C416943 TBX22 protein 2000 12 16 2000 12 18 2001 2001A 2002 amino acid sequence in first source; GenBank AF251684 4 *D020825 T-Box Domain Proteins Gene 2000 Sep 19;255(2):289-96 THA THA THA M0374731 TBX22 protein C0962536 0 T116 Amino Acid, Peptide, or Protein T431169 TBX22 protein 2000 12 16 T431170 TBX22 gene product 2000 12 16 C000045 obtusastyrene 1972 01 01 2000 07 31 2001 2002 RN given refers to cpd with unspecified isomeric designation; structure 0 *PHENOLS (72-75) *STYRENES (72-75) *D013267 Stilbenes Antimicrob Agents Chemother 1(3):263;1972 NLM CCR sjn M0040052 obtusastyrene C0600697 24126-82-7 T109 Organic Chemical T121 Pharmacologic Substance 21148-30-1 ((E)-isomer) M0040052 M0307350 M0040052 M0040051 T070052 obtusastyrene M0307350 obtusastyrene, (E)-isomer C0893828 21148-30-1 T109 Organic Chemical T121 Pharmacologic Substance M0040052 M0307350 T337350 obtusastyrene, (E)-isomer 1999 08 18 M0040051 4-cinnamylphenol C0600696 T109 Organic Chemical T121 Pharmacologic Substance M0040052 M0040051 T070051 4-cinnamylphenol C000011 5-(n-acetaminophenylazo)-8-oxyquinoline 1971 01 01 1991 07 10 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *QUINOLINES (71-75) D015125 Oxyquinoline *Q000031 analogs ; derivatives NLM IDX TPW M0040023 5-(n-acetaminophenylazo)-8-oxyquinoline C0600689 5-(p-acetamidophenylazo)-8-hydroxyquinoline 26424-51-1 T070023 5-(n-acetaminophenylazo)-8-oxyquinoline C000024 flavophosphine 1970 01 01 1997 05 19 1997 1998 1999 2000 2001 2002 structure 0 *D000166 Acridines Acta Histochem 35(1):86;1970 NLM TBT NLM M0040037 flavophosphine C0600691 3-amino-9-(p-aminophenyl)-7-methylacridine 10134-60-8 T070037 flavophosphine C000214 androst-16-en-3-one 1972 01 01 2000 07 31 2001 2002 boar taint steroid; RN given refers to (5alpha)-isomer 62 *ANDROSTANES (72-73) KETOSTEROIDS (73-76) *D000736 Androstenes Acta Endocrinol 79(3):619;1975 Acta Vet Scand 17:475;1976 Acta Vet Scand 1979;20(3):343 Biochem J 144:347;1974 Biochim Biophys Acta 496(2):547;1977 Experientia 1979;35(12):1674 Horm Res 9(5):254;1978 Immuniz Hormones Reprod Res WQ205 I6163i:189;1975 J Anim Sci 33(6):1293;1971 J Endocrinol 67(2):47;1975 J Reprod Fertil 48:51;1976 J Steroid Biochem 1979;11(1c)839 J Steroid Biochem 7(8):593;1974 Steroids 28(5):585;1976 Zentralbl Veterinaermed 24(2):103;1977 NLM CCR sjn M0040272 androst-16-en-3-one C0048754 18339-16-7 T110 Steroid T123 Biologically Active Substance 52225-35-1 ((5beta)-isomer) M0040272 M0307391 M0040272 M0040271 T070274 androst-16-en-3-one M0307391 androst-16-en-3-one, (5beta)-isomer C0893844 52225-35-1 T110 Steroid M0040272 M0307391 T337391 androst-16-en-3-one, (5beta)-isomer 1999 08 18 M0040271 5 alpha-androst-16-en-3-one C0097598 T110 Steroid T123 Biologically Active Substance M0040272 M0040271 T070273 5 alpha-androst-16-en-3-one C000032 adenosine arabinose 1971 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ADENOSINE (72-75) *ARABINOSE (71-75) ARABINOSE/*analogs (75-79) *D001087 Arabinonucleosides D000241 Adenosine *Q000031 analogs ; derivatives NLM NLM M0040045 adenosine arabinose C0600694 2006-02-2 T070045 adenosine arabinose C416942 light-harvesting protein, algal 2000 12 16 2000 12 18 2001 2001A 2002 amino acid sequence in first source (Galdieria sulphuraria); GenBank AJ012759 and AJ271717 3 *D010940 Plant Proteins Gene 2000 Sep 19;255(2):257-65 THA THA THA M0374730 light-harvesting protein, algal C0962535 0 T116 Amino Acid, Peptide, or Protein T431167 light-harvesting protein, algal 2000 12 16 T431168 lhc gene product, algal 2000 12 16 C000039 alpha-amino-4-isothiazolylacetic acid 1972 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ACETIC ACIDS (72-82) *D013844 Thiazoles NLM VSR NLM M0040050 alpha-amino-4-isothiazolylacetic acid C0600695 4-Isothiazoleacetic acid, alpha-amino- 34653-48-0 T070050 alpha-amino-4-isothiazolylacetic acid C045521 dinitrophenol-ovalbumin 1985 07 09 2000 12 18 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 24 *D004140 Dinitrophenols *D010047 Ovalbumin D006241 Haptens Respiration 1985;47(2):138 RLS CCR CCR M0132317 dinitrophenol-ovalbumin C0058301 0 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T162322 dinitrophenol-ovalbumin T162321 dinitrophenylovalbumin T162320 DNP-ovalbumin C000047 albitocin 1971 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 saponin consisting of a triterpene glycoside of glucose, rhamnose, xylose ; arabinose 0 SAPONINS (71-82) TRITERPENES (74-76) *D006027 Glycosides J Pharm Pharmacol 15:816;1963 Pathology 2(4):251;1970 NLM VSR NLM M0040053 albitocin C0600698 39301-00-3 T070053 albitocin C000049 algivant 1971 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D000276 Adjuvants, Immunologic Hormone and Metabolic Research 2(1):47;1970 NLM NLM M0040054 algivant C0600699 0 T070054 algivant C000050 alisol A 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 *CHOLESTENES (73-75) *D002783 Cholestenones NLM NLM M0040055 alisol A C0600700 19885-10-0 T070055 alisol A C000051 2-alkylaminobenzothiazole 1971 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 AMINES (71-76) *D013844 Thiazoles NLM NLM M0040056 2-alkylaminobenzothiazole C0600701 0 T070056 2-alkylaminobenzothiazole C000056 264 CP 1973 01 01 1980 11 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PIPERIDINES (73-76) ALLYL COMPOUNDS (73-76) *D001549 Benzamides NLM BGS NLM M0040061 264 CP C0600703 2-allyloxy-4-chloro-N-(2-piperidinoethyl)benzamide 25709-16-4 T070061 264 CP C000059 ametohepazone 1971 01 01 1994 04 28 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CYCLOHEPTANES (71-85) *D007093 Imidazoles NLM PML NLM M0040064 ametohepazone C0051568 2(1H)-Cycloheptimidazolone, 1-(2-(dimethylamino)ethyl)- 1019-19-8 T070064 ametohepazone C000060 9-(3-(aden-9-yl)propyl)-2-dimethylaminopurin-6-one 1972 01 01 1983 08 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ADENINE (72-75) *HYPOXANTHINES (72-82) D000225 Adenine *Q000031 analogs ; derivatives NLM JSL NLM M0040065 9-(3-(aden-9-yl)propyl)-2-dimethylaminopurin-6-one C0600704 28077-96-5 T070065 9-(3-(aden-9-yl)propyl)-2-dimethylaminopurin-6-one C008937 platyphylline 1974 01 01 2000 07 31 2001 2002 from Senecio platyphyllus; RN given refers to (1 alpha)-isomer; structure 7 SENICIO (74-81) *D011763 Pyrrolizidine Alkaloids Farm Zh 30(4):35;1975 Farm Zh 30(5):47;1975 Farm Zh 4:36;1978 Farmatsiia 26(1):46;1977 Ter Arkh 2:63;1978 Vrach Delo 5:63;1979 Vratch Delo 10(0):11;1973 NLM WXM sjn M0053219 platyphylline C0071275 480-78-4 T109 Organic Chemical T121 Pharmacologic Substance 20361-76-6 ((1alpha,15E)-isomer) 66641-38-1 (HCl) M0053219 M0310522 M0053219 M0310523 T083222 platyphylline Merck Index 8th Edn p 842 T083221 3-ethylidenedodecahydro-5-hydroxy-5,5-dimethyl-1,6- dioxacyclododecino(2,3,4gh)pyrrolizine-2,7-dione M0310522 platyphylline, (1alpha,15E)-isomer C0895708 20361-76-6 T109 Organic Chemical T121 Pharmacologic Substance M0053219 M0310522 T340522 platyphylline, (1alpha,15E)-isomer 1999 08 18 M0310523 platyphylline hydrochloride C0895709 66641-38-1 T109 Organic Chemical T121 Pharmacologic Substance M0053219 M0310523 T340523 platyphylline hydrochloride 1999 08 18 C000063 thiozamin 1971 01 01 1982 09 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *SULFONES (71-76) *D013882 Thiosemicarbazones D007918 Leprosy Q000188 drug therapy NLM VSR NLM M0040070 thiozamin C0600705 p-(p'-aminobenzenesulfonyl)benzaldehyde thiosemicarbazone 4094-36-4 T070070 thiozamin C000064 putreanine 1971 01 01 1980 11 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 7 *AMINO ACIDS (71-78) PROPIONATES (72-76) *D000599 Amino Acids, Diamino Seishin Shinkeigaku Zasshi 1979;81(2):141 Tetrahedron 26:4307 Vopr Neirokhir 6:48;1977 NLM BGS NLM M0040071 putreanine C0072630 N-(4-aminobutyl)-3-aminopropionic acid 25887-39-2 T070071 putreanine C000066 aminocinnamonitrile 1971 01 01 1980 10 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 NITRILES (71-81) *D002934 Cinnamates NLM NBM NLM M0040073 aminocinnamonitrile C0600707 1823-99-0 T070073 aminocinnamonitrile C005165 1,1-diphenyl-1-methoxy-3-benzylaminopropane 1973 01 01 2001 02 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *PROPYLAMINES (73-82) *D001559 Benzhydryl Compounds Wien Klin Wochenschr 85(27):503;1973 NLM TWD TWD M0046517 1,1-diphenyl-1-methoxy-3-benzylaminopropane C0602159 Benzenepropanamine, gamma-methoxy-gamma-phenyl-N-(phenylmethyl)- 14089-87-3 T109 Organic Chemical T121 Pharmacologic Substance M0046517 M0046519 T076520 1,1-diphenyl-1-methoxy-3-benzylaminopropane M0046519 St 4250 C0602160 T109 Organic Chemical T121 Pharmacologic Substance M0046517 M0046519 T076522 St 4250 Negwer, 4th ed, #4146 (HCl) T076521 St-4250 C000077 amylosubtilin G10x 1979 01 01 1982 12 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 no other information available 1/1/79 0 *D000681 Amylases Ukr Biokhim Zh 51(4):374;1979 NLM VSR NLM M0040076 amylosubtilin G10x C0600708 EC 3.2.1.- T070076 amylosubtilin G10x C000080 phenpentermine 1972 01 01 1978 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *BUTYLAMINES (72-78) *D000662 Amphetamines NLM NLM M0040079 phenpentermine C0600711 2-amino-2-methyl-3-phenylbutane 434-43-5 T070079 phenpentermine C416969 glutathione transferase M3-3 2000 12 18 2001 2002 functions as prostaglandin E synthase 2 *D005982 Glutathione Transferase D007527 Isoenzymes Neurochem Res 2000 May;25(5):733-6 SXK SXK M0374778 glutathione transferase M3-3 C0962554 EC 2.5.1. - T126 Enzyme T431255 glutathione transferase M3-3 2000 12 18 C412602 glutathione transferase M2-2 2000 08 30 2000 12 18 2000 2001 2001A 2002 prevents the formation of neurotoxic aminochrome and dopachrome by catalyzing the conjugation of dopamine and dopa o-quinone with glutathione 3 *D005982 Glutathione Transferase D007527 Isoenzymes Biochem Biophys Res Commun 2000 Jul 21;274(1):32-6 BMB SXK SXK M0368751 glutathione transferase M2-2 C0960372 EC 2.5.1.- T126 Enzyme T422909 glutathione transferase M2-2 2000 08 30 T422910 GST M2-2 2000 08 30 C000092 1-hydroxyindoloquinoxaline 1971 01 01 1982 09 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 INDOLES (71-82) *D011810 Quinoxalines NLM VSR NLM M0040096 1-hydroxyindoloquinoxaline C0600714 0 T070096 1-hydroxyindoloquinoxaline C000096 1,5-anhydroglucitol-6-phosphate 1972 01 01 1980 11 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 4 SORBITAL/analogs (75-81) *D006600 Hexosephosphates Biochim Biophys Acta 242(1):89;1971 NLM RLS NLM M0040097 1,5-anhydroglucitol-6-phosphate C0282694 17659-59-5 T070097 1,5-anhydroglucitol-6-phosphate C000100 aquayamycin 1971 01 01 1982 02 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 4 *BENZANTHRACENES (71-81) BENZANTHRACENES (81-82) PYRANS (71-76) D000880 Anthraquinones NLM NBM NLM M0040099 aquayamycin C0052252 9-(tetrahydro-4',5'-dihydroxy-6'-methyl-2'H-pyran-2'-yl)-3,4,4a,12b-tetrahydro-3,4a,8,12b-tetrahydroxy-3-methyl-benz(a)anthracene-1,7,12(2H)-trione 26055-63-0 T070099 aquayamycin C000102 Arachin 1975 01 01 1993 06 18 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 9 *D010940 Plant Proteins D010367 Arachis hypogaea Int J Peptide Protein Res 11(4):305;1978 Int J Peptide Protein Res 1980;15(1):67 Int J Peptide Protein Res 7:155;1975 NLM PML NLM M0040104 Arachin C0052299 1398-00-1 T070105 Arachin C000105 arylid 1970 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *SALICYLATES (70-75) ANILIDES (70-75) *D012457 Salicylamides Pneumonol Pol 44(2):125;1976 Pneumonol Pol 45(8):529;1977 NLM NLM M0040105 arylid C0052453 4',5-dichlorosalicylanilide 1147-98-4 T070106 arylid C000109 azabicyclane 1970 01 01 1995 08 18 1996 1997 1998 1999 2000 2001 2002 structure 1 *BICYCLO COMPOUNDS (80-95) *BRIDGED CPDS (70-79) AZA CPDS (74-79) *D019086 Bicyclo Compounds, Heterocyclic J Med Chem 19(1):184;1976 Psychopharmacology 1979;66(1):19 NLM MLH BVL M0040114 azabicyclane C0052742 21650-02-2 M0040114 M0040113 T070115 azabicyclane M0040113 azabicyclane citrate C0104787 M0040114 M0040113 T070114 azabicyclane citrate C008973 polyornithine 1974 01 01 2000 07 31 2001 2002 RN given refers to (L)-isomer 100 *ORNITHINE (74-75) ORNITHINE/analogs (79-80) *D010455 Peptides Biopolymers 12(9):1997;1973 J Biochem (Tokyo) 83(2):519;1978 JNCI 58(5):1229;1977 Microbiol Immunol 1979;23(11):1067 Thromb Res 1980;17(3-4):481 NLM WXM sjn M0053308 polyornithine C0071632 25104-12-5 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid D013501 Surface-Active Agents 26445-53-4 ((DL)-isomer) 27378-49-0 (HBr(L)-isomer) 59166-85-7 (methyl sulfate(L)-isomer) M0053308 M0310541 M0053308 M0310542 M0053308 M0310543 T083311 polyornithine T083310 poly-L-ornithine M0310541 polyornithine, (DL)-isomer C0917158 26445-53-4 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0053308 M0310541 T340541 polyornithine, (DL)-isomer 1999 08 18 M0310542 polyornithine, hydrobromide, (L)-isomer C0895718 27378-49-0 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0053308 M0310542 T340542 polyornithine, hydrobromide, (L)-isomer 1999 08 18 M0310543 polyornithine, methyl sulfate, (L)-isomer C0895719 59166-85-7 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0053308 M0310543 T340543 polyornithine, methyl sulfate, (L)-isomer 1999 08 18 C000115 jaligonic acid 1974 01 01 1986 07 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CARBOXYLIC ACIDS (74-82) *D014315 Triterpenes J Nat Prod 36(3):326;1973 NLM THA NLM M0040119 jaligonic acid C0600718 (2 beta,3 beta,4 alpha,20 beta)-2,3,23-trihydroxy- olean-12-ene-28,29-dioic acid 51776-39-7 T070120 jaligonic acid C075750 8-epi-prostaglandin F2alpha 1992 08 20 2000 12 18 1998 1999 2000 2001 2001A 2002 a potent preglomerular vasoconstrictor acting principally through thromboxane A2 receptor activation 90 D015237 Dinoprost *Q000031 analogs ; derivatives J Clin Invest 1992 Jul;90(1):136-41 BXB CCR CCR M0203994 8-epi-prostaglandin F2alpha C0170483 27415-26-5 T111 Eicosanoid D014662 Vasoconstrictor Agents T233999 8-epi-prostaglandin F2alpha T233997 8-epi-PGF2alpha T233998 8-epiprostaglandin F2alpha C000146 bactoprenol 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 *D013729 Terpenes Biochem J 122(5):45;1971 NLM NLM M0040160 bactoprenol C0081705 12777-41-2 T070161 bactoprenol C000150 2-azacyclononanone 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 affects CNS activity 0 CYCLOPARAFFINS (73-82) *D001372 Aza Compounds J Pharm Sci 60(7):1053;1971 NLM VSR NLM M0040167 2-azacyclononanone C0600728 935-30-8 T070168 2-azacyclononanone C414670 CN3OP regimen 2000 10 26 2000 11 30 2001 2002 chemotherapy protocol consisting of the above compounds; used in the treatment of relapsed/refractory Hodgkin's lymphoma 1 *D000971 Antineoplastic Combined Chemotherapy Protocols D003520 Cyclophosphamide D008942 Mitoxantrone D011241 Prednisone D014750 Vincristine Med Oncol 2000 Aug;17(3):195-202 BMB BMB M0371565 CN3OP regimen C0961477 0 T061 Therapeutic or Preventive Procedure T427243 CN3OP regimen 2000 10 26 C000192 valofane 1972 01 01 2000 07 31 2001 2002 neurotropic drug; RN given refers to cpd with unspecified isomeric designation 6 *LACTONES (76-82) VALERATES (72-80) D014508 Urea *Q000031 analogs ; derivatives Arch Inst Farm Exp Med 22(1-2):7;1970 Br J Pharmacol 1979;66(3):478P Przeg Lek 29(2):358;1972 NLM CCR sjn M0040226 valofane C0077996 3-furancarboxamide, N-(aminocarbonyl)tetrahydro-5-methyl-2-oxo-3-(2-propenyl)- 3258-51-3 T109 Organic Chemical T121 Pharmacologic Substance 72962-38-0 ((trans)-isomer) 72962-39-1 ((cis)-isomer) M0040226 M0307384 M0040226 M0307383 M0040226 M0040220 T070227 valofane Negwer, 5th ed, #6233 UD 29;15k UD 30;103k T070226 valofan T070220 2-allophenyl-2-allyl-gamma-valerolactone T070224 alpha-allophanyl-alpha-allyl-gamma-valerolactone T070225 alpha-allyl-alpha-allophanyl-gamma-valerolactone T070222 allophanyl allyl valerolactone T070223 allophanyl-1-allyl-1-valero-3-lactone M0307384 valofane, (cis)-isomer C0893842 72962-39-1 T109 Organic Chemical T121 Pharmacologic Substance M0040226 M0307384 T337384 valofane, (cis)-isomer 1999 08 18 M0307383 valofane, (trans)-isomer C0893841 72962-38-0 T109 Organic Chemical T121 Pharmacologic Substance M0040226 M0307383 T337383 valofane, (trans)-isomer 1999 08 18 M0040220 HH 10018 C0121740 T109 Organic Chemical T121 Pharmacologic Substance M0040226 M0040220 T070221 HH 10018 C000154 alpinumisoflavone 1972 01 01 1980 11 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 extract from twigs of poisonous British plant 2 PHENOLS (72-81) *D005419 Flavones J Chem Soc (ORG) 20(0):3389;1971 NLM BGS NLM M0040175 alpinumisoflavone C0600729 5-hydroxy-7-(p-hydroxyphenyl)-2,2-dimethyl-2H-6H-benzodipyran-6-one 34086-50-5 T070176 alpinumisoflavone C000156 N-acetylglucosaminuronic acid 1972 01 01 1982 09 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ACETYLGLUCOSAMINE/*analogs (75-82) *D014574 Uronic Acids Nature (New Biol)233(43):259;1971 NLM VSR NLM M0040176 N-acetylglucosaminuronic acid C0600730 D-Glucuronic acid, 2-(acetylamino)-2-deoxy- 34047-66-0 T070177 N-acetylglucosaminuronic acid C000232 azalomycin-F 1972 01 01 2001 01 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 5 *D000900 Antibiotics Antibiotiki 20(4):303;1975 J Jap Soc Obs and Gyn Soc 24(1):39;1972 NLM TWD TWD M0040301 azalomycin-F C0052748 11003-24-0 T070303 azalomycin-F T070302 azalomycin F C000163 benzylideneglucosamine 1971 01 01 1980 12 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *GLUCOSAMINE (71-75) BENZENE DERIVATIVES (71-75) BENZYLIDENE COMPOUNDS (75-81) D005944 Glucosamine *Q000031 analogs ; derivatives NLM BEJ NLM M0040179 benzylideneglucosamine C0600731 0 T070180 benzylideneglucosamine C000164 1-benzylindole 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 BENZYL COMPOUNDS (72-75) *D007211 Indoles Yakugaku Zasshi 91(8):818;1971 NLM NLM M0040180 1-benzylindole C0600732 3377-71-7 T070181 1-benzylindole C000165 EX-10-542A 1973 01 01 1980 12 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 PIPERIDINES (73-81) *D003984 Dibenzazepines NLM BEJ NLM M0040181 EX-10-542A C0059926 5-benzyl-11-(4-n-methyl piperidylene)-5,6-dihydromorphanthridine hydrogen maleate 23239-59-0 T070182 EX-10-542A UD 19:99C C006505 4-aminobicyclo(2,2,2)octane-1-carboxylic acid 1974 01 01 2000 07 31 2001 2002 structure 1 *AMINO ACIDS (1982-2000) *BRIDGED COMPOUNDS (1974-1975) BICYCLO COMPOUNDS (1975-1981) CARBOXYLIC ACIDS (1974-1975) *D000598 Amino Acids, Cyclic J Phys Chem 77(18):2191;1973 NLM jmp sjn M0049109 4-aminobicyclo(2,2,2)octane-1-carboxylic acid C0048033 13595-17-0 T116 Amino Acid, Peptide, or Protein T130 Indicator, Reagent, or Diagnostic Aid T079112 4-aminobicyclo(2,2,2)octane-1-carboxylic acid C000175 4-N-acetamido-2,2,6,6-tetramethylpiperidine-N-oxide 1972 01 01 1988 11 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 inhibitor which binds with lysozyme; structure 0 D003497 Cyclic N-Oxides D013113 Spin Labels J Mol Biol 61(1):194;1971 NLM TPW NLM M0040202 4-N-acetamido-2,2,6,6-tetramethylpiperidine-N-oxide C0600734 0 T070203 4-N-acetamido-2,2,6,6-tetramethylpiperidine-N-oxide C000178 3-acetoxy-5-indoldiazonium 1972 01 01 1982 10 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *INDOLES (72-82) *D003979 Diazonium Compounds J Histochem Cytochem 20(3):161;1972 NLM VSR NLM M0040203 3-acetoxy-5-indoldiazonium C0600735 0 T070204 3-acetoxy-5-indoldiazonium C000185 Acrofol 1972 01 01 1989 05 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 Russian drug; structure 0 *PROPIONATES (72-75) *D011426 Propionic Acids Gig Sanit 36(8):109;1971 NLM RJM NLM M0040213 Acrofol C0050583 3-chloro-2-ene-propionic acid 4312-97-4 T070214 Acrofol C414671 2-ethylestrone-3-O-sulfamate 2000 10 26 2001 2002 structure in first source 1 D004970 Estrone *Q000031 analogs ; derivatives Cancer Res 2000 Oct 1;60(19):5441-50 BMB BMB M0371566 2-ethylestrone-3-O-sulfamate C0961478 0 T125 Hormone T427246 2-ethylestrone-3-O-sulfamate 2000 10 26 T427247 2-EtEMATE 2000 10 26 C000190 allerglobulin 1975 01 01 1995 07 26 1996 1997 1998 1999 2000 2001 2002 human gamma globulin preparation selected for their histamino-protectant potency; for drug therapy of asthma ; eczema 2 *D005719 Gamma-Globulins Lyon Med 226(20):891;1971 NLM MLH BVL M0040218 allerglobulin C0051198 0 T070219 allerglobulin UD 21:152C C414672 MPP11 protein 2000 10 26 2001 2002 ortholog of MIDA1 ; ZUO1; may play oncogenic role in head ; neck cancer; amino acid sequence in first source 1 *D004268 DNA-Binding Proteins Cancer Res. 2000 Oct 1;60(19):5529-35 BMB BMB M0371567 MPP11 protein C0961479 0 T116 Amino Acid, Peptide, or Protein T427248 MPP11 protein 2000 10 26 T427249 MPP11 gene product 2000 10 26 C000196 amadinone 1973 01 01 1980 11 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 androgen antagonist 0 *PREGNADIENES (73-75) *D009649 Norpregnadienes Clin Pharmacol Therap 13(2):205;1972 NLM RLS NLM M0040230 amadinone C0600741 6-chloro-17-acetoxy-19-norpregnane-4,6-diene-3,20-dione 30781-27-2 T070231 amadinone C026772 chloroacetyl coenzyme A 1980 10 27 2001 01 24 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 5 ACETYL COENZYME A/*analogs (80-92) *D000105 Acetyl Coenzyme A Biochem Biophys Res Commun 1980;95(4):1642 RLS CCR CCR M0087600 chloroacetyl coenzyme A C0055388 34201-15-5 T117603 chloroacetyl coenzyme A T117601 chloroacetyl CoA T117602 coenzyme A, chloroacetyl C033104 2-bromoacetyl coenzyme A 1982 01 18 2001 01 24 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 4 ACETYL COENZYME A/*analogs (82-92) *D000105 Acetyl Coenzyme A Methods Enzymol 1981;72:578 MEG CCR CCR M0102887 2-bromoacetyl coenzyme A C0045950 7303-38-0 T132891 2-bromoacetyl coenzyme A T132889 2-bromoacetyl-CoA T132890 coenzyme A, 2-bromoacetyl C101348 vinylacetyl-coenzyme A 1996 10 21 2001 01 24 1999 2000 2001 2001A 2002 structure in first source 1 *D000105 Acetyl Coenzyme A Biochemistry 1996 Sep 10;35(36):11710-8 BMB CCR CCR M0265731 vinylacetyl-coenzyme A C0529645 0 T295736 vinylacetyl-coenzyme A T295734 coenzyme A, vinylacetyl- T295735 vinylacetyl-CoA C414673 1,1,1,3,3,3-hexafluoropropane 2000 10 26 2001 2002 1 *D006845 Hydrocarbons, Fluorinated Inhal Toxicol. 2000 Aug;12(8):751-63 BMB BMB M0371568 1,1,1,3,3,3-hexafluoropropane C0961480 690-39-1 T109 Organic Chemical T427250 1,1,1,3,3,3-hexafluoropropane 2000 10 26 T427251 1,1,1,3,3,3-HFP 2000 10 26 C025645 N-acetyl-S-(2-cyanoethyl)cysteine 1980 08 08 2001 01 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 major urinary metabolite of acrylonitrile; structure in first source 6 *NITRILES (80-81) D000111 Acetylcysteine *Q000031 analogs ; derivatives J Toxicol Environ Health 1980;6(2):273 RLS CCR CCR M0085250 N-acetyl-S-(2-cyanoethyl)cysteine C0067665 L-Cysteine, N-acetyl-S-(2-cyanoethyl)- 74514-75-3 T115253 N-acetyl-S-(2-cyanoethyl)cysteine T115251 NASCS T115252 S-cyanoethylmercapturic acid C000207 2-amino-4-methyl-5-hexenoic acid 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ALKENES (72-75) *D000614 Aminocaproic Acids Biochem Biophys Res Commun 47(1):290;1972 NLM NLM M0040259 2-amino-4-methyl-5-hexenoic acid C0600754 25535-11-9 T070261 2-amino-4-methyl-5-hexenoic acid C000212 ammoniacal silver 1972 01 01 1980 11 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 19 AMMONIA (75-81) *D012834 Silver Adv Neurol Sci (Tokyo) 15(4):927;1971 NLM NBM NLM M0040269 ammoniacal silver C0051702 0 T070271 ammoniacal silver C053445 S-trichlorovinyl-N-acetylcysteine 1987 09 29 2001 01 24 1995 1996 1997 1998 1999 2000 2001 2001A 2002 6 D000111 Acetylcysteine *Q000031 analogs ; derivatives Biochem Pharmacol 1987;36(17):2741 RLS CCR CCR M0151432 S-trichlorovinyl-N-acetylcysteine C0084444 111348-61-9 T181437 S-trichlorovinyl-N-acetylcysteine T181435 N-acetyl-S-(trichlorovinyl)cysteine T181436 TCVAC C055229 S-(2-bromophenyl)mercapturic acid 1988 04 19 2001 01 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 D000111 Acetylcysteine *Q000031 analogs ; derivatives J Anal Toxicol 1988;12(1):42 TPW CCR CCR M0155594 S-(2-bromophenyl)mercapturic acid C0633131 113276-92-9 T185599 S-(2-bromophenyl)mercapturic acid T185598 ortho-bromophenylmercapturic acid T185597 O-BPMA C055230 S-(3-bromophenyl)mercapturic acid 1988 04 19 2001 01 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 D000111 Acetylcysteine *Q000031 analogs ; derivatives J Anal Toxicol 1988;12(1):42 TPW CCR CCR M0155597 S-(3-bromophenyl)mercapturic acid C0633134 113276-93-0 T185602 S-(3-bromophenyl)mercapturic acid T185600 M-BPMA T185601 meta-bromophenylmercapturic acid C067732 N-acetyl-S-(2,5-dihydroxyphenyl)cysteine 1991 04 10 2001 01 24 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 urinary metabolite of benzene, phenol ; hydroquinone; structure given in first source; RN given refers to (L)-isomer; RN for cpd without isomeric designation not avail 4/91 1 D000111 Acetylcysteine *Q000031 analogs ; derivatives Drug Metab Dispos 1990;18(6):958 RLS CCR CCR M0185566 N-acetyl-S-(2,5-dihydroxyphenyl)cysteine C0644663 39484-09-8 M0185566 M0185564 T215571 N-acetyl-S-(2,5-dihydroxyphenyl)cysteine T215570 NAc-DPC M0185564 N-acetyl-S-(2,5-dihydroxyphenyl)-L-cysteine C0644661 M0185566 M0185564 T215569 N-acetyl-S-(2,5-dihydroxyphenyl)-L-cysteine C000231 azacrin 1972 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 PYRIDINES (72-82) *D011804 Quinolines Toxicol Appl Pharmacol 21(4):482;1972 NLM VSR NLM M0040299 azacrin C0600758 2-methoxy-7-chloro-10-(4-(diethylamino-1-methyl)butylamino)pyrido(3,2-b)quinoline 34957-04-5 T070301 azacrin C000249 benzylsuccinic acid 1972 01 01 1998 01 28 1998 1999 2000 2001 2002 inhibitor of carboxypeptidase A 11 BENZYL COMPOUNDS (72-75) *D013386 Succinates J Biol Chem 247(2):606;1972 NLM BMB NLM M0040318 benzylsuccinic acid C0053330 884-33-3 T070320 benzylsuccinic acid C000252 betalamic acid 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 ALDEHYDES (72-76) DICARBOXYLIC ACIDS (72-76) *D011725 Pyridines Hoppe Seyler's Z Physiol Chem 353(2):127;1972 NLM NLM M0040321 betalamic acid C0600767 18766-66-0 T070323 betalamic acid C000253 bicyclophenamine 1972 01 01 1980 12 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *BICYCLO COMPOUNDS (75-81) *BRIDGED CPDS (72-75) *D011759 Pyrrolidines NLM BEJ NLM M0040322 bicyclophenamine C0053564 2-phenylbicyclo(2.2.1)heptane-2-carboxylic acid beta-pyrrolidinoethyl ester 3570-06-7 T070324 bicyclophenamine Negwer #3617 C000261 N-acetylethyleneimine 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 7 *D001389 Azirines Lab Pract 24(6):404;1975 NLM NLM M0040333 N-acetylethyleneimine C0067699 460-07-1 T070335 N-acetylethyleneimine C000268 Basofer 1971 01 01 1982 09 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D001285 Atropine *D010206 Papain D004338 Drug Combinations D002021 Buffers NLM VSR NLM M0040346 Basofer C0600768 Benzeneacetic acid, alpha-(hydroxymethyl)- 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester endo-(+-)-, mixt. with papain 77124-29-9 T070348 Basofer C000269 bikaverin 1972 01 01 1983 05 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 3 *D014966 Xanthenes Biochem Pharmacol 26:1973;1977 Folia Microbiol 20(4):340;1975 J Antibiotics 31(6):616;1978 J Chem Soc Perkin I 5:499;1976 Neoplasma 22(3):335;1975 NLM DLJ NLM M0040347 bikaverin C0053576 7,10-dihydro-6,11-dihydroxy-3,8-dimethoxy-1-methyl-12H-benzo(b)xanthene-7,10,12-trione 33390-21-5 T070349 bikaverin C000273 N,N'-bis(4-aminophenyl)-1,3-xylylenediamine 1972 01 01 1980 12 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 osmiophilic reagent 0 *AMINES (72-74) *XYLENES (72-75) ANILINE COMPOUNDS (75-81) *D003959 Diamines J Histochem Cytochem 19(10):611;1971 NLM BEJ NLM M0040349 N,N'-bis(4-aminophenyl)-1,3-xylylenediamine C0600769 1,3-Benzenedimethanamine, N,N'-bis(4-aminophenyl)- 26114-58-9 T070351 N,N'-bis(4-aminophenyl)-1,3-xylylenediamine C033367 MM antigen 1982 02 12 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 alloantigen from mammary tumors 14 *D000951 Antigens, Neoplasm *D007519 Isoantigens J Immunol 1982;128(1):201 RLS WXM WXM M0103553 MM antigen C0066660 0 M0103553 M0103551 M0103553 M0103549 M0103553 M0103550 T133557 MM antigen T133556 antigen, MM T133550 AMMT M0103551 alloantigen, LY 6.2 C0102231 M0103553 M0103551 T133555 alloantigen, LY 6.2 T133552 Lilly 6.2 alloantigen T133551 LY 6.2 alloantigen M0103549 MM46 C0128690 M0103553 M0103549 T133553 MM46 M0103550 MM48 C0128691 M0103553 M0103550 T133554 MM48 C042384 colonic-gastric mucus-associated antigens 1984 09 18 2001 01 25 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 oncofetal markers for intestinal neoplasms; see also record for fetal sulfoglycoprotein antigen 25 *D000951 Antigens, Neoplasm Cancer Res 1984;44(9):4040 RLS WXM WXM M0125196 colonic-gastric mucus-associated antigens C0056133 0 M0125196 M0125192 M0125196 M0125193 T155201 colonic-gastric mucus-associated antigens T155199 intestinal mucus-associated antigens T155196 colonic mucus antigen T155200 small intestinal mucin antigen T155195 SIMA M0125192 gastric M1 antigens C0118853 M0125196 M0125192 T155197 gastric M1 antigens M0125193 intestinal M3C antigens C0123786 M0125196 M0125193 T155198 intestinal M3C antigens C000286 N-bis(2-fluoroethyl)triazene 1972 01 01 1980 12 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *NITROGEN MUSTARD COMPOUNDS (72-81) *D014226 Triazenes NLM BEJ NLM M0040360 N-bis(2-fluoroethyl)triazene C0600774 0 T070362 N-bis(2-fluoroethyl)triazene C000287 bis(3-hydroxypropyl)trisulfide 1971 01 01 1980 12 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ALCOHOL, PROPYL (71-75) ALCOHOL, PROPYL/analogs (75-81) *D013440 Sulfides NLM BEJ NLM M0040361 bis(3-hydroxypropyl)trisulfide C0600775 29229-36-5 T070363 bis(3-hydroxypropyl)trisulfide C000291 AY 9928 1973 01 01 2000 07 31 2001 2002 RN ; NM refers to di-HCl 0 *METHYLAMINES (73-80) CYCLOHEXANES (73-80) *D003510 Cyclohexanes NLM CCR sjn M0040371 AY 9928 C0600779 1,4-cyclohexanedimethanamine, N,N'-bis(1-naphthalenylmethyl)-, dihydrochloride 1257-14-3 T109 Organic Chemical 7303-04-0 (di-HCl(cis)-isomer) 7303-05-1 (di-HCl(trans)-isomer) M0040371 M0307400 M0040371 M0307401 M0040371 M0040370 T070373 AY 9928 T070371 AY-9928 M0307400 AY 9928, dihydrochloride, (cis)-isomer C0893848 7303-04-0 T109 Organic Chemical M0040371 M0307400 T337400 AY 9928, dihydrochloride, (cis)-isomer 1999 08 18 M0307401 AY 9928, dihydrochloride, (trans)-isomer C0893849 7303-05-1 T109 Organic Chemical M0040371 M0307401 T337401 AY 9928, dihydrochloride, (trans)-isomer 1999 08 18 M0040370 N,N'-bis(1-naphthylmethyl)-1,4-cyclohexanebis(methylamine).2HCl C0600778 T109 Organic Chemical M0040371 M0040370 T070372 N,N'-bis(1-naphthylmethyl)-1,4-cyclohexanebis(methylamine).2HCl C001033 DMB-rifampicin 1973 01 01 2000 07 31 2001 2002 inhibitor of nucleic acid polymerases; RN given refers to cpd without isomeric designation 0 *RIFAMPIN (74-75) BENZYL CPDS (73-76) D012293 Rifampin *Q000031 analogs ; derivatives Biochem Biophys Res Comm 53(1):194;1973 Chem Biol Interact 18(1):59;1977 Invest Urol 14(5):366;1977 Nature New Biol 242(116):88;1973 Oncology 35:76;1978 NLM CCR sjn M0041096 DMB-rifampicin C0058534 13292-47-2 T109 Organic Chemical T121 Pharmacologic Substance 55297-68-2 ((cis)-isomer) M0041096 M0307532 T071099 DMB-rifampicin T071096 2',6'-dimethyl-N(4')-benzyl-N(4')(desmethylrifampicin) T071097 2,5-dimethyl-4-N-benzyldemethylrifampicin T071098 AF/ABDMP M0307532 DMB-rifampicin, (cis)-isomer C0893936 55297-68-2 T109 Organic Chemical T121 Pharmacologic Substance M0041096 M0307532 T337532 DMB-rifampicin, (cis)-isomer 1999 08 18 C000293 bisnoryangonin 1972 01 01 1980 12 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 extract from mushrooms 1 *PYRANS (72-75) PLANT EXTRACTS (73-76) STYRENES (72-81) *D011753 Pyrones Arch Biochem Biophys 169:84;1975 J Pharm Sci 61(2):318;1972 J Pharm Sci 67(4):485;1978 NLM BEJ NLM M0040372 bisnoryangonin C0053797 4-hydroxy-6-(4-hydroxystyryl)-2-pyrone 13709-27-8 T070374 bisnoryangonin C000277 EL 241 1971 01 01 2001 01 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent compound; presence in urine characteristic of aspartylgluucosaminuria; structure. 0 ALCOHOL, METHYL (71-75) CHLOROBENZENES (74-81) *D011725 Pyridines NLM TWD TWD M0040352 EL 241 C0600772 alpha-alpha-bis(p-chlorophenyl)-3-pyridine methanol 17781-31-6 T070354 EL 241 T070353 EL-241 C001054 N,N-dimethyl-2-phenylaziridinium 1970 01 01 2000 07 31 2001 2002 RN given refers to parent cpd without isomeric designation 10 *AZIRINES (70-75) DIMETHYLAMINES (73-76) *D001388 Aziridines NLM CCR sjn M0041134 N,N-dimethyl-2-phenylaziridinium C0067372 2641-72-7 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid 18945-82-9 (bromide.HBr) 7244-65-7 ((-)-isomer) M0041134 M0307546 M0041134 M0307545 M0041134 M0041133 T071137 N,N-dimethyl-2-phenylaziridinium T071135 N,N-DM2PA M0307546 N,N-dimethyl-2-phenylaziridinium, (-)-isomer C0893942 7244-65-7 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0041134 M0307546 T337546 N,N-dimethyl-2-phenylaziridinium, (-)-isomer 1999 08 18 M0307545 N,N-dimethyl-2-phenylaziridinium, hydrobromide C0893941 18945-82-9 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0041134 M0307545 T337545 N,N-dimethyl-2-phenylaziridinium, hydrobromide 1999 08 18 M0041133 N,N-dimethyl-2-phenylaziridinium ion C0129945 T130 Indicator, Reagent, or Diagnostic Aid T196 Element, Ion, or Isotope M0041134 M0041133 T071136 N,N-dimethyl-2-phenylaziridinium ion C038307 fexinidazole 1983 06 27 2001 08 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 6 *D009593 Nitroimidazoles Ann Trop Med Parasitol 1983;77(1):13 MGR jmp jmp M0115392 fexinidazole C0060304 59729-37-2 T109 Organic Chemical T121 Pharmacologic Substance M0115392 M0115391 T145396 fexinidazole M0115391 HOE 239 C0122174 T109 Organic Chemical T121 Pharmacologic Substance M0115392 M0115391 T145395 HOE 239 C000297 bithionol sulfoxide 1971 01 01 2001 08 17 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 7 *PHENOLS (71-75) D001735 Bithionol *Q000031 analogs ; derivatives Res. Vet. Sci 18(1):109;1975 NLM CCR CCR M0040388 bithionol sulfoxide C0053814 844-26-8 55511-30-3 (mono-Na salt) M0040388 M0040385 M0040388 M0307408 T070390 bithionol sulfoxide T070389 bis(3,5-dichloro-2-hydroxyphenyl)sulfoxide T070388 bis(2-hydroxy-3,5-dichlorophenyl)sulfoxide M0040385 Bitin-S C0106573 M0040388 M0040385 T070387 Bitin-S M0307408 bithionol sulfoxide, monosodium salt C0950988 55511-30-3 M0040388 M0307408 T337408 bithionol sulfoxide, monosodium salt 1999 08 18 C418762 9,12-dioxo-10(Z)-dodecenoic acid 2001 01 25 2001 2002 structure in first source 1 *D005229 Fatty Acids, Monounsaturated Lipids 2000 Sep;35(9):953-60 BMB BMB M0377130 9,12-dioxo-10(Z)-dodecenoic acid C0963480 0 T119 Lipid T434047 9,12-dioxo-10(Z)-dodecenoic acid 2001 01 25 T434048 9,12-DD acid 2001 01 25 C418763 2',3'-dideoxy-3'-fluorocytidine 2001 01 25 2001 2002 structure in first source 1 D003841 Deoxycytidine *Q000031 analogs ; derivatives Carbohydr Res 2000 Aug 18;328(1):49-59 BMB BMB M0377131 2',3'-dideoxy-3'-fluorocytidine C0963481 0 T114 Nucleic Acid, Nucleoside, or Nucleotide T434049 2',3'-dideoxy-3'-fluorocytidine 2001 01 25 T434051 3-FLT cpd 2001 01 25 T434050 2',3'-dideoxy-3'-fluoro-alpha-L-cytidine 2001 01 25 C000312 4-bromobenzylisothiocyanate 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 BENZYL COMPOUNDS (72-75) *D013861 Thiocyanates Chem Biol Interactions 4(5):305;1972 NLM NLM M0040406 4-bromobenzylisothiocyanate C0048126 2076-56-4 T070408 4-bromobenzylisothiocyanate C097501 acetyl coenzyme A-salutaridinol-7-O-acetyltransferase 1996 02 06 2001 01 25 1996 1997 1998 1999 2000 2001 2001A 2002 catalyzes the transfer of acetyl from acetyl coenzyme A to the 7-OH group of salutaridinol which yields salutaridinol-7-O-acetate, an intermediate in morphine biosynthesis; from Papaver somniferum plant cell cultures 2 *D000123 Acetyltransferases J Biol Chem 1995 Dec 29;270(52):31091-6 PML CCR CCR M0256301 acetyl coenzyme A-salutaridinol-7-O-acetyltransferase C0385481 EC 2.3.1.- T286306 acetyl coenzyme A-salutaridinol-7-O-acetyltransferase T286304 acetyl CoA-salutaridinol-7-O-acetyltransferase T286305 salutaridinol-7-O-acetyltransferase C000318 4-bromopyrazole 1970 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 BROMINE (72-75) *D011720 Pyrazoles NLM NLM M0040414 4-bromopyrazole C0048140 2075-45-8 T070416 4-bromopyrazole C000319 6-bromoquinazolone 1971 01 01 1986 07 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 BROMINE (71-75) *D011799 Quinazolines NLM THA NLM M0040415 6-bromoquinazolone C0600789 0 T070417 6-bromoquinazolone C110880 Hat1 acetyltransferase 1998 03 17 2001 01 25 1998 1999 2000 2001 2001A 2002 acetylates histone H4 at lysines 5 and 12; amino acid sequence of human (hsHAT1p) and Saccharomyces cerevisiae (scHat1p) enzymes in first source; GenBank T78280 (human) 9 *D000123 Acetyltransferases Curr Biol 1998 Jan 15;8(2):96-108 BVL CCR CCR M0287329 Hat1 acetyltransferase C0671924 EC 2.3.1.- M0287329 M0287327 M0287329 M0287328 T317334 Hat1 acetyltransferase M0287327 hsHat1p C0671922 M0287329 M0287327 T317332 hsHat1p M0287328 scHat1p C0671923 M0287329 M0287328 T317333 scHat1p C038153 CMESA-sepharose 1983 06 21 2001 08 17 1997 1998 1999 2000 2001 2001A 2002 1 *SEPHAROSE/analogs (83-83) D012685 Sepharose *Q000031 analogs ; derivatives Biochemistry 1983;22(10):2537 RLS jmp jmp M0114988 CMESA-sepharose C0618723 0 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T144991 CMESA-sepharose T144992 O-carboxymethylagarose ethylenediamine-succinyl-17 beta-O-4,6-androstadien-3-one C038613 citrullinase 1983 08 08 2001 08 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 2 *D000581 Amidohydrolases MGG 1983;190(2):278 MEG jmp jmp M0116135 citrullinase C0163985 EC 3.5.1.20 T116 Amino Acid, Peptide, or Protein T126 Enzyme T146139 citrullinase T146138 citrulline hydrolase C000334 butanediol divinylether 1972 01 01 1997 07 11 1998 1999 2000 2001 2002 VINYL ETHER (72-85) is no longer an active MH 0 *BUTANEDIOLS (75-81) *GLYCOLS (72-75) *D002072 Butylene Glycols *D004987 Ethers Europ J Biochem 25(1):129;1972 NLM ADP BVL M0040429 butanediol divinylether C0600791 3891-33-6 T070431 butanediol divinylether C432870 palicoside 2001 08 17 2001 2002 structure in first source 1 *D000470 Alkaloids *D009005 Monosaccharides Phytochemistry 2001 Jul;57(5):653-9 SZM SZM M0395793 palicoside C0968679 0 T109 Organic Chemical T118 Carbohydrate T457785 palicoside 2001 08 17 C000343 N-t-butyl-5-methyl isoxazolium perchlorate 1972 01 01 1978 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *OXAZOLES (72-78) PERCHLORIC ACIDS (72-75) *D007555 Isoxazoles Br J Pharmacol 43(3):514;1971 NLM NLM M0040441 N-t-butyl-5-methyl isoxazolium perchlorate C0600802 10513-45-8 T070443 N-t-butyl-5-methyl isoxazolium perchlorate C000357 cannabivarin 1971 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CANNABIS (71-79) *D002186 Cannabinoids Nature 232(5312):579;1971 NLM NLM M0040456 cannabivarin C0600804 33745-21-0 T070458 cannabivarin C001079 2-(2,6-dioxopiperidin-3-yl)phthalimidine 1972 01 01 2000 07 31 2001 2002 thalidomide analog; structure; RN given refers to cpd without isomeric designation 16 *PYRROLIDINONES (72-75) *THALIDOMIDE (72-75) D013792 Thalidomide *Q000031 analogs ; derivatives Teratology 19(3):341;1979 Teratology 5(2):233;1972 NLM CCR sjn M0041166 2-(2,6-dioxopiperidin-3-yl)phthalimidine C0091961 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione 26581-81-7 T109 Organic Chemical T131 Hazardous or Poisonous Substance 103794-93-0 ((+-)-isomer) 107657-57-8 ((S)-isomer) 107740-48-7 ((R)-isomer) M0041166 M0041168 M0041166 M0307551 M0041166 M0307553 M0041166 M0307552 T071169 2-(2,6-dioxopiperidin-3-yl)phthalimidine M0041168 EM 12 C0950161 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0041166 M0041168 T071171 EM 12 T071170 EM-12 M0307551 2-(2,6-dioxopiperidin-3-yl)phthalimidine, (+-)-isomer C0893945 103794-93-0 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0041166 M0307551 T337551 2-(2,6-dioxopiperidin-3-yl)phthalimidine, (+-)-isomer 1999 08 18 M0307553 2-(2,6-dioxopiperidin-3-yl)phthalimidine, (R)-isomer C0893947 107740-48-7 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0041166 M0307553 T337553 2-(2,6-dioxopiperidin-3-yl)phthalimidine, (R)-isomer 1999 08 18 M0307552 2-(2,6-dioxopiperidin-3-yl)phthalimidine, (S)-isomer C0893946 107657-57-8 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0041166 M0307552 T337552 2-(2,6-dioxopiperidin-3-yl)phthalimidine, (S)-isomer 1999 08 18 C000364 Captostibone (g) 1971 01 01 1987 03 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 SULFIDES (71-75) *D009942 Organometallic Compounds D000965 Antimony NLM PEH NLM M0040463 Captostibone (g) C0600805 sodium 2-(carboxymethylmercapto)benzene stibonate 36524-24-0 T070465 Captostibone (g) C432871 dolichantoside 2001 08 17 2001 2002 structure in first source 1 *D000470 Alkaloids *D009005 Monosaccharides Phytochemistry 2001 Jul;57(5):653-9 SZM SZM M0395795 dolichantoside C0968681 0 T109 Organic Chemical T118 Carbohydrate T457787 dolichantoside 2001 08 17 C000390 carnitylcholine 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CARNITINE (72-75) *CHOLINE (72-75) D002331 Carnitine *Q000031 analogs ; derivatives D002794 Choline *Q000031 analogs ; derivatives Biochem Pharmacol 20(12):3385;1971 NLM NLM M0040488 carnitylcholine C0600811 34566-86-4 T070490 carnitylcholine C000395 cephachlomezine 1972 01 01 1982 09 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 PIPERAZINES (72-82) *D002511 Cephalosporins J Antibiotics 24(10):667;1971 NLM VSR NLM M0040491 cephachlomezine C0600813 7-(m-chlorophenylacetamido)-3-(4,4-dimethylpiperazinium-1-thiocarbonyl-thiomethyl)-3-cephem-4-carboxylate 22561-27-9 T070493 cephachlomezine C000398 ceramide monohexoside sulfate 1972 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CERAMIDES (72-76) *GLYCOSPHINGOLIPIDS (76-79) SULFATES (72-74) *D002554 Cerebrosides Jpn J Exp Med 45(3):231;1975 NLM NLM M0040492 ceramide monohexoside sulfate C0055095 0 T070494 ceramide monohexoside sulfate C000402 chinophene 1971 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CARBOXYLIC ACIDS (72-76) *D011804 Quinolines NLM NLM M0040497 chinophene C0600814 11139-62-1 T070499 chinophene Negwer # 1901 C000410 1-(4-chlorobenzoyl)-5-dimethylamino-2-methylindole acetic acid 1972 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 indomethacin analog; structure 0 *CHLOROBENZOATES (75-79) *INDOLEACETIC ACIDS (72-79) BENZOATES (72-75) D007213 Indomethacin *Q000031 analogs ; derivatives J Pharm Sci 60(7):1053;1971 NLM TWD TWD M0040513 1-(4-chlorobenzoyl)-5-dimethylamino-2-methylindole acetic acid C0600826 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-(dimethylamino)-2-methyl- 23456-71-5 T070515 1-(4-chlorobenzoyl)-5-dimethylamino-2-methylindole acetic acid T070514 1-(p-chlorobenzoyl)-5-dimethylamino-2-methylindole acetic acid C024125 feto-specific proteins 1980 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 proteins that find principal quantitative expression in prenatal state 1 *D005326 Fetal Proteins Biochem Soc Trans 7(6):1179;1979 NLM WXM WXM M0082080 feto-specific proteins C0060298 0 T112083 feto-specific proteins T112082 foeto-specific proteins C104419 Apg-1 protein 1997 03 11 2000 10 12 1997 1998 1999 1999A 2000 2000A 2001 2002 expressed at low temperatures in the testis; amino acid sequence in first source; GenBank D49482 and D70845; human mapped to chromosome 4; GenBank AB023421 8 *D006360 Heat-Shock Proteins J Biol Chem 1997 Jan 31;272(5):2640-5 THA WXM WXM M0272756 Apg-1 protein C0535911 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T302761 Apg-1 protein T302760 apg-1 gene product C000515 cremophor EL 1972 01 01 2001 01 25 1998 1999 2000 2001 2001A 2002 solvent for Althesin ; Propanidid implicated as possible cause of similar adverse effects polyethoxylated castor oil; RN given refers to cpd with unknown MF; see also records for cremophor ; cremophor A 178 *CASTOR OIL (72-82) *ETHYLENE OXIDE (72-76) *POLYETHYLENE GLYCOLS (79-80) D005990 Glycerol *Q000031 analogs ; derivatives D012997 Solvents D014677 Vehicles Agents Actions 7(1):63;1975 Br J Anaesth 1979;51(2):1175 Br Med J 1(6060):575;1975 Br Med J 2(6141):897;1978 Br Med J 2(6149):1431;1978 NE J Med 296(25):1479;1977 Rec Prog Anaesthesiol Ressus WE EX 89 no. 347:116;1974 Toxicol Appl Pharmacol 19(4):721;1971 NLM TWD TWD M0040672 cremophor EL C0056476 63393-92-0 D013501 Surface-Active Agents T070674 cremophor EL T070673 cremophore EL C000414 5-chloro-3-tert-butyl-2'-nitrososalicylanilide 1975 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *SALICYLAMIDES (75-79) *D012458 Salicylanilides NLM NLM M0040519 5-chloro-3-tert-butyl-2'-nitrososalicylanilide C0049105 21889-00-9 T070521 5-chloro-3-tert-butyl-2'-nitrososalicylanilide C000415 2'-chloro-2'-cyanoethyl-1-thio-beta-D-galactopyranoside 1972 01 01 1982 11 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *GLYCOSIDES (72-74) *THIOGALACTOSIDES (75-82) *THIOGLYCOSIDES (74-75) *D009150 Mustard Compounds Nature (New Biology) 234(49):183;1971 NLM VSR NLM M0040520 2'-chloro-2'-cyanoethyl-1-thio-beta-D-galactopyranoside C0600827 Propanenitrile, 2-chloro-3-(beta-D-galactopyranosylthio)- 36373-29-2 T070522 2'-chloro-2'-cyanoethyl-1-thio-beta-D-galactopyranoside C000417 Ro 5-5807 1971 01 01 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *BENZAZEPINES (71-74) *D001570 Benzodiazepinones NLM NLM M0040521 Ro 5-5807 C0600828 7-chloro-2,3-dihydro-N-methyl-2-oxo-5- phenyl-lH-1-benzodiazepin-1-acetamide 2533-31-5 T070523 Ro 5-5807 C027236 Chwastox D 1980 12 09 2001 08 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 mixture of MCPA ; dicamba; RN given refers to parent cpd 2 *D003996 Dicamba *D008456 2-Methyl-4-chlorophenoxyacetic Acid D004338 Drug Combinations Gig Sanit 1982;(8):86 Med Pr 1980;31(3):177 MEG CCR CCR M0088702 Chwastox D C0055671 8003-31-4 8065-43-8 (Na salt) M0088702 M0088701 M0088702 M0317175 T118705 Chwastox D M0088701 Diamet-D C0113549 M0088702 M0088701 T118704 Diamet-D M0317175 Chwastox D, sodium salt C0954208 8065-43-8 M0088702 M0317175 T347175 Chwastox D, sodium salt 1999 08 18 C025121 apolipoprotein E-HDL(c) 1980 07 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 cholesterol-induced high density lipoprotein containing only E apoprotein 10 *APOLIPOPROTEINS (80-84) *D001057 Apolipoproteins E J Biol Chem 1980;255(11):5454 MEG WXM WXM M0084131 apolipoprotein E-HDL(c) C0052207 0 T114134 apolipoprotein E-HDL(c) T114133 apo E-HDL(c) C026452 messenger ribonucleoprotein 1980 10 09 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 167 *NUCLEOPROTEINS (80-81) *D012261 Ribonucleoproteins Biochemistry 1980;19(14):3164 RLS WXM WXM M0086860 messenger ribonucleoprotein C0066030 0 T116863 messenger ribonucleoprotein T116862 mRNP C113291 2-acetamido-2,6-dideoxy-glucose (N-acetyl-quinovosamine) 1998 07 28 2001 01 25 1998 1999 2000 2001 2001A 2002 a neutral Proteus penneri O-antigen 1 D000117 Acetylglucosamine *Q000031 analogs ; derivatives Eur J Biochem 1998 May 1;253(3):730-3 SZM CCR CCR M0292645 2-acetamido-2,6-dideoxy-glucose (N-acetyl-quinovosamine) C0754937 0 T322650 2-acetamido-2,6-dideoxy-glucose (N-acetyl-quinovosamine) T322648 2-acetamido-2,6-dideoxy-L-glucose (N-acetyl-L-quinovosamine) T322649 L-QuiNAc C114468 uridine 5'-(2-trifluoroacetamido-2-deoxyglucopyranosyl diphosphate) 1998 09 28 2001 01 25 1998 1999 2000 2001 2001A 2002 structure in first source 1 D000117 Acetylglucosamine *Q000031 analogs ; derivatives D014530 Uridine Diphosphate *Q000031 analogs ; derivatives Carbohydr Res 1998 Jan;306(1-2):127-36 THA CCR CCR M0295187 uridine 5'-(2-trifluoroacetamido-2-deoxyglucopyranosyl diphosphate) C0757471 0 T325192 uridine 5'-(2-trifluoroacetamido-2-deoxyglucopyranosyl diphosphate) T325190 UDP-GlcNAc-F(3) T325191 UDP-N-trifluoroacetylglucosamine C000443 1-(4-chlorophenyl)-1-phenyl-2-propynylcarbamate 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ALKYNES (72-76) *D002219 Carbamates Toxicology Applied Pharmacology 21(3):414;1972 NLM NLM M0040562 1-(4-chlorophenyl)-1-phenyl-2-propynylcarbamate C0600842 10473-70-8 T070564 1-(4-chlorophenyl)-1-phenyl-2-propynylcarbamate C082384 RNP1 protein 1993 08 27 2001 05 15 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 an acidic protein containing two highly conserved RNA-recognition motifs, associated with ribosomes; amino acid sequence given in first source 8 *D012269 Ribosomal Proteins *D016601 RNA-Binding Proteins D005656 Fungal Proteins D012441 Saccharomyces cerevisiae Nucleic Acids Res 1993 Jul 11;21(14):3211-6 BMB CCR CCR M0219535 RNP1 protein C0218549 0 T249540 RNP1 protein T249538 RNP1 gene product T249539 RNP1p C000455 5-chlorouridine 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 *URIDINE (72-75) CHLORINE (72-76) D014529 Uridine *Q000031 analogs ; derivatives Proc Natl Acad Sci 68(9):2008;1971 NLM NLM M0040576 5-chlorouridine C0049114 2880-89-9 T070578 5-chlorouridine C000458 N-acetyllactosamine 1972 01 01 1998 04 20 1998 1999 2000 2001 2002 RN given refers to D-isomer 188 LACTOSE (72-75) LACTOSE/analogs (75-81) *D000606 Amino Sugars J Biol Chem 247(12):3744;1972 NLM BQV NLM M0040577 N-acetyllactosamine C0067736 32181-59-2 T070579 N-acetyllactosamine C000461 N-bromoacetazolamide 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *ACETAZOLAMIDE (72-75) BROMINE (72-76) D000086 Acetazolamide *Q000031 analogs ; derivatives J Biol Chem 247(12):3810;1972 NLM NLM M0040579 N-bromoacetazolamide C0067855 17124-38-8 T070581 N-bromoacetazolamide C000463 carboxysulfmyoglobin 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *MYOGLOBIN (72-75) SULFUR (72-75) D009211 Myoglobin *Q000031 analogs ; derivatives J Biol Chem 247(12):3774;1972 NLM NLM M0040581 carboxysulfmyoglobin C0600845 0 T070583 carboxysulfmyoglobin C000464 caseidin 1972 01 01 1982 10 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 technetium labeled caseidin used for radioisotope scanning 0 *D010455 Peptides Nuclear Med 13(7):517;1972 NLM VSR NLM M0040582 caseidin C0600846 0 T070584 caseidin C000465 chainin 1972 01 01 1983 08 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *POLYENES (74-76) *D007783 Lactones J Am Chem Soc 94(12):4306;1972 NLM ACS NLM M0040583 chainin C0600847 2-(n-butyl)-16-methyl-3,5,7,9,11,13,15,26,27-nonahydroxyoctacosa-16,18,20,22,24-pentaenoic acid, 27-lactone 38264-25-4 T070585 chainin C000467 chelidimerine 1972 01 01 1981 06 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PHENANTHRIDINES (72-81) ACETONE (74-75) *D000470 Alkaloids J Natural Prod 35(1):87;1972 NLM NBM NLM M0040584 chelidimerine C0600848 1,3-bis(11-hydrosanquinarinyl)acetone 39110-99-1 T070586 chelidimerine C000480 Cibacron Blue-amylose 1974 01 01 1998 01 05 1998 1999 2000 2001 2002 0 *AMYLOSE (74-75) *ANTHRACENES (74-83) *D014227 Triazines D000688 Amylose *Q000031 analogs ; derivatives NLM IDX NLM M0040614 Cibacron Blue-amylose C0055703 0 T070616 Cibacron Blue-amylose C000482 cinerubine B 1972 01 01 1988 07 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 ANTHRACENES (72-83) NAPHTHACENES (71-88) *D015249 Antibiotics, Anthracycline Helvetica Chim Acta 55(2):467;1972 NLM RGM NLM M0040616 cinerubine B C0055743 35906-51-5 T070618 cinerubine B C000483 cinnabarinic acid 1970 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 13 CARBOXYLIC ACIDS (72-76) *D010078 Oxazines Biochem J 161(3):551;1977 Biochem Pharmacol 25(6):643;1976 Hoppe-Seyler's Z Physiol Chem 358:1161;1977 NLM NLM M0040617 cinnabarinic acid C0055751 2-amino-3H-phenoxazin-one-1,9-dicarboxylic acid 606-59-7 T070619 cinnabarinic acid C000484 4-hydroxy-3-methoxytriterpene cinnamate 1970 01 01 1982 10 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CINNAMATES (70-82) *TERPENES (70-74) *D014315 Triterpenes NLM VSR NLM M0040618 4-hydroxy-3-methoxytriterpene cinnamate C0600850 triterpene alcohol ester of ferulic acid 0 T070620 4-hydroxy-3-methoxytriterpene cinnamate C000497 codicaps 1971 01 01 1994 06 23 1995 1996 1997 1998 1999 2000 2001 2002 0 *D002744 Chlorpheniramine *D003061 Codeine D004338 Drug Combinations Arzneim Forsch 21(11):1692;1971 NLM MLH TPW M0040638 codicaps C0600854 Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-, mixt. with gamma-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine (Z)-2-butenedioate (1:1) 76095-56-2 T070640 codicaps C000509 corchoroside B 1972 01 01 1982 09 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CARDANOLIDES (72-77) GLYCOSIDES (72-82) *D002298 Cardenolides D002301 Cardiac Glycosides Helv Chim Acta 54(7):1960;1971 NLM VSR NLM M0040665 corchoroside B C0600856 35536-76-6 T070667 corchoroside B C000510 coriamyrtine 1972 01 01 1981 11 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 PLANT EXTRACTS (72-81) *D007783 Lactones Europ. J. Toxicol. 3(1):191;1970 NLM NBM NLM M0040666 coriamyrtine C0600857 2571-86-0 T070668 coriamyrtine Merck Index, 8th ed. p.285 C000535 cicliomenol 1971 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 *PHENOLS (71-75) CYCLOHEXANES (71-76) *D003408 Cresols NLM TWD TWD M0040704 cicliomenol C0600865 2-cyclohexyl-4-iodo-3,5-dimethylphenol 10572-34-6 M0040704 M0040703 T070706 cicliomenol Negwer, 4th ed, #96N USAN 1980, p. 74 M0040703 LV 267 C0600864 M0040704 M0040703 T070705 LV 267 C000672 Danaden retard 1972 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 contains pyrithioxine ; pyridylcarbinol tartrate 0 *PYRIDINES (72-75) *PYRIDOXINE (72-75) *D009540 Nicotinyl Alcohol *D011746 Pyrithioxin D004338 Drug Combinations D009440 Neurasthenia Q000188 drug therapy Z Allgemeinmed 48(7):344;1972 NLM TWD TWD M0040766 Danaden retard C0600886 3-Pyridinemethanol, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1) (salt), mixt. with 3,3'-(dithiobis(methylene))bis(5-hydroxy-6-methyl-4-pyridinemethanol) 76391-79-2 M0040766 M0040765 T070768 Danaden retard M0040765 EP 50/100 C0600885 M0040766 M0040765 T070767 EP 50/100 C000770 scopafungin 1972 01 01 2001 01 25 1999 2000 2001 2001A 2002 crystalline nonpolyenic antimicrobial agent from culture broth of Streptomyces hygroscopicus; no other info available 1/14/80 1 D007783 Lactones Appl Microbiol 22(3):303;1971 NLM TWD TWD M0040787 scopafungin C0074189 11056-18-1 M0040787 M0040786 T070789 scopafungin USAN 1978, p.280 M0040786 U-29,479 C0147497 M0040787 M0040786 T070788 U-29,479 C036027 L-fuculosephosphate aldolase 1982 11 01 2000 10 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 11 *D000446 Aldehyde-Lyases J Bacteriol 1982;152(1):120 VSR CCR CCR M0110012 L-fuculosephosphate aldolase C0207833 EC 4.1.2.17 T116 Amino Acid, Peptide, or Protein T126 Enzyme 9024-54-8 (CRN) T140016 L-fuculosephosphate aldolase T140015 L-fuculose-1-phosphate aldolase C000521 cutin 1971 01 01 1982 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 Cutin is meshwork of polymerized cross-esterified hydroxy fatty acids found in plant cuticles 35 *LIPIDS (71-78) FATTY ACIDS (71-75) HYDROXY ACIDS (71-82) POLYMERS (71-79) *D008563 Membrane Lipids Arch Biochem Biophys 190(1):17;1978 Biochem Soc 5(5):1263;1977 J Agr Food Chem 26(5):1263;1978 J Bacteriol 133(2):942;1978 NLM NBM NLM M0040694 cutin C0056618 Cutin 54990-88-4 T070696 cutin C000517 crotarbital 1972 01 01 2000 07 31 2001 2002 RN given refers to parent cpd without isomeric designation 7 *BARBITURATES (72-79) BUTABARBITAL/*analogs(80-94) CROTONATES (72-82) *D001463 Barbiturates Z Arztl Fortbild 72(16):769;1978 NLM CCR sjn M0040687 crotarbital C0056520 1952-67-6 T109 Organic Chemical T121 Pharmacologic Substance 28360-89-6 ((E)-isomer) 2933-25-7 (Na salt) M0040687 M0307458 M0040687 M0307459 T070689 crotarbital Negwer, 5th ed, #1363 T070685 5-ethyl-5-crotylbarbituric acid T070686 calypnon T070687 crotylbarbital T070688 krotylbarbital M0307458 crotarbital, (E)-isomer C0893884 28360-89-6 T109 Organic Chemical T121 Pharmacologic Substance M0040687 M0307458 T337458 crotarbital, (E)-isomer 1999 08 18 M0307459 crotarbital, sodium salt C0917106 2933-25-7 T109 Organic Chemical T121 Pharmacologic Substance M0040687 M0307459 T337459 crotarbital, sodium salt 1999 08 18 C005661 beta,beta-difluoroamphetamine 1974 01 01 2000 07 31 2001 2002 RN given refers to parent cpd; structure 0 *AMPHETAMINE (74-75) AMPHETAMINE/*analogs (75-78) *D000662 Amphetamines Biochem Pharmacol 22(16):2059;1973 NLM TWD sjn M0047331 beta,beta-difluoroamphetamine C0602291 39038-72-7 T109 Organic Chemical T121 Pharmacologic Substance 35651-89-9 (HCl(+-)-isomer) M0047331 M0309192 T077334 beta,beta-difluoroamphetamine M0309192 beta,beta-difluoroamphetamine, hydrochloride(+-)-isomer C0894834 35651-89-9 M0047331 M0309192 T339192 beta,beta-difluoroamphetamine, hydrochloride(+-)-isomer 1999 08 18 C000531 cycloheptamycin 1971 01 01 1994 04 15 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 PEPTIDES (71-79) PEPTIDES, CYCLIC (80-94) *D017561 Antibiotics, Peptide NLM BMB NLM M0040698 cycloheptamycin C0600860 30270-78-1 T070700 cycloheptamycin C000533 cyclohexadiene-1,2-diol-1-carboxylic acid 1971 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 HYDROXY ACIDS (75-76) *D003509 Cyclohexanecarboxylic Acids Biochim Biophys Acta 542(3):424;1978 NLM NLM M0040699 cyclohexadiene-1,2-diol-1-carboxylic acid C0056754 32359-20-9 T070701 cyclohexadiene-1,2-diol-1-carboxylic acid C049958 6-O-(3-hydroxy-2-docosylhexacosanoyl)muramyl dipeptide 1986 10 14 2001 01 25 1996 1997 1998 1999 2000 2001 2001A 2002 1 D000119 Acetylmuramyl-Alanyl-Isoglutamine *Q000031 analogs ; derivatives Infect Immunol 1986;53(3):517 RLS CCR CCR M0142913 6-O-(3-hydroxy-2-docosylhexacosanoyl)muramyl dipeptide C0628491 81649-55-0 T172918 6-O-(3-hydroxy-2-docosylhexacosanoyl)muramyl dipeptide T172916 6-O-(3-hydroxy-2-docosylhexacosanoyl)-N-acetylmuramyl-L-alanyl-D-isoglutamine T172917 BH48-MDP C060520 N-palmitoylmuramyl-alanyl-isoglutamine 1989 08 30 2001 01 25 1996 1997 1998 1999 2000 2001 2001A 2002 2 D000119 Acetylmuramyl-Alanyl-Isoglutamine *Q000031 analogs ; derivatives Jpn J Exp Med 1988;58(6):243 TPW CCR CCR M0168121 N-palmitoylmuramyl-alanyl-isoglutamine C0068261 78408-99-8 T198126 N-palmitoylmuramyl-alanyl-isoglutamine T198124 N-PA-Mur-Ala-isoGln T198125 NP-MDP C000857 deca-glycerol deca-oleate 1972 01 01 2001 01 25 1998 1999 2000 2000A 2001 2001A 2002 polyglycerol ester 0 *GLYCEROL (72-75) *POLYMERS (72-75) OLEIC ACIDS (75-82) D005990 Glycerol *Q000031 analogs ; derivatives Toxicol Appl Pharmacol 20(3):327;1971 NLM TWD TWD M0040814 deca-glycerol deca-oleate C0600897 9-Octadecenoic acid (Z)-, decaester with decaglycerol 11094-60-3 M0040814 M0040813 T070816 deca-glycerol deca-oleate M0040813 Drewpol C0600896 M0040814 M0040813 T070815 Drewpol C000539 cyclonerodiol 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CYCLOPENTANES (75-76) *D012717 Sesquiterpenes NLM NLM M0040707 cyclonerodiol C0600866 28834-06-2 T070709 cyclonerodiol C000869 demoxepam 1972 01 01 2001 01 25 1999 2000 2001 2001A 2002 structure 11 *BENZAZEPINES (72-74) *TRANQUILIZING AGENTS (72-75) CYCLIC N-OXIDES (74-75) *D001568 Anti-Anxiety Agents, Benzodiazepine J Chromatogr 146(3):473;1978 J Pharm Sci 61(1):123;1972 J Pharm Sci 65(8):1198;1976 J Pharm Sci 66(6):684;1977 NLM TWD TWD M0040836 demoxepam C0057377 7-chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 4-oxide 963-39-3 M0040836 M0040835 T070838 demoxepam M0040835 Ro 5-2092 C0140790 M0040836 M0040835 T070837 Ro 5-2092 C000544 N-cyclopropylmethyl oripavine 1972 01 01 1989 06 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 D013797 Thebaine *Q000031 analogs ; derivatives D003521 Cyclopropanes D009019 Morphinans Brit J Pharmacol 43(2):461P;1971 NLM TPW NLM M0040717 N-cyclopropylmethyl oripavine C0600867 0 T070719 N-cyclopropylmethyl oripavine C000545 cygerol 1971 01 01 1982 02 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *FATTY ACIDS, UNSATURATED (73-79) CYCLOHEXANES (71-82) FATTY ACIDS (71-73) *D013729 Terpenes NLM NBM NLM M0040720 cygerol C0056837 cyclohexyl-4,9-dimethyl-4,8-decadienoic acid 27783-27-3 M0040720 M0040719 M0040720 M0040718 T070722 cygerol M0040719 Cigerol C0109784 M0040720 M0040719 T070721 Cigerol M0040718 2-cyclohexyl-2-geranylacetic acid C0092842 M0040720 M0040718 T070720 2-cyclohexyl-2-geranylacetic acid C000552 rubrosterone 1972 01 01 1982 08 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ANDROSTANES (72-80) HYDROXYSTEROIDS (73-76) *D000732 Androstanols *D015068 17-Ketosteroids D007447 Invertebrate Hormones J Pharm Soc Jpn 91(9):916;1971 NLM VSR NLM M0040723 rubrosterone C0073701 19466-41-2 T070725 rubrosterone C000553 9-(3-(cytos-1-yl)propyl)-2-dimethylaminopurin-6-one 1970 01 01 1982 10 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CYTOSINE (70-75) *PURINONES (70-82) DIMETHYLAMINES (73-75) D003596 Cytosine *Q000031 analogs ; derivatives NLM VSR NLM M0040724 9-(3-(cytos-1-yl)propyl)-2-dimethylaminopurin-6-one C0600868 28098-44-4 T070726 9-(3-(cytos-1-yl)propyl)-2-dimethylaminopurin-6-one C000578 exo-bicyclo(3.1.0)hexane-6-carboxylic acid 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 BICYCLO COMPOUNDS (75-76) *D003509 Cyclohexanecarboxylic Acids J Med Chem 15(4):424;1972 NLM NLM M0040731 exo-bicyclo(3.1.0)hexane-6-carboxylic acid C0600872 4971-24-8 T070733 exo-bicyclo(3.1.0)hexane-6-carboxylic acid C000653 anhydrochymotrypsin 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 4 *D002918 Chymotrypsin J Mol Biol 67(2):247;1972 NLM NLM M0040733 anhydrochymotrypsin C0051898 0 T070735 anhydrochymotrypsin C054064 N-acetylmuramyl-threonyl-isoglutamine 1987 12 11 2001 01 25 1996 1997 1998 1999 2000 2001 2001A 2002 7 D000119 Acetylmuramyl-Alanyl-Isoglutamine *Q000031 analogs ; derivatives Vaccine 1987;5(3):223 MGR CCR CCR M0152879 N-acetylmuramyl-threonyl-isoglutamine C0067759 66112-59-2 M0152879 M0152877 T182884 N-acetylmuramyl-threonyl-isoglutamine T182883 THR-MDP M0152877 SAF-m C0245252 M0152879 M0152877 T182882 SAF-m C000660 chloroquine diorotate 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CHLOROQUINE (72-75) OROTIC ACID (72-75) D002738 Chloroquine *Q000031 analogs ; derivatives Med Biol(Jap) 84(1):33;1972 NLM NLM M0040743 chloroquine diorotate C0600878 16301-30-7 T070745 chloroquine diorotate C000896 NSC 102722 1971 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 *UREA (71-75) ALLYL COMPOUNDS (73-82) D014508 Urea *Q000031 analogs ; derivatives NLM TWD TWD M0040867 NSC 102722 C0600909 1,3-diallylurea 1801-72-5 T070869 NSC 102722 T070868 NSC-102722 C000668 5-carboxymethyluridine 1972 01 01 1981 08 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *URIDINE (72-75) CARBOXYLIC ACIDS (72-75) D014529 Uridine *Q000031 analogs ; derivatives Biochim Biophys Acta 262(3):275;1972 Biochim Biophys Acta 518:530;1978 NLM NBM NLM M0040758 5-carboxymethyluridine C0049099 20964-06-1 T070760 5-carboxymethyluridine C068282 N-(2-O-(2-acetamido-1,2,3,5-tetradeoxy-1,5-iminoglucitol-3-yl)lactoyl)alanyl-isoglutamine 1991 05 13 2001 01 25 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 D000119 Acetylmuramyl-Alanyl-Isoglutamine *Q000031 analogs ; derivatives Carbohydr Res 1990;208:267 RLS CCR CCR M0186814 