NEW (2014) MESH HEADINGS WITH SCOPE NOTES (UNIT RECORD FORMAT; 7/29/2013) TOTAL 2014 NEW DESCRIPTORS = 304 MH - 3-Hydroxyacyl-CoA Dehydrogenase UI - D063988 MN - D8.811.682.47.820.150.207 MS - An NAD-dependent 3-hydroxyacyl CoA dehydrogenase that has broad specificity with regards to the acyl chain length of the substrate. HN - 2014; use 3-HYDROXYACYL COA DEHYDROGENASES 1981-2013 MH - 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase UI - D064431 MN - D8.811.682.47.820.196 MS - A 3-oxoacyl reductase that has specificity for ACYL CARRIER PROTEIN-derived FATTY ACIDS. HN - 2014 MH - 3-Phosphoinositide-Dependent Protein Kinases UI - D064413 MN - D8.811.913.696.620.682.700.745 MS - Highly conserved protein-serine threonine kinases that phosphorylate and activate a group of AGC protein kinases, especially in response to the production of the SECOND MESSENGERS, phosphatidylinositol 3,4,-biphosphate (PtdIns(3,4)P2) and phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3). HN - 2014 MH - Acceptance and Commitment Therapy UI - D064869 MN - F4.754.137.428.249 MS - Contextually focused form of cognitive behavioral psychotherapy that uses MINDFULNESS and behavioral activation to increase patients' psychological flexibility in areas such as ability to engage in values-based, positive behaviors while experiencing difficult thoughts, emotions, or sensations. HN - 2014 MH - Aggregatibacter UI - D064206 MN - B3.440.450.600.224 MN - B3.660.250.550.170 MS - A genus of PASTEURELLACEAE. Members are nonmotile, Gram-negative, facultatively anaerobic rods or coccobacilli. Its members are X factor (HEMIN) independent and variably dependent on V factor (NAD). HN - 2014 MH - Aggregatibacter aphrophilus UI - D064207 MN - B3.440.450.600.224.750 MN - B3.660.250.550.170.750 MS - A species of Gram-negative, facultatively anaerobic spherical or rod-shaped bacteria indigenous to oral cavity and pharynx. It is associated with BACTERIAL ENDOCARDITIS; and MENINGITIS. AN - infection: coordinate IM with PASTEURELLACEAE INFECTIONS (IM) HN - 2014 MH - Aggregatibacter segnis UI - D064208 MN - B3.440.450.600.224.875 MN - B3.660.250.550.170.875 MS - A species of Gram-negative, facultatively anaerobic pleomorphic rod-shaped often filamentous bacteria in the genus of AGGREGATIBACTER found in the oral cavity. It is associated with DENTAL PLAQUE; and BACTERIAL ENDOCARDITIS. AN - infection: coordinate IM with PASTEURELLACEAE INFECTIONS (IM) HN - 2014 MH - Air Travel UI - D064870 MN - I3.883.209 MS - Aspects of health and disease related to air travel. It includes the physiologic and psychologic beneficial or adverse effects. HN - 2014; use TRAVEL 2013 FX - Aerospace Medicine FX - Jet Lag Syndrome MH - Alcohol Abstinence UI - D064829 MN - F1.145.317.134 MS - Non-consumption of ALCOHOLIC BEVERAGES. AN - TEMPERANCE is also available HN - 2014 MH - Allelopathy UI - D064089 MN - G16.24 MS - The process by which organisms release chemical compounds known as ALLELOCHEMICALS which influence the physiology, growth, survival, colonization, and reproductive activities of other species usually located nearby. HN - 2014 MH - Allografts UI - D064591 MN - A1.941.500 MS - Tissues, cells, or organs transplanted between genetically different individuals of the same species. HN - 2014 FX - Transplantation, Homologous MH - alpha7 Nicotinic Acetylcholine Receptor UI - D064569 MN - D12.776.157.530.400.400.100.500.500 MN - D12.776.543.550.425.500.100.500.500 MN - D12.776.543.585.400.500.100.500.500 MN - D12.776.543.750.51.687.500 MN - D12.776.543.750.720.360.550.500 MS - A member of the NICOTINIC ACETYLCHOLINE RECEPTOR subfamily of the LIGAND-GATED ION CHANNEL family. It consists entirely of pentameric α7 subunits expressed in the CNS, autonomic nervous system, vascular system, lymphocytes and spleen. HN - 2014 MH - Alveolar Bone Grafting UI - D064728 MN - E4.545.562.500 MN - E4.555.580.289.500 MN - E6.645.562.124 MS - Surgical procedure to add bone to the ALVEOLAR RIDGE in children born with a CLEFT LIP and a CLEFT PALATE. HN - 2014 MH - Ambulance Diversion UI - D064422 MN - N2.421.297.879.49 MS - The practice of redirecting ambulances and patients seeking urgent care from one emergency department to others for various reasons such as overcrowding and shortage of skilled staff. HN - 2014 MH - Ammonium Compounds UI - D064751 MN - D1.625.62 MS - Inorganic compounds that include a positively charged tetrahedral nitrogen (ammonium ion) as part of their structure. This class of compounds includes a broad variety of simple ammonium salts and derivatives. HN - 2014; use QUATERNARY AMMONIUM COMPOUNDS 2006-2013 MH - Ammonium Hydroxide UI - D064753 MN - D1.455.212 MN - D1.625.62.311 MS - The hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution. HN - 2014 FX - Ammonia MH - Anaphase-Promoting Complex-Cyclosome UI - D064173 MN - D8.811.464.938.750.92 MN - D12.776.167.24 MS - An E3 ubiquitin ligase primarily involved in regulation of the metaphase-to-anaphase transition during MITOSIS through ubiquitination of specific CELL CYCLE PROTEINS. Enzyme activity is tightly regulated through subunits and cofactors, which modulate activation, inhibition, and substrate specificity. The anaphase-promoting complex, or APC-C, is also involved in tissue differentiation in the PLACENTA, CRYSTALLINE LENS, and SKELETAL MUSCLE, and in regulation of postmitotic NEURONAL PLASTICITY and excitability. HN - 2014 MH - Ankle Fractures UI - D064386 MN - C26.404.14 HN - 2014 MH - Anticholinergic Syndrome UI - D064807 MN - C25.100.311 MS - Adverse drug effects associated with CHOLINERGIC ANTAGONISTS. Clinical features include TACHYCARDIA; HYPERTHERMIA; MYDRIASIS, dry skin and dry mucous membranes, decreased bowel sounds and urinary retention in peripheral anticholinergic syndrome; and HALLUCINATIONS; PSYCHOSES; SEIZURES; and COMA in central anticholinergic syndrome. HN - 2014 FX - Cholinergic Antagonists MH - Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome UI - D064189 MN - D8.811.464.938.750.92.500 MN - D12.776.167.24.500 MS - The largest subunit of the anaphase-promoting complex. It acts primarily as a scaffold for the proper organization and arrangement of subunits. The C-terminal region of Apc1 contains a series of tandem amino acid repeats that are also seen in the 26S proteasome regulatory particle, and may assist with forming and stabilizing protein-protein interactions. HN - 2014 MH - Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome UI - D064197 MN - D8.811.464.938.750.92.625 MN - D12.776.167.24.625 MS - Apc10 is necessary for coactivator-dependent substrate recognition by the anaphase-promoting complex-cyclosome. It binds the Apc2 subunit, which is a part of the catalytic core, and interacts with coactivators Cdh1 or Cdc20 to recruit substrates to the complex. HN - 2014 MH - Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome UI - D064198 MN - D8.811.464.938.750.92.687 MN - D12.776.167.24.687 MS - Together with the Apc2 subunit, forms the catalytic core of the E3 ubiquitin ligase, anaphase-promoting complex-cyclosome. It has a RING H2 domain which interacts with the cullin domain of Apc2. Apc11 also interacts with the E2 ubiquitin ligases involved in APC-C ubiquitination reactions. HN - 2014 MH - Apc2 Subunit, Anaphase-Promoting Complex-Cyclosome UI - D064190 MN - D8.811.464.938.750.92.750 MN - D12.776.167.24.750 MS - Together with the Apc11 subunit, forms the catalytic core of the E3 ubiquitin ligase anaphase-promoting complex (APC-C). Its N-terminus has cullin domains which associate with the RING FINGER DOMAINS of Apc11. Apc2 also interacts with the E2 ubiquitin ligases involved in APC-C ubiquitination reactions. HN - 2014 MH - Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome UI - D064191 MN - D8.811.464.938.750.92.875 MN - D12.776.167.24.875 MS - A highly evolutionarily conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. These domains, also found in Apc subunits 6, 7, and 8, have been shown to mediate protein-protein interactions, suggesting that Apc3 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to co-activators and APC-C inhibitors. HN - 2014 MH - Apc4 Subunit, Anaphase-Promoting Complex-Cyclosome UI - D064192 MN - D8.811.464.938.750.92.937 MN - D12.776.167.24.937 MS - A subunit of the anaphase-promoting complex whose primary function is to provide structural support for the catalytic and substrate-recognition modules of the complex. Apc4, along with Apc5, tethers the tetratricopeptide-coactivator binding subcomplex to the main structural subunit, Apc1. HN - 2014 MH - Apc5 Subunit, Anaphase-Promoting Complex-Cyclosome UI - D064193 MN - D8.811.464.938.750.92.968 MN - D12.776.167.24.968 MS - A subunit of the anaphase-promoting complex whose primary function is to provide structural support for the catalytic and substrate-recognition modules of the complex. Apc5, along with Apc4, tethers the tetratricopeptide-coactivator binding subcomplex to the main structural subunit, Apc1. HN - 2014 MH - Apc6 Subunit, Anaphase-Promoting Complex-Cyclosome UI - D064194 MN - D8.811.464.938.750.92.984 MN - D12.776.167.24.984 MS - A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34 amino acid tetratricopeptide repeats. These domains, also found in Apc3, Apc7, and Apc8, have been shown to mediate protein-protein interactions, suggesting that Apc6 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to coactivators and APC-C inhibitors. HN - 2014 MH - Apc7 Subunit, Anaphase-Promoting Complex-Cyclosome UI - D064195 MN - D8.811.464.938.750.92.992 MN - D12.776.167.24.992 MS - A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34 amino acid tetratricopeptide repeats. These domains, also found in Apc3, Apc6, and Apc8, have been shown to mediate protein-protein interactions, suggesting that Apc7 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to coactivators and APC-C inhibitors. HN - 2014 MH - Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome UI - D064196 MN - D8.811.464.938.750.92.996 MN - D12.776.167.24.996 MS - A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. These domains, also found in Apc3, Apc6, and Apc7, have been shown to mediate protein-protein interactions, suggesting that Apc8 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to coactivators and APC-C inhibitors. HN - 2014 MH - Apicoplasts UI - D063546 MN - A11.284.430.214.190.875.700.69 MS - Non-photosynthetic plastids derived from RED ALGAE endosymbionts. They are found in species of the phylum APICOMPLEXA including PLASMODIUM MALARAIAE. HN - 2014 MH - Asia, Northern UI - D064873 MN - Z1.252.122 MS - A subregion of Asia, consisting of the Asian portion of Russia. HN - 2014 MH - Ataxia Telangiectasia Mutated Proteins UI - D064007 MN - D8.811.913.696.620.682.700.97 MS - A group of PROTEIN-SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control. HN - 2014 MH - ATP Binding Cassette Transporter 1 UI - D064286 MN - D12.776.157.530.100.151 MN - D12.776.395.550.20.304 MN - D12.776.543.550.192.304 MN - D12.776.543.585.100.151 MS - A superfamily of large integral ATP-binding cassette membrane proteins whose expression pattern is consistent with a role in lipid (cholesterol) efflux. It is implicated in TANGIER DISEASE characterized by accumulation of cholesteryl ester in various tissues. HN - 2014 FX - Tangier Disease MH - Atrial Remodeling UI - D064752 MN - C23.300.52 MN - C23.550.113 MN - G9.330.190.75.800 MS - Long-term changes in the electrophysiological parameters and/or anatomical structures of the HEART ATRIA that result from prolonged changes in atrial rate, often associated with ATRIAL FIBRILLATION or long periods of intense EXERCISE. HN - 2014 MH - Aurora Kinase A UI - D064096 MN - D8.811.913.696.620.682.700.103.500 MN - D12.776.167.49.500 MS - An aurora kinase that localizes to the CENTROSOME during MITOSIS and is involved in centrosome regulation and formation of the MITOTIC SPINDLE. Aurora A overexpression in many malignant tumor types suggests that it may be directly involved in NEOPLASTIC CELL TRANSFORMATION. HN - 2014 BX - Aurora A Kinases BX - Aurora Kinases A MH - Aurora Kinase B UI - D064107 MN - D8.811.913.696.620.682.700.103.750 MN - D12.776.167.49.750 MS - An aurora kinase that is a component of the chromosomal passenger protein complex and is involved in the regulation of MITOSIS. It mediates proper CHROMOSOME SEGREGATION and contractile ring function during CYTOKINESIS. HN - 2014 BX - Aurora B Kinases BX - Aurora Kinases B MH - Aurora Kinase C UI - D064108 MN - D8.811.913.696.620.682.700.103.875 MN - D12.776.167.49.875 