1-Phenyl-2-propene Derivatives BX - 2-Propenylbenzene Derivatives BX - 3-Ethenylmethylbenzene Derivatives BX - Allylbenzenes BX - Vinyl Toluene Derivatives FX - Stilbenes MH - Alouatta caraya UI - D000080532 MN - B1.50.150.900.649.313.988.400.600.75.50.75.500 MS - A species of the genus ALOUATTA, family ATELIDAE, inhabiting the forests of South America. Although sometimes known as black howler only adult males have black hair and adult females and juveniles are gold in color. Closely related A. pigra in Central America and A. nigerrima in the Amazon are also called black howlers. AN - NIM when experimental animal; diseases: coordinate with MONKEY DISEASES HN - 2020 BX - Black Howler Monkey, Paraguayan BX - Black-and-Gold Howler Monkeys BX - Mono Aullador BX - Paraguayan Black Howler Monkey MH - Ambient Intelligence UI - D000080910 MN - L1.224.900.910.500 MS - An emerging paradigm in which people are empowered through intelligent (digital) tools embedded in the surrounding environment. These tools proactively support human existence by being sensitive, adaptive, and responsive to the needs, habits, gestures, and emotions of individuals. HN - 2020 BX - Ambient Assisted Living BX - Ambient-Assisted Living MH - Animal Proteins, Dietary UI - D000080224 MN - D12.776.256.159 MN - G7.203.300.428.159 MN - J2.500.428.159 MS - DIETARY PROTEINS derived from ANIMALS. AN - general or unspecified; prefer specifics HN - 2020 MH - Anomalous Left Coronary Artery UI - D000080038 MN - C14.240.400.210.125 MN - C14.280.400.210.125 MN - C16.131.240.400.210.125 MS - Malformations of left CORONARY ARTERY where it is connected to the PULMONARY ARTERY instead of the AORTA. HN - 2020 MH - Araucaria UI - D000080057 MN - B1.650.940.800.575.912.625.500.500 MS - A genus of evergreen conifer of the family Araucariaceae, order Pinales, that includes the monkey puzzle (Araucaria Araucana). HN - 2020 BX - Araucaria augustifolia BX - Brazilian Pine MH - Araucaria araucana UI - D000080059 MN - B1.650.940.800.575.912.625.500.500.250 MS - An evergreen tree commonly known as the monkey-puzzle tree. It grows to 1-1.5 m in diameter and 30-40 m in height, and is native to central and southern Chile, and western Argentina. Araucaria araucana is the hardiest among the conifers, and due to its longevity, is often described as a living fossil. HN - 2020 MH - Araucariaceae UI - D000080056 MN - B1.650.940.800.575.912.625.500 MS - A family of dioecious or monoecious evergreen trees belonging to the order Pinales, subclass Pinidaes, with spirally arranged, narrow or broad leaves often with parallel veins. HN - 2020 MH - Artificially Sweetened Beverages UI - D000081229 MN - G7.203.100.200 MN - J2.200.200 MS - Beverages sweetened with SWEETENING AGENTS that are synthetic or artificial as opposed to naturally-occurring. Examples of sweetening agents include ASPARTAME, sucralose, and saccharin. HN - 2020 BX - Diet Beverages BX - Diet Drinks MH - Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome UI - D000080445 MN - C8.127.108.688 MN - C8.381.495.108.500 MN - C8.381.495.389.250 MN - C8.674.95.688 MN - C20.543.103 MS - Syndrome with clinical features of both ASTHMA and COPD. HN - 2020 BX - Asthma-COPD Overlap Syndrome MH - Ateles geoffroyi UI - D000080583 MN - B1.50.150.900.649.313.988.400.600.75.75.500 MS - A species in the genus ATELES, subfamily ATELINAE, comprising several Mesoamerican spider monkeys including Geoffroy's spider monkey (Ateles geoffroyi geoffroyi). Sometimes referred to as Central American spider monkey, it inhibits rainforest from Mexico to Colombia. AN - NIM when experimental animal; diseases: coordinate with MONKEY DISEASES HN - 2020 BX - Ateles geoffroyi frontatus BX - Ateles geoffroyi ornatus BX - Ateles geoffroyi panamensis BX - Ateles geoffroyi rufiventris BX - Ateles geoffroyi vellerosus BX - Ateles geoffroyi yucatanesis BX - Central American Spider Monkey BX - Geoffroy's Spider Monkey MH - Atomic Bomb Survivors UI - D000080483 MN - M1.860.325 MS - Persons who survived exposure to RADIATION due to ATOMIC BOMBS. HN - 2020 BX - Atomic Bomb-Affected People BX - Hibakusha FX - Radiation Injuries FX - Radioactive Fallout MH - Augmented Reality UI - D000081411 MN - L1.224.160.125 MN - L1.296.55 MS - Technology in which images of virtual objects and/or other digital information are superimposed over the real time view of the physical objects providing a composite view with guides for carrying out a task with or on the physical objects. HN - 2020 BX - Mixed Reality FX - Computer-Assisted Instruction FX - Surgery, Computer-Assisted MH - Autoimmune Pancreatitis UI - D000081012 MN - C6.689.750.830.500 MN - C20.111.296 MS - Chronic pancreatitis associated with autoimmune diseases. HN - 2020 BX - Idiopathic Duct-centric Pancreatitis BX - IgG4-related Pancreatitis BX - Type 1 AIP BX - Type 1 Autoimmune Pancreatitis BX - Type 2 AIP BX - Type 2 Autoimmune Pancreatitis FX - Immunoglobulin G4-Related Disease MH - Autophagic Cell Death UI - D000080549 MN - G4.11.500 MN - G4.146.954.53 MS - A major activation of the autophagic pathway, characterized by massive accumulation of AUTOPHAGOSOMES and CELL DEATH. HN - 2020; use Autophagy 2006-2019 BX - Autophagy-Dependent Cell Death MH - Avoidant Restrictive Food Intake Disorder UI - D000080146 MN - F3.400.157 MS - An eating or feeding disturbance (e.g., apparent lack of interest in eating or food; avoidance based on the sensory characteristics of food; concern about aversive consequences of eating) as manifested by persistent failure to meet appropriate nutritional and/or energy needs associated with one (or more) of the following: significant weight loss (or failure to achieve expected weight gain or faltering growth in children); significant nutritional deficiency; dependence on enteral feeding or oral nutritional supplements; or marked interference with psychosocial functioning. (from DSM-V) HN - 2020 BX - ARFID BX - Food Neophobia MH - B-Cell Lymphoma 3 Protein UI - D000081242 MN - D12.776.624.664.700.165 MN - D12.776.930.714 MS - A member of the I kappa B family, B-cell lymphoma 3-encoded (bcl-3) protein is involved in the regulation of TRANSCRIPTIONAL ACTIVATION of NF-KAPPA B target genes. HN - 2020 BX - BCL-3 Protein BX - BCL3 Protein BX - c-bcl-3 Protein BX - Protein c-bcl-3 BX - Proto-Oncogene Protein bcl-3 BX - Proto-Oncogene Proteins c-bcl-3 MH - Bacterial Outer Membrane UI - D000080943 MN - A11.284.149.83 MN - A20.484 MS - The outermost cell envelope of GRAM-NEGATIVE BACTERIA composed of PHOSPHOLIPIDS; LIPOPOLYSACCHARIDES (LPS), and BACTERIAL OUTER MEMBRANE PROTEINS. The bacterial outer membrane LPS demonstrates cytotoxicity (see LIPID A and BACTERIAL O ANTIGEN). HN - 2020 MH - Bicyclic Monoterpenes UI - D000081008 MN - D2.455.426.100.80.50 MN - D2.455.849.575.141 MS - Monoterpenes containing two ring structures that are joined either by bridgehead carbon atoms or fused ring structure. HN - 2020 BX - Camphene Derivatives BX - Camphenes BX - Carane Derivatives BX - Caranes BX - Pinane Derivatives BX - Pinanes BX - Thujane Derivatives BX - Thujanes MH - Bioaccumulation UI - D000081482 MN - G3.15.500.187 MN - G3.787.24.500.187 MN - G7.690.725.15.500.187 MS - An increase in the concentration of an exogenous substance in the tissues of organisms higher than surrounding ENVIRONMENT. Accumulation of such XENOBIOTICS at successively higher levels up the FOOD CHAIN is called biomagnification. Bioaccumulation of toxic chemicals (e.g., Lead and DDT) may result in CHEMICALLY-INDUCED DISORDERS. HN - 2020 BX - Bio Accumulation BX - Bio Amplification BX - Bio Concentration BX - Bio Magnification BX - Bio-accumulation BX - Bio-amplification BX - Bio-concentration BX - Bio-magnification BX - Bioamplification BX - Bioconcentration BX - Biomagnification FX - Chemically-Induced Disorders MH - Biological Monitoring UI - D000079687 MN - N6.850.460.350.80.125 MN - N6.850.780.375.175 MS - Monitoring of the level of toxins, chemical pollutants, microbial contaminants, or other harmful substances in the bodies of living organisms, by DIAGNOSTIC IMAGING or by analyzing BLOOD; URINE; BREAST MILK; SALIVA, etc. HN - 2020; use ENVIRONMENTAL MONITORING 1985-2019 MH - Biosolids UI - D000080803 MN - D20.944.730.500 MS - Wastewater SLUDGE treated by processes such as COMPOSTING, anaerobic digestion, aerobic digestion, alkaline treatment, and PASTEURIZATION to remove HAZARDOUS CHEMICALS and pathogens. HN - 2020 MH - Birdshot Chorioretinopathy UI - D000080365 MN - C11.768.773.348.500 MN - C11.941.160.478.400.500 MN - C11.941.879.780.900.300.318.500 MN - C11.941.879.780.900.650.250 MN - C20.111.303 MS - A form of chorioretinitis characterized by multiple small, cream-colored LESIONS, symmetrically scattered mainly around the OPTIC DISK. These lesions are the most distinctive sign and often appear at the level of the RETINAL PIGMENT EPITHELIUM but, on occasion, suggest an even deeper infiltration and may ultimately lead to visual loss. An association with HLA-A29 antigen (see HLA-A ANTIGENS) has been observed in nearly all patients. HN - 2020 BX - Birdshot Chorioretinitis BX - Birdshot Retinochoroiditis BX - Birdshot Retinochoroidopathy MH - Blockchain UI - D000081186 MN - L1.224.134.250 MN - N4.452.910.200.250 MS - Decentralized transaction and data management technology providing security, anonymity and data integrity without any third party control of transactions. Related research is focused on improving aspects regarding privacy and security. (From PLoS One. 2016 Oct 3;11(10):e0163477) HN - 2020 BX - Block Chain MH - Body Dissatisfaction UI - D000079182 MN - F1.752.747.792.110.500 MS - Person’s negative thoughts about his or her own body. This includes judgements about size and shape, muscle tone and generally involves a discrepancy between one's own body type and an ideal body type. (Grogan, 2008) HN - 2020 MH - Body Integrity Identity Disorder UI - D000081042 MN - F3.875.225 MS - Condition in which individuals desire the amputation of one or more healthy limbs or who desire a paralysis. HN - 2020 BX - Amputee Identity Disorder BX - Apotemnophilia BX - BIID BX - Body Integrity Disorder BX - Foreign Limb Syndrome BX - Xenomelia MH - Bone Marrow Failure Disorders UI - D000080983 MN - C15.378.190.223 MS - Inherited or acquired diseases characterized by insufficient and/or dysplastic blood cells. HN - 2020(2011) BX - Bone Marrow Failure BX - Bone Marrow Failure Syndromes MH - Brain Regeneration UI - D000080843 MN - G16.762.309 HN - 2020 BX - Endogenous Regeneration of Brain MH - Brentuximab Vedotin UI - D000079963 MN - D12.644.456.217 MN - D12.776.124.486.485.114.224.60.438 MN - D12.776.124.790.651.114.224.60.469 MN - D12.776.377.715.548.114.224.200.469 MS - Immunoconjugate that consists of the chimeric monoclonal anti - CD30 ANTIGEN antibody cAC-10 conjugated to monomethyl auristatin E. It is used for the treatment of LYMPHOMA. HN - 2020 (2010) MH - Broadly Neutralizing Antibodies UI - D000080908 MN - D12.776.124.486.485.114.244.500 MN - D12.776.124.790.651.114.244.500 MN - D12.776.377.715.548.114.244.500 MS - Neutralizing antibodies that reduce or abolish some biological activity of a soluble antigen or infectious agent (e.g., HIV) by targeting several epitopes. HN - 2020 BX - bnAbs BX - Broad Neutralizing Antibodies BX - Broad Spectrum Antibodies BX - Cross-Neutralizing Antibodies MH - Calicheamicins UI - D000080084 MN - D2.455.326.271.244.250 MN - D2.455.326.397.680.500.500.250 MN - D9.408.51.247 MS - Enediyne aminoglycosides derived from the bacterium MICROMONOSPORA ECHINOSPORA that are used as antineoplastic antibiotics. They bind to DNA in both healthy and tumor cells, resulting in strand scission and cell death. HN - 2020 BX - Calicheamicin MH - Callicebus UI - D000080602 MN - B1.50.150.900.649.313.988.400.600.575.500 MS - A genus of the subfamily CALLICEBINAE, family PITHECIIDAE, generally comprising of five species: C. barbarabrownae; C. coimbrai; C. melanochir; C. nigrifrons; C. personatus. Titi monkeys inhibit lower levels of the forest in South America. AN - NIM when experimental animal; diseases: coordinate with MONKEY DISEASES HN - 2020; use PITHECIIDAE 2007-2019 BX - Titi Monkeys MH - Cardio Ankle Vascular Index UI - D000080308 MN - E1.370.370.680.500 MS - An index of ARTERIAL STIFFNESS obtained from PULSE WAVE VELOCITY measurements between the heart and the ankle. HN - 2020 MH - Carotid-Femoral Pulse Wave Velocity UI - D000080909 MN - E1.370.370.680.750 MS - The transit time of an AORTIC PRESSURE wave between the COMMON CAROTID ARTERY and the COMMON FEMORAL ARTERY. It is a standard measure of ARTERIAL STIFFNESS. HN - 2020 BX - Carotid-Femoral Pulse Wave Velocities MH - Cebus capucinus UI - D000080526 MN - B1.50.150.900.649.313.988.400.600.150.170.120.500 MS - A species of the genus CEBUS, family CEBIDAE, consisting of capuchin monkeys with white markings over most of frontal areas of the face, chest and upper arms. AN - NIM when experimental animal; diseases: coordinate with MONKEY DISEASES HN - 2020 BX - C. capucinus BX - Cebus capucinus imitator BX - Colombian White-Faced Capuchin BX - White-Faced Capuchin BX - White-Faced Capuchin Monkeys BX - White-Throated Capuchin MH - Cell Encapsulation UI - D000079585 MN - E5.481.500.311.500.500 MS - The encapsulation of cells into semi-permeable microcapsules or MICROSPHERES that permits protection of encapsulated cells and allows passage of essential nutrients and release of a therapeutic product (e.g. INSULIN). HN - 2020 BX - Cellular Encapsulation FX - Cells, Immobilized MH - Cell Line Authentication UI - D000081163 MN - E5.200.500.265.250 MN - E5.242.223.250 MS - Techniques used to characterize and confirm the identity of a CELL LINE. Characterization involves authentication to verify that it matches the original description of the cells and ensures that