N-(2-O-(2-acetamido-1,2,3,5-tetradeoxy-1,5-iminoglucitol-3-yl)lactoyl)alanyl-isoglutamine C0645223 131432-97-8 T216819 N-(2-O-(2-acetamido-1,2,3,5-tetradeoxy-1,5-iminoglucitol-3-yl)lactoyl)alanyl-isoglutamine T216817 ATIGLAI T216818 N-(2-O-(2-acetamido-1,2,3,5-tetradeoxy-1,5-imino-D-glucitol-3-yl)-D-lactoyl)-L-alanyl-D-isoglutamine C001265 fumaropimaric acid 1974 01 01 2000 07 31 2001 2002 RN given refers to (4alpha,8alpha,12alpha,13R,14S)-isomer 1 FURMARATES (74-82) *D004224 Diterpenes NLM CCR sjn M0041379 fumaropimaric acid C0060827 125-66-6 T109 Organic Chemical 63179-62-4 (di-Na salt (4alpha,8alpha,12alpha,13R,14R)-isomer) M0041379 M0307586 T071382 fumaropimaric acid M0307586 fumaropimaric acid, disodium salt, (4alpha,8alpha,12alpha,13R,14R)-isomer C0893972 63179-62-4 T109 Organic Chemical M0041379 M0307586 T337586 fumaropimaric acid, disodium salt, (4alpha,8alpha,12alpha,13R,14R)-isomer 1999 08 18 C000899 3-hydroxycadaverine 1972 01 01 2001 01 25 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 *AMINO ALCOHOLS (74-75) *POLYAMINES (72-74) D002103 Cadaverine *Q000031 analogs ; derivatives Enzymologia 42(4):303;1972 NLM TWD TWD M0040872 3-hydroxycadaverine C0600914 38595-00-5 T070874 3-hydroxycadaverine T070873 1,5-diamino-3-pentanol C000674 datiscoside 1972 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CHOLESTANES (72-73) *CHOLESTENES (73-74) *GLYCOSIDES (72-82) *D002775 Cholestadienols J Am Chem Soc 94(4):1353;1972 NLM VSR NLM M0040768 datiscoside C0600888 36067-56-8 T070770 datiscoside C000886 Dexa-Rhinospray 1971 01 01 2002 03 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 2002A combination drug; contains Tyzanol, the pyridine carboxylate of dexamethasone ; neomycin sulfate 0 *DEXAMETHASONE (71-75) *D007093 Imidazoles *D009355 Neomycin D003907 Dexamethasone *Q000031 analogs ; derivatives D004338 Drug Combinations D006255 Hay Fever Q000188 drug therapy NLM TWD TWD M0040860 Dexa-Rhinospray C0057587 0 T109 Organic Chemical T121 Pharmacologic Substance M0040860 M0040859 T070862 Dexa-Rhinospray M0040859 K47a Rhi C0124414 T109 Organic Chemical T121 Pharmacologic Substance M0040860 M0040859 T070861 K47a Rhi C000795 StC 407 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *HYDROCORTISONE (72-74) *PREGNADIENETRIOLS (74-75) D006854 Hydrocortisone *Q000031 analogs ; derivatives Arzneim Forsch 21(10):1510;1971 NLM NLM M0040789 StC 407 C0075194 6-dehydro-16-methylene hydrocortisone 17332-61-5 T070791 StC 407 C047255 matrix Gla protein 1986 01 02 2002 03 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2001B 2002 2002A 79-residue, vitmin K-dependent protein; different from bone Gla protein; contains single disulfide bond ; 4.8 gamma-carboxyglutamate (Gla) residues 122 *D002135 Calcium-Binding Proteins D001842 Bone and Bones D014812 Vitamin K D015055 1-Carboxyglutamic Acid J Biol Chem 1985;260(28):14971 RLS CCR CCR M0136588 matrix Gla protein C0065752 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance M0136588 M0136587 T166593 matrix Gla protein T465966 MGP protein 2001 10 13 T166591 Gla protein, matrix T465967 matrix gamma-carboxyglutamic acid protein 2001 10 13 M0136587 bovine matrix Gla protein C0208286 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance M0136588 M0136587 T166592 bovine matrix Gla protein C001300 gamma-glutamine-4-nitroanilide 1972 01 01 2000 07 31 2001 2002 substrate for glutaminase B.; RN given refers to (L)-isomer 31 *ANILIDES (72-82) *GLUTAMATES (72-89) NITRO COMPOUNDS (72-76) D005973 Glutamine *Q000031 analogs ; derivatives BBA 483:46;1977 BBA 483:57;1977 Biochem Biophys Res Commun 46(3):1278;1972 Clin Chim Acta 78(3):503;1977 NLM CCR sjn M0041420 gamma-glutamine-4-nitroanilide C0061046 7300-59-6 T116 Amino Acid, Peptide, or Protein 67953-08-6 (mono-HCl(L)-isomer) M0041420 M0041417 M0041420 M0041418 M0041420 M0307592 T071423 gamma-glutamine-4-nitroanilide T071422 gamma-glutamyl-4-nitroanilide M0041417 D-gamma-glutamyl-4-nitroanilide C0112101 T116 Amino Acid, Peptide, or Protein M0041420 M0041417 T071420 D-gamma-glutamyl-4-nitroanilide M0041418 L-gamma-glutamyl-p-nitroanilide C0125011 T116 Amino Acid, Peptide, or Protein M0041420 M0041418 T071421 L-gamma-glutamyl-p-nitroanilide M0307592 gamma-glutamine-4-nitroanilide, monohydrochloride, (L)-isomer C0893975 67953-08-6 T116 Amino Acid, Peptide, or Protein M0041420 M0307592 T337592 gamma-glutamine-4-nitroanilide, monohydrochloride, (L)-isomer 1999 08 18 C000852 3-deazacytidine 1972 01 01 1997 08 14 1998 1999 2000 2001 2002 structure 5 *CYTIDINE (72-75) PYRIDINES (72-76) D003562 Cytidine *Q000031 analogs ; derivatives D003564 Cytidine Deaminase Q000037 antagonists ; inhibitors Biochem Pharmacol 21(8):1063;1972 NLM MLH TPW M0040810 3-deazacytidine C0047331 28307-19-9 T070812 3-deazacytidine C000862 dehydrocapaurimine 1970 01 01 1998 05 14 1998 1999 2000 2001 2002 structure; RN given refers to chloride 0 QUINOLIZINES (70-81) *D000470 Alkaloids NLM BQV NLM M0040822 dehydrocapaurimine C0600899 Dibenzo(a,g)quinolizinium, 5,6-dihydro-1,10-dihydroxy-2,3,9-trimethoxy-, chloride 57499-40-8 T070824 dehydrocapaurimine C000864 dehydrosqualene 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 4 *SQUALENE (72-75) D013185 Squalene *Q000031 analogs ; derivatives Biochem Biophys Res Commun 85(3):867;1978 Biochim Biophys Acta 260(3):482;1972 NLM NLM M0040826 dehydrosqualene C0057294 11051-27-7 T070828 dehydrosqualene C000866 5-demethoxyubiquinone-9 1972 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 intermediate in biosynthesis of ubiquinone 1 *UBIQUINONE (72-75) D014451 Ubiquinone *Q000031 analogs ; derivatives J Biol Chem 247(8):2499;1972 NLM VSR NLM M0040827 5-demethoxyubiquinone-9 C0600900 7200-28-4 T070829 5-demethoxyubiquinone-9 C000874 deoxynybomycin 1970 01 01 1993 07 08 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 PYRIDINES (70-75) QUINOLINES (70-88) D015363 Quinolones NLM BXB TPW M0040842 deoxynybomycin C0057451 6,8,11-trimethyl-2H,4H-oxazolo(5,4,3-IJ)pyrido(3,2-g)quinoline-4,10(11H)-dione 27259-98-9 T070844 deoxynybomycin Merck Index, 9th ed, p. 874, in #6543 C047272 3-(N-maleimidopropionyl)biocytin 1986 01 07 2002 03 05 1998 1999 2000 2001 2001A 2002 2002A thiol-specific biotinylating reagent; structure given in first source 15 *D008301 Maleimides D008239 Lysine *Q000031 analogs ; derivatives Anal Biochem 1985;149(2):529 RLS CCR CCR M0136621 3-(N-maleimidopropionyl)biocytin C0047177 98930-71-3 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T166626 3-(N-maleimidopropionyl)biocytin T166624 3-(N-maleimido-propionyl)biocytin T166625 3-MPB C448581 IMAP protocol 2002 03 05 2002 a chemotherapy protocol consisting of the above compounds; used in the treatment of primary extremity soft tissue sarcomas 1 *D000971 Antineoplastic Combined Chemotherapy Protocols D002945 Cisplatin D004317 Doxorubicin D007069 Ifosfamide D016685 Mitomycin Cancer 2002 Feb 1;94(3):786-92 SZM SZM M0416571 IMAP protocol 0 T061 Therapeutic or Preventive Procedure T484543 IMAP protocol 2002 03 05 C047285 8,9-dihydro-8-(S-glutathionyl)-9-hydroxyaflatoxin B1 1986 01 10 2002 03 05 1997 1998 1999 2000 2001 2001A 2002 2002A structure given in first source 4 *AFLATOXINS (86-91) D005978 Glutathione *Q000031 analogs ; derivatives D016604 Aflatoxin B1 *Q000031 analogs ; derivatives Chem Biol Interact 1985;55(1-2):139 RLS CCR CCR M0136652 8,9-dihydro-8-(S-glutathionyl)-9-hydroxyaflatoxin B1 C0100074 68385-50-2 T109 Organic Chemical T166657 8,9-dihydro-8-(S-glutathionyl)-9-hydroxyaflatoxin B1 T166653 8,9-dihydro-8-(S-glutathionyl)-9-hydroxyaflatoxin B(1) T166654 8,9-dihydro-9-hydroxy-8-(S-glutathionyl)aflatoxin B1 T166655 AFB(1)-GSH T166656 AFB1-GSH conjugate C000882 desoxybilianic acid 1971 01 01 1982 07 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *BILE ACIDS AND SALTS (71-75) SECOSTEROIDS (71-82) D003840 Deoxycholic Acid *Q000031 analogs ; derivatives NLM CHA NLM M0040856 desoxybilianic acid C0600902 438-06-2 T070858 desoxybilianic acid C000884 detensitral 1971 01 01 1990 07 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains rescinnamine, paraflutizide, a morpholine compound, folescutol ; meprobamate 0 RESCINNAMINE (71-82) *D001581 Benzothiadiazines *D008620 Meprobamate *D009025 Morpholines D004338 Drug Combinations NLM SXR NLM M0040857 detensitral C0057573 Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-, mixt. with 6-chloro-3-((4-fluorophenyl)methyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6,7-dihydroxy-4-(4-morpholinylmethyl)-2H-1-benzopyran-2-one hydrochloride and 2-methyl-2-propyl-1,3-propanediyl dicarbamate 76448-26-5 T070859 detensitral C000885 dexa-phebrocon 1971 01 01 1986 07 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains dexamethasone, dequalinium chloride, cetylpyridinium chloride and dioxyphenylhexane; used as an antifungal or anti-inflammatory agent 0 *PYRIDINIUM CPDS (71-75) *QUINOLINIUM CPDS (71-76) *D002594 Cetylpyridinium *D003868 Dequalinium *D003907 Dexamethasone *D010636 Phenols D004338 Drug Combinations NLM THA NLM M0040858 dexa-phebrocon C0600903 0 T070860 dexa-phebrocon C086739 14-deacetylnudicauline 1994 05 11 2001 01 25 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a toxic alkaloid from tall larkspur Delphinium barbeyi 1 D000157 Aconitine *Q000031 analogs ; derivatives D010936 Plant Extracts Vet Hum Toxicol 1994 Feb;36(1):10-4 PML CCR CCR M0229921 14-deacetylnudicauline C0253746 119347-24-9 T259926 14-deacetylnudicauline T259924 14-DAN T259925 14-deacetyl-nudicauline C000889 diabtyl 1972 01 01 1982 07 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination of heparin ; enzymatic fraction of extract from venom of Bothrops atrox used in treatment of diabetic retinopathies 0 VENOMS (72-75) *D004798 Enzymes *D006493 Heparin *D012910 Snake Venoms D004338 Drug Combinations Therapeutique 47(9):801;1971 NLM CHA NLM M0040861 diabtyl C0057667 Diabtyl 76481-55-5 T070863 diabtyl C000893 diacetylthiamine 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *THIAMINE (72-75) D013831 Thiamine *Q000031 analogs ; derivatives J Vitaminol 17(3):135;1971 NLM NLM M0040862 diacetylthiamine C0600904 299-89-8 T070864 diacetylthiamine C042111 C 205 1984 09 05 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd 1 *D000166 Acridines Cancer Lett 1984;23(3):273 MGR CCR CCR M0124554 C 205 C0621894 6237-29-2 6237-28-1 (dihydrochloride) M0124554 M0321707 T154559 C 205 T154558 C-205 M0321707 C 205, dihydrochloride C0956460 6237-28-1 M0124554 M0321707 T351707 C 205, dihydrochloride 1999 08 18 C047402 2'-O-anthraniloyl AMP 1986 01 08 2002 03 05 1996 1997 1998 1999 2000 2001 2001A 2002 2002A 2 *D000879 Anthranilic Acids D000249 Adenosine Monophosphate *Q000031 analogs ; derivatives Anal Biochem 1985;149(1):202 MEG CCR CCR M0136917 2'-O-anthraniloyl AMP C0377879 98033-20-6 T114 Nucleic Acid, Nucleoside, or Nucleotide T130 Indicator, Reagent, or Diagnostic Aid T166922 2'-O-anthraniloyl AMP T166919 2'-O-anthraniloyl adenosine monophosphate T166920 ANT-AMP T166921 anthraniloyl-2'-AMP C000902 2,5-diaminotropone 1972 01 01 1994 06 27 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 AMINES (72-76) DIAMINES (72-82) KETONES (72-74) *D003508 Cycloheptanes J Pharm Soc Japan 91(12):1307;1971 NLM MLH TPW M0040876 2,5-diaminotropone C0600915 36039-40-4 T070878 2,5-diaminotropone C000906 6,12-diazaanthanthrene 1972 01 01 1983 08 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN given refers to parent cpd; structure 0 *D000166 Acridines Neoplasma 18(6):591;1971 NLM JSL NLM M0040883 6,12-diazaanthanthrene C0600917 acridino(2,1,9,8-klmna)acridine 191-27-5 34494-09-2 (sulfate) M0040883 M0307498 T070885 6,12-diazaanthanthrene M0307498 sulfate of 6,12-diazaanthanthrene C0893913 34494-09-2 M0040883 M0307498 T337498 sulfate of 6,12-diazaanthanthrene 1999 08 18 C006108 C 541 1975 01 01 2001 01 25 1998 1999 2000 2001 2001A 2002 RN ; NM refer to HCl; structure 0 ETHYLAMINES (75-82) *D000166 Acridines Arch Immunol Ther Exp (Warsz) 22(6):823;1974 Arch Immunol Ther Exp (Warsz) 22(6):843;1974 NLM CCR CCR M0048229 C 541 C0054373 10-(2-(dimethylamino)ethyl)-1-nitro-9(10H)-acridinone, monohydrochloride 24268-87-9 M0048229 M0048227 T078232 C 541 T078231 C-541 M0048227 1-nitro-10-(dimethylaminoethyl)-9-acridone.HCl C0089621 M0048229 M0048227 T078230 1-nitro-10-(dimethylaminoethyl)-9-acridone.HCl C000910 diazobenzenesulfonamide benzenesulfonate 1971 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *SULFONAMIDES (71-82) AZO CPDS (71-79) BENZENESULFONATES (74-76) *D003979 Diazonium Compounds NLM VSR NLM M0040888 diazobenzenesulfonamide benzenesulfonate C0600918 29733-04-8 T070890 diazobenzenesulfonamide benzenesulfonate C009969 10-(2-triethylaminoethyl)-9-acridone iodide 1975 01 01 2001 02 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 DIETHYLAMINES (75-80) *D000166 Acridines J Pharmacol Exp Ther 192(3):654;1975 NLM CCR CCR M0055109 10-(2-triethylaminoethyl)-9-acridone iodide C0089937 N,N,N-triethyl-9-oxo-10(9H)-acridineethanaminium, iodide 55011-84-2 M0055109 M0055111 T085112 10-(2-triethylaminoethyl)-9-acridone iodide M0055111 M-231 C0065443 M0055109 M0055111 T085114 M-231 T085113 M 231 C000914 dibenzocycloheptadiene 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *D003986 Dibenzocycloheptenes NLM NLM M0040900 dibenzocycloheptadiene C0243201 833-48-7 T070902 dibenzocycloheptadiene C000915 dibenzocycloheptatriene 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D003986 Dibenzocycloheptenes NLM NLM M0040901 dibenzocycloheptatriene C0600919 256-81-5 T070903 dibenzocycloheptatriene C000926 3,4-dichloro-N,N-di-sec-butylbenzamide 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D001549 Benzamides NLM NLM M0040914 3,4-dichloro-N,N-di-sec-butylbenzamide C0600924 27891-15-2 T070916 3,4-dichloro-N,N-di-sec-butylbenzamide C001003 N,N-diisopropyl-N'-isoamyl-N'-diethylaminoethylurea 1972 01 01 2001 07 26 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 inhibits adrenal uptake ; release of catecholamines; do not confuse with P-286, EN for Ioxaglic Acid; RN given refers to parent cpd; structure 3 *UREA (72-75) ETHYLAMINES (72-76) D014508 Urea *Q000031 analogs ; derivatives Adv Biochem Psychopharmacol 1(0):82;1969 NLM CCR CCR M0041030 N,N-diisopropyl-N'-isoamyl-N'-diethylaminoethylurea C0129935 N-(2-(diethylamino)ethyl)-N-(3-methylbutyl)-N',N'-bis(1-methylethyl)urea 54-54-6 1926-91-6 (HCl) M0041030 M0041033 M0041030 M0307521 T071033 N,N-diisopropyl-N'-isoamyl-N'-diethylaminoethylurea M0041033 P 286 (pharmaceutical) C0282707 M0041030 M0041033 T071036 P 286 (pharmaceutical) T071034 P-286 (pharmaceutical) T071035 P286 (pharmaceutical) M0307521 N,N-diisopropyl-N'-isoamyl-N'-diethylaminoethylurea hydrochloride C0951020 1926-91-6 M0041030 M0307521 T337521 N,N-diisopropyl-N'-isoamyl-N'-diethylaminoethylurea hydrochloride 1999 08 18 C055378 cholinium 9-oxo-10-acridineacetate 1988 05 02 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd 1 *D000166 Acridines Arch Immunol Ther Exp (Warsz) 1987;35(3):389 TPW CCR CCR M0155934 cholinium 9-oxo-10-acridineacetate C0633258 108119-59-1 108119-60-4 (chloride) M0155934 M0323630 T185939 cholinium 9-oxo-10-acridineacetate T185938 CSCMA M0323630 cholinium 9-oxo-10-acridineacetate chloride C0957563 108119-60-4 M0155934 M0323630 T353630 cholinium 9-oxo-10-acridineacetate chloride 1999 08 18 C001070 diniprofylline 1972 01 01 2001 01 25 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 *NICOTINIC ACIDS (75-82) *THEOPHYLLINE (72-75) PROPANEDIOLS (74-76) THEOPHYLLINE/*analogs (75-80) D004400 Dyphylline *Q000031 analogs ; derivatives J Med Lyon 52(2-6):535;1971 NLM TWD TWD M0041157 diniprofylline C0600993 7-((2,3-dihydroxypropyl)theophylline bisnicotinate ester) 17692-30-7 M0041157 M0041156 T071160 diniprofylline M0041156 Corverum C0600992 M0041157 M0041156 T071159 Corverum C000947 dicyclohexylammonium-2-(4-(N,N-bis(2-chloroethyl)amino) phenoxy)-2-methylpropionate 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 PHENYL ETHERS (74-76) *D009588 Nitrogen Mustard Compounds D011422 Propionates J Med Chem 15(4):436;1972 NLM NLM M0040946 dicyclohexylammonium-2-(4-(N,N-bis(2-chloroethyl)amino) phenoxy)-2-methylpropionate C0600932 Propanoic acid, 2-(4-(bis(2-chloroethyl)amino)phenoxy)-2-methyl-, compd. with N-cyclohexylcyclohexanamine (1:1) 34919-66-9 T070948 dicyclohexylammonium-2-(4-(N,N-bis(2-chloroethyl)amino) phenoxy)-2-methylpropionate C000951 diethylamino-2-butynylsuccinimide 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 DIETHYLAMINES (74-76) *D013388 Succinimides NLM NLM M0040948 diethylamino-2-butynylsuccinimide C0057940 7591-19-7 T070950 diethylamino-2-butynylsuccinimide C000966 Dihydrodigitoxin 1971 01 01 1980 03 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 *DIGITOXIN (71-75) D004074 Digitoxin *Q000031 analogs ; derivatives Naunyn Schmiedebergs Arch Pharmacol 1979;310(2):147 NLM MEG NLM M0040979 Dihydrodigitoxin C0058064 3786-76-3 T070981 Dihydrodigitoxin C001084 cetylphenylbutazone 1971 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 *PHENYLBUTAZONE (71-75) D010653 Phenylbutazone *Q000031 analogs ; derivatives NLM TWD TWD M0041175 cetylphenylbutazone C0600996 3,5-Pyrazolidinedione, 4-(3-methylnonadecyl)-1,2-diphenyl- 56866-34-3 T071178 cetylphenylbutazone T071177 1,2-diphenyl-3,5-dioxo-4-(gamma-cetobutyl)pyrazoline C000969 2,3-dihydrohelenalin 1972 01 01 1980 10 23 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *TERPENES (72-74) LACTONES (72-76) *D012717 Sesquiterpenes J Med Chem 15(6):609;1972 NLM RLS NLM M0040981 2,3-dihydrohelenalin C0600944 35412-73-8 T070983 2,3-dihydrohelenalin C000978 dihydropteroate 1972 01 01 1979 11 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 5 *D011622 Pterins J Nutr Sci Vit 22(3):365;1976 Tropenmed Parasitol 22(3):256;1971 NLM PLS NLM M0040992 dihydropteroate C0058104 4-(((2-amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl)amino)benzoic acid 2134-76-1 T070994 dihydropteroate C001090 acetylenic carbamate 1971 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 ALKYNES (71-76) CYCLOHEXANES (71-76) *D002219 Carbamates Cancer Chemother Rep 54(2):131;1970 NLM TWD TWD M0041183 acetylenic carbamate C0050514 1,1-diphenyl-2-propynyl cyclohexylcarbamate 10087-89-5 M0041183 M0041182 T071186 acetylenic carbamate M0041182 NSC-112682 C0133104 M0041183 M0041182 T071185 NSC-112682 C001179 AL 1612 1972 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 DIOXOLES (72-76) PIPERIDINES (72-81) *D007211 Indoles Curr Ther Res 13(9):584;1971 Res Commun Chem Pathol Pharmacol 23(1):61;1979 NLM TWD TWD M0041283 AL 1612 C0051046 3-ethyl-6,7-dihydro-2-methyl-5-(4,4-ethylenedioxypiperidinomethyl)indole-4(5H)-one 25331-92-4 T071286 AL 1612 T071285 AL-1612 C001014 2,5-dimethoxy-4-ethylamphetamine 1971 01 01 2000 07 31 2001 2002 psychedelic agent; ethyl homolog of dimethoxymethylamphetamine; RN given refers to parent cpd without isomeric designation 2 *AMPHETAMINE (71-75) METHYL ETHERS (72-76) D004290 2,5-Dimethoxy-4-Methylamphetamine *Q000031 analogs ; derivatives Arch Gen Psychiatry 24:50;1971 Arch Gen Psychiatry 31:103;1974 NLM CCR sjn M0041050 2,5-dimethoxy-4-ethylamphetamine C0045562 22004-32-6 T109 Organic Chemical T121 Pharmacologic Substance 22139-65-7 (HCl) 41538-40-3 ((+-)-isomer) 42011-76-7 (HCl(R)-isomer) 50505-91-4 (HCl(S)-isomer) 53305-83-2 ((S)-isomer) 53581-54-7 (HCl(+-)-isomer) 57116-37-7 ((R)-isomer) M0041050 M0307523 M0041050 M0307528 M0041050 M0307526 M0041050 M0307522 M0041050 M0307527 M0041050 M0307524 M0041050 M0307525 T071053 2,5-dimethoxy-4-ethylamphetamine M0307523 2,5-dimethoxy-4-ethylamphetamine, (+-)-isomer C0893927 41538-40-3 T109 Organic Chemical T121 Pharmacologic Substance M0041050 M0307523 T337523 2,5-dimethoxy-4-ethylamphetamine, (+-)-isomer 1999 08 18 M0307528 2,5-dimethoxy-4-ethylamphetamine, (R)-isomer C0893932 57116-37-7 T109 Organic Chemical T121 Pharmacologic Substance M0041050 M0307528 T337528 2,5-dimethoxy-4-ethylamphetamine, (R)-isomer 1999 08 18 M0307526 2,5-dimethoxy-4-ethylamphetamine, (S)-isomer C0893930 53305-83-2 T109 Organic Chemical T121 Pharmacologic Substance M0041050 M0307526 T337526 2,5-dimethoxy-4-ethylamphetamine, (S)-isomer 1999 08 18 M0307522 2,5-dimethoxy-4-ethylamphetamine, hydrochloride C0893926 22139-65-7 T109 Organic Chemical T121 Pharmacologic Substance M0041050 M0307522 T337522 2,5-dimethoxy-4-ethylamphetamine, hydrochloride 1999 08 18 M0307527 2,5-dimethoxy-4-ethylamphetamine, hydrochloride, (+-)-isomer C0893931 53581-54-7 T109 Organic Chemical T121 Pharmacologic Substance M0041050 M0307527 T337527 2,5-dimethoxy-4-ethylamphetamine, hydrochloride, (+-)-isomer 1999 08 18 M0307524 2,5-dimethoxy-4-ethylamphetamine, hydrochloride, (R)-isomer C0893928 42011-76-7 T109 Organic Chemical T121 Pharmacologic Substance M0041050 M0307524 T337524 2,5-dimethoxy-4-ethylamphetamine, hydrochloride, (R)-isomer 1999 08 18 M0307525 2,5-dimethoxy-4-ethylamphetamine, hydrochloride, (S)-isomer C0893929 50505-91-4 T109 Organic Chemical T121 Pharmacologic Substance M0041050 M0307525 T337525 2,5-dimethoxy-4-ethylamphetamine, hydrochloride, (S)-isomer 1999 08 18 C000988 1,2-dihydroxy-4-ketovaleric acid 1972 01 01 1982 09 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *VALERATES (72-76) GLYCOLS (72-82) KETO ACIDS (72-76) *D010421 Pentanoic Acids Biochemistry 11(12):2225;1972 NLM VSR NLM M0041013 1,2-dihydroxy-4-ketovaleric acid C0600947 Pentanoic acid, 2,3-dihydroxy-4-oxo- 37520-06-2 T071015 1,2-dihydroxy-4-ketovaleric acid C000992 S-(2,3-dihydroxyphenyl)cysteine 1972 01 01 1983 08 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CATECHOLS (72-82) *CYSTEINE (72-75) D003545 Cysteine *Q000031 analogs ; derivatives Biochim Biophys Acta 261(1):258;1972 NLM ACS NLM M0041016 S-(2,3-dihydroxyphenyl)cysteine C0600948 L-Cysteine, S-(2,3-dihydroxyphenyl)- 79329-88-7 T071018 S-(2,3-dihydroxyphenyl)cysteine C001001 diiodothreitol 1970 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 IODINE (70-76) *D013780 Tetroses NLM NLM M0041025 diiodothreitol C0600953 0 T071028 diiodothreitol C029242 pregnancy-associated murine protein 3 1981 05 04 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 glycoprotein with MW 65,000 ; isoelectric point of 4.1; present in male ; non-pregnant mice in small amounts, but in greatly elevated amount in pregnant mice 1 *D011257 Pregnancy Proteins Biol Reprod 1981;24(1):163 RLS WXM WXM M0093379 pregnancy-associated murine protein 3 C0612775 0 T123382 pregnancy-associated murine protein 3 T123381 PAMP-3 C013710 guaiacolsulfonic acid 1977 01 01 2001 07 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 elastomer used as dental impression material; mixture of the potassium salt of 4- ; 5-guaiacolsulfonic acid; RN given refers to parent cpd 3 D006139 Guaiacol *Q000031 analogs ; derivatives J Pharm Sci 68(1):118;1979 Rev Med Chir Soc Med Nat Iasi 82(1):131;1978 Rev Odontostomatol (Paris) 5(5):345;1976 NLM TWD TWD M0061685 guaiacolsulfonic acid C0061930 50855-43-1 1321-14-8 (mono-K salt) M0061685 M0061683 M0061685 M0312300 M0061685 M0061682 T091688 guaiacolsulfonic acid Merck Index, 9th ed, p. 7422 #7415 M0061683 guaiacolsulfonate potassium C0304572 M0061685 M0061683 T091686 guaiacolsulfonate potassium T091687 potassium guaiacolsulfonate M0312300 guaiacolsulfonic acid, monopotassium salt C0952652 1321-14-8 M0061685 M0312300 T342300 guaiacolsulfonic acid, monopotassium salt 1999 08 18 M0061682 Thiocol C0145631 M0061685 M0061682 T091685 Thiocol C001005 diisopropylphosphorylthiocholine iodide 1973 01 01 1998 05 20 1998 1999 2000 2001 2002 RN ; NM given refers to iodide 0 *ORGANOTHIOPHOSPHORUS COMPOUNDS (72-75) DIMETHYLAMINES (73-75) PHOSPHORYLCHOLINE/*analogs (75-82) D013860 Thiocholine *Q000031 analogs ; derivatives Molecular Pharmacol 7(2):129;1971 NLM BQV NLM M0041038 diisopropylphosphorylthiocholine iodide C0600958 O,O-diisopropyl S-(2-dimethylamino)ethylphosphorothiolate methiodide 2641-06-7 T071041 diisopropylphosphorylthiocholine iodide C001007 Dilavacol 1972 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 cpd drug contains guaiacol glyceryl ether ; camylofine 0 *GLYCINE (72-75) *D006140 Guaiacol Glyceryl Ether D004338 Drug Combinations D005998 Glycine *Q000031 analogs ; derivatives Therapie 26(3):431;1971 NLM VSR NLM M0041039 Dilavacol C0600959 Benzeneacetic acid, alpha-((2-(diethylamino)ethyl)amino)-, 3-methylbutyl ester, mixt. with 1-(4-hydroxy-3-methoxyphenyl)-1,2,3-propanetriol 76391-72-5 T071042 Dilavacol U.D. 18:115 I C009189 ritalinic acid 1974 01 01 2000 07 31 2001 2002 RN given refers to cpd without isomeric designation; structure 16 *METHYLPHENIDATE (74-75) D008774 Methylphenidate *Q000031 analogs ; derivatives Biomed Mass Spectrom 1979;6(10):422 Biomed Mass Spectrom 2(1):2;1975 Clin Chem 20(4):440;1974 Clin Chem 25(1):51;1979 Commun Psychopharmacol 2(3):203;1978 J Forensic Sci 24(1):55;1979 NLM WXM sjn M0053672 ritalinic acid C0073398 19395-41-6 T109 Organic Chemical T123 Biologically Active Substance 54631-24-2 ((R*,R*)-(+-)-isomer) M0053672 M0310629 T083675 ritalinic acid T083674 alpha-phenyl-2-piperidineacetic acid M0310629 ritalinic acid, (R*,R*)-(+-)-isomer C0895786 54631-24-2 T109 Organic Chemical T123 Biologically Active Substance M0053672 M0310629 T340629 ritalinic acid, (R*,R*)-(+-)-isomer 1999 08 18 C030270 IP25 1981 07 08 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 lysine-rich chromosomal protein found in mouse liver chromatin 2 *D002868 Chromosomal Proteins, Non-Histone Biochem Biophys Res Commun 1981;99(2):349 NBM WXM WXM M0095866 IP25 C0377376 0 T125870 IP25 T125869 IP25 chromosomal protein C030710 protein 315 1981 07 27 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 3 *D007070 Immunoglobulin A Biochemistry 1981;20(8):2339 MEG WXM WXM M0096941 protein 315 C0072337 0 T126945 protein 315 T126944 protein 315 (IgA-lambda 2) C001021 dimethylaminobornyl acetate methiodide 1974 01 01 1994 06 27 1995 1996 1997 1998 1999 2000 2001 2002 0 DIMETHYLAMINES (74-76) *D001892 Bornanes NLM MLH TPW M0041064 dimethylaminobornyl acetate methiodide C0600964 33124-27-5 T071067 dimethylaminobornyl acetate methiodide C009190 rodocaine 1974 01 01 2000 07 31 2001 2002 new long-acting local anesthetic; synonym R 22700 refers to HCl salt; RN given refers to (trans)-isomer; structure 0 PIPERIDINES (74-82) *D000813 Anilides Acta Anaesthesiol Belg 24(3):264;1973 NLM WXM sjn M0053675 rodocaine C0603878 38821-80-6 T109 Organic Chemical T121 Pharmacologic Substance 39489-95-7 ((trans)-(+-)-isomer) 39489-97-9 ((trans)-(+)-isomer) 39489-99-1 ((trans)-(-)-isomer) 39590-64-2 (mono-HCl(cis)-isomer) 41847-77-2 (HCl(trans)-isomer) M0053675 M0310631 M0053675 M0310630 M0053675 M0310632 M0053675 M0310634 M0053675 M0310633 M0053675 M0053673 T083678 rodocaine Negwer, 5th ed, #3718 USAN 1978, p.274 T083677 trans-6-chloro-2,3,4,4a,5,6,7,7a-octahydro-1H-cyclopenta(b)pyridine-1-propiono-o- toluidide M0310631 rodocaine, (trans)-(+)-isomer C0895788 39489-97-9 T109 Organic Chemical T121 Pharmacologic Substance M0053675 M0310631 T340631 rodocaine, (trans)-(+)-isomer 1999 08 18 M0310630 rodocaine, (trans)-(+-)-isomer C0895787 39489-95-7 T109 Organic Chemical T121 Pharmacologic Substance M0053675 M0310630 T340630 rodocaine, (trans)-(+-)-isomer 1999 08 18 M0310632 rodocaine, (trans)-(-)-isomer C0895789 39489-99-1 T109 Organic Chemical T121 Pharmacologic Substance M0053675 M0310632 T340632 rodocaine, (trans)-(-)-isomer 1999 08 18 M0310634 rodocaine, hydrochloride, (trans)-isomer C0895791 41847-77-2 T109 Organic Chemical T121 Pharmacologic Substance M0053675 M0310634 T340634 rodocaine, hydrochloride, (trans)-isomer 1999 08 18 M0310633 rodocaine, monohydrochloride, (cis)-isomer C0895790 39590-64-2 T109 Organic Chemical T121 Pharmacologic Substance M0053675 M0310633 T340633 rodocaine, monohydrochloride, (cis)-isomer 1999 08 18 M0053673 R 22700 C0603876 0 T109 Organic Chemical T121 Pharmacologic Substance M0053675 M0053673 T083676 R 22700 C001037 dimethylcarbamyl fluoride 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 DIMETHYLAMINES (73-76) *D002219 Carbamates Molec Pharmacol 7(2):129;1971 NLM NLM M0041103 dimethylcarbamyl fluoride C0600978 431-14-1 T071106 dimethylcarbamyl fluoride C001044 3,3-dimethylglycidic acid 1972 01 01 1982 10 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *BUTYRATES (72-82) *ETHERS, CYCLIC (72-75) *D004852 Epoxy Compounds Proc Nat Acad Sci USA 69(5):1173;1972 NLM VSR NLM M0041115 3,3-dimethylglycidic acid C0600980 0 T071118 3,3-dimethylglycidic acid C001046 1,8 beta-dimethyl-2-ketoperhydrindan-5 beta-methyl- 5 alpha-acetic acid 1970 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *INDENES (70-75) ACETIC ACIDS (70-76) *D007189 Indans NLM NLM M0041116 1,8 beta-dimethyl-2-ketoperhydrindan-5 beta-methyl- 5 alpha-acetic acid C0600981 0 T071119 1,8 beta-dimethyl-2-ketoperhydrindan-5 beta-methyl- 5 alpha-acetic acid C031044 cytoplasmic glycoprotein 1981 08 14 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 also a regulator of mitochondrial membrane permeability 7 *D006023 Glycoproteins D003593 Cytoplasm Dokl Akad Nauk SSSR 1981;257(5):1265 NBM WXM WXM M0097840 cytoplasmic glycoprotein C0056994 0 T127844 cytoplasmic glycoprotein T127843 insulin-dependent cytoplasmic regulator C001064 2,4-dimethylsulfolane 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 has effect on central nervous system; structure 0 CYCLIC S-OXIDES (72-76) *D013876 Thiophenes Acta Biol Med 26(5):1089;1971 Acta Biol Med Germ 37(8):1215;1978 NLM NLM M0041153 2,4-dimethylsulfolane C0045503 2,4-dimethyltetrahydrothiophene-1,1- dioxide 1003-78-7 T071156 2,4-dimethylsulfolane C001068 dimethylvinylsulfonium bromide 1973 01 01 1998 05 20 1998 1999 2000 2001 2002 0 *SULFIDES (73-82) ONIUM COMPOUNDS (74-76) *D014753 Vinyl Compounds Biochim Biophys Acta 269(3):322;1972 NLM BQV NLM M0041155 dimethylvinylsulfonium bromide C0600991 25709-51-7 T071158 dimethylvinylsulfonium bromide C001182 ethoprop 1973 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 7 *ORGANOTHIOPHOSPHORUS COMPOUNDS (73-82) PROPANE (73-75) PROPANE/analogs (75-82) *D013877 Thiophosphoric Acid Esters J Agric Food Chem 26(1):42;1978 NLM TWD TWD M0041289 ethoprop C0059728 O-ethyl S,S-dipropyl phosphorodithioate 13194-48-4 M0041289 M0041288 T071292 ethoprop M0041288 Mocap C0128799 M0041289 M0041288 T071291 Mocap C001071 2,4-dinitrobenzenesulfenamide 1972 01 01 1982 09 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 AMIDES (72-76) DINITROBENZENES (72-82) NITROBENZENES (72-77) *D013434 Sulfenic Acids J Pharm Sci 60(5):803;1971 NLM VSR NLM M0041158 2,4-dinitrobenzenesulfenamide C0600994 Benzenesulfenamide, 2,4-dinitro- 51824-83-0 T071161 2,4-dinitrobenzenesulfenamide C001072 2,4-dinitrophenylhydrazone 1972 01 01 1982 02 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 29 *NITROBENZENES (72-79) DINITROBENZENES (79-82) HYDRAZONES (72-74) *D006835 Hydrazones Anal Biochem 1979;96(1):94 Anal Biochem 90(1):359;1978 Biochem J 122(4):527;1971 Biochem J 1979;182(3):827 NLM NBM NLM M0041159 2,4-dinitrophenylhydrazone C0045521 0 T071162 2,4-dinitrophenylhydrazone C001077 dioxidine 1974 01 01 1998 08 19 1998 1999 2000 2001 2002 Russian drug; structure 124 CYCLIC N-OXIDES (74-76) *D011810 Quinoxalines D000336 Aerosols Farmakol Toksikol 35(2):229;1972 Farmakol Toksikol 41(2):199;1978 Genetika 14(5):900;1978 Khirurgiia 7:102;1976 Vestn Khir 119(9):48;1977 Vestn Khir 120(4):121;1978 NLM SXK NLM M0041165 dioxidine C0058339 2,3-bis(hydroxymethyl)quinoxaline-1,4-dioxide 17311-31-8 D000890 Anti-Infective Agents D009153 Mutagens M0041165 M0041164 T071168 dioxidine M0041164 2,3-quinoxalinedimethanol-1,4-dioxide C0282710 M0041165 M0041164 T071167 2,3-quinoxalinedimethanol-1,4-dioxide C001082 diphenylcresyl phosphate 1972 01 01 1983 07 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN given refers to cpd with unspecified locants 3 *ORGANOPHOSPHORUS COMPOUNDS *D003408 Cresols Z Gesamte Hyg 16(3):167;1970 NLM DLJ NLM M0041170 diphenylcresyl phosphate C0058378 26444-49-5 T071173 diphenylcresyl phosphate C001091 1,2-diphenyl-1-pyrrolidino ethane 1970 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 BENZYL COMPOUNDS (72-76) *D011759 Pyrrolidines NLM NLM M0041184 1,2-diphenyl-1-pyrrolidino ethane C0600998 0 T071187 1,2-diphenyl-1-pyrrolidino ethane C001226 fluenethyl 1972 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 FLUORINE (72-76) *D001713 Biphenyl Compounds J Agric Food Chem 20(1):62;1972 Survival Tox Environ WA670 S963:165;1973 NLM TWD TWD M0041330 fluenethyl C0060487 4-biphenylacetic acid 2-fluoroethyl ester 4301-50-2 T071333 fluenethyl T071332 2-fluoroethyl 4-biphenylacetate C001102 6,6'-dithiodinicotinic acid 1971 01 01 2001 01 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 18 DISULFIDES (72-76) *D009539 Nicotinic Acids D013439 Sulfhydryl Reagents BBA 467:364;1977 Biochem Biophys Res Commun 82(3):776;1978 Biochem J 173(2):701;1978 Biochem Pharmacol 24(1):49;1975 Biochimie 57(9):1087;1975 J Cell Physiol 85(3):547;1975 J Neurochem 25(3):359;1975 Z Lebensia Unters Forsch 167(4):256;1978 NLM CCR CCR M0041192 6,6'-dithiodinicotinic acid C0049414 6,6'-dithiobis-3-pyridinecarboxylic acid 15658-35-2 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid 35879-52-8 (Na salt) M0041192 M0307558 T071195 6,6'-dithiodinicotinic acid T071194 carboxypyridine disulfide M0307558 6,6'-dithiodinicotinic acid, sodium salt C0951025 35879-52-8 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0041192 M0307558 T337558 6,6'-dithiodinicotinic acid, sodium salt 1999 08 18 C037729 ATPase-binding protein (26,500) 1983 05 11 2001 01 25 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 subunit of H+-translocating ATPase; similar to but not identical to oligomycin sensitivity-conferring protein; MW 26,500 2 *D008565 Membrane Proteins D000251 Adenosinetriphosphatase D002352 Carrier Proteins J Biol Chem 1983;258(8):4788 RLS WXM WXM M0113959 ATPase-binding protein (26,500) C0052611 0 T143963 ATPase-binding protein (26,500) T143962 ATPase-BP 26 MW C001116 Dolibrax 1971 01 01 1986 08 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains chlordiazepoxide, propylphenazone, ; clidinium.HBr; spasmolytic ; analgesic 0 *ANTIPYRINE (74-75) *D002707 Chlordiazepoxide *D011812 Quinuclidines D000983 Antipyrine *Q000031 analogs ; derivatives D004338 Drug Combinations NLM PEH NLM M0041215 Dolibrax C0601013 1-Azoniabicyclo(2.2.2)octane, 3-((hydroxydiphenylacetyl)oxy)-1-methyl-, bromide, mixt. with 7-chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide and 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-pyrazol-3-one 76404-05-2 T071218 Dolibrax UD 22:54q C001118 Dolo-Adamon 1972 01 01 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination drug containing codeine, crotarbital, adamon ; dipyrone 0 *D000983 Antipyrine *D001463 Barbiturates *D002934 Cinnamates *D003061 Codeine D004338 Drug Combinations Z Allgemein Med 46(11):583;1971 NLM NLM M0041216 Dolo-Adamon C0058673 Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)-, phosphate (1:1) (salt), mixt. with 2-(1-bicyclo(2.2.1)hept-5-en-2-yl-1-phenylethoxy)-N,N-diethyl-N-methylethanaminium bromide, 5-(2-butenyl)-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione and sodium ((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino)methanesulfonate 76404-03-0 T071219 Dolo-Adamon UD 19:149a C001119 Dolo-Neurobion 1972 01 01 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains metamizol, vitamin B6, vitamin B1 ; vitamin B12 0 *D000983 Antipyrine *D014803 Vitamin B Complex D004338 Drug Combinations Z Allgemein Med 46(10):527;1970 NLM NLM M0041217 Dolo-Neurobion C0601014 Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride, mixt. with ((2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino)methanesulfonic acid sodium salt, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde and vitamin B12 76404-01-8 T071220 Dolo-Neurobion C001120 Dolo-Tensilan 1972 01 01 1980 10 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination consisting of propantheline bromide, perazine, codeine phosphate, ; aminophenazone 0 *MORPHINANS (72-75) *PHENOTHIAZINES (72-76) *D000983 Antipyrine *D010464 Perazine *D011413 Propantheline D003061 Codeine *Q000031 analogs ; derivatives D004338 Drug Combinations NLM RLS NLM M0041218 Dolo-Tensilan C0601015 0 T071221 Dolo-Tensilan C038157 apolipoprotein E isoproteins 1983 06 22 2001 01 25 1999 2000 2001 2001A 2002 increased in VLDL of diabetic patients; see also records for apo E1, apo E2, apoE3, apo E4, apo E5 ; apoE7 20 *APOLIPOPROTEINS (83-84) *D001057 Apolipoproteins E D008079 Lipoproteins, VLDL Horm Metab Res 1983;15(4):201 RLS WXM WXM M0114996 apolipoprotein E isoproteins C0052194 0 T145000 apolipoprotein E isoproteins T144999 apo E isoproteins C001123 dopachrome 1972 01 01 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 cyclization product of L-DOPA 66 *DOPA (72-72) *D007211 Indoles *D011809 Quinones Biochem Pharm 25(5):533;1976 NLM NLM M0041223 dopachrome C0058688 3571-34-4 T071226 dopachrome C078790 GR 117289 1993 01 21 2001 01 11 1996 1997 1998 1999 2000 2001 2001A 2002 angiotensin AT1 receptor antagonist; structure given in first source 15 *D009539 Nicotinic Acids *D013777 Tetrazoles D011945 Receptors, Angiotensin Q000037 antagonists ; inhibitors Br J Pharmacol 1992 Dec;107(4):1173-80 THA CCR CCR M0211099 GR 117289 C0211676 145781-32-4 T109 Organic Chemical T121 Pharmacologic Substance M0211099 M0211092 M0211099 M0211093 M0211099 M0211094 T241104 GR 117289 T241102 GR117289 T241100 GR-117289 M0211092 1-((3-bromo-2-(2-(1H-tetrazol-5-yl)phenyl)-5-benzofuranyl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid C0211675 T109 Organic Chemical T121 Pharmacologic Substance M0211099 M0211092 T241097 1-((3-bromo-2-(2-(1H-tetrazol-5-yl)phenyl)-5-benzofuranyl)methyl)-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid M0211093 3-(3-bromo-2-(2-(1H-tetrazol-5-yl)phenyl)benzofuran-5-ylmethyl)-2-butyl-5-chloro-3H-imidazole-4-carboxylic acid C0287923 T109 Organic Chemical T121 Pharmacologic Substance M0211099 M0211093 T241098 3-(3-bromo-2-(2-(1H-tetrazol-5-yl)phenyl)benzofuran-5-ylmethyl)-2-butyl-5-chloro-3H-imidazole-4-carboxylic acid M0211094 GR 117289X C0287926 T109 Organic Chemical T121 Pharmacologic Substance M0211099 M0211094 T241099 GR 117289X T241101 GR-117289X T241103 GR117289X C001126 Drixoral 1972 01 01 1994 06 23 1995 1996 1997 1998 1999 2000 2001 2002 combination drug: isoephedrine; dexbrompheniramine 1 *PYRIDINES (72-75) *D001977 Brompheniramine *D004809 Ephedrine D004338 Drug Combinations Eye Ear Nose Throat 51(1):9;1972 NLM MLH TPW M0041225 Drixoral C0058751 Benzenemethanol, alpha-(1-(methylamino)ethyl)-, (S-(R*,R*))-, sulfate (2:1) (salt), mixt. with (S)-gamma-(4-bromophenyl)-N,N-dimethyl-2-pyridinepropanamine (Z)-2-butenedioate (1:1) 76404-09-6 T071228 Drixoral C001168 ethisolide 1972 01 01 2002 04 26 1994 1995 1996 1997 1998 1999 2000 2001 2002 2002A mold metabolites; structure 2 *BICYCLO CPDS (75-82) *BRIDGED CPDS (72-75) *D005663 Furans J Chem Soc 13:2431;1971 NLM CCR CCR M0041262 ethisolide C0601026 4-ethyl-3a,6a-dihydro-3-methylenefuro(3,4-b)furan- 2(3H),6(4H)-dione 33644-10-9 T109 Organic Chemical T195 Antibiotic M0041262 M0041260 T071265 ethisolide T071264 4-ethyl-3a,6a-dihydro-3-methylenefuro(3,4-b)furan-2,6(3H,4H)-dione M0041260 4-epi-ethisolide C0601024 T109 Organic Chemical T195 Antibiotic M0041262 M0041260 T071263 4-epi-ethisolide C001141 elsholtzidiol 1970 01 01 1982 09 21 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 BUTANEDIOLS (75-82) GLYCOLS (70-75) *D005663 Furans NLM VSR NLM M0041231 elsholtzidiol C0601019 28666-20-8 T071234 elsholtzidiol C452871 caledonixanthone F 2002 04 28 2002 04 28 2002 2002A Isolated from Calophyllum caledonicum; structure in first source 1 *D014966 Xanthenes Planta Med 2002 Jan;68(1):41-4 SZM SZM SZM M0421883 caledonixanthone F 0 T109 Organic Chemical T121 Pharmacologic Substance T491360 caledonixanthone F 2002 04 28 C081174 A 81988 1993 06 10 2001 01 11 1995 1996 1997 1998 1999 2000 2001 2001A 2002 angiotensin II antagonist selective for type 1 receptors 13 *D009539 Nicotinic Acids *D013777 Tetrazoles Hypertension 1993 May;21(5):660-6 PML CCR CCR M0216587 A 81988 C0216139 141887-34-5 T109 Organic Chemical T121 Pharmacologic Substance M0216587 M0216583 T246592 A 81988 T246589 A-81988 T246590 A81988 T246591 Abbott-81988 M0216583 2-(N-propyl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)amino)pyridine-3-carboxylic acid C0216138 T109 Organic Chemical T121 Pharmacologic Substance M0216587 M0216583 T246588 2-(N-propyl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)amino)pyridine-3-carboxylic acid C001161 estrocyanate 1972 01 01 1991 06 03 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ESTROGENS (72-75) CYANATES (72-75) NITRILES (72-82) *D004962 Estranes D004969 Estrogens, Synthetic Dtsch Gesundheitsw 26(34):1614;1971 NLM LBG NLM M0041250 estrocyanate C0601023 0 T071253 estrocyanate C001164 etazocine 1971 01 01 1984 08 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *AZOCINES (71-81) ALCOHOLS (71-76) *D001575 Benzomorphans NLM GTC NLM M0041255 etazocine C0162897 1,2,3,4,5,6-hexahydro-6,11-diethyl- 3-methyl-2,6-methano-3-benzazocin-8-ol 34254-87-0 T071258 etazocine C452872 caledonixanthone E 2002 04 28 2002 Isolated from Calophyllum caledonicum; structure in first source 1 *D014966 Xanthenes Planta Med 2002 Jan;68(1):41-4 SZM SZM M0421884 caledonixanthone E 0 T109 Organic Chemical T121 Pharmacologic Substance T491361 caledonixanthone E 2002 04 28 C452873 3,5-dihydroxy-4-methoxyxanthone 2002 04 28 2002 structure in first source 1 *D014966 Xanthenes Planta Med 2002 Jan;68(1):49-54 SZM SZM M0421886 3,5-dihydroxy-4-methoxyxanthone 0 T109 Organic Chemical T121 Pharmacologic Substance T491363 3,5-dihydroxy-4-methoxyxanthone 2002 04 28 T491364 3,5-DMX 2002 04 28 C001171 ethoxychlor 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *HYDROCARBONS, HALOGENATED (73-75) *INSECTICIDES, ORGANOCHLORINE (73-75) ETHYL ETHERS (73-76) D008731 Methoxychlor *Q000031 analogs ; derivatives J Agric Food Chem 20(1):1;1972 NLM NLM M0041263 ethoxychlor C0601027 2,2-bis(p-ethoxyphenyl)-1,1,1-trichloroethane 4329-03-7 T071266 ethoxychlor C001172 9-ethyladenine 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 13 *ADENINE (72-75) D000225 Adenine *Q000031 analogs ; derivatives Biochemistry 11(5):816;1972 Photochem Photobiol 22(3-4):97;1975 NLM NLM M0041264 9-ethyladenine C0050225 2715-68-6 T071267 9-ethyladenine C001174 2-ethyl-4-amino-6-methoxy-s-triazine 1971 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 AMINES (72-76) *D014227 Triazines NLM NLM M0041270 2-ethyl-4-amino-6-methoxy-s-triazine C0601028 1,3,5-Triazin-2-amine, 4-ethyl-6-methoxy- 701-78-0 T071273 2-ethyl-4-amino-6-methoxy-s-triazine C452874 6-methyl-2,4-dihydroxyphenyl 4-O-methyl-glucopyranoside 2002 04 28 2002 structure in first source 1 *D009005 Monosaccharides Planta Med 2002 Jan;68(1):64-5 SZM SZM M0421887 6-methyl-2,4-dihydroxyphenyl 4-O-methyl-glucopyranoside 0 T109 Organic Chemical T118 Carbohydrate T491365 6-methyl-2,4-dihydroxyphenyl 4-O-methyl-glucopyranoside 2002 04 28 T491366 6-MDP-MGlu 2002 04 28 C452875 terredionol 2002 04 28 2002 structure in first source 0 *D003512 Cyclohexanones Planta Med 2002 Jan;68(1):64-5 SZM SZM M0421888 terredionol 0 T109 Organic Chemical T491367 terredionol 2002 04 28 C452876 methyl psilalate 2002 04 28 2002 structure in first source 1 *D000447 Aldehydes *D000475 Alkenes Planta Med 2002 Jan;68(1):66-7 SZM SZM M0421889 methyl psilalate 0 T121 Pharmacologic Substance T195 Antibiotic T491368 methyl psilalate 2002 04 28 C001183 ethylene di-11-bromoundecanoate 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 BROMINE (72-76) ETHYLENES (72-76) *D005227 Fatty Acids Science 176(036):806;1972 NLM NLM M0041290 ethylene di-11-bromoundecanoate C0601032 39630-55-2 T071293 ethylene di-11-bromoundecanoate C001186 ethylethyleneimine 1970 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *AZIRINES (70-74) *D001388 Aziridines NLM NLM M0041291 ethylethyleneimine C0059824 Aziridine, 1-ethyl- 1072-45-3 T071294 ethylethyleneimine C001189 N'-ethyl-2-methyl-N(3)-(2,6-dimethylphenyl)-4- imidazolidinone 1971 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 a metabolite of lidocaine 0 XYLENES (72-76) *D007093 Imidazoles NLM NLM M0041294 N'-ethyl-2-methyl-N(3)-(2,6-dimethylphenyl)-4- imidazolidinone C0067104 32845-42-4 T071297 N'-ethyl-2-methyl-N(3)-(2,6-dimethylphenyl)-4- imidazolidinone C001195 4-ethylsulfonylnaphthalene-1-sulfonamide 1972 01 01 1982 03 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 3 SULFONAMIDES SULFONES (72-76) *D009281 Naphthalenes Ann Clin Lab Sci 6(3):223;1976 Biochem Med 12(4):313;1975 Br J Cancer 23:772;1969 Br J Cancer 31(5):585;1975 Chem Biol Interact 1(1):49;1969 Clin Toxicol W3 EX89 (417):177;1976 J Natl Cancer Inst 46:337;1971 J Natl Cancer Inst 51:2007;1973 NLM MGR NLM M0041297 4-ethylsulfonylnaphthalene-1-sulfonamide C0048265 842-00-2 T071300 4-ethylsulfonylnaphthalene-1-sulfonamide C001200 eupatolide 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 sesquiterpene lactone from Eupatorium formasanum HAY; structure 0 *ANTINEOPLASTIC AGENTS (72-75) *TERPENES (72-74) LACTONES (74-76) *D012717 Sesquiterpenes J Pharm Sci 61(4):629;1972 NLM NLM M0041300 eupatolide C0601036 6750-25-0 T071303 eupatolide C001201 Eupond 1972 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains inulin: choline ; intybin 0 *D002794 Choline *D003508 Cycloheptanes *D007444 Inulin D004338 Drug Combinations D009765 Obesity Q000188 drug therapy Med Monatschr 25(12):554;1971 NLM VSR NLM M0041301 Eupond C0601037 77430-01-4 T071304 Eupond C001222 flavaspidic acid-N-methylglucaminate 1971 01 01 1982 02 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 AMINO SUGARS (71-76) GLUCOSE (71-74) MEGLUMINE/analogs (76-82) *D002090 Butyrophenones Br J Pharm 27(20):2425;1978 Life Sci 24(7):587;1979 NLM NBM NLM M0041328 flavaspidic acid-N-methylglucaminate C0060428 992-18-7 T071331 flavaspidic acid-N-methylglucaminate C001252 nefurthiazole 1970 01 01 2001 01 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 7 *THIAZOLES (70-82) HYDRAZINES (70-79) *D009581 Nitrofurans Cancer Res 33(11):2802;1973 Cancer Res 38:1398;1978 NLM CCR CCR M0041365 nefurthiazole C0068487 formic acid 2-(4-(5-nitro-2-furyl)-2- thiazolyl)hydrazide 3570-75-0 T109 Organic Chemical T131 Hazardous or Poisonous Substance T071368 nefurthiazole T071367 2-FNT T071366 2-(4-(5-nitro-2-furyl)-2-thiazolyl)formic acid hydrazide C001235 6-fluoro-N,N-diethyltryptamine 1970 01 01 1983 08 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN not in Chemline 8/11/83; structure 0 FLUORINE (70-76) *D014363 Tryptamines NLM JSL NLM M0041343 6-fluoro-N,N-diethyltryptamine C0601040 2560-29-4 T071346 6-fluoro-N,N-diethyltryptamine C001335 hexachlorobutadiene 1971 01 01 2001 02 12 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a potent nephrotoxicant in rats; structure 124 CHLORINE (71-74) *D002070 Butadienes Am Ind Hyg Assn J 38(11):589;1977 Arch Toxicol 1979;43(1):47 Environ Health Perspect 21:49;1977 Gig Sanit 6:66;1977 IARC Monogr Eval Carcinog Risk Chem Hum 1979;20:179 J Assn Off Anal Chem 59(3):552;1976 Sublethol Effect of Toxic Chem on Aquatic Animals WA 689 5941 1975 p.167 Toxicol Appl Pharm 47(1):1;1979 Toxicology 1979;14(1):55 NLM CCR CCR M0041474 hexachlorobutadiene C0062602 87-68-3 D005659 Fungicides, Industrial T071477 hexachlorobutadiene T071475 hexachloro-1,3-butadiene T071476 hexachlorobuta-1,3-diene C014705 nitroethane 1977 01 01 2001 01 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 20 *D009595 Nitroparaffins D004980 Ethane *Q000031 analogs ; derivatives J Biol Chem 252(12):4361;1977 NLM CCR CCR M0063442 nitroethane C0068831 79-24-3 T109 Organic Chemical T093445 nitroethane C001249 5-formamido-1-beta-D-ribofuranosylthioimidazole-4-carboxamide 2',3',5'-triformate 1972 01 01 1983 08 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *NUCLEOSIDES (72-73) IMIDAZOLES (72-82) THIONES (74-76) *D012263 Ribonucleosides Cancer Chemother Rep 55(3):229;1971 NLM JSL NLM M0041361 5-formamido-1-beta-D-ribofuranosylthioimidazole-4-carboxamide 2',3',5'-triformate C0601044 27115-65-7 T071364 5-formamido-1-beta-D-ribofuranosylthioimidazole-4-carboxamide 2',3',5'-triformate C018247 chinoin 123 1979 01 01 2001 01 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2001B 2001C 2002 4 PYRIDINES (79-82) *D011743 Pyrimidines Acta Morphol Acad Sci Hung 1979;27(1-2):38 Acta Pharm Hung 48(Suppl):40;1978 Internat Symp State Prev Ther Hum Arterosclerosis Anim Models: WG 550 I6222i:187;1977 Pharmazie 1979;34(9):551 Ther Hung 26(4):171;1978 Ther Hung 26(4):174;1978 Ther Hung 26(4):178;1978 NLM TWD TWD M0069583 chinoin 123 C0055308 3-(ethoxycarbonyl)-6,7,8,9-tetrahydro-6-methyl-4-oxo-4H-pyrido(1,2-a)pyrimidine-9-acetic acid 64405-40-9 T109 Organic Chemical T121 Pharmacologic Substance M0069583 M0069581 T099586 chinoin 123 T099583 3-carbethoxy-6-methyl-9-carboxymethyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido(1,2-A)pyrimidine M0069581 CH 123 C0109241 T109 Organic Chemical T121 Pharmacologic Substance M0069583 M0069581 T099584 CH 123 T099585 CH-123 C035314 1-nitropropane 1982 08 20 2001 01 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 12 *D009595 Nitroparaffins D011407 Propane *Q000031 analogs ; derivatives Ecotoxicol Environ Safety 1982;6(3):268 CHA CCR CCR M0108320 1-nitropropane C0044507 108-03-2 T109 Organic Chemical T138324 1-nitropropane C095244 antibacterial protein, Entamoeba 1995 09 22 2001 02 13 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a major antibacterial protein of the protozoan parasite, Entamoeba histolytica with lysozyme-like properties; MW 23 kDa; amino acid sequence given in first source; GenBank X87610 2 *D015800 Protozoan Proteins D009113 Muramidase Eur J Biochem 1995 Aug 1;231(1):831-8 BMB WXM WXM M0250850 antibacterial protein, Entamoeba C0380680 0 T280855 antibacterial protein, Entamoeba T280854 Entamoeba bacteriolytic protein C001256 Fortalidon 1972 01 01 1983 08 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 Contains aminopyrin, aspirin, codeine and barbiturate 0 *D000632 Aminopyrine *D001241 Aspirin *D001463 Barbiturates *D003061 Codeine D004338 Drug Combinations Med Welt 23(13):468;1972 NLM JSL NLM M0041368 Fortalidon C0601047 67797-89-1 T071371 Fortalidon C001257 Fostex 1971 01 01 1990 07 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 for acne drug therapy; contains 2% sulfur sebolytic; 2% salicylic acid; 1% hexachlorophene 0 *RESORCINOLS (71-75) *D006582 Hexachlorophene *D012461 Salicylic Acids *D013455 Sulfur D004338 Drug Combinations NLM SXR NLM M0041369 Fostex C0601048 Benzoic acid, 2-hydroxy-, mixt. with 2,2'-methylenebis(3,4,6-trichlorophenol) and sulfur 77536-63-1 T071372 Fostex UD 8:42h C001258 franol 1971 01 01 1997 08 13 1998 1999 2000 2001 2002 contains luminal, theophylline, ephderine, thenfadil 1 *D004809 Ephedrine *D005029 Ethylenediamines *D010634 Phenobarbital *D013806 Theophylline D004338 Drug Combinations D001249 Asthma Q000188 drug therapy NLM MLH BVL M0041370 franol C0060746 8058-86-4 T071373 franol UD 13: ?K UD 14:86d C095247 24-kDa protein, Haemophilus 1995 09 22 2001 02 13 1996 1997 1998 1999 2000 2001 2001A 2002 from Haemophilus ducreyi; N-terminal amino acid sequence given in first source 2 *D001425 Bacterial Outer Membrane Proteins D000942 Antigens, Bacterial J Med Microbiol 1995 Sep;43(3):192-200 BMB WXM WXM M0250856 24-kDa protein, Haemophilus C0380686 0 T280861 24-kDa protein, Haemophilus T280860 Haemophilus 24-kDa surface protein C001261 fucothricin 1972 01 01 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 AMINOGLYCOSIDES (72-87) ANTIBIOTICS (72-87) GLYCOSIDES (72-74) *D000901 Antibiotics, Aminoglycoside Hindustan Antibot Bull 14(1):4;1971 NLM NLM M0041376 fucothricin C0601049 12676-47-0 T071379 fucothricin C020375 isaxonine 1979 01 01 2001 01 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 promotes nerve growth 51 *D011743 Pyrimidines Br J Clin Pharmacol 1980;9(3):275 Experientia 35(5):626;1979 NLM TWD TWD M0074028 isaxonine C0063890 2-Pyrimidinamine, N-(1-methylethyl)- 4214-72-6 T109 Organic Chemical T121 Pharmacologic Substance M0074028 M0074026 M0074028 M0074025 M0074028 M0074027 T104031 isaxonine M0074026 isopropylamino-2-pyrimidine phosphate C0124182 T109 Organic Chemical T121 Pharmacologic Substance M0074028 M0074026 T104029 isopropylamino-2-pyrimidine phosphate M0074025 N-isopropyl-amino-2-pyrimidine orthophosphate C0131202 T109 Organic Chemical T121 Pharmacologic Substance M0074028 M0074025 T104028 N-isopropyl-amino-2-pyrimidine orthophosphate M0074027 Nerfactor C0132167 T109 Organic Chemical T121 Pharmacologic Substance M0074028 M0074027 T104030 Nerfactor C001269 galactocarolose 1972 01 01 1989 09 20 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 galactofuranose polymer 0 *POLYSACCHARIDES (72-79) GALACTOSE (72-75) GALACTOSE/analogs (75-79) *D005685 Galactans Biochem J 122(1):49;1971 NLM RJM RLS M0041383 galactocarolose C0601051 0 T071386 galactocarolose C001273 galactosyl-beta-D-(1-4)-N-acetyllactosamine 1972 01 01 1995 06 20 1995 1996 1997 1998 1999 2000 2001 2002 0 *OLIGOSACCHARIDES (72-75) *D014312 Trisaccharides J Biol Chem 247(12):3744;1972 NLM MLH NLM M0041384 galactosyl-beta-D-(1-4)-N-acetyllactosamine C0601052 D-Glucitol, O-beta-D-galactopyranosyl-(1-4)-O-beta-D-galactopyranosyl-(1-4)-2-(acetylamino)-2-deoxy- 77416-66-1 T071387 galactosyl-beta-D-(1-4)-N-acetyllactosamine C001274 Gapona 1972 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains Gastrixon ; Halidor 0 *CYCLOHEPTANES (72-75) *PROPYLAMINES (72-75) *D001537 Bencyclane *D014326 Tropanes D004338 Drug Combinations Therap Hungarica 19(4):156;1971 NLM VSR NLM M0041385 Gapona C0601053 8-Azoniabicyclo(3.2.1)octane, 8,8-dimethyl-3-((9H-xanthen-9-ylcarbonyl)oxy)-, bromide, endo-, mixt. with N,N-dimethyl-3-((1-(phenylmethyl)cycloheptyl)oxy)-1-propanamine 77416-70-7 T071388 Gapona C001275 gaylussacin 1972 01 01 1986 05 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *GLYCOSIDES (72-75) *D005960 Glucosides *D013267 Stilbenes J Nat Prod 35(1):49;1972 NLM MEG NLM M0041386 gaylussacin C0601054 5-(beta-D-glucosyloxy)-3-hydroxy-trans- stilbene-2-carboxylic acid 38232-08-5 T071389 gaylussacin C002887 bis(4-nitrophenyl)phosphate 1973 01 01 2001 01 12 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd 65 *ORGANOPHOSPHORUS COMPOUNDS (73-81) *D009596 Nitrophenols D002265 Carboxylic Ester Hydrolases Q000037 antagonists ; inhibitors Adv Exp Med Biol 114:486;1979 Anesthesiology 50(3):228;1979 Anesthiol 45(6):629;1976 Biochem Pharm 25(12):1351;1976 Biochem Pharm 27(20):2431;1978 Biochem Pharmacol 1979;28(17):2685 Biochem Pharmacol 27(18):2269;1978 Biochem Pharmacol 27:733;1978 Biochim Biophys Acta 525(1):74;1978 Biochim Biophys Acta 572(3):519;1979 Eur J Biochem 1979;102(2):509 J Biochem 73(1):23;1973 Porphyrins Human Dis W3 IN862:10;1976 NLM CCR CCR M0043693 bis(4-nitrophenyl)phosphate C0053708 645-15-8 T109 Organic Chemical D004791 Enzyme Inhibitors 10331-55-2 (Ca salt) 4043-96-3 (Na salt) M0043693 M0308104 M0043693 M0308105 T073696 bis(4-nitrophenyl)phosphate T073694 bis(p-nitrophenyl)phosphate T073695 bis-p-nitrophenyl phosphate T073693 BNPP-4 M0308104 bis(4-nitrophenyl)phosphate, calcium salt C0951149 10331-55-2 T109 Organic Chemical M0043693 M0308104 T338104 bis(4-nitrophenyl)phosphate, calcium salt 1999 08 18 M0308105 bis(4-nitrophenyl)phosphate, sodium salt C0951150 4043-96-3 T109 Organic Chemical M0043693 M0308105 T338105 bis(4-nitrophenyl)phosphate, sodium salt 1999 08 18 C095256 colicin 10 1995 09 22 2001 02 13 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence in first source 4 *D003087 Colicins Mol Microbiol 1995 Apr;16(1):57-67 THA WXM WXM M0250879 colicin 10 C0380708 0 T280884 colicin 10 T280883 Col10 protein C001294 glucosoxime 1970 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 GLUCOSE (70-75) GLUCOSE/analogs (75-82) *D010091 Oximes NLM VSR NLM M0041399 glucosoxime C0061425 608-81-1 T071402 glucosoxime C095258 HXT7 protein 1995 09 22 2001 02 13 1995 1996 1997 1998 1999 2000 2001 2001A 2002 isolated from Saccharomyces cerevisiae; amino acid sequence in first source; GenBank Z31693 10 *D005656 Fungal Proteins *D009004 Monosaccharide Transport Proteins Mol Microbiol 1995 Apr;16(1):157-67 THA WXM WXM M0250883 HXT7 protein C0380712 0 T280888 HXT7 protein T280887 HXT7 gene product C001304 glyceryl sulfoquinovoside 1972 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *GLYCOSIDES (72-75) GLYCERIN (72-75) GLYCERIN/analogs (75-82) METHANESULFONATES (74-76) *D006017 Glycolipids Biochim Biophys Acta 261(1):35;1972 NLM VSR NLM M0041423 glyceryl sulfoquinovoside C0601058 2,3-dihydroxypropyl 6-deoxy-6-sulfo-alpha-D- glucopyranoside 2308-53-4 T071426 glyceryl sulfoquinovoside C001305 glycidol phosphate 1972 01 01 1982 07 23 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ETHERS, CYCLIC (72-75) ALCOHOL, PROPYL (72-76) ORGANOPHOSPHORUS COMPOUNDS (72-82) *D004852 Epoxy Compounds J Biol Chem 246(17):5510;1971 NLM CHA NLM M0041424 glycidol phosphate C0061588 23815-70-5 T071427 glycidol phosphate C001327 hayatinin methochloride 1970 01 01 1992 06 22 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D000470 Alkaloids NLM MLH TPW M0041459 hayatinin methochloride C0601061 29900-15-0 T071462 hayatinin methochloride C001328 hedamycin 1972 01 01 1997 03 31 1997 1998 1999 2000 2001 2002 17 ANTHRAQUINONES (72-95) *D000880 Anthraquinones Annu Rev Biochem 40:775;1971 Biochemistry 17(20):4232;1978 Helv Chim Acta 60(3):896;1977 NLM TBT NLM M0041460 hedamycin C0062164 11048-97-8 T071463 hedamycin C001329 helenalin 1972 01 01 1997 12 03 1998 1999 2000 2001 2002 toxic principle of Helenium microcephalum (smallhead sneezeweed); structure 40 *ANTINEOPLASTIC AGENTS (72-77) *TERPENES (72-74) LACTONES (72-77) *D012717 Sesquiterpenes D014118 Toxins Am J Vet Res 37(7):859;1976 J Med Chem 15(6):609;1972 J Med Chem 20(3):333;1977 J Med Chem 21(7):698;1978 J Med Chem 21(8):819;1978 J Pharm Sci 66(8):1194;1977 J Pharm Sci 67(4):552;1978 Science 196(4289):533;1977 NLM BMB NLM M0041461 helenalin C0062169 6754-13-8 D000894 Anti-Inflammatory Agents, Non-Steroidal D000972 Antineoplastic Agents, Phytogenic D002316 Cardiotonic Agents D010975 Platelet Aggregation Inhibitors T071464 helenalin Merck Index, 9th ed, p. 603, #4481 C001330 hellebrigenin 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 *D002018 Bufanolides Molec Pharmacol 8(1):31;1972 NLM NLM M0041462 hellebrigenin C0062191 465-90-7 T071465 hellebrigenin C001332 hemichrome 1972 01 01 1983 06 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 heme protein 51 *HEME (72-73) *PROTEINS (72-73) *D006420 Hemeproteins Blood 39(6):794;1972 NLM JSL NLM M0041463 hemichrome C0062223 haemichrome 0 T071466 hemichrome C001340 hexahydrospinamycin 1972 01 01 1983 08 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 SUCCINATES (72-83) *D010659 Phenylhydrazines J Med Chem 15(3):339;1972 NLM ACS NLM M0041483 hexahydrospinamycin C0601066 21471-49-8 T071486 hexahydrospinamycin C001341 hexahydroubiquinone-4 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 4 *UBIQUINONE (72-75) D014451 Ubiquinone *Q000031 analogs ; derivatives Int. Z. Vitaminforsch. 