MS - Aurora kinase C is a chromosomal passenger protein that interacts with aurora kinase B in the regulation of MITOSIS. It is found primarily in GERM CELLS in the TESTIS, and may mediate CHROMOSOME SEGREGATION during SPERMATOGENESIS. HN - 2014 BX - Aurora C Kinases BX - Aurora Kinases C MH - Aurora Kinases UI - D064127 MN - D8.811.913.696.620.682.700.103 MN - D12.776.167.49 MS - A family of highly conserved serine-threonine kinases that are involved in the regulation of MITOSIS. They are involved in many aspects of cell division, including centrosome duplication, SPINDLE APPARATUS formation, chromosome alignment, attachment to the spindle, checkpoint activation, and CYTOKINESIS. HN - 2014 MH - Autografts UI - D064592 MN - A1.941.750 MS - Transplant comprised of an individual's own tissue, transferred from one part of the body to another. AN - use for the autograft itself; use AUTOGRAFTING see TRANSPLANTATION, AUTOLOGOUS for the surgical procedure HN - 2014 FX - Transplantation, Autologous MH - Back Muscles UI - D064131 MN - A2.633.567.175 AN - general or unspecified; prefer specifics HN - 2014 MH - Basal Bodies UI - D064652 MN - A11.284.430.214.190.750.585.79 MS - Structures which form the base of FLAGELLA and CILIA. They contain nine triplets of MICROTUBULES that are arranged around the periphery and that serve as the nucleation center for AXONEME assembly. HN - 2014 MH - Biodegradable Plastics UI - D063566 MN - D5.750.716.195 MN - D25.720.716.195 MN - J1.637.51.720.716.195 MS - Organic polymeric materials which can be broken down by naturally occurring processes. This includes plastics created from bio-based or petrochemical-based materials. HN - 2014 MH - Biological Ontologies UI - D064229 MN - L1.224.65.480.500 MN - L1.453.245.945.79 MN - L1.700.508.300.550.500 MS - Structured vocabularies describing concepts from the fields of biology and relationships between concepts. HN - 2014 MH - Bland White Garland Syndrome UI - D063748 MN - C14.240.400.210.249 MN - C14.240.850.984.500.500 MN - C14.280.400.210.249 MN - C14.907.933.110.500 MN - C16.131.240.400.210.249 MN - C16.131.240.850.500.500 MN - C23.300.575.950.150.500 MS - A congenital coronary vessel anomaly in which the left main CORONARY ARTERY originates from the PULMONARY ARTERY instead of from AORTA. The congenital heart defect typically results in coronary artery FISTULA; LEFT-SIDED HEART FAILURE and MITRAL VALVE INSUFFICIENCY during the first months of life. HN - 2014 MH - Bone-Patellar Tendon-Bone Grafts UI - D064594 MN - A1.941.812 MS - A bone-patellar tendon graft used for fixation of the ANTERIOR CRUCIATE LIGAMENT during surgical reconstruction of the knee. AN - use for the graft itself; use BONE-PATELLAR TENDON-BONE GRAFTING for the surgical procedure HN - 2014 MH - British Virgin Islands UI - D064966 MN - Z1.107.84.900.182 MS - A British overseas territory, part of the British West Indies, lying about 60 miles east of Puerto Rico. Tortola is the main island, other islands include Virgin Gorda, Jost Van Dyke and Anegada. HN - 2014; use WEST INDIES 1979-2013 BX - Virgin Islands, British MH - Bromochlorofluorocarbons UI - D064228 MN - D2.455.526.368.175 MN - D2.455.526.439.220.149 MN - D2.455.526.510.140.149 MS - A series of hydrocarbons containing BROMINE; CHLORINE and FLOURINE. HN - 2014 MH - Bunolol UI - D064805 MN - D2.33.100.624.698.115 MN - D2.33.755.624.698.115 MN - D2.92.63.624.698.115 MN - D2.455.426.559.847.638.960.446 MN - D4.615.638.960.446 MS - A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma. HN - 2014; use LEVOBUNOLOL 1991-2013 MH - Calbindin 1 UI - D064092 MN - D12.776.157.125.90.124 MN - D12.776.641.87 MS - A calcium-binding protein that mediates calcium HOMEOSTASIS in KIDNEYS, BRAIN, and other tissues. It is found in well-defined populations of NEURONS and is involved in CALCIUM SIGNALING and NEURONAL PLASTICITY. It is regulated in some tissues by VITAMIN D. HN - 2014 MH - Calbindin 2 UI - D064032 MN - D12.776.157.125.90.249 MS - A calbindin protein that is differentially expressed in distinct populations of NEURONS throughout the vertebrate and invertebrate NERVOUS SYSTEM, and modulates intrinsic neuronal excitability and influences LONG-TERM POTENTIATION. It is also found in LUNG, TESTIS, OVARY, KIDNEY, and BREAST, and is expressed in many tumor types found in these tissues. It is often used as an immunohistochemical marker for MESOTHELIOMA. HN - 2014 BX - Calretinin MH - Calbindins UI - D064026 MN - D12.776.157.125.90 MS - Calcium-binding proteins that are found in DISTAL KIDNEY TUBULES, INTESTINES, BRAIN, and other tissues where they bind, buffer and transport cytoplasmic calcium. Calbindins possess a variable number of EF-HAND MOTIFS which contain calcium-binding sites. Some isoforms are regulated by VITAMIN D. HN - 2014 FX - EF Hand Motifs MH - Carcinogenesis UI - D063646 MN - C4.697.98 MN - C23.550.727.98 MS - The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. HN - 2014; for TUMORIGENESIS and ONCOGENESIS see CELL TRANSFORMATION, NEOPLASTIC 2012-2013 BX - Tumorigenesis MH - Cardiovascular Nursing UI - D064646 MN - H2.478.676.112 MN - N2.421.533.99 MS - A specialty concerned with the nursing care of patients suffering from disorders of the CARDIOVASCULAR SYSTEM as well as those identified as at risk for adverse cardiac or vascular events. HN - 2014 MH - Cartilage Oligomeric Matrix Protein UI - D064236 MN - D12.776.860.300.155 MS - Major component of chondrocyte EXTRACELLULAR MATRIX of various tissues including bone, tendon, ligament, SYNOVIUM and blood vessels. It binds MATRILIN PROTEINS and is associated with development of cartilage and bone. HN - 2014 MH - Cdc20 Proteins UI - D064199 MN - D8.811.464.938.750.92.998 MN - D12.776.167.24.998 MN - D12.776.167.74 MS - Highly conserved proteins that specifically bind to and activate the anaphase-promoting complex-cyclosome, promoting ubiquitination and proteolysis of cell-cycle-regulatory proteins. Cdc20 is essential for anaphase-promoting complex activity, initiation of anaphase, and cyclin proteolysis during mitosis. HN - 2014 MH - Cdh1 Proteins UI - D064200 MN - D8.811.464.938.750.92.999 MN - D12.776.167.24.999 MN - D12.776.167.125 MS - Cdh1 is an activator of the anaphase-promoting complex-cyclosome, and is involved in substrate recognition. It associates with the complex in late MITOSIS from anaphase through G1 to regulate activity of CYCLIN-DEPENDENT KINASES and to prevent premature DNA replication. HN - 2014 MH - Cell- and Tissue-Based Therapy UI - D064987 MN - E2.95.147 MS - Therapies that involve the TRANSPLANTATION of CELLS or TISSUES developed for the purpose of restoring the function of diseased or dysfunctional cells or tissues. HN - 2014 BX - Cell Therapy BX - Tissue Therapy FX - Cell Engineering FX - Guided Tissue Regeneration FX - Regenerative Medicine FX - Tissue Engineering FX - Tissue Therapy, Historical MH - Cephalochordata UI - D064174 MN - B1.50.150.200.199 MN - B1.50.500.272.199 MS - A subphylum of chordates intermediate between the invertebrates and the true vertebrates. It includes the LANCELETS. Its members are characterized by a NOTOCHORD which extends into the adult stage head. HN - 2014 MH - Checkpoint Kinase 2 UI - D064447 MN - D8.811.913.696.620.682.700.145 MS - Enzyme activated in response to DNA DAMAGE involved in cell cycle arrest. The gene is located on the long (q) arm of chromosome 22 at position 12.1. In humans it is encoded by the CHEK2 gene. HN - 2014 MH - Chemically-Induced Disorders UI - D064419 MN - C25 MS - Disorders caused by the intentional or unintentional ingestion or exposure to chemical substances such as PHARMACEUTICAL PREPARATIONS; NOXAE; and PESTICIDES. AN - general or unspecified; prefer specifics HN - 2014 MH - Chemotherapy-Induced Febrile Neutropenia UI - D064146 MN - C15.378.553.546.184.564.750.500 MS - FEVER accompanied by a significant reduction in NEUTROPHIL count associated with CHEMOTHERAPY. HN - 2014 MH - Chlorofluorocarbons, Ethane UI - D064227 MN - D2.455.526.439.220.224 MN - D2.455.526.510.140.224 MS - A group of ethane-based halogenated hydrocarbons containing one or more fluorine and chlorine atoms. HN - 2014 MH - Clinical Laboratory Services UI - D064790 MN - N2.421.143.827.233.110 MN - N2.421.726.233.221 MS - Organized services provided by MEDICAL LABORATORY PERSONNEL for the purpose of carrying out CLINICAL LABORATORY TECHNIQUES used for the diagnosis, treatment, and prevention of disease. HN - 2014 FX - Clinical Laboratory Techniques FX - Laboratories MH - Clustered Regularly Interspaced Short Palindromic Repeats UI - D064112 MN - G2.111.570.80.708.800.325.500 MN - G5.360.80.708.800.325.500 MN - G5.360.340.24.850.69 MS - Repetitive nucleic acid sequences that are principal components of the archaeal and bacterial CRISPR-CAS SYSTEMS, which function as adaptive antiviral defense systems. HN - 2014 FX - CRISPR-Associated Proteins MH - Collagenous Sprue UI - D064068 MN - C6.405.469.637.378 MN - C18.452.603.314 MS - A malabsorption syndrome characterized by collagenous mucosal lesions of the SMALL INTESTINE, atrophy of MICROVILLI, severe malabsorption, diarrhea, and MALNUTRITION often refractory to a gluten-free diet. HN - 2014 MH - Composite Tissue Allografts UI - D064595 MN - A1.941.843 MS - A graft consisting of multiple tissues, such as muscle, bone, nerve, vasculature, and skin, comprising a functional unit for reconstructive purposes. AN - use for the graft itself; for COMPOSITE TISSUE ALLOGRAFTING see VASCULARIZED COMPOSITE ALLOTRANSPLANTATION for the surgical procedure HN - 2014 MH - Connectin UI - D064211 MN - D8.811.913.696.620.682.324 MN - D12.776.210.500.246 MS - A giant elastic protein of molecular mass ranging from 2,993 kDa (cardiac), 3,300 kDa (psoas), to 3,700 kDa (soleus) having a kinase domain. The amino- terminal is involved in a Z line binding, and the carboxy-terminal region is bound to the myosin filament with an overlap between the counter-connectin filaments at the M line. HN - 2014 MH - Cool-Down Exercise UI - D064590 MN - G11.427.590.530.698.277.124 MN - I3.350.124 MS - Tapering-off physical activity from vigorous to light, to gradually return the body to pre-exercise condition and metabolic state. HN - 2014 FX - Warm-Up Exercise MH - CRISPR-Associated Proteins UI - D064130 MN - D12.776.212 MS - Protein components of the CRISPR-CAS SYSTEMS for anti-viral defense in ARCHAEA and BACTERIA. These are proteins that carry out a variety of functions during the creation and expansion of the CRISPR ARRAYS, the capture of new CRISPR SPACERS, biogenesis of SMALL INTERFERING RNA (CRISPR or crRNAs), and the targeting and silencing of invading viruses and plasmids. They include DNA HELICASES; RNA-BINDING PROTEINS; ENDONUCLEASES; and RNA and DNA POLYMERASES. HN - 2014 FX - Clustered Regularly Interspaced Short Palindromic Repeats MH - CRISPR-Cas Systems UI - D064113 MN - G5.355.315.203.374.394 MS - Adaptive antiviral defense mechanisms, in archaea and bacteria, based on DNA repeat arrays called CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS (CRISPR elements) that function in conjunction with CRISPR-ASSOCIATED PROTEINS (Cas proteins). Several types have been distinguished, including Type I, Type II, and Type III, based on signature motifs of CRISPR-ASSOCIATED PROTEINS. HN - 2014 MH - Critical Care Nursing UI - D064648 MN - H2.478.676.175 MN - N2.421.533.149 MS - A nursing specialty that deals specifically with the care of patients who are critically ill. HN - 2014 MH - Dander UI - D063607 MN - A12.200.250 MS - Microscopic particles comprising dead skin, dried salivary proteins, hair, SEBUM and microorganisms, shed by animals which causes allergic reactions in atopic persons. HN - 2014 MH - Dandruff UI - D063807 MN - C17.800.174.146 MN - C17.800.738.353 MS - Excessive shedding of dry scaly material from the scalp in humans. HN - 2014 FX - Dermatitis, Seborrheic MH - Dataset UI - D064886 MN - V2.302 MS - An organized collection of values stored permanently in a formalized manner suitable for communication, interpretation, or processing. AN - this heading is used as a Publication Type HN - 2014 MH - Death-Associated Protein Kinases UI - D064550 MN - D8.811.913.696.620.682.700.125.387 MN - D12.644.360.100.387 MN - D12.776.476.100.387 MS - A family of calcium/calmodulin-dependent PROETIN-SERINE-THREONINE KINASES. They are ubiquitously expressed in adult and embryonic mammalian tissues, and their functions are tightly related to the early stages of eukaryotic programmed cell death. HN - 2014 MH - Delusional Parasitosis UI - D063726 