they are not cross-contaminated with another cell line. This is done to avoid attributing data incorrectly to the wrong cell line. HN - 2020 BX - Cell Line Misidentification BX - Cell-Line Authentication BX - Cell-Line Identification MH - Cerebellar Golgi Cells UI - D000080906 MN - A8.186.211.132.810.428.200.212.150 MN - A8.675.358.200 MN - A11.671.358.131 MS - Inhibitory interneurons embedded in the granular layer of the CEREBELLAR CORTEX. HN - 2020 BX - Golgi Cells of the Cerebellum MH - Chaperone-Mediated Autophagy UI - D000080642 MN - G4.11.625 MS - A selective type of autophagy in which a specific set of cytosolic proteins are moved across the membrane of the LYSOSOMES by protein translocation, rather than by invagination of the lysosomal membrane. The proteins that will be degraded by chaperone-mediated autophagy (CMA) contain a CMA-targeting motif that, when exposed, is recognized by the cytosolic chaperone HSPA8 (aka Hsc70) and cochaperones which deliver the protein to LAMP2A monomers on the lysosome cell surface for translocation via the LAMP2A translocation complex. CMA is distinguished from CHAPERONE-ASSISTED-SELECTIVE AUTOPHAGY - a type of selective MACROAUTOPHAGY. HN - 2020 MH - Cheminformatics UI - D000080911 MN - H1.181.169 MN - L1.313.62 MS - The use of computational and data retrieval techniques in understanding problems of chemistry. Cheminformatics strategies are useful in high throughput drug discovery. HN - 2020 BX - Chemoinformatics MH - Choroidal Effusions UI - D000080324 MN - C11.250.105 MN - C11.941.160.241 MS - Finding of fluid accumulation between the CHOROID and the SCLERA. HN - 2020 BX - Choroidal Detachment BX - Ciliochoroidal Detachment BX - Ciliochoroidal Effusions BX - Suprachoroidal Space MH - Chromatin Immunoprecipitation Sequencing UI - D000081204 MN - E5.393.170.500 MN - E5.393.760.319.250 MN - E5.393.760.700.75 MN - E5.478.605.160.500 MS - A technique for identifying the BINDING SITES on nucleic acid sequences that are associated with binding proteins. HN - 2020 BX - Assay for Transposase-Accessible Chromatin Using Sequencing BX - ATAC-Seq BX - ChIA-PET BX - ChIP Sequencing BX - ChIP-Chip BX - ChIP-Exo BX - ChIP-Exonuclease BX - ChIP-PET BX - ChIP-Seq BX - Chromatin Immuno-Precipitation Paired-End Tag BX - Chromatin Immuno-precipitation Sequencing BX - Chromatin Immunoprecipitation Paired-End Tag BX - Chromatin Immunoprecipitation Sequencing-Chip BX - CLIP-Seq BX - Cross-Linking and Immunoprecipitation Followed by Deep Sequencing BX - High-Throughput Sequencing of RNA Isolated by Crosslinking Immunoprecipitation BX - HITS-CLIP MH - Chronic Disease Indicators UI - D000079662 MN - E5.318.308.980.438.475.411 MN - N5.715.360.300.800.438.375.91 MN - N6.850.520.308.980.438.475.23 MS - A set of surveillance indicators of disease developed by consensus among the CDC, the Council of State and Territorial Epidemiologists, and the National Association of Chronic Disease Directors. It enables public health professionals and policymakers to retrieve uniformly defined state and selected metropolitan-level data for CHRONIC DISEASES and RISK FACTORS that impact public health.(https://www.cdc.gov/socialdeterminants/data/index.htm) HN - 2020 BX - Chronic Disease Surveillance MH - Chronic Urticaria UI - D000080223 MN - C17.800.862.945.533 MN - C20.543.480.904.533 MS - Wheals and/or angioedema presented with daily symptoms lasting for more than 6 weeks. It may be classified into chronic spontaneous and chronic inducible urticaria depending on whether a specific trigger can be linked to the development of vascular reaction. HN - 2020 BX - Autoimmune Urticaria BX - Chronic Autoimmune Urticaria BX - Chronic Idiopathic Urticaria BX - Chronic Inducible Urticaria BX - Chronic Spontaneous Urticaria BX - CIndU BX - Idiopathic Chronic Urticaria MH - Citizen Science UI - D000080029 MN - H1.770.644.193.500 MN - N3.540.245.360.150 MS - Voluntary public participation in the scientific process, addressing real-world problems in ways that may include formulating research questions, conducting scientific experiments, collecting and analyzing data, interpreting results, making new discoveries, developing technologies and applications, for solving complex problems. (From https://www.citizenscience.gov/) HN - 2020 FX - Decision Making MH - Claustrum UI - D000079482 MN - A8.186.211.200.885.287.249.320 MS - A gray matter lamina located underneath the inner NEOCORTEX lateral to the PUTAMEN and medial to the INSULAR CORTEX. It is considered to be a part of the basal ganglia. Extensive claustral projections exist to most cortices and subcortical structures including the AMYGDALA, the CAUDATE NUCLEUS, the HIPPOCAMPUS and the THALAMUS. HN - 2020; use BASAL GANGLIA (1978-2019) MH - Clinical Decision Rules UI - D000081415 MN - E5.245.190 MN - L1.313.500.750.190.190 MS - Scores or algorithms that correlate with clinically significant findings and that are used to predict an outcome, or suggest a diagnostic or therapeutic action. HN - 2020 FX - Practice Guidelines as Topic MH - Codon Usage UI - D000081183 MN - G5.360.335.355.113 MS - The frequency of occurrence, in a specific organism's DNA sequence, of one of several potential synonymous codons that code for a particular amino acid. Frequently, there is a nonrandom pattern (bias) in the usage of a particular codon or codons over other synonymous codons. HN - 2020 BX - Codon Bias BX - Codon Preference BX - Codon Usage Bias BX - Codon Usage Pattern BX - Synonymous Codon Usage MH - Community-Based Health Insurance UI - D000080051 MN - N3.219.521.576.343.108 MS - Low-cost HEALTH INSURANCE in which community, cooperative, mutual, and/or self-help resources are pooled to mitigate health risks and cover health care services in full or in part. HN - 2020 BX - Community Health Insurance BX - Community-Based Health Financing BX - Health Micro Insurance BX - Micro-Health Insurance BX - Mutual Health Insurance MH - Computational Chemistry UI - D000080486 MN - H1.181.590 MS - A branch of chemistry that utilizes computers as well as principles of chemistry and mathematics to generate data and solve problems related to the properties, structures, and reactions of molecules and materials. HN - 2020 FX - Computational Biology MH - Congenital Bone Marrow Failure Syndromes UI - D000080984 MN - C15.378.190.223.500 MN - C16.614.183 MS - Inherited syndromes characterized by deficiency or absence of various blood cells due to mutations that affect HEMATOPOIETIC STEM CELLS development and proliferation. HN - 2020 BX - Bone Marrow Failure Syndromes, Congenital BX - Bone Marrow Failure Syndromes, Inherited BX - CBMFS BX - IBMFS BX - Inherited BMF Syndromes BX - Inherited Bone Marrow Failure Syndromes MH - Congenitally Corrected Transposition of the Great Arteries UI - D000080041 MN - C14.240.400.915.150 MN - C14.280.400.915.150 MN - C16.131.240.400.915.150 MS - A rare heart defect that occurs when the HEART VENTRICLES and attached valves, the MITRAL VALVE and the TRICUSPID VALVE are reversed so that the AORTA and the PULMONARY ARTERY are connected to the wrong ventricle. Although the heart valves and the two great arteries, the PULMONARY ARTERY and the AORTA are transposed, the blood flows to the correct place because the ventricles are also reversed and therefore corrects the transposition. It often occurs with other structural heart abnormalities. HN - 2020(2010) BX - Congenitally Corrected Transposition BX - Congenitally Corrected Transposition of the Great Vessels MH - Continuous Renal Replacement Therapy UI - D000079664 MN - E2.870.150 MN - E4.292.438 MS - Procedures with continuous blood purification (e.g., dialysis, filtration or perfusion) via vascular access designed to mimic kidney function in kidney diseases (e.g., ACUTE RENAL FAILURE and poisoning). HN - 2020; for HEMOFILTRATION, CONTINUOUS ARTERIOVENOUS use HEMOFILTRATION 1988-2019 BX - CAVHD BX - Continuous Arterio-Venous Ultrafiltration BX - Continuous Renal Replacement Procedure BX - Continuous RRT BX - Continuous Veno-Venous Hemodiafiltration BX - Continuous Veno-Venous Hemodialysis BX - Continuous Veno-Venous Hemofiltration BX - Continuous Venovenous Hemodiafiltration BX - Continuous Venovenous Hemodialysis BX - Continuous Venovenous Hemofiltration BX - CRRT Technique BX - CVVH Technique BX - CVVHD BX - CVVHDF BX - Hemofiltration, Continuous Arteriovenous BX - SCUF Technique BX - Slow Continuous Ultrafiltration MH - Contraceptive Agents, Hormonal UI - D000080066 MN - D27.505.696.875.360.360 MN - D27.505.954.705.360.360 MS - Contraceptive agents that act on the ENDOCRINE SYSTEM. HN - 2020 BX - Contraceptive Agents, Female Hormonal BX - Contraceptive Agents, Male Hormonal BX - Hormonal Contraceptive Agents FX - Hormonal Contraception MH - Copper Transport Proteins UI - D000079922 MN - D12.776.157.530.450.250.578 MN - D12.776.543.585.450.250.578 MS - Membrane proteins that facilitate the transport of copper cations across biological membranes. HN - 2020 BX - Copper Transporters MH - Copper Transporter 1 UI - D000079923 MN - D12.776.157.530.450.250.578.875.500 MN - D12.776.157.530.937.640.500 MN - D12.776.543.585.450.250.578.875.500 MN - D12.776.543.585.937.762.500 MS - A high-affinity, saturable copper transporter of the PLASMA MEMBRANE that functions in the absorption of dietary copper. HN - 2020 (1994) BX - Copper Influx Transporter BX - Copper Transport Protein 1 BX - COPT1 Protein BX - SLC31A1 Protein MH - Cricket Sport UI - D000080304 MN - I3.450.642.845.255 MS - A competitive sport played with a bat and ball between two teams of eleven players. HN - 2020 MH - CSK Tyrosine-Protein Kinase UI - D000081247 MN - D8.811.913.696.620.682.725.800.158 MS - Protein tyrosine kinases that phosphorylate tyrosine residues located in the C-terminal tails of SRC-FAMILY KINASES. HN - 2020 BX - c-src Kinase BX - c-src Tyrosine Kinase BX - C-Terminal Src Kinase BX - Carboxy-Terminal Src Kinase BX - Protein Tyrosine Kinase p50(csk) BX - Protein-Tyrosine Kinase c-src BX - Protein-Tyrosine Kinase C-Terminal Src Kinase BX - Tyrosine Protein Kinase p50csk BX - Tyrosine-Protein Kinase CSK MH - Cupping Therapy UI - D000079742 MN - E2.190.233 MS - A traditional practice, most notably in traditional medicine, which involves placing cups on the skin to create suction believed to help increase blood flow and promote healing associated with chronic neck and low back pain in the short term (From National Center for Complementary and Integrative Health, https://nccih.nih.gov/news/cupping (Accessed 11/5/2018)). HN - 2020 BX - Cupping Treatment MH - Cyclams UI - D000080027 MN - D2.92.782.229 MN - D4.345.77 MS - Compounds made of fourteen-member tetraamine macrocycles which bind strongly to a wide range of metal ions. HN - 2020; use LACTAMS, MACROCYCLIC 2003-2019 BX - 1,4,8,11-Tetraazacyclotetradecane BX - Bicyclams BX - Cyclam Derivatives BX - Cyclens BX - Tetraazamacrocycles MH - Cyclodialysis Clefts UI - D000080322 MN - C11.250.105.250 MN - C11.941.160.241.250 MS - Finding of a separation of the CILIARY BODY in the SCLERAL SPUR region, creating aqueous outflow from the ANTERIOR CHAMBER into suprachoroidal space between the CHOROID and the SCLERA. Persistent cyclodialysis clefts may be associated with OCULAR HYPOTENSION and OPTIC DISC EDEMA. HN - 2020 BX - Persistent Cyclodialysis Clefts BX - Traumatic Cyclodialysis MH - Cyclohexane Monoterpenes UI - D000081005 MN - D2.455.426.392.368.367.211 MN - D2.455.849.575.157 MS - Monoterpenes that include a cyclohexane ring in their structure. HN - 2020 MH - Cyclopentane Monoterpenes UI - D000081004 MN - D2.455.426.392.368.450.675 MN - D2.455.849.575.188 MS - Monoterpenes that include a cyclopentane ring in their structure. HN - 2020 MH - Cyclophilin D UI - D000081406 MN - D8.811.399.325.500.400.300.875 MS - A member of the cyclophilins family of isomerases which plays a role in the regulation of the permeability transition pore in mitochondria. HN - 2020 BX - Cyclophilin 40 BX - Cyclophilin-40 BX - Peptidyl-Prolyl Isomerase F BX - PPIF Cyclophilin MH - Cymenes UI - D000081007 MN - D2.455.426.559.389.310 MN - D2.455.849.575.219 MS - A subclass of monoterpenes that contain a single benzene ring structure with an isopropyl group and one or more methyl groups. HN - 2020 BX - Benzenoid Menthanes MH - Cytokine Release Syndrome UI - D000080424 MN - C23.550.470.790.250 MN - C23.550.835.900.356 MS - A systemic inflammatory response triggered by a variety of factors used in IMMUNOTHERAPY. It is characterized by marked elevations of various inflammatory CYTOKINES and by the following associated conditions: DYSPNEA; FEVER; HEADACHE; HYPOTENSION; NAUSEA; RASH; TACHYCARDIA and/or HYPOXIA. HN - 2020 MH - Data Management UI - D000079803 MN - L1.399.375 MN - L1.453.233 MN - L1.470.563 MS - Processes that include acquiring, validating, storing, protecting, and processing data to ensure accessibility, reliability, and timeliness for users. AN - coordinate with specific type of data HN - 2020 BX - Data Administration FX - Big Data FX - Database Management Systems MH - Decision Making, Shared UI - D000080536 MN - F2.463.785.810.250 MN - I3.743.500 MS - Collaborative process of reaching a decision. HN - 2020 MH - Demoralization UI - D000079224 MN - F1.829.477.500 MS - Weakening of hope, courage, or confidence. HN - 2020 MH - Diabulimia UI - D000080887 MN - F3.400.375 MS - Eating disorder occurring typically in patients with Diabetes Mellitus, Type 1 who restrict insulin intake in order to lost weight. HN - 2020 BX - Eating Disorder Diabetes Mellitus Type 1 MH - Diffuse Intrinsic Pontine Glioma UI - D000080443 MN - C4.557.465.625.600.380.185 MN - C4.557.470.670.380.185 MN - C4.557.580.625.600.380.185 MN - C4.588.614.250.195.411.100.500 MN - C10.228.140.211.500.100.500 MN - C10.551.240.250.400.200.500 MS - A rare, aggressive