41(2):189;1971 Kardiologiia 17(12):79;1977 NLM NLM M0041484 hexahydroubiquinone-4 C0062633 phytylubiquinone /OD/ hexahydrocoenzyme Q4 362-45-8 T071487 hexahydroubiquinone-4 C001442 N,N'-(iminoditrimethylene)di-p-toluenesulfonamide 1972 01 01 2001 02 02 1998 1999 2000 2001 2001A 2002 therapeutic agent for myocardial necrosis; RN given refers to HCl 0 IMINES (72-82) TOLUENE (72-73) *D013449 Sulfonamides D014050 Toluene *Q000031 analogs ; derivatives Ann NY Acad Sci 156(1):294;1969 NLM TWD TWD M0041646 N,N'-(iminoditrimethylene)di-p-toluenesulfonamide C0601095 N,N'-(iminodi-3,1-propanediyl)bis(4- methylbenzenesulfonamide) 13380-01-3 M0041646 M0041647 T071649 N,N'-(iminoditrimethylene)di-p-toluenesulfonamide M0041647 Ro 5-5340 C0601096 M0041646 M0041647 T071650 Ro 5-5340 C001358 hycanthone methanesulfonate 1972 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 5 *THIOXANTHENES (74-75) *XANTHENES (72-74) ALKYL SULFONATES (73-74) METHANESULFONATES (74-82) D006826 Hycanthone *Q000031 analogs ; derivatives East African Med J 48(6):247;1971 NLM RLS NLM M0041507 hycanthone methanesulfonate C0063050 30922-68-0 T071510 hycanthone methanesulfonate C051845 alpha-fetoprotein gene-binding nuclear protein 1987 04 20 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 MW 149,000; from alpha-fetoprotein producing rat hepatomas 1 *D004268 DNA-Binding Proteins *D009363 Neoplasm Proteins D009687 Nuclear Proteins Biochem Biophys Res Commun 1987;143(1):110 MEG WXM WXM M0147413 alpha-fetoprotein gene-binding nuclear protein C0630141 0 T177418 alpha-fetoprotein gene-binding nuclear protein T177417 AFP G BP C001381 hydroxycotinine 1972 01 01 2000 12 07 1998 1999 2000 2001 2001A 2002 metabolite of nicotine; RN given refers to (S)-isomer; structure 44 *PYRROLIDINONES (72-75) PYRIDINES (72-75) D003367 Cotinine *Q000031 analogs ; derivatives J Med Chem 15(4):356;1972 NLM CCR CCR M0041542 hydroxycotinine C0063125 3-hydroxy-1-methyl-5-(3-pyridinyl)-2- pyrrolidinone 27323-64-4 T109 Organic Chemical T071545 hydroxycotinine T071544 3'-hydroxycotinine T071543 1-methyl-3-hydroxy-5-(3-pyridyl)-2-pyrrolidinone C001769 veronamine 1972 01 01 2001 01 25 1998 1999 2000 2001 2001A 2002 has cardiovascular effects; RN given refers to (R)-isomer 0 *ALKALOIDS (72-76) BENZYL CPDS (72-75) GLYCOSIDES (76-82) *D007546 Isoquinolines Arch Int Pharmacodyn Ther 198(2):392;1972 NLM TWD TWD M0042092 veronamine C0601189 (R-)- trimethoxy-1,2,3,4-tetrahydro-5,6,7-trimethoxy-2-methyl-1- 4-((1,2,3,4-tetrahydro-5,6,7-trimethoxy-2-methyl-1-isoquinolinyl)methyl)phenyl 6-deoxy-alpha-L-manno pyranoside 36388-20-2 T072095 veronamine T072094 1-(4'-alpha-L-rhamnosidobenzyl)-2-methyl-5,6,7- trimethoxy-1,2,3,4-tetrahydroisoquinoline C051924 bsg25D protein, Drosophila 1987 04 30 2001 01 25 1997 1998 1999 2000 2001 2001A 2002 blastoderm-specific locus encoding predicted protein; amino acid sequence given in first source 1 *PROTEINS (87-96) *D019476 Insect Proteins Nucleic Acids Res 1987;15(5):2309 MEG WXM WXM M0147615 bsg25D protein, Drosophila C0630210 108728-27-4 T177620 bsg25D protein, Drosophila T177619 protein bsg-25-D C001772 amicarbalide diisethionate 1972 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 12 *AMIDINES (72-81) *D002224 Carbanilides Arch Int Pharmacodyn Ther 198(2):248;1972 J Protozool 1979;26(4):657 NLM TWD TWD M0042099 amicarbalide diisethionate C0051576 3,3'-diamidino carbanilide diisethionate 3671-72-5 M0042099 M0042098 T072102 amicarbalide diisethionate M0042098 Diampron C0113568 M0042099 M0042098 T072101 Diampron C001899 triptolide 1973 01 01 2002 02 05 1996 1997 1998 1999 2000 2001 2001A 2001B 2001C 2001D 2002 2002A from Chinese herb, Tripterygium wilfordii; structure 46 *PHENANTHRENES (73-79) EPOXY CPDS (75-76) ETHERS, CYCLIC (73-75) LACTONES (73-79) *D004224 Diterpenes J Am Chem Soc 94(20):7194;1972 J Org Chem 42(15):2569;1977 NLM CCR CCR M0042303 triptolide C0077274 38748-32-2 T109 Organic Chemical T121 Pharmacologic Substance D000894 Anti-Inflammatory Agents, Non-Steroidal D000988 Antispermatogenic Agents D007166 Immunosuppressive Agents D018906 Antineoplastic Agents, Alkylating M0042303 M0377212 T072306 triptolide M0377212 PG490 C0971326 T109 Organic Chemical T121 Pharmacologic Substance M0042303 M0377212 T432312 PG490 2001 01 04 C001365 N-hydroxy-4-acetylaminobiphenyl 1971 01 01 2000 09 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 structure 16 *BIPHENYL CPDS (71-75) HYDROXAMIC ACIDS (75-82) *D000611 Aminobiphenyl Compounds Cancer Res 1979;39(9):3369 Cancer Res 35(11):2962;1975 Chem Biol Interact 11(6):599;1975 J Natl Cancer Inst 55(2):285;1975 Oncology 36(3):105;1979 NLM CCR CCR M0041512 N-hydroxy-4-acetylaminobiphenyl C0068028 N-(1,1'- biphenyl)-4-yl-N-hydroxyacetamide 4463-22-3 T109 Organic Chemical T131 Hazardous or Poisonous Substance T071515 N-hydroxy-4-acetylaminobiphenyl T071513 N-hydroxy-N-4-acetylaminobiphenyl T071514 N-hydroxy-N-4-biphenylacetamide C001373 hydroxybenzindazole 1972 01 01 1980 03 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D007191 Indazoles Can J Biochem 50(5):516;1972 NLM TYK NLM M0041528 hydroxybenzindazole C0601076 1H-Benz(g)indazol-7-ol, 4,5-dihydro- 31184-53-9 T071531 hydroxybenzindazole C028409 1,7-dimethyl-2,3,6,7-tetrahydro-1H,5H-biscyclopentapyrazine 1981 03 11 2000 12 15 1998 1999 2000 2001 2001A 2002 obtained from browning reaction of cyclotene ; ammonia under simulated cooking conditions; RN given refers to (cis)-isomer; structure given in first source 1 *D011719 Pyrazines J Agric Food Cehm 1980;28(4):883 RLS WXM WXM M0091479 1,7-dimethyl-2,3,6,7-tetrahydro-1H,5H-biscyclopentapyrazine C0612273 cyclopenta(b,e)pyrazine, 1,2,3,5,6,7-hexahydro-1,7-dimethyl-, cis- 72438-07-4 T109 Organic Chemical T131 Hazardous or Poisonous Substance 72438-06-3 ((trans)-isomer) M0091479 M0317721 T121482 1,7-dimethyl-2,3,6,7-tetrahydro-1H,5H-biscyclopentapyrazine T121480 1,7-DTBCP T121481 cis-1,7-dimethyl-2,3,6,7-tetrahydro-1H,5H-biscyclopentapyrazine M0317721 1,7-dimethyl-2,3,6,7-tetrahydro-1H,5H-biscyclopentapyrazine, (trans)-isomer C0954469 72438-06-3 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0091479 M0317721 T347721 1,7-dimethyl-2,3,6,7-tetrahydro-1H,5H-biscyclopentapyrazine, (trans)-isomer 1999 08 18 C446060 1-(4-fluorophenyl)-2-(4-(phenylsulfonyl)-1-piperidinyl)ethanone 2002 02 06 2002 a 5-HT(2A) receptor antagonist; structure in first source 1 *D010880 Piperidines *D013450 Sulfones D011985 Receptors, Serotonin Q000037 antagonists ; inhibitors J Med Chem 2002 Jan 17;45(2):492-503 THA THA M0413616 1-(4-fluorophenyl)-2-(4-(phenylsulfonyl)-1-piperidinyl)ethanone 0 T109 Organic Chemical T121 Pharmacologic Substance T480928 1-(4-fluorophenyl)-2-(4-(phenylsulfonyl)-1-piperidinyl)ethanone 2002 02 06 T480929 1-FPSP-ethanone 2002 02 06 C028435 2-octopamine 1981 03 16 2000 12 15 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to cpd without isomeric designation 27 *D009655 Octopamine D007536 Isomerism Biomed Mass Spectrom 1980;7(8):349 RLS WXM WXM M0091542 2-octopamine C0046479 2234-25-5 T109 Organic Chemical T124 Neuroreactive Substance or Biogenic Amine 70080-69-2 ((+-)-isomer) 71772-28-6 (HCl(R)-isomer) 71772-29-7 (HCl(S)-isomer) M0091542 M0317737 M0091542 M0317738 M0091542 M0317739 T121545 2-octopamine T121544 ortho-octopamine T121543 alpha-(aminomethyl)-2-hydroxybenzenemethanol M0317737 2-octopamine, (+-)-isomer C0954475 70080-69-2 T109 Organic Chemical T124 Neuroreactive Substance or Biogenic Amine M0091542 M0317737 T347737 2-octopamine, (+-)-isomer 1999 08 18 M0317738 2-octopamine hydrochloride, (R)-isomer C0954476 71772-28-6 T109 Organic Chemical T124 Neuroreactive Substance or Biogenic Amine M0091542 M0317738 T347738 2-octopamine hydrochloride, (R)-isomer 1999 08 18 M0317739 2-octopamine hydrochloride, (S)-isomer C0954477 71772-29-7 T109 Organic Chemical T124 Neuroreactive Substance or Biogenic Amine M0091542 M0317739 T347739 2-octopamine hydrochloride, (S)-isomer 1999 08 18 C001385 S-(9-hydroxy-9,10-dihydro-10-phenanthryl)-L-cysteine 1972 01 01 1982 09 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CYSTEINE (72-75) PHENANTHRENES (72-82) D003545 Cysteine *Q000031 analogs ; derivatives Proc Soc Exptl Biol Med 139(1):173;1972 NLM VSR NLM M0041546 S-(9-hydroxy-9,10-dihydro-10-phenanthryl)-L-cysteine C0601082 25331-33-3 T071549 S-(9-hydroxy-9,10-dihydro-10-phenanthryl)-L-cysteine C001386 25-hydroxydihydrotachysterol(3) 1970 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 3 *VITAMIN D (70-72) HYDROXYSTEROIDS (73-76) SECOSTEROIDS (70-73) D004097 Dihydrotachysterol *Q000031 analogs ; derivatives NLM NLM M0041547 25-hydroxydihydrotachysterol(3) C0046700 9,10-secocholesta-5,7-diene-3 beta,25-diol 25631-39-4 T071550 25-hydroxydihydrotachysterol(3) C446061 1-(4-(4-(2-(1-hydroxyethyl)pyrimidin-4-yl)-2,6-dimethylpiperazin-1-yl)pyrimidin-2-yl)ethanol 2002 02 06 2002 structure in first source 1 *D010879 Piperazines *D011743 Pyrimidines D007064 L-Iditol 2-Dehydrogenase Q000037 antagonists ; inhibitors J Med Chem 2002 Jan 17;45(2):511-28 THA THA M0413617 1-(4-(4-(2-(1-hydroxyethyl)pyrimidin-4-yl)-2,6-dimethylpiperazin-1-yl)pyrimidin-2-yl)ethanol 0 T109 Organic Chemical T121 Pharmacologic Substance T480930 1-(4-(4-(2-(1-hydroxyethyl)pyrimidin-4-yl)-2,6-dimethylpiperazin-1-yl)pyrimidin-2-yl)ethanol 2002 02 06 T480931 2002uglycpd15 2002 02 06 C413004 RFX-AP protein 2000 09 12 2000 2001 2002 the gene responsible for the most common cause of the bare lymphocyte syndrome, an MHC class II immunodeficiency; has been sequenced 5 *D014157 Transcription Factors Mol Cell Biol 2000 Sep;20(17):6587-99 BMB BMB M0369313 RFX-AP protein C0970991 0 T116 Amino Acid, Peptide, or Protein T423774 RFX-AP protein 2000 09 12 T423775 RFX-AP gene product 2000 09 12 T423776 RFXAP gene product 2000 09 12 C413005 pegnartograstim 2000 09 12 2000 2001 2002 MW 20 kDa; RN ; amino acid sequence in first source 1 *D011506 Proteins Clin Pharmacol Ther. 2000 Jul;68(1):105 BMB BMB M0369314 pegnartograstim C0960610 204565-76-4 T114 Nucleic Acid, Nucleoside, or Nucleotide T423777 pegnartograstim 2000 09 12 C001391 nifuratrone 1971 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ALCOHOL, ETHYL (72-75) ALCOHOL, ETHYL/analogs (75-76) NITROGEN OXIDES (72-76) *D009581 Nitrofurans NLM NLM M0041561 nifuratrone C0601083 N-(2-hydroxyethyl)-alpha-(5-nitro-2-furyl)nitrone 19561-70-7 T071564 nifuratrone C001398 estrololactone 1971 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ESTRANES (74-75) *ESTRENES (75-77) *STEROIDS, HETEROCYCLIC (75-76) HOMOSTEROIDS (71-82) PHENANTHRENES (71-72) D004970 Estrone *Q000031 analogs ; derivatives NLM VSR NLM M0041562 estrololactone C0601084 3-hydroxy-D-homo-17a-oxaestra-1,3,5(10)-trien- 17-one 604-82-0 T071565 estrololactone C028438 17 beta-((1R)-1-hydroxy-2-propynyl)androst-4-en-3-one 1981 03 16 2000 12 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to (17beta)-isomer; structure given in first source 2 *D000737 Androstenols Biochemistry 1980;19(22):4950 RLS WXM WXM M0091545 17 beta-((1R)-1-hydroxy-2-propynyl)androst-4-en-3-one C0044974 androst-4-en-3-one, 17-(1-hydroxy-2-propynyl)-, (17 beta(R))- 72012-08-9 T110 Steroid T125 Hormone 72012-07-8 ((17beta)-(S)-isomer) M0091545 M0317740 T121548 17 beta-((1R)-1-hydroxy-2-propynyl)androst-4-en-3-one T121547 17-HPAO M0317740 17 beta-((1R)-1-hydroxy-2-propynyl)androst-4-en-3-one, (17beta)-(S)-isomer C0954478 72012-07-8 T110 Steroid T125 Hormone M0091545 M0317740 T347740 17 beta-((1R)-1-hydroxy-2-propynyl)androst-4-en-3-one, (17beta)-(S)-isomer 1999 08 18 C001792 citroxanthin 1972 01 01 2001 01 25 1997 1998 1999 2000 2001 2001A 2002 1 *CAROTENE (72-75) CAROTENE/*analogs ; derivatives (76-96) ETHERS, CYCLIC (72-75) D019207 beta Carotene *Q000031 analogs ; derivatives Int J Vitam Nutr Res 42(2):278;1972 NLM TWD TWD M0042135 citroxanthin C0601193 5,8-monoepoxy-beta-carotene 515-06-0 T072138 citroxanthin T072137 mutatochrome C028444 methyl lactate 1981 03 17 2000 12 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to cpd without isomeric designation 6 *D007773 Lactates J Chromatogr 1980;202(2):305 RLS WXM WXM M0091552 methyl lactate C0066258 547-64-8 T109 Organic Chemical 17392-83-5 ((+)-isomer) 2155-30-8 ((+-)-isomer) 27871-49-4 ((S)-isomer) M0091552 M0317745 M0091552 M0317746 M0091552 M0317747 T121555 methyl lactate Merck Index, 9th ed, #5959 T121554 methyl 2-hydroxypropionate M0317745 methyl lactate, (+)-isomer C0954483 17392-83-5 T109 Organic Chemical M0091552 M0317745 T347745 methyl lactate, (+)-isomer 1999 08 18 M0317746 methyl lactate, (+-)-isomer C0954484 2155-30-8 T109 Organic Chemical M0091552 M0317746 T347746 methyl lactate, (+-)-isomer 1999 08 18 M0317747 methyl lactate, (S)-isomer C0954485 27871-49-4 T109 Organic Chemical M0091552 M0317747 T347747 methyl lactate, (S)-isomer 1999 08 18 C019303 quinoline yellow 1979 01 01 2002 02 06 1998 1999 2000 2001 2001A 2001B 2002 2002A 14 *D011804 Quinolines Food Cosmet Toxicol 17(1):1;1979 NLM tpw tpw M0071662 quinoline yellow C0054391 8004-92-0 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0071662 M0071663 M0071662 M0071659 M0071662 M0071660 T101665 quinoline yellow M0071663 C.I. acid yellow 3 C0950392 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0071662 M0071663 T101666 C.I. acid yellow 3 M0071659 Colour Index No. 47005 C0525306 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0071662 M0071659 T101662 Colour Index No. 47005 M0071660 D;C Yellow No 10 CT038058 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0071662 M0071660 T101663 D;C Yellow No 10 T480934 D ; C Yellow #10 2002 02 06 T101664 D.C. Yellow No. 10 C025129 FDC blue lake no.2 1980 07 03 2002 02 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 2002A implicated in false positive "hemoccult" reaction with cimetidine use 4 *D004396 Dyes N Engl J Med 1980;303(2):110 MEG tpw tpw M0084144 FDC blue lake no.2 C0060124 0 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T114147 FDC blue lake no.2 T480935 F D ; C blue #2 lake 2002 02 06 C001426 N-hydroxysuccinimide 1972 01 01 1980 02 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 80 *D013388 Succinimides Biochemistry 1979;18(13):2815 Biochim Biophys Acta 1979;565(1):219 Biochim Biophys Acta 438(1):231;1976 J Immunol 114(1):51;1975 Methods Cell Biol 18:429;1978 Z Krebsforsch 76(3):216;1971 NLM RLS NLM M0041619 N-hydroxysuccinimide C0068051 1-hydroxy-2,5-pyrrolidinedione 6066-82-6 T071622 N-hydroxysuccinimide C001438 imidazo(4,5,1-kl)phenoxazine 1970 01 01 1982 09 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 IMIDAZOLES (70-82) *D010078 Oxazines NLM VSR NLM M0041634 imidazo(4,5,1-kl)phenoxazine C0601094 Imidazo(4,5,1-kl)phenothiazine 202-25-5 T071637 imidazo(4,5,1-kl)phenoxazine C001439 imidazo(1,2-a)pyridine 1972 01 01 1982 08 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 9 *IMIDAZOLES (72-82) *D011725 Pyridines Boll Chim Farm 110(6):317;1971 NLM CHA NLM M0041635 imidazo(1,2-a)pyridine C0063377 274-76-0 T071638 imidazo(1,2-a)pyridine C001443 Immobilizine 1971 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ANTIBODIES (71-75) *D000907 Antibodies, Bacterial Res Commun Chem Pathol Pharmacol 11(1):147;1975 NLM NLM M0041648 Immobilizine C0063411 0 T071651 Immobilizine C001451 Innovar 1972 01 01 1997 10 03 1997 1998 1999 2000 2001 2002 combination drug containing fentanyl citrate ; droperidol 87 *BENPERIDOL (72-74) *D004329 Droperidol *D005283 Fentanyl Anesteziol Reanimatol 4:24;1978 Anesth Analg (Cleve) 1980;59(1):50 Can Anaesth Soc J 26(1):29;1979 Ill Med J 140(3):214;1971 Jpn J Anesthesiol 20(10):965;1071 Jpn J Anesthesiol 20(10):973;1971 Masui 28(4):356;1979 Rev Esp Anestesiol Reanim 23(5):390;1976 West Afr J Pharmacol Drug Res 2(1):73;1975 Z Gastroenterol 16(11):696;1978 NLM MLH BVL M0041664 Innovar C0063549 N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide. 2-hydroxy-1,2,3-propanetricarboxylate mixt. with 1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6- tetrahydro-4-pyridinyl)-1,3-dihydro-2H-benzimidazol- 2-one 8067-59-2 D000700 Analgesics D019162 Anesthetics, Combined M0041664 M0041660 M0041664 M0041661 M0041664 M0041659 M0041664 M0041663 M0041664 M0041662 T071667 Innovar UD 18:46h M0041660 Thalamonal C0145526 M0041664 M0041660 T071663 Thalamonal M0041661 fentanyl-droperidol C0117480 M0041664 M0041661 T071664 fentanyl-droperidol M0041659 Innovar-Vet C0123569 M0041664 M0041659 T071662 Innovar-Vet M0041663 talamonal C0144475 M0041664 M0041663 T071666 talamonal M0041662 leptofen C0125482 M0041664 M0041662 T071665 leptofen C001535 leucylnegamycin 1972 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from negamycin-producing Streptomyces; structure 0 *ANTIBIOTICS (72-76) *DIPEPTIDES (72-76) *HYDRAZINES (72-76) AMINOCAPROIC ACID (72-75) LEUCINE (72-75) D000599 Amino Acids, Diamino J Antibiot (Tokyo) 24(10):732;1971 NLM TWD TWD M0041770 leucylnegamycin C0601116 35663-84-4 M0041770 M0041769 T071773 leucylnegamycin M0041769 (2-(3(R)-amino-5(R)-hydroxy-6-L-leucylaminohexanoyl)-1-methylhydrazino)acetic acid C0601115 M0041770 M0041769 T071772 (2-(3(R)-amino-5(R)-hydroxy-6-L-leucylaminohexanoyl)-1-methylhydrazino)acetic acid C001527 Ledermix 1972 01 01 2000 12 13 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 contains above two cpds 40 *D003707 Demeclocycline *D014222 Triamcinolone Acetonide D004338 Drug Combinations J Br Endod Soc 6(1):8;1972 NLM CCR CCR M0041756 Ledermix C0064736 8059-68-5 T109 Organic Chemical T122 Biomedical or Dental Material T071759 Ledermix C001463 iodoindoxyl phosphate 1971 01 01 1998 01 05 1998 1999 2000 2001 2002 0 IODIDES (71-72) IODINE (72-76) ORGANOPHOSPHORUS COMPOUNDS (71-82) PHOSPHORIC ACIDS (71-74) *D007211 Indoles NLM IDX BVL M0041675 iodoindoxyl phosphate C0601103 5-iodo-1H-indol-3-ol dihydrogen phosphate ester 7300-58-5 T071678 iodoindoxyl phosphate C053369 ascites microvillar protein p35 1987 09 15 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 major calcium-sensitive protein from microvilli of mammary ascites tumor cells; binds phenothiazine in absence of calcium; MW 35kDa 2 *D008840 Microfilament Proteins *D009363 Neoplasm Proteins FASEB J 1987;1(1):46 RLS WXM WXM M0151155 ascites microvillar protein p35 C0208650 0 T181160 ascites microvillar protein p35 T181159 AMV p35 C001472 iridine 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 protamine from rainbow trout Salmo irideus 1 *D011479 Protamines Int J Pept Protein Res 1(3):221;1969 NLM NLM M0041682 iridine C0063854 Iridine 67255-34-9 T071685 iridine Merck Index, 9th ed, p. 1021, in #7669 C001477 isolichenin 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D011134 Polysaccharides J Biol Chem 246(22):6722;1971 NLM NLM M0041691 isolichenin C0601106 11014-35-0 T071694 isolichenin C097151 Bloom syndrome protein 1996 01 19 2000 12 20 1999 2000 2001 2001A 2002 homologous to E. coli RecQ helicase and human REQL protein; 1 1417 amino acid peptide; amino acid sequence known 85 *D000251 Adenosinetriphosphatase *D004265 DNA Helicases D001816 Bloom Syndrome Nature 1995 Dec 7;378(6557):557-8 PML CCR CCR M0255407 Bloom syndrome protein C0384701 EC 3.6.1.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T285412 Bloom syndrome protein T285410 BLM gene product T285411 BLM protein C027093 DNA Helicase I 1980 11 26 2000 12 20 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 enzyme capable of unwinding DNA at the expense of ATP; from E. coli; TraI gene product of E coli F factor; nicks and unwinds the F plasmid 71 *D004265 DNA Helicases D004720 Endonucleases J Biol Chem 1980;255(20):9746 NLM CCR CCR M0088366 DNA Helicase I C0058545 EC 3.1.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T118369 DNA Helicase I T118366 Helicase I, DNA T118367 TraI gene product T118368 TraI protein C001490 3-isothiazolone 1972 01 01 1993 02 08 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 has inhibitory effect on human cancer cells in vitro; structure; active ingredient of biocide Kathon 3 KETONES (72-74) *D013844 Thiazoles Acta Cytol (Baltimore) 15(4):325;1971 NLM RLS NLM M0041708 3-isothiazolone C0206782 3(2H)-isothiazolone 1003-07-2 T071711 3-isothiazolone C001492 juglomycin 1971 01 01 1983 06 21 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 LACTONES (72-76) D009285 Naphthoquinones Jap J Antibiot 24(5):222;1971 NLM JSL NLM M0041709 juglomycin C0064169 Juglomycin 77904-45-1 T071712 juglomycin C001493 kanchanomycin 1971 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D000903 Antibiotics, Antineoplastic Biochemistry 9(22):4421;1970 NLM NLM M0041710 kanchanomycin C0064233 1403-85-6 T071713 kanchanomycin C053630 serotonin-binding protein kinase 1987 10 16 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 an aspect of protein kinases EC 2.7.1.37 1 *D011494 Protein Kinases J Neurochem 1987;49(4):1105 RLS WXM WXM M0151850 serotonin-binding protein kinase C0631748 EC 2.7.1.- T181855 serotonin-binding protein kinase T181854 SBP kinase C001497 kavaform 1971 01 01 1981 06 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 complex geriatric analeptic; each tablet contains (+-)-kavain 50mg, magnesium orotate 200mg, silicic acid 10mg, carriec 370mg ; extract of vitis viniferae rubr. 50mg 1 *PYRANS (71-81) *SILICA (71-75) *D009963 Orotic Acid *D011753 Pyrones *D012824 Silicic Acid D004338 Drug Combinations Z Alternsforsch 29(3):311;1975 NLM NBM NLM M0041715 kavaform C0064259 8074-25-7 T071718 kavaform UD 18:106c C001502 7-keto-8-aminopelargonic acid 1972 01 01 1977 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 3 *FATTY ACIDS (72-77) KETO ACIDS (72-75) *D000596 Amino Acids Biochim Biophys Acta 264(1):210;1972 NLM NLM M0041719 7-keto-8-aminopelargonic acid C0049919 8-amino-7-oxononanoic acid 4707-58-8 T071722 7-keto-8-aminopelargonic acid C053803 hemeprotein b-559 1987 11 04 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 MW 78kDa; from Bengal-gram seeds 1 *D006420 Hemeproteins Biochem J 1987;243(3):723 RLS WXM WXM M0152237 hemeprotein b-559 C0631872 0 T182242 hemeprotein b-559 T182241 haemoprotein b-559 C001510 kromycin 1972 01 01 1981 01 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 anhydro aglycone of antibiotic pikromycin 0 D007783 Lactones J Am Chem Soc 92(26):7286;1971 NLM BEJ NLM M0041736 kromycin C0064418 ((3R-(3R*,5E,7S*,9R*,11E,13S*,14R*))-14-ethyl-13-hydroxy-3,5,7,9,13-pentamethyloxacyclotetradeca-5,11-diene-2,4,10-trione) 20509-23-3 T071739 kromycin C001900 2,5-anhydro-D-mannitol-1,6-diphosphate 1973 01 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 *HEXOSEDIPHOSPHATES (73-78) *MANNITOL (73-78) *D008355 Mannitol Phosphates Arch Biochem Biophys 152(10):272;1972 NLM TWD TWD M0042305 2,5-anhydro-D-mannitol-1,6-diphosphate C0045539 671-08-9 T072308 2,5-anhydro-D-mannitol-1,6-diphosphate T072307 2,5-anhydro-D-mannitol-1,6-bisphosphate C053834 insulin secretory granule membrane glycoprotein 110 1987 11 10 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 MW 110kDa; from insulin secretory granule; used to study granule biogenesis 2 *D008562 Membrane Glycoproteins D007328 Insulin Biochem J 1987;245(2):567 RLS WXM WXM M0152327 insulin secretory granule membrane glycoprotein 110 C0063614 0 T182332 insulin secretory granule membrane glycoprotein 110 T182331 SGM 110 C001522 laudanosine 1972 01 01 1998 09 16 1998 1999 2000 2001 2002 opium alkaloid 87 BENZYL COMPOUNDS (72-76) *D007546 Isoquinolines D009892 Opium J Org Chem 41(15):2548;1976 J Pharm Sci 60(11):1672;1971 NLM SZM NLM M0041746 laudanosine C0064679 2688-77-9 D002491 Central Nervous System Agents T071749 laudanosine C053835 hemoglobin Hobart 1987 11 10 2001 01 25 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 His replaced by Arg in position 20(B1) on alpha chain 1 *D006455 Hemoglobins, Abnormal Hemoglobin 1987;11(3):211 RLS WXM WXM M0152329 hemoglobin Hobart C0313282 Hemoglobin Hobart 111417-21-1 T182334 hemoglobin Hobart T182333 Hb Hobart C091458 5-decenoyl-coenzyme A 1995 02 10 2001 01 25 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 *D000214 Acyl Coenzyme A Biochemistry 1995 Jan 17;34(2):442-50 BMB CCR CCR M0241527 5-decenoyl-coenzyme A C0293050 0 M0241527 M0241525 T271532 5-decenoyl-coenzyme A T271531 coenzyme A, 5-decenoyl- M0241525 cis-5-decenoyl-CoA C0293049 M0241527 M0241525 T271530 cis-5-decenoyl-CoA C001902 cyclic 9 beta-D-arabinosyladenine 3',5'-monophosphate 1973 01 01 2001 01 25 1996 1997 1998 1999 2000 2001 2001A 2002 structure 1 *CYCL AMP (73-79) *NUCLEOTIDES, CYCLIC (73-82) ARABINOSE (73-79) ARABINOSE/analogs (75-79) CYCL AMP/*analogs (75-79) D001084 Vidarabine Phosphate *Q000031 analogs ; derivatives Cancer Res 32(9):1791;1972 J Med Chem 17(3):259;1974 NLM TWD TWD M0042307 cyclic 9 beta-D-arabinosyladenine 3',5'-monophosphate C0056691 32465-18-2 T072310 cyclic 9 beta-D-arabinosyladenine 3',5'-monophosphate T072309 9 beta-D-arabinofuranosyladenine cyclic 3',5'-phosphate C001542 liatrin 1974 01 01 1981 11 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 antileukemic sesquiterpene lactone from Liatris chapmani 0 *ANTINEOPLASTIC AGENTS (74-79) LACTONES (74-81) PLANT EXTRACTS (74-76) *D012717 Sesquiterpenes J Am Chem Soc 93(19):4916;1971 NLM NBM NLM M0041776 liatrin C0601118 34175-79-6 T071779 liatrin C001553 Lomapect 1972 01 01 1982 09 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination drug; contains prenoxdiazine ; diphenhydramine 0 *D004155 Diphenhydramine *D010069 Oxadiazoles D004338 Drug Combinations Med Welt 46:1855;1971 NLM VSR NLM M0041786 Lomapect C0601121 0 T071789 Lomapect C001560 lutean 1971 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D011134 Polysaccharides NLM NLM M0041791 lutean C0601122 39409-41-1 T071794 lutean C001563 Lysoneuro 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *D009419 Nerve Tissue Proteins Minerva Med 63(2):49-167;1972 NLM NLM M0041795 Lysoneuro C0065388 11121-86-1 T071798 Lysoneuro C001571 gamma-aminobutyrylcholine 1972 01 01 1980 10 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *AMINOBUTYRIC ACIDS (72-76) *CHOLINE (72-75) GABA/analogs (76-81) D002794 Choline *Q000031 analogs ; derivatives J Neurochem 30(6):1461;1978 J Pharm Pharmacol 24(3):251;1972 J Pharm Pharmacol 27:529;1975 Trans Am Neurol Assn 99:50;1974 NLM RLS NLM M0041802 gamma-aminobutyrylcholine C0061027 541-18-4 T071805 gamma-aminobutyrylcholine C001586 N-benzyl salsolidine 1972 01 01 1980 12 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ALKALOIDS (72-79) *ISOQUINOLINES (72-79) BENZYL COMPOUNDS (72-76) *D012490 Salsoline Alkaloids Arch Int Pharmacodyn Ther 196:106;1972 NLM BEJ NLM M0041828 N-benzyl salsolidine C0067829 1-methyl-2-benzyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 19902-16-0 T071831 N-benzyl salsolidine C001587 bimetopyrol 1972 01 01 1986 08 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ANISOLES (72-81) *D011758 Pyrroles J Pharm Soc Jap 92(3):305;1972 NLM THA NLM M0041829 bimetopyrol C0053606 2-methyl-4,5-bis(p-methoxyphenyl)pyrrole 30011-11-1 T071832 bimetopyrol C001590 1,4-3,6-bis(thioanhydro)-D-iditol 1972 01 01 1984 10 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 potential antineoplastic agents; structure 0 SULFIDES (72-76) *D013402 Sugar Alcohols Carbohyd Res 21(1):19;1972 NLM DLJ NLM M0041833 1,4-3,6-bis(thioanhydro)-D-iditol C0601127 D-Iditol, 1,3,4,6-tetradeoxy-1,4:3,6-diepithio- 35396-08-8 T071836 1,4-3,6-bis(thioanhydro)-D-iditol C001663 macroamylase 1972 01 01 2000 09 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 abnormally large serum amylase bound to globulin; causes macroamylasemia 78 SERUM GLOBULINS (73-80) *D000681 Amylases D008261 Macromolecular Systems Am J Surg 135(4):488;1978 Ann Biol Clin (Paris) 37(3):167;1979 Clin Biochem 1980;13(1):46 Gastroenterology 63(4):564;1972 Klin Wochenschr 50(11):548;1972 Lancet 1980;1(8170):680 NLM CCR CCR M0041932 macroamylase C0065478 EC 3.2.1.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T071935 macroamylase C001595 carbobiotin 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 *BIOTIN (72-76) *CYCLOPENTANES (72-76) D001710 Biotin *Q000031 analogs ; derivatives NLM NLM M0041841 carbobiotin C0601131 cis-hexahydro-4-(4-carboxybutyl)-2-cyclopentimidazolone 37842-47-0 T071844 carbobiotin C010158 amafolone 1976 01 01 2000 09 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 RN given refers to parent cpd; NM refers to HCl 16 *ANDROSTANES (76-80) 17-KETOSTEROIDS (76-80) *D000732 Androstanols Arzneim Forsch 26(8):1558;1976 Br J Pharmacol 1979;66(3):463P Br J Pharmacol 1980;68(1):25 Br J Pharmacol 55(3):359;1975 Br J Pharmacol 57:251;1976 Br J Pharmacol 61(2):315;1977 Br J Pharmacol 61(3):457;1977 Br J Pharmacol 66(4):609;1979 Dtsch Med Wochenschr 1980;105(6):189 Eur J Pharmacol 36(1):189;1976 Eur J Pharmacol 49(1):81;1978 J Chromatogr 1979;162(3):422 J Pharm Pharmacol 27(9):697;1975 J Pharmacol Exp Ther 204(3):623;1978 Prostaglandins 1979;18(5):707 NLM CCR CCR M0055465 amafolone C0069619 (2 beta,3 alpha,5 alpha)-3-amino-2-hydroxyandrostan-17-one, hydrochloride 50588-47-1 T110 Steroid T121 Pharmacologic Substance 51740-76-2 (HCl) M0055465 M0311054 M0055465 M0055462 T085468 amafolone T085467 amafalone M0311054 amafolone hydrochloride C0094094 51740-76-2 T110 Steroid T121 Pharmacologic Substance M0055465 M0311054 T341054 amafolone hydrochloride 1999 08 18 T085464 3 alpha-amino-5 alpha-androstan-2 beta-ol-17-one.HCl M0055462 Org 6001 C0134079 T110 Steroid T121 Pharmacologic Substance M0055465 M0055462 T085465 Org 6001 T085466 Org-6001 C054830 glycoprotein BCA 225 1988 03 16 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 MW 225 kDa-250 kDa; found mainly in clone of 11T47D breast carcinoma cells; recognized by monoclonal antibodies CU18, CU26 ; CU46 1 *D006023 Glycoproteins D014408 Tumor Markers, Biological Am J Pathol 1988;130(2):305 RLS WXM WXM M0154638 glycoprotein BCA 225 C0632750 0 T184643 glycoprotein BCA 225 T184642 glycoprotein BCA-225 C001610 5-deoxypyridoxamine 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PYRIDOXAMINE (72-75) D011733 Pyridoxamine *Q000031 analogs ; derivatives Biochemistry 11(15):2911;1972 NLM NLM M0041866 5-deoxypyridoxamine C0601136 20485-33-0 T071869 5-deoxypyridoxamine C001611 dibenzo-30-crown-10 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 BENZENE DERIVATIVES (72-76) *D004988 Ethers, Cyclic Acta Pharm Suec 13(2):190;1976 Proc Nat Acad Sci USA 69(7):1939;1972 NLM NLM M0041867 dibenzo-30-crown-10 C0057774 17455-25-3 T071870 dibenzo-30-crown-10 C101399 AQ 0145 1996 10 22 2000 09 18 1997 1998 1999 2000 2000A 2001 2002 structure given in first source 1 *D000578 Amidines *D007093 Imidazoles D000218 Adamantane *Q000031 analogs ; derivatives D018100 Receptors, Histamine H3 Q000037 antagonists ; inhibitors Methods Find Exp Clin Pharmacol 1995 Nov;17 Suppl C:70-3 RMK TWD TWD M0265829 AQ 0145 C0529739 0 T109 Organic Chemical T121 Pharmacologic Substance M0265829 M0265828 T295834 AQ 0145 T295831 AQ-0145 T295832 AQ0145 M0265828 N-1-adamantyl-N'N'(1,5-(3-(4(5)-1H-imidazolyl))-pentanediyl)formamidine dihydrochloride C0529741 T109 Organic Chemical T121 Pharmacologic Substance M0265829 M0265828 T295833 N-1-adamantyl-N'N'(1,5-(3-(4(5)-1H-imidazolyl))-pentanediyl)formamidine dihydrochloride C054836 protein C propeptide 1988 03 16 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 pro-portion of the leader sequence is 24-amino acids in length; do not confuse with pre-portion which is 18 amino acids in length 2 *D011486 Protein C *D011498 Protein Precursors Biochemistry 1987;26(22):7003 RLS WXM WXM M0154665 protein C propeptide C0632777 0 T184670 protein C propeptide T184669 propeptide protein C C001616 6-dimethylaminonicotinamide 1972 01 01 1992 06 18 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *NICOTINAMIDE (72-75) DIMETHYLAMINES (73-76) D009536 Niacinamide *Q000031 analogs ; derivatives J Med Chem 15(8):849;1972 NLM MLH TPW M0041876 6-dimethylaminonicotinamide C0601137 36507-21-8 T071879 6-dimethylaminonicotinamide C054897 avian retrovirus nucleocapsid protein 1988 03 21 2001 01 25 1997 1998 1999 2000 2001 2001A 2002 5 *D002213 Capsid *D014758 Viral Core Proteins D001355 Alpharetrovirus D012191 Retroviridae Proteins J Biol Chem 1988;263(5):2134 RMK WXM WXM M0154821 avian retrovirus nucleocapsid protein C0052706 0 T184826 avian retrovirus nucleocapsid protein T184825 NR protein pp12 C001618 dimethylquinazolone 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 analog of METHAQUALONE 0 *QUINAZOLINES (72-75) D008702 Methaqualone *Q000031 analogs ; derivatives Brit J Pharmacol 44(4):805;1972 NLM NLM M0041878 dimethylquinazolone C0601138 1769-25-1 T071881 dimethylquinazolone C101347 4-hydroxybutyryl-coenzyme A 1996 10 21 2001 01 25 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 2 *D000214 Acyl Coenzyme A Biochemistry 1996 Sep 10;35(36):11710-8 BMB CCR CCR M0265728 4-hydroxybutyryl-coenzyme A C0529644 0 T295733 4-hydroxybutyryl-coenzyme A T295731 4-hydroxybutyryl-CoA T295732 coenzyme A, 4-hydroxybutyryl- C055002 GAL80 protein, Saccharomyces 1988 03 29 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from GAL80 gene of Saccharomyces cerevisiae; encodes a protein that binds directly to GAL4 protein, preventing it from activating transcription 46 *D005656 Fungal Proteins D012097 Repressor Proteins Microbiol Rev 1987;51(4):458 RLS WXM WXM M0155062 GAL80 protein, Saccharomyces C0060950 0 T185067 GAL80 protein, Saccharomyces T185066 GAL80 Sacch protein C102828 methylsuccinyl-coenzyme A 1997 01 15 2001 01 25 1997 1998 1999 2000 2001 2001A 2002 product of methylmalonyl-CoA mutase rearrangement of glutaryl-CoA; structure in first source 2 *D000214 Acyl Coenzyme A Biofactors 1995-1996;5(2):83-6 BVL CCR CCR M0269051 methylsuccinyl-coenzyme A C0532601 0 T299056 methylsuccinyl-coenzyme A T299054 MeSuc-CoA T299055 methylsuccinyl-CoA C001629 N-ethyl-N-butylnitrosamine 1972 01 01 1985 07 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 *NITROSAMINES (72-75) D004052 Diethylnitrosamine *Q000031 analogs ; derivatives Z Krebsforsch 77(3):189;1972 NLM LCR NLM M0041889 N-ethyl-N-butylnitrosamine C0067956 4549-44-4 T071892 N-ethyl-N-butylnitrosamine C001631 N,N'-ethylenebis(5-(2-bromoethylthio)valeramide) 1972 01 01 1982 09 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 AMIDES (72-76) VALERATES (72-82) *D009150 Mustard Compounds J Pharmacol Exp Ther 182(1):77;1972 NLM VSR NLM M0041890 N,N'-ethylenebis(5-(2-bromoethylthio)valeramide) C0601141 870-03-1 T071893 N,N'-ethylenebis(5-(2-bromoethylthio)valeramide) C055048 glycoprotein GP98, guinea pig macrophage 1988 04 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 MW 98 kDa; guinea pig macrophage-specific polymorphic molecule 2 *D006023 Glycoproteins J Immunol 1988;140(4):1198 TPW WXM WXM M0155152 glycoprotein GP98, guinea pig macrophage C0061680 0 T185157 glycoprotein GP98, guinea pig macrophage T185156 GP98 glycoprotein C001635 ferroin 1972 01 01 1998 06 30 1998 1999 2000 2001 2002 RN given refers to parent cpd 35 *D010618 Phenanthrolines Acta Soc Ophthalm Jap 76(3):150;1972 NLM SXK NLM M0041901 ferroin C0060269 14708-99-7 D000935 Antifungal Agents D007202 Indicators and Reagents D007364 Intercalating Agents 14586-54-0 (diperchlorate) 14634-91-4 (sulfate[1:1]) M0041901 M0041900 M0041901 M0041898 M0041901 M0041899 M0041901 M0307710 M0041901 M0307711 T071904 ferroin Merck Index 8th Edn p. 804 M0041900 ortho-phenanthroline C0134184 M0041901 M0041900 T071903 ortho-phenanthroline M0041898 Fe(phen)3 C0117409 M0041901 M0041898 T071901 Fe(phen)3 M0041899 iron(II) 1,10-phenanthroline C0123954 M0041901 M0041899 T071902 iron(II) 1,10-phenanthroline M0307710 diperchlorate of ferroin C0894048 14586-54-0 M0041901 M0307710 T337710 diperchlorate of ferroin 1999 08 18 M0307711 sulfate[1:1] of ferroin C0894049 14634-91-4 M0041901 M0307711 T337711 sulfate[1:1] of ferroin 1999 08 18 C001643 glomerular sialoprotein 1972 01 01 1986 03 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 51 *GLYCOPROTEINS (72-86) NEURAMINIC ACIDS (72-75) SIALIC ACIDS (72-82) *D012795 Sialoglycoproteins Am J Pathol 68(2):391;1972 NLM RLS NLM M0041907 glomerular sialoprotein C0061340 0 M0041907 M0041904 M0041907 M0041905 M0041907 M0041906 T071910 glomerular sialoprotein M0041904 glomerular mucosubstance C0119306 M0041907 M0041904 T071907 glomerular mucosubstance M0041905 glomerular polyanion C0119307 M0041907 M0041905 T071908 glomerular polyanion M0041906 podocalyxin C0137431 M0041907 M0041906 T071909 podocalyxin C102829 ethylmalonyl-coenzyme A 1997 01 15 2001 01 25 1997 1998 1999 2000 2001 2001A 2002 product of methylmalonyl-CoA mutase rearrangement of glutaryl-CoA, structure in first source 5 *D000214 Acyl Coenzyme A Biofactors 1995-1996;5(2):83-6 BVL CCR CCR M0269054 ethylmalonyl-coenzyme A C0532604 0 T299059 ethylmalonyl-coenzyme A T299058 ethylmalonyl-CoA T299057 EtMal-CoA C001651 hippuryl-L-phenylacetate 1972 01 01 1982 10 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PHENYLACETATES (72-82) *D006626 Hippurates Eur J Biochem 25(3):416;1972 NLM VSR NLM M0041918 hippuryl-L-phenylacetate C0601144 Propanoic acid, 2-(((benzoylamino)acetyl)oxy)-, phenyl ester, (S)- 35935-30-9 T071921 hippuryl-L-phenylacetate C055049 myeloma protein Rou 1988 04 01 2001 01 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 human IgA2 myeloma protein; carries isoallotype marker A2m(2) 1 *D009194 Myeloma Proteins J Immunol 1988;140(4):11236 TPW WXM WXM M0155154 myeloma protein Rou C0632988 0 T185159 myeloma protein Rou T185158 IgA2 myeloma protein Rou C001750 Lu 5-003 1971 01 01 2001 08 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 7 METHYLAMINES (71-76) *D013876 Thiophenes Experientia 27(8):927;1971 Psychopharmacology (Berlin) 52:177;1977 NLM TWD TWD M0042067 Lu 5-003 C0065221 21489-20-3 25487-28-9 (HCl) M0042067 M0042065 M0042067 M0042066 T072070 Lu 5-003 M0042065 1-(3-methylaminopropyl)-1-phenyl-3,3-dimethylthiophthalane hydrochloride C0950165 M0042067 M0042065 T072068 1-(3-methylaminopropyl)-1-phenyl-3,3-dimethylthiophthalane hydrochloride T337740 Lu 5-003 hydrochloride 1999 08 18 M0042066 talsupram C0144486 M0042067 M0042066 T072069 talsupram C001673 fluorescein mercuric acetate 1973 01 01 1980 02 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 important as a mercurial 24 *MERCURY (73-77) *ORGANOMETALLIC COMPOUNDS (73-77) *D005452 Fluoresceins *D009941 Organomercury Compounds Biochim Biophys Acta 454(2):309;1976 Biochim Biophys Acta 550(10):16;1979 J Biochem (Tokyo) 85(2):359;1979 J Biochem 81:971;1977 J Biol Chem 1980;255(2):459 J Biol Chem 248(10):3546;1973 JBC 253(12):4279;1978 NLM MEG NLM M0041944 fluorescein mercuric acetate C0060532 3570-80-7 T071947 fluorescein mercuric acetate C001685 matchamycin 1970 01 01 1987 03 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 antibiotic produced by Streptomyces E-753 0 D009942 Organometallic Compounds D003300 Copper J Antibiot 23(9):461;1970 NLM PEH NLM M0041957 matchamycin C0601149 65454-21-9 T071960 matchamycin C046470 MDL 19744A 1985 10 15 2001 08 20 1998 1999 2000 2001 2001A 2002 RN ; structure given in first source; RN given refers to (+-)-free base 1 *D013876 Thiophenes J Med Chem 1985;28(9):1142 RLS TWD TWD M0134619 MDL 19744A C0625188 97233-26-6 97275-04-2 ((+-)-isomer) M0134619 M0322455 M0134619 M0134617 T164624 MDL 19744A T164623 MDL-19,744A M0322455 MDL 19744A, (+-)-isomer C0956862 97275-04-2 M0134619 M0322455 T352455 MDL 19744A, (+-)-isomer 1999 08 18 M0134617 6,7-dihydro-5-(((2-hydroxy-3-phenoxycyclopentyl)amino)methyl)-2-methylbenzo(b)thiophen-4(5H)-one C0625186 M0134619 M0134617 T164622 6,7-dihydro-5-(((2-hydroxy-3-phenoxycyclopentyl)amino)methyl)-2-methylbenzo(b)thiophen-4(5H)-one C094435 GEA 5016 1995 08 04 2001 08 20 1999 2000 2001 2001A 2002 1 *D014230 Triazoles J Physiol Pharmacol 1995 Mar;46(1):37-44 BMB CCR CCR M0248818 GEA 5016 C0299332 0 M0248818 M0248815 T278823 GEA 5016 T278821 GEA-5016 T278822 GEA5016 M0248815 1,2,3,4-oxatriazolum, 5-amino-3-(4-chloro-3-(trifluoromethyl)phenyl)chloride C0299330 M0248818 M0248815 T278820 1,2,3,4-oxatriazolum, 5-amino-3-(4-chloro-3-(trifluoromethyl)phenyl)chloride C001711 mercury phenate 1971 01 01 1977 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *MERCURY (71-77) *ORGANOMETALLIC COMPOUNDS (71-77) PHENOLS (72-76) *D010663 Phenylmercury Compounds NLM NLM M0041993 mercury phenate C0601157 0 T071996 mercury phenate C001712 Mescembran 1971 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 aids in wound healing 0 *D014020 Tissue Extracts J Osaka Univ Dent Soc 16(1):49;1971 NLM NLM M0041994 Mescembran C0601158 0 T071997 Mescembran C073485 kaempferol-3-O-(rhamnopyranosyl-rhamnopyranosyl-(1-6)-galactoside) 1992 04 13 2001 06 06 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from Sesbania sesban; structure given in first source 1 *D014312 Trisaccharides D011794 Quercetin *Q000031 analogs ; derivatives Pharmazie 1991 Sep 46(9):679-80 RLS TWD TWD M0198693 kaempferol-3-O-(rhamnopyranosyl-rhamnopyranosyl-(1-6)-galactoside) C0650426 0 T228698 kaempferol-3-O-(rhamnopyranosyl-rhamnopyranosyl-(1-6)-galactoside) T228697 KRRG C001718 metamidoline 1972 01 01 1982 07 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ANILINE COMPOUNDS (73-76) PIPERIDINES (72-82) *D007211 Indoles Riv Sper Freniatr 95(6):1126;1971 NLM VSR NLM M0042012 metamidoline C0066049 1-oxo-2-methyl-3-aminophenyl-p-ethoxy-piperidinoisoindoline 0 T072015 metamidoline C001787 phenamidine 1972 01 01 2001 02 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 5 *AMIDINES (72-79) *PHENYL ETHERS (79-82) *D001550 Benzamidines Onderstepoort J Vet Res 37(3):173;1970 NLM CCR CCR M0042120 phenamidine C0070532 101-62-2 5421-89-6 (di-HCl) M0042120 M0307747 T072123 phenamidine T072122 di(4-amidinophenyl)ether M0307747 phenamidine dihydrochloride C0951071 5421-89-6 M0042120 M0307747 T337747 phenamidine dihydrochloride 1999 08 18 C094434 GEA 3198 1995 08 04 2001 08 20 1999 2000 2001 2001A 2002 1 *D014230 Triazoles J Physiol Pharmacol 1995 Mar;46(1):37-44 BMB CCR CCR M0248814 GEA 3198 C0299329 0 M0248814 M0248811 T278819 GEA 3198 T278817 GEA-3198 T278818 GEA3198 M0248811 1,2,3,4-oxatriazolum, 3-(2-pyridyl)-5-((1-methylpropyl)amino)chloride C0299327 M0248814 M0248811 T278816 1,2,3,4-oxatriazolum, 3-(2-pyridyl)-5-((1-methylpropyl)amino)chloride C049483 3,4-dihydroxysulfolane 1986 08 12 2001 08 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 *D013876 Thiophenes Eksp Onkol 1986;8(3):75 THA TWD TWD M0141750 3,4-dihydroxysulfolane C0628015 33967-48-5 14176-47-7 ((trans)-isomer) M0141750 M0322837 T171755 3,4-dihydroxysulfolane T171753 3,4-dioxysulfolane T171754 doxilane-diolane M0322837 3,4-dihydroxysulfolane, (trans)-isomer C0957074 14176-47-7 M0141750 M0322837 T352837 3,4-dihydroxysulfolane, (trans)-isomer 1999 08 18 C001732 4-methoxy-6-hydroxybenzofuran-5-carboxamide 1971 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 AMIDES (71-75) FORMAMIDES (75-76) *D001572 Benzofurans NLM NLM M0042031 4-methoxy-6-hydroxybenzofuran-5-carboxamide C0601162 0 T072034 4-methoxy-6-hydroxybenzofuran-5-carboxamide C001740 6-methoxy-2-nonaprenylphenol 1972 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 METHYL ETHERS (72-76) TERPENES (72-82) *D010636 Phenols Biochemistry 11(5):896;1972 NLM VSR NLM M0042041 6-methoxy-2-nonaprenylphenol C0601163 10232-06-1 T072044 6-methoxy-2-nonaprenylphenol C001742 SC 3123 1972 01 01 1994 06 14 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *AMIDINES (72-82) METHYL ETHERS (72-76) *D007546 Isoquinolines Boll Chim Farm 111(6):353;1972 NLM PML TPW M0042045 SC 3123 C0601167 N-(2-o-methoxyphenoxyethyl)-6,7-dimethoxy- 3,4-dihydro-2-(1H)-isoquinoline carboxamidine 36576-29-1 T072048 SC 3123 C087983 invected protein 1994 07 25 2001 02 08 1995 1996 1997 1998 1999 2000 2001 2001A 2002 has been sequenced 13 *D014157 Transcription Factors D007301 Insect Hormones Science 1994 Jul 1;265(5168):109-14 THA WXM WXM M0232928 invected protein C0256278 0 T262933 invected protein T262932 invected gene product C065325 MDL 19660 1990 09 13 2001 08 20 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 4 *D014230 Triazoles Neuropharmacology 1990;29(6):555 TPW CCR CCR M0179663 MDL 19660 C0083362 110623-24-0 M0179663 M0179660 T209668 MDL 19660 T209666 MDL 19,660 T209667 MDL-19660 M0179660 5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3H-1,2,4-triazole-3-thione C0098041 M0179663 M0179660 T209665 5-(4-chlorophenyl)-2,4-dihydro-2,4-dimethyl-3H-1,2,4-triazole-3-thione C031129 7-oxa-13-prostynoic acid 1981 08 19 2000 12 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 potentiates prostaglandin E(2)-induced release of LH; RN given refers to cpd without isomeric designation 3 *D005231 Fatty Acids, Unsaturated Acta Endocrinol 1981;97(3):297 RLS WXM WXM M0098027 7-oxa-13-prostynoic acid C0049960 22707-29-5 T119 Lipid T123 Biologically Active Substance 22662-17-5 ((trans)-isomer) 27166-04-7 ((1S-trans)-isomer) 32567-98-9 ((trans-(+))-isomer) M0098027 M0319111 M0098027 M0319110 M0098027 M0319112 T128031 7-oxa-13-prostynoic acid M0319111 7-oxa-13-prostynoic acid, (1S-trans)-isomer C0955106 27166-04-7 T119 Lipid T123 Biologically Active Substance M0098027 M0319111 T349111 7-oxa-13-prostynoic acid, (1S-trans)-isomer 1999 08 18 M0319110 7-oxa-13-prostynoic acid, (trans)-isomer C0955105 22662-17-5 T109 Organic Chemical T123 Biologically Active Substance M0098027 M0319110 T349110 7-oxa-13-prostynoic acid, (trans)-isomer 1999 08 18 M0319112 7-oxa-13-prostynoic acid, (trans-(+))-isomer C0955107 32567-98-9 T109 Organic Chemical T123 Biologically Active Substance M0098027 M0319112 T349112 7-oxa-13-prostynoic acid, (trans-(+))-isomer 1999 08 18 C031146 maltoheptaose 1981 08 20 2000 12 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 consists of seven glucose residues in a linear 1,4-alpha-linkage; substrate for determining alpha-amylase in serum; RN given refers to (D-glucopyranose)-isomer 37 *D005936 Glucans J Chromatogr 1981;223(1):69 RLS WXM WXM M0098069 maltoheptaose C0065603 1980-14-9 T118 Carbohydrate T130 Indicator, Reagent, or Diagnostic Aid 34620-78-5 ((D-glucose)-isomer) T128073 maltoheptaose T128072 maltoheptose T349118 maltoheptaose, (D-glucose)-isomer 1999 08 18 C001755 methyl-4,5-benzindan-2-carboxylate 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *INDENES (72-75) CARBOXYLIC ACIDS (72-76) *D007189 Indans J Biol Chem 247(10):3029;1972 NLM NLM M0042073 methyl-4,5-benzindan-2-carboxylate C0601185 1H-Benz(e)indene-2-carboxylic acid, 2,3-dihydro-, methyl ester 78150-03-5 T072076 methyl-4,5-benzindan-2-carboxylate C031154 ribose 1-phosphate 1981 08 21 2000 12 22 1998 1999 2000 2001 2001A 2002 RN given refers to (D)-isomer 36 *D012267 Ribosemonophosphates Anal Biochem 1981;112(1):151 RLS WXM WXM M0098088 ribose 1-phosphate C0073257 14075-00-4 T118 Carbohydrate T123 Biologically Active Substance 18646-11-2 ((alpha-D)-isomer) 21317-51-1 ((beta-D)-isomer) M0098088 M0319133 M0098088 M0319134 T128092 ribose 1-phosphate M0319133 ribose 1-phosphate, (alpha-D)-isomer C0102522 18646-11-2 T118 Carbohydrate T123 Biologically Active Substance M0098088 M0319133 T349133 ribose 1-phosphate, (alpha-D)-isomer 1999 08 18 T128091 alpha-D-ribofuranose 1-phosphate M0319134 ribose 1-phosphate, (beta-D)-isomer C0955110 21317-51-1 T118 Carbohydrate T123 Biologically Active Substance M0098088 M0319134 T349134 ribose 1-phosphate, (beta-D)-isomer 1999 08 18 C087984 scalloped protein 1994 07 25 2001 02 08 1996 1997 1998 1999 2000 2001 2001A 2002 has been sequenced 15 *D014157 Transcription Factors D007301 Insect Hormones Science 1994 Jul 1;265(5168):109-14 THA WXM WXM M0232930 scalloped protein C0256280 0 T262935 scalloped protein T262934 scalloped gene product C062392 STE12 protein 1990 02 15 2001 10 31 1998 1999 2000 2001 2001A 2001B 2002 from Saccharomyces cerevisiae ; Cryptococcus neoformans; involved in cell-type-specific transcription ; signal transduction; part of protein-DNA complexes; amino acid sequence given in first source 69 *D005656 Fungal Proteins *D014157 Transcription Factors Genes Dev 1989;3(9):1349 RLS BMB BMB M0172723 STE12 protein C0075195 0 T202728 STE12 protein T202727 STE gene product C001768 aldol-histidine 1972 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 trifunctional collagen crosslink; structure 0 *HISTIDINE (72-75) D006639 Histidine *Q000031 analogs ; derivatives NLM VSR NLM M0042090 aldol-histidine C0601187 2,10-diamino-5-hydroxymethyl-6-(N-1-histidyl) undecandioic acid 38964-85-1 T072093 aldol-histidine C087992 avenacosidase 1994 07 26 2001 02 08 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a 60-kDa protein that copurifies with phytochrome; a part of the defense system of Avena sativa; amino acid sequence given in first source; GenBank X78433 2 *D001617 beta-Glucosidase FEBS Lett 1994 Jun 20;347(1):51-4 PML WXM WXM M0232951 avenacosidase C0256295 EC 3.2.1.- T262956 avenacosidase T262955 p60 protein, Avena C001773 1,3,2-dioxaphosphorinane-2-oxide 1972 01 01 1982 02 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 *PHOSPHORANES (72-76) CYCLIC P-OXIDES (72-82) *D009943 Organophosphorus Compounds Biochem J 155(3):717;1976 NLM NBM NLM M0042100 1,3,2-dioxaphosphorinane-2-oxide C0043881 1,3,2-Dioxaphosphorinane, 2-oxide 16352-21-9 T072103 1,3,2-dioxaphosphorinane-2-oxide C031193 angiotensin II, Asp(1)-Val(5)- 1981 08 27 2000 12 22 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to (L-Asp-L-Val)-isomer 20 D000804 Angiotensin II *Q000031 analogs ; derivatives Clin Sci 1981;61(1):111 RLS WXM WXM M0098211 angiotensin II, Asp(1)-Val(5)- C0051859 53-75-8 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance 63-16-1 ((D-Asp-L-Val)-isomer) 63-17-2 ((D-beta-Asp-L-Val)-isomer) M0098211 M0319141 M0098211 M0319142 T128215 angiotensin II, Asp(1)-Val(5)- T128210 1-Asp-5-Val-angiotensin II T128211 5-valyl angiotensin II T128212 angiotensin II, aspartyl(1)-valine(5)- T128213 angiotensin, Val(5)- T128214 angiotensin, valyl(5)- M0319141 angiotensin II, Asp(1)-Val(5)-, (D-Asp-L-Val)-isomer C0955111 63-16-1 T116 Amino Acid, Peptide, or Protein M0098211 M0319141 T349141 angiotensin II, Asp(1)-Val(5)-, (D-Asp-L-Val)-isomer 1999 08 18 M0319142 angiotensin II, Asp(1)-Val(5)-, (D-beta-Asp-L-Val)-isomer C0970358 63-17-2 T116 Amino Acid, Peptide, or Protein M0098211 M0319142 T349142 angiotensin II, Asp(1)-Val(5)-, (D-beta-Asp-L-Val)-isomer 1999 08 18 C087996 G11 protein 1994 07 27 2001 02 08 1999 2000 2001 2001A 2002 gene G11 is adjacent to the complement C4A gene in the human major histocompatibility complex; has serine/threonine kinase activity; amino acid sequence in first source 6 *PROTEINS (94-98) *D009687 Nuclear Proteins Hum Mol Genet 1994 Mar;3(3):481-8 BMB WXM WXM M0232959 G11 protein C0256301 0 T262964 G11 protein T262963 G11 gene product C001783 3 beta,15 alpha-dihydroxy-5-pregnen-20-one 1972 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D006907 Hydroxypregnenolone D007536 Isomerism Steroids 20(2):129;1972 NLM VSR NLM M0042109 3 beta,15 alpha-dihydroxy-5-pregnen-20-one C0601191 0 T072112 3 beta,15 alpha-dihydroxy-5-pregnen-20-one C001788 meglumine iozomate 1972 01 01 1997 05 28 1997 1998 1999 2000 2001 2002 structure 0 *DIATRIZOATE (72-75) DIATRIZOATE/*analogs (75-79) MEGLUMINE/*analogs (75-79) SORBITOL (72-77) *D003974 Diatrizoate Meglumine Acta Radiol 17(4):433;1976 Upsala J Med Sci 77(1):19;1972 NLM TBT NLM M0042123 meglumine iozomate C0065889 1-deoxy-1-(methylamino)-D-glucitol, 3,3'-(1,4-butanediylbis(oxy(2-hydroxy-3,1-propanediyl)(acetylimino)))bis(5-(acetylmethylamino)-2,4,6-triiodobenzoate) (2:1) (salt) 30804-68-3 M0042123 M0042122 M0042123 M0042121 T072126 meglumine iozomate M0042122 dimer Bjoerk C0114051 M0042123 M0042122 T072125 dimer Bjoerk M0042121 Ph DZ 59B C0136398 M0042123 M0042121 T072124 Ph DZ 59B C001793 N-t-butylnorchlorcyclizine 1972 01 01 1994 06 27 1995 1996 1997 1998 1999 2000 2001 2002 0 *CHLORCYCLIZINE (74-75) *PIPERAZINES (72-74) CHLORCYCLIZINE/*analogs (76-94) *D010879 Piperazines J Pharmacol Exp Therapeut 182(3):507;1972 NLM BVL TPW M0042136 N-t-butylnorchlorcyclizine C0068303 24342-57-2 T072139 N-t-butylnorchlorcyclizine C001797 inferron 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D007501 Iron Laryngol Rhinol Otol (Stuttg) 51(7):438;1972 NLM NLM M0042138 inferron C0601194 0 T072141 inferron C001810 Eutergine 1972 01 01 1997 08 14 1998 1999 2000 2001 2002 contains dihydroergotoxine; sparteine and papaverine 1 *ERGOT ALKALOIDS, HYDROGENATED (72-75) *D004088 Dihydroergotoxine *D010208 Papaverine *D013034 Sparteine D004338 Drug Combinations D002561 Cerebrovascular Disorders Q000188 drug therapy Lille Med 17(5):819;1972 NLM MLH TPW M0042165 Eutergine C0059911 0 T072168 Eutergine C001814 UK 4462 1973 01 01 1982 10 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *SULFONES (73-82) *D000578 Amidines Xenobiotica 2(2):179;1972 NLM VSR NLM M0042166 UK 4462 C0601200 N-(3-chlorobenzenesulfonyl)acetamidine 30289-21-5 T072169 UK 4462 C001820 3-acetoxy-1-acetyl-5-methylpyrazole 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 acetylating agent for proteins 0 *D011720 Pyrazoles J Biochem (Tokyo) 72(1):65;1972 NLM VSR NLM M0042190 3-acetoxy-1-acetyl-5-methylpyrazole C0601201 38004-22-7 T072193 3-acetoxy-1-acetyl-5-methylpyrazole C001823 2-aminoethylphosphonolipid 1973 01 01 1980 10 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 ETHYLAMINES (73-81) *D010743 Phospholipids Biochim Biophys Acta 282(1):93-104;1972 NLM NBM NLM M0042191 2-aminoethylphosphonolipid C0045882 0 T072194 2-aminoethylphosphonolipid C001855 P-890 1973 01 01 2001 09 05 2002 0 *D002734 Chlorophyll NLM TWD sjn M0042241 P-890 C0069903 0 T072244 P-890 Pharm Chem Syn, p. 476 T072243 P 890 C001830 tryptones 1973 01 01 1989 08 08 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 25 TRYPSIN (73-75) TRYPSIN/analogs (75-82) *D010461 Peptones Arch Exp Veterinaermed 26(1):30;1972 NLM PLS RLS M0042200 tryptones C0077437 73049-73-7 T072203 tryptones C023777 L 628914 1978 01 01 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 BENZYL COMPOUNDS (78-82) D000225 Adenine *Q000031 analogs ; derivatives Poultry Sci 56(6):2039;1977 Poultry Sci 57(2):381;1978 NLM CCR CCR M0081407 L 628914 C0064473 6-amino-9-(2,6-dichlorobenzyl)purine 38042-11-4 T111410 L 628914 T111408 L 628,914 T111409 L-628,914 C001859 ruticulomycin 1973 01 01 2000 08 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 0 *D000900 Antibiotics Biochim Biophys Acta 277(2):269;1972 NLM SXD SXD M0042242 ruticulomycin C0601220 12798-37-7 T072245 ruticulomycin C001847 bensulide 1973 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *SULFONAMIDES (73-82) *D009946 Organothiophosphorus Compounds J Agr Food Chem 20(3):656;1972 NLM VSR NLM M0042227 bensulide C0601209 O,O-diisopropyl phosphorothioate S-ester with N-(2-mercaptoethyl)benzenesulfonamide 741-58-2 T072230 bensulide C062393 Abd-B proteins 1990 02 15 2001 01 26 1995 1996 1997 1998 1999 2000 2001 2001A 2002 isolated two proteins MW 54 ; 36 kDa; from bithorax complex of Drosophila; amino acid sequence given in first source 60 *INSECT HORMONES (90-95) *D018398 Homeodomain Proteins Genes Dev 1989;3(9):1424 RLS WXM WXM M0172725 Abd-B proteins C0050358 0 T202730 Abd-B proteins T202729 Abdominal-B proteins C030755 adenine-N-oxide 1981 08 04 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 5 D000225 Adenine *Q000031 analogs ; derivatives J Parasitol 1981;67(2):137 MEG CCR CCR M0097066 adenine-N-oxide C0050740 700-02-7 T127070 adenine-N-oxide T127068 adenine-1-N-oxide T127069 adenine-1-oxide C001861 humin 1973 01 01 1984 01 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 humic acid according to Dorland; Environ Letters 3(1):1-12;1972 says it is a higher MW material, insoluble in both acid ; alkali (humic acid is soluble in alkali) 10 HUMIC ACID (73-75) *D006812 Humic Acids D012987 Soil NLM MEG NLM M0042243 humin C0063027 0 T072246 humin C411644 trizol 2000 08 07 2000 2001 2002 a monophasic solution of phenol and guanidine isothiocyanate 2 *D006146 Guanidines *D010636 Phenols D012996 Solutions J Virol Methods 2000 Jan;87(1-2):29-39 SXK SXK M0367360 trizol C0916178 0 T109 Organic Chemical T421006 trizol 2000 08 07 C035618 9-(indole-3-propyl)-1-methyladeninium 1982 09 24 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 D000225 Adenine *Q000031 analogs ; derivatives Biochem Biophys Res Commun 1982;107(2):746 VSR CCR CCR M0109043 9-(indole-3-propyl)-1-methyladeninium C0616887 0 M0109043 M0109041 T139047 9-(indole-3-propyl)-1-methyladeninium T139046 9-IPMA M0109041 9-(indole-3-propyl)-1-methyladeninium iodide C0616885 M0109043 M0109041 T139045 9-(indole-3-propyl)-1-methyladeninium iodide C086239 N-((1,2,3,6-tetrahydro-4-pyridyl)methyl)-2-hydroxy-2,2-diphenylacetamide 1994 04 12 2000 08 07 1997 1998 1999 2000 2000A 2001 2002 inhibits bladder contraction; structure given in first source 1 *D000081 Acetamides *D010880 Piperidines Chem Pharm Bull (Tokyo) 1994 Jan;42(1):74-84 PML TWD TWD M0228635 N-((1,2,3,6-tetrahydro-4-pyridyl)methyl)-2-hydroxy-2,2-diphenylacetamide C0252660 0 T109 Organic Chemical T121 Pharmacologic Substance T258640 N-((1,2,3,6-tetrahydro-4-pyridyl)methyl)-2-hydroxy-2,2-diphenylacetamide T258639 TPM-HDPA C002174 methyl-ethyl-monohydro-lumiflavin 1973 01 01 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2001B 2002 0 *D005415 Flavins Eur J Biochem 25(3):573;1972 NLM TWD TWD M0042666 methyl-ethyl-monohydro-lumiflavin C0601342 Benzo(g)pteridinyl, 5-ethyl-2,3,4,5,10,-hexahydro-3,7,8,10-tetramethyl-2,4-dioxo- 35835-01-9 T072669 methyl-ethyl-monohydro-lumiflavin T072668 Benzo(g)pteridin-5-iumyl, 5-ethyl-2,3,5,10-tetrahydro-4-hydroxy-3,7,8,10-tetramethyl-2-oxo-, hydroxide, inner salt C001868 n-butylthioadenosine 1973 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ADENOSINE (73-75) SULFIDES (75-76) *D013872 Thionucleosides D000241 Adenosine *Q000031 analogs ; derivatives Eur J Pharmacol 19(2):246;1972 NLM NLM M0042256 n-butylthioadenosine C0601226 36965-96-5 T072259 n-butylthioadenosine C062782 protein acyltransferase 1990 03 06 2001 01 26 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 human placental enzyme active in posttranslational acylation of membrane glycoproteins 5 *D000123 Acetyltransferases Biochem Soc Trans 1989;17(5):859 TPW WXM WXM M0173618 protein acyltransferase C0639839 EC 2.3.1.