MN - F3.700.356 MS - A delusional disorder of belief in infestation by insects or other parasites. This FORMICATION is typically accompanied by dermatological manifestation such as PRURITUS that may lead to self-mutilation in order to remove the perceived parasites. It can be either primary or secondary to a somatic or psychiatric condition. AN - note entry terms containing "Ekbom": do not confuse with entry terms for RESTLESS LEGS SYNDROME which also contain "Ekbom" HN - 2014; use Restless Legs Syndrome 2000-2013 FX - Morgellons Disease MH - Desoxycorticosterone Acetate UI - D064791 MN - D4.808.745.745.654.339.700 MN - D6.472.40.585.611.700 MS - The 21-acetate derivative of desoxycorticosterone. HN - 2014; for DESOXYCORTICOSTERONE ACETATE use DESOXYCORTICOSTERONE 2006-2013, BX - DOCA MH - Dexlansoprazole UI - D064748 MN - D2.886.640.74.249.500 MN - D3.383.725.24.249.500 MN - D3.438.103.34.249.500 MS - The R-isomer of lansoprazole. HN - 2014; use LANSOPRAZOLE 2008-2013 MH - Dexmethylphenidate UI - D064699 MN - D2.241.223.601.600.500 MN - D3.383.621.460.500 MS - The d-isomer of methylphenidate. HN - 2014; use METHYLPHENIDATE 2008-2013 MH - Dexrazoxane UI - D064730 MN - D3.383.606.385.500.500 MS - The (+)-enantiomorph of razoxane. HN - 2014 MH - Diagnostic Uses of Chemicals UI - D064907 MN - D27.505.259 MS - Chemicals administered to patients in order to diagnose or study the pathology of medical conditions, diseases, or syndromes. AN - used for searching: indexers and catalogers apply specifics HN - 2014 MH - Diapause, Insect UI - D064666 MN - G7.700.320.217 MS - Seasonal suspension of insect growth development. It can be either induced by environmental cues (e.g., PHOTOPERIOD) or as a facultative part of the life cycle in order to time development with seasonal changes. HN - 2014 MH - Diarylquinolines UI - D064687 MN - D3.438.810.87 MS - A class of quinoline compounds defined by the presence of two aromatic ring structures which are attached via a side chain to carbon 3 of the qunolinyl structure. The two aromatic moieties are typically NAPTHALENE and BENZENE. Several compounds in this class are used as ANTITUBERCULAR AGENTS. HN - 2014 MH - Disaster Victims UI - D064891 MN - M1.159 MS - Persons adversely effected by DISASTERS, occurrences that result in property damage, deaths, and/or injuries to a community. HN - 2014 MH - Dodecenoyl-CoA Isomerase UI - D064006 MN - D8.811.399.475.400.349 MS - A carbon-carbon double bond isomerase that catalyzes the movement double bond from C3 to C2 of an unsaturated acyl-CoA. The enzyme plays a key role in allowing acyl-CoA substrates to re-enter the beta-oxidation pathway. HN - 2014 MH - Drug Hypersensitivity Syndrome UI - D063926 MN - C17.800.174.600.262 MN - C20.543.206.380.262 MN - C25.100.468.380.262 MS - Severe drug eruption characterized by high fever, erythematous rash and inflammation of internal organ(s). HN - 2014 FX - Drug Hypersensitivity MH - Drug Trafficking UI - D064423 MN - I1.198.240.247 MN - I1.880.735.191.101 MS - The illegal acquisition, sale, production, transport, movement, and distribution of controlled substances such as narcotics. HN - 2014 MH - Drug-Related Side Effects and Adverse Reactions UI - D064420 MN - C25.100 MS - Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals. Note: for disorders relating to the abuse of drug see SUBSTANCE-RELATED DISORDERS. AN - general or unspecified only; prefer specific drug-related disorder + specific drug with /adv eff /pois or /tox HN - 2014; DRUG-TOXICITY was heading 1998-2013 FX - Clinical Trials, Phase IV as Topic FX - Drug Interactions MH - Dysbiosis UI - D064806 MN - C23.550.308 MS - Changes in quantitative and qualitative composition of MICROBIOTA. The changes may lead to altered host microbial interaction or homeostatic imbalance that can contribute to a disease state often with inflammation. HN - 2014 FX - Microbiological Phenomena MH - Ecological Parameter Monitoring UI - D064308 MN - E5.298 MS - Ongoing collection, analysis, and interpretation of ecological data that is used to assess changes in the components, processes, and overall condition and functioning of an ECOSYSTEM. HN - 2014 FX - Environmental Monitoring MH - Enclomiphene UI - D064695 MN - D2.455.426.559.389.150.700.125.500 MS - The trans or (E)-isomer of clomiphene. HN - 2014; use CLOMIPHENE 1992-2013 MH - Enoyl-CoA Hydratase 2 UI - D064008 MN - D8.811.520.241.300.275 MS - A PEROXISOME-specific enzyme that catalyzes the hydration step of the beta-oxidation pathway. HN - 2014 MH - Ependymoglial Cells UI - D063928 MN - A8.637.300 MN - A11.650.300 MS - The macroglial cells of EPENDYMA. They are characterized by bipolar cell body shape and processes that contact BASAL LAMINA around blood vessels and/or the PIA MATER and the CEREBRAL VENTRICLES. HN - 2014 FX - Ependyma FX - Ependymoma MH - Ethnic Conflict UI - D064868 MN - I1.880.735.304 MN - I1.880.735.900.575 MS - Violence or other hostile behavior arising when an ethnic group either feels itself under threat, or where it seeks to assert its superiority or dominance over other groups. HN - 2014 FX - Genocide MH - Etiolation UI - D064527 MN - G7.700.320.625.124 MN - G15.744.111 MS - Physical changes in the growth patterns of a plant brought on by sustained absence of light. These changes are characterized by lengthened internodes which produce long weak stems, fewer leaves, and pale yellow color (chlorosis). The physiological basis for etiolation is induction of the phytohormone, AUXIN. HN - 2014 MH - Family Nurse Practitioners UI - D064703 MN - M1.526.485.650.640.249 MN - N2.360.650.640.249 MS - Registered nurses with graduate degrees in nursing who provide care to patients of all age levels, and who focus their efforts on the health care needs of the entire family. HN - 2014 MH - Fatty Acid Synthases UI - D064429 MN - D8.811.277.352.897.387 MN - D8.811.520.241.300.287 MN - D8.811.682.47.820.196.500 MN - D8.811.913.50.134.29.500 MN - D8.811.913.50.170.500 MS - Enzymes that catalyze the synthesis of FATTY ACIDS from acetyl-CoA and malonyl-CoA derivatives. HN - 2014 MH - Febrile Neutropenia UI - D064147 MN - C15.378.553.546.184.564.750 MS - Fever accompanied by a significant reduction in the number of NEUTROPHILS. HN - 2014 MH - Fetal Alcohol Spectrum Disorders UI - D063647 MN - C13.703.277.220 MN - C16.300.70 MN - C25.775.100.87.323 MS - An umbrella term used to describe a pattern of disabilities and abnormalities that result from fetal exposure to ETHANOL during pregnancy. It encompasses a phenotypic range that can vary greatly between individuals, but reliably includes one or more of the following: characteristic facial dysmorphism, FETAL GROWTH RETARDATION, central nervous system abnormalities, cognitive and/or behavioral dysfunction, BIRTH DEFECTS. The level of maternal alcohol consumption does not necessarily correlate directly with disease severity. HN - 2014 FX - Alcoholism MH - Filamins UI - D064448 MN - A11.284.430.214.190.750.50.414 MN - D5.750.78.730.315 MN - D12.776.210.249 MN - D12.776.220.525.315 MS - A family of crosslinking filament proteins encoded by distinct FLN genes. Filamins are involved in cell adhesion, spreading, and migration, acting as scaffolds for over 90 binding partners including channels, receptors, intracellular signaling molecules and transcription factors. Due to the range of molecular interactions, mutations in FLN genes result in anomalies with moderate to lethal consequences. HN - 2014 MH - Gasotransmitters UI - D064426 MN - D1.362.282 MN - D27.505.519.625.270 MS - Endogenously produced lipid-soluble gaseous molecules which function as neurotransmitters and signal mediators targeting ION CHANNELS and transporters. HN - 2014 FX - Signal Transduction MH - Geminin UI - D064248 MN - D12.776.167.265 MS - Geminin inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex. It is absent during G1 phase of the CELL CYCLE and accumulates through S, G2,and M phases. It is degraded at the metaphase-anaphase transition by the ANAPHASE-PROMOTING COMPLEX-CYCLOSOME. HN - 2014 MH - Gene Ontology UI - D063990 MN - H1.158.273.343.249.99 MN - H1.770.644.145.350.124 MN - L1.224.65.480.500.500 MN - L1.453.245.945.79.500 MN - L1.700.508.300.550.500.500 MS - Sets of structured vocabularies used for describing and categorizing genes, and gene products by their molecular function, involvement in biological processes, and cellular location. These vocabularies and their associations to genes and gene products (Gene Ontology annotations) are generated and curated by the Gene Ontology Consortium. HN - 2014 MH - Genes, Microbial UI - D064351 MN - G5.360.340.24.340.364 MN - G5.360.340.358.24 MS - The functional hereditary units of a microorganism. AN - general or unspecified; prefer specifics HN - 2014 MH - Genome, Microbial UI - D064349 MN - G5.360.340.358 MS - The genetic complement of a microorganism as represented in its DNA or in some microorganisms its RNA. AN - general or unspecified; prefer specifics HN - 2014 FX - Genetics, Microbial MH - Hand Sanitizers UI - D064548 MN - D27.505.954.122.187.500 MN - D27.505.954.122.425.650 MN - D27.720.274.650 MS - Preparations used as alternatives or supplements to hand washing with soap and water to destroy microorganisms and prevent transmission of pathogens. The active ingredient may be ETHANOL; 1-PROPANOL; or POVIDONE-IODINE in a gel, foam, or liquid solution. HN - 2014 FX - Hand Disinfection MH - Hand Transplantation UI - D063987 MN - E4.936.450.825.500 MS - The transference of a complete HAND, as a composite of many tissue types, from one individual to another. HN - 2014 MH - Hazard Analysis and Critical Control Points UI - D064088 MN - J1.576.423.850.730.500.750 MN - N4.452.884.249 MN - N6.850.135.60.75.299 MN - N6.850.601.500.750 MS - A system of safety management (abbreviated HACCP) applied mainly to the food industry. It involves the analysis and control of biological, chemical, and physical hazards, from raw material production, procurement and handling, to manufacturing, distribution and consumption of finished products. HN - 2014 FX - Chemical Safety FX - Food Safety MH - Hazardous Waste Sites UI - D064371 MN - N6.850.780.200.800.800.900.449.500 MN - N6.850.860.510.900.700.500 MS - Sites where HAZARDOUS SUBSTANCES are deposited. Some have facilities for safely storing, processing, and recycling these waste products. AN - specify geographic location if pertinent HN - 2014 MH - Head Impulse Test UI - D064087 MN - E1.370.382.900.640 MS - Identification of SACCADES during a rapid head rotation to assess VESTIBULOOCULAR REFLEX. HN - 2014 MH - Healthy Volunteers UI - D064368 MN - M1.774.500 MN - M1.955.236 MS - Persons with no known significant health problems who are recruited to participate in research to test a new drug, device, or intervention as controls for a patient group. (from http://clinicalcenter.nih.gov/recruit/volunteers.html, accessed 2/14/2013) HN - 2014 MH - Hepcidins UI - D064451 MN - D12.776.494.249 MN - D12.776.543.695.54.425 MS - Forms of hepcidin, a cationic amphipathic peptide synthesized in the liver as a prepropeptide which is first processed into prohepcidin and then into the biologically active hepcidin forms, including in human the 20-, 22-, and 25-amino acid residue peptide forms. Hepcidin acts as a homeostatic regulators of iron metabolism and also possesses antimicrobial activity. HN - 2014 FX - Anemia FX - Hemochromatosis MH - Herbals as Topic UI - D064425 MN - L1.178.682.192.836.642 MS - Works about books, articles or other publications on herbs or plants describing their medicinal value. AN - do not confuse with the Publication Type HERBALS HN - 2014 MH - Heterografts UI - D064593 MN - A1.941.875 MS - Tissues, cells or organs transplanted between animals of different species. AN - use for the heterograft itself; use HETEROGRAFTING see TRANSPLANTATION, HETEROLOGOUS for the surgical procedure HN - 2014 FX - Transplantation, Heterologous MH - Histocompatibility Antigen H-2D UI - D064532 MN - D23.50.301.500.100.375 MS - A component of the murine major histocompatibilty complex class I family. It contains one Ig-like C1-type domain and functions in processing and presentation of exogenous peptide antigens to the immune system. HN - 2014 BX - Histocompatibility Antigen H-2D(b) MH - Home Health Nursing UI - D064650 MN - H2.478.676.150.500 MN - N2.421.143.150.500 MN - N2.421.143.524.419 MN - N2.421.539.89.500 MS - A nursing specialty in which skilled nursing care is provided to patients in their homes by registered or licensed practical NURSES. Home health nursing differs from HOME NURSING in that home health nurses are licensed professionals, while home nursing involves non-professional caregivers. HN - 2014 MH - Hope UI - D065026 MN - F1.470.572 MS - Belief in a positive outcome. AN - use only in the context of a mental process (for example, hope as a motivation for recovery, but not hope for increased research funding) HN - 2014 MH - Hospice and Palliative Care Nursing UI - D064946 MN - H2.478.676.350 MN - N2.421.533.390 MS - A nursing specialty concerned with care of patients facing serious or life-threatening illnesses.The goal of palliative nursing is to prevent and relieve suffering, and to support the best possible quality of life for patients and their families. Hospice nursing is palliative care for people in their final weeks or months of life. HN - 2014 BX - Palliative Care Nursing FX - Hospice Care FX - Palliative Care MH - Hospital Medicine UI - D064416 MN - H2.403.377 MS - The branch of medicine concerned with the delivery of comprehensive medical care to hospitalized patients. Practitioners include physicians and non-physician providers who engage in clinical care, teaching, research, or leadership in the field of general hospital medicine.