brain tumor that forms in the GLIAL CELLS in the PONS. AN - coordinate with BRAIN STEM NEOPLASMS HN - 2020 BX - DIPG Brain Tumors BX - DIPG, Diffuse Intrinsic Pontine Glioma MH - Dihydrostilbenoids UI - D000081014 MN - D2.455.426.559.389.140.308.500 MN - D2.455.426.559.389.150.700.288 MS - Organic compounds characterized by the functional group 1,2-dihydrostilbene. HN - 2020 BX - Dihydrostilbene Derivatives BX - Dihydrostilbenes MH - Disruptive Technology UI - D000079203 MN - J1.897.200 MS - A process by which a product or service takes root initially in simple applications at the bottom of a market and then relentlessly moves up market, eventually displacing established competitors. (http://www.claytonchristensen.com/key-concepts) HN - 2020 MH - Drug Collateral Sensitivity UI - D000081164 MN - G7.690.773.968.352 MS - Increase in sensitivity of an organism, disease, or tissue to one drug that develops following the loss of sensitivity (i.e. resistance) to another drug. HN - 2020 BX - Antibiotic Collateral Sensitivity BX - Collateral Sensitivity MH - Dry Needling UI - D000079245 MN - E2.190.292 MN - E2.779.413 MS - Intervention that uses a thin filiform needle to penetrate the skin and stimulate underlying myofascial trigger points, muscular, and connective tissues for the management of neuromusculoskeletal pain and movement impairments. HN - 2020 MH - Dual Anti-Platelet Therapy UI - D000080903 MN - E2.319.310.537 MS - Treatment with a combination of two types of antiplatelet agents to prevent blood clotting - usually ASPIRIN and another of the PLATELET AGGREGATION INHIBITORS. HN - 2020 FX - Platelet Aggregation Inhibitors MH - Duocarmycins UI - D000080890 MN - D3.383.129.578.275 MN - D3.633.100.473.278 MS - A group of pyrroloindole compounds often with additional spirocyclic unit(s) and their analogs originally isolated from STREPTOMYCES. They bind DNA minor grooves with adenine-N3 alkylation activity. HN - 2020 BX - Duocarmycin MH - Duration of Therapy UI - D000081206 MN - E2.760.287 MN - N2.421.585.287 MS - Planned or actual duration of various treatments or preventive measures. HN - 2020 BX - Duration of Treatment MH - E-Cigarette Vapor UI - D000079522 MN - D26.255.165.55.173 MS - Complex mixture of vaporized chemicals emitted during SMOKING of E-CIGARETTES. AN - coordinate with AIR POLLUTION if pertinent HN - 2020 FX - Vaping MH - Early Warning Score UI - D000080162 MN - E5.318.308.980.438.475.456.500.375 MN - N5.715.360.300.800.438.375.364.500.375 MN - N6.850.520.308.980.438.475.364.500.375 MS - Tool for bedside evaluation based on five physiological parameters: SYSTOLIC PRESSURE, PULSE, RESPIRATORY RATE, BODY TEMPERATURE and AVPU (alert, voice, pain, unresponsive) score. HN - 2020 MH - Edible Films UI - D000080122 MN - J1.576.423.850.600.200 MN - J1.576.761.350 MS - Packaging materials that can be directly consumed. They provide barrier and protection, while enhancing quality and safety of food products. (Bourtoom, 2008). HN - 2020 BX - Edible Coating BX - Edible Food Packaging Materials BX - Edible Packaging MH - Edible Insects UI - D000080702 MN - B1.50.500.131.617.276 MN - G7.203.300.463 MN - J2.500.463 MS - Organisms of the INSECTA class that are used as food or are suitable as a nutritional source, especially by humans. HN - 2020 BX - Insects As Food MH - Emotional Regulation UI - D000080103 MN - F1.145.813.595.500 MN - F1.470.311 MS - The manifestation of an emotional response by which individuals influence the intensity, duration, valence, or manifestation of their response. Emotion regulation either precedes (avoidance, interpretation) or follows an emotion (suppression, reappraisal). Emotion regulation is distinct from coping (focuses primarily on decreasing a negative emotional experience), and can include increasing or decreasing both positive and negative emotions consciously or unconsciously. HN - 2020 BX - Emotion Regulation BX - Emotion Self-Regulation BX - Emotional Self-Regulation MH - Empowerment UI - D000079102 MN - F1.145.813.195 MN - F1.658.780.500 MS - Process of increasing the capacity of individuals or groups to make choices and to transform those choices into desired actions as deigned by the individuals or groups. HN - 2020 MH - Enhanced Recovery After Surgery UI - D000080482 MN - E4.604.125 MS - A protocol of components related to preadmission, preoperative, intraoperative, and postoperative care. The protocol is implemented with the goal of improving patient recovery, facilitating earlier discharge from the hospital, and potentially reducing health care costs without increasing complications or hospital readmissions. The protocol components may contribute to minimizing, and/or improving the response to, physiological stress associated with surgery. HN - 2020 BX - Enhanced Postsurgical Recovery MH - Environmental DNA UI - D000080309 MN - D13.444.308.577 MS - DNA found in the ENVIRONMENT that is from the residual biological materials of the organisms in the environment. HN - 2020 BX - DNA, Environmental FX - Metagenomics MH - Environmental Indicators UI - D000079264 MN - N6.850.460.350.80.625 MS - Data related to climate change, ozone layer depletion, eutrophication, acidification, toxic contamination, urban environmental quality, biodiversity, cultural landscapes, waste, water resources, forest resources, fish resources, and soil degradation including desertification and erosion. (from https://www.oecd.org/env/indicators-modelling-outlooks/37551205.pdfc). HN - 2020 FX - Environmental Biomarkers MH - Environmental Science UI - D000079265 MN - H1.345 MS - Scientific discipline that studies external factors, both biotic (living) and abiotic (nonliving), to which an organism is exposed. HN - 2020(2004) MH - Epigenome UI - D000081122 MN - G5.360.340.06 MS - A network of chemical compounds surrounding DNA that modify the genome without altering the DNA sequences and have a role in determining which genes are active in a cell. HN - 2020 BX - DNA Methylome BX - Methylome FX - Epigenesis, Genetic MH - Evidence-Based Pharmacy Practice UI - D000081142 MN - H2.249.937 MN - H2.646.125 MS - The practice of pharmacy in which the pharmacist makes decisions, taking into account the best available current research evidence, the pharmacist's expertise, and the needs and preferences of the patient. HN - 2020 BX - Evidence-Based Pharmaceutical Care BX - Evidence-Based Pharmacy MH - Exposome UI - D000081413 MN - N6.850.460.350.96 MS - The measure of all the exposures of an individual from all sources, including environmental and occupational sources, in a lifetime and how those exposures relate to health. (from https://www.cdc.gov/niosh/topics/exposome/ on 06/06/2019) HN - 2020 MH - Extranodal Extension UI - D000079822 MN - C4.697.650.280 MN - C23.550.727.650.280 MS - A penetration of LYMPH NODE metastatic cells through the nodal capsule into the perinodal fatty tissue used in a TUMOR STAGING system (the TNM staging system). HN - 2020 BX - Extracapsular Extension BX - Extranodal Tumor Deposits BX - Tumor Deposit MH - Extreme Hot Weather UI - D000081027 MN - G16.500.750.775.291.500 HN - 2020 MH - Extreme Weather UI - D000080165 MN - G16.500.275.63.725.232 MN - G16.500.750.775.291 MN - N6.230.300.100.725.193 MS - Events that have extreme values of important meteorological variables. Extreme is generally defined as either taking maximum values or exceedance above pre-existing high thresholds. Such events are generally rare; for example, extreme wind speeds exceeding the 100-year return value, which have a probability of only 0.01 of occurring in any particular year. (Stephenson, 2008) HN - 2020 MH - Familial Exudative Vitreoretinopathies UI - D000080345 MN - C11.250.345 MN - C11.270.238 MN - C11.768.337 MN - C16.131.384.424 MN - C16.320.290.352 MS - A group of inherited disorders characterized by incomplete development of the retinal vasculature. Its severity can vary from complete blindness in infancy, to mild or no visual problems, where small areas of vascular defects are observable only by FLUORESCEIN ANGIOGRAPHY. Exudative vitreoretinopathy 1 is associated with mutations in the FZD4 gene. HN - 2020(2014) BX - X-Linked Familial Exudative Vitreoretinopathy BX - XL-FEVR MH - Famine UI - D000079685 MN - J1.576.423.750.500 MS - The conditions when at least 20 per cent of households in an area face extreme food shortages with a limited ability to cope; acute malnutrition rates exceed 30 per cent; and the death rate exceeds two persons per day per 10,000 persons. (From news.un.org/en/story/2011/07/382342-when-food-security-crisis-becomes-famine) HN - 2020; 1986-2019 use STARVATION FX - Hunger FX - Starvation MH - Fatty Acid Elongases UI - D000081031 MN - D8.811.913.50.134.343 MS - Enzymes conserved from yeast to mammals which mediate elongation of FATTY ACIDS into very-long-chain fatty acids. HN - 2020 (2000) BX - ELOVL Proteins BX - Fatty Acid Elongation Enzyme MH - Ferroptosis UI - D000079403 MN - G4.146.954.178 MS - A form of REGULATED CELL DEATH initiated by oxidative perturbations of the intracellular microenvironment that is under constitutive control by glutathione peroxidase 4 and can be inhibited by iron chelators and lipophilic antioxidants. HN - 2020 MH - Fertility Clinics UI - D000080104 MN - N2.278.204 MS - Health clinics offering fertility treatment services. HN - 2020 BX - Infertility Clinics MH - Fictional Works as Topic UI - D000080503 MN - L1.178.682.192.459 MS - Works about creative writing, not presented as factual. HN - 2020 MH - Food Fussiness UI - D000081010 MN - F1.145.407.458 MS - Patterns associated with eating including modes of feeding, rhythmic patterns of eating, and time intervals. HN - 2020 BX - Picky Eating MH - Forensic Entomology UI - D000081230 MN - H1.158.273.943.409.500 MN - I1.198.780.906 MS - The use of insects and related arthropods that inhabit decomposing corpses or remains in the conduct of medico-legal or medico-criminal investigations. HN - 2020 MH - Formins UI - D000080865 MN - D5.750.78.730.333 MN - D12.776.220.525.333 MS - A family of multidomain microfilament proteins associated with ACTIN FILAMENTS. They generally have multiple Formin-Homology domains (e.g., FH2 domain) and additionally have a RhoGTPase-binding domain and a diaphanous inhibitory domain. Formins and homologs are involved in actin reorganization. HN - 2020 BX - DIAPH Protein 1 BX - DIAPH Protein 2 BX - DIAPH Proteins BX - Diaphanous-Related Formin Homology Proteins BX - Diaphanous-Related Formins BX - FMN Protein 1 BX - FMN Protein 2 BX - FMN Proteins BX - Formin 1 Protein BX - Formin 2 Protein BX - Formin Homology Proteins MH - Galagidae UI - D000080623 MN - B1.50.150.900.649.313.988.700.277 MS - A family of Primates of the suborder Strepsirhini containing six genera. The family is widely distributed in Africa near Subsaharan region. The six genera are: Euoticus (needle-clawed galagos), GALAGO (bush babies), Galagoides (dwarf galagos), Otolemur (greater galagos), Paragalago and Sciurocheirus (squirrel galagos). All are primarily arboreal and nocturnal. HN - 2020;for EUOTICUS use under GALAGOS 1981-2019 BX - Euoticus BX - Galagoides BX - Greater Galagos BX - Lesser Galagos BX - Needle-Clawed Galagos BX - Otolemur BX - Paragalago BX - Sciurocheirus BX - Squirrel Galagos MH - Gemtuzumab UI - D000079982 MN - D9.408.51.247.500 MN - D12.776.124.486.485.114.224.60.790 MN - D12.776.124.790.651.114.224.60.790 MN - D12.776.377.715.548.114.224.200.790 MS - Immunotoxin that consists of an anti-CD33 (CD33 ANTIGEN) monoclonal antibody conjugated to CALICHEAMICIN. It is used for the treatment of ACUTE MYELOID LEUKEMIA. HN - 2020 (2000) BX - Gemtuzumab Ozogamicin BX - Gemtuzumab-Ozogamicin MH - Genetic Introgression UI - D000079425 MN - E5.820.150.390.500 MN - G5.90.390.500 MS - The transfer of genetic material from one species to another by inter-species hybridization and repeated backcrossing. HN - 2020 FX - Gene Flow MH - Germinal Center Kinases UI - D000081410 MN - D8.811.913.696.620.682.700.397 MS - Serine-threonine kinases characterized by an N-terminal STE20 kinase domain. HN - 2020 BX - Germinal Center Kinase Family MH - Gingipain Cysteine Endopeptidases UI - D000080867 MN - D8.811.277.656.262.500.468 MS - Cysteine endoproteinases, from periodontal pathogen PORPHYROMONAS GINGIVALIS, acting as virulence factors associated with PERIODONTITIS. They are produced as pre-proproteins which mature into ARGININE and LYSINE specific endopeptidases. HN - 2020 BX - Arg-Gingipain BX - Arginine Gingipain BX - Gingipain K BX - Gingipain Proteases BX - KGP Protease BX - Lys-Gingipain BX - Lysine Gingipain BX - RGP-2 Gingipain BX - RGPB Protein MH - Globus Sensation UI - D000079564 MN - F3.875.300.500 MS - A feeling of a lump in the throat that occurs between meals in the absence of other gastrointestinal and motility disorders (e.g., DYSPHAGIA; GASTROESOPHAGEAL REFLUX). HN - 2020; use CONVERSION DISORDER 1980-2019 BX - Globus Hystericus MH - Hair Analysis UI - D000081205 MN - E1.370.225.124.385 MN - E1.370.390.288 MN - E5.200.124.385 MS - Examination of hair by chemical, physical, or microscopic means. HN - 2020 BX - Hair Mineral Analysis FX - Hair MH - Hamman-Rich Syndrome UI - D000080203 MN - C8.381.765.500.500 MS - Acute idiopathic interstitial pneumonitis characterized by diffuse PULMONARY ALVEOLI damage with uniform edematous connective tissue proliferation. It is often associated with extensive fibroblastic distortion of the lung parenchyma and leads to ADULT RESPIRATORY DISTRESS SYNDROME in later stages. HN - 2020; for HAMMAN-RICH SYNDROME use PULMONARY FIBROSIS 1984-2019; for HAMMAN-RICH SYNDROME use IDIOPATHIC PULMONARY FIBROSIS 2010-2019 BX - Acute Interstitial Pneumonia BX - Acute Interstitial Pneumonitis MH - Heme-Binding Proteins UI - D000081062 MN - D12.776.157.373 MN - D12.776.422.498 MS - Metalloproteins that contain a HEME ligand as the prosthetic group. HN - 2020(1984) BX - Heme-Binding Protein MH - Hepatic Infarction UI - D000081011 MN - C6.552.289 MN - C23.550.513.355.500 MN - C23.550.717.489.500 MS - Formation of infarct resulting from obstruction of HEPATIC ARTERY and/or PORTAL VEIN most often after LIVER TRANSPLANTATION or hepatobiliary surgery. HN - 2020 BX - Hepatic Infarct BX - Liver Infarct BX - Liver Infarction MH - Hereditary Complement Deficiency Diseases UI - D000081208 MN - C16.320.798.500 MN - C20.673.795.500 MS - Genetic disorders due to mutations in genes involved in COMPLEMENT SYSTEM PROTEINS. They are often classified into distinct pathway of complement activation where causative mutations are found (e.g., classical pathway, lectin pathway, alternative pathway, and terminal complement pathway). HN - 2020 BX - Complement Deficiencies BX - Inherited Complement Deficiency Diseases MH - Heterogeneous Nuclear Ribonucleoprotein D0 UI - D000081035 MN - D12.776.157.725.813.750.300.500 MN - D12.776.664.962.813.750.300.500 MS - Member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) specifically binds RNA molecules that contain AU RICH ELEMENTS found within the 3'-UTR of many PROTO-ONCOGENES and CYTOKINES mRNAs. It functions as a transcription factor, binds to double- and single-stranded DNA sequences in a specific manner. HN - 2020 (2001) BX - AU-rich Element RNA-binding Protein 1, 37 kDa BX - AUF1 Protein BX - AUF1A Protein BX - P37 AUF1 Protein MH - Historical Trauma UI - D000080037 MN - F2.830.900.500 MN - F3.950.750.375.500 MS - Clinical distress among descendants of survivors of mass trauma, as if they had suffered through the same extreme historic circumstances. Symptoms may persist through generations. HN - 2020 BX - Historic Trauma BX - Historical Psychological Trauma BX - Intergenerational Trauma BX - Transgenerational Trauma MH - Homeobox A10 Proteins UI - D000080905 MN - D12.776.260.400.226 MS - Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis of tissues. They bind to the DNA sequence 5'-AA[AT]TTTTATTAC-3'. HN - 2020 BX - Homeo Box A10 Proteins BX - Homeobox A10 BX - HOXA 10 Proteins BX - HOXA10 Proteins MH - Hormonal Contraception UI - D000080282 MN - E2.875.194.581 MS - Contraceptive methods that utilize HORMONAL CONTRACEPTIVE AGENTS. HN - 2020 BX - Contraception, Female Hormonal BX - Contraception, Hormonal BX - Contraception, Male Hormonal BX - Female Hormonal Contraception BX - Male Hormonal Contraception FX - Contraceptive Agents, Hormonal MH - Horticulture UI - D000080802 MN - I3.450.642.581 MN - J1.40.498 MS - Branch of agriculture which involves the cultivation of vegetables, flowers, or ornamental plants for food, industrial, medicinal, or aesthetic purposes. It does not include CROP PRODUCTION on a large scale. HN - 2020 BX - Arboriculture BX - Floriculture MH - Hot Melt Extrusion Technology UI - D000080048 MN - E5.916.840 MN - J1.897.360.500 MN - J1.897.836.500 MS - Solvent-free method for preparing numerous types of drug delivery systems and dosage forms for active pharmaceutical ingredients that have solubility issues. It involves pumping polymeric materials at temperatures above their glass transition temperature to mix in active pharmaceutical ingredients with or without binders thus forming an amorphous product with an increase in the dissolution profile for the active pharmaceutical ingredients. HN - 2020 BX - Hot Melt Extrusion MH - Hybrid Renal Replacement Therapy UI - D000079782 MN - E2.870.254 MN - E4.292.573 MS - Procedures involving non-continuous blood purification (e.g., dialysis, filtration or perfusion) via vascular access with settings for dialysate and blood flow rates and treatment duration settings hybrid between CRRT TECHNIQUE and IRRT TECHNIQUE. HN - 2020 BX - Extended Daily Dialysis BX - Hybrid Extracorporeal Therapy BX - Hybrid RRT BX - SLED Technique BX - SLEDD Technique BX - SLEDDF BX - Sustained Low-Efficiency Daily Diafiltration BX - Sustained Low-Efficiency Daily Dialysis BX - Sustained Low-Efficiency Dialysis MH - Hydrogen Deuterium Exchange-Mass Spectrometry UI - D000080307 MN - E5.196.344.500 MN - E5.196.566.550 MS - A mass spectrometry method utilizing hydrogen-deuterium exchange kinetics to study conformational and dynamic changes especially of proteins, such as interactions during ligand binding and allosteric effects during catalysis. HN - 2020 BX - H-D Exchange Mass Spectrometry BX - HDX-MS MH - Immunogenic Cell Death UI - D000079527 MN - G4.146.954.285 MS - A form of regulated cell death that results in release of specific DAMAGE ASSOCIATED MOLECULAR PATTERN MOLECULES which activate an ADAPTIVE IMMUNE RESPONSE. It can be initiated in any type of cell by a restricted set of stimuli, including viral infection, some chemotherapeutics or immunogenic radiation therapy. HN - 2020 MH - Indigenous Peoples UI - D000081034 MN - M1.686.754.254 MS - Descendants who self-identify as members of a group who inhabited a country or region at the time when people of different cultures or ethnic origins arrived. They often maintain their distinct language, culture, and beliefs. HN - 2020 BX - First Nation Peoples BX - Native Peoples MH - Indriidae UI - D000080544 MN - B1.50.150.900.649.313.988.700.354 MS - A family of primates of the superfamily LEMUROIDEA, suborder STREPSIRRHINI containing genera AVAHI (woolly lemurs); INDRI; and PROPITHECUS (sifakas). The family is distributed in Madagascar. HN - 2020(1981) BX - Avahi BX - Indri BX - Indri indri BX - Woolly Lemurs MH - Infratemporal Fossa UI - D000080884 MN - A1.456.830.600 MN - A2.835.232.781.750.700 MS - The compartment that lies posterior to the MAXILLA and inferior to the side wall of the SKULL deep to the ramus of the MANDIBLE. It contains several FACIAL NERVES and the CAROTID ARTERIES and the JUGULAR VEINS. AN - NIM when merely locational; neoplasms: coordinate with SKULL BASE NEOPLASMS HN - 2020 MH - Inotuzumab Ozogamicin UI - D000080045 MN - D9.408.51.247.750 MN - D12.776.124.486.485.114.224.60.794 MN - D12.776.124.790.651.114.224.60.794 MN - D12.776.377.715.548.114.224.200.794 MS - Immunotoxin that consists of anti-CD22 (CD22 ANTIGEN) humanized monoclonal antibody covalently linked to the antineoplastic antibiotic CALICHEAMICIN. It is used for the treatment of adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (LEUKEMIA, ACUTE LYMPHOBLASTIC). HN - 2020 (2004) BX - Besponsa MH - Intermittent Renal Replacement Therapy UI - D000079763 MN - E2.870.263 MN - E4.292.636 MS - Procedures with non-continuous blood purification (e.g., dialysis, filtration and/or perfusion) via vascular access by increasing blood flow rate compared to CONTINUOUS RRT. HN - 2020 BX - Accelerated Veno-Venous Hemofiltration BX - Accelerated Venovenous Hemofiltration BX - Intermittent RRT BX - Intermittent Veno-Venous Hemodiafiltration BX - Intermittent Venovenous Hemodiafiltration BX - IRRT Technique BX - PIRRT BX - Prolonged Intermittent Renal Replacement Therapy MH - Internet of Things UI - D000080487 MN - L1.224.230.110.500.657 MS - Networking capability which facilitates information flow to and from objects and devices using the INTERNET. HN - 2020 MH - Internet-Based Intervention UI - D000079382 MN - L1.224.230.110.500.688 MS - Use of the INTERNET to facilitate the dissemination of health-related information and to connect patients to support. HN - 2020 MH - Interosseous Membrane UI - D000080944 MN - A10.165.560 MS - A sheet of fibrous connective tissue rich in COLLAGEN often linking two parallel bony structures forming a syndesmosis type joint. It provides longitudinal stability, TENSILE STRENGTH, and weight distribution/transfer and may allow limited movement in syndesmoses. HN - 2020 MH - Interpersonal Psychotherapy UI - D000079062 MN - F4.754.506 MS - Interpersonal modification of psychodynamic psychotherapy. Therapy is present-focused and seeks to resolve problems in interpersonal relations. Aspects of attachment theory are used to analyze how past relationships affect current relationships. HN - 2020 MH - Intersex Persons UI - D000080183 MN - M1.777.250 MS - Those individuals with INTERSEX CONDITIONS, with or without a desire to undergo SEX REASSIGNMENT PROCEDURES. HN - 2020; was Transgender Persons 2013-2019 MH - Involuntary Commitment UI - D000079243 MN - E2.760.415.640 MS - Non-voluntary institutionalization or isolation following refusal or failure to take medication, to complete treatment, or to adhere to infection control precautions, or behavior that may or does endanger self or others. HN - 2020; use COMMITMENT OF MENTALLY ILL 1977-2019 MH - Jugular Foramina UI - D000080869 MN - A1.456.830.200.500 MN - A2.835.232.781.750.400.500 MS - A pair of openings from the posterior cranial fossa through which the GLOSSOPHARYNGEAL NERVE; VAGUS NERVE; ACCESSORY NERVE and the internal JUGULAR VEINS pass. HN - 2020 BX - Jugular Foramen MH - Lactate Dehydrogenase 5 UI - D000080864 MN - D8.811.682.47.551.400.500 MS - A member of the LACTATE DEHYDROGENASES isozyme family, Lactate Dehydrogenase 5 is localized to liver and skeletal muscle cells where its expression increases in liver disease and striated muscle trauma respectively. HN - 2020 (2000) BX - Lactate Dehydrogenase A BX - Lactate Dehydrogenase-M MH - Learning Health System UI - D000080891 MN - N4.590.374.395 MN - N5.300.504 MS - A system in which internal data and experience are systematically integrated with external evidence and that knowledge is put into practice. As a result, patients get higher quality, safer, more efficient care, and health care delivery organizations become better places to work. (https://healthit.ahrq.gov/health-care-theme/learning-health-system) HN - 2020 BX - Learning Health Community BX - Learning Healthcare System MH - Legal Epidemiology UI - D000080030 MN - I1.198.780.937.544 MN - N6.850.698 MS - Scientific study of law as a factor in the cause, distribution, and prevention of disease and injury. (From https://read.dukeupress.edu/jhppl/article/41/6/1151/40084/Policy-Surveillance-A-Vital-Public-Health-Practice). HN - 2020 BX - Policy Surveillance MH - Ligularia UI - D000079543 MN - B1.650.940.800.575.912.250.100.508 MS - A genus of ornamental plants in the family ASTERACEAE, often found near water. HN - 2020; use ASTERACEAE 2003-2019 MH - Limited English Proficiency UI - D000080031 MN - L1.143.230.750 MS - Limited ability to communicate with or understand English. HN - 2020 BX - Limited English Proficient MH - Lipidomics UI - D000081362 MN - H1.158.201.586.500 MN - H1.158.273.180.599.500 MN - H1.181.122.638.500 MS - A branch of metabolomics concerned with the study of global LIPIDS profiles in physiological systems. HN - 2020 BX - Lipidome MH - Locked-In Syndrome UI - D000080422 MN - C10.597.622.760.500 MN - C10.668.416 MN - C23.888.592.636.786.500 MS - Acquired neuromuscular disorder characterized by complete paralysis of voluntary muscles and lower CRANIAL NERVES except for limited voluntary eye movements. It is due to various cerebrospinal disconnections at or near the PONS and the POSTERIOR CRANIAL FOSSA, typically secondary to pontine hemorrhage or infarct. Because cognitive function is intact it is sometimes referred to as a pseudocoma state. HN - 2020(1981) BX - Cerebromedullospinal Disconnection BX - Ventral Pontine Syndrome MH - Lymph Node Ratio UI - D000080945 MN - E1.370.225.500.384.808 MN - E5.200.500.384.733 MN - E5.242.384.733 MS - The ratio of metastatic to total examined LYMPH NODES. HN - 2020 MH - Macaca arctoides UI - D000080531 MN - B1.50.150.900.649.313.988.400.112.199.120.510.260 MS - A species of the genus MACACA inhabiting India, China, and other parts of southern Asia. The species is characterized by its thick brown fur covering most of its body except the face and short tail. AN - NIM when experimental animal; diseases: coordinate with MONKEY DISEASES HN - 2020 BX - Bear Macaque BX - Brown Stump-tailed Macaque BX - M. arctoides BX - M. brunneus BX - M. speciosus BX - M. ursinus BX - Macacus brunneus BX - Macacus speciosus BX - Macacus ursinus BX - Stump-Tailed Macaque MH - Macaca fuscata UI - D000080527 MN - B1.50.150.900.649.313.988.400.112.199.120.510.535 MS - A species of the genus MACACA characterized by red naked face. M. fuscata is primarily ground-dwelling in forest and mountains often near hot springs in Japan. AN - NIM when experimental animal; diseases: coordinate with MONKEY DISEASES HN - 2020(1980) BX - Japanese Macaque BX - Japanese Monkey BX - M. fuscata BX - Macaca fuscata fuscata BX - Macaca fuscata yakui BX - Monkey, Japanese BX - Snow Monkey MH - Macroautophagy UI - D000080550 MN - G4.11.750 MS - The segregation of large parts of the cytoplasm, including ORGANELLES and PROTEIN AGGREGATES, into AUTOPHAGOSOMES and lysosomal degradation after fusion with LYSOSOMES. HN - 2020; use AUTOPHAGY 2017-2019 BX - Aggrephagy BX - Chaperone-Assisted-Selective Autophagy BX - Lysophagy BX - Macro-Autophagy BX - Pexophagy BX - Proteaphagy BX - Xenophagy MH - Mandibular Nerve Injuries UI - D000080902 MN - C7.465.299.625.500.349.750 MN - C10.292.200.875.750 MN - C10.292.319.625.700.349.750 MN - C10.900.300.218.775.750 MN - C26.915.300.400.825.750 MS - Traumatic injuries to the MANDIBULAR NERVE and its branches. Note that marginal mandibular nerve injury is a type of FACIAL NERVE INJURIES. Injuries to LINGUAL NERVE branch of mandibular nerve is LINGUAL NERVE INJURIES. HN - 2020 BX - Auriculotemporal Nerve Injuries BX - Buccal Nerve Injuries BX - Deep Temporal Nerve Injuries BX - Inferior Alveolar Nerve Injuries BX - Lateral Pterygoid Nerve Injuries BX - Masseteric Nerve Injuries BX - Mental Nerve Injuries MH - Maze Procedure UI - D000079042 MN - E4.14.640 MN - E4.100.376.602 MN - E4.928.220.465 MS - A surgical treatment in which heart tissue is scarred (cut-and-sew method), excised or otherwise destroyed in an open chest approach to direct electrical signals through a more controlled path via the ATRIOVENTRICULAR NODE. It is often used to restore normal rhythms in ATRIAL FIBRILLATION. HN - 2020 MH - Meibomian Gland Dysfunction UI - D000080343 MN - C11.338.780 MS - A chronic dysfunction of MEIBOMIAN GLANDS characterized by altered tear film stability and function due to a decrease or alteration in lipid quality/content in meibum. It is often associated with evaporative-type DRY EYE SYNDROME. HN - 2020 BX - MG Dysfunction MH - Mental Foramen UI - D000080383 MN - A2.835.232.781.324.502.632.800 MN - A14.521.632.800 MS - An opening on the anterolateral aspect of the MANDIBLE through which the mental nerve bundle and vessels exit. HN - 2020 BX - Mental Foramina MH - Microautophagy UI - D000080551 MN - G4.11.875 MS - A type of autophagy in which the cytoplasmic entities, such as parts of CELL NUCLEI; damaged MITOCHONDRIA; and lipid droplets, are taken up by small vesicles such as VACUOLES or MULTIVESICULAR BODIES, and degraded by lysosomal digestion. HN - 2020 BX - Chlorophagy BX - Endosomal Microautophagy BX - Micropexophagy BX - Piecemeal Microautophagy MH - Microgels UI - D000080386 MN - D5.750.217 MN - D20.280.320.531 MN - D25.720.501 MN - D26.255.165.320.531 MN - J1.637.51.720.562 MS - Three-dimensional biocompatible polymers in micrometer size range. They are typically spherical particles in a size range of 1-350 micrometers when used for drug delivery and 3D cell culture applications. HN - 2020 MH - Microplastics UI - D000080545 MN - D5.750.716.294 MN - D25.720.716.294 MN - J1.637.51.720.716.294 MS - Plastic particles, less than 5 millimeters in diameter, that are generated from the degradation of larger pieces or are manufactured to be microstructures or smaller. HN - 2020 BX - Mesoplastics BX - Plastic Microparticles BX - Plastic Nanoparticles FX - Microspheres MH - Microwave Imaging UI - D000080925 MN - E1.370.350.536 MS - Use of MICROWAVES as a diagnostic tool. HN - 2020 BX - Microwave Tomography MH - Military Health UI - D000079644 MN - N1.400.506 MS - The physical and mental conditions of MILITARY PERSONNEL, active duty and retired U.S. Military personnel and their dependents. HN - 2020 BX - Health of Military Personnel FX - Military Family FX - Military Personnel MH - Military Health Services UI - D000081322 MN - N2.421.497 MN - N4.452.523 MS - Services organized for the diagnosis and treatment of disease and the maintenance of health primarily of MILITARY PERSONNEL. HN - 2020 MH - Missed Diagnosis UI - D000081006 MN - N2.421.450.280.500 MS - Failure to identify or diagnose a medical condition at the time a health professional is acquainted with the symptoms. HN - 2020 BX - Missing Diagnosis MH - Mitochondrial Transmembrane Permeability-Driven Necrosis UI - D000079530 MN - G4.146.954.393 MS - A form of regulated cell death that is initiated by specific perturbations of the intracellular microenvironment such as severe OXIDATIVE STRESS and cytosolic CALCIUM overload, which result in osmotic breakdown of the MITOCHONDRIAL MEMBRANES. HN - 2020 MH - Monocyclic Sesquiterpenes UI - D000081222 MN - D2.455.849.765.521 MS - Sesquiterpene compounds that contain a single ring structure. HN - 2020 BX - Bisabolane Derivatives BX - Bisabolanes BX - Cyclofarnesane Derivatives BX - Cyclofarnesanes BX - Elemane Derivatives BX - Elemanes BX - Humalane Derivatives BX - Humalanes MH - Monoterpene Aldehydes and Ketones UI - D000081203 MN - D2.47.725 MN - D2.455.849.575.766 MN - D2.522.698 MS - Monoterpene compounds that include a double bonded oxygen attached to the one or more of the carbon atoms. HN - 2020 BX - Monoterpene Aldehydes BX - Monoterpene Ketones MH - Movable Books UI - D000080871 MN - V2.535 MS - Books having mechanisms or parts that move, or are moved by the reader. AN - INDEXER: do not use HN - 2020 BX - Animated Books BX - Manipulative Books BX - Moveable Books BX - Paper Manikins MH - Multifocal Choroiditis UI - D000080364 MN - C11.941.160.478.550 MN - C11.941.879.780.900.300.489 MN - C11.941.879.780.900.650.500 MS - A multifocal uveitis syndrome involving the RETINAL PIGMENT EPITHELIUM and capillary layer of the CHOROID. It is characterized by chronic UVEITIS and multiple CHOROID lesions referred to as white dots, blurry vision, floaters, sensitivity to light, blind spots, and eye discomfort. HN - 2020(2010) MH - Multifunctional Nanoparticles UI - D000080873 MN - J1.637.512.600.525 MS - Nanoparticles that are engineered to have two or more physical properties. HN - 2020 BX - Janus Nanoparticles BX - Janus Particles BX - Patchy Particles BX - Two-Faced Nanoparticles MH - Multiparametric Magnetic Resonance Imaging UI - D000081364 MN - E1.370.350.825.500.755 MS - Magnetic Resonance Imaging technique that combines functional imaging techniques such as diffusion-weighted imaging (DWI), dynamic contrast-enhanced imaging and magnetic spectroscopy. This technique is widely used for active surveillance in prostate cancer imaging. HN - 2020 BX - mp-MRI BX - mpMRI BX - Multiparametric MRI MH - Myosin VIIa UI - D000081412 MN - D5.750.78.730.475.875 MN - D8.811.277.40.25.193.750.937 MN - D12.776.210.500.600.735 MN - D12.776.220.525.475.875 MS - Also referred to as unconventional myosin VIIa, these are actin-based motor molecules with ATPase activity that function in intracellular movements (e.g., HAIR CELLS, AUDITORY). HN - 2020 BX - Myosin-VIIa BX - Unconventional Myosin VIIa MH - Myotoxicity UI - D000081030 MN - C5.651.682 MN - C10.668.491.628 MN - C23.550.706 MN - C25.100.828 MN - C26.733.411 MN - G1.750.748.500.411 MS - Damage to the muscle or its function secondary to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION. HN - 2020 BX - Drug Associated Myopathies BX - Drug Induced Myopathies BX - Drug Related Myopathies BX - Myalgia-Arthralgia Syndrome BX - Toxic Myopathies MH - Nanogels UI - D000080385 MN - D5.750.219 MN - D20.280.320.609 MN - D25.720.532 MN - J1.637.51.720.584 MN - J1.637.512.150.500 MN - J1.637.512.600.596 MS - Three-dimensional biocompatible materials formed by cross-linking a hydrophilic polymeric component (e.g., HYDROGELS). They are typically spherical particles in a size range of 20-250 nm when used for drug delivery applications. HN - 2020 BX - Nanocomposite Gels BX - Nanocomposite Hydrogels MH - Nanopore Sequencing UI - D000081414 MN - E5.393.760.560 MS - A sequencing protocol that drives nucleic acids (DNA or RNA) in an electric field through NANOPORES allowing single molecule sequence analysis. HN - 2020 MH - Narcotic-Related Disorders UI - D000079524 MN - C25.775.643 MN - F3.900.647 MS - Disorders related to or resulting from abuse or misuse of NARCOTICS. HN - 2020; NARCOTIC ABUSE use OPIOID-RELATED DISORDER 1997-2019 BX - Narcotic Abuse BX - Narcotic Addiction BX - Narcotic Dependence MH - National Program of Cancer Registries UI - D000079402 MN - I1.409.418.750.600.650.200.760 MN - N3.540.348.500.500.600.650.225.760 MS - A unit of the United States Centers for Disease Control and Prevention that supports the collection of high-quality data on cancer occurrence (including the type, extent, and location of the cancer), the type of initial treatment, and outcomes. AN - add UNITED STATES; research support by this agency is checked as RESEARCH SUPPORT, U.S. GOV'T, P.H.S.; CATALOGER: Use NAF entry HN - 2020 MH - Necroptosis UI - D000079302 MN - G4.146.954.500 MS - A form of regulated cell death initiated by perturbations of extracellular or intracellular homeostasis that trigger a specific cell death pathway involving the activation of RIPK3 and MLKL (mixed lineage kinase domain like pseudokinase). Morphological changes include cytoplasmic and organellar swelling, rupture of the PLASMA MEMBRANE, and CHROMATIN CONDENSATION. AN - do not confuse with NECROSIS the pathological process HN - 2020 MH - Neurosteroids UI - D000081227 MN - D27.505.519.625.544 MN - D27.505.696.577.544 MS - Endogenous compounds or drugs that affect neuronal excitability through modulation of specific ionotropic receptors (e.g., GABA-A RECEPTORS). Endogenous neurosteroids are steroid hormones de novo synthesized by neurons and glial cells from steroid metabolite precursors (e.g., PREGNENOLONE). HN - 2020(2010) BX - Neuro-Steroid BX - Neuro-Steroids BX - Neuroactive Steroids BX - Neurosteroid MH - Noninvasive Prenatal Testing UI - D000081182 MN - E1.370.225.500.384.100.396.500 MN - E1.370.225.562.375 MN - E1.370.225.998.54.396.500 MN - E1.370.378.630.724 MN - E5.200.500.384.100.396.500 MN - E5.200.998.54.396.500 MN - E5.242.384.100.396.500 MN - E5.393.435.375 MN - N2.421.308.430.250 MN - N2.421.726.233.221.375 MS - The analysis of cell-free fetal DNA or the DNA from fetal cells that are biopsied from a pregnant woman’s blood, to screen for genetically-determined traits and genetic abnormalities. HN - 2020 BX - Noninvasive Prenatal Diagnosis BX - Noninvasive Prenatal Screening BX - Prenatal Cell-Free DNA Screening BX - Prenatal cfDNA Screening MH - Nucleobindins UI - D000080866 MN - D12.776.157.125.588 MN - D12.776.260.623 MS - A DNA and calcium binding protein which plays a role in calcium homeostasis. HN - 2020 (2000) BX - CALNUC protein BX - Nucleobindin BX - Nucleobindin-1 protein MH - Nudiviridae UI - D000081342 MN - B4.280.543 MN - B4.525.573 MS - A family of ARTHROPOD viruses, including INSECT VIRUSES and crustacean viruses. They are rod-shaped, enveloped, and circular dsDNA viruses that share structural and replication characteristics with BACULOVIRIDAE. Genera include Alphanudivirus and Betanudivirus. HN - 2020; for ORYCTES VIRUSES use BACULOVIRIDAE 1991-2019 BX - Nudivirus BX - Nudiviruses BX - Oryctes Viruses MH - Obesity, Maternal UI - D000079262 MN - C13.703.417 MN - C18.654.726.500.633 MN - C23.888.144.699.500.125 MN - E1.370.600.115.100.160.120.699.500.312 MN - G7.100.100.160.120.699.500.312 MS - BODY MASS INDEX in PREGNANT WOMEN that is excessively above the recommended cut-off. HN - 2020 MH - Observational Studies, Veterinary as Topic UI - D000079223 MN - E5.318.372.250.750 MN - N5.715.360.330.250.750 MN - N6.850.520.450.250.750 MS - Works about clinical studies in which animal subjects may receive diagnostic, therapeutic, or other types of interventions and where the investigator does not assign subjects to specific interventions. AN - for general design, methodology, economics, etc. of veterinary observational studies; a different heading OBSERVATIONAL STUDY, VETERINARY is used for reports of a specific veterinary observational study HN - 2020 MH - Occlusion Bodies, Viral UI - D000081363 MN - A21.125 MS - A polyhedral or ovocylindrical shaped matrix composed of a single crystalline protein (OCCLUSION BODY MATRIX PROTEINS) in which VIRIONS are embedded. It is distinguished from the area of the CYTOPLASM or CELL NUCLEUS in which virus components are being synthesized and assembled, known as VIRAL INCLUSION BODIES. HN - 2020 BX - Occluded Virions BX - Occluded Virus BX - Occlusion Body, Viral BX - Occlusion-Derived Virion BX - Polyhedral Inclusion Bodies BX - Polyhedral Inclusion Body BX - Polyhedral Occlusion Bodies BX - Polyhedral Occlusion Body BX - Viral Occlusion Bodies BX - Viral Occlusion Body MH - Open Abdomen Techniques UI - D000080872 MN - E4.987.100.500 MS - Abdominal wound closure techniques in which the opening from a laparoscopic abdominal incision is left open, but covered, to reduce or prevent INTRA-ABDOMINAL HYPERTENSION. HN - 2020 BX - Open Abdomen Technique BX - Open Abdomen Therapy BX - Open Abdomen Treatment MH - Opioid Epidemic UI - D000080052 MN - N6.850.290.200.300 MS - Widespread use of OPIOIDS by disproportionately large numbers of individuals within a population, community, or region occurring within a relatively narrow window of time. HN - 2020 BX - Epidemic, Opioid BX - Opiate Epidemic BX - Opioid Crisis MH - Opioid-Induced Constipation UI - D000079689 MN - C23.888.821.150.500 MN - C25.775.643.250 MN - F3.900.647.250 MS - CONSTIPATION associated with the use of OPIOIDS. HN - 2020 BX - Narcotic Bowel Syndrome BX - Opiate-Induced Constipation MH - Optic Nerve Hypoplasia UI - D000080344 MN - C10.292.700.463 MN - C10.500.760 MN - C11.270.588 MN - C11.640.522 MN - C16.131.666.763 MN - C16.320.290.612 MS - A group of rare genetic disorders characterized by underdeveloped OPTIC NERVES, resulting in increased incidences of vision impairment, CONGENITAL NYSTAGMUS and STRABISMUS. It may be syndromic, and is often associated with CNS malformations. HN - 2020 BX - Superior Segmental Optic Hypoplasia BX - Superior Segmental Optic Nerve Hypoplasia MH - Organoiron Compounds UI - D000081503 MN - D2.691.713 MS - Organic compounds that contain iron in carbon-to-iron chemical bond. HN - 2020 MH - Ototoxicity UI - D000081015 MN - C9.218.788 MN - C23.550.753 MN - C25.100.656 MN - C26.733.650 MN - G1.750.748.500.650 MS - Damage to the EAR or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION. HN - 2020 BX - Drug-Induced Cochlear Toxicity BX - Drug-Induced Cochleotoxicity BX - Drug-Induced Otological Toxicity BX - Drug-Induced Ototoxicity BX - Drug-Induced Vestibular Toxicity BX - Drug-Induced Vestibulotoxicity BX - Drug-Related Cochlear Toxicity BX - Drug-Related Cochleotoxicity BX - Drug-Related Otological Toxicity BX - Drug-Related Ototoxicity MH - Pancreaticobiliary Maljunction UI - D000080222 MN - C6.130.120.250.640 MN - C6.198.964 MN - C16.131.314.778 MS - A group of anatomical variations in which the COMMON BILE DUCT and MAIN PANCREATIC DUCT are joined outside the duodenal wall often with abnormally long common channel rather than at the SPHINCTER OF ODDI. HN - 2020 BX - Anomalous Pancreaticobiliary Ductal Union MH - Pancreatitis, Acute Hemorrhagic UI - D000081032 MN - C6.689.750.325 MS - An acute INFLAMMATION of the