- T203623 protein acyltransferase T203622 glycoprotein palmitoyltransferase C062845 placental protein 19 1990 03 09 2001 01 26 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 has alpha1-beta1 electrophoretic mobility; MW 36.5 kDa 3 *D011257 Pregnancy Proteins Histochemistry 1989;93(2):167 RLS WXM WXM M0173741 placental protein 19 C0071193 0 T203746 placental protein 19 T203745 PP19 C001878 mammeisin 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ALKENES (73-76) *D003374 Coumarins J Pharm Sci 61(10):1603;1972 NLM NLM M0042270 mammeisin C0601233 5,7-dihydroxy-8-(3-methyl-2-butenyl)-6-(3- methyl-1-oxobutyl)-4-phenyl-2H-1-benzopyran-2-one 18483-64-2 T072273 mammeisin C001879 3,4-dimethoxyphenylacetamide 1973 01 01 1982 10 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CATECHOLS (73-82) METHYL ETHERS (73-74) *D000081 Acetamides J Pharm Sci 61(10):1611;1972 NLM VSR NLM M0042271 3,4-dimethoxyphenylacetamide C0601234 5663-56-9 T072274 3,4-dimethoxyphenylacetamide C001880 peuarenine 1973 01 01 1982 09 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 PYRANS (73-82) VALERATES (73-76) *D003374 Coumarins J Pharm Sci 16(10):1643;1972 NLM VSR NLM M0042272 peuarenine C0601235 37975-61-4 T072275 peuarenine C001881 xanthalin 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 PYRANS (73-75) VALERATES (73-76) *D003374 Coumarins J Pharm Sci 16(10):1643;1972 NLM NLM M0042273 xanthalin C0601236 21800-48-6 T072276 xanthalin C002175 progesterone 17 alpha-hydroperoxide 1973 01 01 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 5 *PROGESTERONE (73-75) PEROXIDES (73-76) D011374 Progesterone *Q000031 analogs ; derivatives Arch Biochem Biophys 153(2):495;1972 Biochim Biophys Res Commun 65(4):1320;1975 Hormone Res 6(4):213;1975 NLM TWD TWD M0042668 progesterone 17 alpha-hydroperoxide C0072085 28990-01-4 T072671 progesterone 17 alpha-hydroperoxide T072670 17alpha-hydroperoxyprogesterone C001883 stichoposide 1973 01 01 1991 03 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 triterpene glycoside; RN given refers to stichoposide A 24 *TOXINS (73-76) ECHINODERMATA (73-76) GLYCOSIDES (74-81) *D006027 Glycosides *D014315 Triterpenes D006697 Holothurin D012616 Sea Cucumbers D014118 Toxins Comp Biochem Physiol 52(2):321;1975 Prikl Biokhim Mikrobiol 14(4):583;1978 Toxicon 10(3):299;1972 NLM LBG NLM M0042280 stichoposide C0075249 37341-37-0 D011838 Radiation-Sensitizing Agents 11104-37-3 (stichoposide A1) 37341-38-1 (stichoposide C) M0042280 M0042276 M0042280 M0042277 M0042280 M0042275 M0042280 M0307802 M0042280 M0307801 M0042280 M0042279 M0042280 M0042278 T072283 stichoposide M0042276 holotoxin B1 C0122207 M0042280 M0042276 T072279 holotoxin B1 M0042277 holotoxins C0122208 M0042280 M0042277 T072280 holotoxins M0042275 holotoxin A1 C0122206 M0042280 M0042275 T072278 holotoxin A1 M0307802 stichoposide C of stichoposide C0894130 37341-38-1 M0042280 M0307802 T337802 stichoposide C of stichoposide 1999 08 18 M0307801 stichoposide A1 of stichoposide C0894129 11104-37-3 M0042280 M0307801 T337801 stichoposide A1 of stichoposide 1999 08 18 M0042279 stichoposide A1 C0143677 M0042280 M0042279 T072282 stichoposide A1 M0042278 stichoposide A C0143676 M0042280 M0042278 T072281 stichoposide A C001884 prymnesin 1973 01 01 1982 08 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 MASTICOPHORA (73-76) *D008074 Lipoproteins D014118 Toxins J Membr Biol 16(3):237;1974 Naunyn Schmiedebergs Arch Pharmacol 287:349;1975 Toxicon 10(3):286;1972 NLM ESH NLM M0042281 prymnesin C0072517 11025-94-8 T072284 prymnesin C037636 9-furfuryladenine 1983 04 15 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 D000225 Adenine *Q000031 analogs ; derivatives Adv Prostaglandin Thromboxane Leukotriene Res 1983;12:7 MEG CCR CCR M0113714 9-furfuryladenine C0618373 2296-08-4 M0113714 M0113712 T143718 9-furfuryladenine M0113712 SQ 4647 C0618372 M0113714 M0113712 T143716 SQ 4647 T143717 SQ-4647 C001891 androcymbine 1973 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 *DIBENZOCYLOHETENES (73-82) *D000470 Alkaloids J Chem Soc (Org) 14(0):1736;1972 NLM VSR NLM M0042292 androcymbine C0162908 2115-98-2 T072295 androcymbine C062863 RhaR protein 1990 03 12 2001 01 26 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; positive regulator of the L-rhamnose operons in E coli 4 *D004268 DNA-Binding Proteins J Mol Biol 1990;211(1):75 TPW WXM WXM M0173774 RhaR protein C0245969 0 T203779 RhaR protein T203778 RhaR gene product C001911 clioxanide 1973 01 01 1979 10 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *SALICYLAMIDES (73-77) ANILINE CPDS (73-76) *D012458 Salicylanilides Aust Vet J 51(11):500;1975 Vet Rec 90(19):523;1972 Xenobiotica 1979;9(4):263 NLM RLS NLM M0042316 clioxanide C0055885 4'-chloro-3,5-diiodosalicylanilide acetate 14437-41-3 T072319 clioxanide Merck Index, 9th ed, p. 303, #2326 C001922 lumiflavin 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 38 *D005415 Flavins J Am Chem Soc 98(13):3955;1976 J Supramol Struct 2(5-6):751;1974 Photochem Photobiol 22(1-2):7;1975 NLM NLM M0042327 lumiflavin C0065242 1088-56-8 T072330 lumiflavin Dorland p.853 C001925 Cimporhin 1973 01 01 1982 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 tramazoline + chlorpheniramine + AP 67 0 *D002744 Chlorpheniramine *D007093 Imidazoles *D010078 Oxazines D004338 Drug Combinations Med Monatschr 26(6):286;1972 NLM NBM NLM M0042330 Cimporhin C0055733 8069-46-3 T072333 Cimporhin C001936 gatratet 1973 01 01 1993 02 12 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D009842 Oligopeptides Am Surgeon 38(10):569;1972 NLM BXB NLM M0042349 gatratet C0601250 L-Phenylalaninamide, N-((phenylmethoxy)carbonyl)-L-tryptophyl-L-methionyl-L-alpha-aspartyl- 2283-80-9 M0042349 M0042348 M0042349 M0042347 T072352 gatratet M0042348 carbobenzoxy-Trp-Met-Asp-Phe-amide C0601249 M0042349 M0042348 T072351 carbobenzoxy-Trp-Met-Asp-Phe-amide M0042347 carbobenzoxy-L-tryptophyl-L-methionyl-L-aspartyl-L-phenylalanine amide C0601248 M0042349 M0042347 T072350 carbobenzoxy-L-tryptophyl-L-methionyl-L-aspartyl-L-phenylalanine amide C114847 RFT5-SMPT-dgA immunotoxin 1998 10 19 2000 07 24 1998 1999 2000 2000A 2001 2002 RFT5 monoclonal antibody linked via the disulfide linker SMPT to the deglycosylated ricin A chain; used in treating Hodgkin's lymphoma 1 *D000911 Antibodies, Monoclonal *D012276 Ricin Leukemia Lymphoma 1998 Aug;30(5-6):525-37 THA SXD SXD M0295989 RFT5-SMPT-dgA immunotoxin C0758270 0 T325994 RFT5-SMPT-dgA immunotoxin C001939 N-acetyldaunomycin 1973 01 01 2000 07 31 2001 2002 RN given refers to (8S-cis)- isomer 6 *DAUNOMYCIN (73-75) D003630 Daunorubicin *Q000031 analogs ; derivatives Biochem Med 6(5):445;1972 Cancer Res 1980;40(4):1077 NLM CCR sjn M0042351 N-acetyldaunomycin C0067693 32385-10-7 T109 Organic Chemical T195 Antibiotic 33644-62-1 (HCl(8S-cis)-isomer) M0042351 M0307824 T072354 N-acetyldaunomycin T072353 N-acetyldaunorubicin M0307824 N-acetyldaunomycin, hydrochloride, (8S-cis)-isomer C0894140 33644-62-1 T109 Organic Chemical T195 Antibiotic M0042351 M0307824 T337824 N-acetyldaunomycin, hydrochloride, (8S-cis)-isomer 1999 08 18 C001947 xanthocillin Y 1 1973 01 01 1982 04 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 NITRILES (73-82) PHENOLS (73-75) *D002070 Butadienes Chem Ber 105(9):3061;1972 NLM RLS NLM M0042358 xanthocillin Y 1 C0601252 38965-69-4 T072361 xanthocillin Y 1 C001988 ENT-60210 1973 01 01 2001 01 26 1996 1997 1998 1999 2000 2001 2001A 2002 0 DIMETHYLAMINES (73-82) *D009943 Organophosphorus Compounds J Econ Entomol 64:1027;1971 NLM TWD TWD M0042426 ENT-60210 C0601267 N-(2-methoxyethyl)-N',N',N'',N''-tetramethylphosphoric triamide 7326-30-9 T072429 ENT-60210 T072428 ENT 60210 C001961 MJ-8592-1 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 IMINES (73-76) *D007211 Indoles Res Commun Chem Pathol Pharmacol 4(2):467;1972 NLM NLM M0042376 MJ-8592-1 C0066629 1-((tert-butylimino)methyl)-2-(3-indolyl)indoline 36815-43-7 T072379 MJ-8592-1 C001965 N,N'-hexamethylenebis(1-aziridinecarboxamide) 1973 01 01 1995 12 12 1996 1997 1998 1999 2000 2001 2002 0 *AZIRIDINES (75-76) *AZIRINES (73-75) CARBOXYLIC ACIDS (73-75) D014508 Urea *Q000031 analogs ; derivatives J Econ Entomol 65(5):1353;1972 NLM MLH NLM M0042382 N,N'-hexamethylenebis(1-aziridinecarboxamide) C0067312 2271-93-4 T072385 N,N'-hexamethylenebis(1-aziridinecarboxamide) C066700 regA protein, bacteriophage T4 1991 01 31 2001 01 26 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence has been determined; do not confuse with Pseudomonas aeruginosa exotoxin A (regA protein) 11 *D014764 Viral Proteins D017122 Bacteriophage T4 Nucleic Acids Res 1990;18(23):7083 TPW WXM WXM M0183019 regA protein, bacteriophage T4 C0084307 0 T213024 regA protein, bacteriophage T4 T213023 bacteriophage T4 regA protein C066710 wetA protein 1991 02 01 2001 01 26 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; activates spore-specific gene expression 3 *D005656 Fungal Proteins D001233 Aspergillus nidulans Mol Cell Biol 1991;11(1):55 TPW WXM WXM M0183045 wetA protein C0085002 133424-15-4 T213050 wetA protein T213049 wetA gene product C001970 allolactose 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 5 *D007785 Lactose Can J Biochem 53(9):1035;1975 J Mol Biol 115(2):195;1977 J Molec Biol 69(3):397;1972 NLM NLM M0042396 allolactose C0051211 645-03-4 T072399 allolactose C018196 adenosine 5'-carboxamide 1979 01 01 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 1 AMIDES (79-81) D000241 Adenosine *Q000031 analogs ; derivatives Biochem Pharmacol 27(18):2197;1978 Naunyn Schmiedeberg's Arch Pharmacol 287 suppl:35;1975 NLM CCR CCR M0069496 adenosine 5'-carboxamide C0050751 beta-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy- 35788-21-7 T099499 adenosine 5'-carboxamide T099498 adenosine 5'-carboxylic acid amide T099497 ADN 5'-CXAAM C115945 rhododendrol 1998 12 15 2000 07 24 1999 2000 2000A 2001 2002 structure in first source 1 *D000440 Butanols D009569 Nitric Oxide Q000037 antagonists ; inhibitors Planta Med 1998 Oct;64(7):598-602 SZM SXD SXD M0298328 rhododendrol C0760585 0 T328333 rhododendrol C001982 erythro-alpha-ethyl-alpha'-methyl-4,4'-dihydroxybibenzyl 1973 01 01 1991 06 03 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CONTRACEPTIVES, POSTCOITAL (73-76) PHENOLS (73-76) *D001632 Bibenzyls Brit Med Bull 26(1):48;1970 NLM LBG NLM M0042411 erythro-alpha-ethyl-alpha'-methyl-4,4'-dihydroxybibenzyl C0601260 20576-52-7 T072414 erythro-alpha-ethyl-alpha'-methyl-4,4'-dihydroxybibenzyl C066720 HtpG protein 1991 02 05 2001 01 26 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source 22 *HEAT-SHOCK PROTEINS (91-96) *D018841 Heat-Shock Proteins 90 D001426 Bacterial Proteins D004926 Escherichia coli D014734 Vibrio cholerae Proc Natl Acad Sci USA 1990;87(24):9898 TPW WXM WXM M0183071 HtpG protein C0082938 134548-76-8 T213076 HtpG protein T213075 heat-shock protein HtpG C115883 RH4 peptide 1998 12 11 2000 07 24 1999 2000 2000A 2000B 2001 2002 designed peptide capable of forming alpha-helical coiled coils; amino acid sequence in first source 1 *D011506 Proteins Science 1998 Nov 20;282(5393):1462-7 THA SXD SXD M0298190 RH4 peptide C0760447 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T328195 RH4 peptide C066753 self-incompatibility associated protein S2, Solanum chacoense 1991 02 12 2001 01 26 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; pistil-specific protein of 30 kDa 1 *D010940 Plant Proteins Mol Gen Genet 1990;224(3):341 TPW WXM WXM M0183154 self-incompatibility associated protein S2, Solanum chacoense C0643698 135374-34-4 T213159 self-incompatibility associated protein S2, Solanum chacoense T213158 S(2) protein, Solanum chacoense C066754 self incompatibility associated protein S3, Solanum chacoense 1991 02 12 2001 01 26 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; pistil-specific protein of 30 kDa 2 *D010940 Plant Proteins Mol Gen Genet 1990;224(3):341 TPW WXM WXM M0183156 self incompatibility associated protein S3, Solanum chacoense C0643700 135374-33-3 T213161 self incompatibility associated protein S3, Solanum chacoense T213160 S(3) protein, Solanum chacoense C001994 N,N-diethyl-2,5-dinitropyrrole-1-acetamide 1973 01 01 1982 09 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ACETAMIDES (73-82) NITRO COMPOUNDS (73-76) *D011758 Pyrroles D013091 Spermatogenesis Q000187 drug effects WHO Rpts 424:9; NLM VSR NLM M0042439 N,N-diethyl-2,5-dinitropyrrole-1-acetamide C0601274 1H-Pyrrole-1-acetamide, N,N-diethyl-2,5-dinitro- 78232-31-2 T072442 N,N-diethyl-2,5-dinitropyrrole-1-acetamide C001999 phenylcyclohexylglycolloylcholine 1973 01 01 1982 09 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN in Chemline for (S)-isomer; RN for (R)-isomer: 37746-95-5 0 *CHOLINE (73-75) CYCLOHEXANES (73-76) MANDELIC ACIDS (73-75) D002794 Choline *Q000031 analogs ; derivatives J Pharm Pharmacol 24(10):753;1972 NLM VSR NLM M0042448 phenylcyclohexylglycolloylcholine C0601275 37746-96-6 T072451 phenylcyclohexylglycolloylcholine C002001 allocholic acid 1975 01 01 1983 07 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 see also records for ursocholic and cholic acids 3 *D002793 Cholic Acids Eur J Biochem 66(3):507;1976 Vrach Delo 5:77;1976 NLM DLJ NLM M0042451 allocholic acid C0051205 3 alpha,7 alpha,12 alpha-trihydroxy-5 alpha-cholan-24-oic acid 2464-18-8 T072454 allocholic acid C002202 4-oxoretinoic acid 1973 01 01 2000 07 31 2001 2002 RN given refers to cpd without isomeric designation; structure 60 *CAROTENOIDS (73-75) FATTY ACIDS, UNSATURATED (74-75) D014212 Tretinoin *Q000031 analogs ; derivatives Arch Biochem Biophys 1980;199(2):374 Biochemistry 18(10):2092;1979 Drug Metab Dispos 1982;10(3):284 Int J Vitam Nutr Res 42(3):368;1972 NLM CCR sjn M0042706 4-oxoretinoic acid C0048667 38030-57-8 T109 Organic Chemical 71748-58-8 ((13-cis)-isomer) M0042706 M0307888 M0042706 M0042704 M0042706 M0042705 T072709 4-oxoretinoic acid T072704 4-ketoretinoic acid M0307888 4-oxoretinoic acid, (13-cis)-isomer C0097444 71748-58-8 T109 Organic Chemical M0042706 M0307888 T337888 4-oxoretinoic acid, (13-cis)-isomer 1999 08 18 T072705 4-oxo-13-cis-retinoic acid T072706 4-oxo-isotretinoin M0042704 4-oxo-trans-retinoic acid C0097448 T109 Organic Chemical M0042706 M0042704 T072707 4-oxo-trans-retinoic acid M0042705 Ro 12-4824 C0140739 T109 Organic Chemical M0042706 M0042705 T072708 Ro 12-4824 C002009 piperidinoisopropylcarbanilate 1973 01 01 1982 10 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PIPERIDINES (73-82) *D002219 Carbamates Cesk Farm 21(7):315;1972 NLM VSR NLM M0042462 piperidinoisopropylcarbanilate C0601279 0 T072465 piperidinoisopropylcarbanilate C002094 flavodic acid 1972 01 01 2001 08 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 capillary protective agent; RN given refers to parent cpd; structure 2 *BENZOPYRANS (72-75) ETHERS (74-76) *D005419 Flavones Clin Ter 58(1):47;1971 Minerva Chir 30(19):989;1975 Minerva Otorinolaringol 21(5):196;1971 NLM CCR CCR M0042568 flavodic acid C0060435 37470-13-6 13358-62-8 (di-Na salt) M0042568 M0042565 M0042568 M0307863 M0042568 M0042566 M0042568 M0042567 T072571 flavodic acid T072566 2-phenyl-5,7-dioxyacetate-benzo- gamma-pyrone T072567 2-phenyl-gamma-benzopyrone-5,7-dioxyacetate M0042565 benzogammapirone C0105644 M0042568 M0042565 T072568 benzogammapirone M0307863 flavodic acid, disodium salt C0951094 13358-62-8 M0042568 M0307863 T337863 flavodic acid, disodium salt 1999 08 18 M0042566 flavodic acid sodium salt C0117829 M0042568 M0042566 T072569 flavodic acid sodium salt M0042567 Pericel C0136116 M0042568 M0042567 T072570 Pericel C002018 chalcomycin 1973 01 01 1989 08 01 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 5 LACTONES (73-89) *D015548 Antibiotics, Macrolide NLM RJM RLS M0042475 chalcomycin C0055250 20283-48-1 T072478 chalcomycin Merck Index, 9th ed, p.255 C002019 triphenyllead acetate 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ACETIC ACIDS (73-74) BENZENE DERIVATIVES (73-76) *D009942 Organometallic Compounds D007854 Lead Biochem J 127(2):24P;1972 Toxicol Appl Pharmacol 46(3):567;1978 NLM NLM M0042476 triphenyllead acetate C0077253 (acetyloxy)triphenylplumbane 1162-06-7 T072479 triphenyllead acetate C002025 22-trans-24-norcholesta-5,22-diene-3 beta-ol 1974 01 01 1982 07 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 sterol from clam 0 NORSTEROIDS (74-82) *D002775 Cholestadienols Comp Biochem Physiol (B) 41(1):121;1972 NLM VSR NLM M0042480 22-trans-24-norcholesta-5,22-diene-3 beta-ol C0046657 0 T072483 22-trans-24-norcholesta-5,22-diene-3 beta-ol C002027 estradiol enanthate 1973 01 01 1991 06 03 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 a parenteral female contraceptive 12 CAPRYLATES (73-75) HEPTANOATES (75-76) D004958 Estradiol *Q000031 analogs ; derivatives Contraception 1(1):195;1970 NLM LBG NLM M0042483 estradiol enanthate C0059619 4956-37-0 T072486 estradiol enanthate Merck Index, 9th ed, p. 486, in #3626 C002029 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 metabolite of norethynodrel 0 *ESTRANES (73-75) ALKYNES (73-75) D009641 Norethynodrel *Q000031 analogs ; derivatives Xenobiotica 2(3):253;1972 NLM VSR NLM M0042484 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol C0601281 19-Norpregn-5(10)-en-20-yne-3,17-diol, (3alpha,17alpha)- 21466-08-0 T072487 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol C002107 propiram 1973 01 01 2000 07 31 2001 2002 RN given refers to parent cpd; synonym Bay 4503 refers to fumarate[1:1]; practically always used as fumarate in medicine; structure 9 *PROPIONATES (73-82) PIPERIDINES (73-76) *D011725 Pyridines J Clin Pharmacol 12(11):440;1972 J Clin Pharmacol 16(11-12):611;1976 NLM CCR sjn M0042579 propiram C0072205 15686-91-6 T109 Organic Chemical T121 Pharmacologic Substance 13717-04-9 (fumarate[1:1]) 52373-68-9 (fumarate[1:1](DL)-isomer) M0042579 M0042576 M0042579 M0307866 M0042579 M0307867 T072582 propiram Negwer, 5th ed, #3210 USAN 1980, p.270 - fumarate T072580 N-(1-methyl-2-piperidinoethyl)-N-(2-pyridyl)propionamide M0042576 Bay 4503 C0105281 T109 Organic Chemical T121 Pharmacologic Substance M0042579 M0042576 T072579 Bay 4503 M0307866 propiram fumarate (1:1) C0138663 13717-04-9 T109 Organic Chemical T121 Pharmacologic Substance M0042579 M0307866 T337866 propiram fumarate (1:1) 1999 08 18 T072581 propiram fumarate M0307867 propiram fumarate (1:1), (DL)-isomer C0894167 52373-68-9 T109 Organic Chemical T121 Pharmacologic Substance M0042579 M0307867 T337867 propiram fumarate (1:1), (DL)-isomer 1999 08 18 C002045 hydroxycyprazine 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *HERBICIDES (73-75) CYCLOPROPANES (75-76) PROPYLAMINES (73-76) *D014227 Triazines J Agr Food Chem 20(6):1286;1972 NLM NLM M0042503 hydroxycyprazine C0601286 2-hydroxy-4-cyclopropylamino-6-isopropylamino-s- triazine 39095-16-4 T072506 hydroxycyprazine C002073 taurinophenetidine 1973 01 01 2001 01 26 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 *ANILINE COMPOUNDS (73-75) *TAURINE (73-75) ETHYL ETHER (73-75) D010628 Phenetidine *Q000031 analogs ; derivatives D013654 Taurine *Q000031 analogs ; derivatives J Pharm Sci 61(11):1791;1972 NLM TWD TWD M0042541 taurinophenetidine C0601296 22103-30-6 T072544 taurinophenetidine T072543 aminoethanesulfonylphenetidine C002047 bis(chloromethyl) sulfone 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 affects rumen fermentation 0 *D013450 Sulfones J Agr Food Chem 20(6):1252;1972 NLM NLM M0042506 bis(chloromethyl) sulfone C0601287 37557-97-4 T072509 bis(chloromethyl) sulfone C068352 MIP1 DNA polymerase 1991 05 17 2001 01 26 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from Saccharomyces cerevisiae; has structural similarity with the E coli DNA polymerase I-type enzymes 4 *D004256 DNA Polymerase I Nucleic Acids Res 1991;19(4):955 RLS WXM WXM M0186973 MIP1 DNA polymerase C0378822 EC 2.7.7.- T216978 MIP1 DNA polymerase T216977 MIP1 gene product C002053 tetritol 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *SUGAR ALCOHOLS (73-76) *D013780 Tetroses FEBS Lett 23(1):69;1972 NLM NLM M0042517 tetritol C0601293 0 T072520 tetritol C002054 umecyanin 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 copper-containing protein from horseradish root 2 *PLANT PROTEINS (73-76) COPPER (73-76) *D008667 Metalloproteins FEBS Lett 23(1):41;1972 NLM NLM M0042518 umecyanin C0077808 0 T072521 umecyanin C002414 25-azacholesterol 1973 01 01 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 AZA STEROIDS (75-76) CHOLESTEROL (73-75) D002784 Cholesterol *Q000031 analogs ; derivatives Poultry Sci 51(2):449;1972 NLM TWD TWD M0042978 25-azacholesterol C0601447 Chol-5-en-3-ol, 24-(dimethylamino)-, (3beta)- 1973-61-1 T072981 25-azacholesterol T072980 24-(dimethylamino)chol-5-en-3 beta-ol C012451 diisobutylnaphthalenesulfonate 1976 01 01 2001 08 17 1998 1999 2000 2001 2001A 2002 3 *D009282 Naphthalenesulfonates Zentralbl Bakteriol (Orig A) 234(3):393;1976 NLM CCR CCR M0059478 diisobutylnaphthalenesulfonate C0114009 52627-01-7 27213-90-7 (Na salt) 53578-91-9 (Ca salt) M0059478 M0059479 M0059478 M0311861 M0059478 M0311860 T089481 diisobutylnaphthalenesulfonate M0059479 Nekal BX C0068492 M0059478 M0059479 T089482 Nekal BX M0311861 diisobutylnaphthalenesulfonate, calcium salt C0952522 53578-91-9 M0059478 M0311861 T341861 diisobutylnaphthalenesulfonate, calcium salt 1999 08 18 M0311860 diisobutylnaphthalenesulfonate, sodium salt C0952521 27213-90-7 M0059478 M0311860 T341860 diisobutylnaphthalenesulfonate, sodium salt 1999 08 18 C068384 ribosomal protein CL23 1991 05 18 2001 01 26 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 chloroplast gene for the ribosomal protein is functional in tobacco; amino acid sequence given in first source 1 *D012269 Ribosomal Proteins FEBS Lett 1991;281(1-2):64 RLS WXM WXM M0187049 ribosomal protein CL23 C0645324 104981-34-2 T217054 ribosomal protein CL23 T217053 CL23 ribosomal protein C068394 DNA strand transfer protein alpha 1991 05 20 2001 01 26 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from meiotic Saccharomyces cerevisiae promotes homologous pairing of DNA without any nucleotide cofactor in the presence of yeast single-stranded DNA-binding protein; MW 34.8 kDa; amino acid sequence given in first source 2 *D004268 DNA-Binding Proteins *D005656 Fungal Proteins Mol Cell Biol 1991;11(5):2576 RLS WXM WXM M0187070 DNA strand transfer protein alpha C0114641 137750-51-7 T217075 DNA strand transfer protein alpha T217074 STPalpha C068399 PUT3 transcriptional activator 1991 05 20 2001 01 26 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from Saccharomyces cerevisiae; transcriptional activator that binds to DNA sequences in the promoters of the proline utilization genes ; is required for the basal ; induced expression of the enzymes in this pathway; amino acid sequence given in first source 12 *D005656 Fungal Proteins *D015534 Trans-Activators Mol Cell Biol 1991;11(5):2609 RLS WXM WXM M0187085 PUT3 transcriptional activator C0139373 138391-78-3 T217090 PUT3 transcriptional activator T217089 PUT3 protein C002076 pustulan 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 12 PLANT EXTRACTS (73-76) *D011134 Polysaccharides Arch Microbiol 104(2):201;1975 Can J Microbiol 18(10):1543;1972 NLM NLM M0042543 pustulan C0072626 37331-28-5 T072546 pustulan C021013 N(6),N(6)-dimethyladenosine 1980 01 01 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 14 D000241 Adenosine *Q000031 analogs ; derivatives D012315 RNA Caps J Biol Chem 254(18):9085;1979 J Biol Chem 254(18):9090;1979 J Biol Chem 254(18):9094;1979 NLM CCR CCR M0075422 N(6),N(6)-dimethyladenosine C0067194 2620-62-4 T105425 N(6),N(6)-dimethyladenosine T105423 6-(gamma,gamma-dimethylamino)purine riboside T105424 6-dimethylaminopurine riboside C002079 benzyl-6-oxopenicillanate 1973 01 01 1993 08 18 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PENICILLIN (73-75) BENZYL COMPOUNDS (73-76) PENICILLANIC ACIDS (76-93) D010397 Penicillanic Acid *Q000031 analogs ; derivatives J Am Chem Soc 94(23):8253;1972 NLM TPW TPW M0042545 benzyl-6-oxopenicillanate C0601297 39126-59-5 T072548 benzyl-6-oxopenicillanate C002080 22-iso-ecdysone 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D004440 Ecdysone Exp Cell Res 74(2):327;1972 NLM NLM M0042546 22-iso-ecdysone C0601298 2 beta, 3 beta, 14, 22 S, 25-pentahydroxy-5 beta- cholest-7-en-6-one 7703-83-5 T072549 22-iso-ecdysone C002082 cyasterone 1973 01 01 1983 02 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 4 *STEROIDS (73-83) D013265 Stigmasterol *Q000031 analogs ; derivatives D007447 Invertebrate Hormones Exp Cell Res 74(2):327;1972 NLM RLS NLM M0042547 cyasterone C0056676 17086-76-9 T072550 cyasterone C004965 hypericin 1969 01 01 2000 07 24 1996 1997 1998 1999 2000 2000A 2001 2002 structure 247 *BENZOPYRENES (69-79) PHENANTHRENES (69-82) D010569 Perylene *Q000031 analogs ; derivatives D011493 Protein Kinase C Q000037 antagonists ; inhibitors Biochim Biophys Acta 1979;587(1):129 ZFA(Stuttgart) 55(12):776;1979 NLM SZM SZM M0046211 hypericin C0063220 1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro(1,10,9,8-opqra)perylene-7,14-dione 548-04-9 D000928 Antidepressive Agents D000970 Antineoplastic Agents D000998 Antiviral Agents D004791 Enzyme Inhibitors D007166 Immunosuppressive Agents D011838 Radiation-Sensitizing Agents T076214 hypericin Merck Index, 9th ed, p. 647, #4785 Negwer #4697 C001176 Leyk 1971 01 01 2001 08 17 1999 2000 2001 2001A 2002 5 CARBOXYLIC ACIDS (71-75) *D013844 Thiazoles NLM TWD TWD M0041276 Leyk C0064885 1950-36-3 M0041276 M0041273 M0041276 M0041274 T071279 Leyk Negwer #2168 M0041273 Leukogen C0376721 M0041276 M0041273 T071276 Leukogen T071278 leucogen M0041274 ethyl-4-carboxy alpha-phenyl-1,2-thiazolidine acetate C0116846 M0041276 M0041274 T071277 ethyl-4-carboxy alpha-phenyl-1,2-thiazolidine acetate C004483 2-aminothiazole 1969 01 01 2001 08 17 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 7 AMINES (73-76) *D013844 Thiazoles D004265 DNA Helicases Q000037 antagonists ; inhibitors Farm Zh 1979;6:25 NLM TWD TWD M0045561 2-aminothiazole C0045900 96-50-4 57530-25-3 (mononitrate) 63589-20-8 (sulfate[1:1]) M0045561 M0308600 M0045561 M0308601 M0045561 M0045560 T075564 2-aminothiazole DATS 73 Negwer 74 M0308600 2-aminothiazole mononitrate C0951259 57530-25-3 M0045561 M0308600 T338600 2-aminothiazole mononitrate 1999 08 18 M0308601 2-aminothiazole sulfate (1:1) C0971911 63589-20-8 M0045561 M0308601 T338601 2-aminothiazole sulfate (1:1) 1999 08 18 M0045560 T157602 C0752376 M0045561 M0045560 T075563 T157602 C002101 chymostatin 1973 01 01 1997 08 14 1998 1999 2000 2001 2002 119 *D009842 Oligopeptides D002918 Chymotrypsin Q000037 antagonists ; inhibitors Biochim Biophys Acta 289(1):187;1972 Biochim Biophys Acta 429(3):929;1976 Biokhimiia 1980;45(2):355 J Cell Physiol 1979;101(3):439 J Cell Physiol 86(1):131;1975 Methods Enzymol 45(B):685;1976 NLM MLH TPW M0042572 chymostatin C0055676 9076-44-2 D015842 Serine Proteinase Inhibitors T072575 chymostatin C002103 stendomycidin 1973 01 01 1993 05 03 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PEPTIDES (73-93) PYRIMIDINES (73-76) *D017561 Antibiotics, Peptide Biochemistry 11(22):4132;1972 NLM PML TPW M0042574 stendomycidin C0601301 21948-17-4 T072577 stendomycidin C002110 N,N-diethylbenzenesulfonamide 1973 01 01 1995 12 18 1996 1997 1998 1999 2000 2001 2002 0 DIETHYLAMINES (73-76) *D013449 Sulfonamides Toxicol Appl Pharmacol 23(3):376;1972 NLM MLH NLM M0042587 N,N-diethylbenzenesulfonamide C0601303 1709-50-8 T072590 N,N-diethylbenzenesulfonamide C010615 Nonidet P-40 1975 01 01 2001 08 17 1998 1999 2000 2000A 2001 2001A 2002 non-ionic detergent; RN given refers to parent cpd 508 *POLYETHYLENE GLYCOLS (75-79) *TRITONS (79-82) *D011092 Polyethylene Glycols Arch Virol 1980;63(3-4):209 Biochem Biophys Res Commun 64(2):736;1975 Biochemistry 12(11):2157;1973 Clin Chim Acta 1979;99(1):7 Contraception 13(4):498;1976 J Virol 24(3):821;1977 NLM CCR CCR M0056216 Nonidet P-40 C0068941 9036-19-5 T109 Organic Chemical T121 Pharmacologic Substance D003902 Detergents D013089 Spermatocidal Agents 68310-57-6 (K salt) M0056216 M0395831 M0056216 M0311171 M0056216 M0056214 M0056216 M0056215 T086219 Nonidet P-40 p-isomer in Merck Index, 9th ed, p.984, #7350 T418370 Non-Idet P-40 2000 07 06 T418371 NP-40 2000 07 06 M0395831 Igepal CA-630 C0968701 M0056216 M0395831 T418369 Igepal CA-630 2000 07 06 M0311171 Nonidet P-40, potassium salt C0952138 68310-57-6 M0056216 M0311171 T341171 Nonidet P-40, potassium salt 1999 08 18 M0056214 ORF 3617 C0134058 M0056216 M0056214 T086217 ORF 3617 M0056215 Triton X-114 C0146953 M0056216 M0056215 T086218 Triton X-114 C002119 morphine monohemisuccinate 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *MORPHINANS (73-75) SUCCINATES (73-76) *D009022 Morphine Derivatives Science 178(4061):647;1972 NLM NLM M0042603 morphine monohemisuccinate C0601310 36507-55-8 T072606 morphine monohemisuccinate C002138 3-deoxy-5-O-methyl-octulosonic acid 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 KETOSES (74-76) METHYLGLYCOSIDES (73-82) *D013400 Sugar Acids Eur J Biochem 29(1):184;1972 NLM VSR NLM M0042630 3-deoxy-5-O-methyl-octulosonic acid C0601325 0 T072633 3-deoxy-5-O-methyl-octulosonic acid C002142 carotenoic acid 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 FATTY ACIDS, UNSATURATED (73-76) *D002338 Carotenoids J Nutr 102(11):1437;1972 NLM NLM M0042634 carotenoic acid C0054817 0 T072637 carotenoic acid C002211 cetyl sulfate 1969 01 01 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 0 *ALKANES (74-79) *FATTY ALCOHOLS (72-74) *PALMITIC ACID (69-74) *D005233 Fatty Alcohols NLM TWD TWD M0042717 cetyl sulfate C0601355 143-02-2 1120-01-0 (Na salt) M0042717 M0307894 T072720 cetyl sulfate DATS M0307894 cetyl sulfate sodium salt C0951103 1120-01-0 M0042717 M0307894 T337894 cetyl sulfate sodium salt 1999 08 18 C002152 3-MPAM-ES 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ORGANOPHOSPHORUS COMPOUNDS (73-82) *D011220 Pralidoxime Compounds Comp Biochem Physiol (B) 42(3):429;1972 NLM VSR NLM M0042649 3-MPAM-ES C0601337 15129-49-4 M0042649 M0042648 T072652 3-MPAM-ES M0042648 3-O-(isopropylethylphosphono)acetyl-1-methylpyridinium iodide oxime C0601336 M0042649 M0042648 T072651 3-O-(isopropylethylphosphono)acetyl-1-methylpyridinium iodide oxime C002153 ara-fluorocytosine 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *FLUCYTOSINE (73-75) *NUCLEOSIDES (73-75) ARABINOSE (73-75) D003561 Cytarabine *Q000031 analogs ; derivatives Cancer Res 32(10):2269;1972 Cancer Treat Rep 61(4):617;1977 NLM NLM M0042650 ara-fluorocytosine C0052266 1-beta-D-arabinofuranosyl-5-fluorocytosine 4298-10-6 T072653 ara-fluorocytosine C002160 1-methyl-5-chloroindoline methylbromide 1971 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 AMMONIUM COMPOUNDS (71-76) *D007211 Indoles Jpn J Pharmacol 27:39;1977 NLM NLM M0042654 1-methyl-5-chloroindoline methylbromide C0044455 32179-45-6 T072657 1-methyl-5-chloroindoline methylbromide C069938 SIN1 protein 1991 08 19 2001 01 26 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a negative regulator of HO transcription; a non-specific DNA-binding protein related to HMG1; amino acid sequence given in first source 18 *D002868 Chromosomal Proteins, Non-Histone *D004268 DNA-Binding Proteins Mol Cell Biol 1991;11(8):4135 RLS WXM WXM M0190704 SIN1 protein C0142331 98002-35-8 T220709 SIN1 protein T220708 SPT2 gene product C002165 methyl-7,11-dichloro-3,7,11-trimethyl-2-dodeconate 1973 01 01 1982 09 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *FATTY ACIDS, UNSATURATED (73-75) *TERPENES (73-76) *D007848 Laurates D007605 Juvenile Hormones Z Naturforsch (C) 27(3):263;1972 NLM VSR NLM M0042657 methyl-7,11-dichloro-3,7,11-trimethyl-2-dodeconate C0601340 2-Dodecenoic acid, 7,11-dichloro-3,7,11-trimethyl-, methyl-t ester 35531-99-8 T072660 methyl-7,11-dichloro-3,7,11-trimethyl-2-dodeconate C002166 4-methyl-7-diethylaminocoumarin 1972 01 01 1997 05 23 1997 1998 1999 2000 2001 2002 4 DIETHYLAMINES (74-76) *D003374 Coumarins Biochim Biophys Acta 263(3):696;1972 NLM MLH NLM M0042658 4-methyl-7-diethylaminocoumarin C0048483 91-44-1 T072661 4-methyl-7-diethylaminocoumarin C069939 AGA protein 1991 08 19 2001 01 26 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 involved in cell surface attachment of the Saccharomyces cerevisiae cell adhesion glycoprotein alpha-agglutinin; amino acid sequence given in first source 6 *D005656 Fungal Proteins Mol Cell Biol 1991;11(8):4196 RLS WXM WXM M0190706 AGA protein C0101820 139532-53-9 T220711 AGA protein T220710 AGA gene product C002521 diphenylphosphorylcholine 1973 01 01 2001 01 26 1998 1999 2000 2001 2001A 2002 RN given refers to chloride 0 *CHOLINE (73-75) *ORGANOPHOSPHORUS CPDS (73-75) D010767 Phosphorylcholine *Q000031 analogs ; derivatives Pharmacology 7(5):292;1972 NLM TWD TWD M0043148 diphenylphosphorylcholine C0601492 39625-04-2 144-36-5 (iodide) M0043148 M0307974 T073151 diphenylphosphorylcholine M0307974 diphenylphosphorylcholine iodide C0951121 144-36-5 M0043148 M0307974 T337974 diphenylphosphorylcholine iodide 1999 08 18 C069988 proteoglycan-associated protein Ppl 1991 08 21 2001 01 26 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 Mw 19 kDa; from Legionella pneumophila; amino acid sequence given in first source 2 *D001425 Bacterial Outer Membrane Proteins *D011509 Proteoglycans Infect Immun 1991;59(8):2515 RLS WXM WXM M0190829 proteoglycan-associated protein Ppl C0138996 139660-56-3 T220834 proteoglycan-associated protein Ppl T220833 PplA protein C002180 sphydrofuran 1971 01 01 1997 07 28 1998 1999 2000 2001 2002 0 *FURANS (71-82) *GLYCERIN (71-75) D005990 Glycerol *Q000031 analogs ; derivatives NLM ADP BVL M0042673 sphydrofuran C0601344 Sphydrofuran 11072-19-8 M0042673 M0042672 T072676 sphydrofuran M0042672 2-methyl-4-(glyceryl)furan C0601343 M0042673 M0042672 T072675 2-methyl-4-(glyceryl)furan C002194 dehydrolysine 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 *LYSINE (73-75) D008239 Lysine *Q000031 analogs ; derivatives FEBS Letters 26(1):48;1972 NLM NLM M0042691 dehydrolysine C0601351 34069-68-6 T072694 dehydrolysine C002198 6-(4-hydroxyphenylazo)isocytosine 1972 01 01 1983 06 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 inhibits replication of DNA; Chemline contains another cpd of this name minus the 2-amino group (RN:39145-62-5) 0 *AZO CPDS (72-76) *CYTOSINE (72-75) PHENOLS (72-76) D003596 Cytosine *Q000031 analogs ; derivatives Nature (New Biol) 240(98):80;1972 NLM JSL NLM M0042696 6-(4-hydroxyphenylazo)isocytosine C0049462 2-amino-6-((4-hydroxyphenyl)azo)-4(1H)-pyrimidinone 40199-40-4 T072699 6-(4-hydroxyphenylazo)isocytosine C002230 1-methyladenosine 1973 01 01 2000 08 14 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 37 *ADENOSINE (73-75) ADENOSINE (73-75) METHANE (73-75) D000241 Adenosine *Q000031 analogs ; derivatives Exp Cell Res 75(1):79;1972 NLM CCR CCR M0042731 1-methyladenosine C0044462 15763-06-1 T114 Nucleic Acid, Nucleoside, or Nucleotide T072734 1-methyladenosine C070109 herpes simplex virus type 1 capsid protein ICP5 1991 08 30 2001 01 26 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 major capsid protein in HSV type-1 4 *D002213 Capsid Acta Virol (Praha) 1990;34(6):497 RLS WXM WXM M0191098 herpes simplex virus type 1 capsid protein ICP5 C0378944 0 T221103 herpes simplex virus type 1 capsid protein ICP5 T221102 HSV-1 capsid protein ICP5 C002203 8 beta-phenylacetamidohomoceph-4-em-5-carboxylic acid 1972 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ANTIBIOTICS (72-74) *THIEPINS (72-74) AZEPINES (72-74) PHENYLACETATES (72-82) *D002511 Cephalosporins Helv Chim Acta 1972;55(7):2567 NLM VSR NLM M0042707 8 beta-phenylacetamidohomoceph-4-em-5-carboxylic acid C0601353 0 T072710 8 beta-phenylacetamidohomoceph-4-em-5-carboxylic acid C069409 12(4-nitrobenzyl)-1,4,7,10-tetraazacyclotridecane-1,4,7-triacetic acid 1991 07 23 2000 08 15 1999 2000 2000A 2001 2002 structure given in first source 1 *D000088 Acetic Acids *D006571 Heterocyclic Compounds Bioconjug Chem 1990;1(5):345 RLS TWD TWD M0189457 12(4-nitrobenzyl)-1,4,7,10-tetraazacyclotridecane-1,4,7-triacetic acid C0646335 128924-92-5 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T219462 12(4-nitrobenzyl)-1,4,7,10-tetraazacyclotridecane-1,4,7-triacetic acid T219461 12-NBTATA C030812 adenosine 5'-O-(2-thiodiphosphate) 1981 07 31 2000 08 15 1995 1996 1997 1998 1999 2000 2000A 2001 2002 partial agonist toward platelet aggregation; see also record for 1-thiodiphosphate cpd 84 *D013873 Thionucleotides D000244 Adenosine Diphosphate *Q000031 analogs ; derivatives Br J Pharmacol 1981;73(2):405 RLS CCR CCR M0097211 adenosine 5'-O-(2-thiodiphosphate) C0050758 35094-45-2 T114 Nucleic Acid, Nucleoside, or Nucleotide 73536-95-5 (trilithium salt) M0097211 M0319028 M0097211 M0097202 M0097211 M0097205 T127215 adenosine 5'-O-(2-thiodiphosphate) T127213 adenosine-5'-O-(2-thiodiphosphate) T127211 ADP-S T127207 5'-ADPS M0319028 adenosine 5'-O-(2-thiodiphosphate), trilithium salt C0892005 73536-95-5 T114 Nucleic Acid, Nucleoside, or Nucleotide M0097211 M0319028 T349028 adenosine 5'-O-(2-thiodiphosphate), trilithium salt 1999 08 18 M0097202 (32S)adenosine 5'-O-(2-thiodiphosphate) C0214466 T114 Nucleic Acid, Nucleoside, or Nucleotide M0097211 M0097202 T127206 (32S)adenosine 5'-O-(2-thiodiphosphate) M0097205 ADP beta S C0106136 T114 Nucleic Acid, Nucleoside, or Nucleotide M0097211 M0097205 T127209 ADP beta S T127210 ADP beta-S T127212 ADPbetaS T127214 beta-thio-ADP T127208 5'-adenosine diphosphate beta-S C002207 geijerone 1973 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 naturally occurring C12 terpenoid from the essential oil of Juniperus communis L.; structure 0 *CYCLOHEXANES (73-75) *CYCLOHEXANONES (73-82) *D013729 Terpenes Helv Chim Acta 55(7):2429;1972 NLM VSR NLM M0042715 geijerone C0601354 3-isopropenyl-4-methyl-4-vinylcyclohexanone 41411-01-2 T072718 geijerone C411986 N-hydroxysuccinimidyl fluorescein-O-acetate 2000 08 15 2000 2001 2002 structure in first source 2 *D013388 Succinimides Anal Biochem. 2000 May 15;281(1):15-20 SZM SZM M0367859 N-hydroxysuccinimidyl fluorescein-O-acetate C0916425 0 T109 Organic Chemical M0367859 M0367860 T421722 N-hydroxysuccinimidyl fluorescein-O-acetate 2000 08 15 M0367860 SIFA cpd C0916900 M0367859 M0367860 T421723 SIFA cpd 2000 08 15 C002221 N-(4'-amino-n-butyl)-3-aminoacetylstrophanthidin 1973 01 01 1980 11 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 potent inhibitor of ATPase 0 *CARDANOLIDES (73-75) *D013328 Strophanthins J Biol Chem 247(23):7636;1972 NLM BGS NLM M0042722 N-(4'-amino-n-butyl)-3-aminoacetylstrophanthidin C0601356 Glycine, N-(4-aminobutyl)-, (3beta,5beta,14beta)-21,23-epoxy-5,14-dihydroxy-19,23-dioxo-24-norchol-20(22)-en-3-yl ester 40520-83-0 T072725 N-(4'-amino-n-butyl)-3-aminoacetylstrophanthidin C411987 git5 protein 2000 08 15 2000 2001 2002 The fission yeast git5 gene encodes a Gbeta subunit required for glucose-triggered adenylate cyclase activation; amino acid sequence in first source 3 *D020962 Heterotrimeric GTP-Binding Proteins Genetics 2000 Apr;154(4):1463-71 BMB BMB M0367861 git5 protein C0916426 0 T116 Amino Acid, Peptide, or Protein T421724 git5 protein 2000 08 15 T421725 git5 gene product 2000 08 15 C002226 diisopropylphosphate 1973 01 01 1997 12 17 1998 1999 2000 2001 2002 7 PROPANE (73-76) *D009943 Organophosphorus Compounds Proc Nat Acad Sci 69(11):3313;1972 NLM THA NLM M0042728 diisopropylphosphate C0058166 1611-31-0 T072731 diisopropylphosphate C029936 adenosine diphosphate-ferric chelate 1981 06 22 2000 08 15 1998 1999 2000 2000A 2001 2002 38 D000244 Adenosine Diphosphate *Q000031 analogs ; derivatives Biochem J 1980;192(3):861 RLS CCR CCR M0095101 adenosine diphosphate-ferric chelate C0050773 0 T114 Nucleic Acid, Nucleoside, or Nucleotide D007502 Iron Chelating Agents T125104 adenosine diphosphate-ferric chelate T125100 ADP-Fe chelate T125101 ADP-iron chelate T125102 Fe(3)-ADP T125103 ferric ADP C002233 ammonium metatungstate 1973 01 01 1993 08 12 1994 1995 1996 1997 1998 1999 2000 2001 2002 neutron gamma shield for californium 252; structure 0 AMMONIUM COMPOUNDS (73-76) TUNGSTEN (73-93) *D017973 Tungsten Compounds Health Physics 23(4):529;1972 NLM PML TPW M0042734 ammonium metatungstate C0601361 12028-48-7 T072737 ammonium metatungstate C002234 5-mercaptouracil-S-riboside 1974 01 01 1988 10 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D013891 Thiouridine D007536 Isomerism J Med Chem 15(12):1333;1972 NLM RGM NLM M0042735 5-mercaptouracil-S-riboside C0601362 S-ribofuranosyl-5-mercaptouracil 0 T072738 5-mercaptouracil-S-riboside C002241 20-methylpregn-5-en-3 beta-ol 1973 01 01 1998 05 28 1998 1999 2000 2001 2002 RN given refers to (3beta)-isomer; structure 3 HYDROXYSTEROIDS (73-76) *D011283 Pregnenes Biochem J 128(2):467;1972 NLM BQV NLM M0042749 20-methylpregn-5-en-3 beta-ol C0046625 1042-59-7 M0042749 M0042746 M0042749 M0042745 M0042749 M0042747 M0042749 M0042748 T072752 20-methylpregn-5-en-3 beta-ol M0042746 23,24-dinor-5-cholen-3-ol C0093903 M0042749 M0042746 T072749 23,24-dinor-5-cholen-3-ol M0042745 20-methyl-5-pregnen-3beta-ol C0093828 M0042749 M0042745 T072748 20-methyl-5-pregnen-3beta-ol M0042747 23,24-dinorchol-5-en-3beta-ol C0093905 M0042749 M0042747 T072750 23,24-dinorchol-5-en-3beta-ol M0042748 guneribol C0120510 M0042749 M0042748 T072751 guneribol C002242 beta-apo-8'-carotenyl acetate epoxide 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ETHERS, CYCLIC (73-76) *D002338 Carotenoids Int J Vit Nutr Res 42(3):379;1972 NLM NLM M0042750 beta-apo-8'-carotenyl acetate epoxide C0601366 0 T072753 beta-apo-8'-carotenyl acetate epoxide C002248 29-methylisofucosterol 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 CHOLESTENES (73-76) *D010840 Phytosterols Steroids 18(5):545;1971 NLM NLM M0042759 29-methylisofucosterol C0601375 Cholest-5-en-3-ol, 24-propylidene-, (3beta,24Z)- 35339-71-0 M0042759 M0042758 T072762 29-methylisofucosterol M0042758 24-propylidenecholest-5-en-3 beta-ol C0601374 M0042759 M0042758 T072761 24-propylidenecholest-5-en-3 beta-ol C002257 3'-O-methylneamine 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *NEOMYCIN (72-75) METHYL ETHER (74-75) D009355 Neomycin *Q000031 analogs ; derivatives J Antibiot (Tokyo) 25(5):322;1972 NLM NLM M0042773 3'-O-methylneamine C0601383 D-Streptamine, 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-3-O-methyl-alpha-D-glucopyranosyl)- 37085-86-2 T072776 3'-O-methylneamine C002258 4'-O-methylneamine 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *NEOMYCIN (72-75) METHYL ETHER (72-75) D009355 Neomycin *Q000031 analogs ; derivatives J Antibiot (Tokyo) 25(5):322;1972 NLM NLM M0042774 4'-O-methylneamine C0601384 D-Streptamine, 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-4-O-methyl-alpha-D-glucopyranosyl)- 37085-87-3 T072777 4'-O-methylneamine C002261 N-methyl-N-nitroso-beta-D-galactosylamine 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 GALACTOSAMINE (72-75) *D009602 Nitrosamines D005688 Galactosamine *Q000031 analogs ; derivatives Z Krebsforsch 75(4):296;1971 NLM NLM M0042779 N-methyl-N-nitroso-beta-D-galactosylamine C0601385 beta-D-Galactopyranosylamine, N-methyl-N-nitroso- 31364-57-5 T072782 N-methyl-N-nitroso-beta-D-galactosylamine C002262 N-methyl-N-nitroso-beta-D-glucosylamine 1972 01 01 1982 10 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *GLUCOSAMINE (72-75) GLUCOSAMINE/*analogs (75-82) *D009602 Nitrosamines Z Krebsforsch 75(4):296;1971 NLM VSR NLM M0042780 N-methyl-N-nitroso-beta-D-glucosylamine C0601386 beta-D-Glucopyranosylamine, N-methyl-N-nitroso- 31364-55-3 T072783 N-methyl-N-nitroso-beta-D-glucosylamine C002270 beta-(2-methoxyphenoxy)lactic acid 1973 01 01 1983 05 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 metabolite of glyceryl guaiacolate 2 *LACTATES (73-76) CATECHOLS (75-76) D006140 Guaiacol Glyceryl Ether *Q000031 analogs ; derivatives J Pharm Sci 61(12):1997;1972 NLM DLJ NLM M0042792 beta-(2-methoxyphenoxy)lactic acid C0053367 13057-65-3 T072795 beta-(2-methoxyphenoxy)lactic acid C002313 PAcein 1973 01 01 2001 02 23 1998 1999 2000 2001 2001A 2002 structure 73 RESORCINOLS (75-76) *D010078 Oxazines Acta Hepatogastroenterol (Stuttg) 23(6):412;1976 Acta Morphol Acad Sci Hung 20(1):97;1972 Acta Pathol Microbiol Scand A 86(5):383;1978 Am J Clin Pathol 69(5):548;1978 Gastroenterol Clin Biol 1(2):127;1977 Gastroenterology 71(1):102;1976 Histochemistry 1979;64(2):119 J Assoc Physicians India 1979;27(6):535 J Assoc Physicians India 1979;27(6):563 J Cutan Pathol 5(1):37;1978 Jpn J Gastroenterol 75(8):1190;1978 Lancet 1(8078):1338;1978 Lancet 1(8128):1203;1979 Virchows Arch Pathol Anat 369(3):239;1976 Yonsei Med J 19(2):56;1978 NLM BMB BMB M0042864 PAcein C0069596 1400-62-0 D004396 Dyes T072867 PAcein Merck Index, 9th ed, p. 891, #6704 T436919 orcein 2001 02 23 C002346 O-methyl threonine 1971 01 01 2000 07 31 2001 2002 RN given refers to cpd without isomeric designation 2 *THREONINE (71-75) D013912 Threonine *Q000031 analogs ; derivatives NLM CCR sjn M0042890 O-methyl threonine C0069265 4385-90-4 T116 Amino Acid, Peptide, or Protein 4144-02-9 ((L-Thr)-isomer) M0042890 M0307927 T072893 O-methyl threonine M0307927 O-methyl threonine, (L-Thr)-isomer C0894218 4144-02-9 T116 Amino Acid, Peptide, or Protein M0042890 M0307927 T337927 O-methyl threonine, (L-Thr)-isomer 1999 08 18 C002281 raphanatin 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 metabolite of zeatin 0 *GLYCOSIDES (73-75) *PURINE NUCLEOSIDES (75-76) *PURINES (73-75) BUTYLAMINES (73-75) D015026 Zeatin *Q000031 analogs ; derivatives Biochem Biophys Res Commun 49(2):460;1972 NLM RLS NLM M0042812 raphanatin C0601396 38165-56-9 M0042812 M0042811 T072815 raphanatin M0042811 7-beta-D-glucopyranosylzeatin C0601395 M0042812 M0042811 T072814 7-beta-D-glucopyranosylzeatin C115844 1-methyl-5-oxobicyclo(2,2,1)heptane-2,3-dicarboximide 1998 12 10 2001 04 23 1999 2000 2000A 2001 2001A 2002 structure in first source 1 *D001643 Bicyclo Compounds *D007094 Imides Acta Pol Pharm 1998 Jul-Aug;55(4):315-8 SZM TWD TWD M0298101 1-methyl-5-oxobicyclo(2,2,1)heptane-2,3-dicarboximide C0760358 0 T328106 1-methyl-5-oxobicyclo(2,2,1)heptane-2,3-dicarboximide T328105 MOH-dicarboximide C002295 bursicon 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 5 *D007447 Invertebrate Hormones Biochim Biophys Acta 290(1):424;1972 NLM NLM M0042836 bursicon C0081863 9041-06-9 T072839 bursicon C115930 2-methyl-4,9-dihydro-1-(4-bromophenyl)-1H-imidazo(4,5-g)quinoxaline-4,9-dione 1998 12 14 2001 04 23 1999 2000 2000A 2001 2001A 2002 structure in first source 1 *D007093 Imidazoles *D011810 Quinoxalines J Med Chem 1998 Nov 19;41(24):4716-22 THA TWD TWD M0298298 2-methyl-4,9-dihydro-1-(4-bromophenyl)-1H-imidazo(4,5-g)quinoxaline-4,9-dione C0760555 0 T328303 2-methyl-4,9-dihydro-1-(4-bromophenyl)-1H-imidazo(4,5-g)quinoxaline-4,9-dione T328302 2-methyl-1-BrPh-IQD C115933 (1,1-dioxido--3-oxo-1,2-benzisothiazol-2(3H)-yl)methyl 4-(((phenylmethoxy)carbonyl)amino)benzoate 1998 12 14 2001 04 23 1999 2000 2001 2001A 2002 tryptase inhibitor; structure in first source 1 *D003499 Cyclic S-Oxides *D013844 Thiazoles J Med Chem 1998 Nov 19;41(24):4854-60 THA TWD TWD M0298305 (1,1-dioxido--3-oxo-1,2-benzisothiazol-2(3H)-yl)methyl 4-(((phenylmethoxy)carbonyl)amino)benzoate C0760562 0 T328310 (1,1-dioxido--3-oxo-1,2-benzisothiazol-2(3H)-yl)methyl 4-(((phenylmethoxy)carbonyl)amino)benzoate T328309 DOBTY 4-PhMeOCA-PhCOOH C105069 SUN1 protein 1997 04 11 2001 02 23 1998 1999 2000 2001 2001A 2002 can suppress null nin1 mutation; amino acid sequence given in first source; GenBank D78022 3 *D005656 Fungal Proteins *D012097 Repressor Proteins D012441 Saccharomyces cerevisiae Mol Biol Cell 1997 Jan;8(1):171-87 BMB WXM WXM M0274232 SUN1 protein C0537187 0 T304237 SUN1 protein T304236 SUN1 gene product C105074 Mist1 protein 1997 04 11 2001 02 23 1998 1999 2000 2001 2001A 2002 MW 22 kDa; binds to E-box sequences; amino acid sequence given in first source; GenBank U58275 8 *D014157 Transcription Factors D018257 Helix-Loop-Helix Motifs Dev Biol 1997 Feb 1;182(1):101-13 PML WXM WXM M0274246 Mist1 protein C0537201 0 T304251 Mist1 protein T304250 mist1 gene product C002307 cyclic ara-CMP 1973 01 01 1993 08 19 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CYTARABINE (73-75) *CYTOSINE NUCLEOTIDES (73-76) *NUCLEOTIDES, CYCLIC (74-80) D003561 Cytarabine *Q000031 analogs ; derivatives D003563 Cyclic CMP *Q000031 analogs ; derivatives Res Commun Chem Pathol Pharmacol 4(3):631;1972 NLM TPW TPW M0042861 cyclic ara-CMP C0601410 1-beta-D-arabinofuranosylcytosine 3',5'-cyclic monophosphate 37764-45-7 T072864 cyclic ara-CMP C002310 phenoxymethylanhydropenicillin 1973 01 01 1991 10 01 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PENICILLIN, PHENOXYMETHYL (73-75) D010404 Penicillin V *Q000031 analogs ; derivatives J Am Chem Soc 94(24):8557;1972 NLM AJC TPW M0042862 phenoxymethylanhydropenicillin C0601411 Acetamide, N-(2-(1-methylethylidene)-3,7-dioxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenoxy-, (5R-trans)- 47295-33-0 T072865 phenoxymethylanhydropenicillin C109663 caspase-activated deoxyribonuclease 1998 01 14 2001 02 23 1998 1999 2000 2001 2001A 2002 degrades DNA during apoptosis, inhibited by ICAD (inhibitor of CAD); a protein of 343 amino acids carrying a nuclear localization signal; amino acid sequence in first source 46 *D003851 Deoxyribonucleases D017209 Apoptosis Nature 1998 Jan 1;391(6662):43-50 BMB CCR CCR M0284533 caspase-activated deoxyribonuclease C0669174 EC 3.1.- T314538 caspase-activated deoxyribonuclease T314537 caspase-activated DNase T314536 CAD enzyme C115934 pyrrolidyl-2-pyrrolidyl-5-(trifluoromethyl)benzenesulfonamide 1998 12 14 2001 04 23 1999 2000 2000A 2001 2001A 2002 structure in first source 1 *D011759 Pyrrolidines *D013449 Sulfonamides J Med Chem 1998 Nov 19;41(24):4885-9 THA TWD TWD M0298307 pyrrolidyl-2-pyrrolidyl-5-(trifluoromethyl)benzenesulfonamide C0760564 0 T328312 pyrrolidyl-2-pyrrolidyl-5-(trifluoromethyl)benzenesulfonamide T328311 PP3FMe-benzenesulfonamide C002318 3-bromophenylsuccinimide 1974 01 01 1983 06 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 5 BROMOBENZENES (75-76) *D013388 Succinimides Acta Polon Pharm 32(3):379;1975 Neur Neurchir Pol 6(5):755;1972 NLM DLJ NLM M0042874 3-bromophenylsuccinimide C0047266 22855-57-8 M0042874 M0042873 M0042874 M0042872 T072877 3-bromophenylsuccinimide M0042873 m-bromophenylsuccinimide C0126591 M0042874 M0042873 T072876 m-bromophenylsuccinimide M0042872 lefadol C0125441 M0042874 M0042872 T072875 lefadol C002319 phenylthiodiphenylpenicillin 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 SULFIDES (73-76) *D010406 Penicillins Can J Physiol Pharmacol 50(10):986;1972 NLM NLM M0042875 phenylthiodiphenylpenicillin C0601413 38964-63-5 T072878 phenylthiodiphenylpenicillin C002339 4-methyl-1,2,3,4-tetrahydrodibenzo-1,4- diazepino(2,1-c)-1,4-thiazepine 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D003987 Dibenzothiazepines J Pharm Soc Jpn 9(11):1228;1971 NLM NLM M0042877 4-methyl-1,2,3,4-tetrahydrodibenzo-1,4- diazepino(2,1-c)-1,4-thiazepine C0601414 0 T072880 4-methyl-1,2,3,4-tetrahydrodibenzo-1,4- diazepino(2,1-c)-1,4-thiazepine C032506 somatotropin (1-134) 1981 12 14 2001 04 23 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 *D010446 Peptide Fragments *D013006 Growth Hormone Endocrinology 1981;109(5):1663 MEG CCR CCR M0101441 somatotropin (1-134) C0614931 1-134-Somatotropin 53528-53-3 T131445 somatotropin (1-134) T131443 HGH (1-134) T131444 human growth hormone (1-134) C032507 somatotropin (135-191) 1981 12 14 2001 04 23 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 *D010446 Peptide Fragments *D013006 Growth Hormone Endocrinology 1981;109(5):1663 MEG CCR CCR M0101444 somatotropin (135-191) C0614934 80738-38-1 T131448 somatotropin (135-191) T131446 HGH (135-191) T131447 human growth hormone (135-191) C002342 methylthiobutyric acid 1971 01 01 1982 09 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *BUTYRATES (71-75) SULFIDES (71-82) *D002088 Butyric Acids D006133 Growth Substances NLM VSR NLM M0042881 methylthiobutyric acid C0601417 32391-97-2 T072884 methylthiobutyric acid C114290 1-methyl-2-thietaniumcarboxylic acid 1998 09 18 2000 07 24 1998 1999 2000 2000A 2001 2002 structure in first source 1 *D002264 Carboxylic Acids *D006571 Heterocyclic Compounds Chem Res Toxicol 1998 Jul;11(7):794-9 THA SXD SXD M0294819 1-methyl-2-thietaniumcarboxylic acid C0757106 0 T324824 1-methyl-2-thietaniumcarboxylic acid C002347 3-methylthymine 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *THYMINE (72-75) D013941 Thymine *Q000031 analogs ; derivatives Chem Biol Interactions 4(3):149;1972 NLM NLM M0042891 3-methylthymine C0047616 4160-77-4 T072894 3-methylthymine C032835 alpha-N-acetyl beta-endorphin (1-26) 1981 12 31 2001 04 23 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 2 *ENDORPHINS (81-87) *D010446 Peptide Fragments D001615 beta-Endorphin *Q000031 analogs ; derivatives Biochem Biophys Res Commun 1981;102(3):897 NBM CCR CCR M0102183 alpha-N-acetyl beta-endorphin (1-26) C0051434 beta-Endorphin, N-acetyl-27-de-L-histidine-28-de-L-lysine-29-de-L-lysine-30-deglycine-31-de-L-glutamine- 78325-28-7 T132187 alpha-N-acetyl beta-endorphin (1-26) T132186 alpha-N-acetyl beta-endorphin(1-26) T132185 ANAC-BE26 C110292 1-O-(indole-3-acetyl)glucose 1998 02 16 2000 07 24 1998 1999 2000 2000A 2001 2002 1 *D005960 Glucosides *D007211 Indoles Acta Biochim Pol 1997;44(2):215-20 THA SXD SXD M0285970 1-O-(indole-3-acetyl)glucose C0670591 0 T315975 1-O-(indole-3-acetyl)glucose C002352 methylurea 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 26 *UREA (72-75) *D008782 Methylurea Compounds Am J Physiol 222(4):801;1972 NLM NLM M0042898 methylurea C0066446 598-50-5 T072901 methylurea C002353 6-methyluridine 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *URIDINE (72-75) D014529 Uridine *Q000031 analogs ; derivatives Nature (London) 235(333);1972 NLM NLM M0042899 6-methyluridine C0601422 16710-13-7 T072902 6-methyluridine C002356 Mexaform 1971 01 01 1992 06 18 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains 4,7-phenanthroline-5,6-dione ; iodochlorhydroxyquin; used in treatment of non-specific enteritis; structure 1 *D007464 Clioquinol *D010618 Phenanthrolines D004338 Drug Combinations D010115 Oxyphenonium Curr Ther Res 18(4):546;1975 J Assoc Physicians India 24(2):95;1976 Pediatriia 7:38;1976 NLM MLH TPW M0042900 Mexaform C0066488 8056-07-3 T072903 Mexaform C002357 Mexase 1972 01 01 1992 06 18 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains bromelain, pancreatin, dehydrocholic acid, iodochlorhydroquin, 4,7-phenanthroline-5,6-dione used in treatment of non-specific enteritis 0 *D001963 Bromelains *D003685 Dehydrocholic Acid *D007464 Clioquinol *D010194 Pancreatin *D010618 Phenanthrolines D004338 Drug Combinations Vrach Delo 5:137;1977 Vrach Delo 6:78;1976 Z Allgemeinmed 46(9):482;1970 NLM MLH TPW M0042901 Mexase C0066489 Cholan-24-oic acid, 3,7,12-trioxo-, (5beta)-, mixt. with 5-chloro-7-iodo-8-quinolinol, pancreatin, 4,7-phenanthroline-5,6-dione and stem bromelain 99753-54-5 T072904 Mexase C002359 Midalgyl 1972 01 01 1986 08 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains proxifezone, cresotamide; suppositories also contain ascorbic acid 0 *D000700 Analgesics *D010653 Phenylbutazone *D011431 Propoxyphene *D012457 Salicylamides D004338 Drug Combinations D001205 Ascorbic Acid NLM THA NLM M0042902 Midalgyl C0066530 0 T072905 Midalgyl C002383 morpholinomethylphenol 1971 01 01 1983 08 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *MORPHOLINES (71-82) *D010636 Phenols NLM ACS NLM M0042929 morpholinomethylphenol C0601429 4-(3-methyl-2-morpholinyl)phenol 54804-09-0 T072932 morpholinomethylphenol C113805 1-octen-3-one 1998 08 21 2000 07 24 1998 1999 2000 2000A 2001 2002 structure in first source 3 *D007659 Ketones Eur J Biochem 1998 Jul 1;255(1):271-8 THA SXD SXD M0293743 1-octen-3-one C0756032 4312-99-6 T323748 1-octen-3-one C002392 muldamine 1972 01 01 1983 07 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *VERATRUM (72-79) *D014704 Veratrum Alkaloids Lipids 13(10):708;1978 Steroids 18(6):741;1971 NLM JSL NLM M0042949 muldamine C0066926 36069-45-1 M0042949 M0042948 T072952 muldamine M0042948 5-veratramine-3 beta,11 alpha-diol-11-acetate C0098692 M0042949 M0042948 T072951 5-veratramine-3 beta,11 alpha-diol-11-acetate C002396 mycobactin S 1971 01 01 1997 07 16 1998 1999 2000 2001 2002 0 *MYCOBACTERIUM (71-82) *SALICYLIC ACIDS (71-75) *D010080 Oxazoles Biochim Biophys Acta 385(2):209;1975 NLM NNS BVL M0042952 mycobactin S C0067007 26769-11-9 T072955 mycobactin S C002398 myosmine 1972 01 01 1981 06 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 alkaloid found in Nicotiana; structure 5 *PYRROLES (73-76) PYRIDINES (72-81) *D000470 Alkaloids J Org Chem 37(10):1635;1972 NLM NBM NLM M0042953 myosmine C0067063 532-12-7 T072956 myosmine C002401 cholesta-8,14-diene-3-beta-ol 1974 01 01 1978 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CHOLESTADIENOLS (74-78) *D003684 Dehydrocholesterols Biochem J 129(2):225;1972 NLM NLM M0042959 cholesta-8,14-diene-3-beta-ol C0601432 17608-73-0 T072962 cholesta-8,14-diene-3-beta-ol C002402 cholesta-7,9-dien-3-beta-ol 1974 01 01 1978 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CHOLESTADIENOLS (74-77) *D003684 Dehydrocholesterols Biochem J 129(2):225;1972 NLM NLM M0042960 cholesta-7,9-dien-3-beta-ol C0601433 566-96-1 T072963 cholesta-7,9-dien-3-beta-ol C002408 cis-4-hydroxydodec-6-enoic acid lactone 1973 01 01 1997 03 25 1997 1998 1999 2000 2001 2002 0 *FATTY ACIDS, UNSATURATED (73-87) *LACTONES (73-82) HYDROXY ACIDS (75-76) *D005229 Fatty Acids, Monounsaturated Biol Reprod 4:344;1971 NLM TBT NLM M0042965 cis-4-hydroxydodec-6-enoic acid lactone C0601434 18679-18-0 T072968 cis-4-hydroxydodec-6-enoic acid lactone C002470 podocarpic acid 1973 01 01 2000 06 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 structure 5 CARBOXYLIC ACIDS (73-76) *D010616 Phenanthrenes J Org Chem 37(25):4212;1972 NLM CCR CCR M0043066 podocarpic acid C0071319 5947-49-9 T109 Organic Chemical T073069 podocarpic acid C002459 D 048 1973 01 01 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 *PHENOLS (73-74) SULFITES (73-75) *D010647 Phenyl Ethers J Ag Food Chem 21(1):98;1972 NLM TWD TWD M0043058 D 048 C0601461 1-(2-butynyl)-1-(p-tert-butylphenoxy)-2-butyl sulfite 40642-27-1 T073061 D 048 T073060 D-048 C418973 pronapsin 2001 01 27 2001 2002 amino acid sequence in first source 1 *D004792 Enzyme Precursors *D016282 Aspartic Endopeptidases Eur J Biochem 2000 Dec;267(23):6921-30 THA THA M0377330 pronapsin C0963542 EC 3.4.23.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T434346 pronapsin 2001 01 27 C418974 scurfin 2001 01 27 2001 2002 a forkhead/winged-helix protein whose disruption results in fatal lymphoproliferative disorder of the scurfy mouse; amino acid sequence in first source; GenBank AF277993 (human) and AF277991 10 *D004268 DNA-Binding Proteins Nat Genet 201 Jan;27(1):68-73 THA THA M0377331 scurfin C0963543 0 T116 Amino Acid, Peptide, or Protein T434347 scurfin 2001 01 27 T434348 foxp3 gene product 2001 01 27 C002422 showdomycin 5'-phosphate 1973 01 01 1982 07 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *RIBONUCLEOTIDES (73-75) MALEIMIDES (73-75) D012787 Showdomycin Q000031 analogs ; derivatives D013439 Sulfhydryl Reagents Biochem Biophys Res Commun 49(4):1007;1972 Cancer Lett 4:259;1978 NLM ESH NLM M0043001 showdomycin 5'-phosphate C0074463 40853-66-5 T073004 showdomycin 5'-phosphate C002423 mannophosphoinositide 1973 01 01 1993 08 19 1994 1995 1996 1997 1998 1999 2000 2001 2002 10 *PHOSPHOINOSITIDES (77-93) MANNOSE (73-76) *D010716 Phosphatidylinositols Am Rev Respir Dis 106(6):892;1972 NLM TPW TPW M0043002 mannophosphoinositide C0065675 0 T073005 mannophosphoinositide C418975 ELOVL4 protein 2001 01 27 2001 2002 a retinal photoreceptor-specific protein that may be involved in fatty acid elongation in photoreceptor cells; amino acid sequence in first source; GenBank AF277094 (human) and AF277093 (mouse) 6 *D005136 Eye Proteins *D008565 Membrane Proteins Nat Genet 201 Jan;27(1):89-93 THA THA M0377332 ELOVL4 protein C0963544 0 T116 Amino Acid, Peptide, or Protein T434349 ELOVL4 protein 2001 01 27 T434350 ELOVL4 gene product 2001 01 27 C418976 protocadherin 15 2001 01 27 2001 2002 has been sequenced; GenBank AF281899 4 *D011498 Protein Precursors *D015820 Cadherins Nat Genet 201 Jan;27(1):99-102 THA THA M0377333 protocadherin 15 C0963545 0 T116 Amino Acid, Peptide, or Protein T434351 protocadherin 15 2001 01 27 T434352 protocadherin Pcdh15 2001 01 27 T434353 Pcdh15 protein 2001 01 27 C002428 estrobin 1973 01 01 1982 07 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ESTROGENS (73-76) PHENYL ETHERS (74-76) *D013267 Stilbenes D004969 Estrogens, Synthetic Genetika 13(12):2159;1977 NLM CHA NLM M0043014 estrobin C0059652 Benzene, 1,1'-(bromophenylethenylidene)bis(4-ethoxy- 60883-74-1 M0043014 M0043013 M0043014 M0043012 T073017 estrobin Negwer #4261, p. 702 M0043013 triphenylstilbene C0146882 M0043014 M0043013 T073016 triphenylstilbene M0043012 oestrobin1,1-bis(p-ethoxyphenyl)-2-bromo-2-phenylethylene C0133728 M0043014 M0043012 T073015 oestrobin1,1-bis(p-ethoxyphenyl)-2-bromo-2-phenylethylene C002432 2-methyl-4-dimethylaminoazobenzene 1973 01 01 1982 07 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 6 *DIMETHYLAMINOAZOBENZENE (73-75) METHANE (73-75) *D008749 Methyldimethylaminoazobenzene D007536 Isomerism Cancer Res 32(9):1878;1972 NLM VSR NLM M0043018 2-methyl-4-dimethylaminoazobenzene C0046342 54-88-6 T073021 2-methyl-4-dimethylaminoazobenzene C002434 debestran 1973 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ESTROGENS (73-76) CYCLOHEXANES (73-76) *D013267 Stilbenes D004969 Estrogens, Synthetic NLM VSR NLM M0043019 debestran C0601455 1-(p-ethoxycyclohexyl)-1-(p-ethoxyphenyl)-2- bromo-1-phenylethylene 60883-77-4 T073022 debestran Negwer #4282 C002437 2-(4'-hydroxyazobenzene)benzoic acid 1973 01 01 1997 09 02 1997 1998 1999 2000 2001 2002 4 BENZOATES (73-82) PHENOLS (73-76) *D001391 Azo Compounds Clin Biochem 8(4):273;1975 Clin Chem 18(12):1537;1972 J Pediatr 90(4):642;1977 NLM MLH NLM M0043020 2-(4'-hydroxyazobenzene)benzoic acid C0045710 29533-13-9 T073023 2-(4'-hydroxyazobenzene)benzoic acid C002438 2-methyl-3-carbethoxy-4-(3-propionic acid)pyrrole 1973 01 01 1997 09 02 1997 1998 1999 2000 2001 2002 0 PROPIONATES (73-75) PROPIONIC ACIDS (75-83) *D011758 Pyrroles Clin Chem 18(12):1534;1972 NLM MLH NLM M0043021 2-methyl-3-carbethoxy-4-(3-propionic acid)pyrrole C0601456 38664-16-3 T073024 2-methyl-3-carbethoxy-4-(3-propionic acid)pyrrole C418977 cadherin 23 2001 01 27 2001 2002 has been sequenced; GenBank AF308939 8 *D015820 Cadherins Nat Genet 201 Jan;27(1):103-7 THA THA M0377334 cadherin 23 C0963546 0 T116 Amino Acid, Peptide, or Protein T434354 cadherin 23 2001 01 27 T434355 Cdh23 protein 2001 01 27 C071899 TMV 130k protein 1992 01 06 2001 08 07 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2000B 2001 2001A 2002 126-kDa protein encoded by same ORF as 130-kDa form; possesses methyltransferase and helicase-like domains 4 *D014764 Viral Proteins D014027 Tobacco Mosaic Virus Virology 1991;185(2)580 BXB CCR CCR M0195035 TMV 130k protein C0146105 0 M0195035 M0365111 T225040 TMV 130k protein T225039 tobacco mosaic virus 130k protein M0365111 126-kDa protein, TMV C0905062 M0195035 M0365111 T418009 126-kDa protein, TMV 2000 06 28 T418008 TMV 126-kDa protein 2000 06 28 C097590 GW 3600 1996 02 12 2001 08 07 1996 1997 1998 1999 2000 2001 2001A 2002 a selective inhibitor of cAMP-specific phosphodiesterase type IV (PDE4); structure given in first source 2 *D011759 Pyrrolidines D010726 Phosphodiesterase Inhibitors J Med Chem 1995 Dec 22;38(26):4972-5 PML TWD TWD M0256516 GW 3600 C0385675 0 M0256516 M0256515 T286521 GW 3600 T286518 GW-3600 T286519 GW3600 M0256515 methyl 3-acetyl-4-(3-(cyclopentyloxy)-4-methoxyphenyl)-3-methyl-1-pyrrolidinecarboxylate C0385677 M0256516 M0256515 T286520 methyl 3-acetyl-4-(3-(cyclopentyloxy)-4-methoxyphenyl)-3-methyl-1-pyrrolidinecarboxylate C002451 1,3-dimethyluracil 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 11 *URACIL (73-75) D014498 Uracil *Q000031 analogs ; derivatives Biophys Chem 8:151;1978 Photochem Photobiol 16(6):465;1972 NLM NLM M0043050 1,3-dimethyluracil C0043943 874-14-6 T073053 1,3-dimethyluracil C418978 lipin protein 2001 01 27 2001 2002 has been sequenced; GenBank AF180471; do not confuse with lipine, also known as lipin 2 *D009687 Nuclear Proteins Nat Genet 201 Jan;27(1):121-4 THA THA M0377335 lipin protein C0963547 0 T116 Amino Acid, Peptide, or Protein T434356 lipin protein 2001 01 27 T434357 Lpin1 gene product 2001 01 27 C002457 polyoxin 1973 01 01 1994 06 10 1994 1995 1996 1997 1998 1999 2000 2001 2002 antifungal antibiotics produced by Streptomyces cacaoi var asoensis; group of peptide-pyrimidine nucleoside antibiotics 15 PEPTIDES (73-93) D011741 Pyrimidine Nucleosides Biochemistry 16(14):3121;1977 Chem Pharm Bull (Tokyo) 25(7):1740;1977 Environ Qual Saf 5:49;1976 J Am Chem Soc 91:7490;1969 J Chem Soc (Perkin I) 12:1472;1977 J Org Chem 37(26):4391;1972 Pesticides 3:439;1975 NLM BVL TPW M0043055 polyoxin C0071635 11113-80-7 T073058 polyoxin C002464 tetrodamine 1973 01 01 1983 08 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 intermediate in synthesis of tetrodotoxin; RN from 9th CI; cpd not in Chemline 8/83; structure 0 *TETRODOTOXIN (73-75) D013779 Tetrodotoxin *Q000031 analogs ; derivatives J Am Chem Soc 94(26):9217;1972 NLM ACS NLM M0043060 tetrodamine C0601462 41963-49-9 T073063 tetrodamine C002469 fusarenon-X 1973 01 01 1982 08 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 mycotoxin isolated from Fusarium nivale; belongs to 12,13-epoxytrichothecene group; structure 32 *SESQUITERPENES (74-75) FUSARIUM (73-76) *D014255 Trichothecenes D009183 Mycotoxins Biochim Biophys Acta 287(3):520;1972 Biochim Biophys Acta 383(2):207;1975 Eur J Biochem 84:103;1978 IARC Monogr Eval Carcinog Risk Chem Man 11:169;1976 Jpn Med Sci Biol 1979;32(4):189 Toxicol Appl Pharmacol 1979;50(1):87 NLM VSR NLM M0043065 fusarenon-X C0060880 12,13-epoxy-3 alpha,4 beta,7 beta,15-tetrahydroxytrichothec-9-en-8-one 4-acetate 23255-69-8 T073068 fusarenon-X C002481 isohomofolic acid 1972 01 01 1984 08 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *FOLIC ACID (72-75) *HOMOFOLIC ACID (75-84) ISOMERISM (72-74) *D005492 Folic Acid Mol Pharmacol 8(6):740;1972 NLM GTC NLM M0043084 isohomofolic acid C0601467 N-(4-((((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)methyl)benzoyl)-L-glutamic acid 24960-28-9 T073087 isohomofolic acid C002482 isohomoaminopterin 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *AMINOPTERIN (73-75) ISOMERISM (73-74) D000630 Aminopterin *Q000031 analogs ; derivatives Mol Pharmacol 8(6):740;1972 NLM NLM M0043085 isohomoaminopterin C0601468 N-(4-((((2,4-diamino-6-pteridinyl)methyl)amino)methyl)benzoyl)-L-glutamic acid 39271-61-9 T073088 isohomoaminopterin C002495 Ro 4-1398 1973 01 01 1995 09 15 1996 1997 1998 1999 2000 2001 2002 structure 0 *D011807 Quinolizines Arzneim Forsch 22(9):1474;1972 NLM BVL BVL M0043116 Ro 4-1398 C0601477 2-hydroxy-2-(3'-methoxybutyl)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-benzoquinolizine.HCl 37819-46-8 T073119 Ro 4-1398 C002500 aranotin 1973 01 01 1981 09 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *OXEPINS (73-79) *PIPERAZINES (73-81) D010879 Piperazines Chem Ber 105(2):625;1972 J Org Chem 42(6):948;1977 NLM NBM NLM M0043129 aranotin C0052306 19885-51-9 T073132 aranotin C002507 bracteoline 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 METHYL ETHER (73-76) *D001060 Aporphines Chem Ber 105(2):609;1972 NLM NLM M0043134 bracteoline C0601482 25651-04-1 T073137 bracteoline C002585 2-hydroxyphytanic acid 1973 01 01 2001 01 26 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 7 *FATTY ACIDS (73-75) FATTY ALCOHOLS (74-75) HYDROXY ACIDS (75-76) D010831 Phytanic Acid *Q000031 analogs ; derivatives J Biol Chem 248(3):1091;1973 NLM TWD TWD M0043244 2-hydroxyphytanic acid C0046234 2-hydroxy-3,7,11,15-tetramethylhexadecanoic acid 14721-68-7 T073247 2-hydroxyphytanic acid T073246 alpha-hydroxyphytanic acid C041205 aflatoxin Q2a-bovine serum albumin 1984 05 23 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 *D000348 Aflatoxins *D012710 Serum Albumin, Bovine D000941 Antigens Appl Environ Microbiol 1984;47(3):526 DLJ CCR CCR M0122311 aflatoxin Q2a-bovine serum albumin C0621143 0 T152316 aflatoxin Q2a-bovine serum albumin T152315 AFQ2a-bovine serum albumin T152314 AFQ2a-BSA C002511 chaetocin 1973 01 01 1982 01 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *INDOLES (73-82) *PIPERAZINES (73-82) DISULFIDES (73-76) D010879 Piperazines Chem Ber 105(2):625;1972 NLM NBM NLM M0043141 chaetocin C0055248 28097-03-2 T073144 chaetocin C002513 N-(2-chloro-1-naphthylidene)-3-amino-2,6-lutidine 1973 01 01 1991 06 03 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PIPERIDINES (73-79) *PYRIDINES (73-82) *D009281 Naphthalenes J Reprod Fertil 31(3):383;1972 NLM LBG NLM M0043143 N-(2-chloro-1-naphthylidene)-3-amino-2,6-lutidine C0601487 38641-70-2 T073146 N-(2-chloro-1-naphthylidene)-3-amino-2,6-lutidine C002515 5 alpha-cholest-8(14)-en-7-one 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CHOLESTENES (73-75) KETOSTEROIDS (73-75) *D002783 Cholestenones J Chem Soc (Perkin I)21:2771;1972 NLM NLM M0043145 5 alpha-cholest-8(14)-en-7-one C0601489 0 T073148 5 alpha-cholest-8(14)-en-7-one C002519 dimethialium propyldisulfide 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *DISULFIDES (73-76) AMIDES (73-74) *D011743 Pyrimidines Jap Circulation J 36(9):935;1972 NLM NLM M0043146 dimethialium propyldisulfide C0601490 7244-66-8 T073149 dimethialium propyldisulfide C002520 3-dimethylaminopropyldiphenylphosphine 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 CNS depressant; structure 0 *PHOSPHINES (73-76) PROPYLAMINES (73-82) *D009943 Organophosphorus Compounds Biochem Pharmacol 21(24):3235;1972 NLM VSR NLM M0043147 3-dimethylaminopropyldiphenylphosphine C0601491 961-04-6 T073150 3-dimethylaminopropyldiphenylphosphine C002574 dopastin 1973 01 01 2000 10 09 1998 1999 2000 2000A 2001 2002 mushroom extract 1 NITROSAMINES (73-82) *D000577 Amides D004299 Dopamine beta-Hydroxylase Q000037 antagonists ; inhibitors J Antibiotics 25(8):497;1972 NLM TWD TWD M0043232 dopastin C0601517 N-(2-(hydroxynitrosoamino))-3-methylbutyl-2- 37134-80-8 T109 Organic Chemical T121 Pharmacologic Substance T073235 dopastin T073234 butenamide C002529 1 alpha-hydroxycorticosterone 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 8 *HYDROCORTISONE (73-75) D003345 Corticosterone *Q000031 analogs ; derivatives Comp Biochem Physiol 44B(1):179;1973 J Chem Soc Perkins I 22:2371;1975 Steroids 31(4):573;1978 NLM NLM M0043166 1 alpha-hydroxycorticosterone C0043667 1 alpha,11 beta,21-trihydroxypregn-4-ene-3,20- dione 10163-49-2 T073169 1 alpha-hydroxycorticosterone C406238 FAC1 protein 2000 04 07 2000 10 10 2000 2000A 2000B 2000C 2000D 2001 2002 FAC1 - Fetal Alz-50-Reactive Clone 1; located both in nucleus and cytoplasm of cells of the developing cortex; amino acid sequence given in both sources; GenBank AB032251(BPTF) and U05237(FAC1); RefSeq NM_004459 13 *D009419 Nerve Tissue Proteins *D014157 Transcription Factors Dev Neurosci 1995;17(1):20-37 Genomics 2000 Jan 1;63(1):35-9 THA WXM WXM M0360248 FAC1 protein C0300134 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T279765 FAC1 protein T411441 BPTF protein 2000 04 07 T411442 bromodomain PHD finger transcription factor 2000 04 07 T279764 FAC1 gene product T426062 FALZ protein 2000 10 06 T426061 fetal Alzheimer antigen 2000 10 06 C067357 protein Kau, Fab fragment 1991 03 18 2001 01 29 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 human monoclonal cold agglutinin (IgM(K); amino acid sequence given in first source; RN given refers to the light chain 2 *D000373 Agglutinins *D007075 Immunoglobulin M *D007140 Immunoglobulins, Fab J Biol Chem 1991;266(5):2836 RLS CCR CCR M0184646 protein Kau, Fab fragment C0378790 136542-96-6 136542-95-5 (.mu.