(from http://www.hospitalmedicine.org/AM/Template.cfm?Section=Hospitalist_Definition) AN - use for the specialty only HN - 2014 FX - Hospitalists MH - Human Coprophagia UI - D064106 MN - F1.145.126.900 MS - A rare aberrant human behavior involving consumption of excrement. AN - COPROPHAGIA is available for animals HN - 2014(2013) BX - Human Coprophagy MH - Human Trafficking UI - D064410 MN - I1.198.240.748.470 MN - I1.880.735.384.399 MS - Recruitment, transportation, transfer, harbouring or receipt of persons, by means of the threat or use of force or other forms of coercion, of abduction, of fraud, of deception, of the abuse of power or of a position of vulnerability or of the giving or receiving of payments or benefits to achieve the consent of a person having control over another person, for the purpose of exploitation. (UN. Protocol to prevent, suppress and punish trafficking in persons, especially women and children, supplementing the United Nations convention against transnational organized crime. General Assembly resolution 55/25. United Nations General Assembly, 2000) HN - 2014 FX - Organ Trafficking MH - Hyoscyamine UI - D064692 MN - D2.145.74.722.229.199.500 MN - D3.132.760.180.572.199.500 MN - D3.132.889.180.648.199.500 MN - D3.605.869.229.199.500 MN - D4.75.80.875.99.722.229.199.500 MS - The 3(S)-endo isomer of atropine. HN - 2014; use ATROPINE 1976-2013; use BELLADONNA 1963-1974 BX - Atropine Sulfate, 3(S)-endo-Isomer BX - Hyoscyamine Sulfate MH - Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels UI - D064428 MN - D12.776.157.530.400.368 MN - D12.776.543.550.425.476 MN - D12.776.543.585.400.476 MS - A subgroup of cyclic nucleotide-regulated ION CHANNELS of the superfamily of pore-loop cation channels that are opened by hyperpolarization rather than depolarization. The ion conducting pore passes SODIUM, CALCIUM, and POTASSIUM cations with a preference for potassium. HN - 2014 BX - Hyperpolarization Cyclic-Nucleotide Gated Ion Channels MH - Hypertriglyceridemic Waist UI - D064250 MN - C18.452.584.500.500.851.875 MN - C23.888.521 MS - A screening phenotype consisting of both elevated WAIST CIRCUMFERENCE and elevated fasting TRIGLYCERIDES level. HN - 2014 FX - Lipid Accumulation Product MH - Hypoxia-Inducible Factor-Proline Dioxygenases UI - D064799 MN - D8.811.682.690.416.617.500 MN - D8.811.682.690.708.694.500 MS - Dioxygenase enzymes that specifically hydroxylate a PROLINE residue on the HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. They are OXYGEN-dependent enzymes that play an important role in mediating cellular adaptive responses to HYPOXIA. HN - 2014 MH - Identity Theft UI - D063867 MN - I1.198.240.300.249 MS - All types of crime in which personal data is obtained wrongfully, typically for economic gain.(from www.justice.gov/criminal/fraud/websites/idtheft.html) HN - 2014 MH - Immunity, Heterologous UI - D064789 MN - G12.450.418 MS - The immunological phenomenon by which exposure to some organisms or vaccines can profoundly alter the host's response to subsequent exposure to unrelated (heterologous) organisms or vaccines. HN - 2014 BX - Heterologous Immunity FX - Cross Protection FX - Cross Reactions MH - Influenza A Virus, H7N9 Subtype UI - D064766 MN - B4.820.545.405.400.800 MN - B4.909.777.545.405.400.800 MS - A subtype of INFLUENZA A VIRUS with the surface proteins hemagglutinin 7 and neuraminidase 9. This avian origin virus was first identified in humans in 2013. AN - infection: coordinate IM with INFLUENZA, HUMAN (IM) in humans, or INFLUENZA IN BIRDS (IM) in birds, or ORTHOMYXOVIRIDAE INFECTIONS (IM) in other animals HN - 2014 MH - Influenza Pandemic, 1918-1919 UI - D064149 MN - K1.400.504.968.450 MS - The influenza outbreaks of 1918 to 1919 also known as Spanish flu pandemic. First reported in Haskell County in Kansas in March of 1918 the disease spread throughout the world and may have killed as many as 25 million people. HN - 2014 FX - Influenza A Virus, H1N1 Subtype FX - Influenza, Human MH - Interleukin-27 UI - D064094 MN - D12.644.276.374.465.800 MN - D12.776.467.374.465.800 MN - D23.529.374.465.600 MS - A heterodimeric cytokine composed of the IL-27p28 and EBI3 subunits. It is produced primarily by antigen-presenting cells after stimulation by microbial products or inflammatory mediators. HN - 2014; use INTERLEUKIN-17 2007-2013 MH - Intermediate Back Muscles UI - D064169 MN - A2.633.567.175.500 MS - Two muscles, the serratus posterior superior and serratus posterior inferior, located in between the deep and the superficial back muscle layers. Their function is to control THORAX movement. HN - 2014 MH - International Classification of Functioning, Disability and Health UI - D064702 MN - L1.453.245.945.450 MS - The World Health Organization's classification categories of health and health-related domains. The International Classification of Functioning, Disability and Health (ICF) consists of two lists: a list of body functions and structure, and a list of domains of activity and participation.The ICF also includes a list of environmental factors. AN - CATALOG: use NAF entry HN - 2014 FX - Disability Evaluation MH - Intraocular Lymphoma UI - D064090 MN - C4.557.386.435 MN - C4.588.364.447 MN - C15.604.515.569.417 MN - C20.683.515.761.417 MS - A form of malignant cancer which occurs within the eyeball. HN - 2014 MH - Intraoperative Neurophysiological Monitoring UI - D064795 MN - E1.370.520.510.500 MN - E1.370.520.596.500 MN - E4.510.500 MS - The systematic checking of the condition and function of a patient's CENTRAL NERVOUS SYSTEM during the course of a surgical operation. HN - 2014 MH - Intrinsically Disordered Proteins UI - D064267 MN - D12.776.481 MS - Functional proteins that do not have unique, stable, folded, three-dimensional native structures or that possess non-ordered regions under physiological conditions. They are characterized by extraordinary structural flexibility and plasticity, which enable them to adopt different conformations in response to different stimuli or different interactions. HN - 2014 FX - Protein Folding FX - Protein Unfolding MH - Isografts UI - D064596 MN - A1.941.937 MS - Tissues, cells or organs transplanted between genetically identical individuals, i.e. members of the same species with identical histocompatibility antigens, such as monozygotic twins, members of the same inbred strain, or members of a hybrid population produced by crossing certain inbred strains. AN - use for the isograft itself; use ISOGRAFTING see TRANSPLANTATION, ISOGENEIC for the surgical procedure HN - 2014 FX - Transplantation, Isogeneic MH - Kosovo UI - D063826 MN - Z1.542.248.506 MS - Independence from SERBIA was declared on February 17, 2008. HN - 2014; use Yugoslavia 1994-2013 MH - Lancelets UI - D064175 MN - B1.50.150.200.199.500 MN - B1.50.500.272.199.500 MS - Small fish-like marine creatures often used in phylogenetic comparative studies of CHORDATES. HN - 2014 MH - Lansoprazole UI - D064747 MN - D2.886.640.74.249 MN - D3.383.725.24.249 MN - D3.438.103.34.249 MS - A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers. HN - 2014 BX - Lansoprazoles MH - Levalbuterol UI - D064412 MN - D2.33.100.291.57.500 MN - D2.92.63.291.57.500 MN - D2.92.471.683.61.500 MS - The R-isomer of albuterol. HN - 2014; use ALBUTEROL 2001-2013 MH - Levofloxacin UI - D064704 MN - D3.438.810.835.322.500.500 MS - The L-isomer of Ofloxacin. HN - 2014; use OFLXOACIN 2000-2013 MH - Lipid Accumulation Product UI - D064237 MN - E1.370.600.115.100.160.560.500 MN - E5.41.124.160.875.500 MS - An index for for monitoring the accumulation of lipids based on the WAIST CIRCUMFERENCE measurement and the level of TRIGLYCERIDES circulating in the blood. HN - 2014 FX - Hypertriglyceridemic Waist MH - Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase UI - D063989 MN - D8.811.682.47.820.150.707 MS - An NAD-dependent 3-hydroxyacyl CoA dehydrogenase that has specificity for acyl chains containing 8 and 10 carbons. HN - 2014 MH - Lorajmine UI - D064794 MN - D3.132.436.681.77.324 MN - D3.438.473.402.681.77.324 MS - A monochloroacetyl derivative of ajmaline. It is a class Ia antiarrhythmic agent that is rapidly hydrolyzed to ajmaline by plasma and tissue esterases. HN - 2014; use AJMALINE 1973-2013 MH - Lujo virus UI - D063927 MN - B4.820.57.70.100.525 MN - B4.909.777.80.70.100.525 MS - A species of ARENAVIRUS, OLD WORLD that is the etiologic agent of acute febrile illness with hemorrhagic manifestations in Africa. AN - infection: coordinate IM with ARENAVIRIDAE INFECTIONS (IM) + HEMORRHAGIC FEVERS, VIRAL (IM) if pertinent HN - 2014 MH - Mad2 Proteins UI - D064246 MN - D12.776.167.313 MN - D12.776.660.526 MS - Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES. HN - 2014 MH - Material Safety Data Sheets UI - D063967 MN - N4.452.871.900.500 MN - N4.452.884.500 MN - N6.850.135.60.75.800.500 MS - Information or data used to ensure the safe handling and disposal of substances in the workplace. Such information includes physical properties (i.e. melting, boiling, flashing points), as well as data on toxicity, health effects, reactivity, storage, disposal, first-aid, protective equipment, and spill-handling procedures. HN - 2014 MH - Matrilin Proteins UI - D064235 MN - D12.776.860.300.700 MS - PROTEOGLYCANS-associated proteins that are major components of EXTRACELLULAR MATRIX of various tissues including CARTILAGE; and INTERVERTEBRAL DISC structures. They bind COLLAGEN fibers and contain protein domains that enable oligomer formation and interaction with other extracellular matrix proteins such as CARTILAGE OLIGOMERIC MATRIX PROTEIN. HN - 2014 MH - Mean Platelet Volume UI - D063847 MN - E1.370.225.625.625.392 MN - E5.200.625.625.392 MN - G4.325.500 MS - A measure of the size of PLATELETS. HN - 2014 MH - Medical Identity Theft UI - D063866 MN - I1.198.240.300.249.500 MS - Unauthorized access to personal information to obtain medical care or drugs, or to submit fraudulent billing for services. (from https://oig.hhs.gov/fraud/medical-id-theft/index.asp) HN - 2014 MH - Medical Marijuana UI - D064086 MN - D26.528 MS - Product of the CANNABIS plant, CANNABINOIDS, or synthetic derivatives thereof, used in the treatment of a wide range of clinical symptoms. HN - 2014 FX - Cannabis FX - Marijuana Smoking FX - Phytotherapy MH - MEF2 Transcription Factors UI - D064326 MN - D12.776.210.500.570.294 MN - D12.776.260.103.750.294 MN - D12.776.260.400.249.624 MN - D12.776.930.125.750.294 MN - D12.776.930.397.700 MS - Activating transcription factors of the MADS family which bind a specific sequence element (MEF2 element) in many muscle-specific genes and are involved in skeletal and cardiac myogenesis, neuronal differentiation and survival/apoptosis. HN - 2014 MH - Mesopotamia UI - D064867 MN - Z1.586.35.587 MS - Ancient land between the Tigris and Euphrates rivers, corresponding to modern-day Iraq and partly NE Syria, SE Turkey and smaller parts of SW Iran. It is considered to be the cradle of civilization in the West. Bronze Age Mesopotamia included Sumer and the Akkadian, Babylonian and Assyrian empires (from http://www.merriam-webster.com/dictionary/mesopotamia ) HN - 2014 MH - Metabolic Flux Analysis UI - D064688 MN - E1.370.225.500.810 MN - E5.242.654 MS - Measurement of cells' substrate utilization and biosynthetic output for modeling of METABOLIC NETWORKS. HN - 2014 FX - Metabolic Engineering MH - Methanocaldococcaceae UI - D063746 MN - B2.200.538.262 MS - A family of anaerobic METHANOCOCCALES whose organisms are thermophilic methanogens that produce methane from hydrogen and simple carbon sources such as carbon dioxide. HN - 2014 MH - Methanocaldococcus UI - D063747 MN - B2.200.538.262.500 MS - A genus of obligate anaerobic METHANOCALDOCOCCACEAE whose organisms are non-motile despite possessing long thin flagella. These methanogens are found in deep-sea vent and other hydrothermal environments. HN - 2014 MH - Microbiota UI - D064307 MN - G6.755 MN - G16.500.275.157.49.100.500 MN - N6.230.124.49.100.500 MS - The full collection of microbes (bacteria, fungi, virus, etc.) that naturally exist within a particular biological niche such as an organism, soil, a body of water, etc. AN - coordinate with specific organism, organ or other site with / microbiol if pertinent HN - 2014; use METAGENOME 2008-2013 BX - Human Microbiome BX - Microbiome BX - Microbiome, Human FX - Metagenome MH - Microscopy, Electrochemical, Scanning UI - D064347 MN - E1.370.350.515.666.450 MN - E5.595.666.450 MS - A scanning probe microscopy technique that uses an ultramicroelectrode as the scanning probe that simultaneously records changes in electrochemical potential as it scans thereby creating topographical images with localized electrochemical information. HN - 2014 MH - Mindfulness UI - D064866 MN - F2.463.551 MN - F4.754.137.428.500 MS - A psychological state of awareness, the practices that promote this awareness, a mode of processing information and a character trait. As a therapy mindfulness is defined as a moment-to-moment awareness of one's experience without judgment and as a state and not a trait. HN - 2014 MH - Minichromosome Maintenance Complex Component 2 UI - D064111 MN - D8.811.277.40.25.159.186.200 MN - D8.811.399.340.186.200 MN - D12.776.167.409.200 MN - D12.776.660.235.500.200 MN - D12.776.664.235.750.200 MS - A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It contains a NUCLEAR LOCALIZATION SIGNAL which may provide targeting of the protein complex and an extended N-terminus which is rich in SERINE residues. HN - 2014 MH - Minichromosome Maintenance Complex Component 3 UI - D064126 MN - D8.811.277.40.25.159.186.300 MN - D8.811.399.340.186.300 MN - D12.776.167.409.300 MN - D12.776.660.235.500.300 MN - D12.776.664.235.750.300 MS - A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It contains a NUCLEAR LOCALIZATION SIGNAL, which provide targeting of the protein complex. In addition, acetylation of this protein may play a role in regulating of DNA replication and cell cycle progression. HN - 2014 MH - Minichromosome Maintenance Complex Component 4 UI - D064148 MN - D8.811.277.40.25.159.186.400 MN - D8.811.399.340.186.400 MN - D12.776.167.409.400 MN - D12.776.660.235.500.400 MN - D12.776.664.235.750.400 MS - A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It is also found in tightly-bound trimeric complex with MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 6 and MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 7. HN - 2014 MH - Minichromosome Maintenance Complex Component 5 UI - D064150 MN - D8.811.277.40.25.159.186.500 MN - D8.811.399.340.186.500 MN - D12.776.167.409.500 MN - D12.776.660.235.500.500 MN - D12.776.664.235.750.500 MS - A minichromosome maintenance protein that is a key component of the six member MCM protein complex. In addition, interaction of this protein with cyclin A results in its recruitment to CENTROSOMES where it may play a role in controlling centrosome reduplication. HN - 2014 MH - Minichromosome Maintenance Complex Component 6 UI - D064151 MN - D8.811.277.40.25.159.186.600 MN - D8.811.399.340.186.600 MN - D12.776.167.409.600 MN - D12.776.660.235.500.600 MN - D12.776.664.235.750.600 MS - A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It is also found in tightly-bound trimeric complex with MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 4 and MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 7. HN - 2014 MH - Minichromosome Maintenance Complex Component 7 UI - D064168 MN - D8.811.277.40.25.159.186.700 MN - D8.811.399.340.186.700 MN - D12.776.167.409.700 MN - D12.776.660.235.500.700 MN - D12.776.664.235.750.700 MS - A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It is also found in tightly-bound trimeric complex with MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 4 and MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 6. HN - 2014 MH - Minichromosome Maintenance Complex Component 8 UI - D064187 MN - D8.811.277.40.25.159.186.800 MN - D8.811.399.340.186.800 MN - D12.776.167.409.800 MN - D12.776.660.235.500.800 MN - D12.776.664.235.750.800 MS - A minichromosome maintenance protein that forms a hexameric complex with MINICHROMSOME MAINTENANCE COMPLEX COMPONENT 9. The MCM8-MCM9 helicase complex is involved in HOMOLOGOUS RECOMBINATION REPAIR following the formation of DNA interstrand cross-links. HN - 2014 MH - Minichromosome Maintenance Complex Component 9 UI - D064188 MN - D8.811.277.40.25.159.186.900 MN - D8.811.399.340.186.900 MN - D12.776.167.409.900 MN - D12.776.660.235.500.900 MN - D12.776.664.235.750.900 MS - A minichromosome maintenance protein that forms a hexameric complex with MINICHROMSOME MAINTENANCE COMPLEX COMPONENT 8. The MCM8-MCM9 helicase complex is involved in HOMOLOGOUS RECOMBINATION REPAIR following the formation of DNA interstrand cross-links. HN - 2014 MH - Minichromosome Maintenance Proteins UI - D064110 MN - D8.811.277.40.25.159.186 MN - D8.811.399.340.186 MN - D12.776.167.409 MN - D12.776.660.235.500 MN - D12.776.664.235.750 MS - A family of proteins that were originally identified in SACCHAROMYCES CEREVISIAE as being essential for maintaining the structure of minichromosomes00. They form into a protein complex that has helicase activity and is involved in a variety of DNA-related functions including replication elongation, RNA transcription, chromatin remodeling, and genome stability. AN - general or unspecified; prefer specifics HN - 2014 MH - Mitochondrial Trifunctional Protein UI - D063991 MN - D8.811.520.241.300.250.249 MN - D8.811.641.765 MN - D8.811.682.47.820.150.707.249 MN - D8.811.913.50.80.249 MN - D12.776.543.602 MN - D12.776.575.765 MS - A mitochondrial protein consisting of four alpha-subunits and four beta-subunits. It contains enoyl-CoA hydratase, long-chain-3-hydroxyacyl-CoA dehydrogenase, and acetyl-CoA C-acyltransferase activities and plays an important role in the metabolism of long chain FATTY ACIDS. HN - 2014 MH - Mitochondrial Trifunctional Protein, alpha Subunit UI - D063992 MN - D8.811.520.241.300.250.249.500 MN - D8.811.641.765.200 MN - D8.811.682.47.820.150.707.249.500 MN - D12.776.543.602.200 MN - D12.776.575.765.200 MS - The alpha subunit of mitochondrial trifunctional protein. It contains both enoyl-CoA hydratase activity (EC 4.2.1.17) and long-chain-3-hydroxyacyl-CoA dehydrogenase activity (EC 1.1.1.211). There are four of these alpha subunits in each mitochondrial trifunctional protein molecule. HN - 2014 MH - Mitochondrial Trifunctional Protein, beta Subunit UI - D063993 MN - D8.811.641.765.500 MN - D8.811.913.50.80.249.500 MN - D12.776.543.602.500 MN - D12.776.575.765.500 MS - The beta subunit of mitochondrial trifunctional protein that contains acetyl-CoA C-acyltransferase activity. There are four of these beta subunits in each trifunctional protein complex. HN - 2014 MH - Mobile Applications UI - D063731 MN - L1.224.900.685 MS - Computer programs or software installed on mobile electronic devices which support a wide range of functions and uses which include television, telephone, video, music, word processing, and Internet service. HN - 2014 BX - Mobile Apps MH - Multifunctional Enzymes UI - D064251 MN - D8.811.641 MS - Molecules that contain multiple active sites which are used to catalyze more than one enzymatic reaction. Proteins in this class generally contain multiple active sites within a single peptide chain and may also contain more than one enzymatically active subunit. They are distinguished from MULTIENZYME COMPLEXES in that their subunits are not found as distinct enzymes. AN - MULTIENZYME COMPLEXES is also available HN - 2014 FX - Multienzyme Complexes MH - Multimodal Imaging UI - D064847 MN - E1.370.350.567 MS - The use of combination of imaging techniques or platforms (e.g., MRI SCAN and PET SCAN) encompassing aspects of anatomical, functional, or molecular imaging methods. AN - coordinate with specific imaging techniques used in combination HN - 2014 FX - Image Processing, Computer-Assisted MH - Myalgia UI - D063806 MN - C5.651.542 MN - C10.597.617.231.249 MN - C10.668.491.525 MN - F2.830.816.353.500 MN - G11.561.600.810.353.500 MS - Painful sensation in the muscles. HN - 2014 BX - Muscle Soreness MH - Myeloid Cell Leukemia Sequence 1 Protein UI - D064549 MN - D12.644.360.75.718.984 MN - D12.776.476.75.718.968 MN - D12.776.624.664.700.169.500 MS - A member of the myeloid leukemia factor (MLF) protein family with multiple alternatively spliced transcript variants encoding different protein isoforms. In hematopoietic cells, it is located mainly in the nucleus, and in non-hematopoietic cells, primarily in the cytoplasm with a punctate nuclear localization. MLF1 plays a role in cell cycle differentiation. HN - 2014 MH - Myocutaneous Flap UI - D064827 MN - A10.850.710.625 MN - E7.862.710.625 MS - A mass of tissue, including skin and muscle, that has been cut away from surrounding areas for transplantation. HN - 2014 MH - Myxovirus Resistance Proteins UI - D064547 MN - D8.811.277.40.330.300.550 MN - D12.776.157.325.636 MS - Interferon-induced DYNAMIN-like GTP-binding proteins localized in the cytoplasm, nuclear pore complex and nucleus. They play a role in antiviral defense and immunity. HN - 2014 MH - NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases UI - D064430 MN - D8.811.682.47.820 MS - Oxidoreductases that act on the CH-OH group of donors with NAD (+) or NADPH (+) as acceptors. HN - 2014 MH - National Longitudinal Study of Adolescent Health UI - D063588 MN - E5.318.760.500.750.500.500 MN - N5.715.360.775.175.250.450.500 MN - N6.850.520.450.500.750.500.500 MS - Longitudinal study of a nationally representative sample of adolescents in grades 7-12 in the United States during the 1994-95 school year. The Add Health cohort has been followed into young adulthood. (from http://www.cpc.unc.edu/projects/addhealth accessed 08/2012) AN - CATALOG: use NAF entry HN - 2014 MH - Nephrology Nursing UI - D064647 MN - H2.478.676.514 MN - N2.421.533.490 MS - A nursing specialty involving the care of patients with or at risk for KIDNEY DISEASES. HN - 2014 MH - Nestin UI - D064231 MN - D5.750.78.593.540 MN - D12.776.220.475.540 MN - D12.776.641.607 MS - A type VI intermediate filament protein expressed mostly in nerve cells where it is associated with the survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. HN - 2014 MH - Neurokinin-1 Receptor Antagonists UI - D064729 MN - D27.505.519.625.487 MN - D27.505.696.577.487 MS - Compounds that inhibit or block the activity of NEUROKININ-1 RECEPTORS. HN - 2014 MH - Neurophysiological Monitoring UI - D064926 MN - E1.370.520.596 MS - The systematic checking of the condition and function of a patient's CENTRAL NERVOUS SYSTEM during disease periods or following injuries, using various NEUROLOGICAL DIAGNOSTIC TECHNIQUES. HN - 2014 MH - Nocebo Effect UI - D064786 MN - N5.715.350.350.625.500 MN - N6.850.490.734.875.500 MS - An adverse effect occurring with a medical treatment that is not attributable to the actions of the treatment. AN - not restricted to drugs; IM general only HN - 2014 MH - Nodding Syndrome UI - D064128 MN - C10.228.140.490.375.525 MS - Unexplained neurologic condition characterized by episodes of atonic seizures, convulsions or staring spells with further cognitive decline. HN - 2014 MH - Non-Nutritive Sweeteners UI - D064306 MN - D27.720.364.609.500 MN - D27.720.888.500 MN - J2.500.512.400.700.500 MS - Chemical additives, such as aspartame, saccharin, and sucralose, that give a sweet taste to foods without contributing significant calories or promoting tooth decay. They are generally much sweeter than sucrose. HN - 2014 MH - Nurses, Community Health UI - D064691 MN - M1.526.485.650.655 MN - N2.360.650.655 MS - Nurses whose work combines elements of both primary care nursing and public health practice and takes place primarily outside the therapeutic institution. Primary nursing care is directed to individuals, families, or