PANCREAS in which the initial edematous pancreatitis evolved into necrosis accompanied by HEMORRHAGE. HN - 2020 BX - Haemorrhagic Pancreatitis BX - Hemorrhagic Pancreatitis BX - Pancreatitis, Acute Haemorrhagic MH - Para-Athletes UI - D000080050 MN - M1.72.500 MN - M1.150.738 MS - Physically disabled individuals who have developed skills, physical stamina and strength to participate in SPORTS or other physical activities. HN - 2020 BX - Para Athletes BX - Para-Athlete BX - Paralympian BX - Paralympians BX - Paralympic Athletes BX - Wheelchair Athletes MH - Parapharyngeal Space UI - D000080886 MN - A1.456.830.800 MN - A1.598.250 MN - A2.835.232.781.750.850 MS - The deep neck space near the PHARYNX located anterior to the ptyergomandibular raphe, posterior to the prevertebral fascia, inferior to the SKULL BASE, and superior to the HYOID BONE. Prestyloid parapharyngeal space contains cranial nerves IX, X, XI, XII and internal JUGULAR VEIN and internal CAROTID ARTERY. Poststyloid parapharyngeal space contains AURICULARTEMPORAL NERVE and MAXILLARY ARTERY and ascending pharyngeal artery. HN - 2020 BX - Carotid Space BX - Lateral Pharyngeal Space BX - Pharyngomaxillary Space BX - Post-styloid Compartment BX - Post-styloid Parapharyngeal Space BX - Poststyloid Compartment BX - Poststyloid Compartment of the Parapharyngeal Space BX - Poststyloid Parapharyngeal Space BX - Pre-styloid Compartment BX - Prestyloid Compartment BX - Prestyloid Compartment of the Parapharyngeal Space BX - Prestyloid Parapharyngeal Space MH - Parthanatos UI - D000079323 MN - G4.146.954.750 MS - A type of regulated cell death initiated by hyperactivation of POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1) as a consequence of DNA DAMAGE; OXIDATIVE STRESS; HYPOXIA; HYPOGLYCEMIA; or INFLAMMATION. This leads to DNA FRAGMENTATION and CHROMATIN condensation. HN - 2020 MH - Perfusion Index UI - D000081282 MN - E1.370.370.585 MS - The ratio of arterial blood flow (PULSATILE FLOW) to venous, capillary, and tissue blood flow (non-pulsatile blood flow) - as measured regionally or peripherally. HN - 2020 FX - Plethysmography MH - Perioperative Medicine UI - D000079645 MN - H2.403.675 MS - A medical specialty concerned with the patient before and after surgical procedures. HN - 2020 MH - Phenomics UI - D000080444 MN - H1.158.273.180.700 MN - H1.158.273.343.775 MS - The systematic study of how genetic information or GENOMICS translates into biochemical, metabolic and morphological traits of an organism. HN - 2020 FX - Phenotype MH - Phosphoinositide-3 Kinase Inhibitors UI - D000081082 MN - D27.505.519.389.736 MS - Agents that inhibit PHOSPHOINOSITIDE-3 KINASE activity. HN - 2020 MH - Phospholipid Hydroperoxide Glutathione Peroxidase UI - D000080662 MN - D8.811.682.732.925 MS - A selenoenzyme that converts GLUTATHIONE plus FATTY ACID HYDROPEROXIDES to GLUTATHIONE DISULFIDE plus hydroxy fatty acids and water. HN - 2020 (1990) BX - Glutathione Peroxidase 4 BX - GPX4 Phospholipid Hydroperoxide Glutathione Peroxidase BX - PH-GPeroxidase BX - PHGPx Enzyme BX - Phospholipid Hydroperoxide Glutathione Peroxidase GPX4 BX - Phospholipid-Hydroperoxide Glutathione Peroxidase BX - Selenium-Dependent Glutathione Peroxidase Type-4 MH - Pinales UI - D000080054 MN - B1.650.940.800.575.912.625 MS - Order of Conifers of the class Pinopsida, subdivision Spermatophytina, and division Tracheophyta. The distinguishing attribute of the Pinales is the reproductive structure known as a cone. HN - 2020 BX - Araucariales BX - Cupressales BX - Taxales MH - Polycyclic Sesquiterpenes UI - D000081223 MN - D2.455.849.765.674 MN - D4.663 MS - Sesquiterpenes that contain two or more ring structures HN - 2020 BX - Caryophyllane Derivatives BX - Caryophyllanes BX - Eremophilane Derivatives BX - Eremophilanes BX - Valerane Derivatives BX - Valeranes MH - Polyprenols UI - D000081026 MN - D2.33.687 MN - D2.455.849.728 MS - Long chain isoprene compounds that include a hydroxyl group at the terminal carbon atom. HN - 2020 BX - Long Chain Isoprenoid Alcohols BX - Polyisoprenoid Alcohols BX - Polyisoprenols BX - Polyprenoids BX - Polyprenol Derivatives MH - Pomegranate UI - D000079702 MN - B1.650.940.800.575.912.250.859.833.500.625 MS - A deciduous shrub or small tree in the family Lythraceae, order Myrtales, superorder Rosanae. It bears edible reddish-purple fruit berries with seeds and pulp produced from the ovary of a single flower. HN - 2020; use LYTHRACEAE 2001-2019 MH - Pork Meat UI - D000080305 MN - G7.203.300.600.813.500 MN - J2.500.600.813.500 MS - MEAT or flesh of a pig (Sus scrofa) used as food. HN - 2020; use RED MEAT 2016-2019 BX - Bacon BX - Cured Ham BX - Pig Meat MH - Post-Cardiac Arrest Syndrome UI - D000080942 MN - C10.228.140.199.850 MN - C14.280.778 MN - C14.907.725.638 MN - C23.550.767.877.625 MS - A reperfusion syndrome characterized by various pathophysiological processes after CARDIAC ARREST. It may include post-cardiac arrest brain injury (HYPOXIA-ISCHEMIA, BRAIN), cardiocirculatory dysfunction, (e.g., systemic ISCHEMIA), HYPERGLYCEMIA; MULTIPLE ORGAN FAILURE and delayed death. HN - 2020 BX - Postcardiac Arrest Syndrome BX - Postresuscitation Disease MH - Postoperative Cognitive Complications UI - D000079690 MN - C23.550.767.831 MN - F3.615.250.700.500 MS - COGNITIVE IMPAIRMENT or functional decline after a surgical procedure. HN - 2020 BX - Postoperative Cognitive Dysfunction BX - Postoperative Decline MH - Potassium Channels, Sodium-Activated UI - D000081033 MN - D12.776.157.530.400.600.950 MN - D12.776.543.550.450.750.950 MN - D12.776.543.585.400.750.950 MS - Potassium channels whose activation is dependent on intracellular sodium concentrations. HN - 2020 BX - K+ Channels, Sodium-Activated BX - Potassium Channels, Sodium-Dependent BX - Sodium-Activated Potassium Channel BX - Sodium-Activated Potassium Channels MH - Presbytini UI - D000080542 MN - B1.50.150.900.649.313.988.400.112.199.150.575 MS - The tribe of subfamily COLOBINAE, family CERCOPITHECIDAE. They are found in India, Indonesia, Malaysia, and Thailand. HN - 2020; for PRESBYTIS and PYGATHRIX use CERCOPITHECIDAE (1980-2019) BX - Asian Colobines BX - Douc Langurs BX - Douc Monkeys BX - Indian Langurs BX - Langurs BX - Lutungs BX - Nasalis BX - Presbytis BX - Proboscis Monkey BX - Pygathrix BX - Rhinopithecus BX - Semnopithecus BX - Simakobu BX - Simias BX - Simias concolor BX - Snub-Nosed Monkeys BX - Trachypithecus MH - Primary Immunodeficiency Diseases UI - D000081207 MN - C16.320.798 MN - C20.673.795 MS - Genetic immunologic deficiency diseases and syndromes due to mutations in genes involved in IMMUNITY generally characterized by an increased susceptibility to infectious diseases. They are often associated with AUTOIMMUNE DISEASE manifestations. HN - 2020 BX - Congenital Immunodeficiency Diseases BX - Congenital Immunodeficiency Disorders BX - Congenital Immunodeficiency Syndromes BX - Inherited Immunodeficiency Diseases BX - Inherited Immunodeficiency Disorders BX - Inherited Immunodeficiency Syndromes BX - Primary Antibody Deficiencies BX - Primary Antibody Deficiency Disorders BX - Primary Antibody Deficiency Syndromes BX - Primary Immune Deficiency BX - Primary Immune Deficiency Diseases BX - Primary Immune Deficiency Disorders BX - Primary Immune Deficiency Syndromes BX - Primary Immunodeficiency Disorders BX - Primary Immunodeficiency Syndromes MH - Protein-Arginine Deiminase Type 1 UI - D000080062 MN - D8.811.277.721.250 MS - A peptidylarginine deiminase isoenzyme. It is a post-translational modification enzyme that catalyzes the conversion of protein-bound ARGININE residues to CITRULLINE residues in a CALCIUM ion-dependent manner. It functions within the epidermis, targeting INTERMEDIATE FILAMENTS; KERATINS; and filaggrin for CITRULLINATION to promote epidermal cornification. HN - 2020 (1999) BX - PAD Type I BX - PADI1 Protein BX - Peptidyl Arginine Deiminase Type 1 BX - Peptidyl Arginine Deiminase Type I BX - Peptidylarginine Deiminase I BX - Peptidylarginine Deiminase Type 1 BX - Peptidylarginine Deiminase Type I BX - Protein Arginine Deiminase 1 BX - Protein Arginine Deiminase Type 1 BX - Protein Arginine Deiminase Type I BX - Protein-Arginine Deiminase Type I FX - Citrullination MH - Protein-Arginine Deiminase Type 2 UI - D000080064 MN - D8.811.277.721.313 MS - A widely expressed isoenzyme of peptidylarginine deiminase, a post-translational modification enzyme that catalyzes the conversion of protein-bound ARGININE residues to CITRULLINE residues in a CALCIUM ion-dependent manner. HN - 2020 BX - PADI2 Protein BX - Peptidyl Arginine Deiminase Type 2 BX - Peptidyl Arginine Deiminase Type II BX - Peptidylarginine Deiminase II BX - Peptidylarginine Deiminase Type 2 BX - Peptidylarginine Deiminase Type II BX - Protein Arginine Deiminase 2 BX - Protein Arginine Deiminase Type 2 BX - Protein Arginine Deiminase Type II BX - Protein-Arginine Deiminase Type II FX - Citrullination MH - Protein-Arginine Deiminase Type 3 UI - D000080063 MN - D8.811.277.721.375 MS - A post-translational enzyme that catalyzes the conversion of protein bound arginine residues to CITRULLINE residues in a CALCIUM ion-dependent manner. PADI3 is a peptidylarginine deiminase isoenzyme expressed in epidermal tissue. HN - 2020 (1999) BX - PADI3 Protein BX - Peptidyl Arginine Deiminase Type 3 BX - Peptidyl Arginine Deiminase Type III BX - Peptidylarginine Deiminase III BX - Peptidylarginine Deiminase Type 3 BX - Peptidylarginine Deiminase Type III BX - Protein Arginine Deiminase 3 BX - Protein Arginine Deiminase Type 3 BX - Protein Arginine Deiminase Type III BX - Protein-Arginine Deiminase Type III FX - Citrullination MH - Protein-Arginine Deiminase Type 4 UI - D000080002 MN - D8.811.277.721.500 MS - A histone modification enzyme, which converts both ARGININE and monomethyl-arginine to CITRULLINE. It is one of several protein-arginine deiminase isoenzymes. It is a gene regulator involved in APOPTOSIS and CELL DIFFERENTIATION and a potential therapeutic target for the treatment of a variety of diseases. HN - 2020 (2004) BX - PAD V Enzyme BX - PADI4 Protein BX - PADI5 Protein BX - Peptidyl Arginine Deiminase Type 4 BX - Peptidyl Arginine Deiminase Type IV BX - Peptidylarginine Deiminase IV BX - Peptidylarginine Deiminase Type 4 BX - Peptidylarginine Deiminase Type IV BX - Peptidylarginine Deiminase V BX - Protein Arginine Deiminase 4 BX - Protein Arginine Deiminase Type 4 BX - Protein Arginine Deiminase Type IV BX - Protein-Arginine Deiminase Type IV FX - Citrullination MH - Protein-Arginine Deiminase Type 6 UI - D000080065 MN - D8.811.277.721.438 MS - A peptidylarginine deiminase isoenzyme mainly expressed in egg and embryo tissues. It is a post-translational modification enzyme that catalyzes the conversion of protein-bound ARGININE residues to CITRULLINE residues in a CALCIUM ion-dependent manner. HN - 2020 BX - PADI6 Protein BX - Peptidyl Arginine Deiminase Type 6 BX - Peptidyl Arginine Deiminase Type VI BX - Peptidylarginine Deiminase Type 6 BX - Peptidylarginine Deiminase Type VI BX - Peptidylarginine Deiminase VI BX - Protein Arginine Deiminase 6 BX - Protein Arginine Deiminase Type 6 BX - Protein Arginine Deiminase Type VI BX - Protein-Arginine Deiminase Type VI FX - Citrullination MH - Psychological Distress UI - D000079225 MN - F1.470.315 MS - Negative emotional state characterized by physical and/or emotional discomfort, pain, or anguish. HN - 2020 BX - Emotional Stress MH - Psychology, Positive UI - D000080032 MN - F4.96.628.57 MS - The scientific study of the strengths that enable individuals and communities to thrive. It is founded on the belief that people want to lead meaningful and fulfilling lives, to cultivate what is best within themselves, and to enhance their experiences of love, work, and play. (https://ppc.sas.upenn.edu/) HN - 2020 BX - Positive Psychology FX - Optimism MH - Public Nondiscrimination Policies UI - D000080033 MN - I1.655.500.608.550 MS - Policies that include the existence of a body responsible for the articulation and implementation of a platform based on an equality perspective that requires the integration of race-ethnicity, differences in sexual orientation, as well as the demands and needs arising from differences within the executive. Its objective is to translate a programmatic vision into action and action axes that reflects the struggle for egalitarian social relations. (From http://bit.ly/28WAaYO) HN - 2020 MH - Public Reporting of Healthcare Data UI - D000079204 MN - N5.700.712 MS - Required public availability of quality indicators data from health facilities. HN - 2020 MH - Pulmonary Arterial Hypertension UI - D000081029 MN - C8.381.423.847 MS - A progressive rare pulmonary disease characterized by high blood pressure in the PULMONARY ARTERY. HN - 2020 MH - Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase UI - D000081382 MN - D8.811.913.696.620.682.700.783 MS - A pyruvate dehydrogenase kinase isozyme located in the mitochondria which converts PYRUVATE to ACETYL CoA in the CITRIC ACID CYCLE, phosphorylates SERINE residues on pyruvate dehydrogenase using ATP, and plays a key role in the regulation of GLUCOSE and fatty acid metabolism. HN - 2020(1972) BX - PDH Kinase BX - Pyruvate Dehydrogenase (Lipoamide) Kinase BX - Pyruvate Dehydrogenase Acetyl-Transferring Kinase BX - Pyruvate Dehydrogenase Kinase MH - Quaternary Prevention UI - D000081404 MN - N2.421.726.784 MN - N4.590.374.675 MN - N5.300.703 MN - N6.850.780.715 MS - Actions taken to protect individuals (i.e. persons/patients) from unnecessary medical interventions that are likely to cause more harm than good. HN - 2020 FX - Medical Overuse MH - R-Loop Structures UI - D000080870 MN - G2.111.570.820.486.690 MN - G5.360.580.690 MS - An RNA-DNA hybrid structure formed when newly transcribed RNA remains bound