-chain) M0184646 M0325064 T214651 protein Kau, Fab fragment T214650 Kau protein, Fab fragment M0325064 protein Kau, Fab fragment, .mu.-chain C0958501 136542-95-5 M0184646 M0325064 T355064 protein Kau, Fab fragment, .mu.-chain 1999 08 18 C002538 methylene dimethanesulfonate 1974 01 01 1982 11 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 9 *METHANESULFONATES (74-75) *METHYL METHANESULFONATE/analogs (75-80) D008741 Methyl Methanesulfonate *Q000031 analogs ; derivatives D013091 Spermatogenesis Q000187 drug effects Br Med Bull 26(1):83;1970 Chem Biol Interact 11(3):163;1975 Chem Biol Interact 14(1-2):93;1976 NLM VSR NLM M0043187 methylene dimethanesulfonate C0066350 156-72-9 T073190 methylene dimethanesulfonate C002543 alumicrocin 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 ferrichrome analog 0 *HYDROXAMIC ACIDS (73-76) *PEPTIDES, CYCLIC (73-75) D005291 Ferrichrome *Q000031 analogs ; derivatives J Biol Chem 248(3):924;1973 NLM RLS NLM M0043191 alumicrocin C0601503 39028-06-3 T073194 alumicrocin C002544 alumichrysin 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 ferrichrome analog 0 *PEPTIDES, CYCLIC (73-75) HYDROXAMIC ACIDS (73-76) D005291 Ferrichrome *Q000031 analogs ; derivatives J Biol Chem 248(3):924;1973 NLM RLS NLM M0043192 alumichrysin C0601504 39028-07-4 T073195 alumichrysin C002548 asebotin 1973 01 01 1978 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *GLYCOSIDES (73-78) PLANT EXTRACTS (73-76) *D005960 Glucosides J Pharm Soc Jap 92(9):1173;1972 NLM NLM M0043201 asebotin C0601507 11075-15-3 T073204 asebotin C071768 picrasinoside H 1991 12 24 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 from Picrasam ailanthoides; structure given in first source 1 D005900 Glaucarubin *Q000031 analogs ; derivatives J Nat Prod 1991;54(3):844 RLS TPW M0194812 picrasinoside H C0648685 Picras-2-en-1-one, 13-(acetyloxy)-16-(beta-D-glucopyranosyloxy)-2-methoxy-11,12-(methylenebis(oxy))-, (11alpha,12beta,16alpha)- 135638-54-9 T224817 picrasinoside H C004681 acetylstrophanthidin 1970 01 01 2001 01 29 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 85 *CARDANOLIDES (70-75) *STROPHANTHIDIN (75-77) D013327 Strophanthidin *Q000031 analogs ; derivatives Circ Res 41(5):622;1977 New Engl J Med 296(6):301;1977 NLM TWD TWD M0045817 acetylstrophanthidin C0050541 3 beta,5,14,19-tetrahydroxy-5 beta-card-20(22)- enolide 19-acetate 60-38-8 T075820 acetylstrophanthidin T075819 acetylstrophantindin C002553 caroxin D 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 fluorocarbon liquid C10F2202 1 *HYDROCARBONS, HALOGENATED (73-74) FLUORINE (73-74) *D005466 Fluorocarbons Anesthesiology 38(2):134;1973 NLM NLM M0043206 caroxin D C0054821 23228-90-2 T073209 caroxin D C002554 cepevit-K 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 hemostatic combination drug consisting of vitamin C, hesperydine methyl chalcone, esculin, methyl rutin, ; vitamin K 0 *PROPIOPHENONES (73-75) *RUTIN (73-75) *D001205 Ascorbic Acid *D014812 Vitamin K D002599 Chalcone *Q000031 analogs ; derivatives D004338 Drug Combinations D012431 Rutin *Q000031 analogs ; derivatives Pol Tyg Lek 27(47):1862;1972 NLM RLS NLM M0043207 cepevit-K C0601508 L-Ascorbic acid, mixt. with 3-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one, (E)-1-(4-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-2-hydroxy-6-methoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-2-propen-1-one, 6-(beta-D-glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one and vitamin K 75919-67-4 T073210 cepevit-K C120157 p53-binding protein 3 1999 09 23 2000 10 10 1999 2000 2000A 2000B 2000C 2000D 2000E 2001 2002 topors - TOPOisomerase I-binding RS protein; a RING zinc finger/arginine-serine (RS) protein that interacts with topoisomerase I; amino acid sequence in both sources; GenBank AF098300(topors) and U82939(p53BP3); RefSeq NM_005802 3 *D002352 Carrier Proteins *D004268 DNA-Binding Proteins *D009687 Nuclear Proteins D004264 DNA Topoisomerases, Type I D014157 Transcription Factors D016159 Protein p53 D016335 Zinc Fingers Gene 1999 Jul 22;235(1-2):93-101 Nucleic Acids Res 1999 Jun 15;27(12):2538-44 CCR WXM WXM M0332237 p53-binding protein 3 C0893481 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance M0332237 M0333529 T365400 p53-binding protein 3 T363132 topors T426056 TP53BPL 2000 10 06 T426055 tumor protein p53-binding protein 2000 10 06 M0333529 p53BP C0893482 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance M0332237 M0333529 T365401 p53BP C002557 cholesterol 7 beta-hydroperoxide 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *CHOLESTEROL (73-75) *PEROXIDES (73-76) D002784 Cholesterol *Q000031 analogs ; derivatives J Org Chem 38(1):119;1972 NLM NLM M0043209 cholesterol 7 beta-hydroperoxide C0601509 35455-44-8 T073212 cholesterol 7 beta-hydroperoxide C002558 chromomembrin A 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 MEMBRANES (73-76) *D002864 Chromogranins Biochem J 129(1):187;1972 NLM NLM M0043210 chromomembrin A C0601510 0 T073213 chromomembrin A C002559 cryomycin 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 antibiotic isolated from Streptomyces griseus, subsp psychrophilus produced only at low temperature 0 *D000900 Antibiotics J Antibiotics 25(11):653;1972 NLM NLM M0043211 cryomycin C0056544 37306-12-0 T073214 cryomycin C004686 clocortolone 1973 01 01 2001 01 29 1998 1999 2000 2001 2001A 2002 RN given refers to (6alpha,11beta,16alpha)-isomer; structure 0 *FLUOCORTOLONE/analogs (79-80) *PREGNADIENEDIOLS (74-79) *PREGNADIENES (73-74) PREGNENEDIONES (75-79) D005448 Fluocortolone *Q000031 analogs ; derivatives NLM TWD TWD M0045819 clocortolone C0055899 9-chloro-6 alpha-fluoro-11 beta,21-dihydroxy- 16 alpha-methylpregnadiene-3,20-dione 21-acetate 4828-27-7 4258-85-9 (acetate) M0045819 M0308672 T075822 clocortolone Merck Index, 9th ed, p. 304, #2337 M0308672 clocortolone acetate C0770567 4258-85-9 M0045819 M0308672 T338672 clocortolone acetate 1999 08 18 C002568 3-diazopyrazole-4-carboxamide 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *AZO CPDS (73-79) DIAZONIUM COMPOUNDS (73-82) FORMAMIDES (75-76) *D011720 Pyrazoles Biochem Pharmacol 21(15):2141;1972 NLM VSR NLM M0043222 3-diazopyrazole-4-carboxamide C0601512 38658-38-7 T073225 3-diazopyrazole-4-carboxamide C002573 4,4'-dinitrobiphenyl 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 NITRO CPDS (73-76) *D001713 Biphenyl Compounds Am Occup Hyg 15(2):203;1972 NLM NLM M0043230 4,4'-dinitrobiphenyl C0601515 1528-74-1 T073233 4,4'-dinitrobiphenyl C002588 iron(II)-5-pyridylbenzodiazepin-2-one 1973 01 01 1997 07 15 1998 1999 2000 2001 2002 used for determination of uric acid in blood 0 *BENZAZEPINES (73-74) PYRIDINES (73-82) *D001570 Benzodiazepinones Clin Chem 19(1):67;1973 NLM NNS BVL M0043253 iron(II)-5-pyridylbenzodiazepin-2-one C0601525 0 T073256 iron(II)-5-pyridylbenzodiazepin-2-one C002594 3-methyl-4-nitropyridine 1-oxide 1973 01 01 1977 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CYCLIC N-OXIDES (73-76) *PYRIDINES (73-77) *D010847 Picolines Mutation Res 17(1):127;1972 NLM NLM M0043264 3-methyl-4-nitropyridine 1-oxide C0601526 1074-98-2 T073267 3-methyl-4-nitropyridine 1-oxide C002677 biotinyl-4-nitrophenyl ester 1972 01 01 2001 01 26 1997 1998 1999 2000 2001 2001A 2002 4 *BIOTIN (72-76) NITROPHENOLS (72-76) D001710 Biotin *Q000031 analogs ; derivatives Proc Nat Acad Sci USA 68(10):2604;1971 NLM TWD TWD M0043385 biotinyl-4-nitrophenyl ester C0053655 33755-53-2 T073388 biotinyl-4-nitrophenyl ester T073387 biotin-p-nitrophenyl ester C002606 neo-cholex powder 1973 01 01 1986 08 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination drug used as gallbladder contracting agent; contains vegetable oil, sugar, milk fat, lecithin, casein, cocoa 1 *OILS (73-86) *D002241 Carbohydrates *D002364 Caseins *D010938 Plant Oils D004338 Drug Combinations Jpn J Clin Radiol 17(9):502;1972 NLM THA NLM M0043277 neo-cholex powder C0068496 0 T073280 neo-cholex powder C002609 9-phenyl-5:6-benzoisoalloxazine 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PIGMENTS (73-76) *D005415 Flavins Perspect Biol Med 16(2):270;1973 NLM NLM M0043280 9-phenyl-5:6-benzoisoalloxazine C0601532 0 T073283 9-phenyl-5:6-benzoisoalloxazine C005330 gilutensin 1973 01 01 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 CNS stimulant, anti-hypotensive agent; RN given refers to parent cpd; structure 0 *BUTYLAMINES (73-82) ALKENES (73-75) *D001597 Benzylidene Compounds D007022 Hypotension Q000188 drug therapy NLM TWD TWD M0046813 gilutensin C0602182 2-ethyl-3,3-diphenylpropen-2-ylamine 341-00-4 1146-95-8 (HCl) M0046813 M0309026 T076816 gilutensin Merck Index, 8th ed, p. 489 M0309026 gilutensin hydrochloride C0951365 1146-95-8 M0046813 M0309026 T339026 gilutensin hydrochloride 1999 08 18 C114345 coniferyl aldehyde dehydrogenase 1998 09 21 2001 01 29 1998 1999 2000 2000A 2001 2001A 2002 catalyzes NAD+-dependent oxidation of coniferyl aldehyde to ferulic acid; isolated from Pseudomonas; amino acid sequence in first source; GenBank AJ006231 1 *D000445 Aldehyde Oxidoreductases J Bacteriol 1998 Sep;180(17):4387-91 THA CCR CCR M0294930 coniferyl aldehyde dehydrogenase C0757216 EC 1.2.1.- T324935 coniferyl aldehyde dehydrogenase T324934 calB gene product T324933 CALDH enzyme C002618 polyxylan sulfonic acid ester 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *POLYSACCHARIDES (73-75) SULFONIC ACIDS (73-76) *D014990 Xylans Angiologia 25(1):43;1972 NLM NLM M0043297 polyxylan sulfonic acid ester C0601535 0 T073300 polyxylan sulfonic acid ester C002662 prostaglandin-ICI 74205 1973 01 01 2000 07 31 2001 2002 has two more carbons on lower side chain than PGF2alpha; RN given refers to (3S*)-isomer; structure 0 *PROSTAGLANDINS (73-78) PGF (78-79) *D011461 Prostaglandins F, Synthetic Prostaglandins 2(5):375;1972 NLM CCR sjn M0043351 prostaglandin-ICI 74205 C0601561 36950-85-3 T111 Eicosanoid T121 Pharmacologic Substance 37497-26-0 ((3R*)-isomer) M0043351 M0308016 T073354 prostaglandin-ICI 74205 T073351 ICI 74205 T073353 PG-ICI 74205 T073352 PG-ICI 742-5 M0308016 prostaglandin-ICI 74205, (3R*)-isomer C0894278 37497-26-0 T111 Eicosanoid T121 Pharmacologic Substance M0043351 M0308016 T338016 prostaglandin-ICI 74205, (3R*)-isomer 1999 08 18 C411123 6-oxocampestanol 2000 07 25 2000 2001 2002 isolated from Catharanthus roseus; structure in first source 1 *D010840 Phytosterols Phytochemistry 2000 Mar;53(5):549-53 THA THA M0366571 6-oxocampestanol C0915872 0 T110 Steroid T419889 6-oxocampestanol 2000 07 25 C005332 N-phenylethanolamine 1973 01 01 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 13 ANILINE COMPOUNDS (73-76) *D004983 Ethanolamines Int Rev Neurobiol 19:211;1976 NLM TWD TWD M0046819 N-phenylethanolamine C0068266 122-98-5 T076822 N-phenylethanolamine T076821 2-anilinoethanol C002627 kaurene 1974 01 01 1983 08 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 11 *D004224 Diterpenes Yakugaku Zasshi 92(11):1405;1972 NLM ACS NLM M0043306 kaurene C0083126 34424-57-2 T073309 kaurene C002628 octadecyldihydroxyacetone phosphate 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ACETONE (73-75) *TRIOSES (73-75) ETHERS (74-76) ORGANOPHOSPHORUS COMPOUNDS (73-75) D004099 Dihydroxyacetone Phosphate *Q000031 analogs ; derivatives J Pharm Sci 62(2):320;1973 NLM RLS NLM M0043307 octadecyldihydroxyacetone phosphate C0601538 2-Propanone, 1-(octadecyl-1-14C-oxy)-3-(phosphonooxy)- 40166-27-6 T073310 octadecyldihydroxyacetone phosphate C002631 N-(3,5-dimethyl-4-isoxazolylmethyl)phthalimide 1973 01 01 1982 02 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *IMIDES (73-75) *PHTHALIC ACID (73-75) ISOXAZOLES (75-82) OXAZOLES (73-75) *D010797 Phthalimides Acta Endocrinol 72(3):604;1973 Arch Anat Microsc Morphol Exp 64(1):27;1975 Mol Cell Endocrinol 1979;15(2):91 NLM NBM NLM M0043316 N-(3,5-dimethyl-4-isoxazolylmethyl)phthalimide C0067484 2-((3,5-dimethyl-4-isoxazolyl)methyl)-1H-isoindole-1,3(2H)-dione 39962-28-2 T073319 N-(3,5-dimethyl-4-isoxazolylmethyl)phthalimide C002647 inositol 1-phosphate 1973 01 01 2001 04 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 116 *INOSITOL (73-75) *ORGANOPHOSPHORUS COMPOUNDS (73-75) INOSITOL/*analogs (76-85) SUGAR PHOSPHATES (74-82) *D007295 Inositol Phosphates J Am Chem Soc 97(23):6810;1975 Nature (New Biol) 240(104):258;1972 NLM CCR CCR M0043337 inositol 1-phosphate C0063574 D-myo-Inositol, 1-(dihydrogen phosphate) 15421-51-9 T073340 inositol 1-phosphate T073338 inositol 1-monophosphate T073339 myoinositol 1-phosphate C101916 SBS-g-VP copolymer 1996 11 25 2001 04 04 1998 1999 2000 2001 2001A 2002 4-vinylpyridine grafted to SBS polymer via radiation-induced copolymerization 1 *D011137 Polystyrenes *D011725 Pyridines J Biomed Mater Res 1996 Jun;31(2):281-6 THA TWD TWD M0267033 SBS-g-VP copolymer C0530793 0 T297038 SBS-g-VP copolymer T297037 SBS-g-(4-vinylpyridine) copolymer C101917 N,N-(2,3-dihydroxybuta-1,4-diyl)valine 1996 11 26 2001 04 04 1998 1999 2000 2001 2001A 2002 a ring-closed pyrrolidine-structured compound 1 *D011759 Pyrrolidines D014633 Valine *Q000031 analogs ; derivatives Chem Biol Interact 1996 Sep 6;101(3):193-205 PML TWD TWD M0267035 N,N-(2,3-dihydroxybuta-1,4-diyl)valine C0530795 0 T297040 N,N-(2,3-dihydroxybuta-1,4-diyl)valine T297039 N,N-PYRV C411124 6-deoxacastasterone 2000 07 25 2000 2001 2002 isolated from Catharanthus roseus; structure in first source 1 *D010840 Phytosterols Phytochemistry 2000 Mar;53(5):549-53 THA THA M0366572 6-deoxacastasterone C0915873 0 T110 Steroid T419890 6-deoxacastasterone 2000 07 25 C101918 N-(2,3,4-trihydroxybutyl)valine 1996 11 26 2001 04 04 1998 1999 2000 2001 2001A 2002 3 D014633 Valine *Q000031 analogs ; derivatives Chem Biol Interact 1996 Sep 6;101(3):193-205 PML TWD TWD M0267037 N-(2,3,4-trihydroxybutyl)valine C0530797 0 T297042 N-(2,3,4-trihydroxybutyl)valine T297041 N-THBV C002651 18-hydroxytetrahydrodeoxycorticosterone 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *HYDROXYCORTICOSTEROIDS (73-75) *PREGNANES (73-75) D015070 18-Hydroxydesoxycorticosterone *Q000031 analogs ; derivatives Rec Prog Horm Res 28:2871;1972 NLM NLM M0043339 18-hydroxytetrahydrodeoxycorticosterone C0601554 3 alpha,18,21-trihydroxy-5 beta-pregnan-20-one 31935-07-6 T073342 18-hydroxytetrahydrodeoxycorticosterone C002652 5-propyluracil 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *URACIL (73-75) PROPANE (73-75) D014498 Uracil *Q000031 analogs ; derivatives Acta Biochim Pol 19(3):207;1972 NLM NLM M0043340 5-propyluracil C0601555 19030-75-2 T073343 5-propyluracil C002653 5-isopropyluracil 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *URACIL (73-75) PROPANE (73-76) D014498 Uracil *Q000031 analogs ; derivatives Acta Biochim Pol 19(3):207;1972 NLM NLM M0043341 5-isopropyluracil C0601556 17432-95-0 T073344 5-isopropyluracil C002654 5,6-dihydro-5,6-cyclobutanyluracil 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *URACIL (73-75) CYCLOBUTANES (73-76) D014498 Uracil *Q000031 analogs ; derivatives Acta Biochim Pol 19(3):207;1972 NLM NLM M0043342 5,6-dihydro-5,6-cyclobutanyluracil C0601557 0 T073345 5,6-dihydro-5,6-cyclobutanyluracil C106276 TBC 11251 1997 06 24 2001 04 04 1997 1998 1999 2000 2001 2001A 2002 endothelin A receptor antagonist; structure in first source 10 *D007555 Isoxazoles *D013876 Thiophenes D017466 Receptors, Endothelin Q000037 antagonists ; inhibitors J Med Chem 1997 May 23;40(11):1690-7 THA CCR CCR M0276993 TBC 11251 C0539625 0 T306998 TBC 11251 T306996 TBC-11251 T306997 TBC11251 C101921 phenoxymethylpenicillin amidohydrolase 1996 11 26 2001 04 04 1997 1998 1999 2000 2001 2001A 2002 isolated from Penicillium chrysogenes; hydrolyses phenoxymethylpenicillin to 6-aminopenicillanic acid (6-APA) 1 *D010399 Penicillin Amidase FEBS Lett 1996 Sep 23;394(1):31-3 PML TWD TWD M0267041 phenoxymethylpenicillin amidohydrolase C0530801 EC 3.5.1.- T297046 phenoxymethylpenicillin amidohydrolase T297045 PMP amidase C002671 3-beta-acetoxy-beta-norandrost-5-en-17-one 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 NORANDROSTANES (73-82) NORSTEROIDS (73-75) *D000737 Androstenols J Org Chem 38(2):289;1973 NLM VSR NLM M0043374 3-beta-acetoxy-beta-norandrost-5-en-17-one C0601569 0 T073377 3-beta-acetoxy-beta-norandrost-5-en-17-one C002673 digalactosyl ceramide 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CERAMIDES (73-75) GALACTOSE/analogs (75-76) *D006028 Glycosphingolipids Arch Surg 106(2):231;1973 NLM NLM M0043375 digalactosyl ceramide C0601570 0 T073378 digalactosyl ceramide C002674 methylsulfomethylate 1973 01 01 1983 08 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 Russian Drug; structure 1 *CHOLINESTERASE INHIBITORS (73-79) SULFIDES (73-76) *D009946 Organothiophosphorus Compounds Biokhimiia 39(6):1163;1974 Biull Eksp Biol Med 86(10):441;1978 Dokl Akad Nauk SSSR 234(1):242;1977 Dokl Akad Nauk SSSR 245(2):477;1979 Farmakol Toksikol 35(5):571;1972 Fiziol Zh SSSR 63(12):1638;1977 NLM DLJ NLM M0043378 methylsulfomethylate C0066436 2562-54-1 M0043378 M0043377 M0043378 M0043376 T073381 methylsulfomethylate M0043377 O-ethyl S-(beta-ethylthioethyl)(methyl)thiophosphonate methosulfate C0133476 M0043378 M0043377 T073380 O-ethyl S-(beta-ethylthioethyl)(methyl)thiophosphonate methosulfate M0043376 GD-42 C0118942 M0043378 M0043376 T073379 GD-42 C105804 transglutaminase 1 1997 05 28 2001 09 06 2002 TRANSGLUTAMINASE 1 (TGM1 or TGK) is a membrane-associated enzyme involved in the formation of the cornified cell envelope of the EPIDERMIS; Mutations in the human gene (14q11) cause autosomal recessive lamellar ICHTHYOSIS; Distinguish from GAMMA-GLUTAMYLTRANSPEPTIDASE involved with glutathione metabolism and other protein cross-linking transglutaminases. 65 *D011503 Transglutaminases Arch Dermatol Res 1997 Jan;289(2):116-9 BVL ssb sjn M0275883 transglutaminase 1 C0538672 EC 2.3.2.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T305887 transglutaminase 1 T433948 epidermal type I transglutaminase 2001 01 23 T433947 keratinocyte transglutaminase K 2001 01 23 T305886 TGM1 gene product T433950 transglutaminase i 2001 01 23 T305888 transglutaminase K T433952 transglutaminase TGM1 2001 01 23 T433951 transglutaminase Type I 2001 01 23 T433949 transglutaminase1 2001 01 23 C002676 ethefil 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 Russian; structure 0 DICARBOXYLIC ACIDS (73-76) FORMAMIDES (75-76) *D007093 Imidazoles Farmakol Toksikol 35(5):533;1972 NLM NLM M0043383 ethefil C0601571 N,N'-diethylimidazole-4,5-dicarboxamide 65-21-4 T073386 ethefil Negwer #987 C002678 2,4,6-tris(trifluoromethyl)-sym-triazine 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 FLUORINE (73-74) HYDROCARBONS, FLUORINATED (74-76) HYDROCARBONS, HALOGENATED (73-74) *D014227 Triazines Am Ind Hyg Assoc J 33(6):382;1972 NLM NLM M0043386 2,4,6-tris(trifluoromethyl)-sym-triazine C0601572 2,4,6-tris(trifluoromethyl)-s-triazine 368-66-1 T073389 2,4,6-tris(trifluoromethyl)-sym-triazine C002699 neoantimycin 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *D000900 Antibiotics J Chem Soc 9(0):1235;1972 NLM NLM M0043407 neoantimycin C0601576 22862-63-1 T073410 neoantimycin C002703 neoproteolipid-W 1972 01 01 1982 10 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 isolated from Walker carcinoma 256 0 *D008074 Lipoproteins D009363 Neoplasm Proteins Res Commun Chem Pathol Pharmacol 3(1):165;1972 NLM VSR NLM M0043412 neoproteolipid-W C0601577 0 T073415 neoproteolipid-W C002706 Nephrolith 1971 01 01 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D007666 Khellin *D010936 Plant Extracts *D013449 Sulfonamides D004338 Drug Combinations Urol Nephrol 70(6):429;1977 NLM NLM M0043414 Nephrolith C0068552 Nephrolith 78308-35-7 T073417 Nephrolith C076067 common plant regulatory factor 2 1992 09 10 2001 06 08 1999 2000 2001 2001A 2002 bZIP domain amino acid sequence given in first source; participates in the light-mediated activation of the light-responsive chalcone synthase gene in parsley 5 *D004268 DNA-Binding Proteins *D010940 Plant Proteins D014157 Transcription Factors D016350 Leucine Zippers Plant Cell 1992 May;4(5):525-37 BXB TWD TWD M0204719 common plant regulatory factor 2 C0653137 0 T234724 common plant regulatory factor 2 T234723 CPRF-2 C002716 2-nitrilophenoxypropanolamine 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 NITRILES (74-76) *D011412 Propanolamines Eur J Pharmacol 16(1):14;1971 NLM NLM M0043424 2-nitrilophenoxypropanolamine C0601582 Benzonitrile, 2-(3-amino-2-hydroxypropoxy)-, monohydrochloride 33825-81-9 T073427 2-nitrilophenoxypropanolamine C002728 4-nitrophenyl ethyl phosphonate 1973 01 01 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 *NITROBENZENES (73-82) PHOSPHONIC ACIDS (73-75) *D009943 Organophosphorus Compounds NLM TWD TWD M0043433 4-nitrophenyl ethyl phosphonate C0601587 32357-11-2 T073436 4-nitrophenyl ethyl phosphonate T073435 p-nitrophenyl ethyl phosphonate C002726 (4-nitrophenoxy)acetic acid 1971 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *NITROPHENOLS (71-75) NITRO COMPOUNDS (75-76) *D006016 Glycolates NLM NLM M0043431 (4-nitrophenoxy)acetic acid C0601585 1798-11-4 T073434 (4-nitrophenoxy)acetic acid C002741 N-nitrosomorpholine 1972 01 01 1984 07 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 220 *MORPHOLINES (72-81) NITROSO COMPOUNDS (72-76) *D009602 Nitrosamines Arch Int Physiol Biochim 86(2):470;1978 Arch Toxicol 1979;42(4):225 Cancer 42(2):462;1978 Cancer Res 1980;40(1):119 Cancer Res 1980;40(2):459 Chem Biol Interact 11(5):413;1975 Chem Biol Interact 20:341;1978 Food Cosmet Toxicol 13(2):239;1975 Fortschr Med 95:2629;1977 J Anal Chem 49(8):715A;1977 J Ultrastruct Res 1980;70(1):82 Mutat Res 1979;64(6):415 Mutat Res 31(3):153;1975 Mutat Res 46(4):265;1977 Scan Electron Microsc 1979;3:161 Verh Dtsch Ges Pathol 62:467;1978 Verh Dtsch Ges Pathol 62:495;1978 Z Krebsforsch 77(3):189;1972 Z Krebsforsch 86(1):95;1976 NLM MEG NLM M0043451 N-nitrosomorpholine C0068232 59-89-2 D002273 Carcinogens D009153 Mutagens T073454 N-nitrosomorpholine C005415 ovobrene 1973 01 01 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *ESTROGENS (74-75) BROMINE (73-74) PHENYLACETATES (73-74) *D013267 Stilbenes D004969 Estrogens, Synthetic NLM TWD TWD M0046948 ovobrene C0602212 Phenol, 4,4'-(bromophenylethenylidene)bis-, diacetate 6192-24-1 T076951 ovobrene T076950 1,1-bis(p-acetoxyphenyl)-2-phenyl-2-bromoethylene C002745 nitroxide maleimide 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 *CYCLIC N-OXIDES (74-76) *D008301 Maleimides NLM NLM M0043461 nitroxide maleimide C0068880 0 T073464 nitroxide maleimide C111313 4-(2-((2-thienyl)phenylmethoxy)ethyl)-1-(3-phenylpropyl)piperidine 1998 04 10 2000 12 15 1998 1999 2000 2001 2001A 2002 ligand for dopamine transporter; structure in first source 1 *D001559 Benzhydryl Compounds *D010880 Piperidines D008024 Ligands J Med Chem 1998 Feb 26;41(5):699-705 THA TWD TWD M0288284 4-(2-((2-thienyl)phenylmethoxy)ethyl)-1-(3-phenylpropyl)piperidine C0672863 0 T109 Organic Chemical T121 Pharmacologic Substance T318289 4-(2-((2-thienyl)phenylmethoxy)ethyl)-1-(3-phenylpropyl)piperidine T318288 4-TPMEPP-piperidine C002748 noradrenalone 1972 01 01 1990 11 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure; RN given refers to parent cpd 1 *CATECHOLAMINES (72-75) KETONES (72-75) D009638 Norepinephrine *Q000031 analogs ; derivatives Arch Int Pharmacodyn Ther 192(2):279;1973 NLM WMM NLM M0043469 noradrenalone C0068956 499-61-6 5090-29-9 (HCl) M0043469 M0043467 M0043469 M0043468 M0043469 M0308039 T073472 noradrenalone M0043467 aminoacetocatechol C0102962 M0043469 M0043467 T073470 aminoacetocatechol M0043468 catechol aminoketone C0108580 M0043469 M0043468 T073471 catechol aminoketone M0308039 HCl of noradrenalone C0894295 5090-29-9 M0043469 M0308039 T338039 HCl of noradrenalone 1999 08 18 C002746 Noracycline 1971 01 01 2000 12 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 contains lynestrenol ; mestranol 23 *CONTRACEPTIVES, ORAL (71-72) DRUG COMBINATIONS (72-76) *D008234 Lynestrenol *D008656 Mestranol D003277 Contraceptives, Oral, Combined J Steroid Biochem 9(8):811;1978 NLM CCR CCR M0043465 Noracycline C0068952 8015-14-3 T110 Steroid T121 Pharmacologic Substance M0043465 M0043462 M0043465 M0043464 T073468 Noracycline T073466 Noracyclin M0043462 Lyndiol C0950179 T110 Steroid T121 Pharmacologic Substance M0043465 M0043462 T073465 Lyndiol M0043464 Ovanon C0950180 T110 Steroid T121 Pharmacologic Substance M0043465 M0043464 T073467 Ovanon C005224 meglumine acetrizoate 1972 01 01 2000 12 15 1997 1998 1999 2000 2001 2001A 2002 0 *AMINO SUGARS (72-76) *IODOBENZOATES (74-76) SORBITOL (72-76) *D003974 Diatrizoate Meglumine NLM CCR CCR M0046620 meglumine acetrizoate C0065881 22154-43-4 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0046620 M0046617 M0046620 M0046619 T076623 meglumine acetrizoate Negwer 821a T076621 methylglucamine triiodobenzoic acid M0046617 Fortombrine C0118157 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0046620 M0046617 T076620 Fortombrine M0046619 Vasurix C0148243 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0046620 M0046619 T076622 Vasurix C028121 N-benzyloxycarbonyltyrosine-4-nitrophenyl ester 1981 02 05 2000 12 15 1998 1999 2000 2001 2001A 2002 RN given refers to (L)-isomer 4 D014443 Tyrosine *Q000031 analogs ; derivatives Biochem Biophys Acta 412(2):273;1975 Biochem Soc Trans 1980;8(5):583 RLS WXM WXM M0090814 N-benzyloxycarbonyltyrosine-4-nitrophenyl ester C0067850 L-Tyrosine, N-((phenylmethoxy)carbonyl)-, 4-nitrophenyl ester 3556-56-7 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid 24256-84-6 ((D)-isomer) M0090814 M0317627 M0090814 M0090812 T120817 N-benzyloxycarbonyltyrosine-4-nitrophenyl ester T120813 BOCTNP T120814 CBZTNP T120816 N-carbobenzoxy-L-tyrosine p-nitrophenyl ester M0317627 N-benzyloxycarbonyltyrosine-4-nitrophenyl ester, (D)-isomer C0970266 24256-84-6 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0090814 M0317627 T347627 N-benzyloxycarbonyltyrosine-4-nitrophenyl ester, (D)-isomer 1999 08 18 M0090812 N-alpha-carbobenzoxy-tyrosine-p-nitrophenyl ester C0130835 0 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0090814 M0090812 T120815 N-alpha-carbobenzoxy-tyrosine-p-nitrophenyl ester C005436 phosphohistidine 1973 01 01 2001 01 29 1998 1999 2000 2001 2001A 2002 RN given refers to N-phosphono-L-histidine 60 *HISTIDINE (73-75) ORGANOPHOSPHORUS COMPOUNDS (74-76) D006639 Histidine *Q000031 analogs ; derivatives Biochim Biophys Acta 526(1):147;1978 NLM TWD TWD M0046985 phosphohistidine C0070872 4936-08-7 T076988 phosphohistidine T076987 3-phosphohistidine C024918 benzyloxycarbonylphenylalanylalanine diazomethyl ketone 1980 06 19 2000 12 15 1997 1998 1999 2000 2001 2001A 2002 selective inhibitor of thiol proteinases 27 D003978 Diazomethane *Q000031 analogs ; derivatives Biochem J 1980;186(2):385 MJC CCR CCR M0083686 benzyloxycarbonylphenylalanylalanine diazomethyl ketone C0053318 0 T109 Organic Chemical T121 Pharmacologic Substance D015853 Cysteine Proteinase Inhibitors T113689 benzyloxycarbonylphenylalanylalanine diazomethyl ketone T113685 N-CBZ-phenylalanyl-alanine-diazomethyl ketone T113687 Z-Phe-Ala-CHN2 T113688 ZDAP cpd T113686 Z-FA-DMK C002767 oidiomycin 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *D000902 Antibiotics, Antifungal Int J Lepr 39(2):556;1971 NLM NLM M0043493 oidiomycin C0069386 Oidiomycin 78355-47-2 T073496 oidiomycin C002779 Otipax 1971 01 01 1982 09 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains above 2 cpds 1 *D000632 Aminopyrine *D008012 Lidocaine D004338 Drug Combinations NLM VSR NLM M0043506 Otipax C0243222 0 T073509 Otipax C022649 sphingosine 1-phosphate lyase (aldolase) 1975 01 01 2001 01 29 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 9 SPHINGOSINE (75-82) *D000446 Aldehyde-Lyases Chem Phys Lipids 13(4):382;1974 NLM CCR CCR M0078993 sphingosine 1-phosphate lyase (aldolase) C0143251 EC 4.1.2.- T108996 sphingosine 1-phosphate lyase (aldolase) T108994 SPH-1-lyase T108995 sphingosine-1-phosphate lyase C002781 ovalicin 1972 01 01 1982 07 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 sesquiterpene isolated from culture filtrate of fungus Pseudorotium ovalis; shows antitumor activity; structure 10 *ETHERS, CYCLIC (72-75) CYCLOHEXANONES (75-82) *D012717 Sesquiterpenes Agents Actions 4(5):357;1974 Helv Chim Acta 51:1395;1968 J Am Chem Soc 97(5):1282;1975 J Am Chem Soc 98(5):1183;1976 Planta Med 34(3):231;1978 NLM VSR NLM M0043509 ovalicin C0069690 19683-98-8 T073512 ovalicin C002783 Ovaribran 1972 01 01 1993 05 26 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains conjugated estrogens ; Adumbran; used in therapy of menopausal symptoms 0 *ESTROGENS (72-73) *D004966 Estrogens, Conjugated *D010076 Oxazepam D004338 Drug Combinations Z Allgemeinmed 46(1):48;1970 NLM PML TPW M0043510 Ovaribran C0601596 78408-03-4 T073513 Ovaribran C000279 diazan 1970 01 01 2000 12 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 16 *AZO COMPOUNDS (70-77) *SUCCINATES (70-82) *D003979 Diazonium Compounds Cancer Treat Rep 60(11):1601;1976 Dokl Akad Nauk SSSR 236(4):1011;1977 Tsitol Genet 8(5):425;1974 Vopr Onkol 22(2):68;1976 Vopr Onkol 23(5):63;1977 NLM CCR CCR M0040356 diazan C0057735 1,2-bis(diazoacetyl)ethane 19690-35-8 T109 Organic Chemical T121 Pharmacologic Substance T070358 diazan T070357 diazane C023093 tagatose 1,6-diphosphate aldolase 1980 01 01 2001 01 29 1999 2000 2001 2001A 2002 11 HEXOSEDIPHOPHATES (80-82) *D000446 Aldehyde-Lyases J Bacteriol 140(3):1102;1979 NLM CCR CCR M0079902 tagatose 1,6-diphosphate aldolase C0075774 EC 4.1.2.- T109905 tagatose 1,6-diphosphate aldolase T109904 tagatose-1,6-bisphosphate aldolase T109903 Tag-diP aldolase C002788 oxalocrotonate 1972 01 01 1982 08 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN given refers to 4-oxalocrotonate 3 *OXALATES (72-82) *D003437 Crotonates Biochem J 124(2):19P;1971 NLM VSR NLM M0043527 oxalocrotonate C0069721 31540-68-8 T073530 oxalocrotonate C002848 urfadyn 1973 01 01 2001 08 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 6 *NITROFURANTOIN (73-75) ALCOHOL, METHYL (73-75) ALCOHOL, METHYL/analogs (75-76) D009582 Nitrofurantoin *Q000031 analogs ; derivatives J Chromatogr 162(1):110;1979 Paediatr Indones 1979;19(5-6):146 Pharm Weekbl 108(8):149;1973 NLM TWD TWD M0043633 urfadyn C0077875 3-(hydroxymethyl)-1-(((5-nitro-2-furanyl)methylene)amino)- 2,4-imidazolidinedione 1088-92-2 M0043633 M0043631 T073636 urfadyn Merck Index, 9th ed, p. 1267, #9537 Negwer #844 T073633 3-hydroxymethylnitrofurantoin T073635 nifurtoinol M0043631 Urfadyn PL C0147891 M0043633 M0043631 T073634 Urfadyn PL C002796 3-fluoro-5-chloro-2,6-dimethyl-4-pyridinol 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 anticoccidial agents; structure 0 *D011725 Pyridines J Med Chem 16(3):297;1973 NLM NLM M0043542 3-fluoro-5-chloro-2,6-dimethyl-4-pyridinol C0601599 40487-95-4 T073545 3-fluoro-5-chloro-2,6-dimethyl-4-pyridinol C002799 3'-O-acetyl-4-thiothymidine 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *THYMIDINE (73-75) D013936 Thymidine *Q000031 analogs ; derivatives Eur J Biochem 32(3):473;1973 NLM NLM M0043545 3'-O-acetyl-4-thiothymidine C0601602 Thymidine, 4-thio-, 3'-acetate 20188-76-5 T073548 3'-O-acetyl-4-thiothymidine C002801 2,4-dithiouridine 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *THIOURIDINE (73-75) D013891 Thiouridine *Q000031 analogs ; derivatives Eur J Biochem 32(3):473;1973 NLM NLM M0043547 2,4-dithiouridine C0601604 13239-96-8 T073550 2,4-dithiouridine C114912 platinum diamino-4-methylpyridine chloride 1998 10 23 2001 08 22 1999 2000 2001 2001A 2002 cis-isomer is the active cpd; structure in first source 1 *D009944 Organoplatinum Compounds Eur J Biochem 1998 Sep 1;256(2):253-60 BMB CCR CCR M0296123 platinum diamino-4-methylpyridine chloride C0758404 0 M0296123 M0296121 M0296123 M0296122 T326128 platinum diamino-4-methylpyridine chloride T326125 (Pt(NH3)2MePy)Cl M0296121 cis-(Pt(NH3)2Me-Py)Cl C0758402 M0296123 M0296121 T326126 cis-(Pt(NH3)2Me-Py)Cl M0296122 trans-(Pt(NH3)2Me-Py)Cl C0758403 M0296123 M0296122 T326127 trans-(Pt(NH3)2Me-Py)Cl C002809 fuscine 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D011108 Polymers *D011758 Pyrroles Blut 26(2):146;1973 NLM NLM M0043557 fuscine C0601606 0 M0043557 M0043556 T073560 fuscine M0043556 dipyrrylmethene polymer C0601605 M0043557 M0043556 T073559 dipyrrylmethene polymer C108657 tetrachloro(metformin)platinum(IV) 1997 11 03 2001 08 22 1998 1999 2000 2001 2001A 2002 structure in first source 1 *D009944 Organoplatinum Compounds D008687 Metformin *Q000031 analogs ; derivatives J Inorg Biochem 1997 Oct;68(1):53-9 THA CCR CCR M0282249 tetrachloro(metformin)platinum(IV) C0666930 0 T312254 tetrachloro(metformin)platinum(IV) T312251 (metformin)tetrachloroplatinum(IV) T312252 4Cl(metformin)Pt T312253 tetrachloro(N,N-dimethylbiguanide)platinum(IV) C002819 granulose 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D011134 Polysaccharides Biochem J 130(1):4P;1972 Biochem J 144:503;1974 NLM NLM M0043572 granulose C0061876 Granulose 54577-56-9 T073575 granulose C103115 JM 223 1997 01 24 2001 08 22 1998 1999 2000 2001 2001A 2002 1 *D009944 Organoplatinum Compounds Br J Cancer 1996 Dec;74(12):1935-43 PML CCR CCR M0269708 JM 223 C0533194 0 M0269708 M0269707 T299713 JM 223 T299710 JM-223 T299711 JM223 M0269707 ammine diacetatodichloro(propylamine)platinum(IV) C0533196 M0269708 M0269707 T299712 ammine diacetatodichloro(propylamine)platinum(IV) C002827 estr-4-ene-3,11,17-trione 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *17-KETOSTEROIDS (73-76) *ESTRANES (73-75) *D004963 Estrenes J Biol Chem 248(6):2134;1973 NLM NLM M0043590 estr-4-ene-3,11,17-trione C0601610 6615-01-6 T073593 estr-4-ene-3,11,17-trione C089656 JM 335 1994 10 28 2001 08 22 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 6 *D009944 Organoplatinum Compounds Int J Cancer 1994 Oct 1;59(1):65-70 BMB CCR CCR M0237034 JM 335 C0289164 0 M0237034 M0237033 T267039 JM 335 T267036 JM-335 T267037 JM335 M0237033 trans-ammine(cyclohexylamine)dichlorodihydroxo-platinum(IV) C0289163 M0237034 M0237033 T267038 trans-ammine(cyclohexylamine)dichlorodihydroxo-platinum(IV) C002834 antheridiol 1973 01 01 1982 12 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 8 *D010840 Phytosterols Biochem Biophys Res Commun 84(2):417;1978 Dev Biol 51(2):202;1976 J Biol Chem 252(24):8812;1977 J Chem Soc 22(0):2811;1972 Nature 261(5561):599;1976 Tissue Cell l979;11(3):585 NLM VSR NLM M0043602 antheridiol C0051943 3,22,23-trihydroxy-7-oxostigmasta-5,24(28)-dien-29-oic acid gamma-lactone 22263-79-2 T073605 antheridiol C022203 N-acylethanolamines 1980 01 01 2000 12 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 includes N-hexadecanoyl-, N-heptadecanoyl-, N-octadecanoyl- cpds 47 *FATTY ACIDS (80-81) *D004983 Ethanolamines Biochem Biophys Res Commun 90(2):628;1979 NLM CCR CCR M0077957 N-acylethanolamines C0067800 0 T119 Lipid M0077957 M0077956 T107960 N-acylethanolamines M0077956 N-acylethanolamine C0950421 T119 Lipid M0077957 M0077956 T107959 N-acylethanolamine C031105 3-O-methyl-alpha-methyldopamine 1981 08 13 2000 12 22 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 metabolite of p-methoxyamphetamine; RN given refers to parent cpd without isomeric designation 6 DEOXYEPINEPHRINE/*analogs (81-92) D004298 Dopamine *Q000031 analogs ; derivatives Drug Metab Dispos 1981;9(3):250 RLS WXM WXM M0097972 3-O-methyl-alpha-methyldopamine C0095853 13026-44-3 T109 Organic Chemical T124 Neuroreactive Substance or Biogenic Amine 13062-61-8 (HCl) 37751-23-8 (HCl(+-)-isomer) 40829-41-2 ((+-)-isomer) M0097972 M0319105 M0097972 M0319103 M0097972 M0319104 T127976 3-O-methyl-alpha-methyldopamine T127974 4-(2-aminopropyl)-2-methoxyphenol T127975 4-hydroxy-3-methoxyamphetamine M0319105 3-O-methyl-alpha-methyldopamine, (+-)-isomer C0955101 40829-41-2 T109 Organic Chemical T124 Neuroreactive Substance or Biogenic Amine M0097972 M0319105 T349105 3-O-methyl-alpha-methyldopamine, (+-)-isomer 1999 08 18 M0319103 3-O-methyl-alpha-methyldopamine hydrochloride C0955099 13062-61-8 T109 Organic Chemical T121 Pharmacologic Substance T124 Neuroreactive Substance or Biogenic Amine M0097972 M0319103 T349103 3-O-methyl-alpha-methyldopamine hydrochloride 1999 08 18 M0319104 3-O-methyl-alpha-methyldopamine hydrochloride, (+-)-isomer C0955100 37751-23-8 T109 Organic Chemical T121 Pharmacologic Substance T124 Neuroreactive Substance or Biogenic Amine M0097972 M0319104 T349104 3-O-methyl-alpha-methyldopamine hydrochloride, (+-)-isomer 1999 08 18 C002844 pristanic acid 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 61 *D005227 Fatty Acids Biochim Biophys Acta 360(2):166;1974 J Chromatogr Sci 15(5):177;1977 J Supramol Struct 1(2):126;1972 NLM NLM M0043621 pristanic acid C0071987 2,6,10, 14-tetramethylpentadecanoic acid 1189-37-3 T073624 pristanic acid C100250 nifenalol 1986 07 25 2000 12 22 1995 1996 1997 1998 1999 2000 2001 2001A 2002 adrenergic beta-blocker with good antiarrhythmic properties; also tends to lower blood pressure ; provide protection against angina; minor descriptor (75-86); on-line ; INDEX MEDICUS search ETHANOLAMINES (75-86); RN given refers to parent cpd without isomeric designation 9 minor descriptor (75-86); file maintained to ETHANOLAMINES *D004983 Ethanolamines G Ital Dermatol Venereol 1983;118(6):341 PEH CCR CCR M0263176 nifenalol C0068737 5054-57-9 T109 Organic Chemical T121 Pharmacologic Substance 5302-35-2 ((R)-isomer) 5302-36-3 ((S)-isomer) 5704-60-9 (mono-HCl(+-)-isomer) 7349-37-3 (mono-HCl(S)-isomer) 7388-03-6 (mono-HCl(R)-isomer) 7413-36-7 ((+-)-isomer) M0263176 M0327475 M0263176 M0327470 M0263176 M0327471 M0263176 M0327472 M0263176 M0327474 M0263176 M0327473 T293181 nifenalol Merck Index,10th ed, #6375. T293179 1-(4-nitrophenyl)-2-isopropylaminoethanol T293180 inpea M0327475 nifenalol, (+-)-isomer C0960028 7413-36-7 T109 Organic Chemical T121 Pharmacologic Substance M0263176 M0327475 T357475 nifenalol, (+-)-isomer 1999 08 18 M0327470 nifenalol, (R)-isomer C0960024 5302-35-2 T109 Organic Chemical T121 Pharmacologic Substance M0263176 M0327470 T357470 nifenalol, (R)-isomer 1999 08 18 M0327471 nifenalol, (S)-isomer C0960025 5302-36-3 T109 Organic Chemical T121 Pharmacologic Substance M0263176 M0327471 T357471 nifenalol, (S)-isomer 1999 08 18 M0327472 nifenalol monohydrochloride, (+-)-isomer C0960026 5704-60-9 T109 Organic Chemical T121 Pharmacologic Substance M0263176 M0327472 T357472 nifenalol monohydrochloride, (+-)-isomer 1999 08 18 M0327474 nifenalol monohydrochloride, (R)-isomer C0960027 7388-03-6 T109 Organic Chemical T121 Pharmacologic Substance M0263176 M0327474 T357474 nifenalol monohydrochloride, (R)-isomer 1999 08 18 M0327473 nifenalol monohydrochloride, (S)-isomer C0970917 7349-37-3 T109 Organic Chemical T121 Pharmacologic Substance M0263176 M0327473 T357473 nifenalol monohydrochloride, (S)-isomer 1999 08 18 C088780 O-methyl-methionine-dichloroplatinum(II) 1994 09 08 2001 08 22 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN refers to stereoisomer; structure given in first source 1 *D009944 Organoplatinum Compounds J Inorg Biochem 1994 Aug 15;55(3):175-81 PML CCR CCR M0234900 O-methyl-methionine-dichloroplatinum(II) C0257954 139014-07-6 139066-04-9 (stereoisomer) M0234900 M0326642 T264905 O-methyl-methionine-dichloroplatinum(II) T264903 Pt(O-Me-Met)Cl2 T264904 Pt(O-methyl-methionine)Cl2 M0326642 O-methyl-methionine-dichloroplatinum(II), stereoisomer C0970855 139066-04-9 M0234900 M0326642 T356642 O-methyl-methionine-dichloroplatinum(II), stereoisomer 1999 08 18 C002850 4,7-diphenylphenanthroline sulfonate 1973 01 01 1998 01 09 1998 1999 2000 2001 2002 color reagent for serum iron 6 ARYL SULFONATES (74-76) LIGANDS (73-82) *D010618 Phenanthrolines Ann Clin Lab Sci 1(1):14;1972 NLM BQV NLM M0043638 4,7-diphenylphenanthroline sulfonate C0047879 4,7-diphenyl-1,10-phenanthrolinesulfonic acid 40795-59-3 M0043638 M0043637 T073641 4,7-diphenylphenanthroline sulfonate M0043637 bathophenanthroline sulfonate C0105268 M0043638 M0043637 T073640 bathophenanthroline sulfonate C002903 formohydroxamic acid 1973 01 01 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 2 *D006877 Hydroxamic Acids Experientia 29(2):228;1973 NLM TWD TWD M0043722 formohydroxamic acid C0060655 4312-87-2 T073725 formohydroxamic acid T073724 formhydroxamic acid C111884 der p 10 protein 1998 05 14 2001 01 30 1998 1999 2000 2000A 2001 2001A 2002 an allergen from the dust mite Dermatophagoides pteronyssinus; amino acid sequence in first source; GenBank Y14906 2 *D000485 Allergens *D014335 Tropomyosin D008925 Mites Biochim Biophys Acta 1998 Apr 1;1397(1):27-30 SZM CCR CCR M0289555 der p 10 protein C0674102 0 T319560 der p 10 protein T319558 der p 10 gene product T319559 der-p-10 gene product C115315 Asp f 3 allergen 1998 11 13 2001 01 30 1999 2000 2001 2001A 2002 18.5-kDa peroxisomal protein isolated from Aspergillus fumigatus 2 *D000485 Allergens D005656 Fungal Proteins Int Immunol 1998 Aug;10(8):1211-6 THA CCR CCR M0296996 Asp f 3 allergen C0759259 0 T327001 Asp f 3 allergen T326999 allergen Asp f 3 T327000 rASP f 3 allergen C002862 homothiotaurine 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *TAURINE (73-75) SULFHYDRYL COMPOUNDS (73-75) D013654 Taurine *Q000031 analogs ; derivatives Analyt Biochem 51(1);1973 NLM NLM M0043656 homothiotaurine C0601618 3-aminopropanethiosulfonic acid 40957-87-7 T073659 homothiotaurine C002863 homohypotaurine 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *TAURINE (73-75) SULFINIC ACIDS (73-76) D013654 Taurine *Q000031 analogs ; derivatives Anal Biochem 51(1):265;1973 Physiol Chem Phys 10(5):435;1978 NLM NLM M0043657 homohypotaurine C0062942 3-aminopropansulfinic acid 25346-09-2 T073660 homohypotaurine C002886 Bax 439 1973 01 01 2001 08 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 decreases concentrating ability of kidney; RN given refers to parent cpd 15 *D013844 Thiazoles Lab Invest 31(6):658;1974 Proc Soc Exp Biol Med 142(2):720;1973 NLM TWD TWD M0043689 Bax 439 C0053014 4,5-diphenyl-2-thiazolamine, monohydrochloride 6318-74-7 36761-88-3 (HCl) M0043689 M0043687 M0043689 M0308103 T073692 Bax 439 T073691 Bax-439 M0043687 2-amino-4,5-diphenylthiazole C0092474 M0043689 M0043687 T073690 2-amino-4,5-diphenylthiazole M0308103 Bax 439 hydrochloride C0951148 36761-88-3 M0043689 M0308103 T338103 Bax 439 hydrochloride 1999 08 18 C002867 beta-hydroxyethyl-2,4-dinitrophenyl disulfide 1973 01 01 1982 08 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 used for characterizing protein thiol groups 0 *NITROBENZENES (73-77) DISULFIDES (73-76) *D004136 Dinitrobenzenes D013439 Sulfhydryl Reagents Acta Pol Pharm 29(4):439;1972 Ann Univ Mariae Curie Sklodowska Med 30(17):131;1976 Pol J Pharmacol Pharm 27:493;1975 NLM CHA NLM M0043665 beta-hydroxyethyl-2,4-dinitrophenyl disulfide C0053452 HEDD /OD/ 2-((2,4-dinitrophenyl)dithio)ethanol 955-59-9 T073668 beta-hydroxyethyl-2,4-dinitrophenyl disulfide C002869 8-azainosine 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *INOSINE (73-75) AZA COMPOUNDS (73-76) D007288 Inosine *Q000031 analogs ; derivatives Cancer Res 33(3):465;1973 J Med Chem 20(1):116;1977 NLM NLM M0043666 8-azainosine C0050031 4968-68-7 T073669 8-azainosine C115316 Asp f 4 allergen 1998 11 13 2001 01 30 1999 2000 2001 2001A 2002 30-kDa protein isolated from Aspergillus fumigatus 2 *D000485 Allergens D005656 Fungal Proteins Int Immunol 1998 Aug;10(8):1211-6 THA CCR CCR M0296999 Asp f 4 allergen C0759262 0 T327004 Asp f 4 allergen T327002 allergen Asp f 4 T327003 rAsp f 4 allergen C115317 Asp f 6 allergen 1998 11 13 2001 01 30 1999 2000 2001 2001A 2002 23-kDa manganase superoxide dismutase isolated from Aspergillus fumigatus 4 *D000485 Allergens *D013482 Superoxide Dismutase D005656 Fungal Proteins Int Immunol 1998 Aug;10(8):1211-6 THA CCR CCR M0297002 Asp f 6 allergen C0759265 0 T327007 Asp f 6 allergen T327005 allergen Asp f 6 T327006 rAsp f 6 allergen C002881 1-hydroxy-2-ketoheptadecane 1973 01 01 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 KETONES (73-74) *D005233 Fatty Alcohols Biochim Biophys Acta 296(2):265;1973 NLM NLM M0043677 1-hydroxy-2-ketoheptadecane C0601628 1-hydroxy-2-heptadecanone 41265-63-8 T073680 1-hydroxy-2-ketoheptadecane C006212 BS 7564 1974 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *TROPANES (74-82) *D003986 Dibenzocycloheptenes Arch Int Pharmacodyn Ther 205(1):61;1973 NLM TWD TWD M0048507 BS 7564 C0602548 8-azoniabicyclo(3.2.1)octane, 3-(((10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)carbonyl)oxy)-8,8-dimethyl-, bromide, endo- 7530-51-0 M0048507 M0048506 T078510 BS 7564 M0048506 10,11-dihydro-5H-dibenzo(a,d)cycloheptene-5-carboxylic acid tropine ester methobromide C0602547 M0048507 M0048506 T078509 10,11-dihydro-5H-dibenzo(a,d)cycloheptene-5-carboxylic acid tropine ester methobromide C002884 ophiobolins 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 tricyclic sesterterpenes, include ophiobolins A,B,C,D,F; RN in Chemline for ophiobolin A: 4611-05-6; RN for ophiobolin B: 5601-74-1; RN for ophiobolin C: 19022-51-6; structure 4 *D013729 Terpenes Biochim Biophys Acta 296(3):615;1973 NLM NLM M0043685 ophiobolins C0282748 0 T073688 ophiobolins Merck Index, 9th ed, p. 248, #1935 - ophiobolin D C006223 Abbott 40060 1975 01 01 2001 01 30 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 ISOQUINOLINES (75-81) *D014230 Triazoles Arch Int Pharmacodyn 212(2):205;1974 NLM TWD TWD M0048537 Abbott 40060 C0602564 3-trifluoromethyl-s-triazolo(3,4-a)-isoquinoline 27022-50-0 M0048537 M0048536 T078540 Abbott 40060 M0048536 NC 1140 C0602563 M0048537 M0048536 T078539 NC 1140 C432948 11-tetradecenoic acid 2001 08 17 2001 2002 metabolite formed during the biosynthesis of the Spodoptera littoralis sex pheromone; structure in first source 2 *D005229 Fatty Acids, Monounsaturated Insect Biochem Mol Biol 2001 Jun 22;31(8):799-803 THA THA M0395876 11-tetradecenoic acid C0968738 0 T119 Lipid T457920 11-tetradecenoic acid 2001 08 17 C432949 9,11-tetradecadienoic acid 2001 08 17 2001 2002 formed during the biosynthesis of the Spodoptera littoralis sex pheromone; structure in first source 1 *D005231 Fatty Acids, Unsaturated Insect Biochem Mol Biol 2001 Jun 22;31(8):799-803 THA THA M0395877 9,11-tetradecadienoic acid C0968739 0 T119 Lipid T457921 9,11-tetradecadienoic acid 2001 08 17 C002891 3-methoxyxanthine 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 METHYL ETHERS (73-76) *D014970 Xanthines Biochemistry 11(25):4844;1972 NLM NLM M0043702 3-methoxyxanthine C0601630 1H-Purine-2,6-dione, 3,7-dihydro-3-methoxy- 30345-91-6 T073705 3-methoxyxanthine C432950 HLSG-1 protein 2001 08 17 2001 2002 isolated from the hard tick Haemoaphysalis longicornis; amino acid sequence in first source 1 *D012697 Serine Endopeptidases Insect Biochem Mol Biol 2001 Jun 22;31(8):817-25 THA THA M0395878 HLSG-1 protein C0968740 EC 3.4.21.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T457922 HLSG-1 protein 2001 08 17 C002898 ceramide aminoethylphosphonate 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 ETHYLAMINES (73-75) ORGANOPHOSPHORUS CPDS (73-75) *D002518 Ceramides D000615 Aminoethylphosphonic Acid *Q000031 analogs ; derivatives Biochim Biophys Acta 296(1):171;1973 Biochim Biophys Acta 486(1):172;1977 NLM RLS NLM M0043713 ceramide aminoethylphosphonate C0055087 0 T073716 ceramide aminoethylphosphonate C002900 3 beta-(beta-dimethylaminoethoxy)androst-5-en-17-one 1973 01 01 1981 12 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 17-KETOSTEROIDS (73-81) ETHYL ETHERS (73-76) *D000736 Androstenes Arch Biochem Biophys 180:465;1977 Biochem Pharm 25(11):1249;1976 Biochim Biophys Acta 296(1):221;1973 Lipids 1979;14(8):741 NLM NBM NLM M0043717 3 beta-(beta-dimethylaminoethoxy)androst-5-en-17-one C0046742 7635-03-2 T073720 3 beta-(beta-dimethylaminoethoxy)androst-5-en-17-one C002908 2-thiocytidine 1973 01 01 1983 07 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 7 *CYTIDINE (73-75) THIONES (74-76) D003562 Cytidine *Q000031 analogs ; derivatives Biochemistry 18(1):91;1979 Eur J Biochem 33(3):545;1973 NLM ACS NLM M0043727 2-thiocytidine C0046571 13239-97-9 T073730 2-thiocytidine C002911 8-azaethynylestradiol 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ETHINYL ESTRADIOL (73-75) AZA COMPOUNDS (73-76) D004997 Ethinyl Estradiol *Q000031 analogs ; derivatives Steroid Lip Res 3(2):185;1972 NLM NLM M0043735 8-azaethynylestradiol C0601641 39650-18-5 T073738 8-azaethynylestradiol C002914 7-oxodehydroepiandrosterone 1973 01 01 1992 06 18 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 *DEHYDROEPIANDROSTERONE (73-75) KETOSTEROIDS (73-76) D003687 Prasterone *Q000031 analogs ; derivatives Steroid Lipid Res 3(2):170;1972 NLM MLH TPW M0043740 7-oxodehydroepiandrosterone C0525091 3 beta-hydroxyandrost-5-ene-7,17-dione 566-19-8 T073743 7-oxodehydroepiandrosterone C002918 methylthioinosine dicarboxaldehyde 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *INOSINE (73-75) ALDEHYDES (73-76) SULFIDES (73-75) D008778 Methylthioinosine *Q000031 analogs ; derivatives Cancer Res 33(4):856;1973 NLM NLM M0043747 methylthioinosine dicarboxaldehyde C0066439 31654-43-0 T073750 methylthioinosine dicarboxaldehyde C002920 retamycin 1973 01 01 1995 07 28 1996 1997 1998 1999 2000 2001 2002 0 POLYCYCLIC COMPOUNDS (73-95) D018943 Anthracyclines Rev Inst Antibiot (Recife) 11(1):3;1971 NLM BVL BVL M0043748 retamycin C0601645 11130-68-0 T073751 retamycin C002924 N-bromoacetyl-beta-D-galactosylamine 1973 01 01 1984 01 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *GALACTOSAMINE (73-76) ACETIC ACIDS (73-76) D000116 Acetylgalactosamine *Q000031 analogs ; derivatives Biochim Biophys Acta 410(2):347;1975 Nature (New Biol) 242(115):52;1973 NLM DLJ NLM M0043759 N-bromoacetyl-beta-D-galactosylamine C0067857 Acetamide, 2-bromo-N-beta-D-galactopyranosyl- 29086-04-2 T073762 N-bromoacetyl-beta-D-galactosylamine C002928 Deluteval 1973 01 01 1990 07 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 Contains estradiol valerate and hydroxyprogesterone caproate 0 *ESTRADIOL (73-75) *HYDROXYPROGESTERONE (73-75) *D006908 Hydroxyprogesterones D004338 Drug Combinations D004958 Estradiol *Q000031 analogs ; derivatives J Reprod Med 10(3):98;1973 NLM SXR NLM M0043763 Deluteval C0601652 Pregn-4-ene-3,20-dione, 17-((1-oxohexyl)oxy)-, mixt. with (17beta)-3-hydroxyestra-1,3,5(10)-trien-17-yl pentanoate 70643-78-6 T073766 Deluteval C002930 L-fuconate dehydratase 1975 01 01 1982 02 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 FUCOSE/analogs (75-82) SUGAR ACIDS (75-82) *D006836 Hydro-Lyases J Biol Chem 254(15):7060;1979 Methods Enzymol 42(C):305;1975 NLM NBM NLM M0043764 L-fuconate dehydratase C0064536 EC 4.2.1.68 T073767 L-fuconate dehydratase C002990 butyl isocyanide 1973 01 01 2001 01 11 1996 1997 1998 1999 2000 2001 2001A 2002 14 BUTANES (73-76) *D009570 Nitriles J Biol Chem 248(5):1616;1973 J Biol Chem 252(12):4102;1977 NLM CCR CCR M0043882 butyl isocyanide C0054278 2769-64-4 T109 Organic Chemical T073885 butyl isocyanide T073883 1-isocyanobutane T073884 n-butylisocyanide C002938 polyfructosan 1973 01 01 1984 05 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 29 *POLYSACCHARIDES (73-75) FRUCTOSE (73-75) *D005630 Fructans Eur J Pharmacol 30(2):182;1975 Lab Pract 22(4):256;1973 Pfluegers Arch 369:281;1977 NLM DLJ NLM M0043780 polyfructosan C0071572 39421-73-3 M0043780 M0043777 M0043780 M0043778 M0043780 M0043779 T073783 polyfructosan M0043777 Fructan S C0118252 M0043780 M0043777 T073780 Fructan S M0043778 polyfructan-A48 C0137778 M0043780 M0043778 T073781 polyfructan-A48 M0043779 polyfructosan-S C0137779 M0043780 M0043779 T073782 polyfructosan-S C002941 20-hydroperoxy-5-pregnen-3-beta-ol 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 HYDROXYSTEROIDS (73-76) PEROXIDES (73-76) *D011283 Pregnenes Steroids 21(4):521;1973 NLM NLM M0043785 20-hydroperoxy-5-pregnen-3-beta-ol C0601655 0 T073788 20-hydroperoxy-5-pregnen-3-beta-ol C002949 16 beta-21-methyl-D-nor-5-pregnen-3 beta-ol-20,21-dione 21-ethylene ketal 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PREGNENES (73-76) HYDROXYSTEROIDS (74-76) PREGNENEDIONES (73-82) *D009652 Norpregnenes Steroids Lipids Res 3(4):201;1972 NLM VSR NLM M0043797 16 beta-21-methyl-D-nor-5-pregnen-3 beta-ol-20,21-dione 21-ethylene ketal C0601658 Methanone, ((3beta,16beta)-3-hydroxy-D-norandrost-5-en-16-yl)(2-methyl-1,3-dioxolan-2-yl)- 39932-40-6 T073800 16 beta-21-methyl-D-nor-5-pregnen-3 beta-ol-20,21-dione 21-ethylene ketal C023694 ferredoxin-nitrite reductase 1980 04 25 2001 01 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 14 *D009572 Nitrite Reductases FEBS Lett 1980;111(2):377 RLS CCR CCR M0081222 ferredoxin-nitrite reductase C0060224 EC 1.7.7.1 T116 Amino Acid, Peptide, or Protein T126 Enzyme T111225 ferredoxin-nitrite reductase C002960 isotachysterol 1973 01 01 1998 04 17 1998 1999 2000 2001 2002 RN given refers to (3beta,6E,22E)-isomer 3 *SECOSTEROIDS (73-82) *STEROLS (73-79) D004875 Ergosterol *Q000031 analogs ; derivatives Anal Biochem 52(2):584;1973 J Assoc Off Anal Chem 60(5):989;1977 NLM BQV NLM M0043813 isotachysterol C0064081 6E-9,10-secoergosta-5(10),6,8(14),22E-tetraen- 3 beta-ol 469-06-7 T073816 isotachysterol C409628 17-dimethylaminolobohedleolide 2000 06 20 2000 2001 2002 isolated from the soft coral Lobophytum; structure in first source 1 *D001643 Bicyclo Compounds *D005663 Furans J Nat Prod 2000 Apr;63(4):531-3 THA THA M0364577 17-dimethylaminolobohedleolide C0914994 0 T109 Organic Chemical T121 Pharmacologic Substance T417256 17-dimethylaminolobohedleolide 2000 06 20 C003117 phosalone 1972 01 01 2002 01 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 2002A structure 49 *D009946 Organothiophosphorus Compounds Bull Environ Contam Toxicol 12(6):682;1974 Bull Environ Contam Toxicol 18(2):219;1977 Bull Environ Contam Toxicol 20(2):255;1978 Egypt J Bilharz 2(2):223;1975 Enzyme 1979;24(5):281 Gig Sanit 12:87;1977 Gig Sanit 1979;(12):11 Gig Truda Prof Zabol 1979;(12):45 J Agric Food Chem 20(1):161;1972 J Agric Food Chem 25(1):215;1977 J Agric Food Chem 25(2):342;1977 Probl Khig 2:209;1976 Sci Total Environ 1979;13(3):235 Toxicol Appl Pharmacol 36(3):561;1976 Toxicol Appl Pharmacol 37(1):85;1976 Toxicol Appl Pharmacol 46(2):363;1978 Toxicol Appl Pharmacol 47(2):353;1979 Veterinariia 4:93;1975 NLM CCR CCR M0044070 phosalone C0070762 S-((6-chloro- 2-oxo-3H)-benzoxazolylmethyl)O,O-diethyl phosphorodithioate 2310-17-0 T115 Organophosphorus Compound T131 Hazardous or Poisonous Substance D002800 Cholinesterase Inhibitors D007311 Insecticides, Organothiophosphate M0044070 M0044065 T074073 phosalone T074069 fosalon T074070 fozalone T074071 phoazlone T074072 phozalone M0044065 Zolone C0950184 T115 Organophosphorus Compound T131 Hazardous or Poisonous Substance M0044070 M0044065 T074068 Zolone C002971 clobenfurol 1973 01 01 1982 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 BENZYL ALCOHOLS (73-82) *D001572 Benzofurans Clin Terap 82:351;1977 Minerva Cardioangiol 21(1):60;1973 Minerva Cardioangiol 22(4):323;1974 Minerva Cardioangiol 24(1):25;1976 Minerva Cardioangiol 24(7-8):527;1976 Minerva Med 67(21):1394;1976 NLM NBM NLM M0043841 clobenfurol C0055892 3611-72-1 M0043841 M0043836 M0043841 M0043838 M0043841 M0043840 M0043841 M0043837 M0043841 M0043839 T073844 clobenfurol Merck Index, 9th ed, #2328 M0043836 2-benzofuryl-p-chlorophenylcarbinol C0092644 M0043841 M0043836 T073839 2-benzofuryl-p-chlorophenylcarbinol M0043838 cloridarol C0110098 M0043841 M0043838 T073841 cloridarol M0043840 menacor C0127513 M0043841 M0043840 T073843 menacor M0043837 chloridarol C0109378 M0043841 M0043837 T073840 chloridarol M0043839 cloridol C0110099 M0043841 M0043839 T073842 cloridol C443124 Dsg protein, Streptococcus 2002 01 08 2002 similar to TrsA from Yersinia enterocolitica; isolated from Streptococcus gordonii; GenBank U12643; do not confuse with Dsg protein 1 *D008565 Membrane Proteins Microbiology 2001 Nov;147(Pt 11):3061-70 THA THA M0409881 Dsg protein, Streptococcus 0 T116 Amino Acid, Peptide, or Protein T476522 Dsg protein, Streptococcus 2002 01 08 T476523 dsg gene product, Streptococcus 2002 01 08 C008704 pyrithione 1975 01 01 2001 01 11 1998 1999 2000 2001 2001A 2002 split from cephalosporin molecule; RN given refers to parent cpd; structure 64 CYCLIC N-OXIDES (75-82) *D011725 Pyridines D005710 Gallium Radioisotopes D007205 Indium Radioisotopes Acta Derm Venerol (Stockh) 1979;59(6):521 Antimicrob Ag Chemother 10(2):249;1976 Antimicrob Ag Chemother 14(1):60;1978 Arch Environ Contam Toxicol 1979;8(3):355- Clin Toxicol 13(1):1;1978 Food Cosmet Toxicol 15(1):43;1977 Prensa Med Mex 42(7-8):319;1977 Toxicol Appl Pharmacol 43:373;1978 Toxicology 5(2):209;1975 NLM TWD TWD M0052791 pyrithione C0072735 1-hydroxy- 2(1H)-pyridinethione 1121-30-8 T109 Organic Chemical T121 Pharmacologic Substance D000935 Antifungal Agents D019275 Radiopharmaceuticals 15922-78-8 (Na salt) 25142-21-6 (Ba[2:1] salt) 30569-24-5 (Ca[2:1] salt) 33397-03-4 (K salt) 64420-92-4 (Mg[2:1] salt) M0052791 M0052785 M0052791 M0052786 M0052791 M0310427 M0052791 M0310428 M0052791 M0052788 M0052791 M0310429 M0052791 M0310430 M0052791 M0310426 M0052791 M0052789 M0052791 M0052790 T082794 pyrithione Merck Index, 9th ed, p. 1037, #7775 Negwer #213 T082786 2-mercaptopyridine N-oxide T082785 2-HPT cpd T082787 2-pyridinethiol 1-oxide T082790 N-hydroxypyridine-2-thione M0052785 67Ga-MPO C0603680 T130 Indicator, Reagent, or Diagnostic Aid T196 Element, Ion, or Isotope M0052791 M0052785 T082788 67Ga-MPO M0052786 68Ga-mercaptopyridine-N-oxide C0603681 T130 Indicator, Reagent, or Diagnostic Aid T196 Element, Ion, or Isotope M0052791 M0052786 T082789 68Ga-mercaptopyridine-N-oxide M0310427 pyrithione barium (2:1) salt C0951917 25142-21-6 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0052791 M0310427 T340427 pyrithione barium (2:1) salt 1999 08 18 M0310428 pyrithione calcium (2:1) salt C0951918 30569-24-5 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0052791 M0310428 T340428 pyrithione calcium (2:1) salt 1999 08 18 M0052788 indium 111-2-mercaptopyridine-1-oxide C0123477 T130 Indicator, Reagent, or Diagnostic Aid T196 Element, Ion, or Isotope M0052791 M0052788 T082791 indium 111-2-mercaptopyridine-1-oxide M0310429 pyrithione potassium salt C0951919 33397-03-4 T109 Organic Chemical T121 Pharmacologic Substance M0052791 M0310429 T340429 pyrithione potassium salt 1999 08 18 M0310430 pyrithione magnesium salt C0951920 64420-92-4 T109 Organic Chemical T121 Pharmacologic Substance M0052791 M0310430 T340430 pyrithione magnesium salt 1999 08 18 M0310426 pyrithione sodium salt C0951916 15922-78-8 T109 Organic Chemical T121 Pharmacologic Substance M0052791 M0310426 T340426 pyrithione sodium salt 1999 08 18 M0052789 Omadine C0133840 T109 Organic Chemical T121 Pharmacologic Substance M0052791 M0052789 T082792 Omadine M0052790 sodium pyridinethione C0142917 T109 Organic Chemical T121 Pharmacologic Substance M0052791 M0052790 T082793 sodium pyridinethione C409627 lobohedleolide 2000 06 20 2000 06 20 2000 2000A 2001 2002 RN given for (3aS-(3aR*,6E,10E,14E,15aR*))-isomer; isolated from the soft coral Lobophytum; structure in first source 2 *D001643 Bicyclo Compounds *D005663 Furans J Nat Prod 2000 Apr;63(4):531-3 THA THA THA M0364576 lobohedleolide C0914993 81026-38-2 T109 Organic Chemical T121 Pharmacologic Substance T417255 lobohedleolide 2000 06 20 C061872 FK 409 1989 12 30 2001 01 11 1999 2000 2001 2001A 2002 structure given in first source; from Streptomyces griseoporeus 80 *D009574 Nitro Compounds D000254 Na(+)-K(+)-Exchanging ATPase Q000037 antagonists ; inhibitors J Antibiot (Tokyo) 1989;42(11):1584 TPW CCR CCR M0171464 FK 409 C0060403 3-Hexenamide, 4-ethyl-2-(hydroxyimino)-5-nitro-, (E)- 92454-60-9 T109 Organic Chemical T121 Pharmacologic Substance D000959 Antihypertensive Agents D004791 Enzyme Inhibitors D010975 Platelet Aggregation Inhibitors D014665 Vasodilator Agents D020030 Nitric Oxide Donors M0171464 M0171462 T201469 FK 409 T201468 FK-409 M0171462 4-ethyl-2-hydroxyimino-5-nitro-3-hexenecarboxamide C0096967 T109 Organic Chemical T121 Pharmacologic Substance M0171464 M0171462 T201467 4-ethyl-2-hydroxyimino-5-nitro-3-hexenecarboxamide C409629 tylopiol A 2000 06 20 2000 2001 2002 isolated from the fungus Tylopilus plumbeoviolaceus; structure in first source 1 *D012632 Secosteroids D004875 Ergosterol *Q000031 analogs ; derivatives J Nat Prod 2000 Apr;63(4):534-6 THA THA M0364578 tylopiol A C0914995 0 T110 Steroid T417257 tylopiol A 2000 06 20 T417258 3-hydroxy-8,9-oxido-8,9-secoergosta-7,9(11),22-triene 2000 06 20 C011801 2,2'-dithiobis(5-nitropyridine) 1976 01 01 2001 01 11 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2001B 2002 structure 12 DISULFIDES (76-82) *D011725 Pyridines D013439 Sulfhydryl Reagents Biochim Biophys Acta 423(3):590;1976 Biochim Biophys Acta 459(1):20;1977 NLM TWD TWD M0058381 2,2'-dithiobis(5-nitropyridine) C0045259 2127-10-8 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T088384 2,2'-dithiobis(5-nitropyridine) T088382 2,2-DNP T088381 2,2'-dithio-bis(5-nitropyridine) T088383 DTBNP C002987 4,5-dihydro-1,3-dimethyl-1,H-pyrazolo-(3,4-b)(1,4)- benzoxazepine 1973 01 01 1989 08 08 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN given refers to HCl; RN for parent cpd not in Chemline 8/4/83; structure 0 *BENZAZEPINES (73-75) PYRAZOLES (73-82) *D010077 Oxazepines Arch Int Pharmacodyn 202(1):119;1973 NLM RJM RLS M0043871 4,5-dihydro-1,3-dimethyl-1,H-pyrazolo-(3,4-b)(1,4)- benzoxazepine C0601664 34375-78-5 M0043871 M0043870 T073874 4,5-dihydro-1,3-dimethyl-1,H-pyrazolo-(3,4-b)(1,4)- benzoxazepine M0043870 4,5-dihydro-1,3-dimethyl-1,H-pyrazolo-(3,4-b)(1,4)-benzoxazepine, monohydrochloride