groups in their natural settings within communities. HN - 2014 BX - Health Visitors BX - Visiting Nurses MH - Nurses, International UI - D064700 MN - M1.526.407.717 MN - M1.526.485.650.662 MN - N2.360.650.662 MS - Nurses who provide nursing care in countries other than the ones in which they received their training. HN - 2014 MH - Nurses, Public Health UI - D064689 MN - M1.526.485.650.835 MN - N2.360.650.835 MS - Nurses whose goal is to improve health and quality of life in a population or community through the prevention and treatment of disease and other physical and mental health conditions, the surveillance of cases and health indicators, and the promotion of healthy behaviors through public education and awareness. HN - 2014 BX - Public Health Nurses MH - Nutritionists UI - D064686 MN - M1.526.485.67.676 MN - N2.360.67.676 MS - Persons specially trained in NUTRITION SCIENCES. HN - 2014 BX - Dieticians MH - Nutritive Sweeteners UI - D064427 MN - D27.720.364.609.750 MN - D27.720.888.750 MN - J2.500.512.400.700.750 MS - Any agent that adds not only sweet taste but some energy value to food. They include natural sugars such as SUCROSE; FRUCTOSE; and GALACTOSE; and certain SUGAR ALCOHOLS. HN - 2014 MH - O'nyong-nyong Virus UI - D064202 MN - B4.820.850.54.586 MN - B4.909.777.923.54.586 MS - A species of ALPHAVIRUS causing a measle-like acute febrile rash illness. It is closely related to the Chikungunya virus and Igbo Ora viruses. AN - infection: coordinate IM with ALPHAVIRUS INFECTIONS (IM) HN - 2014 BX - O'nyong'nyong Virus MH - Observational Study UI - D064888 MN - V3.200.650 MS - A clinical study in which participants may receive diagnostic, therapeutic, or other types of interventions, but the investigator does not assign participants to specific interventions (as in an interventional study). AN - this heading is used as a Publication Type; for original report of the conduct or results of a specific observational study; a different heading OBSERVATIONAL STUDIES AS TOPIC is used for general design, methodology, economics, etc. of observational studies HN - 2014 MH - Observational Study as Topic UI - D064887 MN - E5.318.760.535.750 MS - A clinical study in which participants may receive diagnostic, therapeutic, or other types of interventions, but the investigator does not assign participants to specific interventions (as in an interventional study). AN - for general design, methodology, economics, etc. of observational studies; a different heading OBSERVATIONAL STUDY is used for reports of a specific observational study HN - 2014 MH - Olfactometry UI - D064367 MN - E1.370.376.625 MN - E5.638 MS - Procedures for measuring a response to odorants. HN - 2014 FX - Olfactory Perception FX - Smell MH - Orexin Receptors UI - D064446 MN - D12.776.543.750.720.600.74 MN - D12.776.543.750.750.555.74 MS - G protein-coupled NEUROPEPTIDE RECEPTORS. These proteins have 7-transmembrane domains and are highly conserved across mammals, with 94% amino acid sequence overlap between humans and rats. Orexin-A and -B or hypocretin-1 and -2 neuropeptides produced in the lateral HYPOTHALAMUS promote arousal or wakefulness through orexin receptors. HN - 2014 MH - Organ Trafficking UI - D064877 MN - I1.880.735.191.152 MN - I1.880.735.384.599 MS - Criminal activity that occurs in three broad categories. Firstly, cases where traffickers force or deceive the victims into giving up an organ. Secondly, there are cases where victims formally or informally agree to sell an organ and are cheated because they are not paid for the organ or are paid less than the promised price. Thirdly, vulnerable persons are treated for an ailment, which may or may not exist and thereupon organs are removed without the victim's knowledge. HN - 2014 FX - Human Trafficking MH - Organogenesis, Plant UI - D063246 MN - G7.700.320.500.325.377.765 MN - G15.277 MS - Transformative processes which occur in cells and tissues to produce differentiated plant organs. HN - 2013 MH - Osmoregulation UI - D064587 MN - G2.111.635 MN - G3.615 MN - G7.700.345.810 MS - The response of cells in sensing a difference in OSMOTIC PRESSURE between the inside and outside of the cell. This response includes signaling from osmotic sensors to activate transcription factors, which in turn regulate the expression of osmocompensatory genes, all functioning to maintain CELL VOLUME and the water concentration inside the cells. HN - 2014; use WATER-ELECTROLYTE BALANCE 1975-2013 FX - Osmotic Pressure MH - Papanicolaou Test UI - D065006 MN - E1.370.225.500.384.100.422 MN - E1.370.225.998.54.422 MN - E4.74.422 MN - E5.200.500.384.100.422 MN - E5.200.998.54.422 MN - E5.242.384.100.422 MS - Cytological preparation of cells collected from a mucosal surface and stained with Papanicolaou stain. AN - coordinate with VAGINAL SMEARS if pertinent HN - 2014; use VAGINAL SMEARS 1991-2013 BX - Papanicolaou Smear MH - Paraspinal Muscles UI - D064170 MN - A2.633.567.175.750 MS - Deep muscles in the BACK whose function is to extend and rotate the SPINE and maintain POSTURE. It consists splenius, semispinalis, multifidus, rotatores, interspinales, intertransversarii and sacrospinalis. HN - 2014 MH - Parish Nursing UI - D064698 MN - H2.478.676.150.750 MN - N2.421.143.150.750 MS - A nursing specialty involving programs designed to bring wholeness and healing to a particular faith community through addressing the health needs of body, mind, and spirit. They are coordinated by registered NURSES and may involve HEALTH EDUCATION and counseling, facilitation, referral, PATIENT ADVOCACY, and health care plan interpretation, as influenced and defined by the unique needs of the congregation. HN - 2014 FX - Religion and Medicine MH - Patient Care Bundles UI - D064872 MN - E2.765 MS - Small sets of evidence-based interventions for a defined patient population and care setting. HN - 2014 BX - Care Bundles MH - Patient Discharge Summaries UI - D063886 MN - N4.452.859.564.725 MN - N5.715.360.300.715.500.665 MN - N6.850.520.308.940.968.750 MS - Summaries that serve as the primary documents communicating a patient's care plan to the post-hospital care team. HN - 2014 FX - Patient Discharge MH - Patient Harm UI - D064406 MN - N6.850.135.60.75.349 MN - N6.850.725 MS - A measure of PATIENT SAFETY considering errors or mistakes which result in harm to the patient. They include errors in the administration of drugs and other medications (MEDICATION ERRORS), errors in the performance of procedures or the use of other types of therapy, in the use of equipment, and in the interpretation of laboratory findings and preventable accidents involving patients. HN - 2014 MH - Patient Outcome Assessment UI - D063868 MN - N4.761.559.590.399 MN - N5.715.360.575.575.399 HN - 2014 MH - Pediatric Nurse Practitioners UI - D064701 MN - M1.526.485.650.640.500 MN - N2.360.650.640.500 MS - Registered nurses with graduate degrees in nursing who provide care to pediatric patients who are acutely or critically ill. HN - 2014 FX - Pediatric Assistants MH - Pediatric Obesity UI - D063766 MN - C18.654.726.500.720 MS - BODY MASS INDEX in children (ages 2-12) and adolescents (ages 13-18) that is grossly above the recommended cut-off for a specific age and sex. HN - 2014 BX - Childhood Obesity MH - Peripherins UI - D064531 MN - D5.750.78.593.765 MS - Type III intermediate filament proteins expressed mainly in neurons of the peripheral and CENTRAL NERVOUS SYSTEMS. Peripherins are implicated in neurite elongation during development and axonal regeneration after injury. HN - 2014 MH - Peroxisomal Bifunctional Enzyme UI - D063994 MN - D8.811.399.475.400.349.500 MN - D8.811.520.241.300.250.750 MN - D8.811.641.781 MN - D8.811.682.47.820.150.207.500 MS - A monomeric protein found in liver peroxisomes that contains two enzymatically active domains; an enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase domain, and an (S)-3-hydroxyacyl-CoA dehydrogenase domain. The enzyme is stereospecific with regards to how cis and trans double bonds are metabolized. It is complemented by PEROXISOMAL MULTIFUNCTIONAL PROTEIN-2, which has the opposite stereospecificity. HN - 2014 BX - Peroxisomal-Bifunctional Enzymes MH - Peroxisomal Multifunctional Protein-2 UI - D064029 MN - D8.811.520.241.300.275.500 MN - D8.811.641.812 MN - D8.811.682.47.436.375.640 MN - D8.811.682.47.820.150.926 MS - A dimeric protein found in liver peroxisomes that plays an important role in FATTY ACID metabolism and steroid metabolism. The dimer is formed by cleavage of a single protein precursor and contains an enoyl-CoA hydratase-2 domain and a second domain that displays (S)-3-hydroxyacyl-CoA dehydrogenase and 17-beta-estradiol dehydrogenase activities. The enzyme is stereospecific with regards to arrangement of the substrate double bonds and position of the 3-hydroxy group of the reaction intermediate. It is complemented by PEROXISOMAL BIFUNCTIONAL ENZYME, which has the opposite reaction stereospecificity. HN - 2014 MH - Pharmacy Residencies UI - D064172 MN - I2.358.525.741 MN - I2.358.750.500 MS - Advanced programs of training to meet certain professional requirements in the practice of compounding and dispensing medicinal preparations. HN - 2014 MH - Phospholipase A2 Inhibitors UI - D064801 MN - D27.505.519.389.737 MS - Compounds that inhibit or block the activity of a PHOSPHOLIPASE A2 enzyme. HN - 2014 MH - Physical Conditioning, Human UI - D064797 MN - G11.427.590.530.698.277.311 MN - I3.350.311 MS - Diet modification and physical exercise to improve the ability to carry out daily tasks and perform physical activities. HN - 2014; use PHYSICAL FITNESS (1997-2013); use EXERCISE THERAPY 1986-96 FX - Physical Conditioning, Animal FX - Sports Medicine MH - Phytochemicals UI - D064209 MN - D3.787 MN - D20.663 MS - A broad range of biologically active compounds which occur naturally in plants having important medicinal and nutritional properties. AN - general or unspecified; prefer specific chemical; note PLANT ALKALOIDS see ALKALOIDS is available HN - 2014 MH - Polypharmacology UI - D064798 MN - E5.295.500.500 MS - The design or use of pharmaceutical agents that act on multiple targets or disease pathways. AN - do not confuse with POLYPHARMACY, the use of multiple drugs administered to a single patient or with PHARMACOLOGY, the discipline HN - 2014 MH - Portion Size UI - D064787 MN - G7.610.240.835 MS - The amount of a particular food one chooses to eat at a single meal. It is different from SERVING SIZE, which is a reference amount of food as defined by an authoritative source, such as the Food Guide Pyramid devised by the UNITED STATES DEPARTMENT OF AGRICULTURE. AN - SERVING SIZE is also available HN - 2014 MH - Posterior Capsulotomy UI - D064727 MN - E4.540.825.784 MS - Procedures performed to remove CAPSULE OPACIFICATION that develops on the POSTERIOR CAPSULE OF THE LENS following removal of a primary CATARACT. HN - 2014 MH - Pragmatic Clinical Trial UI - D065007 MN - V3.200.700.500 MS - Randomized clinical trials that compare interventions in clinical settings and which look at a range of effectiveness outcomes and impacts. AN - this heading is used as a Publication Type; for original report of the conduct or results of a specific pragmatic clinical trial; a different heading PRAGMATIC CLINICAL TRIALS AS TOPIC is used for general design, methodology, economics, etc. of pragmatic clinical trials; use only when specified by author HN - 2014 MH - Pragmatic Clinical Trials as Topic UI - D064792 MN - E5.318.760.535.365.500.500 MN - E5.337.250.365.500.500 MN - N5.715.360.775.235.387.500.750 MN - N6.850.520.450.535.365.500.750 MS - Randomized clinical trials that compare interventions in clinical settings and which look at a range of effectiveness outcomes and impacts. AN - for general design, methodology, economics, etc. of pragmatic clinical trials; a different heading PRAGMATIC CLINICAL TRIAL is used for reports of a specific pragmatic clinical trial; use only when specified by author HN - 2014 BX - Pragmatic Clinical Trials FX - Comparative Effectiveness Research MH - Preexisting Condition Coverage UI - D064266 MN - N3.219.521.576.585.500 MS - Insurance coverage of a physical or mental health condition, disability, or illness existing before health insurance is applied for or enrolled in. AN - do not use for discussions of preexisting coverage associated with WORKERS' COMPENSATION HN - 2014 BX - Preexisting Condition MH - Prenatal Education UI - D064186 MN - I2.233.332.500.500 MN - N2.421.143.827.407.680.500 MN - N2.421.726.407.680.500 MS - Training