to its DNA template. Stability of R-loops may play a role in GENETIC INSTABILITY. HN - 2020 BX - R-Loops MH - Randomized Controlled Trial, Veterinary UI - D000081262 MN - V3.175.375.500 MS - A work that reports on a clinical trial with animal subjects that involves at least one test treatment and one control treatment, concurrent enrollment and follow-up of the test- and control-treated groups, and in which the treatments to be administered are selected by a random process, such as the use of a random-numbers table. AN - this heading is used as a Publication Type; for original report of the conduct or results of a specific randomized veterinary clinical trial; a different heading CLINICAL TRIALS, VETERINARY AS TOPIC + RANDOMIZATION is used for general design, methodology, economics, etc. of randomized veterinary clinical trials HN - 2020 BX - Veterinary Randomized Controlled Trial MH - Rapid Sequence Induction and Intubation UI - D000079603 MN - E2.41.500.737 MN - E2.585.578.737 MN - E5.497.578.737 MS - A method of maintaining airway patency and administering anesthesia during emergency situations when it cannot be determined if the patient is fasting or not; or in other instances where there is a risk of aspiration. The method includes a series of events that involve the administration of SEDATIVES to induce unconsciousness, followed by NEUROMUSCULAR BLOCK AGENTS to improve the intubating conditions, followed by endotracheal intubation. HN - 2020 MH - Regulated Cell Death UI - D000079404 MN - G4.146.954 MS - Genetically encoded mechanisms in multicellular and unicellular eukaryotes that function to eliminate cells that are superfluous either during development, or to maintain tissue and organism homeostasis; and cells that are irreversibly damaged, abnormal, and/or potentially harmful. AN - general or unspecified, prefer specifics HN - 2020 MH - Relational Autonomy UI - D000080105 MN - K1.752.566.479.830.650.500 MN - N5.350.958.650.500 MS - The social context within which all individuals exist and acknowledge the emotional and embodied aspects of decision-makers. The approach acknowledges the central role of others in decision-making, including clinicians, who have a responsibility to engage patients’ and surrogates’ emotional experiences. HN - 2020 MH - Relative Energy Deficiency in Sport UI - D000080822 MN - F3.400.937 MS - Health disorders associated with low caloric intake of individuals involved in high-activity SPORTS. HN - 2020 BX - RED-S BX - RED-S Relative Energy Deficiency in Sport MH - Retinal Arterial Macroaneurysm UI - D000080346 MN - C11.768.346.500 MN - C14.907.55.908 MN - C14.907.489.815.500 MS - An acquired dilation of the retinal artery often associated with systemic HYPERTENSION. HN - 2020 BX - Retinal Arteriolar Macroaneurysm BX - Retinal Macroaneurysm BX - Ruptured Retinal Arterial Macroaneurysm MH - Ribosomal Protein L10 UI - D000080882 MN - A11.284.430.214.190.875.811.870.350 MS - A RIBOSOMAL PROTEIN which plays a crucial role in protein synthesis and embryonic brain development. Diseases associated with RPL10 mutations include Mental Retardation, X-Linked, Syndromic, 35 and Autism X-Linked 5. HN - 2020 (2002) BX - 60S Ribosomal Protein L10 BX - L10 Ribosomal Protein BX - QM Protein BX - QM Tumor Suppressor Protein BX - Tumor Suppressor QM MH - Right to Health UI - D000080564 MN - I1.880.604.473.688 MN - N3.706.437.688 MN - N4.590.374.350.750 MS - Right to accessible health services physically within reach for all sections of the population, including children, adolescents, older persons, persons with disabilities and other vulnerable groups as well as financially and on the basis of non-discrimination. Accessibility also implies the right to seek, receive and impart health-related information in an accessible format for all, including persons with disabilities, but does not impair the right to have personal health data treated confidentially. HN - 2020 BX - Health Rights BX - Healthcare Rights BX - Right to Health Care BX - Right to Healthcare MH - Right to Work UI - D000081202 MN - I1.880.604.473.694 MN - N3.706.437.694 MS - The right of individuals to work, to free choice of employment, to just and favorable conditions of work and to protection against unemployment. HN - 2020 BX - Right To Employment MH - RNA, Circular UI - D000079962 MN - D13.444.735.32 MS - RNA molecules in which the 3' and 5' ends are covalently joined to form a closed continuous loop. They are resistant to digestion by EXORIBONUCLEASES. HN - 2020 (1979) BX - circRNA BX - circRNAs BX - Circular Intronic RNA BX - Circular RNA BX - Circular RNAs BX - ciRNA BX - Closed Circular RNA MH - RNA-Seq UI - D000081246 MN - E5.393.332.250 MN - E5.393.760.319.500 MN - E5.393.760.710.500 MS - High-throughput nucleotide sequencing techniques developed for determining and analyzing the composition of the TRANSCRIPTOME of a sample. HN - 2020 BX - Whole Transcriptome Shotgun Sequencing MH - Rumination Syndrome UI - D000079562 MN - C6.405.609 MN - F3.400.968 MS - A gastrointestinal disorder characterized by repetitive and effortless regurgitation of ingested food from the stomach to the oral cavity in the early POSTPRANDIAL PERIOD. It is associated with functional gastrointestinal pathology (e.g., increased intra-gastric pressure) and psychiatric disorders (e.g., anxiety, depression). It is not limited to infants and distinct from GERD and VOMITING. HN - 2020(1998) BX - Rumination Disorders MH - Salads UI - D000080682 MN - G7.203.300.756 MN - J2.500.756 MS - A prepared mixture of cooked and/or raw vegetables, FRUIT, or other foods, garnished with a dressing CONDIMENT, and eaten as a MEAL or side dish. HN - 2020 BX - Salad MH - Sand UI - D000080463 MN - D20.721.750 MN - G1.311.330.500 MN - G1.311.820.750 MN - G16.500.275.815.750 MN - G16.500.320.500 MN - N6.230.600.750 MS - A hard granular material that is a component of soil. It is composed of very small pieces (between 0.06 and 2.0 millimeters in diameter) of disintegrating rock. HN - 2020 MH - Sapajus UI - D000080523 MN - B1.50.150.900.649.313.988.400.600.150.170.560 MS - A genus of the family CEBIDAE, subfamily CEBINAE, consisting of capuchin monkeys with characteristic tufts of hair over the eyes and sides of the head. Many were formerly classified under genus CEBUS. Sapajus inhabits the forests of Central and South America. AN - NIM when experimental animal; diseases: coordinate with MONKEY DISEASES HN - 2020 BX - Blond Capuchin BX - C. flavius BX - Cebus elegans BX - Cebus flavius BX - Cebus xanthosternos BX - Robust Capuchins BX - S. cay BX - S. flavius BX - Sapajus cay BX - Sapajus flavius BX - Sapajus xanthosternos BX - Tufted Capuchins BX - Yellow-Breasted Capuchin MH - Sapajus apella UI - D000080522 MN - B1.50.150.900.649.313.988.400.600.150.170.560.500 MS - A species of the genus SAPAJUS, subfamily CEBINAE, family CEBIDAE, consisting of tufted capuchin monkeys with characteristic black head cap and sideburn coloration with tufts of dark fur above the ears. S. apella was known as Cebus apella and C. a. apella. AN - NIM when experimental animal; diseases: coordinate with MONKEY DISEASES HN - 2020 BX - Cebus apella BX - Cebus apella macrocephalus BX - Guianan Brown Capuchin BX - Tufted Capuchin Monkeys MH - School Mental Health Services UI - D000079691 MN - N2.421.461.581 MN - N2.421.726.809.659 MN - N4.880 MS - Services which focus on the mental well-being of pre-college and pre-university students that include COUNSELING and therapy. HN - 2020 BX - School-Based Mental Health Services MH - Scope of Practice UI - D000079103 MN - F1.829.316.616.625.800 MS - The services that licensed professionals are deemed competent to perform, and permitted to undertake in keeping with the terms of their professional license. HN - 2020 MH - Sea Level Rise UI - D000080763 MN - G1.311.625.770 MN - G16.500.175.374.750 MN - G16.500.971.500 MS - An increase in the volume of the oceans and seas causing an elevation of the air-sea interface. HN - 2020 BX - Rising Sea Level BX - Sea-Level Rise MH - SecA Proteins UI - D000081416 MN - D8.811.277.40.25.494 MS - ATPases that provide energy for the translocation of proteins across bacterial PLASMA MEMBRANES and THYLAKOID membranes, by the SEC TRANSLOCATION CHANNELS. SecA is a component of the bacterial preprotein translocase which is comprised of SecA, the SECYEG TRANSLOCON, and the accessory domain proteins SecD, SecF, YajC, and YidC. HN - 2020 BX - SecA Protein MH - Securinega UI - D000079883 MN - B1.650.940.800.575.912.250.859.797.438.781 MS - A plant genus of the family EUPHORBIACEAE, order MALPIGHIALES. Members contain securinine and virosecurinine compounds. HN - 2020; use EUPHORBIACEAE 2003-2019 MH - Sennosides UI - D000081226 MN - D2.455.426.559.847.117.159.750.500 MN - D2.806.100.750.500 MN - D9.408.827 MN - D20.215.784.500.860.500 MS - Medications derived from SENNA EXTRACT that are used to treat CONSTIPATION. HN - 2020 (1973) BX - Senna BX - Senna Glycoside BX - Sennoside BX - Sennoside A Calcium BX - Sennoside A Calcium and Sennoside B Calcium BX - Sennoside A&B BX - Sennoside A&B, Calcium Salt BX - Sennoside A+B Calcium BX - Sennoside A, Calcium Salt BX - Sennoside A, Calcium Salt (1:1) BX - Sennoside B Calcium BX - Sennoside B, Calcium Salt BX - Sennosides A and B BX - Sennosides A and B Acids MH - Shape Memory Alloys UI - D000080743 MN - D1.552.33.769 MN - D5.937.250 MN - D25.58.664 MN - D25.860.250 MN - D27.720.102.751.250 MN - J1.637.51.58.664 MN - J1.637.51.860.250 MS - ALLOYS designed to recover their original shape upon heating. HN - 2020 BX - Shape-Memory Alloys MH - Shared Medical Appointments UI - D000079142 MN - E2.760.823 MN - N4.452.95.369 MN - N4.452.758.708.450.750 MS - Clinical encounters in which patients receive healthcare from one or more health professionals, in a group setting. These may include patient education and counseling, physical examination, and clinical support. Patients usually share a mutual attribute such as a medical condition. HN - 2020 MH - Shoulder Dystocia UI - D000080883 MN - C13.703.420.288.364 MS - Obstetric complication during OBSTETRIC DELIVERY in which exit of the fetus is delayed due to physical obstruction involving fetal shoulder(s). HN - 2020 BX - Fetal Shoulder Dystocia MH - Shwachman-Diamond Syndrome UI - D000081003 MN - C6.689.276.500 MN - C15.378.190.223.500.875 MN - C18.452.584.718.875 MS - An inherited syndrome characterized by EXOCRINE PANCREATIC INSUFFICIENCY; hematologic abnormalities (e.g., bone marrow hypoplasia), and skeletal abnormalities (e.g., metaphyseal chondroplasia). GERMLINE MUTATIONS in the SBDS gene are associated with Shwachman-Diamond Syndrome. HN - 2020(2014) BX - Pancreatic Insufficiency and Bone Marrow Dysfunction BX - Shwachman Diamond Syndrome BX - Shwachman Syndrome BX - Shwachman-Bodian Syndrome MH - Sialyl Lewis X Antigen UI - D000080506 MN - D23.50.285.50.50.500 MN - D23.50.301.264.900.50.500 MN - D23.50.301.264.965.500.500 MN - D23.50.301.290.544.59.500 MN - D23.50.550.325.50.500 MN - D23.50.705.230.544.59.500 MN - D23.101.100.900.50.500 MN - D23.101.140.75.50.500 MS - A sialylated version of Lewis X antigen expressed on cell surfaces. It is a ligand for SELECTINS. HN - 2020 (2008) BX - 5-Acetylneuraminyl-(2-3)-Galactosyl-(1-4)-(Fucopyranosyl-(1-3))-N-Acetylglucosamine BX - CD15s Antigen BX - Sialyl Le(x) BX - Sialyl Lewis X BX - Sialyl Lewis(x) Antigen BX - Sialyl Lewis(x) Tetrasaccharide BX - Sialyl SSEA-1 BX - Sialyl Stage-Specific Embryonic Antigen-1 BX - Sialyl-Lex BX - Sialylated Lewis X Antigen MH - Single-Case Studies as Topic UI - D000080907 MN - E5.318.372.250.250.682 MN - N5.715.360.330.250.250.682 MN - N6.850.520.450.250.250.682 MS - Trials that consider an individual patient as the sole unit of observation in a study investigating the efficacy or side-effects of different interventions to determine the optimal intervention for an individual patient using objective data-driven criteria. HN - 2020 BX - N-of-1 Trials as Topic BX - Single-Case Study BX - Single-Case Trial BX - Single-Subject Trial MH - Sino-Japanese War UI - D000081002 MN - I1.880.735.950.250.868 MN - K1.400.504.968.725 MS - Military conflict involving China and Japan 1937 - 1945. HN - 2020 BX - 2nd Sino-Japanese War BX - Second Sino-Japanese War 1937-1945 BX - Sino-Japanese War 1937-1945 MH - Sino-Nasal Outcome Test UI - D000079602 MN - E5.318.308.980.344.500.500 MN - N3.349.380.210.750.500 MN - N4.761.559.590.399.875.500 MN - N5.425.210.500.500 MN - N5.715.360.300.800.344.500.500 MN - N5.715.360.575.575.399.875.500 MN - N6.850.520.308.980.344.500.500 MS - Patient-reported measure of outcome in sino-nasal disorders such as rhinosinusitis and nasal polyposis. HN - 2020 MH - SLC31 Proteins UI - D000080083 MN - D12.776.157.530.450.250.578.875 MN - D12.776.157.530.937.640 MN - D12.776.543.585.450.250.578.875 MN - D12.776.543.585.937.762 MS - Eukaryotic copper transport proteins that function primarily in the transport of dietary or environmental COPPER. HN - 2020 BX - Solute Carrier Family 31 Proteins MH - Smart Glasses UI - D000080310 MN - E7.305.906.750 MN - L1.224.230.260.550.750 MS - Computerized eyewear with multiple technological applications for advanced computing and interoperability. Smart glasses are optimized to facilitate information and data access, capture, display, transfer, and manipulation. HN - 2020 BX - Google Glass BX - Head Mounted Display BX - Head Up Display BX - Head Worn Display BX - Smartglasses MH - Smart Materials UI - D000080745 MN - D5.937 MN - D25.860 MN - D27.720.102.751 MN - J1.637.51.860 MS - Materials designed to change properties in response to changes in their environment adopting various predetermined shapes and/or functionalities. HN - 2020 BX - Actuating Materials BX - Adaptive Materials BX - Intelligent Materials BX - Sensing