C0601663 M0043871 M0043870 T073873 4,5-dihydro-1,3-dimethyl-1,H-pyrazolo-(3,4-b)(1,4)-benzoxazepine, monohydrochloride C409630 tylopiol B 2000 06 20 2000 2001 2002 isolated from the fungus Tylopilus plumbeoviolaceus; structure in first source 1 *D012632 Secosteroids D004875 Ergosterol *Q000031 analogs ; derivatives J Nat Prod 2000 Apr;63(4):534-6 THA THA M0364579 tylopiol B C0914996 0 T110 Steroid T417259 tylopiol B 2000 06 20 T417260 3-hydroxy-8,9-oxido-8,9-secoergosta-7,22-dien-12-one 2000 06 20 C013109 metapyrone 1976 01 01 2001 01 11 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 inhibits adrenal 11 beta-hydroxylase 98 *D011725 Pyridines Mater Med Pol 8(2):108;1976 NLM TWD TWD M0060621 metapyrone C0066058 17286-92-9 T109 Organic Chemical T121 Pharmacologic Substance T090624 metapyrone T090623 2-methyl-1,2(bispyridyl)-1-propanone C002991 beta-methyl-asparagine 1973 01 01 1998 03 31 1998 1999 2000 2001 2002 RN given refers to (DL-threo)-isomer; structure 0 *ASPARAGINE (73-75) D001216 Asparagine *Q000031 analogs ; derivatives J Biol Chem 248(5):1741;1973 NLM BQV NLM M0043883 beta-methyl-asparagine C0601665 50817-24-8 T073886 beta-methyl-asparagine C443125 MrpA protein, Microcystis aeruginosa 2002 01 08 2002 a microcystin-related protein; GenBank AJ271976 1 *D020418 Algal Proteins Microbiology 2001 Nov;147(Pt 11):3113-9 THA THA M0409882 MrpA protein, Microcystis aeruginosa 0 T116 Amino Acid, Peptide, or Protein T476524 MrpA protein, Microcystis aeruginosa 2002 01 08 T476525 mrpA gene product, Microcystis aeruginosa 2002 01 08 C443126 Pint1 protein 2002 01 08 2002 binds cellular PrP; GenBank AY029599 1 *D002352 Carrier Proteins Microbiology 2001 Nov;147(Pt 11):44604-12 THA THA M0409883 Pint1 protein 0 T116 Amino Acid, Peptide, or Protein T476526 Pint1 protein 2002 01 08 T476527 prion interactor 1 2002 01 08 C003000 histocon 1973 01 01 1982 08 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 tissue transport medium used in lipid histochemical analysis of biopsies 0 *D012996 Solutions D014021 Tissue Preservation Histochemie 34(3):249;1973 NLM VSR NLM M0043904 histocon C0601669 39346-80-0 T073907 histocon C443127 PPO 464 2002 01 08 2002 structure in first source 1 *D001381 Azepines *D011725 Pyridines Microbiology 2001 Nov;147(Pt 11):44653-62 THA THA M0409884 PPO 464 0 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance T476528 PPO 464 2002 01 08 T476529 PPO-464 2002 01 08 T476530 PPO464 2002 01 08 C003018 5-oxo-2,5-seco-A-dinorcholestan-2-amide 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *NORSTEROIDS (72-75) *SECOSTEROIDS (72-75) *D002776 Cholestanes J Chem Soc (Perkin I)21:2755;1972 NLM NLM M0043927 5-oxo-2,5-seco-A-dinorcholestan-2-amide C0601677 0 T073930 5-oxo-2,5-seco-A-dinorcholestan-2-amide C003037 palmitoyl dihydroxyacetone phosphate 1972 01 01 2001 02 27 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 10 *PALMITIC ACIDS (75-82) *TRIOSES (72-75) ORGANOPHOSPHORUS CPDS (73-75) D004099 Dihydroxyacetone Phosphate *Q000031 analogs ; derivatives J Biol Chem 247(9):2944;1972 NLM CCR CCR M0043968 palmitoyl dihydroxyacetone phosphate C0069970 hexadecanoic acid 2-oxo-3-(phosphonooxy)propyl ester 17378-38-0 T073971 palmitoyl dihydroxyacetone phosphate T073969 hexadecanoyl dihydroxyacetone phosphate T073970 palmitoyl glycerone phosphate C416933 ABT 702 2000 12 16 2001 2002 structure in first source 6 *D009025 Morpholines *D011743 Pyrimidines D000248 Adenosine Kinase Q000037 antagonists ; inhibitors J Pharmacol Exp Ther 2000 Dec;295(3):1156-64 THA THA M0374723 ABT 702 C0962529 0 T109 Organic Chemical T121 Pharmacologic Substance T431151 ABT 702 2000 12 16 T431152 ABT-702 2000 12 16 T431153 4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido(2,3-d)pyrimidine 2000 12 16 C029597 Concise-Cap-C-Rynge 1981 06 08 2001 03 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 photoactivated composite dental restorative material 1 *D003188 Composite Resins J Dent 1981;9(1):36 NBM TWD TWD M0094322 Concise-Cap-C-Rynge C0612969 Concise-Cap-C-Rynge 78590-47-3 T124325 Concise-Cap-C-Rynge T124324 CCCR C087654 3'-O-galactopyranosyl-1-4-O-galactopyranosylcytarabine 1994 07 08 2001 03 01 1996 1997 1998 1999 2000 2001 2001A 2002 structure in first source 1 *D004187 Disaccharides D003561 Cytarabine *Q000031 analogs ; derivatives Biosci Biotechnol Biochem 1994 Apr;58(4):639-43 THA CCR CCR M0232113 3'-O-galactopyranosyl-1-4-O-galactopyranosylcytarabine C0255607 155603-73-9 T262118 3'-O-galactopyranosyl-1-4-O-galactopyranosylcytarabine T262116 3'-Gal-1-4-Gal-ara-C T262117 3'-O-galactopyranosyl-1-4-O-galactopyranosyl-ara-C C003033 pachymaran 1972 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 derived from a natural glucan, pachyman 0 *POLYSACCHARIDES (72-79) *D005936 Glucans Cell Immunol 38(2):328;1978 Chem Biol Interact 3(1):69;1971 NLM NLM M0043963 pachymaran C0069929 65637-98-1 T073966 pachymaran C029606 hemoglobin Genova 1981 06 01 2001 03 01 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 Leu replaced by Pro at position 28 on beta chain 3 *D006455 Hemoglobins, Abnormal Biochim Biophys Acta 1981;667(2):233 RLS TWD TWD M0094345 hemoglobin Genova C0062319 9034-78-0 T124348 hemoglobin Genova T124347 Hb Genova C061823 2-propylpentanal diisopropyl acetal 1989 12 27 2000 08 03 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2000B 2001 2002 structure given in first source; precursor to valproic acid 1 *D000080 Acetals Drug Metab Dispos 1989;17(5):233 WMM TWD TWD M0171319 2-propylpentanal diisopropyl acetal C0638841 124345-19-3 T109 Organic Chemical T121 Pharmacologic Substance T201324 2-propylpentanal diisopropyl acetal T201323 PPDIIA C087758 difructose anhydride III 1994 07 14 2001 03 01 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a non-reducing derivative of inulobiose 3 *D004187 Disaccharides Appl Biochem Biotechnol 1994 Spring;45-46:269-82 PML CCR CCR M0232384 difructose anhydride III C0255826 alpha-D-Fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride 81129-73-9 T262389 difructose anhydride III T262387 DFA III T262388 beta-2,1'-alpha-2',3-difructofuranose anhydride C087827 6-deoxy-6-C-(1,5-di-O-acetyl-2,3-O-isopropylidene-allo-pentofuranos-5-yl)-1,2-3,4-di-O-isopropylidene-galactopyranose 1994 07 18 2001 03 01 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 *D004187 Disaccharides Carbohydr Res 1994 Apr 16;257(1):25-33 PML CCR CCR M0232518 6-deoxy-6-C-(1,5-di-O-acetyl-2,3-O-isopropylidene-allo-pentofuranos-5-yl)-1,2-3,4-di-O-isopropylidene-galactopyranose C0255950 0 T262523 6-deoxy-6-C-(1,5-di-O-acetyl-2,3-O-isopropylidene-allo-pentofuranos-5-yl)-1,2-3,4-di-O-isopropylidene-galactopyranose T262521 6-deoxy-6-C-(1,5-di-O-acetyl-2,3-O-isopropylidene-beta-D-allo-pentofuranos-5-yl)-1,2-3,4-di-O-isopropylidene-alpha-D-galactopyranose T262522 DAIAIG C003058 penicilloyl polylysine 1971 01 01 1993 08 18 1994 1995 1996 1997 1998 1999 2000 2001 2002 15 *PENICILLANIC ACIDS (75-93) *PENICILLINS (73-75) *PEPTIDES (71-75) LYSINE (74-75) D010397 Penicillanic Acid *Q000031 analogs ; derivatives D011107 Polylysine *Q000031 analogs ; derivatives NLM TPW TPW M0043992 penicilloyl polylysine C0070239 53608-77-8 T073995 penicilloyl polylysine C003059 pentaacetyldigitoxin 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *DIGITOXIN (72-75) ACETIC ACIDS (72-75) D000112 Acetyldigitoxins *Q000031 analogs ; derivatives Eur J Clin Pharmacol 12:445;1977 Eur J Clin Pharmacol 13(5):389;1978 NLM NLM M0043993 pentaacetyldigitoxin C0070252 0 T073996 pentaacetyldigitoxin C003028 N-(1-oxyl-2,2,6,6-tetramethyl-4-piperidinyl)iodoacetamide 1971 01 01 2000 12 11 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 22 *PIPERIDINES (71-81) ACETAMIDES (71-75) IODOACETAMIDE/analogs (75-76) *D003497 Cyclic N-Oxides D013113 Spin Labels NLM CCR CCR M0043958 N-(1-oxyl-2,2,6,6-tetramethyl-4-piperidinyl)iodoacetamide C0067431 25713-24-0 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T073961 N-(1-oxyl-2,2,6,6-tetramethyl-4-piperidinyl)iodoacetamide T073954 2,2,6,6-tetramethylpiperdin-N-1-oxyiodoacetamide T073955 4-(2-iodoacetamido)-2,2,6,6-tetramethylpiperidine-1-oxyl T073956 4-(N-iodoacetamide)-2,2,6,6-tetramethylpiperidine-1-oxyl T073958 N-(1-oxy-2,2,6,6-tetramethyl-4-piperidinyl)iodoacetamide T073959 N-(oxyl-2,2,6,6-tetramethylpiperid-4-yl)iodoacetamide T073957 IASL T073960 TMPIA C443129 BF9 chymotrypsin inhibitor 2002 01 08 2002 isolated from Bungarus fasciatus; amino acid sequence in first source 1 *D002038 Bungarotoxins Int J Pept Protein Res 1983 Feb;21(2):209-15 THA THA M0409886 BF9 chymotrypsin inhibitor 0 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance T476532 BF9 chymotrypsin inhibitor 2002 01 08 C003064 pentafluorophenylisothiocyanate 1972 01 01 1982 09 14 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 coupling agent used in Edman degradation 5 FLUOROBENZENES (72-82) *D013861 Thiocyanates Biochim Biophys Acta 257(1):76;1972 NLM VSR NLM M0043996 pentafluorophenylisothiocyanate C0083977 Benzene, pentafluoroisothiocyanato- 35923-79-6 T073999 pentafluorophenylisothiocyanate C003071 perfluorohexylbromide 1974 01 01 1997 05 28 1997 1998 1999 2000 2001 2002 6-carbon perfluorocarbon radiopaque compound 5 *HYDROCARBONS, FLUORINATED (74-77) *D005466 Fluorocarbons Chest 61(2):64S;1972 J Comput Assist Tomogr 1979;3(5):622 NLM TBT NLM M0043999 perfluorohexylbromide C0070399 335-56-8 T074002 perfluorohexylbromide C003073 perfluoromethylcyclohexane 1973 01 01 1982 10 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CYCLOHEXANES (75-82) *HYDROCARBONS, FLUORINATED (74-76) *D005466 Fluorocarbons Br J Anaesth 44(11):1119;1972 NLM VSR NLM M0044013 perfluoromethylcyclohexane C0601701 355-02-2 T074016 perfluoromethylcyclohexane C087830 6-C-(benzyl 5-deoxy-2,3-O-isopropylidene-ribofuranosid-5-yl)-1,2-3,4-di-O-isopropylidene-glycero-galacto-hexopyranose 1994 07 18 2001 03 01 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 *D004187 Disaccharides Carbohydr Res 1994 Apr 16;257(1):25-33 PML CCR CCR M0232525 6-C-(benzyl 5-deoxy-2,3-O-isopropylidene-ribofuranosid-5-yl)-1,2-3,4-di-O-isopropylidene-glycero-galacto-hexopyranose C0255957 0 T262530 6-C-(benzyl 5-deoxy-2,3-O-isopropylidene-ribofuranosid-5-yl)-1,2-3,4-di-O-isopropylidene-glycero-galacto-hexopyranose T262528 6-C-(benzyl-5-deoxy-2,3-O-isopropylidene-beta-D-ribofuranosid-5-yl)-1,2-3,4-di-O-isopropylidene-D-glycero-alpha-D-galacto-hexopyranose T262529 BDIRIG C443130 siglec-F protein, mouse 2002 01 08 2002 GenBank AF293371 1 *D015214 Antigens, Differentiation, Myelomonocytic Microbiology 2001 Nov;147(Pt 11):45128-36 THA THA M0409887 siglec-F protein, mouse 0 T116 Amino Acid, Peptide, or Protein T129 Immunologic Factor T476533 siglec-F protein, mouse 2002 01 08 T476534 mSiglec-F 2002 01 08 C003089 phenylacetylglutamine 1972 01 01 1982 08 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 28 *GLUTAMINE (72-75) PHENYLACETATES (72-82) D005973 Glutamine *Q000031 analogs ; derivatives J Toxicol Environ Health 2(2):459;1976 Soc Biol 18:S26;1971 Zh Nervopatol Psikhiatr 1979;79(10):1324 NLM ESH NLM M0044036 phenylacetylglutamine C0070627 28047-15-6 T074039 phenylacetylglutamine C003092 1-phenyl-1-(2',5'-dimethoxyphenyl)-3-piperidinobutanol 1972 01 01 1998 06 01 1998 1999 2000 2001 2002 RN given refers to HCl 0 *ALCOHOLS, BUTYL (72-82) *D010880 Piperidines Arch Int Pharmacodyn 193(2):372;1971 NLM BQV NLM M0044038 1-phenyl-1-(2',5'-dimethoxyphenyl)-3-piperidinobutanol C0044585 858-68-4 T074041 1-phenyl-1-(2',5'-dimethoxyphenyl)-3-piperidinobutanol C003096 alpha-phenylglutarimide 1973 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 metabolite of glutethimide; structure 0 *PIPERIDIONES (73-79) BENZENE DERIVATIVES (75-76) D005984 Glutethimide *Q000031 analogs ; derivatives Biochem Med 6(2):127;1972 NLM VSR NLM M0044039 alpha-phenylglutarimide C0601706 14149-34-9 T074042 alpha-phenylglutarimide C013626 nojirimycin 1977 01 01 2000 08 03 1995 1996 1997 1998 1999 2000 2000A 2001 2002 from Streptomyces ficellus; RN given refers to parent cpd without isomeric designation 29 *GLUCOSAMINE(76-91) D005944 Glucosamine *Q000031 analogs ; derivatives D013393 Sucrase Q000037 antagonists ; inhibitors Biochim Biophys Acta 525(1):142;1978 J Antibiot (Tokyo) 29(10):1007;1976 J Biochem 81:1017;1977 NLM CCR CCR M0061539 nojirimycin C0068918 15218-38-9 T118 Carbohydrate T195 Antibiotic D000900 Antibiotics D004791 Enzyme Inhibitors 19130-94-0 ((alpha)-isomer) 26360-82-7 (sulfite[1:1]) 62770-70-1 (sulfate[2:1]) M0061539 M0312249 M0061539 M0061538 M0061539 M0312251 M0061539 M0312250 T091542 nojirimycin M0312249 nojirimycin, (alpha)-isomer C0889372 19130-94-0 T118 Carbohydrate T195 Antibiotic M0061539 M0312249 T342249 nojirimycin, (alpha)-isomer 1999 08 18 M0061538 5-amino-D-glucose C0098141 T118 Carbohydrate M0061539 M0061538 T091541 5-amino-D-glucose M0312251 nojirimycin sulfate (2:1) C0889374 62770-70-1 T118 Carbohydrate T195 Antibiotic M0061539 M0312251 T342251 nojirimycin sulfate (2:1) 1999 08 18 M0312250 nojirimycin sulfite (1:1) C0889373 26360-82-7 T118 Carbohydrate T195 Antibiotic M0061539 M0312250 T342250 nojirimycin sulfite (1:1) 1999 08 18 C003104 2-(4-phenyl-1-piperazinylmethyl)cyclohexanone 1972 01 01 1997 08 14 1998 1999 2000 2001 2002 0 *CYCLOHEXANE (72-75) *D003512 Cyclohexanones *D010879 Piperazines D003665 Decompression Sickness Q000188 drug therapy Aerosp Med 42(8):837;1971 NLM MLH TPW M0044045 2-(4-phenyl-1-piperazinylmethyl)cyclohexanone C0601708 735-78-4 T074048 2-(4-phenyl-1-piperazinylmethyl)cyclohexanone C065288 WP 871 1990 09 11 2001 08 17 1999 2000 2001 2001A 2002 leukotriene D4 antagonist 2 *D013777 Tetrazoles Allergy 1990;45(4):249 TPW TWD TWD M0179568 WP 871 C0642376 Acetic acid, oxo((3-(1H-tetrazol-5-yl)phenyl)amino)- 114607-46-4 M0179568 M0179565 T209573 WP 871 T209571 WP-871 T209572 WP871 M0179565 3-(1H-tetrazol-5-yl)oxanilic acid C0642373 M0179568 M0179565 T209570 3-(1H-tetrazol-5-yl)oxanilic acid C043278 indolizomycin 1985 02 05 2001 08 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 isolated from Streptomyces griseus and S. tenjimarienis; structure given in first source 1 D007212 Indolizines J Antibiot (Tokyo) 1984;37(11):1491 MGR jmp jmp M0127435 indolizomycin C0622694 6bH-Cycloprop(a)oxireno(g)indolizin-6b-ol, octahydro-5-(5-methyl-1,3,5-heptatrienyl)- 94935-24-7 T109 Organic Chemical T195 Antibiotic T157440 indolizomycin T157439 (1S,2R,3S,7R,8R)-7,8-epoxy-8a-hydroxy-1,2-dimethylene-3-(1E,3E,5E)-(5-methyl-1,3,5-heptatrienyl)octahydroindolizine C001416 deterenol 1971 01 01 2001 08 17 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2000B 2001 2001A 2002 RN given refers to parent cpd without isomeric designation; structure 3 *AMINO ALCOHOLS (71-73) *ETHANOLAMINES (73-79) PHENOLS (73-76) PROPYLAMINES (73-76) D009655 Octopamine *Q000031 analogs ; derivatives NLM CCR CCR M0041592 deterenol C0057574 4-hydroxy-alpha-(((1-methylethyl)amino)methyl)benzenemethanol 7376-66-1 T109 Organic Chemical T121 Pharmacologic Substance 23239-36-3 (HCl(+-)-isomer) 3506-31-8 ((+-)-isomer) 51542-07-5 (unspecified sulfate salt) 7104-41-8 (sulfate(1:1)) 76166-70-6 (oxalate(2:1)(+-)-isomer) M0041592 M0041587 M0041592 M0307628 M0041592 M0307629 M0041592 M0307632 M0041592 M0307631 M0041592 M0041588 M0041592 M0041589 M0041592 M0041590 T071595 deterenol Negwer #57N - HCl USAN 1978 - HCl, p. 97 T071589 1-(4-hydroxyphenyl)-2-isopropylaminoethanol M0041587 AL 842 C0101995 T109 Organic Chemical T121 Pharmacologic Substance M0041592 M0041587 T071590 AL 842 M0307628 deterenol hydrochloride, (+-)-isomer C0888056 23239-36-3 T109 Organic Chemical T121 Pharmacologic Substance M0041592 M0307628 T337628 deterenol hydrochloride, (+-)-isomer 1999 08 18 M0307629 deterenol, (+-)-isomer C0888057 3506-31-8 T109 Organic Chemical T121 Pharmacologic Substance M0041592 M0307629 T337629 deterenol, (+-)-isomer 1999 08 18 M0307632 deterenol oxalate (2:1), (+-)-isomer C0951044 76166-70-6 T109 Organic Chemical T121 Pharmacologic Substance M0041592 M0307632 T337632 deterenol oxalate (2:1), (+-)-isomer 1999 08 18 M0307631 deterenol sulfate (1:1) C0951043 7104-41-8 T109 Organic Chemical T121 Pharmacologic Substance M0041592 M0307631 T337631 deterenol sulfate (1:1) 1999 08 18 M0041588 N-isopropylnorsynephrine C0131209 T109 Organic Chemical T121 Pharmacologic Substance M0041592 M0041588 T071591 N-isopropylnorsynephrine M0041589 N-isopropyloctopamine C0131210 T109 Organic Chemical T121 Pharmacologic Substance M0041592 M0041589 T071592 N-isopropyloctopamine M0041590 PI 39 C0137001 T109 Organic Chemical T121 Pharmacologic Substance M0041592 M0041590 T071593 PI 39 T071594 PI-39 C020616 dihydroergovaline 1979 01 01 2001 08 17 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd 0 *D004877 Ergoloid Mesylates Med Welt 30(31-32):1166;1979 NLM CCR CCR M0074497 dihydroergovaline C0608600 (5' alpha)-9,10-dihydro-12'-hydroxy-2'- methyl-5'-(1-methylethyl)ergotaman-3',6',18-trione 3036-37-1 65842-80-0 (methanesulfonate salt) M0074497 M0314236 T104500 dihydroergovaline M0314236 dihydroergovaline methanesulfonate C0953045 65842-80-0 M0074497 M0314236 T344236 dihydroergovaline methanesulfonate 1999 08 18 C050815 phenylalanyl-prolyl-arginine chloromethyl ketone-thrombin 1987 01 05 2001 01 19 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 12 THROMBIN/*analogs (87-89) *D000590 Amino Acid Chloromethyl Ketones *D013917 Thrombin J Biol Chem 1986;261(34):15928 MEG WXM WXM M0144900 phenylalanyl-prolyl-arginine chloromethyl ketone-thrombin C0070656 0 T174905 phenylalanyl-prolyl-arginine chloromethyl ketone-thrombin T174902 Phe-Pro-Arg-AACK-thrombin T174903 Phe-Pro-Arg-chloromethyl ketone-thrombin T174901 PPACK-thrombin T174904 thrombin-Phe-Pro-Arg-AACK C098738 N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone 1996 04 26 2001 01 19 1997 1998 1999 2000 2001 2001A 2002 83 *D000590 Amino Acid Chloromethyl Ketones Biochem J 1996 Feb 15;314(Pt 1):27-32 PML WXM WXM M0259323 N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone C0388131 0 D015853 Cysteine Proteinase Inhibitors T289328 N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone T289322 Ac-Tyr-Val-Ala-Asp-CMK T289323 Ac-YVAD-cmk T289324 N-acetyl-tyrosinyl-valinyl-alanyl-aspartyl chloromethyl ketone T289325 N-acetyltyrosinylvalinylalanylaspartylchloromethyl ketone T289327 YVAD-chloromethylketone T289326 YVAD-CMK C089281 2,2',3,3'-tetra-O-acetyl-4,4',6,6'-tetradeoxyxylotrehalose 1994 10 05 2001 03 01 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 *D004187 Disaccharides Acta Crystallogr C 1994 Jul 15;50(Pt 7):1108-12 PML CCR CCR M0236090 2,2',3,3'-tetra-O-acetyl-4,4',6,6'-tetradeoxyxylotrehalose C0258981 0 T266095 2,2',3,3'-tetra-O-acetyl-4,4',6,6'-tetradeoxyxylotrehalose T266093 2,2',3,3'-tetraacetyl-4,4',6,6'-tetradeoxy-alpha,alpha-xylo-trehalose T266094 TATD-xylo-trehalose C103192 butyloxycarbonyl-O-methyl-aspartyl-fluoromethyl ketone 1997 01 25 2001 01 19 1999 2000 2001 2001A 2002 30 *D000590 Amino Acid Chloromethyl Ketones D020169 Caspases Q000037 antagonists ; inhibitors J Exp Med 1996 Dec 1;184(6):2445-50 BMB WXM WXM M0269887 butyloxycarbonyl-O-methyl-aspartyl-fluoromethyl ketone C0533362 0 D015853 Cysteine Proteinase Inhibitors T299892 butyloxycarbonyl-O-methyl-aspartyl-fluoromethyl ketone T299890 Boc-Asp(OMe)-FMK T299891 boc-aspartyl(OMe)-fluoromethylketone C046071 retinol-binding protein (type 2) 1985 08 23 2001 01 19 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 found mainly in cells of small intestine; different from cellular retinol binding protein (= RETINOL BINDING PROTEINS) 63 *D012177 Retinol-Binding Proteins Proc Natl Acad Sci USA 1985;82(14):4707 RLS TWD TWD M0133653 retinol-binding protein (type 2) C0073118 0 T163658 retinol-binding protein (type 2) T163657 CRBP (II) C003143 4,4'-(2-picolylidene)bis(phenylphosphoric acid) 1972 01 01 1982 10 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PICOLINE (72-75) PICOLINES/*analogs (79-82) *D009943 Organophosphorus Compounds Arzneim Forsch 22(3):531;1972 NLM VSR NLM M0044113 4,4'-(2-picolylidene)bis(phenylphosphoric acid) C0601717 0 T074116 4,4'-(2-picolylidene)bis(phenylphosphoric acid) C003147 pinacolyl S-(2-dimethylaminoethyl)methylphosphonothioate 1972 01 01 1981 11 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ETHYLAMINES (72-76) GLYCOLS (73-75) *D009946 Organothiophosphorus Compounds J Neurochem 18(12):2329;1971 NLM NBM NLM M0044116 pinacolyl S-(2-dimethylaminoethyl)methylphosphonothioate C0071078 34388-36-8 T074119 pinacolyl S-(2-dimethylaminoethyl)methylphosphonothioate C073649 (tetrazol-5-yl)glycine 1992 04 20 2001 08 17 1997 1998 1999 2000 2001 2001A 2002 potent NMDA receptor agonist; structure given in first source 11 *D013777 Tetrazoles D005998 Glycine *Q000031 analogs ; derivatives D016202 N-Methylaspartate Q000819 agonists Eur J Pharmacol 1991 Oct 15;203(2):237-43 RLS TWD TWD M0199035 (tetrazol-5-yl)glycine C0166351 138199-51-6 M0199035 M0199032 T229040 (tetrazol-5-yl)glycine T229039 tetrazol-5-yl-Gly M0199032 LY 285 265 C0527093 M0199035 M0199032 T229037 LY 285 265 T229038 LY-285,265 C119788 dodecaborate 1999 07 02 2001 08 17 1999 2000 2000A 2000B 2001 2001A 2002 RN given for disodium salt; structure in first source 1 *D001896 Boron Compounds Bioconj Chem 1999 May-Jun;10(3):338-45 THA CCR CCR M0306532 dodecaborate C0768812 12008-78-5 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid 12008-75-2 (di-Cs salt) 26023-72-3 (duplicate RN, di-Na salt) M0306532 M0306531 M0306532 M0327934 T336537 dodecaborate M0306531 closo-dodecaborate(2-) C0768811 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0306532 M0306531 T336536 closo-dodecaborate(2-) M0327934 dodecaborate, dicesium salt C0970949 12008-75-2 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0306532 M0327934 T357934 dodecaborate, dicesium salt 1999 08 18 C003152 piperidyl-2-glycolic acid ethyl ester 1971 01 01 1982 09 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 PIPERIDINES (71-82) *D006016 Glycolates NLM VSR NLM M0044127 piperidyl-2-glycolic acid ethyl ester C0601723 0 T074130 piperidyl-2-glycolic acid ethyl ester C003254 flavazole 1972 01 01 2001 01 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN from 9th CI, Chem Subs Index 0 *D011720 Pyrazoles *D011810 Quinoxalines Eur J Immun 1(2):106;1971 NLM TWD TWD M0044244 flavazole C0601750 269-75-0 T074247 flavazole T074246 pyrazolo(3,4-b)quinoxaline C073705 prosystemin 1992 04 22 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; a 200 amino acid precursor protein of systemin; from Lycopersicon esculentum (tomato) 16 *D010940 Plant Proteins Science 1992 Mar 20;255(5051):1570-3 BXB WXM WXM M0199194 prosystemin C0166472 146991-19-7 T229199 prosystemin T229198 prosystemin gene product C003243 psicose 1973 01 01 2000 07 31 2001 2002 C-3 epimer of D-fructose in Chemline; RN given refers to cpd without isomeric designation 5 *D005632 Fructose Carbohydr Res 20(1):170;1971 Ugeskr Laeger 139(11):647;1977 NLM CCR sjn M0044230 psicose C0072565 23140-52-5 T118 Carbohydrate 16354-64-6 ((L)-isomer) 551-68-8 ((D)-isomer) M0044230 M0308225 M0044230 M0308224 T074233 psicose T074232 allulose M0308225 psicose, (D)-isomer C0112154 551-68-8 T118 Carbohydrate M0044230 M0308225 T338225 psicose, (D)-isomer 1999 08 18 T074229 D-psicose T074230 D-ribo-2-hexulose T074231 D-ribo-2-ketohexose M0308224 psicose, (L)-isomer C0894395 16354-64-6 T118 Carbohydrate M0044230 M0308224 T338224 psicose, (L)-isomer 1999 08 18 C073759 multifunctional beta-oxidation protein, Saccharomyces 1992 04 25 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 proteins contains 900 amino acids, MW 96kDa; amino acid given in first source 1 *D005656 Fungal Proteins J Biol Chem 1992 Apr 5;267(10):6646-53 RLS WXM WXM M0199322 multifunctional beta-oxidation protein, Saccharomyces C0650689 146835-48-5 T229327 multifunctional beta-oxidation protein, Saccharomyces T229326 MFBOP, Sacch C003171 polyacetalcarboxylate 1974 01 01 1982 09 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 CARBOXYLIC ACIDS (74-76) POLYMERS (74-82) *D000080 Acetals NLM VSR NLM M0044146 polyacetalcarboxylate C0601724 0 T074149 polyacetalcarboxylate C003175 polychlorobutane 1974 01 01 1983 08 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D006843 Hydrocarbons, Chlorinated *D011108 Polymers NLM DLJ NLM M0044151 polychlorobutane C0601727 0 T074154 polychlorobutane C003188 3-polyprenyl-4-hydroxybenzoate 1972 01 01 1982 08 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *BENZOATES (72-75) *HYDROXYBENZOIC ACIDS (75-82) PHENOLS (73-75) *D013729 Terpenes J Biol Chem 247(12):3930;1972 NLM VSR NLM M0044168 3-polyprenyl-4-hydroxybenzoate C0047705 0 T074171 3-polyprenyl-4-hydroxybenzoate C003196 popiodol suspension 1972 01 01 1997 05 28 1997 1998 1999 2000 2001 2002 contains iodized poppy seed oil, surfactant, glucose 0 *D005947 Glucose *D007459 Iodized Oil *D013501 Surface-Active Agents D004338 Drug Combinations Nippon Igaku Hoshasen Gakkai Zasshi 31(10):1083;1972 NLM TBT TPW M0044172 popiodol suspension C0601729 0 T074175 popiodol suspension C003204 Predni-opthiole 1972 01 01 1982 09 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D002701 Chloramphenicol *D011241 Prednisone D004338 Drug Combinations D009883 Ophthalmic Solutions NLM VSR NLM M0044175 Predni-opthiole C0601732 0 T074178 Predni-opthiole C003208 Preparyl 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination drug containing Cetiprin, Recipavrin ; amobarbital 0 *AMMONIUM CPDS (72-75) *D000654 Amobarbital *D004629 Emepronium *D011437 Propylamines D004338 Drug Combinations Scand J Infect Dis 1(2):209;1969 NLM NLM M0044176 Preparyl C0601733 Benzenepropanaminium, N-ethyl-N,N,alpha-trimethyl-gamma-phenyl-, bromide, mixt. with 5-ethyl-5-(3-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione and N,N,alpha-trimethyl-gamma-phenylbenzenepropanamine 8061-70-9 T074179 Preparyl C003215 prolinomethyltetracycline 1972 01 01 1982 09 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *TETRACYCLINE (72-76) PROLINE (72-75) PROLINE/analogs (75-82) *D013754 Tetracyclines Jpn J Antibiot 24(6):249;1971 NLM VSR NLM M0044191 prolinomethyltetracycline C0601740 37106-99-3 T074194 prolinomethyltetracycline Negwer, 5th ed, #5667 C093812 divergicin A 1995 06 29 2000 07 31 2001 2002 a signal peptide secretion-dependent bacteriocin; produced by Carnobacterium divergens LV13; amino acid sequence given in first source; GenBank L37791 6 *D001430 Bacteriocins D021382 Protein Sorting Signals J Bacteriol 1995 Jun;177(11):3143-9 PML nns sjn M0247283 divergicin A C0298007 0 T116 Amino Acid, Peptide, or Protein T195 Antibiotic T277288 divergicin A T277287 dvnA gene product C003235 proxifezone 1971 01 01 1989 08 04 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains equimolecular amounts of dextro-propoxyphene ; phenylbutazone 0 *D010653 Phenylbutazone *D011431 Propoxyphene D004338 Drug Combinations NLM RJM RLS M0044216 proxifezone C0601743 34427-79-7 T074219 proxifezone Negwer, 5th ed, #3906-04 USAN 1980, p.272 C003239 pseudoangiotensin II 1972 01 01 1986 01 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D000804 Angiotensin II Horm Metab Res 4(3):210;1972 NLM PEH NLM M0044224 pseudoangiotensin II C0601746 37221-35-5 T074227 pseudoangiotensin II C010258 enprofen 1975 01 01 2000 07 31 2001 2002 RN given refers to parent cpd; structure 1 PROPIONIC ACIDS (75-82) *D001572 Benzofurans Arch Int Pharmacodyn Ther 214(2):240;1975 J Clin Pharmacol 16(10):473;1976 NLM WXM sjn M0055625 enprofen C0059371 alpha-methyl-3-phenyl-7-benzofuranacetic acid 37664-95-2 T109 Organic Chemical T121 Pharmacologic Substance 67700-30-5 ((+-)-isomer) M0055625 M0311083 M0055625 M0055624 T085628 enprofen USAN 1980, p. 123 M0311083 enprofen, (+-)-isomer C0896063 67700-30-5 T109 Organic Chemical T121 Pharmacologic Substance M0055625 M0311083 T341083 enprofen, (+-)-isomer 1999 08 18 M0055624 R-803 C0139820 0 T109 Organic Chemical T121 Pharmacologic Substance M0055625 M0055624 T085627 R-803 C411199 N-acetyl-hydroxyvaline lactone 2000 07 26 2000 2001 2002 an unusual amino acid derivative from a marine streptomycete; structure in first source 1 *D007783 Lactones D014633 Valine *Q000031 analogs ; derivatives J Nat Prod 2000 May;63(5):664-5 BMB BMB M0366651 N-acetyl-hydroxyvaline lactone C0915925 0 T109 Organic Chemical T116 Amino Acid, Peptide, or Protein T420002 N-acetyl-hydroxyvaline lactone 2000 07 26 T420003 N-acetyl-gamma-hydroxyvaline lactone 2000 07 26 T420004 N-Ac-H-Val-L 2000 07 26 C003245 puricilina 1972 01 01 1991 10 01 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination of penimepicycline ; bromelina 0 *TETRACYCLINE (72-76) *D001963 Bromelains *D010404 Penicillin V *D013754 Tetracyclines D004338 Drug Combinations Prensa Med Argent 59(17):671;1972 NLM AJC TPW M0044231 puricilina C0601747 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenoxyacetyl)amino)-, (2S-(2alpha,5alpha,6beta))-, compd. with (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-N-((4-(2-hydroxyethyl)-1-piperazinyl)methyl)-6-methyl-1,11-dioxo-2-naphthacenecarboxamide (1:1), mixt. with bromelain juice 78515-89-6 T074234 puricilina C051021 DTPP vaccine 1987 01 20 2000 07 31 2001 2002 36 DRUG COMBINATIONS (87-95) *D004168 Diphtheria Toxoid *D010567 Pertussis Vaccine *D011054 Poliovirus Vaccine, Inactivated *D013745 Tetanus Toxoid *D015721 Diphtheria-Tetanus-Pertussis Vaccine D017778 Vaccines, Combined Am J Dis Child 1987;141(1):14 RLS nns sjn M0145407 DTPP vaccine C0058782 0 T121 Pharmacologic Substance T129 Immunologic Factor T175412 DTPP vaccine T175411 diphtheria-tetanus-pertussis-poliovirus vaccine C038476 DTTAB vaccine 1983 08 02 2000 07 31 2001 2002 3 *DIPHTHERIA TOXOID (1996-2000) *TETANUS TOXOID (1996-2000) DRUG COMBINATIONS (1983-1995) *D014436 Typhoid-Paratyphoid Vaccines *D022422 Diphtheria-Tetanus Vaccine D017778 Vaccines, Combined Presse Med 1983;12(25):1587 MEG nns sjn M0115798 DTTAB vaccine C0058783 0 T121 Pharmacologic Substance T129 Immunologic Factor T145802 DTTAB vaccine T145801 diphtheria-tetanus-typhoid-paratyphoid vaccine C073788 dctD protein 1992 04 27 2001 01 30 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; involved in transport of C4-dicarboxylic acids; controls dctA expression 19 *CARRIER PROTEINS (92-94) *D014157 Transcription Factors D001426 Bacterial Proteins D016962 Sinorhizobium meliloti Mol Plant Microbe Interact 1990 May-Jun;3(3):174-81 BXB WXM WXM M0199400 dctD protein C0166647 147953-38-6 T229405 dctD protein T229404 dctD gene product C003255 pyrethrosin 1972 01 01 1981 11 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 *PYRETHRUM (72-77) LACTONES (72-81) *D011722 Pyrethrins Br J Dermatol 86(6):568;1972 NLM NBM NLM M0044245 pyrethrosin C0601751 28272-18-6 T074248 pyrethrosin Merck, 9th ed, #7748 C003347 4-stilbazole 1972 01 01 2001 07 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 2 *D011725 Pyridines *D013343 Styrenes J Med Chem 15(6):193;1972 NLM CCR CCR M0044384 4-stilbazole C0048705 103-31-1 10129-69-8 (mono-HCl salt) 19337-93-0 (mono-HCl salt(E)-isomer) 5097-92-7 ((Z)-isomer) 5097-93-8 ((E)-isomer) M0044384 M0308271 M0044384 M0308270 M0044384 M0044383 M0044384 M0308268 M0044384 M0308269 T074387 4-stilbazole Merck Index, 9th ed, #8599 M0308271 4-stilbazole, (E)-isomer C0969871 5097-93-8 M0044384 M0308271 T338271 4-stilbazole, (E)-isomer 1999 08 18 M0308270 4-stilbazole, (Z)-isomer C0951178 5097-92-7 M0044384 M0308270 T338270 4-stilbazole, (Z)-isomer 1999 08 18 M0044383 4-styrylpyridine C0097498 M0044384 M0044383 T074386 4-styrylpyridine M0308268 4-stilbazole monohydrochloride C0951176 10129-69-8 M0044384 M0308268 T338268 4-stilbazole monohydrochloride 1999 08 18 M0308269 4-stilbazole monohydrochloride, (E)-isomer C0951177 19337-93-0 M0044384 M0308269 T338269 4-stilbazole monohydrochloride, (E)-isomer 1999 08 18 C043437 fluorodopa F 18 1984 12 14 2001 07 17 1998 1999 2000 2001 2001A 2001B 2002 RN given refers to (L)-isomer 276 D004295 Dihydroxyphenylalanine *Q000031 analogs ; derivatives D005462 Fluorine Radioisotopes J Nucl Med 1984;25(11):1228 RLS TWD TWD M0127845 fluorodopa F 18 C0244672 75290-51-6 92812-82-3 ((18)F-labeled cpd) T157850 fluorodopa F 18 USAN (1990) T157843 (18)F-dopa T157844 2-fluoro-5-hydroxytyrosine T157845 3,4-dihydroxy-6-fluorophenylalanine T157846 3-(2-fluoro-(18)F-4,5-dihydroxyphenyl)-L-alanine T157848 6-fluoro-DOPA T438296 6-(18F)fluoro-L-DOPA 2001 03 07 T157849 6-fluorodopa T157847 6-(18F)fluoro-L-3,4-dihydroxyphenylalanine T351912 fluorodopa F 18, (18)F-labeled cpd 1999 08 18 C008675 nordopan glucoside 1974 01 01 2001 07 17 1998 1999 2000 2001 2001A 2002 Russian drug; RN given refers to (beta-D)-isomer; structure 0 *URACIL MUSTARD (74-75) GLUCOSIDES (75-82) PYRIMIDINE NUCLEOSIDES (74-75) D014499 Uracil Mustard *Q000031 analogs ; derivatives Biull Eksp Biol Med 75(5):73;1973 NLM jmp jmp M0052724 nordopan glucoside C0603668 41622-07-5 T109 Organic Chemical T121 Pharmacologic Substance 41622-06-4 ((alpha-D)-isomer) M0052724 M0310399 T082727 nordopan glucoside T082726 N(1)-(beta-D-glucopyranosyl)-5-(bis-(2-chloroethyl)amino)uracil M0310399 nordopan glucoside, (alpha-D)-isomer C0951902 41622-06-4 T109 Organic Chemical T121 Pharmacologic Substance M0052724 M0310399 T340399 nordopan glucoside, (alpha-D)-isomer 1999 08 18 C003275 Rofenaid 1972 01 01 1984 08 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination drug containing ormetoprim ; sulfadimethoxine 1 *PYRIMIDINES (72-75) *D011743 Pyrimidines *D013412 Sulfadimethoxine D004338 Drug Combinations J Agr Food Chem 19(6):1260;1971 NLM GTC NLM M0044279 Rofenaid C0073557 8076-37-7 T074282 Rofenaid USAN 1978, p.274 C003289 rabelomycin 1970 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 D000880 Anthraquinones J Antibiot (Tokyo) 23(9):437;1970 NLM VSR NLM M0044303 rabelomycin C0376748 28399-50-0 T074306 rabelomycin C003294 requinomycin 1972 01 01 1995 09 19 1996 1997 1998 1999 2000 2001 2002 anthracycline antibiotic 0 *ANTHRACENES (72-79) *ANTIBIOTICS, ANTHRACYCLINE (89-95) NAPHTHACENES (72-88) D018943 Anthracyclines J Antibiot (Tokyo) 25(7):393;1972 NLM PML BVL M0044307 requinomycin C0073077 12770-40-0 T074310 requinomycin C044171 endodeoxyribonuclease BSSHII 1985 02 28 2001 07 17 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from Bacillus stearothermophilus; a type II site-specific endonuclease EC 3.1.21.4; recognizes ; cleaves the sequence G/CGCGC 23 *DNA RESTRICTION ENZYMES (85-88) *D015252 Deoxyribonucleases, Type II Site-Specific J Bacteriol 1985;161(1):60 MEG jmp jmp M0129205 endodeoxyribonuclease BSSHII C0059143 EC 3.1.21.- T116 Amino Acid, Peptide, or Protein T126 Enzyme M0129205 M0129204 T159210 endodeoxyribonuclease BSSHII T159208 BSSHII endonuclease M0129204 BsePI endonuclease C0107309 T116 Amino Acid, Peptide, or Protein T126 Enzyme M0129205 M0129204 T159209 BsePI endonuclease C003301 rhazidine 1972 01 01 1981 06 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 alkaloid from Rhazya stricta; structure 0 INDOLES (72-81) *D000470 Alkaloids Aust J Exp Biol Med Sci 49(4):397;1971 NLM NBM NLM M0044323 rhazidine C0601765 15381-61-0 T074326 rhazidine C003417 tetranactin 1971 01 01 2001 01 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from Streptomyces strain S-3466; miticidal; structure 10 *ANTIBIOTICS (71-79) *D011714 Pyrans Ann NY Acad Sci 264:34;1975 Biopolymers 14(5):1049;1975 Environ Qual Saf 5:53;1976 J Antibiot (Tokyo) 27(7):555;1974 J Membr Biol 30(1):1;1976 J Pharm Soc Jpn 97(1):46;1977 NLM TWD TWD M0044464 tetranactin C0076315 33956-61-5 T109 Organic Chemical T121 Pharmacologic Substance T074467 tetranactin C003313 sinalbin 1973 01 01 1982 08 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 3 *CHOLINE (73-75) *CINNAMATES (73-76) *GLUCOSINOLATES (79-82) *GLYCOSIDES (73-75) *THIOGLUCOSIDES (75-79) D002794 Choline *Q000031 analogs ; derivatives J Agric Food Chem 1980;28(1):43 J Sci Food Agric 27:438;1976 Mikrochim Acta 6(0):818;1972 NLM ESH NLM M0044336 sinalbin C0074556 20196-67-2 M0044336 M0044335 T074339 sinalbin Merck Index, 9th ed, #8287 M0044335 sinapine p-hydroxybenzylglucosinolate C0142335 M0044336 M0044335 T074338 sinapine p-hydroxybenzylglucosinolate C003317 sodium 4-(2-acetamidoethyldithio)butanesulfinate 1972 01 01 1983 08 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ACETAMIDES (72-82) *DISULFIDES (72-76) *SULFINIC ACIDS (72-76) *D002073 Butanes J Med Chem 15(3):312;1972 NLM ACS NLM M0044342 sodium 4-(2-acetamidoethyldithio)butanesulfinate C0601768 19293-56-2 T074345 sodium 4-(2-acetamidoethyldithio)butanesulfinate C041392 flumethrin 1984 07 06 2001 01 11 1995 1996 1997 1998 1999 2000 2001 2001A 2002 synthetic pyrethrin insecticide 53 *D011722 Pyrethrins Zentralbl Veterinarmed (B) 1984;31(3):161 MEG TWD TWD M0122757 flumethrin C0060495 69770-45-2 T109 Organic Chemical T131 Hazardous or Poisonous Substance T152762 flumethrin Merck Index 10th ed, #A6 T152761 alpha-cyano-(4-fluoro-3-phenoxy)benzyl-3-(2-chloro-2-(4-chlorophenyl)ethenyl)-2,2-dimethylcyclopropanecarboxylate C003299 N-retinylidene-n-butylamine 1972 01 01 2001 01 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 3 *BUTYLAMINES (72-81) VITAMIN A/*analogs (81-83) *D012176 Retinoids D012168 Retinal Pigments Biochemistry 11(5):848;1972 Biochemistry 14(11):2304;1975 J Am Chem Soc 99(17):5592;1977 NLM TWD TWD M0044320 N-retinylidene-n-butylamine C0068282 1-Butanamine, N-(3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenylidene)-, (E,E,E,E)- 36076-04-7 T074323 N-retinylidene-n-butylamine T074322 retinyl-BA C003343 stellacyanin 1970 01 01 1983 07 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 copper containing protein from Rhus vernicifera 41 COPPER (74-76) *D008667 Metalloproteins *D010940 Plant Proteins Biochem Biophys Res Commun 77(3):1052;1977 Biochem Soc Trans 7(4):733;1979 Biochemistry 15(17):3863;1976 Biochimie 1979;61(7):781 Bioinorg Chem 8(5):369;1978 Eur J Biochem 84:207;1978 J Am Chem Soc 99(15):5158;1977 J Biol Chem 254(11):4321;1979 J Inorg Biochem 1979;11(2):101 J Inorg Biochem 1979;11(2):95 Proc Natl Acad Sci USA 71(4):1339;1974 Proc Natl Acad Sci USA 73(5):1389;1976 NLM ACS NLM M0044378 stellacyanin C0075217 Stellacyanins 12738-61-3 T074381 stellacyanin C003345 sterculic acid 1970 01 01 1987 07 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 9 *FATTY ACIDS (70-73) *FATTY ACIDS, UNSATURATED (73-87) CYCLOPROPANES (75-80) *D003521 Cyclopropanes *D005229 Fatty Acids, Monounsaturated Biochim Biophys Acta 488:76;1977 Exp Mol Pathol 23:164;1975 Lipids 12(6):480;1977 Science 185(4154):958;1974 Science 1980;208(4441):309 NLM DLV NLM M0044381 sterculic acid C0075229 738-87-4 T074384 sterculic acid C056435 endodeoxyribonuclease ApaLI 1988 08 04 2001 07 17 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 type II restriction endonuclease, EC 3.1.21.4 14 *DNA RESTRICTION ENZYMES (88) *D015252 Deoxyribonucleases, Type II Site-Specific Nucleic Acids Res 1988;16(11):5206 TPW jmp jmp M0158281 endodeoxyribonuclease ApaLI C0059123 EC 3.1.21.- T116 Amino Acid, Peptide, or Protein T126 Enzyme M0158281 M0158280 T188286 endodeoxyribonuclease ApaLI T188284 ApaLI endonuclease M0158280 SnoI endonuclease C0142759 T116 Amino Acid, Peptide, or Protein T126 Enzyme M0158281 M0158280 T188285 SnoI endonuclease C003348 stimulon 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 interferon antagonist induced by Newcastle disease virus 2 *D014764 Viral Proteins Proc Soc Exp Biol Med 142(1):266;1973 NLM NLM M0044385 stimulon C0162926 0 T074388 stimulon C003354 Sucsan-azulen 1972 01 01 1982 06 23 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains sucsan ; bicyclophenamin 0 *BRIDGED COMPOUNDS (72-75) *PYRROLIDINES (72-75) *D001643 Bicyclo Compounds *D010936 Plant Extracts D004338 Drug Combinations Med Monatschr 26(2):86;1972 NLM ESH NLM M0044390 Sucsan-azulen C0075487 Sucsan, mixt. with azulene 8059-84-5 T074393 Sucsan-azulen C003360 5'-sulfamoyladenosine 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ADENOSINE (72-75) SULFONAMIDES (72-75) D000241 Adenosine *Q000031 analogs ; derivatives Ann NY Acad Sci 255:216;1975 Biochemistry 10(24):4394;1971 NLM NLM M0044398 5'-sulfamoyladenosine C0048842 25030-31-3 T074401 5'-sulfamoyladenosine C073790 ERV1 protein 1992 04 27 2001 01 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; MW 14 kDa; nuclear gene in yeast Essential for Respiration and Viability (ERV) 15 *D005656 Fungal Proteins Mol Gen Genet 1992 Mar;232(1):58-64 BXB WXM WXM M0199402 ERV1 protein C0166649 141933-92-8 T229407 ERV1 protein T229406 ERV1 gene product C003367 sulphoquinovosyl-diacylglycerol 1980 08 08 1982 07 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *GLYCERIDES (72-75) *THIOGLYCOSIDES (80-82) DEOXYGLUCOSE/analogs (75-76) GLUCOSE (72-75) *D004075 Diglycerides Biochim Biophys Acta 398(2):224;1975 Z Naturforsch 25(4):412;1970 TYK ESH NLM M0044407 sulphoquinovosyl-diacylglycerol C0075626 0 M0044407 M0044406 T074410 sulphoquinovosyl-diacylglycerol M0044406 6-sulpho-6-deoxy-alpha-D-glucopyranosyldiglyceride C0099439 M0044407 M0044406 T074409 6-sulpho-6-deoxy-alpha-D-glucopyranosyldiglyceride C121094 SM 20550 1999 10 13 2001 01 30 1999 2000 2001 2001A 2002 inhibits sodium-hydrogen exchanger; protects against myocardial injury and microvascular deterioration after reperfusion; structure in first source 10 *D000578 Amidines *D007211 Indoles Eur J Pharmacol 1999 Jun 25;374(3):355-66 BVL CCR CCR M0334158 SM 20550 C0908595 0 T109 Organic Chemical T121 Pharmacologic Substance M0334158 M0334160 T366252 SM 20550 T366253 SM-20550 M0334160 N-(aminoiminomethyl)-1,4-dimethyl-1H-indole-2-carboxamide methanesulfonate C0908597 M0334158 M0334160 T366254 N-(aminoiminomethyl)-1,4-dimethyl-1H-indole-2-carboxamide methanesulfonate C003370 sureptil 1972 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains cinnarizine ; heptaminol acefyllinate 0 *AMINO ALCOHOLS (72-76) *PIPERAZINES (72-75) *THEOPHYLLINE (72-76) *D002936 Cinnarizine D004338 Drug Combinations D006535 Heptaminol *Q000031 analogs ; derivatives D013806 Theophylline *Q000031 analogs ; derivatives NLM RLS NLM M0044410 sureptil C0075657 7H-Purine-7-acetic acid, 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-, compd. with 6-amino-2-methyl-2-heptanol (1:1), mixt. with 1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)piperazine 79121-49-6 T074413 sureptil UD 20:27f C419104 fibrinogen Osaka VI 2001 01 30 2001 2002 has a 12-residue carboxyl-terminal extension of Lys-Ser-Pro-Met-Arg-Arg-Phe-Leu-Leu-Phe-Cys-Met due to a T-to-A mutation that creates AAG encoding Lys at the stop (TAG) codon, thus translating 36 base pairs in the noncoding region of the Bbeta gene; associated with severe bleeding; 1 *D015241 Fibrinogens, Abnormal Blood. 2000 Dec 1;96(12):3779-85 BMB BMB M0377453 fibrinogen Osaka VI C0963600 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T434553 fibrinogen Osaka VI 2001 01 30 C052570 cyfluthrin 1987 07 27 2001 01 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 effective against mosquitoes 51 *D011722 Pyrethrins Indian J Med Res 1987;85:168 MGR TWD TWD M0149164 cyfluthrin C0056836 68359-37-5 T109 Organic Chemical T131 Hazardous or Poisonous Substance D007309 Insecticides, Organochlorine M0149164 M0149161 T179169 cyfluthrin T179168 cyano(4-fluoro-3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane carboxylate M0149161 OMS 2012 C0133914 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0149164 M0149161 T179166 OMS 2012 T179167 OMS-2012 C003392 tetra-o-cresol phosphate 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 toxic industrial compound causing paralysis 0 *CRESOLS (72-75) *ORGANOPHOSPHORUS COMPOUNDS (73-75) *D014317 Tritolyl Phosphates Ann R Acad Nacl Med 88:295;1971 NLM NLM M0044432 tetra-o-cresol phosphate C0601782 0 T074435 tetra-o-cresol phosphate C003393 tetracyanoethylene 1972 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 9 *D005030 Ethylenes *D009570 Nitriles Acta Biol Med Ger 34(10):1561;1975 Helv Chim Acta 58(3):833;1975 J Vitam 18(1):63;1972 NLM NLM M0044433 tetracyanoethylene C0076241 670-54-2 T074436 tetracyanoethylene C005790 beta-thujone 1972 01 01 2000 07 31 2001 2002 constituent of many essential oils; present in thuja etc.; ingestion may cause convulsions; active principle of Artemisia absinthium; RN given refers to cpd without isomeric designation; structure 18 PLANT EXTRACTS (72-81) *D013729 Terpenes C R Soc Biol (Paris) 170(1):15;1976 J Med Chem 19(8):1054;1976 Nature 253(5490):365;1975 NLM TWD sjn M0047553 beta-thujone C0053509 1125-12-8 T109 Organic Chemical T121 Pharmacologic Substance 471-15-8 (1S-(1alpha,4beta,5alpha)-isomer) 546-80-5 ((1S-(1alpha,4alpha,5alpha)-isomer) 59573-80-7 ((1alpha,4alpha,5alpha)-isomer) M0047553 M0309292 M0047553 M0309291 M0047553 M0309290 T077556 beta-thujone Merck, 9th ed, #9133 T077553 3-isothujone T077554 3-thujanone T077555 thujone M0309292 beta-thujone, (1alpha,4alpha,5alpha)-isomer C0894897 59573-80-7 M0047553 M0309292 T339292 beta-thujone, (1alpha,4alpha,5alpha)-isomer 1999 08 18 M0309291 beta-thujone, (1S-(1alpha,4alpha,5alpha))-isomer C0894896 546-80-5 M0047553 M0309291 T339291 beta-thujone, (1S-(1alpha,4alpha,5alpha))-isomer 1999 08 18 M0309290 beta-thujone, 1S-(1alpha,4beta,5alpha)-isomer C0894895 471-15-8 M0047553 M0309290 T339290 beta-thujone, 1S-(1alpha,4beta,5alpha)-isomer 1999 08 18 C003421 tetrin B 1971 01 01 1989 08 08 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN not in Chemline 7/83; RN in 9th CI 0 GLYCOSIDES (74-76) LACTONES (77-89) *D015548 Antibiotics, Macrolide J Antibiot 29(10):1035;1976 NLM RJM RLS M0044467 tetrin B C0076345 34280-27-8 T074470 tetrin B C003422 tetronic acid 1971 01 01 1983 07 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure; in fifth source 11 *D005663 Furans Arch Pharm (Weinheim) 311(12):986;1978 Chem Pharm Bull 1979;27(8):1901 Clin Chem 21(13):1892;1975 J Gen Microbiol 95(2):395;1976 Monosacch Polyalcohols Nutr Ther Diet 15:216;1976 NLM ACS NLM M0044468 tetronic acid C0076353 2,4(3H,5H)-furandione 4971-56-6 T074471 tetronic acid C003424 2-hydroxyaclacinomycin A 1982 02 09 1988 07 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure in first source 4 NAPHTHACENES (82-88) D015250 Aclarubicin *Q000031 analogs ; derivatives J Antibiot (Tokyo) 1981;34(11):1494 NBM RGM NLM M0044471 2-hydroxyaclacinomycin A C0046178 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,9-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O-((2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R-(1alpha,2beta,4beta))- 79127-36-9 T074474 2-hydroxyaclacinomycin A C003431 thermosan 1972 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination drug containing pelargonic vanillylamide, benzyl nicotinate, ethanolamine salicylate 0 *BENZOATES (72-75) *D004983 Ethanolamines *D009539 Nicotinic Acids D004338 Drug Combinations D014641 Vanillic Acid *Q000031 analogs ; derivatives NLM RLS NLM M0044476 thermosan C0601792 Thermosan 79102-55-9 T074479 thermosan C101371 3-thujol 1996 10 21 2001 04 03 1998 1999 2000 2001 2001A 2002 RN given for (1S-(1alpha,3alpha,4alpha,5alpha))-isomer; structure in first source 1 *D001643 Bicyclo Compounds Bioorg Med Chem 1996 Mar;4(3):419-21 THA TWD TWD M0265774 3-thujol C0529687 21653-20-3 3284-85-3 ((1R-(alpha,3alpha,4alpha5alpha))-isomer) M0265774 M0327616 T295779 3-thujol M0327616 3-thujol, (1R-(alpha,3alpha,4alpha5alpha))-isomer C0960090 3284-85-3 M0265774 M0327616 T357616 3-thujol, (1R-(alpha,3alpha,4alpha5alpha))-isomer 1999 08 18 C003440 thioacridone 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 THIONES (74-76) *D000166 Acridines J Pharm Sci 60(8):1238;1971 NLM NLM M0044492 thioacridone C0601798 9(10H)-Acridinethione 6540-78-9 T074495 thioacridone C003442 thioanisidine 1972 01 01 1982 06 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 in Chemline RN above is for para-isomer; structure 0 *SULFIDES (72-76) *D000814 Aniline Compounds Biochem Pharmacol 21(7):1009;1972 NLM ESH NLM M0044495 thioanisidine C0076440 104-96-1 T074498 thioanisidine C003445 thiocytidylate 1972 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CYTOSINE NUCLEOTIDES (72-75) SULFIDES (72-76) *D013873 Thionucleotides D003568 Cytidine Monophosphate *Q000031 analogs ; derivatives Eur J Biochem 27(1):109;1972 NLM RLS NLM M0044500 thiocytidylate C0601802 5'-Cytidylic acid, 2-thio- 36238-43-4 T074503 thiocytidylate C003446 thiohempa 1973 01 01 1995 12 12 1996 1997 1998 1999 2000 2001 2002 0 *ORGANOTHIOPHOSPHORUS COMPOUNDS (73-75) DIMETHYLAMINES (73-75) SULFIDES (75-76) D006492 Hempa *Q000031 analogs ; derivatives FEBS Lett 95(1):107;1978 J Econ Entomol 64:1027 NLM MLH NLM M0044501 thiohempa C0076471 hexamethylphosphorothioic triamide 3732-82-9 T074504 thiohempa C003449 thioinosinic acid 1972 01 01 1993 04 28 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 12 *INOSINE NUCLEOTIDES (72-75) MERCAPTOPURINE (72-75) MERCAPTOPURINE/analogs (75-77) *D013873 Thionucleotides D007291 Inosine Monophosphate *Q000031 analogs ; derivatives Biochemistry 1980;19(1):215 Cancer Res 36(10):3779;1976 Cancer Res 37:3668;1977 Proc Soc Exp Biol Med 140(2):423;1972 NLM BVL NLM M0044506 thioinosinic acid C0076474 53-83-8 15020-63-0 (ion(-2)) M0044506 M0044502 M0044506 M0044505 M0044506 M0308301 M0044506 M0044504 M0044506 M0044503 T074509 thioinosinic acid M0044502 6-TIMP C0167160 M0044506 M0044502 T074505 6-TIMP M0044505 6-thioinosine 5'-monophosphate C0167161 M0044506 M0044505 T074508 6-thioinosine 5'-monophosphate M0308301 ion(-2) of thioinosinic acid C0894439 15020-63-0 M0044506 M0308301 T338301 ion(-2) of thioinosinic acid 1999 08 18 M0044504 6-thio-IMP C0099448 M0044506 M0044504 T074507 6-thio-IMP M0044503 6-mercaptopurine ribonucleoside 5'-monophosphate C0099294 M0044506 M0044503 T074506 6-mercaptopurine ribonucleoside 5'-monophosphate C003450 2-thiolacetoxybenzanilide 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 substrate for tissue esterases; structure 0 SULFIDES (72-76) *D000813 Anilides Ann Otol Rhinol Laryngol 81(3):378;1972 NLM NLM M0044507 2-thiolacetoxybenzanilide C0601803 Ethanethioic acid, O-(2-((phenylamino)carbonyl)phenyl) ester 53372-00-2 T074510 2-thiolacetoxybenzanilide C003452 thiopeptin A 1972 01 01 1993 05 03 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 PEPTIDES (72-93) SULFIDES (72-76) *D017561 Antibiotics, Peptide Antimicrob Agents Chemother 1(3):192;1972 Antimicrob Agents Chemother 1(6):496;1972 NLM PML TPW M0044511 thiopeptin A C0076500 79102-56-0 T074514 thiopeptin A C003453 thiopeptin B 1972 01 01 1993 05 03 1994 1995 1996 1997 1998 1999 2000 2001 2002 4 PEPTIDES (72-93) SULFIDES (72-76) *D017561 Antibiotics, Peptide Antimicrob Agents Chemother 1(6):496;1972 J Antibiot 30(5):383;1977 NLM PML TPW M0044512 thiopeptin B C0076501 37339-66-5 T074515 thiopeptin B C035127 sabinene 1982 08 30 2001 03 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to cpd without isomeric designation 9 *D013729 Terpenes Arch Biochem Biophys 1982;216(2):616 MEG TWD TWD M0107834 sabinene C0073920 3387-41-5 2009-00-9 ((1R)-isomer) M0107834 M0320276 T137838 sabinene M0320276 sabinene, (1R)-isomer C0970430 2009-00-9 M0107834 M0320276 T350276 sabinene, (1R)-isomer 1999 08 18 C003463 thymidinediphosphomycarose 1973 01 01 1985 08 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *NUCLEOSIDE DIPHOSPHATE SUGARS (73-75) *THYMIDINE DIPHOSPHATE SUGARS (75-85) THYMIDINE (73-75) *D009702 Nucleoside Diphosphate Sugars Arch Mikrobiol 88(1):25;1972 NLM LCR NLM M0044518 thymidinediphosphomycarose C0601808 Thymidine 5'-(trihydrogen diphosphate), mono(2,6-dideoxy-3-C-methyl-L-ribo-hexopyranosyl) ester 39950-81-7 T074521 thymidinediphosphomycarose C003465 thymohydroquinone 1971 01 01 1994 09 30 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *HYDROQUINONES (71-75) D013943 Thymol *Q000031 analogs ; derivatives Pharmazie 30(2):109;1975 NLM MLH TPW M0044523 thymohydroquinone C0076604 2217-60-9 T074526 thymohydroquinone C074065 Brain-1 protein, mouse 1992 05 13 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; expressed in adult mouse brain by POU domain gene Brain-1 1 *D004268 DNA-Binding Proteins *D009419 Nerve Tissue Proteins Proc Natl Acad Sci U S A 1992 Apr 15;89(8):3280-4 THA WXM WXM M0200066 Brain-1 protein, mouse C0651075 147258-10-4 T230071 Brain-1 protein, mouse T230070 mouse Brain-1 protein C003489 N-methylpiperidine-4-yl-2-cyclohexyl-2-hydroxy-2- phenylacetate 1972 01 01 1982 09 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 acetylcholine antagonists; structure 1 CYCLOHEXANES (72-76) PIPERIDINES (72-82) *D010648 Phenylacetates J Pharm Pharmacol 23(10):745;1971 NLM VSR NLM M0044543 N-methylpiperidine-4-yl-2-cyclohexyl-2-hydroxy-2- phenylacetate C0601810 33445-17-9 T074546 N-methylpiperidine-4-yl-2-cyclohexyl-2-hydroxy-2- phenylacetate C003493 O-methylpsychotrine oxylate 1972 01 01 1982 09 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 alkaloid found in Ipecac 0 IPECAC (72-76) OXALATES (72-81) *D000470 Alkaloids Mol Pharmacol 7(2):122;1971 NLM VSR NLM M0044550 O-methylpsychotrine oxylate C0601814 14637-07-1 T074553 O-methylpsychotrine oxylate C003494 methyl pyridylcarbonate 1972 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CARBONATES (72-76) *D011725 Pyridines Biochemistry 11(2):159;1972 NLM NLM M0044551 methyl pyridylcarbonate C0601815 0 T074554 methyl pyridylcarbonate C074106 NHP1 protein 1992 05 17 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; isolated from Babesia bovis; MW 11,116 Da 3 *D004268 DNA-Binding Proteins *D006609 High Mobility Group Proteins D016793 Babesia bovis Biochem Biophys Res Commun 1992 Apr 15;184(1):31-5 THA WXM WXM M0200165 NHP1 protein C0167265 147386-98-9 T230170 NHP1 protein T230169 protein NHP1 C003469 ticarbodine 1972 01 01 2001 01 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 *TOLUIDINES (72-82) THIONES (74-76) *D010880 Piperidines Am J Vet Res 33(4):709;1972 Tijdschr Diergeneeskd 100(21):1156;1975 NLM TWD TWD M0044532 ticarbodine C0076661 31932-09-9 T074535 ticarbodine Negwer, 5th ed, #2823 USAN 1978, p.311 T074534 alpha,alpha,alpha-trifluoro-2,6-dimethylthio- 1-piperidinecarboxy-m-toluidide C003549 dacuronium 1971 01 01 2000 07 31 2001 2002 RN given refers to parent cpd without isomeric designation; structure 12 *ANDROSTANEDIOL/analogs (75-77) *ANDROSTANES (71-75) PIPERIDINES (71-76) D010197 Pancuronium *Q000031 analogs ; derivatives Acta Anaesthesiol Scand 21:24;1977 Anaesthesia 31(2):215;1976 Indian J Physiol Pharmacol 21(3):195;1978 NLM CCR sjn M0044587 dacuronium C0057088 2 beta,16 beta-dipiperidino-5 alpha-androstane-17 beta-diol 3 alpha-acetato dimethobromide 43021-45-0 T110 Steroid T121 Pharmacologic Substance 27115-86-2 (dibromide(3alpha)-isomer) 40598-96-7 (dibromide(3beta)-isomer) M0044587 M0044585 M0044587 M0308319 M0044587 M0308320 M0044587 M0044586 M0044587 M0044583 M0044587 M0044584 T074590 dacuronium M0044585 dacuronium bromide C0112241 T110 Steroid T121 Pharmacologic Substance M0044587 M0044585 T074588 dacuronium bromide M0308319 dacuronium dibromide, (3alpha)-isomer C0894456 27115-86-2 T110 Steroid T121 Pharmacologic Substance M0044587 M0308319 T338319 dacuronium dibromide, (3alpha)-isomer 1999 08 18 M0308320 dacuronium dibromide, (3beta)-isomer C0894457 40598-96-7 T110 Steroid T121 Pharmacologic Substance M0044587 M0308320 T338320 dacuronium dibromide, (3beta)-isomer 1999 08 18 M0044586 Gestormone C0119101 T110 Steroid T121 Pharmacologic Substance M0044587 M0044586 T074589 Gestormone M0044583 Mercilon C0127576 T110 Steroid T121 Pharmacologic Substance M0044587 M0044583 T074586 Mercilon M0044584 Organon N.B.68 C0134092 T110 Steroid T121 Pharmacologic Substance M0044587 M0044584 T074587 Organon N.B.68 C003522 17-aminopregn-4-ene-3,20-dione 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 17-amino deriv of progesterone 0 *PROGESTERONE (73-75) AMINES (73-76) D011374 Progesterone *Q000031 analogs ; derivatives NLM VSR NLM M0044566 17-aminopregn-4-ene-3,20-dione C0601820 Pregn-4-ene-3,20-dione, 17-amino- 18211-54-6 T074569 17-aminopregn-4-ene-3,20-dione C003523 androsta-3,5-diene-3,17-diol diacetate 1973 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 enol deriv of testosterone 0 *TESTOSTERONE (73-75) D013739 Testosterone *Q000031 analogs ; derivatives NLM VSR NLM M0044567 androsta-3,5-diene-3,17-diol diacetate C0601821 Androsta-3,5-diene-3,17-diol, diacetate, (17beta)- 1778-93-4 T074570 androsta-3,5-diene-3,17-diol diacetate C074120 trypanosome DNA-binding protein 1 1992 05 19 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; a high mobility group (HMG) 1-like protein from African trypanosomes 1 *D004268 DNA-Binding Proteins *D015800 Protozoan Proteins D016833 Trypanosoma brucei rhodesiense Mol Biochem Parasitol 1992 Mar;51(1):111-8 BXB WXM WXM M0200214 trypanosome DNA-binding protein 1 C0651115 146635-37-2 T230219 trypanosome DNA-binding protein 1 T230218 TDP 1 C003535 campestanol 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 20 *D010840 Phytosterols NLM NLM M0044577 campestanol C0601822 24 alpha-methyl-5 alpha-cholestan-3 beta-ol 474-60-2 T074580 campestanol C003537 6-carboxymethylprogesterone 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PROGESTERONE (73-75) CARBOXYLIC ACIDS (75-76) D011374 Progesterone *Q000031 analogs ; derivatives J Steroid Biochem 3(3):357;1972 NLM NLM M0044578 6-carboxymethylprogesterone C0601823 0 T074581 6-carboxymethylprogesterone C003538 6-carboxymethyltestosterone 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *TESTOSTERONE (73-75) ACETIC ACIDS (73-75) D008777 Methyltestosterone *Q000031 analogs ; derivatives J Steroid Biochem 3(3):357;1972 NLM NLM M0044579 6-carboxymethyltestosterone C0601824 0 T074582 6-carboxymethyltestosterone C006448 aldrin-transdiol 1974 01 01 2000 07 31 2001 2002 dieldrin metabolite suggested as active neurotoxic form; RN refers to (1 alpha,2 alpha,3 beta,4 alpha,4a beta,5 alpha,8 alpha,8a beta)-isomer 1 *ALDRIN (74-75) D000452 Aldrin *Q000031 analogs ; derivatives Arch Int Pharmacodyn Ther 206(2):363;1973 Drug Metab Dispos 2(4):333;1974 Eur J Pharmacol 31(2):166;1975 Eur J Pharmacol 34(1):133;1975 NLM TWD sjn M0049034 aldrin-transdiol C0051139 trans-6,7-dihydroxydihydroaldrin 3106-29-4 T109 Organic Chemical T121 Pharmacologic Substance 30460-74-3 ((1alpha,2alpha,3alpha,4alpha,4abeta,5alpha,8alpha,8abeta)-isomer) M0049034 M0309561 T079037 aldrin-transdiol T079036 dihydroaldrindiol M0309561 aldrin-transdiol, (1alpha,2alpha,3alpha,4alpha,4abeta,5alpha,8alpha,8abeta)-isomer C0895090 30460-74-3 T109 Organic Chemical T121 Pharmacologic Substance M0049034 M0309561 T339561 aldrin-transdiol, (1alpha,2alpha,3alpha,4alpha,4abeta,5alpha,8alpha,8abeta)-isomer 1999 08 18 C035588 fatty acyl amidases 1982 10 04 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amidases I ; II act sequentially on lipopolysaccharides cleaving hydroxymyristyl groups 4 *D000581 Amidohydrolases J Biol Chem 1982;257(17):10222 VSR CCR CCR M0108967 fatty acyl amidases C0060096 EC 3.5.1.