for pregnant women and parents-to-be to prepare for CHILDBIRTH; CHILD CARE; and parenthood. HN - 2014 BX - Antenatal Education MH - Prescription Drug Diversion UI - D064226 MN - I1.198.240.609 MN - I1.880.735.191.204 MS - The transfer of prescription drugs from legal to illegal distribution and marketing networks. HN - 2014 FX - Inappropriate Prescribing FX - Prescription Drug Misuse FX - Street Drugs MH - Prisoners of War UI - D063906 MN - M1.729.500 MS - Members held prisoner of the armed forces, members of militias of such armed forces, members of other militias, members of other volunteer corps, and organized resistance movements. (Geneva Convention of 1929 and 1949) HN - 2014 MH - Prolyl Hydroxylases UI - D064828 MN - D8.811.682.690.416.617 MN - D8.811.682.690.708.694 MS - Enzymes that specifically hydroxylate PROLINE residues on proteins. HN - 2014; for PROLYL 4-HYDROXYLASE use PROCOLLAGEN-PROLINE DIOXYGENASE 1983-2013; for PEPTIDYL PROLYL HYDROXYLASE use PROCOLLAGEN-PROLINE DIOXYGENASE 1985-2013; for PROLINE,2-OXOGLUTARATE 4-DIOXYGENASE use PROCOLLAGEN-PROLINE DIOXYGENASE 1977-2013; for PROLINE HYDROXYLASE use PROCOLLAGEN-PROLINE DIOXYGENASE 1993-2013; for PROLYL HYDROXYLASE use PROCOLLAGEN-PROLINE DIOXYGENASE 1982-2013 BX - Proline Hydroxylase BX - Proline,2-Oxoglutarate 4-Dioxygenase MH - Prolyl-Hydroxylase Inhibitors UI - D064800 MN - D27.505.519.389.740 MS - Compounds that inhibit the action of HYDROXYLASES that act on PROLINE to form HYDROXYPROLINE. HN - 2014 MH - Prostatic Neoplasms, Castration-Resistant UI - D064129 MN - C4.588.945.440.770.500 MN - C12.294.260.750.500 MN - C12.294.565.625.500 MN - C12.758.409.750.500 MS - Tumors or cancer of the PROSTATE which can grow in the presence of low or residual amount of androgen hormones such as TESTOSTERONE. HN - 2014 FX - Androgen Receptor Antagonists MH - Protein Kinase C beta UI - D064546 MN - D8.811.913.696.620.682.700.725.49 MS - PKC beta encodes two proteins (PKCB1 and PKCBII) generated by alternative splicing of C-terminal exons. It is widely distributed with wide-ranging roles in processes such as B-cell receptor regulation, oxidative stress-induced apoptosis, androgen receptor-dependent transcriptional regulation, insulin signaling, and endothelial cell proliferation. HN - 2014 MH - Psychotherapy, Psychodynamic UI - D064889 MN - F4.754.775 MS - Forms of PSYCHOTHERAPY falling within or deriving from the psychoanalytic tradition, that view individuals as reacting to unconscious forces (e.g., motivation, drive), that focus on processes of change and development, and that place a premium on self understanding and making meaning of what is unconscious. HN - 2014 MH - Pteridophyta UI - D064027 MN - B1.650.940.900.500 MS - An extremely diverse group of approximately 12,000 species of FERNS and so-called fern allies. HN - 2014; use Ferns 2001-2013 MH - Qigong UI - D064906 MN - E2.190.525.186.500 MN - E2.779.474.124.500 MS - An ancient Chinese system of postures, exercises, breathing techniques, and meditations designed to improve and enhance the body's QI. HN - 2014 BX - Ch'i Kung BX - Qi Gong MH - Rabeprazole UI - D064750 MN - D2.886.640.74.750 MN - D3.383.725.24.750 MN - D3.438.103.34.750 MS - A 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. HN - 2014 MH - Racemethionine UI - D064697 MN - D2.886.30.676.89 MN - D12.125.142.557.500 MN - D12.125.154.549.500 MN - D12.125.166.676.89 MS - A preparation of METHIONINE that includes a mixture of D-methionine and L-methionine isomers. HN - 2014 MH - Racepinephrine UI - D064705 MN - D2.33.100.291.310.500 MN - D2.92.63.291.310.500 MN - D2.92.211.215.311.461.700 MN - D2.92.311.461.825 MS - A racemic mixture of d-epinephrine and l-epinephrine. HN - 2014; use EPINEPHRINE 1986-2013 FX - Receptors, Adrenergic MH - Receptor, Metabotropic Glutamate 5 UI - D064529 MN - D12.776.543.750.100.450.500 MN - D12.776.543.750.720.200.450.500.500 MS - A type I G protein-coupled receptor mostly expressed post-synaptic pyramidal cells of the cortex and CENTRAL NERVOUS SYSTEM. HN - 2014 BX - Metabotropic Glutamate Receptor 5 BX - Receptor 5, Metabotropic Glutamate MH - Recommended Dietary Allowances UI - D064167 MN - G7.610.620.500 MN - I1.655.500.608.400.650.500 MN - I1.880.604.825.608.400.650.500 MN - N3.623.500.608.428.650.500 MS - The amounts of various substances in the diet recommended by governmental guidelines as needed to sustain healthy life. HN - 2014; use NUTRITION POLICY 1998-2013 BX - Recommended Daily Allowances MH - Retrocaval Ureter UI - D064749 MN - C12.706.811 MN - C13.351.875.811 MN - C16.131.939.915 MS - A rare congenital abnormality resulting in the URETER passing dorsal to and being obstructed by the INFERIOR VENA CAVA. HN - 2014 FX - Ureter MH - Rho Guanine Nucleotide Exchange Factors UI - D064067 MN - D12.644.360.325.300.99 MN - D12.776.402.300.99 MN - D12.776.476.325.300.99 MS - Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways. HN - 2014 MH - Rickets, Hypophosphatemic UI - D063730 MN - C5.116.198.816.875 MN - C18.452.174.845.875 MN - C18.452.750.400.750 MN - C18.654.521.500.133.770.734.875 MS - A disorder characterized by HYPOPHOSPHATEMIA; RICKETS; OSTEOMALACIA; resulting from lack of phosphate reabsorption by the kidneys and possible defects in vitamin D metabolism. HN - 2014; use HYPOPHOSPHATEMIC RICKETS, X-LINKED DOMINANT 2006-2013; use HYPOPHOSPHATEMIA, FAMILIAL 1994-2006 BX - Rickets, Vitamin D-Resistant MH - Rural Nursing UI - D064694 MN - H2.478.676.806 MN - N2.421.816.500 MS - A branch of nursing requiring generalist training with specialty knowledge in crisis assessment and management in all subdisciplines of nursing. Rural nursing practices often include geographical and social distance concepts in delivery of health care. HN - 2014 MH - S100 Calcium Binding Protein beta Subunit UI - D064568 MN - D12.776.157.125.750.625 MN - D12.776.641.655.750 MS - A calcium-binding protein that is 92 AA long, contains 2 EF-hand domains, and is concentrated mainly in GLIAL CELLS. Elevation of S100B levels in brain tissue correlates with a role in neurological disorders. HN - 2014 MH - S100 Calcium Binding Protein G UI - D064030 MN - D12.776.157.125.90.500 MN - D12.776.157.125.750.750 MS - A calbindin protein found in many mammalian tissues, including the UTERUS, PLACENTA, BONE, PITUITARY GLAND, and KIDNEYS. In intestinal ENTEROCYTES it mediates intracellular calcium transport from apical to basolateral membranes via calcium binding at two EF-HAND MOTIFS. Expression is regulated in some tissues by VITAMIN D. HN - 2014(1979) MH - Safety-net Providers UI - D064876 MN - N4.590.374.700 MS - Providers that by mandate or mission organize and deliver a significant level of health care and other health-related services to the uninsured, Medicaid recipients, and other vulnerable patients. AN - use only for the facility and not for the personnel providing the health service HN - 2014 MH - Sagittal Abdominal Diameter UI - D064346 MN - E1.370.600.115.100.160.340 MN - E5.41.124.160.812 MN - G7.100.100.160.340 MS - The height of the ABDOMEN as measured in the SUPINE POSITION. HN - 2014 FX - Waist Circumference MH - Satellite Imagery UI - D063809 MN - E5.925.500.500 MN - L1.178.847.550.500 MN - L1.178.847.675.500.500 MS - Composition of images of EARTH or other planets from data collected during SPACE FLIGHT by remote sensing instruments onboard SPACECRAFT. The satellite sensor systems measure and record absorbed, emitted, or reflected energy across the spectra, as well as global position and time. HN - 2014 FX - Geographic Information Systems MH - Scorpion Stings UI - D065008 MN - C25.723.127.142 MN - C26.176.443 MS - The effects, both local and systemic, caused by the bite of SCORPIONS. HN - 2014 MH - Secondary Care Centers UI - D063728 MN - N2.278.421.745 MS - A healthcare facility equipped to provide all but the most specialized forms of care, surgery, and diagnostic techniques. HN - 2014 MH - Secondary Metabolism UI - D064210 MN - G3.495.553.875 MS - A physiochemical process which occurs in a wide range of organisms which unlike BASAL METABOLISM is not required for or essential to short-term survivability but to long-term general well-being of the organism. HN - 2014 FX - Basal Metabolism FX - Phytochemicals MH - Secretagogins UI - D064046 MN - D12.776.157.125.787 MS - Secretagogins are EF HAND MOTIF-containing calcium-binding proteins that are involved in early neuronal migration and neurogenesis. They are also present in many adult organs and in brain and endocrine neoplasms. HN - 2014 FX - EF Hand Motifs MH - Securin UI - D064249 MN - D12.776.167.504 MS - Securin is involved in the control of the metaphase-anaphase transition during MITOSIS. It promotes the onset of anaphase by blocking SEPARASE function and preventing proteolysis of cohesin and separation of sister CHROMATIDS. Overexpression of securin is associated with NEOPLASTIC CELL TRANSFORMATION and tumor formation. HN - 2014 MH - Selenic Acid UI - D064586 MN - D1.810.449 MS - A strong dibasic acid with the molecular formula H2SeO4. Included under this heading is the acid form, and inorganic salts of dihydrogen selenium tetraoxide. HN - 2014 MH - Selenium Oxides UI - D064588 MN - D1.810.950 MS - Inorganic compounds formed through the oxidation of selenium. HN - 2014 MH - Senior Centers UI - D064407 MN - N2.421.143.913 MN - N2.860 MS - Community centers for older adults and providers of resources for the community. In addition to providing services and activities for older adults that reflect the community's diversity, they link participants with resources offered by other agencies. HN - 2014 MH - Separase UI - D064247 MN - D8.811.277.656.262.500.792 MN - D8.811.277.656.300.200.792 MN - D12.776.167.552 MS - Separase is a caspase-like cysteine protease, which plays a central role in triggering ANAPHASE by cleaving the SCC1/RAD21 subunit of the cohesin complex. Cohesin holds the sister CHROMATIDS together during METAPHASE and its cleavage results in chromosome segregation. HN - 2014 MH - Sequestering Agents UI - D064449 MN - D27.505.519.914 MN - D27.720.832 MS - Compounds that bind to and reduce the biological availability of a chemical or pharmaceutical agent. HN - 2014 BX - Sequestering Agent MH - Serving Size UI - D064788 MN - G7.610.240.917 MS - A reference measure of food used to identify the calorie and nutrient content in a particular amount of that food. It is defined by an authoritative source, such as the Food Guide Pyramid devised by the UNITED STATES DEPARTMENT OF AGRICULTURE. It is different from PORTION SIZE, which is the amount of food one chooses to eat at a single meal. AN - PORTION SIZE is also available HN - 2014 MH - Slavery UI - D063947 MN - I1.880.735.384.800 MS - The status or condition of a person over whom any or all of the powers attaching to the right of ownership are exercised. The slave trade is all acts involved in the capture, acquisition or disposal of persons with intent to reduce them to enslavement; all acts involved in the acquisition of enslaved persons with a view to selling or exchanging them; all acts of disposal by sale or exchange of persons acquired with a view to being sold or exchanged, and, in general, every act of trade or transport of slaves. ( from http://www.ohchr.org/Documents/Publications/slaveryen.pdf accessed 10/18/2012) HN - 2014 FX - Slaves MH - Slaves UI - D063948 MN - M1.800 MS - A person involuntarily owned or controlled by another and exploited for forced or compulsory work or service. HN - 2014 FX - Slavery MH - SLC4A Proteins UI - D064606 MN - D12.776.157.530.450.437 MN - D12.776.543.550.779 MN - D12.776.543.585.450.437 MS - Bicarbonate transporters that move BICARBONATE IONS in exchange of CHLORIDE IONS or SODIUM IONS across membranes. They regulate acid-base HOMEOSTASIS, cell volume and intracellular pH. Members include CHLORIDE-BICARBONATE ANTIPORTERS (SLC4A1, 2, 3, and 9); SODIUM-COUPLED BICARBONATE TRANSPORTERS (SLC4A4 and 5, 7, 8 and 10); and a sodium borate cotransporter (SLC4A11 protein). HN - 2014 MH - Social Determinants of Health UI - D064890 MN - N1.224.425.762 MN - N1.400.675 MS - The circumstances in which people are born, grow up, live, work, and age, as well as the systems put in place to deal with illness. These circumstances are in turn shaped by a wider set of forces: economics, social policies, and politics (http://www.cdc.gov/socialdeterminants/). HN - 2014 MH - Social Validity, Research UI - D063586 MN - H1.770.644.932 MS - Evaluation of the degree of acceptance for the immediate variables associated with a procedure