Materials BX - Shape Memory Materials BX - Shape Memory Polymers BX - Shape-Memory Materials BX - Shape-Memory Polymers MH - Social Integration UI - D000080442 MN - F1.829.401.694 MS - A dynamic and principled process where all members participate in dialogue to achieve and maintain peaceful social relations. It does not include coerced assimilation or forced integration. (from https://www.un.org/esa/socdev/sib/peacedialogue/soc_integration.htm) HN - 2020 MH - Space Research UI - D000080546 MN - H1.770.644.966 MS - Studies of interactions between living organisms and characteristics of the extraterrestrial environment. These studies specifically address the structure and function of living organisms in an extraterrestrial environment and interdependent relationships of organisms with each other and/or the extraterrestrial environment while also touching on the origin, evolution and potential for extraterrestrial life. (From www.nasa.gov/audience/foreducators/spacelife/) HN - 2020 FX - Exobiology MH - Specific Language Disorder UI - D000080888 MN - C10.597.606.150.500.550.500 MN - C23.888.592.604.150.500.550.500 MN - C23.888.592.604.150.550.600 MS - Language disorder that delays the mastery of oral language skills or in children who have no hearing loss or other developmental delays. HN - 2020 BX - Specific Language Impairment FX - Language Development Disorders MH - Sphingosine 1 Phosphate Receptor Modulators UI - D000081243 MN - D27.505.519.947 MN - D27.505.696.477.656.875 MS - Agents that affect the function of G-protein coupled SPHINGOSINE 1-PHOSPHATE RECEPTORS. Their binding to the receptors blocks lymphocyte migration and are often used as IMMUNOSUPPRESSANTS. HN - 2020 BX - Sphingosine Receptor Modulators MH - Sphingosine Phosphorylcholine Receptors UI - D000081022 MN - D12.776.543.750.695.420.500.250 MS - A subfamily of lysophospholipid receptors with specificity for lysophosphatidic acid. HN - 2020; use RECEPTORS, LYSOSPHINGOLIPID 2005-2019 MH - Sphingosine-1-Phosphate Receptors UI - D000081025 MN - D12.776.543.750.695.420.500.500 MS - A subfamily of lysophospholipid receptors with specificity for sphingosine-1-phosphate (e.g., FINGOLIMOD), sphinganine 1-phosphate, 4-hydroxysphinganine 1-phosphate. HN - 2020; use RECEPTORS, LYSOSPHINGOLIPID 2005-2019 BX - Sphingosine-1-Phosphate Receptor 2 BX - Sphingosine-1-Phosphate Receptor 3 BX - Sphingosine-1-Phosphate Receptor 4 BX - Sphingosine-1-Phosphate Receptor 5 BX - Sphingosine-1-Phosphate Receptor1 MH - Squamous Intraepithelial Lesions UI - D000081483 MN - C23.149.688 MS - A cytological test finding that shows abnormal lesions of SQUAMOUS EPITHELIAL cells. HN - 2020 (2015) MH - Stargardt Disease UI - D000080362 MN - C11.270.872 MN - C11.768.585.439.339 MN - C16.320.290.724 MS - A juvenile-onset macular dystrophy characterized by progressive loss of VISUAL ACUITY with normal acuity in peripheral VISUAL FIELDS. Other associated clinical features may include LIPOFUSCIN fundus autofluorescence, atrophy of the RETINAL PIGMENT EPITHELIUM, loss of color vision, PHOTOPHOBIA and PARACENTRAL SCOTOMA. Germline mutations in the ABCA4 gene have been identified in recessive and dominant diseases. HN - 2020(2010) BX - Juvenile Macular Degeneration BX - Stargardt Disease 1 MH - Stilbestrols UI - D000081225 MN - D2.455.426.559.389.150.700.725 MS - Stilbene derivatives the contain one or more hydroxyl groups attached to the benzene ring structures. HN - 2020 BX - Hydroxyl-Stilbenes BX - Hydroxystilbene Derivatives MH - Stimuli Responsive Polymers UI - D000080762 MN - D5.750.950 MN - D5.937.500 MN - D25.720.950 MN - D25.860.500 MN - D27.720.102.751.500 MN - J1.637.51.720.950 MN - J1.637.51.860.500 MS - Polymeric materials designed to change properties in response to a stimulus. HN - 2020 BX - Smart Polymers BX - Stimuli Responsive Materials BX - Stimuli-Responsive Materials BX - Stimuli-Responsive Polymers BX - Stimuli-Sensitive Polymers BX - Stimulus-Responsive Polymers MH - Sudden Unexpected Death in Epilepsy UI - D000080485 MN - C10.228.140.490.746 MN - C23.550.260.322.812 MS - Sudden death in a patient with EPILEPSY associated with SEIZURES and seizure-related symptoms (e.g., APNEA; HYPOXEMIA) without other identifiable accidental causes (e.g., DROWNING; WOUNDS AND INJURIES). HN - 2020 BX - SUDEP MH - Sugar-Sweetened Beverages UI - D000080845 MN - G7.203.100.772 MN - J2.200.772 MS - Liquids or drinks sweetened with added sugars of various forms. HN - 2020 BX - Sugar-Added Beverages BX - Sugar-Sweetened Sodas BX - Sugar-Sweetened Soft Drinks BX - Sweetened Beverages BX - Sweetened Drinks MH - Suicide, Completed UI - D000081013 MN - F1.145.126.980.875.800 MN - I1.880.735.856.800 MS - The successful attempt to kill oneself. HN - 2020 BX - Completed Suicide MH - Synesthesia UI - D000080311 MN - C10.597.606.762.850 MS - The experience of involuntary sensory cross activation where the presentation of a particular stimulus elicits a secondary sensory-perceptual experience. It most commonly occurs in the association of color with linguistic stimuli such as letters, numbers, words, or music, but can also occur between other senses. Although synesthesia can be acquired or transient due to trauma or drug use, there is also a strong genetic component, with a prevalence of about 1 in 2,000 individuals and a female to male ratio of 6:1. HN - 2020(2011) BX - Chromesthesia BX - Colored Hearing Synesthesia BX - Grapheme-Color Synesthesia BX - Ideaesthesia BX - Ideasthesia BX - Lexical-Gustatory Synesthesia MH - Synucleinopathies UI - D000080874 MN - C10.574.928 MN - C18.452.845.650 MS - Neurodegenerative disorders involving deposition of abnormal ALPHA-SYNUCLEIN in dopaminergic neurons and glial cells in the brain. Pathological aggregations of alpha-synuclein proteins results in LEWY BODIES and Lewy neurites; melanin granules in the SUBSTANTIA NIGRA and LOCUS COERULEUS; and glial cytoplasmic inclusions. Synucleinopathies are associated with mutation in the ALPHA-SYNUCLEIN (SNCA) gene on chromosome 4. PARKINSON DISEASE; LEWY BODY DISEASE with dementia; and MULTIPLE SYSTEM ATROPHY are prominent examples of synucleinopathy. HN - 2020 BX - a-Synucleinopathies BX - alpha Synuclein Pathology BX - alpha-Synucleinopathies FX - alpha-Synuclein FX - Lewy Bodies MH - Tithonia UI - D000079542 MN - B1.650.940.800.575.912.250.100.906 MS - A genus of flowering plants in the ASTERACEAE family. It is found in MEXICO; CENTRAL AMERICA; and SOUTHWESTERN UNITED STATES. HN - 2020; use ASTERACEAE 2003-2019 MH - Toxic Optic Neuropathy UI - D000081028 MN - C10.292.200.750.500 MN - C10.292.700.475.500 MN - C10.900.300.218.550.500 MN - C11.640.530.500 MN - C23.550.877 MN - C25.100.937 MN - C26.733.902 MN - G1.750.748.500.902 MS - Damage to the eye or its function (e.g., VISUAL IMPAIRMENT) due to OPTIC NERVE damage secondary to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION. HN - 2020 BX - Ocular Toxicity MH - Trichothecenes, Type A UI - D000080505 MN - D2.455.849.765.850.950 MN - D4.345.891.950 MN - D23.946.587.933.950 MS - A subclass of Trichothecene derivatives that include the 12,13-epoxytrichothec-9-ene structure of the molecule with the C-8 position containing either no oxygen substitution, a hydroxyl group at C-8, or an ester function at C-8. HN - 2020 BX - Type A Trichothecenes MH - Trichothecenes, Type B UI - D000081442 MN - D2.455.849.765.850.975 MN - D4.345.891.963 MN - D23.946.587.933.975 MS - A subclass of Trichothecene derivatives that include the 12,13-epoxytrichothec-9-ene structure with a keto (carbonyl) function at C-8. HN - 2020 BX - Type B Trichothecenes MH - Trichothecenes, Type C UI - D000081443 MN - D2.455.849.765.850.987 MN - D4.345.891.975 MN - D23.946.587.933.987 MS - A subclass of Trichothecene derivatives that includes the 12,13-epoxytrichothec-9-ene structure with an epoxide oxygen bond to the C7 and C8 carbon atoms. HN - 2020 BX - Type C Trichothecenes MH - Tumor Necrosis Factor Inhibitors UI - D000079424 MN - D27.505.954.158.757 MS - Compounds or agents that bind to and inhibit the synthesis or activity of TUMOR NECROSIS FACTOR-alpha. Such agents are used to treat inflammatory bowel diseases and other inflammatory diseases. HN - 2020 MH - Twinning, Dizygotic UI - D000080534 MN - G8.686.784.170.104.625.500 MS - The development of two genetically distinct EMBRYOS in a single UTERUS at the same time, from two separate OVA fertilized by two separate SPERMATOZOA. HN - 2020 BX - Dizygotic Twinning BX - Dizygous Twinning MH - Twinning, Embryonic UI - D000080530 MN - G8.686.784.170.104.625 MS - The development of two EMBRYOS in a single UTERUS at the same time. HN - 2020 BX - Embryo Twinning BX - Embryonic Twinning BX - Twinning, Embryo MH - Undiagnosed Diseases UI - D000080842 MN - C23.550.291.968 MS - Rare and common diseases lacking a diagnosis. HN - 2020 FX - Delayed Diagnosis MH - Univentricular Heart UI - D000080039 MN - C14.240.400.990 MN - C14.280.400.990 MN - C16.131.240.400.975 MS - Rare congenital heart malformation with a single ventricle (HEART VENTRICLES) instead of the usual two. HN - 2020 BX - Complex Single Ventricle MH - Universal Design UI - D000080562 MN - I1.880.709.359.500 MN - J1.86.669 MN - J1.293.910 MS - The design of products and environments to be usable by all people, to the greatest extent possible, without the need for adaption or specialized design. HN - 2020 BX - Design for All BX - Human Centered Design MH - Universal Health Care UI - D000080423 MN - N3.706.871 MN - N4.590.374.350.875 MN - N4.940 MS - Access for all people to needed health services (including prevention, promotion, treatment, rehabilitation and palliation) of sufficient quality to be effective while also ensuring that the use of these services does not expose the user to financial hardship. (From https://www.who.int/healthsystems/universal_health_coverage/en/) HN - 2020 BX - Universal Healthcare MH - Uveal Effusion Syndrome UI - D000080323 MN - C11.250.105.500 MN - C11.941.160.241.500 MS - Rare disease characterized by suprachoroidal fluid accumulation between the CHOROID and the SCLERA, annular detachment of the CHOROID, often with secondary RETINAL DETACHMENT; OPTIC DISK EDEMA, and minimal signs of UVEITIS and INTRAOCULAR PRESSURE changes. HN - 2020 MH - Vaccine Excipients UI - D000079282 MN - D26.650.800 MN - D27.720.744.770.419.500 MS - Media added to a vaccine for a specific purpose. These include: preservatives to prevent contamination, adjuvants to stimulate a stronger immune response, and stabilizers. (From https://www.cdc.gov/vaccines pubs/pinkbook/downloads/appendices/b/excipient-table-2.pdf) HN - 2020 MH - Vaccine-Preventable Diseases UI - D000079263 MN - C1.918 MS - Diseases for which vaccines exist that can confer partial or complete protection. (World Health Organization vaccine-safety-training.org) HN - 2020 MH - Vector Borne Diseases UI - D000079426 MN - C1.920 MS - Infectious diseases transmitted by DISEASE VECTORS. AN - general or unspecified; prefer specifics HN - 2020 MH - Veterans Health Services UI - D000081324 MN - N2.421.917 MN - N4.452.524 MS - Services organized for the diagnosis and treatment of diseases and maintenance of health primarily of VETERANS. HN - 2020 MH - WAP Four-Disulfide Core Domain Protein 2 UI - D000081102 MN - D12.776.298.500 MS - A secreted 25-kDa glycoprotein member of the Whey-acidic-protein (WAP) four-disulfide core (WFDC) domain family with tissue specific expression in the EPIDIDYMIS. It is also expressed in a limited number of other organs which include female reproductive tract, breast tissue, kidney, regions of the respiratory tract and nasopharynx. The protein is a biomarker for epithelial ovarian cancer. HN - 2020 BX - Epididymal Secretory Protein E4 BX - WFDC2 Protein MH - Wastewater-Based Epidemiological Monitoring UI - D000079686 MN - E5.318.375.500 MN - N6.850.520.460.500 MS - Sampling of the liquids generated from industrial processes, sanitary fixtures and appliances, food handling, etc., to collect and analyze epidemiological information (such as pathogen levels, or concentrations of pesticides, pharmaceuticals, or other substances) from metabolic excretion products, household liquid wastes, and industrial wastes. HN - 2020 BX - Sewage-Based Epidemiology BX - Wastewater-Based Epidemiology FX - Biological Monitoring FX - Environmental Monitoring MH - Water Decolorization UI - D000080868 MN - N6.850.780.200.800.800.900.900.500 MN - N6.850.860.510.900.900.500 MS - The removal of DYES; STAINS; or other COLORING AGENTS, natural or synthetic, from water sources by various processes such as ADSORPTION; BIOREMEDIATION; enzymatic digestion; and ELECTROLYSIS. HN - 2020 BX - Waste Water Decolorization BX - Wastewater Decolorization FX - Coloring Agents MH - Weight Prejudice UI - D000079322 MN - F1.145.813.550.813 MN - F1.829.595.813 MS - Negative attitudes towards and beliefs about others because of their weight. These negative attitudes are manifested by stereotypes and/or prejudice towards people with weight over or under a cultural norm. HN - 2020 MH - White Dot Syndromes UI - D000080363 MN - C11.941.879.780.900.650 MS - A group of idiopathic multifocal posterior uveitis syndromes involving the CHOROID; RETINAL PIGMENT EPITHELIUM; and RETINA. They are characterized by multiple lesions of hypoautofluorescent dots in the FUNDUS OCULI and reduced VISUAL ACUITY. Several entities including BIRDSHOT CHORIORETINOPATHY are HLA-A ANTIGENS serotype A29 positive. HN - 2020 BX - Acute Idiopathic Blind Spot Enlargement Syndrome BX - Acute Macular Neuroretinopathy BX - Acute Posterior Multifocal Placoid Pigment Epitheliopathy BX - APMPPE BX - Diffuse Subretinal Fibrosis Uveitis BX - MEWDS BX - Multiple Evanescent White Dot Syndrome BX - Punctate Inner Choroidopathy BX - Serpiginous Choroiditis BX - Serpiginous Choroidopathy