- M0108967 M0108965 M0108967 M0108966 T138971 fatty acyl amidases M0108965 fatty acyl amidase I C0117320 M0108967 M0108965 T138969 fatty acyl amidase I M0108966 fatty acyl amidase II C0117321 M0108967 M0108966 T138970 fatty acyl amidase II C003547 16 alpha-cyanoestradiol 3-methyl ether 1973 01 01 1981 08 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ESTRANES (73-75) METHYL ETHERS (73-81) NITRILES (73-76) D004958 Estradiol *Q000031 analogs ; derivatives NLM NBM NLM M0044582 16 alpha-cyanoestradiol 3-methyl ether C0044916 Estra-1,3,5(10)-triene-16-carbonitrile, 17-hydroxy-3-methoxy-, (16alpha,17beta)- 69381-96-0 T074585 16 alpha-cyanoestradiol 3-methyl ether C003687 TFM 1972 01 01 2000 06 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 sea lamprey larvicide 2 *CRESOLS (74-80) FLUORINE (72-74) HYDROCARBONS, FLUORINATED (74-76) NITRO CPDS (74-80) *D009596 Nitrophenols Comp Biochem Physiol 48(3):555;1974 J Agric Food Chem 27(2):328;1979 J Assoc Off Anal Chem 59(4):862;1976 Toxicol Appl Pharmacol 20(2):216;1971 NLM CCR CCR M0044748 TFM C0076363 4-nitro-3- (trifluoromethyl)phenol 88-30-2 T109 Organic Chemical T131 Hazardous or Poisonous Substance T074751 TFM Merck Index, 9th ed, p. 1192, #8966 T074749 3-trifluoromethyl-4-nitrophenol T074750 alpha,alpha,alpha-trifluoro-4-nitro-m-cresol C003591 16 beta-hydroxy-19-nortestosterone 16,17-acetonide 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ESTRANES (74-75) *TESTOSTERONE (73-74) ACETALS (73-75) HYDROXYSTEROIDS (73-76) KETOSTEROIDS (73-75) NORSTEROIDS (73-74) D009277 Nandrolone *Q000031 analogs ; derivatives NLM NLM M0044617 16 beta-hydroxy-19-nortestosterone 16,17-acetonide C0601831 Estr-4-en-3-one, 16,17-((1-methylethylidene)bis(oxy))-, (16beta,17beta)- 78592-87-7 T074620 16 beta-hydroxy-19-nortestosterone 16,17-acetonide C004924 dibutyltin diacetate 1973 01 01 2000 06 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 4 *ORGANOMETALLIC COMPOUNDS (73-75) *TIN (73-75) BUTANES (75-76) *D009947 Organotin Compounds Fd Cosmet Toxicol 11(2):255;1973 Febs Lett 82(1):23;1977 J Invest Dermatol 68:379;1977 NLM CCR CCR M0046140 dibutyltin diacetate C0057810 1067-33-0 T109 Organic Chemical T076143 dibutyltin diacetate C003593 17-hydroxypregnenedione 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 *PREGNENES (73-74) HYDROXYSTEROIDS (74-76) KETOSTEROIDS (73-74) *D011282 Pregnenediones NLM NLM M0044619 17-hydroxypregnenedione C0601832 17 alpha-hydroxypregn-5-ene-3,20-dione 641-80-5 T074622 17-hydroxypregnenedione C003597 1 beta-hydroxytetrahydrocortisone 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PREGNANES (73-75) 17-HYDROXYCORTICOSTEROIDS (73-75) HYDROXYSTEROIDS (73-76) TETRAHYDROCORTISONE (73-75) D013761 Tetrahydrocortisone *Q000031 analogs ; derivatives NLM NLM M0044621 1 beta-hydroxytetrahydrocortisone C0601833 1 beta,3 alpha,17 alpha,21-tetrahydroxy-5 beta- pregnane-11,20-dione 10536-01-3 T074624 1 beta-hydroxytetrahydrocortisone C437483 bis(1,2-benzisothiazol-3(2H)-one 1,1-dioxido-N:O)bis(1,2-benzisothiazol-3(2H)-one 1,1-dioxido-N)bis(imidazole)copper(II) 2001 10 22 2001 10 22 2001 2001A 2002 structure in first source 1 *D009942 Organometallic Compounds *D013844 Thiazoles D003300 Copper Acta Crystallogr C 2001 Sep;57(Pt 9):1016-9 SZM SZM SZM M0402583 bis(1,2-benzisothiazol-3(2H)-one 1,1-dioxido-N:O)bis(1,2-benzisothiazol-3(2H)-one 1,1-dioxido-N)bis(imidazole)copper(II) 0 T109 Organic Chemical T467272 bis(1,2-benzisothiazol-3(2H)-one 1,1-dioxido-N:O)bis(1,2-benzisothiazol-3(2H)-one 1,1-dioxido-N)bis(imidazole)copper(II) 2001 10 22 T467274 B(BIT)-ODK-B(BIT)ODK-B(I)Cu(II) 2001 10 22 T467273 bis(mu-1,2-benzisothiazol-3(2H)-one 1,1-dioxido-kappa(2)N:O)bis(1,2-benzisothiazol-3(2H)-one 1,1-dioxido-kappaN)bis(imidazole)copper(II) 2001 10 22 C003608 tirandamycin A 1972 01 01 1987 08 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 antibiotic related to streptolydigin 3 ANTIBIOTICS (72-87) PYRROLIDINONES (72-87) *D000901 Antibiotics, Aminoglycoside Arch Microbiol 109(1-2):65;1976 NLM DLV NLM M0044631 tirandamycin A C0076722 34429-70-4 T074634 tirandamycin A C437544 lacticin BH5 2001 10 22 2001 2002 1 *D001430 Bacteriocins D013294 Lactococcus lactis J Food Prot 2000 Dec;63(12):1707-12 SXK SXK M0402644 lacticin BH5 0 T123 Biologically Active Substance T467334 lacticin BH5 2001 10 22 C008164 1-ipomeanol 1975 01 01 2001 02 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 lung-toxic furanoterpenoid produced in sweet potatoes infected with Fusarium solani; structure 0 FURANS (75-82) *D013729 Terpenes D014118 Toxins Biochim Biophys Acta 337(1):184;1973 NLM TWD TWD M0051770 1-ipomeanol C0603460 5-(3- furanyl)-5-hydroxy-2-pentanone 34435-70-6 T081773 1-ipomeanol T081772 1-(3-furyl)-1-hydroxy-4-pentanone C003622 Tranquo-Buscopan 1971 01 01 1982 11 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination drug of buscopan ; oxazepam 0 *SCOPOLAMINE (71-80) BROMINE (71-73) *D002086 Butylscopolammonium Bromide *D010076 Oxazepam D004338 Drug Combinations NLM RLS NLM M0044664 Tranquo-Buscopan C0601836 3-Oxa-9-azoniatricyclo(3.3.1.02,4)nonane, 9-butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-, bromide, (7(S)-(1alpha,2beta,4beta,5alpha,7beta))-, mixt. with 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one 78940-00-8 T074667 Tranquo-Buscopan C003635 3,4-10,11-12,13-tribenzofluoranthene 1970 01 01 1983 08 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN ; Nl from 9th CI; cpd not in Chemline 8/4/83 0 BENZENE DERIVATIVES (70-76) *D005449 Fluorenes NLM JSL NLM M0044683 3,4-10,11-12,13-tribenzofluoranthene C0601842 phenanthro(9,10-e)acephenanthrylene 13579-05-0 T074686 3,4-10,11-12,13-tribenzofluoranthene C003638 1,2,3-tricarboxy-1-cyclopentene 1972 01 01 1982 09 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 inhibitor of cis-aconitase 0 CYCLOPENTANES (72-82) *D014233 Tricarboxylic Acids Arch Biochem Biophys 147(2):772;1971 NLM VSR NLM M0044693 1,2,3-tricarboxy-1-cyclopentene C0601843 1-Cyclopentene-1,2,3-tricarboxylic acid 31602-26-3 T074696 1,2,3-tricarboxy-1-cyclopentene C003639 trichloroiodopyridine 1972 01 01 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 CHLORINE (72-74) IODINE (72-74) *D011725 Pyridines Arch Roum Pathol Exp Microbiol 29(3):385;1970 NLM NLM M0044694 trichloroiodopyridine C0601844 Pyridine, trichloroiodo- 26856-63-3 T074697 trichloroiodopyridine C008171 Iskedyl 1975 01 01 2001 02 02 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 combination of raubasine ; dihydroergotoxine used therapeutically in otoneurologic ischemias 1 *ERGOLOID MESYLATES (75-76) *D004088 Dihydroergotoxine *D015016 Yohimbine D004338 Drug Combinations Ann Anesthesiol Fr 16(2):69;1975 J Fr Otorhinolaryngol 23(7):649;1974 NLM TWD TWD M0051792 Iskedyl C0063898 Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, (19alpha)-, mixt. with (5'alpha,10alpha)-9,10-dihydro-12'-hydroxy-2'-(1-methylethyl)-5'-(phenylmethyl)ergotaman-3',6',18-trione 96743-85-0 M0051792 M0051791 T081795 Iskedyl M0051791 PF 50 C0136192 M0051792 M0051791 T081794 PF 50 C437546 N-4-chlorobenzoyl-N'-benzoyl-N'-tert-butylhydrazine 2001 10 22 2001 2002 structure in first source 2 *D006834 Hydrazines *D020185 Benzoic Acids J Agric Food Chem 2001 Jun;49(6):2894-8 SXK SXK M0402646 N-4-chlorobenzoyl-N'-benzoyl-N'-tert-butylhydrazine 0 T109 Organic Chemical T467338 N-4-chlorobenzoyl-N'-benzoyl-N'-tert-butylhydrazine 2001 10 22 T467339 halofenozide 2001 10 22 C437547 capsular polysaccharide K24 2001 10 22 2001 2002 1 *D011135 Polysaccharides, Bacterial D007711 Klebsiella pneumoniae Biol Signals Recept 2001 Sep-Oct;10(5):294-8 SXK SXK M0402648 capsular polysaccharide K24 0 T118 Carbohydrate T467341 capsular polysaccharide K24 2001 10 22 T467342 K24-CPS 2001 10 22 C003654 7-methoxydehydroepiandrosterone 1973 01 01 1992 06 18 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *DEHYDROEPIANDROSTERONE (73-75) METHYL ETHERS (73-76) D003687 Prasterone *Q000031 analogs ; derivatives NLM MLH TPW M0044717 7-methoxydehydroepiandrosterone C0601853 0 T074720 7-methoxydehydroepiandrosterone C005000 flavaspidic acid 1969 01 01 2000 06 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 isolated from rhizomes of male fern; structure 4 CYCLOHEXANOLS (73-76) *D002090 Butyrophenones Biochem Pharmacol 27:897;1978 Biochim Biophys Acta 1980;617(1):156 NLM CCR CCR M0046264 flavaspidic acid C0060427 3'-((5-butyryl-2,4-dihydroxy-3,3-dimethyl-6-oxo-1,4-cyclohexadien-1-yl)methyl)-5'-methylphloro butyrophenone 114-42-1 T109 Organic Chemical T076267 flavaspidic acid Merck Index, 9th ed, p. 531, #4004 C045648 odorant-binding protein 1985 07 16 2001 10 22 1999 2000 2000A 2001 2001A 2001B 2002 binds 'green' smelling odorants such as 2-isobutyl-3-methoxypyrazine; has been sequenced; GenBank AJ251020-9 (human) 103 *CARRIER PROTEINS (85-93) *D018035 Receptors, Odorant D009812 Odors D009831 Olfactory Mucosa D011719 Pyrazines D018034 Olfactory Receptor Neurons Eur J Biochem 1985;149(2):227 MEG SXK SXK M0132648 odorant-binding protein C0069375 0 M0132648 M0132641 M0132648 M0132645 M0132648 M0132642 M0132648 M0132643 M0132648 M0132644 M0132648 M0132647 M0132648 M0402649 T162653 odorant-binding protein T162651 odor-binding protein M0132641 2-isobutyl-3-methoxypyrazine-binding protein C0093203 M0132648 M0132641 T162646 2-isobutyl-3-methoxypyrazine-binding protein M0132645 general odorant-binding protein, GOBP2 C0752998 M0132648 M0132645 T162650 general odorant-binding protein, GOBP2 M0132642 LUSH protein C0752997 M0132648 M0132642 T162647 LUSH protein M0132643 OBP-II C0624480 M0132648 M0132643 T162648 OBP-II M0132644 OBP-III C0624481 M0132648 M0132644 T162649 OBP-III M0132647 pyrazine-binding protein C0139428 M0132648 M0132647 T162652 pyrazine-binding protein M0402649 OBP-3 protein M0132648 M0402649 T467343 OBP-3 protein 2001 10 22 C003669 pregn-5-ene-3,20-dione 1974 01 01 1982 07 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 *PREGNENEDIONES (75-78) *PROGESTERONE (74-75) *D011374 Progesterone D007536 Isomerism J Reprod Fertil 36(1):83;1974 NLM ESH NLM M0044729 pregn-5-ene-3,20-dione C0071847 1236-09-5 T074732 pregn-5-ene-3,20-dione C008180 isoferulic acid 1974 01 01 2001 02 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 isomer of ferulic acid; structure 12 METHYL ETHERS (74-79) *D002934 Cinnamates Acta Pol Pharm 30(4):353;1973 NLM TWD TWD M0051805 isoferulic acid C0162986 3-(3-hydroxy-4-methoxyphenyl)-2-propenoic acid 537-73-5 T081808 isoferulic acid T081807 3-hydroxy-4-methoxycinnamic acid C031632 ependymins 1981 09 30 2001 01 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 goldfish brain proteins involved in behavioral plasticity 43 *D009419 Nerve Tissue Proteins J Neurochem 1981;36(4):1368 MEG CCR CCR M0099227 ependymins C0059418 0 T116 Amino Acid, Peptide, or Protein T124 Neuroreactive Substance or Biogenic Amine M0099227 M0099225 M0099227 M0099226 T129231 ependymins M0099225 ependymin beta C0116305 T116 Amino Acid, Peptide, or Protein T124 Neuroreactive Substance or Biogenic Amine M0099227 M0099225 T129229 ependymin beta M0099226 ependymin gamma C0116306 T116 Amino Acid, Peptide, or Protein T124 Neuroreactive Substance or Biogenic Amine M0099227 M0099226 T129230 ependymin gamma C081255 IKe gene 3 protein 1993 06 16 2001 02 02 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 has been sequenced 2 *D014764 Viral Proteins D003090 Coliphages J Virol 1993 Jun;67(6):3332-7 THA WXM WXM M0216768 IKe gene 3 protein C0527627 0 T246773 IKe gene 3 protein T246772 bacteriophage IKe gene 3 protein C045140 visinin 1985 05 31 2001 01 08 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 MW 24,000 protein; found in chick retina ; rat brain 30 *D009419 Nerve Tissue Proteins D005136 Eye Proteins Neuroscience 1985;14(2):547 MEG CCR CCR M0131417 visinin C0078351 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T161422 visinin C005006 glycarbylamide 1969 01 01 2000 06 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 2 DICARBOXYLIC ACIDS (73-76) *D007093 Imidazoles Parazitologiia 12(4):366;1978 Parazitologiia 9(1):82;1975 NLM CCR CCR M0046273 glycarbylamide C0061535 imidazole-4,5-dicarboxamide 83-39-6 T109 Organic Chemical T121 Pharmacologic Substance T076276 glycarbylamide Merck Index, 9th ed, p. 580, #4314 Negwer #223 T076275 glycamide C003691 triglucosylcysteine 1972 01 01 1980 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CYSTEINE (72-74) *GLUCOSE (72-74) *PEPTIDES (72-74) *POLYSACCHARIDES (72-74) GLUCOSE/*analogs (75-80) GLYCOPEPTIDES (72-74) *D005960 Glucosides D003545 Cysteine *Q000031 analogs ; derivatives Nature (New Biol) 234(44):25;1971 NLM NLM M0044752 triglucosylcysteine C0601870 0 T074755 triglucosylcysteine C003694 4,6,8-trihydroxyquinaldic acid 1972 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 metabolite of 3,5-dihydroxy-L-kynurenine 0 *QUINOLINES (72-75) D007736 Kynurenic Acid *Q000031 analogs ; derivatives Wakayama Med Rep 14(4):139;1971 NLM NLM M0044761 4,6,8-trihydroxyquinaldic acid C0601871 0 T074764 4,6,8-trihydroxyquinaldic acid C003696 trilead tetroxide formalin 1972 01 01 1997 05 28 1997 1998 1999 2000 2001 2002 0 *FORMALDEHYDE (72-75) OXIDES (72-76) *D009942 Organometallic Compounds D005557 Formaldehyde *Q000031 analogs ; derivatives D007854 Lead J Tokyo Dent Coll Soc 71(10):2096;1971 NLM TBT NLM M0044762 trilead tetroxide formalin C0601872 (carbonato(2-))dioxotrilead 12287-01-3 T074765 trilead tetroxide formalin C046788 cerebellin 1985 11 15 2001 01 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 cerebellum-specific hexadecapeptide marker for Purkinje cells 18 *D009419 Nerve Tissue Proteins D002531 Cerebellum Proc Natl Acad Sci USA 1985;82(20):7145 MEG CCR CCR M0135420 cerebellin C0055104 94071-26-8 T116 Amino Acid, Peptide, or Protein T124 Neuroreactive Substance or Biogenic Amine T165425 cerebellin T165424 NH2-Ser-Gly-Ser-Ala-Lys-Val-Ala-Phe-Ser-Ala-Ile-Arg-Ser-Thr-Asn-His-OH C005008 tolcyclamide 1973 01 01 2000 06 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 1 CYCLOHEXANES (73-76) TOSYL CPDS (73-75) *D013453 Sulfonylurea Compounds Farm Zh 2:80;1977 NLM CCR CCR M0046279 tolcyclamide C0076794 664-95-9 T109 Organic Chemical T121 Pharmacologic Substance T076282 tolcyclamide Merck, 9th ed, #9210 Negwer, 5th ed, #2590 USAN 1978, p.147 T076279 1-cyclohexyl-3-(p- toluenesulfonyl)urea T076280 cyclamide T076281 glycyclamide C437563 3-hydroxy-1-(2-hydroxy-3,4-dimethoxyphenyl)-2-methylpropanone 2001 10 23 2001 2002 structure in first source 1 D006910 Hydroxypropiophenone *Q000031 analogs ; derivatives Bioorg Med Chem 2001 Oct;9(10):2643-52 BMB BMB M0402664 3-hydroxy-1-(2-hydroxy-3,4-dimethoxyphenyl)-2-methylpropanone 0 T109 Organic Chemical T467353 3-hydroxy-1-(2-hydroxy-3,4-dimethoxyphenyl)-2-methylpropanone 2001 10 23 T467354 3-HHDM cpd 2001 10 23 C003708 trimethyl-3,4-dihydropyrimidine-2-thiol 1971 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 inhibitor of dopamine beta-hydroxylase 0 SULFHYDRYL CPDS (71-76) *D011743 Pyrimidines NLM NLM M0044780 trimethyl-3,4-dihydropyrimidine-2-thiol C0077169 3,4-dihydro-4,4,6-trimethyl-2(1H)-pyrimidinethione 5392-23-4 T074783 trimethyl-3,4-dihydropyrimidine-2-thiol C003711 N(epsilon)-trimethyl-L-delta-hydroxylysine phosphate 1970 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *AMINO ACIDS (70-74) *HYDROXYLYSINE (74-75) AMMONIUM CPDS (74-76) PHOSPHORIC ACIDS (70-74) D006901 Hydroxylysine *Q000031 analogs ; derivatives NLM NLM M0044784 N(epsilon)-trimethyl-L-delta-hydroxylysine phosphate C0601879 0 T074787 N(epsilon)-trimethyl-L-delta-hydroxylysine phosphate C003800 PH.3 1972 01 01 2000 11 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 contains licorice extract, bismuth subnitrate, aminoacetic acid, frangula extract 0 PLANT EXTRACTS (72-82) *D001729 Bismuth *D005998 Glycine D004338 Drug Combinations NLM CCR CCR M0044914 PH.3 C0601906 PH 3 37341-77-8 T104 Chemical Viewed Structurally T121 Pharmacologic Substance T074917 PH.3 C003817 T-1266 1972 01 01 2001 01 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 contains disodium 4-(N-chlorosulfamoyl)benzoate, hexestrol, sodium dodecyl sulfate ; lactose 0 *D006589 Hexestrol *D007785 Lactose *D012967 Sodium Dodecyl Sulfate *D013449 Sulfonamides D004338 Drug Combinations Med Monatschr 26(2):81;1972 NLM TWD TWD M0044930 T-1266 C0601917 D-Glucose, 4-O-beta-D-galactopyranosyl-, mixt. with 4-((chloroamino)sulfonyl)benzoic acid disodium salt, (R*,S*)-4,4'-(1,2-diethyl-1,2-ethanediyl)bis(phenol) and sodium monodecyl sulfate 79102-60-6 T074933 T-1266 T074932 T 1266 C003730 tropone 1972 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 4 *CYCLOHEPTANES (72-75) KETONES (72-74) D014334 Tropolone *Q000031 analogs ; derivatives NLM RLS NLM M0044830 tropone C0077399 2,4,6-cycloheptatrien-1-one 539-80-0 T074833 tropone C003740 ubichromenol 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 3 *BENZOPYRANS (73-75) ALCOHOLS (73-75) *D002839 Chromans Biochem Med 7(1):169;1972 Biokhimiia 43(2):221;1978 Ukr Biohim Zh 47(4):518;1975 Ukr Biokhim Zh 48(2):206;1976 NLM NLM M0044832 ubichromenol C0077654 (R-(all-E))-7,8-dimethoxy-2,5-dimethyl-2-(4,8,12,16,20,24,28,32,36-nonamethyl-3,7,11,15,19,23,27,31,35-heptatriacontanonaenyl)-2H-1-benzo pyran-6-ol 2382-48-1 T074835 ubichromenol C042312 Young's cardioplegic solution 1984 08 23 2000 12 06 1997 1998 1999 2000 2001 2001A 2002 contains 0.8% potassium citrate, 2.46% magnesium sulfate ; neostigmine 8 *CITRATES (84-96) *MAGNESIUM SULFATE (84-96) *NEOSTIGMINE (84-96) *POTASSIUM COMPOUNDS (94-96) POTASSIUM (84-93) D008278 Magnesium Sulfate D009388 Neostigmine D019357 Potassium Citrate D002314 Cardioplegic Solutions Jpn Heart J 1984;25(2):207 RLS CCR CCR M0125021 Young's cardioplegic solution C0078724 0 T109 Organic Chemical T121 Pharmacologic Substance T155026 Young's cardioplegic solution T155025 Young's solution C112689 TAC 101 1998 06 25 2000 12 06 1998 1999 2000 2000A 2001 2001A 2001B 2002 inhibits liver metastasis; structure in first source 12 *D001565 Benzoates *D014297 Trimethylsilyl Compounds Biol Pharm Bull 1996 Oct;19(10):1322-8 THA TWD TWD M0291325 TAC 101 C0675838 0 T109 Organic Chemical T121 Pharmacologic Substance M0291325 M0291320 M0291325 M0291321 T321330 TAC 101 T321329 TAC-101 M0291320 4-(3,5-bis(trimethylsilyl)benzamido)benzoic acid C0675833 T109 Organic Chemical T121 Pharmacologic Substance M0291325 M0291320 T321325 4-(3,5-bis(trimethylsilyl)benzamido)benzoic acid M0291321 Am 555S C0675836 T109 Organic Chemical T121 Pharmacologic Substance M0291325 M0291321 T321326 Am 555S T321327 Am-555S T321328 Am555S C003750 vallarose 1972 01 01 1983 08 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN is from 9th CI; cpd not found in Chemline 8/83 0 *GLYCOSIDES (72-74) DEOXY SUGARS (74-76) HEXOSES (72-82) *D008759 Methylglycosides J Chem Soc 22(0):3762;1971 NLM ACS NLM M0044850 vallarose C0601891 6-deoxy-3-O-methylaltrose 25374-97-4 T074853 vallarose C003755 Vascularin-Gel 1971 01 01 1994 07 28 1995 1996 1997 1998 1999 2000 2001 2002 contains vaculat, sodium heparin ; tincture Arnicae 0 *BAMETHAN (71-94) *D004983 Ethanolamines *D006493 Heparin *D010627 Phenethylamines *D010936 Plant Extracts D004338 Drug Combinations NLM MLH TPW M0044856 Vascularin-Gel C0601894 Heparin, sodium salt, mixt. with alpha-((butylamino)methyl)-4-hydroxybenzenemethanol and Arnica ext. 78920-39-5 T074859 Vascularin-Gel C074160 BlaA protein 1992 05 21 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; an activator-regulator protein from Streptomyces cacaoi 3 *D004268 DNA-Binding Proteins D001426 Bacterial Proteins J Bacteriol 1992 May;174(9):2834-42 BXB WXM WXM M0200307 BlaA protein C0651152 142615-56-3 T230312 BlaA protein T230311 blaA gene product C003763 vinyl bromide 1970 01 01 1980 04 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 18 *HYDROCARBONS, BROMINATED (74-76) *HYDROCARBONS, HALOGENATED (70-74) BROMINE (70-74) *D014753 Vinyl Compounds Arch Toxicol 1979;43(1):83 Biochem Biophys Res Commun 67(2):596;1975 Environ Health Perspect 21:131;1977 Environ Health Perspect 21:17;1977 Vet Hum Toxicol 1980;22(1):31 NLM MEG NLM M0044868 vinyl bromide C0078261 bromoethene 593-60-2 T074871 vinyl bromide C003766 Vitaral 1972 01 01 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 drug composed of many trace metal cpds 0 *D014131 Trace Elements D004338 Drug Combinations Int Arch Arbeitsmed 29(1):64;1971 NLM NLM M0044870 Vitaral C0601896 52504-32-2 T074873 Vitaral C003768 wobe 1972 01 01 1980 09 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *D010447 Peptide Hydrolases Wien Tieraerztl Monatsschr 58(5):193;1971 NLM RLS NLM M0044871 wobe C0601897 EC 3.4.- T074874 wobe C003771 Amberlite XAD-2 resin 1973 01 01 1997 10 11 1997 1998 1999 2000 2001 2002 styrene-divinylbenzene copolymer 130 *RESINS (73-76) *D011137 Polystyrenes D007475 Ion Exchange Resins D012117 Resins, Synthetic AM Ind Hyg Assn J 39(8):678;1978 Anal Biochem 92(2):447;1979 Biochem Med 7(1):145;1973 Bull Environ Contam Toxicol 1979;22(4-5):561 J Anal Chem 48(13):1854;1976 J Anal Chem 50(3):491;1978 J Assoc Off Anal Chem 62(2):241;1979 J Chromatogr 133(1):214;1977 J Chromatogr 145(3):478;1978 J Forensic Sci 20(4):726;1975 Trans Am Soc Artif Intern Organs 1979;25:480 Vet Hum Toxicol 1979;21(Suppl):185 Vet Hum Toxicol 1979;21(Suppl):193 Vutr Boles 76(2):95;1977 Yonago Acta Med 21(2):76;1977 NLM THA NLM M0044887 Amberlite XAD-2 resin C0051551 9060-05-3 M0044887 M0044880 M0044887 M0044883 M0044887 M0044881 M0044887 M0044885 M0044887 M0044884 M0044887 M0044886 M0044887 M0044882 T074890 Amberlite XAD-2 resin M0044880 AR-1 C0103931 M0044887 M0044880 T074883 AR-1 M0044883 Persorb C0136162 M0044887 M0044883 T074886 Persorb M0044881 Biobeads C0106352 M0044887 M0044881 T074884 Biobeads M0044885 copoly(styrene-divinylbenzene) C0110655 M0044887 M0044885 T074888 copoly(styrene-divinylbenzene) M0044884 XAD-2 resin C0148938 M0044887 M0044884 T074887 XAD-2 resin M0044886 poly(styrene-divinylbenzene) C0137656 M0044887 M0044886 T074889 poly(styrene-divinylbenzene) M0044882 Empore C0601898 M0044887 M0044882 T074885 Empore C003778 yemenimycin 1972 01 01 1993 05 03 1994 1995 1996 1997 1998 1999 2000 2001 2002 isolated from Streptomyces AS-Y-52 0 PEPTIDES (72-93) *D017561 Antibiotics, Peptide Cancer Treat Rep 60(7):937;1976 J Antibiot (Tokyo) 24(9):593;1971 NLM PML TPW M0044894 yemenimycin C0078692 12764-56-6 T074897 yemenimycin C074192 trpl protein 1992 05 25 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; contains 2 possible calmodulin-binding sites; structurally resembles cation channel proteins; isolated from Drosophila heads 52 *D002148 Calmodulin-Binding Proteins *D008565 Membrane Proteins D004330 Drosophila D007473 Ion Channels Neuron 1992 Apr;8(4):631-42 THA WXM WXM M0200392 trpl protein C0167455 146589-79-9 T230397 trpl protein T230396 transient receptor potential-like protein C003787 zorbamycin 1972 01 01 1987 03 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 antibiotic related to bleomycin ; phleomycin 1 PEPTIDES (72-76) D009942 Organometallic Compounds D003300 Copper J Antibiot (Tokyo) 24(8):543;1971 NLM PEH NLM M0044906 zorbamycin C0078848 11056-20-5 T074909 zorbamycin C112667 NC 67722 1998 06 25 2000 12 06 1999 2000 2001 2001A 2002 iodinated nanoparticle suspension used for imaging regional lymph node metastases; structure in second source 3 *CONTRAST MEDIA (98-99) *D001565 Benzoates Acad Radiol 1998 Apr;5 Suppl 1:S180-S182 Acad Radiol 1999 Jan;6(1):55-60 THA TWD TWD M0291278 NC 67722 C0675793 0 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0291278 M0291276 T321283 NC 67722 T321282 NC-67722 M0291276 6-(ethoxycarbonyl)hexyl-bis(3,5-acetylamino-2,4,6-triiodobenzoate) C0754821 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0291278 M0291276 T321281 6-(ethoxycarbonyl)hexyl-bis(3,5-acetylamino-2,4,6-triiodobenzoate) C003807 Dona 200 1971 01 01 1980 01 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination drug containing lidocaine ; D-glucosamine salts in water 1 *D005944 Glucosamine *D008012 Lidocaine D004338 Drug Combinations Arch Int Pharmacodyn Ther 192(2):279;1971 NLM PLS NLM M0044920 Dona 200 C0058681 2-amino-2-deoxy-D-glucose hydriodide, mixt. with 2-amino-2-deoxy-D-glucose hydrochloride, 2-amino-2-deoxy-D-glucose sulfate (salt) ; 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide monohydrochloride 8075-86-3 T074923 Dona 200 Negwer, 4th ed, #434c (without lidocaine) C003809 CR 242 B 1972 01 01 1981 07 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination drug containing buscapine ; proglumide; used as therapeutic agent in gastrointestinal diseases, ulcers 0 *GLUTARATES (72-75) *SCOPOLAMINE (72-80) *D002086 Butylscopolammonium Bromide *D011377 Proglumide D004338 Drug Combinations Rev Esp Enferm Apar Dig 36(2):231;1972 NLM NBM NLM M0044923 CR 242 B C0601912 3-Oxa-9-azoniatricyclo(3.3.1.0(2,4))nonane, 9-butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-, bromide, (7(S)-(1alpha,2beta,4beta,5alpha,7beta))-, mixt. with (+-)-4-(benzoylamino)-5-(dipropylamino)-5-oxopentanoic acid 76207-50-6 T074926 CR 242 B C003810 R. 306 1971 01 01 1988 07 25 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains homatropine ethobromide, aminoxyscopolamine.HBr ; pyridoxine.HCl 0 *BELLADONNA ALKALOIDS (71-88) *SCOPOLAMINE (74-75) *D011736 Pyridoxine *D012602 Scopolamine Derivatives *D014326 Tropanes D004338 Drug Combinations NLM TPW NLM M0044924 R. 306 C0601913 0 T074927 R. 306 C003849 3,3',5-triiodothyroacetic acid N,N-diethanolamine (1:1) complex 1973 01 01 1982 02 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 thyromimetic agent; structure 0 *TRIIODOTHYRONINE (73-75) ACETIC ACIDS (73-76) D014284 Triiodothyronine *Q000031 analogs ; derivatives Biochem Biophys Res Commun 52(2):430;1973 Lancet 2(8031):221;1977 NLM MGR NLM M0044958 3,3',5-triiodothyroacetic acid N,N-diethanolamine (1:1) complex C0046883 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodobenzeneacetic acid, compd. with 2,2'-iminobis(ethanol) (1:1) 1052-92-2 T074961 3,3',5-triiodothyroacetic acid N,N-diethanolamine (1:1) complex C003850 benzyl-2-hydroxyethyl-trisulfide 1973 01 01 1997 07 11 1998 1999 2000 2001 2002 structure 0 *BENZYL COMPOUNDS (73-76) ALCOHOL, ETHYL (73-75) *D013440 Sulfides D000431 Ethanol *Q000031 analogs ; derivatives Arzneim Forsch 22(11):1975;1972 NLM ADP BVL M0044959 benzyl-2-hydroxyethyl-trisulfide C0601929 40096-00-2 T074962 benzyl-2-hydroxyethyl-trisulfide C003856 lachnanthocarpone 1973 01 01 1982 09 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D009281 Naphthalenes D010860 Pigments Biochim Biophys Acta 286(1):88;1972 NLM VSR NLM M0044968 lachnanthocarpone C0601930 2,6-dihydroxy-9-phenyl-1H-phenalen-1-one 28241-21-6 T074971 lachnanthocarpone C003858 2,2,6,6-tetramethyl-4-chloromercuricarbobenzoxypiperidine-1-oxyl 1973 01 01 1982 09 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ORGANOMETALLIC COMPOUNDS (73-76) PIPERIDINES (73-81) *D003497 Cyclic N-Oxides D013113 Spin Labels Mol Biol 6(4):455;1973 NLM VSR NLM M0044969 2,2,6,6-tetramethyl-4-chloromercuricarbobenzoxypiperidine-1-oxyl C0601931 1-Pyrrolidinyloxy, 4-((4-(chloromercurio)phenoxy)carbonyl)-2,2,6,6-tetramethyl- 78717-58-5 T074972 2,2,6,6-tetramethyl-4-chloromercuricarbobenzoxypiperidine-1-oxyl C003859 methylthioethanol 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *MERCAPTOETHANOL (73-75) D008623 Mercaptoethanol *Q000031 analogs ; derivatives Biochim Biophys Acta 286(1):84;1972 NLM NLM M0044970 methylthioethanol C0601932 Ethanol, 2-(methylthio)- 5271-38-5 T074973 methylthioethanol C003862 homoadenosine 6'-phosphonic acid 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 PHOSPHONIC ACIDS (73-76) *D000227 Adenine Nucleotides Biochemistry 12(9):1730;1973 NLM NLM M0044973 homoadenosine 6'-phosphonic acid C0601935 9H-Purin-6-amine, 9-(5-deoxy-6-C-phosphono-beta-D-ribo-hexofuranosyl)- 42155-80-6 T074976 homoadenosine 6'-phosphonic acid C003864 4-methylumbelliferyl phosphorothioate 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *COUMARINS (73-75) ORGANOTHIOPHOSPHORUS COMPOUNDS (73-82) D006923 Hymecromone *Q000031 analogs ; derivatives Nature 241(108):110;1973 NLM RLS NLM M0044974 4-methylumbelliferyl phosphorothioate C0601936 0 T074977 4-methylumbelliferyl phosphorothioate C003938 aclantate 1973 01 01 2001 01 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 ANILINE COMPOUNDS (73-75) TOLUIDINES (73-82) *D013876 Thiophenes Arzneim Forsch 22(12):2146;1972 NLM TWD TWD M0045068 aclantate C0601965 4-(2-chloro-3-methylphenylamino)-3-thiophene carboxylate 16563-09-0 M0045068 M0045067 T075071 aclantate M0045067 HOE 473 C0601964 M0045068 M0045067 T075070 HOE 473 C003903 Nebacetin 1973 01 01 2000 09 27 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 contains bacitracin and neomycin 34 ANTIBIOTICS, COMBINED (89-93) DRUG COMBINATIONS (73-88) D001414 Bacitracin D009355 Neomycin Med Klin 68(17):550;1973 NLM CCR CCR M0045021 Nebacetin C0068474 8025-63-6 T109 Organic Chemical T195 Antibiotic D000894 Anti-Inflammatory Agents, Non-Steroidal D000896 Anti-Inflammatory Agents, Topical D015261 Antibiotics, Combined 53765-20-1 (neomycin sulfate) M0045021 M0308440 T075024 Nebacetin T075023 Nebacitin M0308440 Nebacetin (neomycin sulfate) C0951212 53765-20-1 T109 Organic Chemical T195 Antibiotic M0045021 M0308440 T338440 Nebacetin (neomycin sulfate) 1999 08 18 C003871 25-hydroxyisotachysterol 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 SECOSTEROIDS (73-82) *D013261 Sterols Science 180(089):964;1973 NLM VSR NLM M0044987 25-hydroxyisotachysterol C0601937 0 T074990 25-hydroxyisotachysterol C003876 6,7-dihydroxytetrahydroisoquinoline 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 4 *D007546 Isoquinolines Brain Res 51(0):161;1973 J Chromatogr 114(2):476;1975 NLM NLM M0044990 6,7-dihydroxytetrahydroisoquinoline C0049434 40704-74-3 T074993 6,7-dihydroxytetrahydroisoquinoline C003879 4-pentynoic acid 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 ALKYNES (73-75) PENTANOIC ACIDS (75-76) *D005231 Fatty Acids, Unsaturated Experientia 29(3):277;1973 NLM NLM M0044991 4-pentynoic acid C0601940 6089-09-4 T074994 4-pentynoic acid C003881 cannabivarichromene 1973 01 01 1982 09 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 cannabinoid with a propyl side chain 0 *CANNABIS (73-79) *D002186 Cannabinoids Experentia 29(3):260;1973 NLM VSR NLM M0044992 cannabivarichromene C0601941 41408-19-9 T074995 cannabivarichromene C013841 benzotripte 1977 01 01 2000 09 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 anti-gastrinic; active group is amide; structure 30 *BENZAMIDES (77-81) *D001549 Benzamides Scand J Gastroenterol 11 Suppl 42:113;1976 NLM CCR CCR M0061939 benzotripte C0053254 L-Tryptophan, N-(4-chlorobenzoyl)- 39544-74-6 T109 Organic Chemical T121 Pharmacologic Substance D000897 Anti-Ulcer Agents T091942 benzotripte T091941 benzotript T091940 N-(4-chlorobenzoyl)-L-tryptophan C003886 dihydroxythiobinupharidine 1973 01 01 1981 06 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *QUINOLIZINES (73-81) *D000470 Alkaloids J Pharm Sci 62(5):826;1973 NLM NBM NLM M0044997 dihydroxythiobinupharidine C0601943 30343-70-5 T075000 dihydroxythiobinupharidine C074213 SEC62 protein 1992 05 26 2001 01 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 required for protein translocation across the endoplasmic reticulum; has been sequenced; MW 32 kDa 14 *D005656 Fungal Proteins *D008565 Membrane Proteins D012441 Saccharomyces cerevisiae Cell 1992 Apr 17;69(2):343-52 BXB WXM WXM M0200452 SEC62 protein C0167495 0 T230457 SEC62 protein T230456 SEC62 gene product C003895 10-(2',6'-dimethylphenyl)-3-methylisoalloxazine-6,8- disulfonate 1973 01 01 1982 09 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ARYL SULFONATES (73-82) SULFONIC ACIDS (73-75) *D005415 Flavins Biochemistry 12(11):2083;1973 NLM VSR NLM M0045005 10-(2',6'-dimethylphenyl)-3-methylisoalloxazine-6,8- disulfonate C0601946 Benzo(g)pteridine-6,8-disulfonic acid, 10-(2,6-dimethylphenyl)-2,3,4,10-tetrahydro-3-methyl-2,4-dioxo- 40155-15-5 T075008 10-(2',6'-dimethylphenyl)-3-methylisoalloxazine-6,8- disulfonate C074267 Sm20 protein 1992 05 28 2001 01 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence known 2 *D002135 Calcium-Binding Proteins *D015801 Helminth Proteins D012550 Schistosoma mansoni Parasite Immunol 1991 Nov;13(6):593-604 THA WXM WXM M0200572 Sm20 protein C0167600 0 T230577 Sm20 protein T230576 calcium-binding protein Sm20 C003897 3-O-succinyl digoxigenin iodotyrosine 1973 01 01 1977 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *CARDANOLIDES (73-77) *IODOTYROSINE (73-75) SUCCINATES (73-76) D004076 Digoxigenin *Q000031 analogs ; derivatives D007470 Monoiodotyrosine *Q000031 analogs ; derivatives Clin Chem 19(6):688;1973 NLM NLM M0045008 3-O-succinyl digoxigenin iodotyrosine C0601949 0 T075011 3-O-succinyl digoxigenin iodotyrosine C074300 leukocidin F-component protein 1992 05 31 2001 01 30 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; isolated from Staphococcus aureus; lukF and lukS are apparently cotranscriptionally expressed 13 *D007956 Leukocidins D013211 Staphylococcus aureus Biochem Biophys Res Commun 1992 Apr 30;184(2):640-6 THA WXM WXM M0200665 leukocidin F-component protein C0167654 147096-70-6 T230670 leukocidin F-component protein T230669 LukF protein component C049646 N,N-dimethylformamidase 1986 09 24 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 hydrolyzes N,N-dimethylformamide into dimethylamine ; formate; enzyme isolated from Pseudomonas DMF 3/3 2 *D000581 Amidohydrolases Eur J Biochem 1986;158(3):469 THA CCR CCR M0142145 N,N-dimethylformamidase C0628184 EC 3.5.1.- T172150 N,N-dimethylformamidase T172148 DMFase T172149 N,N-dimethylformamide-hydrolyzing enzyme C003909 5-methylaminomethyl-2-thiouridylate 1973 01 01 1977 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 METHYLAMINES (73-75) THIOURACIL (73-77) *D013873 Thionucleotides *D014500 Uracil Nucleotides Biochem Biophys Res Commun 51(4):1062;1973 NLM NLM M0045030 5-methylaminomethyl-2-thiouridylate C0601954 0 T075033 5-methylaminomethyl-2-thiouridylate C083877 BW 373U86 1993 11 26 2000 09 28 1995 1996 1997 1998 1999 2000 2000A 2001 2002 a nonpeptidic delta opioid receptor agonist 43 *D001549 Benzamides *D010879 Piperazines Mol Pharmacol 1993 Oct;44(4):827-34 BMB CCR CCR M0223039 BW 373U86 C0248151 Benzamide, 4-((2,5-dimethyl-4-(2-propenyl)-1-piperazinyl)(3-hydroxyphenyl)methyl)-N,N-diethyl-, (1(S*),2alpha,5beta)-(+-)- 150428-54-9 T109 Organic Chemical T121 Pharmacologic Substance M0223039 M0223036 T253044 BW 373U86 T253042 BW-373U86 T253043 BW373U86 M0223036 (+-)-4-((alpha-R*)-alpha-((2S*,5R*)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N,N-diethylbenzamide C0248150 T109 Organic Chemical T121 Pharmacologic Substance M0223039 M0223036 T253041 (+-)-4-((alpha-R*)-alpha-((2S*,5R*)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N,N-diethylbenzamide C003920 ethyl red 1973 01 01 1998 01 05 1998 1999 2000 2001 2002 pH indicator dye 0 *D011806 Quinolinium Compounds Biochim Biophys Acta 292(2):444;1973 NLM IDX NLM M0045050 ethyl red C0601959 1-ethyl-2-(1-ethyl-4-methenyl)quinolinylquinolinium iodide 634-21-9 T075053 ethyl red C012210 BES 1976 01 01 2000 09 28 1994 1995 1996 1997 1998 1999 2000 2000A 2000B 2001 2002 buffer for physiological pH range; structure 9 *ALKANESULFONATES (76-93) *D017738 Alkanesulfonic Acids D002021 Buffers Anal Chem 48(9):1293;1976 NLM TWD TWD M0059105 BES C0053353 N,N-bis(2-hydroxyethyl)aminoethanesulfonic acid 10191-18-1 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T089108 BES C003945 ceramide hexasaccharide 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *GLYCOLIPIDS (73-76) CERAMIDES (73-76) OLIGOSACCHARIDES (73-76) *D006028 Glycosphingolipids J Biol Chem 248(9):3046;1973 NLM NLM M0045085 ceramide hexasaccharide C0601966 0 T075088 ceramide hexasaccharide C003948 amenorone 1973 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 oral contraceptive used in pregnancy test; contains above 2 cpds 0 CONTRACEPTIVES, ORAL (73-76) DRUG COMBINATIONS (73-76) *D004997 Ethinyl Estradiol *D005003 Ethisterone D003277 Contraceptives, Oral, Combined Nature 242(397):410;1973 NLM VSR NLM M0045089 amenorone C0601970 53568-84-6 T075092 amenorone C003949 hypotaurine 1973 01 01 1998 09 03 1998 1999 2000 2001 2002 intermediate in production of taurine in the liver; structure 134 *TAURINE (73-75) D013654 Taurine *Q000031 analogs ; derivatives Alabama J Med Sci 15(1):20;1978 Eur Urol 4:204;1978 Life Sci 1980;26(4):267 Life Sci 22:1789;1978 Nature 241(386):202;1973 Physiol Chem Phys 10(5):435;1978 Taurine (monograph) 67;1976 NLM SZM NLM M0045090 hypotaurine C0063235 2-aminoethanesulfinic acid 300-84-5 D000975 Antioxidants T075093 hypotaurine C003953 3,5-diacetyl-1,4-dihydrolutidine 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 secondary substrate for uricase-peroxidase system 1 *PYRIDINES (73-87) *D004095 Dihydropyridines Clin Chim Acta 44(2):159;1973 NLM NLM M0045095 3,5-diacetyl-1,4-dihydrolutidine C0047024 1079-95-4 T075098 3,5-diacetyl-1,4-dihydrolutidine C100268 ethamivan 1986 07 31 2000 09 28 1995 1996 1997 1998 1999 2000 2000A 2001 2002 minor descriptor (65-72); major descriptor (73-86); on-line search BENZAMIDES (66-86); INDEX MEDICUS search BENZAMIDES (65-72); ETHAMIVAN (73-86) 4 minor descriptor (65-72); major descriptor (73-86); file maintained to BENZAMIDES *D001549 Benzamides Eur Neurol 1983;22(suppl 1):116 PEH CCR CCR M0263261 ethamivan C0059692 304-84-7 T109 Organic Chemical T121 Pharmacologic Substance T293266 ethamivan Merck Index, 10th ed, #3667. USAN 1986, p.1311. T293265 etamivan C003960 megestranol 1973 01 01 1982 11 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains above 2 cpds 0 DRUG COMBINATIONS (73-76) *D008535 Megestrol *D008656 Mestranol D003277 Contraceptives, Oral, Combined Probl Endokrinol (Mosk) 191(2):87;1973 NLM VSR NLM M0045108 megestranol C0601978 8064-51-5 T075111 megestranol C003962 2-ethyl-2-aminopentanoic acid 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *AMINO ACIDS (73-75) D007930 Leucine *Q000031 analogs ; derivatives Can J Biochem 51(5):673;1973 NLM NLM M0045113 2-ethyl-2-aminopentanoic acid C0601979 L-Norvaline, 2-ethyl- 78737-63-0 T075116 2-ethyl-2-aminopentanoic acid C003963 cytidine-2'(3')-P-5'-puromycin 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PUROMYCIN (73-75) NUCLEOTIDES, CYCLIC (74-76) *D003597 Cytosine Nucleotides D011691 Puromycin *Q000031 analogs ; derivatives NLM NLM M0045114 cytidine-2'(3')-P-5'-puromycin C0601980 40951-29-9 T075117 cytidine-2'(3')-P-5'-puromycin C004155 N-methylhomopavine 1973 01 01 1988 11 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 poppy alkaloid of the pavine group; structure 0 BICYCLO COMPOUNDS (73-81) *D000470 Alkaloids J Org Chem 38(11):2099;1973 NLM RLS NLM M0045125 N-methylhomopavine C0601983 39013-26-8 M0045125 M0045124 T075128 N-methylhomopavine M0045124 6,11,12,13-tetrahydro-2,3,8,9-tetramethoxy-14-methyl-5H-dibenzo(a,e)cyclononen-5,11-imine C0601982 M0045125 M0045124 T075127 6,11,12,13-tetrahydro-2,3,8,9-tetramethoxy-14-methyl-5H-dibenzo(a,e)cyclononen-5,11-imine C004163 lacticolorin 1973 01 01 1981 01 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 phenolic glucoside ester; metabolite of Protea lacticolor Salisb.; structure 0 *GLYCOSIDES (73-75) BENZOATES (73-76) CATECHOLS (79-81) GLUCOSE (73-75) *D005960 Glucosides J Chem Soc (Perkin I) 6:638;1973 NLM BEJ NLM M0045138 lacticolorin C0601990 2-hydroxy-4-hydroxymethylphenyl-6-O-benzoyl- beta-D-glucopyranoside 41942-94-3 T075141 lacticolorin C004164 2,2-dimethyl-6 beta-phenylacetamidopenam-3 alpha-ol S-oxide 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CYCLIC S-OXIDES (73-76) *D010406 Penicillins J Chem Soc Perkin I 6:599;1973 NLM NLM M0045139 2,2-dimethyl-6 beta-phenylacetamidopenam-3 alpha-ol S-oxide C0601991 Benzeneacetamide, N-(2-hydroxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-, S-oxide, (2S-(2alpha,4beta,5alpha,6beta))- 41536-84-9 T075142 2,2-dimethyl-6 beta-phenylacetamidopenam-3 alpha-ol S-oxide C004167 angustoline 1973 01 01 1980 11 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 corynanthe alkaloid from Strychnos angustiflora; structure 0 *D000470 Alkaloids J Chem Soc (Perkin I) 1:13;1973 NLM RLS NLM M0045142 angustoline C0601994 40041-95-0 T075145 angustoline C004218 tylophorine 1973 01 01 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 5 *ALKALOIDS (73-76) PHENANTHRENES (73-82) *D007212 Indolizines Farmaco 28(5):399;1973 Indian J Med Res 69:513;1979 NLM TWD TWD M0045209 tylophorine C0077536 (S)-9,11,12,13,13a,14-hexahydro-2,3,6,7- tetramethoxydibenzo(f,h)pyrrolo(1,2-b)isoquinoline 482-20-2 T075212 tylophorine Merck Index, 9th ed, p. 1260, #9485 Negwer #4273 T075211 2,3,6,7-tetramethoxyphenanthro(9,10:6,7')indolizidine C004229 16 beta-hydroxynorgestrel 1973 01 01 2000 08 02 1998 1999 2000 2000A 2001 2002 urinary metabolite of norgestrel; RN given refers to (16beta,17alpha)-isomer; structure 0 *NORGESTREL (73-75) HYDROXYSTEROIDS (73-76) KETOSTEROIDS (73-75) D009644 Norgestrel *Q000031 analogs ; derivatives Acta Endocrinol 73(1):91;1973 NLM CCR CCR M0045228 16 beta-hydroxynorgestrel C0602021 13-ethyl-16 beta,17-dihydroxy-18,19-dinor- 17 alpha-pregn-4-en-20-yn-3-one 40915-03-5 T110 Steroid 40915-07-9 ((16alpha,17alpha)-isomer) 56298-27-2 ((8alpha,9beta,10alpha,13alpha,14beta,16beta)-isomer) 56324-27-7 ((8alpha,9beta,10alpha,13alpha,14beta,16alpha)-isomer) M0045228 M0308487 M0045228 M0308489 M0045228 M0308488 T075231 16 beta-hydroxynorgestrel M0308487 16 beta-hydroxynorgestrel, (16alpha,17alpha)-isomer C0888268 40915-07-9 T110 Steroid M0045228 M0308487 T338487 16 beta-hydroxynorgestrel, (16alpha,17alpha)-isomer 1999 08 18 M0308489 16 beta-hydroxynorgestrel, (8alpha,9beta,10alpha,13alpha,14beta,16alpha)-isomer C0888270 56324-27-7 T110 Steroid M0045228 M0308489 T338489 16 beta-hydroxynorgestrel, (8alpha,9beta,10alpha,13alpha,14beta,16alpha)-isomer 1999 08 18 M0308488 16 beta-hydroxynorgestrel, (8alpha,9beta,10alpha,13alpha,14beta,16beta)-isomer C0888269 56298-27-2 T110 Steroid M0045228 M0308488 T338488 16 beta-hydroxynorgestrel, (8alpha,9beta,10alpha,13alpha,14beta,16beta)-isomer 1999 08 18 C004175 hydroxymethylflavin 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 ALCOHOL, METHYL (73-75) ALCOHOL, METHYL/analogs (75-76) *D005415 Flavins J Chromatogr 78(1):105;1973 NLM NLM M0045149 hydroxymethylflavin C0082952 Benzo(g)pteridine-2,4(3H,10H)-dione, 10-((acetyloxy)methyl)-7,8-dimethyl- 35847-78-0 T075152 hydroxymethylflavin C074523 immunostimulatory human urinary protein 1992 06 12 2001 01 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from inflammatory mouse granuloma; protects normal mice against lethal Listeria monocytogenes infection; MW 43 kDa 2 *D006023 Glycoproteins Proc Natl Acad Sci U S A 1992 May 15;89(10):4358-62 RLS WXM WXM M0201174 immunostimulatory human urinary protein C0651534 0 T231179 immunostimulatory human urinary protein T231178 HGP 43 C074576 V protein, porcine rubulavirus 1992 06 16 2001 10 11 2002 encoded by the P gene of the porcine paramyxovirus La-Piedad-Michoacan-Mexico virus; has a conserved cysteine-rich C-terminal region; amino acid sequence given in first source 4 *D014764 Viral Proteins J Gen Virol 1992 May;73(Pt 5):1195-1200 RLS ags sjn M0201315 V protein, porcine rubulavirus C0651567 147652-41-3 T462598 V protein, porcine rubulavirus 2001 09 21 T231320 V protein, porcine paramyxovirus T231319 VPPPV C004186 carolenin 1974 01 01 1981 11 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 guaianolide--sesquiterpene lactone from Helenium autumnale L.; structure 0 LACTONES (74-81) *D012717 Sesquiterpenes J Org Chem 38(9):1722;1973 NLM NBM NLM M0045168 carolenin C0601997 38769-36-7 T075171 carolenin C073250 cadmium iodide 1992 04 02 2000 08 02 1997 1998 1999 2000 2000A 2001 2002 2 *CADMIUM (92-96) *D007454 Iodides *D019187 Cadmium Compounds Tsitol Genet 1991 Jul-Aug;25(4):63-7 BXB WXM WXM M0198110 cadmium iodide C0527076 7790-80-9 T131 Hazardous or Poisonous Substance T197 Inorganic Chemical T228115 cadmium iodide C004192 1,1'-polymethylenebis(thymine) 1973 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *THYMINE (73-75) POLYMERS (73-79) *D011108 Polymers D013941 Thymine *Q000031 analogs ; derivatives J Am Chem Soc 95(7):2320;1973 NLM NLM M0045176 1,1'-polymethylenebis(thymine) C0602002 0 T075179 1,1'-polymethylenebis(thymine) C004193 1,1'-trimethylenebis(thymine) 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *THYMINE (73-75) PROPANE (73-75) PROPANE/analogs (75-76) D013941 Thymine *Q000031 analogs ; derivatives J Am Chem Soc 95(7):2320;1973 NLM NLM M0045177 1,1'-trimethylenebis(thymine) C0602003 2,4(1H,3H)-Pyrimidinedione, 1,1'-(1,3-propanediyl)bis(5-methyl- 22917-75-5 T075180 1,1'-trimethylenebis(thymine) C074550 protein p12, African swine fever virus 1992 06 14 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; involved in virus attachment to the host cell; expressed by the African swine fever virus 8 *D014764 Viral Proteins D000358 African Swine Fever Virus J Virol 1992 Jun;66(6):3860-8 THA WXM WXM M0201246 protein p12, African swine fever virus C0168141 147994-32-9 T231251 protein p12, African swine fever virus T231250 ASF protein p12 C004196 hydroxymerodesmosine 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 functional crosslink of peptide chains in collagen 0 *AMINO ACIDS (73-75) D003895 Desmosine *Q000031 analogs ; derivatives D003094 Collagen Biochim Biophys Acta 310(1):130;1973 NLM RLS NLM M0045180 hydroxymerodesmosine C0063160 5-Undecenedioic acid, 2,10-diamino-5-(((5-amino-5-carboxy-2-hydroxypentyl)amino)methyl)- 42589-01-5 T075183 hydroxymerodesmosine C004198 fuberidazole 1973 01 01 1983 10 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 fumigant; structure 3 FURANS (73-82) PESTICIDES (73-75) *D001562 Benzimidazoles Chromatography 79(0):217;1973 NLM MGR NLM M0045182 fuberidazole C0060792 2-(2-furyl)benzimidazole 3878-19-1 T075185 fuberidazole C004911 ethomoxane 1969 01 01 2000 08 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 RN given refers to cpd without isomeric designation; structure 0 *DIOXINS (69-75) BUTYLAMINES (73-76) *D004146 Dioxanes NLM CCR CCR M0046112 ethomoxane C0602110 DL-8-ethoxy-2-butylaminomethyl-1,4-benzodioxan 3570-46-5 T109 Organic Chemical T121 Pharmacologic Substance 16509-23-2 ((+-)-isomer) 6038-78-4 (HCl) M0046112 M0308788 M0046112 M0308789 T076115 ethomoxane Merck Index, 9th ed, p. 493, #3671 Negwer #2464 M0308788 ethomoxane, (+-)-isomer C0888403 16509-23-2 T109 Organic Chemical T121 Pharmacologic Substance M0046112 M0308788 T338788 ethomoxane, (+-)-isomer 1999 08 18 M0308789 ethomoxane hydrochloride C0888404 6038-78-4 T109 Organic Chemical T121 Pharmacologic Substance M0046112 M0308789 T338789 ethomoxane hydrochloride 1999 08 18 C435188 1,2-dihydro-10-methoxy-2,2,4-trimethyl-5-(3-methylthiomethoxyphenyl)-5H-chromeno(3,4-f)quinoline 2001 09 21 2001 2002 a glucocorticoid receptor ligand; structure in first source 1 *D001578 Benzopyrans *D011804 Quinolines D008024 Ligands J Med Chem 2001 Aug 30;44(18):2879-85 THA THA M0399117 1,2-dihydro-10-methoxy-2,2,4-trimethyl-5-(3-methylthiomethoxyphenyl)-5H-chromeno(3,4-f)quinoline 0 T109 Organic Chemical T121 Pharmacologic Substance T462717 1,2-dihydro-10-methoxy-2,2,4-trimethyl-5-(3-methylthiomethoxyphenyl)-5H-chromeno(3,4-f)quinoline 2001 09 21 T462718 1,2-dihydro-MTMCQ 2001 09 21 C435189 N-(3-benzoyl-4-(2-(4-methylphenyl)acetylamino)phenyl)cysteinamide 2001 09 21 2001 2002 a farnesyltransferase inhibitor; structure in first source 1 D003545 Cysteine J Med Chem 2001 Aug 30;44(18):2886-99 THA THA M0399118 N-(3-benzoyl-4-(2-(4-methylphenyl)acetylamino)phenyl)cysteinamide 0 T109 Organic Chemical T121 Pharmacologic Substance T462719 N-(3-benzoyl-4-(2-(4-methylphenyl)acetylamino)phenyl)cysteinamide 2001 09 21 T462720 3-benzoyl-MPAAPCysNH2 2001 09 21 *aa C004219 6/137 1973 01 01 1986 07 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ALKYL SULFONATES (73-82) *D010648 Phenylacetates Farmaco 28(5):351;1973 NLM THA NLM M0045211 6/137 C0602013 0 M0045211 M0045210 T075214 6/137 M0045210 4-phenyl-alpha-methylphenylacetate gamma-propylsulfonate C0602012 M0045211 M0045210 T075213 4-phenyl-alpha-methylphenylacetate gamma-propylsulfonate C004225 oxypurinol ribosyl phosphate 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PURINONES (73-75) *D012265 Ribonucleotides D010117 Oxypurinol *Q000031 analogs ; derivatives J Biol Chem 248(11):3801;1973 NLM RLS NLM M0045223 oxypurinol ribosyl phosphate C0602020 31883-21-3 T075226 oxypurinol ribosyl phosphate C004226 cerebronic acid 1973 01 01 1982 01 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 *FATTY ALCOHOLS (73-75) *HYDROXY ACIDS (75-82) FATTY ACIDS (73-82) *D005227 Fatty Acids Biochim Biophys Acta 488:102;1977 J Biol Chem 248(11):4123;1973 NLM NBM NLM M0045224 cerebronic acid C0055109 2-hydroxytetracosanoic acid 544-57-0 T075227 cerebronic acid C051282 13-hydroxy-14,15-epoxyeicosa-5,8,11-trienoic acid 1987 02 27 2000 08 02 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 1 D015126 8,11,14-Eicosatrienoic Acid *Q000031 analogs ; derivatives Arch Biochem Biophys 1987;252(1):334 MEG TWD TWD M0145998 13-hydroxy-14,15-epoxyeicosa-5,8,11-trienoic acid C0629692 79595-80-5 T111 Eicosanoid T123 Biologically Active Substance T176003 13-hydroxy-14,15-epoxyeicosa-5,8,11-trienoic acid T176002 13H-14,15-EET C435190 N-((1-(4-chlorobenzyl)-4-methoxy-1H-indol-2-yl)methyl)propanamide 2001 09 21 2001 2002 an MT(2)-selective melatonin antagonist; structure in first soiurce 1 *D007211 Indoles D008550 Melatonin Q000037 antagonists ; inhibitors J Med Chem 2001 Aug 30;44(18):2900-12 THA THA M0399119 N-((1-(4-chlorobenzyl)-4-methoxy-1H-indol-2-yl)methyl)propanamide 0 T109 Organic Chemical T462721 N-((1-(4-chlorobenzyl)-4-methoxy-1H-indol-2-yl)methyl)propanamide 2001 09 21 T462722 chlorobenzyl-MIMP 2001 09 21 C004232 mercaptodextran 1973 01 01 1998 01 07 1998 1999 2000 2001 2002 3 *SULFHYDRYL COMPOUNDS (73-76) *D003911 Dextrans Biochem Pharmacol 22(10):1179;1973 NLM PML NLM M0045233 mercaptodextran C0065976 42612-66-8 T075236 mercaptodextran C004233 Vascoray 1973 01 01 1997 05 28 1997 1998 1999 2000 2001 2002 contrast medium of sodium iothalamate ; methylglucamine iothalamate 10 *AMINO SUGARS (73-79) *D007482 Iothalamate Meglumine *D007483 Iothalamic Acid D004338 Drug Combinations Angiology 24(5):288;1973 NLM TBT NLM M0045234 Vascoray C0078054 1-deoxy-1-(methylamino)-D-glucitol 3-(acetylamino)-2,4,6-triiodo-5-((methylamino)carbonyl) benzoate (salt), mixt. with 3-(acetylamino)-2,4,6- triiodo-5-((methylamino)carbonyl)benzoic acid monosodium salt 51819-38-6 T075237 Vascoray C004250 trichodesmine 1973 01 01 1997 06 09 1997 1998 1999 2000 2001 2002 3 *D000470 Alkaloids Farmatsiia 21(5):49;1972 NLM BMB NLM M0045235 trichodesmine C0376756 (13 alpha,14 alpha)-14,19-dihydro-12,13-dihydroxy-19-methylcrotalanan-11,15-dione 548-90-3 T075238 trichodesmine C004253 4-benzenesulfonyl-1,2,3,4-tetrahydro(1,4)diazepino(3,2,1-kl)phenoxazine 1973 01 01 1980 11 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 AZEPINES (73-81) SULFONES (73-76) *D010078 Oxazines Yakugaku Zasshi 93(1):20;1973 NLM BEJ NLM M0045239 4-benzenesulfonyl-1,2,3,4-tetrahydro(1,4)diazepino(3,2,1-kl)phenoxazine C0602022 0 T075242 4-benzenesulfonyl-1,2,3,4-tetrahydro(1,4)diazepino(3,2,1-kl)phenoxazine C004255 1,1-diphenylcyclopentanetetrone 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *KETONES (73-76) *D003517 Cyclopentanes Yakugaku Zasshi 93(1):1;1973 NLM NLM M0045242 1,1-diphenylcyclopentanetetrone C0602025 41998-32-7 T075245 1,1-diphenylcyclopentanetetrone C004256 amphodyn 1973 01 01 1983 08 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 horse chestnut extract ; hydroxyphenylethylamino-ethanol; improves venous circulation 0 PLANT EXTRACTS (73-83) *D004983 Ethanolamines D004338 Drug Combinations Z Allgemein Med 48(34):1608;1972 NLM ACS NLM M0045243 amphodyn C0483239 1336-78-3 T075246 amphodyn UD 18: 110m C004264 bromamphenicol 1973 01 01 1980 12 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ANTIBIOTICS (73-75) BROMINE (75-81) D002701 Chloramphenicol *Q000031 analogs ; derivatives Proc Nat Acad Sci 70(5):1423;1973 NLM BEJ NLM M0045252 bromamphenicol C0054089 threo-N-(beta hydroxy-alpha hydroxymethyl-p-nitrophenethyl)dibromoacetamide 40027-72-3 T075255 bromamphenicol Negwer 1372 C004265 N-bromoacetylphenylalanine 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PHENYLALANINE (73-76) ACETIC ACIDS (75-76) D010649 Phenylalanine *Q000031 analogs ; derivatives Proc Nat Acad Sci 70(5):1423;1973 NLM NLM M0045253 N-bromoacetylphenylalanine C0067861 L-Phenylalanine, N-(bromoacetyl)- 36753-68-1 T075256 N-bromoacetylphenylalanine C051283 11,14,15-trihydroxyeicosa-5,8,12-trienoic acid 1987 02 27 2000 08 02 1999 2000 2000A 2000B 2001 2002 3 D015126 8,11,14-Eicosatrienoic Acid *Q000031 analogs ; derivatives Arch Biochem Biophys 1987;252(1):334 MEG TWD TWD M0146002 11,14,15-trihydroxyeicosa-5,8,12-trienoic acid C0080537 79595-81-6 T111 Eicosanoid T123 Biologically Active Substance T176007 11,14,15-trihydroxyeicosa-5,8,12-trienoic acid T176004 11,14,15-THET T176005 11,14,15-THETA T176006 11,14,15-trihydroxyeicosatetraenoic acid C435191 (benzodioxan-6-yl)(2-trifluoromethyl-4-((3-carboxypyrrolidin-1-yl)carbonyl)ethenyl)phenyl sulfide 2001 09 21 2001 2002 a leukocyte function-associated antigen-1 (LFA-1)/ICAM-1 antagonist; structure in first source 1 *D009557 Nipecotic Acids *D013440 Sulfides J Med Chem 2001 Aug 30;44(18):2913-20 THA THA M0399120 (benzodioxan-6-yl)(2-trifluoromethyl-4-((3-carboxypyrrolidin-1-yl)carbonyl)ethenyl)phenyl sulfide 0 T109 Organic Chemical T121 Pharmacologic Substance T462723 (benzodioxan-6-yl)(2-trifluoromethyl-4-((3-carboxypyrrolidin-1-yl)carbonyl)ethenyl)phenyl sulfide 2001 09 21 T462724 benzodioxan-6-yl TCCEP sulfide 2001 09 21 C004270 phenyl N-methylacetimidate 1973 01 01 1980 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *IMINES (73-80) PHENYL ETHERS (74-80) *D007096 Imidoesters Biochemistry 12(13):2483;1973 NLM NLM M0045262 phenyl N-methylacetimidate C0602030 Ethanimidic acid, N-methyl-, phenyl ester 22084-79-3 T075265 phenyl N-methylacetimidate C004271 3-acetoxy-2,6-dinitropyridine 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D011725 Pyridines Biochemistry 12(13):2475;1973 NLM NLM M0045263 3-acetoxy-2,6-dinitropyridine C0602031 35666-27-4 T075266 3-acetoxy-2,6-dinitropyridine C004275 colanic acid 1973 01 01 1997 02 27 1997 1998 1999 2000 2001 2002 contains glucose, galactose, fucose, glucuronic acid 52 GLUCURONATES (73-82) *D011134 Polysaccharides D000942 Antigens, Bacterial D011135 Polysaccharides, Bacterial Ann Inst Pasteur (Lille) 22(0):25;1971 NLM BMB NLM M0045269 colanic acid C0056095 9012-87-7 M0045269 M0045268 T075272 colanic acid M0045268 M-antigen (bacterial) C0525107 M0045269 M0045268 T075271 M-antigen (bacterial) C074692 invariant surface glycoprotein 65 1992 06 23 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; from Trypanosoma brucei 2 *D008562 Membrane Glycoproteins *D015800 Protozoan Proteins J Biol Chem 1992 May 25;267(15):10797-803 BXB WXM WXM M0201596 invariant surface glycoprotein 65 C0168413 147338-68-9 T231601 invariant surface glycoprotein 65 T231600 ISG65 C004276 glutamylalanine 1973 01 01 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 5 ALANINE (73-75) GLUTAMATES (73-75) *D004151 Dipeptides Biochem Biophys Acta 304(2):363;1973 NLM TWD TWD M0045271 glutamylalanine C0061501 21064-18-6 T075274 glutamylalanine T075273 Glu-Ala C074703 outer membrane protein P2, Haemophilus influenzae type b 1992 06 24 2001 01 30 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence has been determined 12 *D001425 Bacterial Outer Membrane Proteins D000942 Antigens, Bacterial J Infect Dis 1992 Jun;165 Suppl 1:S86-9 BXB WXM WXM M0201615 outer membrane protein P2, Haemophilus influenzae type b C0168432 0 T231620 outer membrane protein P2, Haemophilus influenzae type b T231619 OMP P2-HI type b C004380 H 35-25 1972 01 01 2000 08 02 1995 1996 1997 1998 1999 2000 2000A 2001 2002 RN given refers to parent cpd; structure 16 *PROPANOLAMINES (76-80) PROPYLAMINES (72-76) D004809 Ephedrine *Q000031 analogs ; derivatives Acta Physiol Scand 102:459;1978 Acta Physiol Scand 97(1):88;1976 Br J Pharmacol 59(1):135;1977 Clin Sci Mol Med 48(Suppl 2):89;1975 Eur J Pharmacol 37(1):91;1976 J Pharm Pharmacol 29(3):184;1977 Res Vet Sci 1979;27(3):372 NLM CCR CCR M0045444 H 35-25 C0062036 benzenemethanol, 4-methyl-alpha-(1-((1-methylethyl)amino)ethyl)- 13549-60-5 T109 Organic Chemical T121 Pharmacologic Substance 13549-69-4 (HCl) 41599-59-1 (HCl(+-)-isomer) M0045444 M0045443 M0045444 M0308565 M0045444 M0308566 T075447 H 35-25 T075444 H-35-25 T075445 H35-25 M0045443 alpha-(1-(isopropylamino)ethyl)-4-methylbenzyl alcohol C0102362 T109 Organic Chemical T121 Pharmacologic Substance M0045444 M0045443 T075446 alpha-(1-(isopropylamino)ethyl)-4-methylbenzyl alcohol M0308565 H 35-25, hydrochloride C0888306 13549-69-4 T109 Organic Chemical T121 Pharmacologic Substance M0045444 M0308565 T338565 H 35-25, hydrochloride 1999 08 18 M0308566 H 35-25, hydrochloride, (+-)-isomer C0888307 41599-59-1 T109 Organic Chemical T121 Pharmacologic Substance M0045444 M0308566 T338566 H 35-25, hydrochloride, (+-)-isomer 1999 08 18 C435192 4-(5-((1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino)methyl)imidazol-1-ylmethyl)benzonitrile 2001 09 21 2001 2002 a farnesyltransferase inhibitor; structure in first source 1 *D007769 Lactams *D011760 Pyrrolidinones J Med Chem 2001 Aug 30;44(18):2933-49 THA THA M0399121 4-(5-((1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino)methyl)imidazol-1-ylmethyl)benzonitrile 0 T109 Organic Chemical T121 Pharmacologic Substance T462725 4-(5-((1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino)methyl)imidazol-1-ylmethyl)benzonitrile 2001 09 21 T462726 chlorobenzyl-OMIBCN 2001 09 21 C429280 PhpA protein 2001 06 22 2002 01 25 2001 2002 2002A PhpA-20 is a short form of PhpA; PhpA-79 is a potential vaccine candidate for treating pneumonia; GenBank AF340221 (PhpA), AF340222 (PhpA-79), and AF340223 (PhpA-20) 1 *D001426 Bacterial Proteins Infect Immun 2001 Jun;69(6):3827-36 THA TWD TWD M0391659 PhpA protein C0967130 0 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance T129 Immunologic Factor M0391659 M0391660 M0391659 M0391661 T452124 PhpA protein 2001 06 22 T452125 phpA gene product 2001 06 22 M0391660 phpA-20 gene product C0967131 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance T129 Immunologic Factor M0391659 M0391660 T452126 phpA-20 gene product 2001 06 22 M0391661 phpA-79 gene product C0967132 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance T129 Immunologic Factor M0391659 M0391661 T452127 phpA-79 gene product 2001 06 22 C004474 aminitrozole 1969 01 01 2001 07 23 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 10 ACETAMIDES (71-76) *D013844 Thiazoles NLM CCR CCR M0045544 aminitrozole C0051608 2-acetamido-5-nitrothiazole 140-40-9 81117-04-6 (mono-HF) M0045544 M0308588 T075547 aminitrozole Negwer 216 T075544 2-acetylamino-5-nitrothiazole T075545 nitazole T075546 nithiamide M0308588 aminitrozole monohydrofluoride C0951258 81117-04-6 M0045544 M0308588 T338588 aminitrozole monohydrofluoride 1999 08 18 C011908 melanoidin polymers 1976 01 01 2001 07 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 polymers consisting mainly of humic ; fulvic acids which make up major part of organic carbon reservoir in recent sediments; melanoidins also refer to dark colored substances formed by interaction of reducing sugars ; amino acids when heated 29 BENZOPYRANS (76-82) HUMIC ACIDS (76-82) *D011108 Polymers J Mol Evol 6(4):253;1975 NLM jmp jmp M0058549 melanoidin polymers C0065903 0 T109 Organic Chemical M0058549 M0058548 T088552 melanoidin polymers Hackh's Chemical Dictionary, 4th Ed p.413 M0058548 melanoidins C0127456 T109 Organic Chemical M0058549 M0058548 T088551 melanoidins C074748 SRB2 protein 1992 06 25 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; SRB2 reveals a functional link between RNA polymerase II CTD and TFIID 10 *D005656 Fungal Proteins *D014157 Transcription Factors D012441 Saccharomyces cerevisiae Cell 1992 May 29;69(5):883-94 BXB WXM WXM M0201708 SRB2 protein C0527171 147706-77-2 T231713 SRB2 protein T231712 SRB2 gene product C067407 14,15-episulfide eicosatrienoic acid 1991 03 21 2000 08 02 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 inhibits ionophore but not thrombin-induced platelet aggregation 2 D015126 8,11,14-Eicosatrienoic Acid *Q000031 analogs ; derivatives Mol Pharmacol 1991;39(2):114 RLS TWD TWD M0184763 14,15-episulfide eicosatrienoic acid C0080565 98893-66-4 T111 Eicosanoid T123 Biologically Active Substance M0184763 M0184762 T214768 14,15-episulfide eicosatrienoic acid M0184762 14,15-cis-episulfide-eicosatrienoic acid C0090370 T111 Eicosanoid T123 Biologically Active Substance M0184763 M0184762 T214767 14,15-cis-episulfide-eicosatrienoic acid C074768 rhp3+ protein 1992 06 26 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; homologous to yeast RAD3 and human ERCC-2 protein 1 *D005656 Fungal Proteins D004260 DNA Repair D012568 Schizosaccharomyces Nucleic Acids Res 1992 May 11;20(9):2327-34 BXB WXM WXM M0201747 rhp3+ protein C0651754 147756-90-9 T231752 rhp3+ protein T231751 rhp3+ gene product C008435 methyldithiocarbamate 1969 01 01 2001 07 24 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; carbathione refers to Na salt 34 *D013859 Thiocarbamates Bull Acad Pol Sci 22(5):329;1974 Bull Environ Contam Toxicol 22(3):400;1979 Contact Dermatitis 4(6):370;1978 Med Parazitol (Mosk) 45(2):186;1976 Veterinariia (12):28;1975 Veterinariia (3):79;1976 Wiad Parazytol 1981;27(4-5):599 NLM CCR CCR M0052285 methyldithiocarbamate C0066344 methylcarbamodithioic acid 144-54-7 D000871 Anthelmintics D000969 Antinematodal Agents D010575 Pesticides 137-41-7 (mono-K salt) 137-42-8 (Na salt) 37611-74-8 (Fe salt) 39680-90-5 (NH4 salt) 6734-80-1 (mono-Na salt.dihydrate) 79403-05-7 (Mg salt[2:1]) M0052285 M0310313 M0052285 M0310316 M0052285 M0310311 M0052285 M0310315 M0052285 M0310312 M0052285 M0052282 M0052285 M0310314 M0052285 M0052284 T082288 methyldithiocarbamate M0310313 iron methyldithiocarbamate C0951852 37611-74-8 M0052285 M0310313 T340313 iron methyldithiocarbamate 1999 08 18 M0310316 magnesium (2:1) methyldithiocarbamate C0969948 79403-05-7 M0052285 M0310316 T340316 magnesium (2:1) methyldithiocarbamate 1999 08 18 M0310311 monopotassium methyldithiocarbamate C0951851 137-41-7 M0052285 M0310311 T340311 monopotassium methyldithiocarbamate 1999 08 18 M0310315 monosodium methyldithiocarbamate dihydrate C0951854 6734-80-1 M0052285 M0310315 T340315 monosodium methyldithiocarbamate dihydrate 1999 08 18 M0310312 sodium methyldithiocarbamate C0127798 137-42-8 M0052285 M0310312 T340312 sodium methyldithiocarbamate 1999 08 18 T082284 methyldithiocarbamic acid sodium salt T082283 metham sodium T082282 metam sodium T082281 carbathione M0052282 Nematin C0132109 M0052285 M0052282 T082285 Nematin M0310314 methyldithiocarbamate, ammonium salt C0951853 39680-90-5 M0052285 M0310314 T340314 methyldithiocarbamate, ammonium salt 1999 08 18 M0052284 Vapam C0148179 M0052285 M0052284 T082287 Vapam C419106 alternative complement pathway-inhibiting protein 2001 01 30 2002 01 24 2001 2002 2002A inhibits the activation of the alternative complement pathway (ACP) of the human serum, was isolated from larval hemolymph of the silkworm, Bombyx mori; amino acid sequence in first source 1 *D019476 Insect Proteins D003170 Complement Pathway, Alternative Dev Comp Immunol 2001 Mar;25(2):89-100 SZM CCR CCR M0377456 alternative complement pathway-inhibiting protein C0963602 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T434556 alternative complement pathway-inhibiting protein 2001 01 30 T434557 ACPIP protein 2001 01 30 C088117 acetylleucine 1994 08 01 2002 01 25 2001 2001A 2001B 2001C 2002 2002A used for treating vestibular-related imbalance and vertigo; structure given in first source; RN refers to (L)-isomer 8 D007930 Leucine *Q000031 analogs ; derivatives Science 1994 Jul 8;265(5169):234-7 BMB TWD TWD M0233246 acetylleucine C0256552 1188-21-2 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance M0233246 M0391682 M0233246 M0366678 M0233246 M0391683 T263251 acetylleucine T263249 N-acetyl-L-leucine T263250 N-acetylleucine M0391682 acetyl-DL-leucine C0967150 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance M0233246 M0391682 T452156 acetyl-DL-leucine 2001 06 23 M0366678 Lasdol C0125321 0 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance M0233246 M0366678 T420017 Lasdol 2000 07 26 M0391683 Tanganil C0967151 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance M0233246 M0391683 T452157 Tanganil 2001 06 23 C067514 12-hydroxy-5,8,14-eicosatrienoic acid 1991 03 27 2000 08 02 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 structure given in first source 7 D015126 8,11,14-Eicosatrienoic Acid *Q000031 analogs ; derivatives Adv Prostaglandin Thromboxane Leukotriene Res 1991;21A:185 RLS TWD TWD M0185016 12-hydroxy-5,8,14-eicosatrienoic acid C0080556 117346-20-0 T111 Eicosanoid T123 Biologically Active Substance 117346-21-1 ((S-(Z,Z,Z))-isomer) 122210-62-2 ((Z,Z,Z)-isomer) M0185016 M0325091 M0185016 M0325092 T215021 12-hydroxy-5,8,14-eicosatrienoic acid T215020 12(R)DH-HETE M0325091 12-hydroxy-5,8,14-eicosatrienoic acid, (S-(Z,Z,Z))-isomer C0893039 117346-21-1 T111 Eicosanoid T123 Biologically Active Substance M0185016 M0325091 T355091 12-hydroxy-5,8,14-eicosatrienoic acid, (S-(Z,Z,Z))-isomer 1999 08 18 M0325092 12-hydroxy-5,8,14-eicosatrienoic acid, (Z,Z,Z)-isomer C0893040 122210-62-2 T111 Eicosanoid T123 Biologically Active Substance M0185016 M0325092 T355092 12-hydroxy-5,8,14-eicosatrienoic acid, (Z,Z,Z)-isomer 1999 08 18 C076449 L-lysine-lactamase 1992 10 01 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 *D000581 Amidohydrolases Ukr Biokhim Zh 1992 Jan-Feb;64(1):110-3 BVL CCR CCR M0205594 L-lysine-lactamase C0312213 EC 3.5.2.11 T235599 L-lysine-lactamase T235597 L-alpha-aminocaprolactam hydrolase T235598 L-lysinamidase C069476 hepoxillin A3-D 1991 07 26 2000 08 02 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 structure given in first source 1 D015126 8,11,14-Eicosatrienoic Acid *Q000031 analogs ; derivatives Biochim Biophys Acta 1991;1084(1):60 TPW TWD TWD M0189602 hepoxillin A3-D C0646425 135819-58-8 T111 Eicosanoid T123 Biologically Active Substance T219607 hepoxillin A3-D T219606 HxA3-D T219605 8,12-dihydroxy-11-cysteinylglycinyleicosa-5,9,14-trienoic acid C080037 15-hydroxy-5,8,11-eicosatrienoic acid 1993 04 04 2000 08 02 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 1 D015126 8,11,14-Eicosatrienoic Acid *Q000031 analogs ; derivatives Eicosanoids 1992;5(3-4):141-6 RLS TWD TWD M0214008 15-hydroxy-5,8,11-eicosatrienoic acid C0657686 139328-88-4 T111 Eicosanoid T123 Biologically Active Substance T244013 15-hydroxy-5,8,11-eicosatrienoic acid T244012 15-HEIA C085345 1-carbamoyl-L-amino acid amidohydrolase 1994 02 17 2001 01 30 1996 1997 1998 1999 2000 2001 2001A 2002 from Bacillus stearothermophilus; amino acid sequence given in first source 3 *D000581 Amidohydrolases Biosci Biotechnol Biochem 1993 Nov;57(11):1935-7 BVL CCR CCR M0226534 1-carbamoyl-L-amino acid amidohydrolase C0250872 EC 3.5.1.