or program designed to change behavior. This includes the social significance of the goals of treatment, the social appropriateness of the treatment procedures, and the social importance of the effects of treatments. HN - 2014 FX - Program Evaluation MH - Solute Carrier Family 12, Member 1 UI - D064466 MN - D12.776.157.530.450.625.750.500 MN - D12.776.543.585.450.625.750.500 MS - Na-K-Cl transporter in the ASCENDING LIMB OF LOOP OF HENLE. It mediates active reabsorption of sodium chloride and is inhibited by LOOP DIURETICS such as FUROSEMIDE; and BUMETANIDE. Mutations in the gene encoding SLC12A1 are associated with a BARTTER SYNDROME. HN - 2014 FX - Bartter Syndrome MH - Solute Carrier Family 12, Member 2 UI - D064506 MN - D12.776.157.530.450.625.750.625 MN - D12.776.543.585.450.625.750.625 MS - Na-K-Cl transporter ubiquitously expressed. It plays a key role in salt secretion in epithelial cells and cell volume regulation in nonepithelial cells. HN - 2014 MH - Solute Carrier Family 12, Member 3 UI - D064486 MN - D12.776.157.530.450.625.374.500 MS - Na-Cl cotransporter in the convoluted segments of the DISTAL KIDNEY TUBULE. It mediates active reabsorption of sodium and chloride and is inhibited by THIAZIDE DIURETICS. HN - 2014 FX - Gitelman Syndrome MH - Solute Carrier Family 12, Member 4 UI - D064507 MN - D12.776.157.530.450.625.750.875 MN - D12.776.543.585.450.625.750.875 MS - K-Cl cotransporter ubiquitously expressed with higher expression levels in ERYTHROCYTES of ANEMIA, SICKLE CELL. It mediates active potassium and chloride cotransport across the plasma membrane and contributes to cell volume homeostasis HN - 2014 MH - Spike Glycoprotein, Coronavirus UI - D064370 MN - D12.776.543.512.500.665 MN - D12.776.964.970.880.910.665 MS - A class I viral fusion protein that forms the characteristic spikes, or peplomers, found on the viral surface that mediate virus attachment, fusion, and entry into the host cell. During virus maturation, it is cleaved into two subunits: S1, which binds to receptors in the host cell, and S2, which mediates membrane fusion. HN - 2014 BX - Spike Glycoproteins, Coronavirus MH - Spindle Pole Bodies UI - D064048 MN - A11.284.430.214.190.750.585.580 MN - A11.284.430.214.190.750.820.500.750 MS - Microtubule organizing centers of FUNGI and DIATOMS. They are embedded in the NUCLEAR ENVELOPE and evolve into the spindle apparatus during CELL DIVISION. HN - 2014 MH - Spindle Poles UI - D064047 MN - A11.284.430.214.190.750.820.500 MS - The sites in a dividing cell where the minus ends of the spindle MICROTUBULES assemble and where the separated sister CHROMATIDS converge. HN - 2014 MH - Sports for Persons with Disabilities UI - D064846 MN - I3.450.642.845.834 MS - Activities or games played by PERSONS WITH DISABILITIES, usually requiring physical effort or skill. The activities or games may be specifically created or based on existing sports, with or without modifications, to meet the needs of persons with physical or intellectual disabilities. HN - 2014 BX - Sports for the Disabled FX - Disabled Persons FX - Rehabilitation MH - Sports Nutritional Physiological Phenomena UI - D064133 MN - G7.610.830 MS - Nutritional physiology related to EXERCISE or ATHLETIC PERFORMANCE. HN - 2014 FX - Sports Nutritional Sciences MH - Sports Nutritional Sciences UI - D064132 MN - H2.403.830.500 MN - H2.533.645 MS - The study of NUTRITION PROCESSES during EXERCISE and ATHLETIC PERFORMANCE as well as specific NUTRITIONAL REQUIREMENTS of ATHLETES and the relationship between NUTRITIONAL STATUS and NUTRITION DISORDERS in athletes. HN - 2014 FX - Sports Nutritional Physiological Phenomena MH - Streptomyces rimosus UI - D064411 MN - B3.300.390.400.810.768.750 MN - B3.510.24.49.775.775.750 MN - B3.510.415.400.810.768.750 MN - B3.510.460.410.810.768.750 MS - An actinomycete best known as the producer of the commercially important antibiotic OXYTETRACYCLINE. HN - 2014 MH - Sublingual Immunotherapy UI - D063729 MN - E2.95.465.425.450.310.500 MN - E5.478.610.310.500 MS - A method of treating an ALLERGY by administering ALLERGENS, in liquid formulation or tablets, to the ORAL MUCOSA under the tongue. HN - 2014 MH - Sulfonylurea Receptors UI - D064233 MN - D12.776.157.530.400.600.450.550.500 MN - D12.776.157.530.400.600.450.775 MN - D12.776.543.550.425.750.450.550.500 MN - D12.776.543.585.100.805 MN - D12.776.543.585.400.750.450.550.500 MN - D12.776.827.775 MS - ATP-BINDING CASSETTE PROTEINS that are highly conserved and widely expressed in nature. They form an integral part of the ATP-sensitive potassium channel complex which has two intracellular nucleotide folds that bind to sulfonylureas and their analogs. HN - 2014 MH - Superficial Back Muscles UI - D064171 MN - A2.633.567.175.875 MS - The top layer of the back muscles whose function is to move the SCAPULA. This group of muscles consists of the trapezius, latissimus dorsi, rhomboid major, rhomboid minor and levator scapulae. HN - 2014 MH - Tatarstan UI - D064874 MN - Z1.542.248.775.900 MS - Political subdivision of eastern RUSSIA located within Europe. It lies between the Volga River and the Kama River, and extends east to the Ural mountains. HN - 2014 MH - Teach-Back Communication UI - D064871 MN - F1.145.209.719 MN - I2.233.332.874 MS - Providing the patient, family or others information, and then allowing them to take an action or restate the information in their own words. The clinician prefaces communications with a statement framed to show the clinician has the burden of effective communication rather than the patient. HN - 2014 FX - Professional-Patient Relations MH - Temperance Movement UI - D064830 MN - I3.833 MS - Social effort most active in the 19th and early 20th centuries dedicated to promoting moderation or complete abstinence in the use of ALCOHOLIC BEVERAGES. HN - 2014 MH - Teratogenesis UI - D064793 MN - C23.550.863 MS - The formation of CONGENITAL ABNORMALITIES. HN - 2014 FX - Abnormalities, Drug-Induced FX - Abnormalities, Radiation-Induced FX - Congenital Abnormalities FX - Mutagenesis FX - Teratogens FX - Teratology MH - Therapy, Soft Tissue UI - D064746 MN - E2.190.599.750 MN - E2.779.867.880 MS - The assessment, treatment, and management of soft tissue injury or dysfunction. Therapy is designed to reduce tension and irritation in affected tissues and may include MASSAGE; muscle stretching, or direct pressure on muscles, connective tissue, and TRIGGER POINTS. HN - 2014 BX - Soft Tissue Therapy MH - Tick Bites UI - D064927 MN - C25.723.127.789 MN - C26.176.793 MS - The effects, both local and systemic, caused by the bites of TICKS. HN - 2014 MH - Tobacco Use UI - D064424 MN - F1.145.928 MS - Uses of tobacco (Nicotiana L) and tobacco products. HN - 2014 BX - Tobacco Consumption MH - Torpor UI - D064348 MN - G7.110.232.889 MN - G7.700.345.421.889 MN - G16.100.57.500.535.889 MS - A state of decreased activity in animals characterized by depressed metabolism, reduced body temperature, and low sensitivity to external stimuli. HN - 2014 MH - Tracheobionta UI - D064028 MN - B1.650.940.900 MS - A subset of various vascular plants (also known as the Tracheophyta) which include seed-bearing and non seed-bearing species. HN - 2014; use Ferns 2001-2013 BX - Tracheophyta MH - Transfusion Medicine UI - D064826 MN - H2.403.429.445.500 MS - The area of hematology that is concerned with the transfusion of blood and blood components, and in prevention and treatment of adverse effects from BLOOD TRANSFUSION errors. HN - 2014 FX - Blood Safety MH - Trichomes UI - D064201 MN - A11.284.917 MN - A18.24.750.825 MS - Hair-like extensions on specialized epidermal surfaces of plants which protect against damage from insects, animals, light degradation and fungal infection. Trichomes may also occur on certain unicellular EUKARYOTES. HN - 2014 MH - Triple Negative Breast Neoplasms UI - D064726 MN - C4.588.180.788 MN - C17.800.90.500.788 MS - Breast neoplasms that do not express ESTROGEN RECEPTORS; PROGESTERONE RECEPTORS; and do not overexpress the NEU RECEPTOR/HER-2 PROTO-ONCOGENE PROTEIN. AN - coordinate IM with histological type of neoplasm (IM) HN - 2014 MH - Type B Personality UI - D064414 MN - F1.752.747.905 MS - Behavior pattern characterized by a generally calm and even-tempered demeanor. Emotionally, such personality types show less frequent irritation, anger, hostility, and aggression than Type A individuals. (from International Encyclopedia of the Social Sciences, 2008, p. 223) HN - 2014 MH - Type D Personality UI - D064415 MN - F1.752.747.917 MS - Behavior pattern characterized by negative emotionality, an inability to express emotions, and social isolation, which has been linked to greater cardiovascular disease and increased mortality. (from International Encyclopedia of the Social Sciences, 2008, p. 217) HN - 2014 MH - Ubiquitin-Specific Proteases UI - D064570 MN - D8.811.277.656.300.887 MS - Members of the peptidase C19 family which regulate signal transduction by removing UBIQUITIN from specific protein substrates via a process known as deubiquitination or deubiquitylation. HN - 2014 MH - Urological Agents UI - D064804 MN - D27.505.954.944 MS - Drugs used in the treatment of urogenital conditions and diseases such as URINARY INCONTINENCE; PROSTATIC HYPERPLASIA; and ERECTILE DYSFUNCTION. HN - 2014 MH - Vaccine Potency UI - D064166 MN - G12.300.500 MS - The relationship between an elicited ADAPTIVE IMMUNE RESPONSE and the dose of the vaccine administered. HN - 2014 MH - Vascularized Composite Allotransplantation UI - D063986 MN - E4.936.450.825 MS - Transference of multiple tissues, such as muscle, bone, nerve, and skin, as a functional unit for reconstructive purposes. Blood supply to the transplanted tissues is maintained throughout the transplantation procedure with minimal ischemia. Maintenance of vascularity in the graft promotes its viability, function, and survival in the recipient. AN - use for the surgical procedure; use VASCULARIZED COMPOSITE ALLOGRAFTS see COMPOSITE TISSUE ALLOGRAFTS for the graft itself HN - 2014 MH - Veterinary Sports Medicine UI - D064796 MN - H2.403.830.750 MN - H2.956.929 MS - The field of veterinary medicine concerned with PHYSICAL FITNESS of animals in sports (horse racing, dog racing, etc.) and the diagnosis and treatment of sports injuries in animals. HN - 2014 FX - Physical Conditioning, Animal MH - Visual Analog Scale UI - D064232 MN - E1.370.928 MS - A subjective psychometric response scale used to measure distinct behavioral or physiological phenomena based on linear numerical gradient or yes/no alternatives. HN - 2014 MH - Vitamin K Epoxide Reductases UI - D064417 MN - D8.811.682.690.708.961 MS - OXIDOREDUCTASES which mediate vitamin K metabolism by converting inactive vitamin K 2,3-epoxide to active vitamin K. HN - 2014 BX - Vitamin K Epoxidase MH - Vocal Cord Dysfunction UI - D064706 MN - C8.360.895 MN - C8.618.980 MN - C9.400.895 MS - A disorder characterized by an intermittent abnormal VOCAL CORDS movement toward the midline during inspiration or expiration resulting in upper AIRWAY OBSTRUCTION. HN - 2014 FX - Asthma, Exercise-Induced FX - Dysphonia MH - Wakefulness-Promoting Agents UI - D064690 MN - D27.505.954.427.220.612 MS - A specific category of drugs that prevent sleepiness by specifically targeting sleep-mechanisms in the brain. They are used to treat DISORDERS OF EXCESSIVE SOMNOLENCE such as NARCOLEPSY. Note that this drug category does not include broadly-acting central nervous system stimulants such as AMPHETAMINES. HN - 2014 BX - Wake-Promoting Agents MH - Warm-Up Exercise UI - D063996 MN - G11.427.590.530.698.277.968 MN - I3.350.750 MS - Physical activities done to prepare the body for more intense physical activities. HN - 2014; use EXERCISE 2009-2013 FX - Cool-Down Exercise MH - Waste Disposal Facilities UI - D064091 MN - N6.850.780.200.800.800.900.449 MN - N6.850.860.510.900.700 MS - Sites that receive and store WASTE PRODUCTS. Some facilities also sort, process, and recycle specific waste products. AN - specify geographic location if pertinent HN - 2014 MH - Web Browser UI - D064878 MN - L1.224.900.940 MN - L1.470.937 MS - Software application for retrieving, presenting and traversing information resources on the World Wide Web. HN - 2014 MH - Workplace Violence UI - D064450 MN - I1.198.240.856.912 MN - I1.880.735.900.912 MS - Threatened or actual attempt to harm others at place of employment. HN - 2014 MH - Zuclomiphene UI - D064696 MN - D2.455.426.559.389.150.700.125.750 MS - The cis or (Z)-isomer of clomiphene. HN - 2014; use CLOMIPHENE 1992-2013