- T256539 1-carbamoyl-L-amino acid amidohydrolase T256538 carbamoyl L-AA amidohydrolase T256537 N-carbamyl-L-amino acid amidohydrolase C004438 adamon 1972 01 01 1980 10 23 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 BORNANES (72-81) *D002934 Cinnamates NLM NBM NLM M0045489 adamon C0050727 595-81-3 M0045489 M0045488 T075492 adamon M0045488 2-bornyl alpha, beta-dibromohydrocinnamate C0092672 M0045489 M0045488 T075491 2-bornyl alpha, beta-dibromohydrocinnamate C004440 ascaroside B 1968 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 glycoside components of ascarylic alcohol from Parascaris equorum 0 *GLYCOSIDES (68-82) *D006017 Glycolipids NLM VSR NLM M0045491 ascaroside B C0602060 11002-16-7 T075494 ascaroside B C080492 16-hydroxyheneicosatrienoic acid 1993 04 28 2000 08 02 1997 1998 1999 2000 2000A 2001 2002 used in the quantitation of hydroperoxy-eicosatetraenoic acid ; hydroxyeicosatetraenoic acids as indicators of lipid peroxidation 1 D015126 8,11,14-Eicosatrienoic Acid *Q000031 analogs ; derivatives Anal Biochem 1993 Feb 15;209(1):123-9 RLS TWD TWD M0215055 16-hydroxyheneicosatrienoic acid C0658188 131426-25-0 T111 Eicosanoid T123 Biologically Active Substance T245060 16-hydroxyheneicosatrienoic acid T245059 16-HHTE C004555 hydnocarpic acid 1973 01 01 2001 01 29 1998 1999 2000 2001 2001A 2002 cyclopentenyl fatty acid; component of chaulmoogra oil; structure; RN given refers to parent cpd(+)-isomer 3 CYCLOPENTANES (73-82) *D005227 Fatty Acids D010938 Plant Oils Am Rev Resp Dis 107(6):1022;1973 NLM TWD TWD M0045665 hydnocarpic acid C0063054 11-(2-cyclopenten-1-yl)undecanoic acid 459-67-6 5587-76-8 (Na salt) M0045665 M0308633 T075668 hydnocarpic acid M0308633 hydnocarpic acid, sodium salt C0951266 5587-76-8 M0045665 M0308633 T338633 hydnocarpic acid, sodium salt 1999 08 18 C074951 DnaZ protein 1992 07 07 2001 01 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 the gamma subunit of DNA polymerase III holoenzyme 4 *D004258 DNA Polymerase III Mol Gen Genet 1989 Apr;216(2-3):503-10 TPW WXM WXM M0202146 DnaZ protein C0114685 0 T232151 DnaZ protein T232150 DnaZ gene product C043636 zatebradine 1984 12 31 2000 09 28 1996 1997 1998 1999 2000 2000A 2001 2002 bradycardic agent; structure given in first source 93 *D001552 Benzazepines Eur J Pharmacol 1984;104(1-2):9 RLS CCR CCR M0128281 zatebradine C0208084 85175-67-3 T109 Organic Chemical T121 Pharmacologic Substance D002316 Cardiotonic Agents 91940-87-3 (HCl) M0128281 M0128279 M0128281 M0321931 T158286 zatebradine USAN (1996) M0128279 UL-FS 49 C0077786 T109 Organic Chemical T121 Pharmacologic Substance M0128281 M0128279 T158284 UL-FS 49 T158285 UL-FS-49 M0321931 zatebradine hydrochloride C0956573 91940-87-3 T109 Organic Chemical T121 Pharmacologic Substance M0128281 M0321931 T351931 zatebradine hydrochloride 1999 08 18 T158283 1,3,4,5-tetrahydro-7,8-dimethoxy-3-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylimino)propyl)-2H-3-benzazepin-2-one hydrochloride C004470 butalbital 1969 01 01 2000 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 RN given refers to parent cpd 30 ALLYL COMPOUNDS (72-76) *D001463 Barbiturates J Chromatogr 116(1):194;1976 NLM CCR CCR M0045538 butalbital C0054234 5-allyl-5-isobutylbarbituric acid 77-26-9 T109 Organic Chemical T121 Pharmacologic Substance 23554-70-3 (mono-Na salt) M0045538 M0308587 T075541 butalbital Negwer 1505 T075540 allylbarbital M0308587 butalbital, monosodium salt C0951257 23554-70-3 T109 Organic Chemical T121 Pharmacologic Substance M0045538 M0308587 T338587 butalbital, monosodium salt 1999 08 18 C411503 2-aminomethylbenzoic acid 2000 08 02 2000 2001 2002 structure in first source 1 *D020185 Benzoic Acids J Org Chem 2000 Jun 16;65(12):3571-8 THA THA M0367176 2-aminomethylbenzoic acid C0916134 0 T109 Organic Chemical T420657 2-aminomethylbenzoic acid 2000 08 02 T420658 o-aminomethylbenzoic acid 2000 08 02 C042005 1-octanesulfonic acid 1984 08 14 2000 09 28 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 RN given refers to parent cpd 10 *ALKANESULFONATES (84-93) *D017738 Alkanesulfonic Acids Can J Physiol Pharmacol 1984;62(4):350 MEG TWD TWD M0124309 1-octanesulfonic acid C0044550 3944-72-7 T109 Organic Chemical T121 Pharmacologic Substance 19475-81-1 (NH4 salt) 5324-84-5 (Na salt) M0124309 M0124307 M0124309 M0321690 M0124309 M0321689 T154314 1-octanesulfonic acid T154311 1-octanesulfonate M0124307 n-octyl sulfate C0284843 T109 Organic Chemical T121 Pharmacologic Substance M0124309 M0124307 T154312 n-octyl sulfate T154313 n-octylsulfate M0321690 1-octanesulfonic acid, sodium salt C0956451 5324-84-5 T109 Organic Chemical T121 Pharmacologic Substance M0124309 M0321690 T351690 1-octanesulfonic acid, sodium salt 1999 08 18 M0321689 1-octanesulfonic acid, ammonium salt C0956450 19475-81-1 T109 Organic Chemical T121 Pharmacologic Substance M0124309 M0321689 T351689 1-octanesulfonic acid, ammonium salt 1999 08 18 C004528 benzarone 1972 01 01 2000 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 antihemorrhagic agent; structure 22 *BENZOFURANS (72-81) BENZOATES (72-76) D001553 Benzbromarone *Q000031 analogs ; derivatives Arzneim Forsch 1979;29(10):1578 NLM CCR CCR M0045624 benzarone C0053152 2-ethyl-3-(4'-hydroxybenzoyl)benzofuran 1477-19-6 T109 Organic Chemical T121 Pharmacologic Substance D005343 Fibrinolytic Agents T075627 benzarone Negwer 2742 T075626 benzaron T075625 EHBB C006498 17-amino-4-azaandrostane 1974 01 01 2001 01 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 AZA COMPOUNDS (74-75) AZASTEROIDS (75-81) *D000731 Androstanes J Pharm Sci 1974 Jan;63(1):19-23 NLM TWD TWD M0049094 17-amino-4-azaandrostane C0602751 33208-74-1 T079097 17-amino-4-azaandrostane T079096 17 beta-amino-4-aza-5 alpha-androstane C004917 ethohexadiol 1969 01 01 2000 08 03 1996 1997 1998 1999 2000 2000A 2001 2002 insect repellent, moderately irritating to eyes, mucous membranes, but not to skin; RN given refers to cpd without isomeric designation; structure 13 ALCOHOLS, HEXYL (69-82) *D006018 Glycols D012997 Solvents NLM CCR CCR M0046120 ethohexadiol C0059726 94-96-2 T109 Organic Chemical T131 Hazardous or Poisonous Substance 4780-68-1 ((threo)-isomer) M0046120 M0308790 T076123 ethohexadiol Merck Index, 9th ed, p. 492, #3669 T076122 ethyl hexanediol T076121 2-ethyl-1,3-hexanediol M0308790 ethohexadiol, (threo)-isomer C0888405 4780-68-1 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0046120 M0308790 T338790 ethohexadiol, (threo)-isomer 1999 08 18 C074979 rice major allergenic protein 1992 07 08 2001 01 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; shows similarities to members of alpha-amylase/trypsin inhibitor family, such as barley trypsin inhibitor and wheat alpha-amylase inhibitor 2 *D010940 Plant Proteins D000485 Allergens D012275 Oryza sativa FEBS Lett 1992 May 18;302(3):213-6 THA WXM WXM M0202204 rice major allergenic protein C0379407 147097-22-1 T232209 rice major allergenic protein T232208 major RAP C006499 4-aminoazotoluene 1975 01 01 2001 01 30 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 not carcinogenic 1 *AZO COMPOUNDS (75-81) TOLUENE (75-81) D010128 p-Aminoazobenzene *Q000031 analogs ; derivatives Biull Eksp Biol Med 78(12):62;1974 NLM TWD TWD M0049096 4-aminoazotoluene C0602753 41576-40-3 T079099 4-aminoazotoluene T079098 p-aminoazotoluene C075019 lambda RAL-1 protein 1992 07 10 2001 01 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; homologous to human 46-kD Ro/SS-A autoantigen (calreticulin) 1 *D015801 Helminth Proteins D000947 Antigens, Helminth D017181 Onchocerca volvulus J Clin Invest 1992 Jun;89(6):1945-51 BXB WXM WXM M0202287 lambda RAL-1 protein C0652013 136251-99-5 T232292 lambda RAL-1 protein T232291 lambdaRAL-1 antigen C015763 cumene 1978 01 01 2000 09 28 1998 1999 2000 2000A 2001 2002 33 *D001555 Benzene Derivatives Gig Sanit 12:78;1977 Gig Sanit 2:81;1978 J Chromatogr 154(2):282;1978 NLM CCR CCR M0065269 cumene C0056587 98-82-8 T109 Organic Chemical T095272 cumene T095269 2-phenylpropane T095271 isopropylbenzene T095270 cumol C006503 4-aminobenzyl alcohol 1974 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *ALCOHOLS (74-75) *BENZYL COMPOUNDS (74-75) *D001592 Benzyl Alcohols Biochim Biophys Acta 327(1):11;1973 NLM TWD TWD M0049104 4-aminobenzyl alcohol C0602758 623-04-1 T079107 4-aminobenzyl alcohol T079106 p-aminobenzyl alcohol C004554 2,4,6-tribromophenol 1973 01 01 2001 08 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd 19 BISMUTH (73-82) *D010636 Phenols Farmatsiia 25(2):75;1976 Lancet II(7819):45;1973 Vestn Khir 121(8):84;1978 NLM CCR CCR M0045664 2,4,6-tribromophenol C0045436 118-79-6 5175-83-7 (Bi(3+) salt) M0045664 M0308632 M0045664 M0045662 M0045664 M0045663 T075667 2,4,6-tribromophenol Merck 9th ed, p. 169, #1317 M0308632 2,4,6-tribromophenol, bismuth (3+) salt C0971912 5175-83-7 M0045664 M0308632 T338632 2,4,6-tribromophenol, bismuth (3+) salt 1999 08 18 M0045662 bismuth tribromophenate C0106555 M0045664 M0045662 T075665 bismuth tribromophenate M0045663 Xeroform C0148970 M0045664 M0045663 T075666 Xeroform C004535 benzylmandelate 1970 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 BENZYL COMPOUNDS (73-76) *D008333 Mandelic Acids NLM NLM M0045631 benzylmandelate C0602066 890-98-2 T075634 benzylmandelate C004547 thyronamine 1973 01 01 1983 07 14 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN given refers to parent cpd 1 *PHENETHYLAMINES (73-75) PHENYL ETHERS (74-75) D013970 Thyronines *Q000031 analogs ; derivatives Eur J Pharmacol 22(2):141;1973 NLM ACS NLM M0045651 thyronamine C0076640 500-78-7 5221-18-1 (HCl) M0045651 M0045650 M0045651 M0308625 T075654 thyronamine Negwer, 5th ed, #2485 M0045650 p-(p-(2-aminoethyl)phenoxy)phenol C0134560 M0045651 M0045650 T075653 p-(p-(2-aminoethyl)phenoxy)phenol M0308625 HCl of thyronamine C0894598 5221-18-1 M0045651 M0308625 T338625 HCl of thyronamine 1999 08 18 C004549 3-bromo-5,7-dimethylpyrazolo(1,5-a)pyrimidine 1973 01 01 1982 01 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 PHOSPHODIESTERASES/*antag (73-78) PYRAZOLES (73-82) *D011743 Pyrimidines Arch Surg 107(1):12;1973 NLM NBM NLM M0045655 3-bromo-5,7-dimethylpyrazolo(1,5-a)pyrimidine C0047262 41945-37-3 T075658 3-bromo-5,7-dimethylpyrazolo(1,5-a)pyrimidine C004551 TES 1974 01 01 1982 06 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 26 *METHANESULFONATES (74-77) ALCOHOL, METHYL (74-77) D014325 Tromethamine *Q000031 analogs ; derivatives D002021 Buffers Aust J Biol Sci 25(5):1047;1973 NLM ESH NLM M0045658 TES C0076172 N-tris(hydroxymethyl)methyl-2-aminomethane sulfonate 7365-44-8 T075661 TES C004552 nagilactone C 1973 01 01 1983 08 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 norditerpene lactone isolated from leaves of Podocarpus; structure 2 LACTONES (73-81) *D004224 Diterpenes Aust J Biol Sci 25(5):1025 Gan 66(5):587;1975 NLM DLJ NLM M0045659 nagilactone C C0068368 24338-53-2 19891-50-0 (nagilactone A) 19891-51-1 (nagilactone B) 19891-53-3 (nagilactone D) 36895-12-2 (nagilactone E) 36912-00-2 (nagilactone F) M0045659 M0308627 M0045659 M0308628 M0045659 M0308629 M0045659 M0308630 M0045659 M0308631 T075662 nagilactone C M0308627 nagilactone A of nagilactone C C0894600 19891-50-0 M0045659 M0308627 T338627 nagilactone A of nagilactone C 1999 08 18 M0308628 nagilactone B of nagilactone C C0894601 19891-51-1 M0045659 M0308628 T338628 nagilactone B of nagilactone C 1999 08 18 M0308629 nagilactone D of nagilactone C C0894602 19891-53-3 M0045659 M0308629 T338629 nagilactone D of nagilactone C 1999 08 18 M0308630 nagilactone E of nagilactone C C0894603 36895-12-2 M0045659 M0308630 T338630 nagilactone E of nagilactone C 1999 08 18 M0308631 nagilactone F of nagilactone C C0894604 36912-00-2 M0045659 M0308631 T338631 nagilactone F of nagilactone C 1999 08 18 C060262 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone 1989 08 14 2001 08 17 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 ubiquinol analog 17 D014451 Ubiquinone *Q000031 analogs ; derivatives Biochemistry 1989;28(7):3031 TPW CCR CCR M0167513 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone C0245763 55486-00-5 T197518 2,3-dimethoxy-5-methyl-6-decyl-1,4-benzoquinone T197515 2,3-DMDB T197516 decyl-ubiquinone T197517 decylubiquinone C004556 erythro-2,3-dihydroxyhexacosanoic acid 1973 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *FATTY ALCOHOLS (73-75) *HYDROXY ACIDS (75-82) GLYCOLS (73-76) *D005227 Fatty Acids Lipids 8(5):325;1973 NLM VSR NLM M0045666 erythro-2,3-dihydroxyhexacosanoic acid C0602070 Hexacosanoic acid, 2,3-dihydroxy-, (R*,R*)- 43054-35-9 T075669 erythro-2,3-dihydroxyhexacosanoic acid C004557 cochliodinol 1973 01 01 1984 02 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 antibiotic from Chaetomium cochliodes (Ascomycetes); structure 1 *ANTIBIOTICS (73-79) INDOLES (79-82) D007211 Indoles D009183 Mycotoxins Lipids 8(5):312;1973 NLM DLJ NLM M0045667 cochliodinol C0056055 2,5-dihydroxy-3,6-bis(5-(3-methyl-2-butenyl)-1H- indol-3-yl)-2,5-cyclohexadiene-1,4-dione 11051-88-0 T075670 cochliodinol C004559 S-benzyl-L-cysteine-4'-nitroanilide 1973 01 01 1980 12 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 substrate for cystine aminopeptidase 9 *CYSTEINE (73-75) ANILIDES (73-81) NITRO COMPOUNDS (73-76) D003545 Cysteine *Q000031 analogs ; derivatives Clin Chem 19(7):756;1973 Jpn J Clin Pathol 23(6):415;1975 NLM BEJ NLM M0045669 S-benzyl-L-cysteine-4'-nitroanilide C0073857 7436-62-6 T075672 S-benzyl-L-cysteine-4'-nitroanilide C413662 red fluorescent protein 2000 09 28 2000 09 28 2000 2000A 2000B 2001 2002 amino acid sequence in first source 42 *D008164 Luminescent Proteins FEBS Lett 2000 Aug 18;479(3):127-30 BMB BMB BMB M0370310 red fluorescent protein C0960938 0 T116 Amino Acid, Peptide, or Protein T425307 red fluorescent protein 2000 09 28 T425314 drFP583 2000 09 28 T425315 ds red protein 2000 09 28 T425309 dsFP593 2000 09 28 T425308 FP593 2000 09 28 C413664 abt, Buthus martensi Karsch 2000 09 28 2000 2001 2002 a neurotoxic protein from the venom of Chinese scorpion Buthus martensi Karsch; MW 7212 Da; amino acid sequence in first source; GenBank AF241269 1 *D012604 Scorpion Venoms FEBS Lett 2000 Aug 18;479(3):136-40 BMB BMB M0370312 abt, Buthus martensi Karsch C0960940 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T131 Hazardous or Poisonous Substance T425316 abt, Buthus martensi Karsch 2000 09 28 T425317 BmK abT 2000 09 28 C004567 diethyl malonimidate 1973 01 01 1999 07 19 1999 2000 2001 2002 0 *IMIDES (73-80) MALONATES (73-82) *D007096 Imidoesters Biochem Biophys Res Comm 52(1):35;1973 Biochim Biophys Acta 567(2):401;1979 NLM BQV NLM M0045685 diethyl malonimidate C0057932 10344-69-1 T075688 diethyl malonimidate C089378 rhoifolin 1994 10 10 2001 09 05 2002 from many plants 1 *D004187 Disaccharides *D005419 Flavones *D006027 Glycosides D010944 Plants J Chromatogr B Biomed Appl 1994 May 13;655(2):300-4 THA ssb sjn M0236314 rhoifolin C0259178 4',5,7-trihydroxyflavone-7-rhamnoglucoside 17306-46-6 T109 Organic Chemical T121 Pharmacologic Substance T266319 rhoifolin C004573 1,1-dichloro-2,2-bis(5-chloro-2-methoxyphenyl)ethylene 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 DDE analog; structure 0 *INSECTICIDES, ORGANOCHLORINE (73-75) ALKENES (73-75) METHYL ETHERS (75-76) D003633 DDE *Q000031 analogs ; derivatives Int J Environ Anal Chem 1(4):301;1972 NLM NLM M0045697 1,1-dichloro-2,2-bis(5-chloro-2-methoxyphenyl)ethylene C0602073 35374-20-0 T075700 1,1-dichloro-2,2-bis(5-chloro-2-methoxyphenyl)ethylene C004704 cyclobenzaprine 1973 01 01 2000 09 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 RN given refers to parent cpd; Lisseril is synonymous for HCl; structure 71 *DIBENZOCYCLOHEPTENES (73-79) PROPYLAMINES (73-76) D000639 Amitriptyline *Q000031 analogs ; derivatives Arch Phys Med Rehabil 59(2):58;1978 Drug Metab Dispos 6(2):184;1978 Drug Metab Rev 5(2):197;1976 J Chromatogr 124(1):164;1976 J Chromatogr 131:357;1977 J Clin Pharmacol 17(11-12):719;1977 J Pharm Sci 65(6):815;1976 JAMA 240(11):1151;1978 Life Sci 16:1309;1975 Med Lett 20(2):12;1977 Neuropharmacology 14(9):675;1975 Neuropharmacology 15:643;1976 Neuropharmacology 17(7):445;1978 Neuropharmacology 17(9):721;1978 Neuropharmacology 1980;19(2):221 Proc West Pharmacol Soc 1979;22:31 NLM CCR CCR M0045849 cyclobenzaprine C0056732 N,N-dimethyl-3-(dibenzo(a,d)cycloheptene-4-ylidene)propylamine 303-53-7 T109 Organic Chemical T121 Pharmacologic Substance D000929 Antidepressive Agents, Tricyclic D009125 Muscle Relaxants, Central D014149 Tranquilizing Agents 6202-23-9 (HCl) M0045849 M0045847 M0045849 M0308678 M0045849 M0045848 T075852 cyclobenzaprine Merck Index, 9th ed, p. 354, #2718 M0045847 Flexeril C0728797 T109 Organic Chemical T121 Pharmacologic Substance M0045849 M0045847 T075850 Flexeril M0308678 cyclobenzaprine hydrochloride C0125988 6202-23-9 T109 Organic Chemical T121 Pharmacologic Substance M0045849 M0308678 T338678 cyclobenzaprine hydrochloride 1999 08 18 M0045848 Lisseril C0936055 T109 Organic Chemical T121 Pharmacologic Substance M0045849 M0045848 T075851 Lisseril C004581 centalun 1970 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ALKYNES (70-76) *D006018 Glycols NLM NLM M0045707 centalun C0602074 3-methyl-4-phenyl-1-butyne-3,4-diol 2033-94-5 T075710 centalun C111685 3,5-dinitro-2-tyrosine 1998 05 02 2001 08 17 1998 1999 2000 2001 2001A 2002 structure in first source 1 D014443 Tyrosine *Q000031 analogs ; derivatives J Med Chem 1998 Mar 26;41(7):1034-41 THA CCR CCR M0289121 3,5-dinitro-2-tyrosine C0673681 0 T319126 3,5-dinitro-2-tyrosine T319124 3,5-dinitro-o-tyrosine T319125 3,5-dinitro-ortho-tyrosine T319123 2-hydroxy-3,5-dinitrophenylalanine C004690 coclaurine 1969 01 01 2000 08 02 1998 1999 2000 2000A 2001 2002 RN given refers to (S)-isomer; structure 5 BENZYL CPDS (73-76) *D007546 Isoquinolines NLM CCR CCR M0045826 coclaurine C0056056 1,2,3,4-tetrahydro-1-(p-hydroxybenzyl)-6-methoxy-7-isoquinolinol 486-39-5 T109 Organic Chemical 2033-08-1 ((+-)-isomer) 2196-60-3 ((R)-isomer) M0045826 M0308674 M0045826 M0308675 T075829 coclaurine Merck Index, 9th ed, p. 315, #2416 M0308674 coclaurine, (+-)-isomer C0888346 2033-08-1 T109 Organic Chemical M0045826 M0308674 T338674 coclaurine, (+-)-isomer 1999 08 18 M0308675 coclaurine, (R)-isomer C0888347 2196-60-3 T109 Organic Chemical M0045826 M0308675 T338675 coclaurine, (R)-isomer 1999 08 18 C004822 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide 1973 01 01 2000 08 03 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 metabolite of carbamazepine; RN given refers to cpd without isomeric designation; structure 39 *DIBENZAZEPINES (73-75) D002220 Carbamazepine *Q000031 analogs ; derivatives Clin Pharmacol Anti-Epileptic Drugs W3--W0925(1974 c):159-66;1974 J Med Chem 16(6):703;1973 NLM CCR CCR M0046028 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide C0044644 35079-97-1 T109 Organic Chemical T121 Pharmacologic Substance 106680-78-8 ((trans-(+-))-isomer) 106758-94-5 ((10S,trans)-isomer) 58955-93-4 ((trans)-isomer) 58955-94-5 ((cis)-isomer) M0046028 M0308742 M0046028 M0308744 M0046028 M0308743 M0046028 M0308741 M0046028 M0046020 M0046028 M0046023 T076031 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide T076020 10,11-dihydro-10,11-dihydroxycarbamazepine T076022 10,11-dihydroxy-10,11-dihydrocarbamazepine T076028 carbamazepine-10,11-diol T076030 carbazepine 10,11-diol T076024 CBZ-diol T076025 CBZD M0308742 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide, (10S,trans)-isomer C0888388 106758-94-5 T109 Organic Chemical T121 Pharmacologic Substance M0046028 M0308742 T338742 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide, (10S,trans)-isomer 1999 08 18 M0308744 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide, (cis)-isomer C0888389 58955-94-5 T109 Organic Chemical T121 Pharmacologic Substance M0046028 M0308744 T338744 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide, (cis)-isomer 1999 08 18 M0308743 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide, (trans)-isomer C0108362 58955-93-4 T109 Organic Chemical T121 Pharmacologic Substance M0046028 M0308743 T338743 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide, (trans)-isomer 1999 08 18 T076021 10,11-dihydro-10,11-transdihydroxycarbamazepine T076029 carbamazepine-10,11-transdiol M0308741 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide, (trans-(+-))-isomer C0888387 106680-78-8 T109 Organic Chemical T121 Pharmacologic Substance M0046028 M0308741 T338741 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide, (trans-(+-))-isomer 1999 08 18 M0046020 10,11-dihydroxycarbamazepine C0089919 T109 Organic Chemical T121 Pharmacologic Substance M0046028 M0046020 T076023 10,11-dihydroxycarbamazepine M0046023 CGP 10,000 C0109189 T109 Organic Chemical T121 Pharmacologic Substance M0046028 M0046023 T076026 CGP 10,000 T076027 CGP-10,000 C004601 quinhydrone 1971 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 4 *D006873 Hydroquinones J Am Chem Soc 98(8):2287;1976 NLM NLM M0045716 quinhydrone C0072868 106-34-3 T075719 quinhydrone Merck, 9th ed, #7848 C004663 chloropropylate 1969 01 01 2000 12 14 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *D001561 Benzilates NLM TWD TWD M0045801 chloropropylate C0055444 isopropyl 4,4'-dichlorobenzilate 5836-10-2 T109 Organic Chemical T131 Hazardous or Poisonous Substance T075804 chloropropylate C035943 tetrocarcin F-1 1982 11 18 2001 08 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from Micromonospora chalcea KY 11091; structure given in first source 1 ANTIBIOTICS (82-87) GLYCOSIDES (82-87) *D000901 Antibiotics, Aminoglycoside J Antiobiot (Tokyo) 1982;35(8):979 VSR jmp jmp M0109813 tetrocarcin F-1 C0617115 Tetronolide, 10-O-(2,3,4,6-tetradeoxy-4-((methoxycarbonyl)amino)-3-C-methyl-3-nitrohexopyranosyl)- 81319-50-8 T109 Organic Chemical T195 Antibiotic T139817 tetrocarcin F-1 T139816 Tetronolide, 10-O-(2,3,4,6-tetradeoxy-4-((methoxycarbonyl)amino)-3-C-methyl-3-nitrohexopyranosyl)- C045483 valorphin 1985 07 01 2000 09 18 1995 1996 1997 1998 1999 2000 2000A 2001 2002 structure given in first source 3 D000218 Adamantane *Q000031 analogs ; derivatives Neuropeptides 1985;5(4-6):387 MEG TWD TWD M0132227 valorphin C0164301 68163-03-1 T109 Organic Chemical T121 Pharmacologic Substance M0132227 M0132226 T162232 valorphin M0132226 4-(2-(2-chlorophenyl)ethyl)amino-8-methoxy-3,10-dimethyl-2,9-dioxatricyclo(4,3,1,0(3,7))decane C0164300 T109 Organic Chemical T121 Pharmacologic Substance M0132227 M0132226 T162231 4-(2-(2-chlorophenyl)ethyl)amino-8-methoxy-3,10-dimethyl-2,9-dioxatricyclo(4,3,1,0(3,7))decane C004711 dicyandiamido 1969 01 01 2001 03 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 21 NITRILES (69-82) *D006146 Guanidines J Animal Sci 45(6):1397;1977 NLM CCR CCR M0045854 dicyandiamido C0057888 461-58-5 40529-30-4 (sulfate) M0045854 M0308680 T075857 dicyandiamido T075856 cyanoguanidine M0308680 dicyandiamido sulfate C0951286 40529-30-4 M0045854 M0308680 T338680 dicyandiamido sulfate 1999 08 18 C047128 cyclomaltoheptaose-1-adamantanemethanol 1986 02 04 2000 09 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 1 *D003505 Cyclodextrins D000218 Adamantane *Q000031 analogs ; derivatives Carbohydr Res 1985;142(1):21 MEG TWD TWD M0136253 cyclomaltoheptaose-1-adamantanemethanol C0625802 101412-93-5 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T166258 cyclomaltoheptaose-1-adamantanemethanol T166257 CMH-AM C057525 perfluoromethyladamantane 1988 11 30 2000 09 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 2 *D005466 Fluorocarbons D000218 Adamantane *Q000031 analogs ; derivatives Biomater Artif Cells Artif Organs 1988;16(1-3):443 TPW TWD TWD M0160928 perfluoromethyladamantane C0070401 60096-00-6 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0160928 M0160927 T190933 perfluoromethyladamantane M0160927 F-MA C0117140 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0160928 M0160927 T190932 F-MA C432845 HBME-1 antigen 2001 08 17 2001 2002 human mesothelial antigen tumor marker 8 *D014408 Tumor Markers, Biological D008654 Mesothelioma Am J Clin Pathol 2001 Aug;116(2):253-62 SZM SZM M0395768 HBME-1 antigen C0968671 0 T129 Immunologic Factor T130 Indicator, Reagent, or Diagnostic Aid T457732 HBME-1 antigen 2001 08 17 T457733 human mesothelial antigen 2001 08 17 C004636 1,3-cyclohexanedione 1968 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 6 CYCLOHEXANES (68-75) KETONES (68-75) *D003512 Cyclohexanones Biochem Biophys Res Commun 82(3):1013;1978 Biochemistry 17(23):4927;1978 J Biol Chem 252(11):3876;1977 Wiad Parazitol 24(6):687;1978 NLM NLM M0045758 1,3-cyclohexanedione C0043906 504-02-9 T075761 1,3-cyclohexanedione C036098 Testoviron-depot 1982 11 29 2001 08 17 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 combination of testosterone propionate ; testosterone enanthate 2 *D013739 Testosterone D004338 Drug Combinations D003692 Delayed-Action Preparations Clin Endocrinol Metab 1982;11(3):625 VSR jmp jmp M0110194 Testoviron-depot C0163860 54175-25-6 M0110194 M0110193 T140198 Testoviron-depot T457734 Testoviron Depot 2001 08 17 M0110193 Testenate C0163859 M0110194 M0110193 T140197 Testenate C094149 robustaflavone-7''-methyl ether 1995 07 17 2001 03 27 1996 1997 1998 1999 2000 2001 2001A 2002 isolated from Podocarpus imbricatus 1 *D005419 Flavones D004365 Drugs, Chinese Herbal Chung Kao Chung Yao Tsa Chih 1995 Feb;20(2):105-6 PML TWD TWD M0248094 robustaflavone-7''-methyl ether C0298728 0 T278099 robustaflavone-7''-methyl ether T278098 robustaflavone-7''-OMe C094159 A 86719.1 1995 07 17 2001 03 27 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure in first source 1 *D011728 Pyridones *D011807 Quinolizines Antimicrob Agents Chemother 1995 Apr;39(4):850-3 THA TWD TWD M0248113 A 86719.1 C0298745 0 T278118 A 86719.1 T278117 A-86719.1 C057578 perfluoroadamantane 1988 12 02 2000 09 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 1 D000218 Adamantane *Q000031 analogs ; derivatives Biomater Artif Cells Artif Organs 1988;16(1-3):607 TPW TWD TWD M0161032 perfluoroadamantane C0635317 69064-33-1 T109 Organic Chemical T121 Pharmacologic Substance T191037 perfluoroadamantane C006374 N-acetyldopamine 1974 01 01 2000 12 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 37 *DOPAMINE (74-75) D004298 Dopamine *Q000031 analogs ; derivatives J Insect Physiol 20(5):911;1974 NLM CCR CCR M0048885 N-acetyldopamine C0067694 2494-12-4 T116 Amino Acid, Peptide, or Protein 19456-69-0 (HBr) M0048885 M0309539 T078888 N-acetyldopamine M0309539 N-acetyldopamine hydrobromide C0951513 19456-69-0 T116 Amino Acid, Peptide, or Protein M0048885 M0309539 T339539 N-acetyldopamine hydrobromide 1999 08 18 C038555 3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin 1983 07 28 2000 12 20 1999 2000 2001 2001A 2002 more effective and has lower toxicity than doxorubicin 38 D004317 Doxorubicin *Q000031 analogs ; derivatives JAMA 1983;250(4):459 RLS CCR CCR M0115988 3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin C0046798 5,12-Naphthacenedione, 10-((3-(3-cyano-4-morpholinyl)-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)- 88254-07-3 T109 Organic Chemical T121 Pharmacologic Substance D000903 Antibiotics, Antineoplastic D003432 Cross-Linking Reagents 89196-08-7 ((S-(8S-cis))-isomer) M0115988 M0320989 M0115988 M0115983 T145992 3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin T145986 3'-(3-cyano-4-morpholinyl)-3'-deaminoadriamycin T145990 cyanomorpholino doxorubicin T145991 cyanomorpholinoadriamycin T145989 MRA-CN M0320989 3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin, (S-(8S-cis))-isomer C0956077 89196-08-7 T109 Organic Chemical T121 Pharmacologic Substance M0115988 M0320989 T350989 3'-deamino-3'-(3-cyano-4-morpholinyl)doxorubicin, (S-(8S-cis))-isomer 1999 08 18 M0115983 A 489 C0100706 T109 Organic Chemical T121 Pharmacologic Substance M0115988 M0115983 T145987 A 489 T145988 A-489 C004668 cinnopentazone 1969 01 01 1989 08 01 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D011724 Pyridazines NLM RJM RLS M0045810 cinnopentazone C0055766 2-pentyl-6-phenyl-1H-pyrazolo(1,2-a)quinoline- 1,3-(2H)-dione 2056-56-6 T075813 cinnopentazone C004673 deoxyfrenolicin 1979 01 01 1979 11 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 D009285 Naphthoquinones J Antibiotics 31(10):959;1978 NLM RLS NLM M0045812 deoxyfrenolicin C0057427 10023-11-7 T075815 deoxyfrenolicin C094161 SCH 51048 1995 07 17 2001 03 27 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 4 *D014230 Triazoles Antimicrob Agents Chemother 1995 Apr;39(4):996-7 THA TWD TWD M0248118 SCH 51048 C0298748 0 T278123 SCH 51048 T278122 SCH-51048 C004723 diamthazole 1969 01 01 2001 08 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 0 DIMETHYLAMINES (74-76) *D013844 Thiazoles NLM TWD TWD M0045880 diamthazole C0057720 6-(2-diethylaminoethylaminoethoxy)-2- dimethylaminobenzothiazole 95-27-2 136-96-9 (di-HCl) M0045880 M0045878 M0045880 M0308687 T075883 diamthazole Merck Index, 9th ed, p. 392, #2949 - di-HCl T075882 dimazole M0045878 amikazol C0102950 M0045880 M0045878 T075881 amikazol M0308687 diamthazole dihydrochloride C0951293 136-96-9 M0045880 M0308687 T338687 diamthazole dihydrochloride 1999 08 18 C411504 N-(1-pyrenyl)cyclohexylcarbodiimide 2000 08 03 2000 2001 2002 1 *D002234 Carbodiimides Biochemistry 2000 Jun 27;39(25):7531-7 BMB BMB M0367177 N-(1-pyrenyl)cyclohexylcarbodiimide C0916135 0 T109 Organic Chemical T420660 N-(1-pyrenyl)cyclohexylcarbodiimide 2000 08 03 T420661 N-PCHC cpd 2000 08 03 C432951 HLSG-2 protein 2001 08 17 2001 2002 isolated from the hard tick Haemoaphysalis longicornis; amino acid sequence in first source 1 *D012697 Serine Endopeptidases Insect Biochem Mol Biol 2001 Jun 22;31(8):817-25 THA THA M0395879 HLSG-2 protein C0968741 EC 3.4.21.- T116 Amino Acid, Peptide, or Protein T457923 HLSG-2 protein 2001 08 17 C432952 MHR4 protein 2001 08 17 2001 2002 isolated from the tobacco hornworm, Manduca sexta; ; GenBank AF288088 1 *D018160 Receptors, Cytoplasmic and Nuclear Insect Biochem Mol Biol 2001 Jun 22;31(8):827-37 THA THA M0395880 MHR4 protein C0968742 0 T192 Receptor T457924 MHR4 protein 2001 08 17 C094168 deoxyfluorouridylyl(3'-5')thymidine monophosphate 1995 07 18 2001 03 27 1996 1997 1998 1999 2000 2001 2001A 2002 1 *D015226 Dinucleoside Phosphates Nucleic Acids Res 1995 May 25;23(10):1810-5 PML TWD TWD M0248135 deoxyfluorouridylyl(3'-5')thymidine monophosphate C0298764 0 T278140 deoxyfluorouridylyl(3'-5')thymidine monophosphate T278139 d-FpT C004707 cyclohexylmethanol 1969 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ALCOHOL, METHYL (69-76) *D003510 Cyclohexanes NLM NLM M0045851 cyclohexylmethanol C0602080 100-49-2 T075854 cyclohexylmethanol C417085 MopB protein, Methylococcus 2000 12 20 2001 2002 amino acid sequence in first source 1 *D001425 Bacterial Outer Membrane Proteins D020619 Methylococcus capsulatus Arch Microbiol 2000 May-June;173(5-6):346-51 SXK SXK M0374962 MopB protein, Methylococcus C0962624 0 T116 Amino Acid, Peptide, or Protein M0374962 M0374963 T431482 MopB protein, Methylococcus 2000 12 20 M0374963 MopB protein, Methylococcus capsulatus C0971229 M0374962 M0374963 T431483 MopB protein, Methylococcus capsulatus 2000 12 20 C094171 4-S-cysteaminylcatechol 1995 07 18 2001 03 27 1995 1996 1997 1998 1999 2000 2001 2001A 2002 an activated form of 4-S-cysteaminylphenol; structure given in first source 2 D003543 Cysteamine *Q000031 analogs ; derivatives Cancer Res 1995 Jun 15;55(12):2603-7 PML TWD TWD M0248141 4-S-cysteaminylcatechol C0298771 0 T278146 4-S-cysteaminylcatechol T278145 4-S-CAC C432954 IcmR protein 2001 08 17 2001 2002 an IcmQ chaperone; isolated from Legionella pneumophila; amino acid sequence in first source 3 *D018832 Molecular Chaperones Infect Immun 1997 Dec;65(12):5057-66 THA THA M0395882 IcmR protein C0968744 0 T116 Amino Acid, Peptide, or Protein T457928 IcmR protein 2001 08 17 T457929 icmR gene product 2001 08 17 C004735 2,6-dimethylhydroquinone 1970 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 XYLENES (74-76) *D006873 Hydroquinones NLM NLM M0045887 2,6-dimethylhydroquinone C0602081 654-42-2 T075890 2,6-dimethylhydroquinone C066998 methoxy-morpholynil-doxorubicin 1991 02 26 2001 02 02 1998 1999 2000 2000A 2001 2001A 2002 structure in first source 31 D004317 Doxorubicin *Q000031 analogs ; derivatives Cancer Treat Rev 1990;17(2-3):133 TPW CCR CCR M0183753 methoxy-morpholynil-doxorubicin C0526711 108852-90-0 T109 Organic Chemical T121 Pharmacologic Substance D015249 Antibiotics, Anthracycline M0183753 M0183755 M0183753 M0358887 T213758 methoxy-morpholynil-doxorubicin T213755 3'-deamino-3'-(2(S)-methoxy-4-morpholinyl)doxorubicin T213759 methoxymorpholinoDX T213757 MMDOX T409574 MMDX 2000 03 17 M0183755 FCE 23762 C0082555 T109 Organic Chemical T121 Pharmacologic Substance M0183753 M0183755 T213760 FCE 23762 T213756 FCE-23762 M0358887 pnu 152243 C0904604 T109 Organic Chemical T121 Pharmacologic Substance M0183753 M0358887 T409573 pnu 152243 2000 03 17 C004838 dioxathion 1969 01 01 2000 08 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 RN given refers to cpd without isomeric designation; structure 12 *DIOXINS (69-75) DIOXANES (75-82) *D009946 Organothiophosphorus Compounds Bull Anim Health Prod Afr 1978;26(4):285 Bull Environ Contam Toxicol 16(6):646;1976 J Agric Food Chem 24(4):689;1976 J Agric Food Chem 24(6):1217;1976 NLM CCR CCR M0046047 dioxathion C0058336 S,S'-(p-dioxane-2,3-diyl)bis(O,O-diethylphosphorodithioate) 78-34-2 T115 Organophosphorus Compound T131 Hazardous or Poisonous Substance 16088-56-5 ((cis)-isomer) 16270-86-3 ((trans)-isomer) M0046047 M0308752 M0046047 M0308753 M0046047 M0046045 T076050 dioxathion Merck Index, 9th ed, p. 440, #3302 Negwer #1823 T076047 2,3-dioxanedithiol-S,S-bis(O,O-diethyl phosphorodithioate) T076049 dioxation M0308752 dioxathion, (cis)-isomer C0888390 16088-56-5 T115 Organophosphorus Compound T131 Hazardous or Poisonous Substance M0046047 M0308752 T338752 dioxathion, (cis)-isomer 1999 08 18 M0308753 dioxathion, (trans)-isomer C0888391 16270-86-3 T115 Organophosphorus Compound T131 Hazardous or Poisonous Substance M0046047 M0308753 T338753 dioxathion, (trans)-isomer 1999 08 18 M0046045 Delnav C0112807 T115 Organophosphorus Compound T131 Hazardous or Poisonous Substance M0046047 M0046045 T076048 Delnav C004765 propylene dichloride 1974 01 01 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 Russian drug; structure 41 *PROPANE (74-75) CHLORINE (74-76) HYDROCARBONS, CHLORINATED (74-82) D011407 Propane *Q000031 analogs ; derivatives D012997 Solvents Biul Eksp Biol Med 83(3):345;1977 Environ Health Perspect 30:13;1979 Gig Sanit 4:94;1977 Gig Sanit 8:50;1977 NLM TWD TWD M0045917 propylene dichloride C0072223 78-87-5 T075920 propylene dichloride Merck Index, 9th ed, p. 1017, #7643 T075919 1,2-dichloropropane C075161 early gland protein-1 1992 07 16 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; isolated from Drosophila 1 *D012471 Salivary Proteins D004330 Drosophila Mech Dev 1992 Mar;37(1-2):81-93 THA WXM WXM M0202600 early gland protein-1 C0652178 147477-75-6 T232605 early gland protein-1 T232604 egp-1 protein C004758 5-diazouracil 1969 01 01 1984 06 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN given refers to parent cpd; structure 8 AZO CPDS (69-79) DIAZONIUM COMPOUNDS (79-82) D014498 Uracil *Q000031 analogs ; derivatives J Org Chem 40(25):3717;1975 Proc Soc Exp Biol Med 139(2):592;1972 NLM GTC NLM M0045905 5-diazouracil C0049143 2435-76-9 T075908 5-diazouracil Merck Index, 9th ed, p. 395, #2967 C012881 diallylnormorphinium bromide 1976 01 01 2000 08 03 1998 1999 2000 2000A 2001 2002 RN given refers to bromide (5alpha,6alpha)-isomer 4 D009269 Nalorphine *Q000031 analogs ; derivatives Can J Physiol Pharmacol 57(1):98;1979 Eur J Pharmacol 1979;59(2-3):151 Psychopharmacologia 46(2):133;1976 NLM CCR CCR M0060238 diallylnormorphinium bromide C0057697 Morphinanium, 7,8-didehydro-4,5-epoxy-3,6-dihydroxy-17,17-di-2-propenyl-, bromide, (5alpha,6alpha)- 69576-07-4 T109 Organic Chemical 58046-45-0 (iodide(5alpha,6alpha)-isomer) M0060238 M0060237 M0060238 M0312002 T090241 diallylnormorphinium bromide M0060237 diallylnormorphine C0113547 T109 Organic Chemical M0060238 M0060237 T090240 diallylnormorphine M0312002 diallylnormorphinium bromide, iodide(5alpha,6alpha)-isomer C0889225 58046-45-0 T109 Organic Chemical M0060238 M0312002 T342002 diallylnormorphinium bromide, iodide(5alpha,6alpha)-isomer 1999 08 18 C012917 1,2-dihydroxy-1-phenylpropane 1977 01 01 2000 08 03 1998 1999 2000 2000A 2001 2002 RN given refers to cpd with unspecified isomeric designation 2 *D011409 Propylene Glycols Eur J Clin Pharmacol 9(3-4):193;1975 NLM CCR CCR M0060279 1,2-dihydroxy-1-phenylpropane C0283046 1855-09-0 T109 Organic Chemical T121 Pharmacologic Substance 1075-04-3 ((R*,S*)-isomer) 1075-05-4 ((R*,R*)-isomer) M0060279 M0312004 M0060279 M0312003 T090282 1,2-dihydroxy-1-phenylpropane T090281 1-phenoxy-2-propanol M0312004 1,2-dihydroxy-1-phenylpropane, (R*,R*)-isomer C0889227 1075-05-4 T109 Organic Chemical T121 Pharmacologic Substance M0060279 M0312004 T342004 1,2-dihydroxy-1-phenylpropane, (R*,R*)-isomer 1999 08 18 M0312003 1,2-dihydroxy-1-phenylpropane, (R*,S*)-isomer C0889226 1075-04-3 T109 Organic Chemical T121 Pharmacologic Substance M0060279 M0312003 T342003 1,2-dihydroxy-1-phenylpropane, (R*,S*)-isomer 1999 08 18 C048793 methylisopropylamiloride 1986 06 13 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 6 D000584 Amiloride *Q000031 analogs ; derivatives Am J Physiol 1986;250(5 Pt 1);C744 MEG CCR CCR M0140190 methylisopropylamiloride C0066391 1151-74-2 T170195 methylisopropylamiloride T170193 5-(methylisopropyl)amiloride T170194 5-MIPA C006513 4-amino-5-carboxymethylisoxazolid-3-one 1974 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 1 *D010080 Oxazoles Biokhimiia 38(2):365;1973 NLM TWD TWD M0049124 4-amino-5-carboxymethylisoxazolid-3-one C0048014 5-isoxazolidineacetic acid, 4-amino-3-oxo-, cis- 2644-50-0 T079127 4-amino-5-carboxymethylisoxazolid-3-one T079126 threo-alpha-cycloglutamic acid C063512 N(5)-piperazine-amiloride 1990 05 02 2001 01 30 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 D000584 Amiloride *Q000031 analogs ; derivatives J Biol Chem 1990;265(10):5341 RLS CCR CCR M0175291 N(5)-piperazine-amiloride C0640490 127628-91-5 T205296 N(5)-piperazine-amiloride T205294 5-PZA T205295 N(5)-piperazinylamiloride C004779 N,N'-dimethyl-N,N'-dinitrosoterephthalamide 1969 01 01 1982 10 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *NITROSO CPDS (73-77) *PHTHALIC ACID (69-75) *PHTHALIMIDES (75-82) AMIDES (73-75) *D009602 Nitrosamines NLM VSR NLM M0045933 N,N'-dimethyl-N,N'-dinitrosoterephthalamide C0602083 133-55-1 T075936 N,N'-dimethyl-N,N'-dinitrosoterephthalamide C063513 N(5)-piperidine-amiloride 1990 05 02 2001 01 30 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 D000584 Amiloride *Q000031 analogs ; derivatives J Biol Chem 1990;265(10):5341 RLS CCR CCR M0175294 N(5)-piperidine-amiloride C0640493 123529-15-7 T205299 N(5)-piperidine-amiloride T205297 5-PIA T205298 N(5)-piperidinylamiloride C084633 5-(N-methyl-N-propyl)amiloride 1994 01 05 2001 01 30 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 2 D000584 Amiloride *Q000031 analogs ; derivatives Mol Pharmacol 1993 Nov;44(5):1041-5 PML CCR CCR M0224816 5-(N-methyl-N-propyl)amiloride C0249553 Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(methylpropylamino)- 1151-75-3 T254821 5-(N-methyl-N-propyl)amiloride T254819 5-N-(methyl-propyl)amiloride T254820 5-N-MPA C004789 dinobuton 1969 01 01 1987 05 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 Russian drug; structure 8 *DINITROPHENOLS (75-78) CARBONATES (69-76) *D004136 Dinitrobenzenes Farmakol Toksikol 41(2):186;1978 Gig Sanit 1978(6):31;1978 Surviv Toxic Environ WA 670 S963:168;1973 Veterinariia 4:105;1977 NLM RLS NLM M0045957 dinobuton C0058307 2-sec-butyl-4,6-dinitrophenyl isopropyl carbonate 973-21-7 M0045957 M0045954 M0045957 M0045956 M0045957 M0045955 M0045957 M0045953 T075960 dinobuton Merck Index, 9th ed, p. 438, #3283 M0045954 akrex C0101984 M0045957 M0045954 T075957 akrex M0045956 izophen C0124278 M0045957 M0045956 T075959 izophen M0045955 isophen C0124146 M0045957 M0045955 T075958 isophen M0045953 Acrex C0101291 M0045957 M0045953 T075956 Acrex C004791 phepromaron 1973 01 01 1983 07 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 Russian drug 3 *COUMARINS (73-77) *D015110 4-Hydroxycoumarins Farm Zh 27(5):48;1972 Farm Zh 4:89;1978 Farmatsiia 23(5):90;1974 Kardiologiia 17(5):79;1977 NLM JSL NLM M0045961 phepromaron C0070718 15620-34-5 M0045961 M0045959 M0045961 M0045960 T075964 phepromaron M0045959 3-(alpha-phenyl-beta-propionylethyl)-4- oxycoumarin C0094993 M0045961 M0045959 T075962 3-(alpha-phenyl-beta-propionylethyl)-4- oxycoumarin M0045960 fepromaron C0117495 M0045961 M0045960 T075963 fepromaron C004794 2-4-isothiocyanophenyl-3-phenylindone 1973 01 01 1997 09 02 1997 1998 1999 2000 2001 2002 reagent for determining amino acid sequence; structure 0 THIOCYANATES (73-82) *D007192 Indenes Anal Biochem 53(2):420;1973 Dokl Bolg Akad Nauk 29(10):1483;1976 NLM MLH NLM M0045964 2-4-isothiocyanophenyl-3-phenylindone C0045785 1H-Inden-1-one, 2-(4-isothiocyanatophenyl)-3-phenyl- 17539-24-1 T075967 2-4-isothiocyanophenyl-3-phenylindone C075200 ACP-20, Tenebrio molitor 1992 07 21 2001 01 30 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; a glycine-rich cuticular protein from Coleoptera T. molitor; ACP-20 gene expression is tissue-specific ; developmentally regulated 4 *PROTEINS (92-97) *D019476 Insect Proteins Eur J Biochem 1992 Jun 15;206(3):813-9 BXB WXM WXM M0202680 ACP-20, Tenebrio molitor C0169385 147388-45-2 T232685 ACP-20, Tenebrio molitor T232684 ACP-20 gene product, T. molitor C004802 2-azidoisophthalic acid 1973 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 AZIDES (73-79) *D010795 Phthalic Acids Biochem Biophys Res Comms 52(4):1129;1973 NLM NLM M0045969 2-azidoisophthalic acid C0602087 42919-21-1 T075972 2-azidoisophthalic acid C004804 guanylyl-(3',5')-cytidine 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 11 *GUANOSINE MONOPHOSPHATE/analogs (77-88) *OLIGONUCLEOTIDES (74-76) CYTIDINE NUCLEOTIDES (74-76) CYTIDINE/*analogs (74-88) GUANINE NUCLEOTIDES (74-76) *D015226 Dinucleoside Phosphates Biochemistry 17(20):4124;1978 Biopolymers 12(12):2731;1973 Biopolymers 15(10):1951;1976 Proc Natl Acad Sci USA 70(3):849;1973 NLM NLM M0045971 guanylyl-(3',5')-cytidine C0061993 4785-04-0 T075974 guanylyl-(3',5')-cytidine C075214 TUL4 protein 1992 07 22 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from Francisella tularensis; MW 17 kDa; imvolved in a protective immunity to tularemia; amino acid has been determined 3 *D008074 Lipoproteins Infect Immun 1992 Jul;60(7):2855-62 RLS WXM WXM M0202707 TUL4 protein C0169408 130427-68-8 T232712 TUL4 protein T232711 TUL4 lipoprotein C004810 Hyparez 1973 01 01 1987 10 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains reserpine, hypothiazide, apressin, ; KCl; Russian drug 0 *D006830 Hydralazine *D006852 Hydrochlorothiazide *D011189 Potassium Chloride *D012110 Reserpine D004338 Drug Combinations Vrach Delo 1:16;1973 NLM VSR NLM M0045989 Hyparez C0602088 Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-, mixt. with 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 1(2H)-phthalazinone hydrazone and potassium chloride (KCl) 77630-46-7 T075992 Hyparez C075262 glucose regulated protein 95 1992 07 23 2001 01 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 endoplasmic reticulum glucose-regulated protein; amino acid sequence has been determined; see also record for glucose-regulated proteins 1 *D008565 Membrane Proteins D006360 Heat-Shock Proteins Postepy Biochem 1991;37(2):70-5 RLS WXM WXM M0202829 glucose regulated protein 95 C0652315 0 T232834 glucose regulated protein 95 T232833 GRP95 C075277 methoxyneurosporene dehydrogenase 1992 07 23 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; from Rhodobacter sphaeroides; involved in later stages of carotenoid biosynthesis 3 *D010088 Oxidoreductases FEMS Microbiol Lett 1992 May 15;72(1):103-8 BVL WXM WXM M0202861 methoxyneurosporene dehydrogenase C0652329 EC 1.- T232866 methoxyneurosporene dehydrogenase T232865 crtD gene product C004816 cyclohexylureide-diallylmalonic acid 1973 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *UREA (73-75) CYCLOHEXANES (73-76) UREA/*analogs (75-82) *D008314 Malonates Arch Immunol Therap Exp 20(6):939;1972 NLM VSR NLM M0046002 cyclohexylureide-diallylmalonic acid C0602089 Propanediamide, N,N'-bis((cyclohexylamino)carbonyl)-2,2-di-2-propenyl- 40556-24-9 T076005 cyclohexylureide-diallylmalonic acid C004823 ryptisin 1974 01 01 1984 09 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 active principle of soapfish toxin 0 *MARINE TOXINS (74-84) PEPTIDES (74-82) *D005397 Fish Venoms Biochem Pharmacol 22(14):1817;1973 NLM RLS NLM M0046029 ryptisin C0602090 39464-83-0 T076032 ryptisin C004827 (-)-N-allyl-3,6-beta-dihydroxymorphinan 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 metabolite of levallorphan differing by hydroxyl group in the 6 position; structure 0 *LEVALLORPHAN (73-75) D007977 Levallorphan *Q000031 analogs ; derivatives J Med Chem 16(4):352;1973 NLM NLM M0046032 (-)-N-allyl-3,6-beta-dihydroxymorphinan C0602093 40678-39-5 T076035 (-)-N-allyl-3,6-beta-dihydroxymorphinan C004828 2-(4-carboxystyryl)-5-nitro-1-vinylimidazole 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 STYRENES (73-82) *D009593 Nitroimidazoles J Med Chem 16(4):347;1973 NLM VSR NLM M0046033 2-(4-carboxystyryl)-5-nitro-1-vinylimidazole C0602094 30529-16-9 T076036 2-(4-carboxystyryl)-5-nitro-1-vinylimidazole C004830 6-chloro-16-methylene-17 alpha-hydroxy-19-nor-4,6- pregnadiene-3,20-dione 17-acetate 1974 01 01 1995 07 27 1996 1997 1998 1999 2000 2001 2002 structure 0 NORPREGNANES (74-82) PREGNENEDIONES (74-79) D002715 Chlormadinone Acetate *Q000031 analogs ; derivatives J Med Chem 16(6):649;1973 NLM MLH BVL M0046034 6-chloro-16-methylene-17 alpha-hydroxy-19-nor-4,6- pregnadiene-3,20-dione 17-acetate C0602095 27241-00-5 T076037 6-chloro-16-methylene-17 alpha-hydroxy-19-nor-4,6- pregnadiene-3,20-dione 17-acetate C004834 1,3-bis(dimethoxymethyl)phenobarbital 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *MEPHOBARBITAL (73-76) METHYL ETHERS (73-76) D008618 Mephobarbital *Q000031 analogs ; derivatives J Med Chem 16(6):599;1973 NLM NLM M0046041 1,3-bis(dimethoxymethyl)phenobarbital C0602098 42013-64-9 T076044 1,3-bis(dimethoxymethyl)phenobarbital C004837 onychofissan tincture 1973 01 01 1991 07 12 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN is for parent cpd without DMSO; combination drug containing hydroxyquinoline salicylate, undecylenic acid diethanolamide, dichlorophene ; dimethyl sulfoxide 0 *DIMETHYL SULFOXIDE (73-79) *HYDROXYQUINOLINES (75-79) *QUINOLINES (73-75) *D004003 Dichlorophen *D014476 Undecylenic Acids *D015125 Oxyquinoline D004338 Drug Combinations Mykosen 16(4):137;1973 NLM IDX TPW M0046043 onychofissan tincture C0602099 2-hydroxybenzoic acid compd. with 8-quinolinol mixt. with N,N-bis(2-hydroxyethyl)-10-undecenamide ; 2,2'- methylenebis(4-chlorophenol) 64827-89-0 T076046 onychofissan tincture UD 23:39m C004839 dioxybenzone 1969 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 PHENOLS (73-76) *D001577 Benzophenones Contact Dermititis 3(3):172;1977 NLM NLM M0046048 dioxybenzone C0058344 2,2'-dihydroxy-4-methoxybenzophenone 131-53-3 T076051 dioxybenzone Negwer 2096 C004857 diphemethoxidine 1970 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D010880 Piperidines NLM NLM M0046067 diphemethoxidine C0602101 2-(diphenylmethyl)-1-piperidineethanol 13862-07-2 T076070 diphemethoxidine C004940 glucuronolactone 1969 01 01 2000 06 21 1998 1999 2000 2000A 2001 2002 RN given refers to (D)-isomer 15 LACTONES (69-76) *D005965 Glucuronates Acta Pharmacol Toxicol 41:263;1977 NLM CCR CCR M0046169 glucuronolactone C0061446 32449-92-6 T118 Carbohydrate T121 Pharmacologic Substance 23784-13-6 (6-(14)C-labeled cpd) M0046169 M0308807 T076172 glucuronolactone Merck Index, 9th ed, p. 578, #4300 T076171 glucuronic acid, gamma-lactone M0308807 glucuronolactone, 6-(14)C-labeled C0888416 23784-13-6 T118 Carbohydrate T130 Indicator, Reagent, or Diagnostic Aid M0046169 M0308807 T338807 glucuronolactone, 6-(14)C-labeled 1999 08 18 C004888 subathizone 1972 01 01 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *THIOSEMICARBAZONES (72-82) *D013450 Sulfones NLM TWD TWD M0046101 subathizone C0602109 121-55-1 T076104 subathizone Merck Index, 9th ed, p.1147, #8659 T076103 p-ethylsulfonylbenzaldehyde thiosemicarbazone C004867 eburicoic acid 1970 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *STEROLS (70-75) CARBOXYLIC ACIDS (72-76) D007810 Lanosterol *Q000031 analogs ; derivatives NLM NLM M0046082 eburicoic acid C0602102 3 beta-hydroxy-24-methylene-8-lanostene-21-oic acid 560-66-7 T076085 eburicoic acid C001460 iodopropamide 1972 01 01 2000 06 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 RN given refers to parent cpd 0 IODOBENZENES (73-76) *D013453 Sulfonylurea Compounds J Nucl Med 13(3):215;1972 NLM CCR CCR M0041673 iodopropamide C0601102 4-iodo-N-((propylamino)carbonyl)benzenesulfonamide 30961-44-5 T109 Organic Chemical 33404-11-4 (125I-labeled cpd) M0041673 M0307664 T071676 iodopropamide T071675 1-(p-iodobenzenesulfonyl)-3-(n-propyl)urea M0307664 iodapropamide, 125I-labeled C0888070 33404-11-4 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0041673 M0307664 T337664 iodapropamide, 125I-labeled 1999 08 18 C075437 INO2 protein 1992 08 02 2001 01 30 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a helix-loop-helix protein required for activation of phospholipid synthesis; 304 aa residues, MW 34.2 kDa; aa sequence has been determined 23 *D004268 DNA-Binding Proteins *D005656 Fungal Proteins D012441 Saccharomyces cerevisiae D014157 Transcription Factors D018257 Helix-Loop-Helix Motifs Nucleic Acids Res Jun 25;20(12):3253 RLS WXM WXM M0203282 INO2 protein C0169863 148093-80-5 T233287 INO2 protein T233286 INO2 gene product C004883 N-ethylisatin-beta-thiosemicarbazone 1970 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *INDOLES (70-76) *THIOSEMICARBAZONES (70-82) D007510 Isatin *Q000031 analogs ; derivatives NLM RLS NLM M0046097 N-ethylisatin-beta-thiosemicarbazone C0602105 1-ethylindole-2,3-dione-3-(thiosemicarbazone) 607-05-6 T076100 N-ethylisatin-beta-thiosemicarbazone C075448 bone-inducing protein, osteosarcoma 1992 08 02 2001 01 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 9 amino acid N-terminal sequence given in first source; isolated from a murine osteosarcoma; induces bone formation with active haematopoiesis; N terminal sequence and total amino acid composition closely match ribosomal protein L32 1 *D009363 Neoplasm Proteins D010012 Osteogenesis Biochem J 1992 Jun 15;284(Pt 3):847-54 THA WXM WXM M0203301 bone-inducing protein, osteosarcoma C0652519 0 T233306 bone-inducing protein, osteosarcoma T233305 osteosarcoma BIP C075458 225 kDa protein, Babesia bovis 1992 08 03 2001 01 30 1998 1999 2000 2001 2001A 2002 located on the cytoplasmic side of the erythrocyte; has sequence similarity with glycogen phosphorylase; aa sequence has been determined 1 *D015800 Protozoan Proteins D000953 Antigens, Protozoan D006005 Phosphorylases Mol Biochem Parasitol 1992 Jun;52(2):263-9 BXB WXM WXM M0203318 225 kDa protein, Babesia bovis C0652530 0 T233323 225 kDa protein, Babesia bovis T233322 B. bovis 225 kDa protein C075467 RAD16 protein 1992 08 03 2001 01 30 1998 1999 2000 2001 2001A 2002 component of NEF4, also known as nucleotide excision repair factor 4; a yeast excision repair gene involved in excision repair of DNA; aa sequence known 28 *D005656 Fungal Proteins D000251 Adenosinetriphosphatase D004260 DNA Repair D012441 Saccharomyces cerevisiae Yeast 1992 May;8(5):385-95 RLS WXM WXM M0203335 RAD16 protein C0169921 0 T233340 RAD16 protein T233339 RAD16 gene product C075489 serine proteinase inhibitor, tobacco 1992 08 04 2001 01 30 1996 1997 1998 1999 2000 2001 2001A 2002 highly active against serine endoproteinases from fungi and bacteria; poor inhibitor of serine proteinases from animals; amino terminal amino acid sequence given in first source; belongs to the potato inhibitor I family 3 *D010940 Plant Proteins Mol Plant Microbe Interact 1990 Sep-Oct;3(5):327-33 BVL WXM WXM M0203383 serine proteinase inhibitor, tobacco C0169971 0 T233388 serine proteinase inhibitor, tobacco T233387 tobacco inhibitor I C035179 iodotamoxifen 1982 09 08 2000 06 22 1998 1999 2000 2000A 2001 2002 RN given refers to unlabeled cpd(Z)-isomer; structure given in first source 5 D013629 Tamoxifen *Q000031 analogs ; derivatives Int J Nucl Med Biol 1982;9(2):105 VSR CCR CCR M0107955 iodotamoxifen C0063798 Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)-2-iodophenoxy)-N,N-dimethyl-, (Z)- 76070-10-5 T109 Organic Chemical T121 Pharmacologic Substance 76060-32-7 (125I-labeled cpd(Z)-isomer) M0107955 M0320299 T137959 iodotamoxifen M0320299 iodotamoxifen, 125I-labeled, (Z)-isomer C0892295 76060-32-7 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0107955 M0320299 T350299 iodotamoxifen, 125I-labeled, (Z)-isomer 1999 08 18 C004923 muscazone 1973 01 01 1982 07 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 from Amanita muscaria; structure 0 AMMONIUM COMPOUNDS (73-82) *D010080 Oxazoles D014118 Toxins N Engl J Med 289(3):379;1973 NLM VSR NLM M0046139 muscazone C0066958 2255-39-2 T076142 muscazone C009830 pirlindole 1975 01 01 2000 06 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 RN given refers to parent cpd; synonym pyrazidol refers to mono-HCl; structure in Negwer, 5th ed, #2812 84 *INDOLES (75-80) *PYRAZINES (75-80) *D002227 Carbazoles Farmakol Toksikol 38(1):5;1975 Farmakol Toksikol 39(4):397;1976 Farmakol Toksikol 39(5):531;1975 Farmakol Toksikol 39(5):607;1977 Farmakol Toksikol 40(4):442;1977 Farmakol Toksikol 41(1):36;1978 Farmakol Toksikol 41(4):385;1978 Farmakol Toksikol 6:682;1976 Zh Neuropatol Psikhiatr 75(6):906;1975 Zh Neuropatol Psikhiatr 77(2):266;1977 NLM CCR CCR M0054889 pirlindole C0071143 1H-Pyrazino(3,2,1-jk)carbazole, 2,3,3a,4,5,6-hexahydro-8-methyl-, monohydrochloride 60762-57-4 T109 Organic Chemical T121 Pharmacologic Substance D000928 Antidepressive Agents D000970 Antineoplastic Agents D008996 Monoamine Oxidase Inhibitors 16154-78-2 (HCl) 32957-93-0 (unspecified HCl) M0054889 M0310944 T084892 pirlindole Negwer, 5th ed, #2812 T084888 1,10-trimethylene-8-methyl-1,2,3,4-tetrahydropyrazino(1,2-a)indole T084889 pirlindol T084891 pyrlindole M0310944 pirlindole hydrochloride C0139426 16154-78-2 T109 Organic Chemical T121 Pharmacologic Substance M0054889 M0310944 T340944 pirlindole hydrochloride 1999 08 18 T084890 pyrazidol C081460 RU 50331 1993 06 29 2001 07 23 1996 1997 1998 1999 2000 2001 2001A 2002 progesterone antagonist 1 *D005663 Furans *D006067 Gonanes J Steroid Biochem Mol Biol 1993 Apr;45(4):205-15 PML TWD TWD M0217283 RU 50331 C0659277 RU 50331 136960-03-7 M0217283 M0217277 M0217283 M0217278 T247288 RU 50331 T247285 RU-50331 T247287 RU50,331 M0217277 4',5'-dihydro-11 beta-(4-dimethylaminophenyl)-13-methyl-spiro(gona-4,9-dien-17,2'-(3H)-furan)-3-one C0659271 M0217283 M0217277 T247282 4',5'-dihydro-11 beta-(4-dimethylaminophenyl)-13-methyl-spiro(gona-4,9-dien-17,2'-(3H)-furan)-3-one M0217278 RU 331 C0659275 M0217283 M0217278 T247283 RU 331 T247284 RU-331 T247286 RU331 C004932 diloxanide furoate 1970 01 01 2001 07 23 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 34 ACETANILIDES (70-82) *D005663 Furans Dermatologica 151(4):253;1975 Ethiop Med J 15(3):101;1977 J Assoc Physicians India 24(2):84;1976 Med Welt 29(24):1024;1978 NLM TWD TWD M0046158 diloxanide furoate C0058181 3736-81-0 D000563 Amebicides M0046158 M0046155 M0046158 M0046157 T076161 diloxanide furoate Merck Index, 9th ed, p. 425, in #3186 Negwer #2074 T076157 2,2-dichloro-4'-hydroxy-N-methylacetanilide 2-furoate T076159 entamide furoate M0046155 diloxanide C0206816 M0046158 M0046155 T076158 diloxanide M0046157 Furamide C0678153 M0046158 M0046157 T076160 Furamide C002607 IPCM 1973 01 01 2000 06 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 radio-iodinated chloromerodrin analog used in kidney scanning; RN given refers to parent cpd; structure 0 *IODOBENZENES (73-76) *UREA (73-75) MERCURY (73-75) D002717 Chlormerodrin *Q000031 analogs ; derivatives Nucl Med 11(4):407;1972 NLM CCR CCR M0043279 IPCM C0601531 chloro(3-((((4-iodophenyl)amino)carbonyl)amino)-2-methoxypropyl)mercury 39877-25-3 T109 Organic Chemical 42436-29-3 (125I-labeled cpd) 42436-32-8 (203Hg-labeled cpd) M0043279 M0308006 M0043279 M0308005 T073282 IPCM T073281 1-(4-iodophenyl)-3-((3-chloromercuri)-2-methoxypropyl)urea M0308006 IPCM, 203Hg-labeled C0888123 42436-32-8 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0043279 M0308006 T338006 IPCM, 203Hg-labeled 1999 08 18 M0308005 IPCM, 125I-labeled C0888122 42436-29-3 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0043279 M0308005 T338005 IPCM, 125I-labeled 1999 08 18 C071469 MK 287 1991 12 04 2001 07 23 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to the trans-(-)-isomer L-680573; L-680574 is an optical enantiomer; L-668750 is the racemic mixture; structure given in first source 3 *D005663 Furans Biol Mass Spectrom 1991;20(7):408 TPW TWD TWD M0194112 MK 287 C0128625 135947-75-0 143445-03-8 ((trans-(+-))-isomer) 143490-81-7 ((2R-trans)-isomer) M0194112 M0325480 M0194112 M0325479 M0194112 M0194102 M0194112 M0194104 M0194112 M0194106 M0194112 M0194107 T224117 MK 287 T224116 MK-287 M0325480 MK 287, (2R-trans)-isomer C0958775 143490-81-7 M0194112 M0325480 T355480 MK 287, (2R-trans)-isomer 1999 08 18 M0325479 MK 287, (trans-(+-))-isomer C0958774 143445-03-8 M0194112 M0325479 T355479 MK 287, (trans-(+-))-isomer 1999 08 18 M0194102 2-((3-methoxy-5-(2-hydroxyethylsulfonyl)-4-propoxyl)-phenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran C0246609 M0194112 M0194102 T224107 2-((3-methoxy-5-(2-hydroxyethylsulfonyl)-4-propoxyl)-phenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran T224108 2-(3-methoxy-4-propoxy-5-(ethanolsulphonyl)phenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran M0194104 L 668,750 C0173650 M0194112 M0194104 T224109 L 668,750 T224110 L 668750 T224113 L-668750 M0194106 L 680573 C0246610 M0194112 M0194106 T224111 L 680573 T224114 L-680573 M0194107 L 680574 C0246611 M0194112 M0194107 T224112 L 680574 T224115 L-680574 C004952 prozapine 1970 01 01 1983 07 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN given refers to parent cpd; structure 1 BENZENE DERIVATIVES (72-75) BENZHYDRYL COMPOUNDS (75-82) *D001381 Azepines J Pharm Sci 64(11):1866;1975 Med Chir Dig 7(5):437;1978 Minerva Gastroenterol 18(1):27;1972 Minerva Gastroenterol 18(1):35;1972 NLM JSL NLM M0046189 prozapine C0072512 3426-08-2 13657-24-4 (HCl) 33001-58-0 (maleate) M0046189 M0046188 M0046189 M0046187 M0046189 M0308815 M0046189 M0308816 T076192 prozapine Merck 9th ed, p. 1024, #7692 M0046188 hexadiphene C0121609 M0046189 M0046188 T076191 hexadiphene M0046187 1-(3,3-diphenylpropyl)hexamethyleneimine C0088738 M0046189 M0046187 T076190 1-(3,3-diphenylpropyl)hexamethyleneimine M0308815 HCl of prozapine C0771434 13657-24-4 M0046189 M0308815 T338815 HCl of prozapine 1999 08 18 M0308816 maleate of prozapine C0894680 33001-58-0 M0046189 M0308816 T338816 maleate of prozapine 1999 08 18 C004974 5-chloro-1,3-dihydro-2H-imidazo(4,5-b)pyrazin-2-one 1973 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 IMIDAZOLES (73-82) *D011719 Pyrazines J Med Chem 1973;16(5):537 NLM VSR NLM M0046220 5-chloro-1,3-dihydro-2H-imidazo(4,5-b)pyrazin-2-one C0602125 33386-23-1 T076223 5-chloro-1,3-dihydro-2H-imidazo(4,5-b)pyrazin-2-one C004975 alpha-(2-piperidyl)-4-quinolinemethanol 1973 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ALCOHOL, METHYL (73-76) PIPERIDINES (73-82) *D011804 Quinolines J Med Chem 16(5):528;1973 NLM VSR NLM M0046221 alpha-(2-piperidyl)-4-quinolinemethanol C0602126 0 T076224 alpha-(2-piperidyl)-4-quinolinemethanol C004976 delta-N-hydroxyornithine 1973 01 01 1995 09 21 1995 1996 1997 1998 1999 2000 2001 2002 constituent of ferrichromes; structure 2 *HYDROXYLAMINES (73-76) *ORNITHINE (73-75) D009952 Ornithine *Q000031 analogs ; derivatives D009955 Ornithine Decarboxylase Q000037 antagonists ; inhibitors Can J Biochem 51(6):754;1973 NLM BVL NLM M0046224 delta-N-hydroxyornithine C0057349 N(5)-hydroxy-L-ornithine 35187-58-7 M0046224 M0046222 M0046224 M0046223 T076227 delta-N-hydroxyornithine M0046222 DL-2-amino-5-hydroxylaminopentanoic acid C0114440 M0046224 M0046222 T076225 DL-2-amino-5-hydroxylaminopentanoic acid M0046223 omega-N-hydroxyornithine C0162942 M0046224 M0046223 T076226 omega-N-hydroxyornithine C084077 galgravin 1993 12 07 2001 07 23 1995 1996 1997 1998 1999 2000 2001 2001A 2002 an anti-PAF constituent from the stems of Piper futokadsura, the Chinese drug haifengteng; structures of the isomers galgravin, galbelgin (10569-12-7) and veraguensin (19950-55-1) given in first source; RN given refers to galgravin, the (2alpha,3beta,4beta,5alpha)-isomer 2 *D005663 Furans D004365 Drugs, Chinese Herbal Chung Kuo Chung Yao Tsa Chih 1993 May;18(5):292-4,318 PML TWD TWD M0223512 galgravin C0527913 528-63-2 103774-96-5 ((2alpha,3alpha,4alpha,5beta)-(+-)-isomer) 104112-96-1 ((2alpha,3alpha,4alpha,5beta)-isomer) 104112-97-2 ((2alpha,3alpha,4beta,5alpha)-isomer) 104112-98-3 ((2alpha,3beta,4alpha,5beta)-isomer) 10569-12-7 ((2S-(2alpha,3beta,4alpha,5beta))-isomer) 19950-55-1 ((2R-(2alpha,3alpha,4beta,5alpha))-isomer) 27686-82-4 ((2alpha,3alpha,4alpha,5alpha)-isomer) 83377-13-3 ((2alpha,3alpha,4beta,5beta)-(+)-isomer) M0223512 M0326350 M0223512 M0326344 M0223512 M0326345 M0223512 M0326346 M0223512 M0326351 M0223512 M0326347 M0223512 M0326349 M0223512 M0326348 T253517 galgravin T253515 galbelgin T253516 veraguensin M0326350 galgravin, (2alpha,3alpha,4alpha,5alpha)-isomer C0959356 27686-82-4 M0223512 M0326350 T356350 galgravin, (2alpha,3alpha,4alpha,5alpha)-isomer 1999 08 18 M0326344 galgravin, (2alpha,3alpha,4alpha,5beta)-(+-)-isomer C0959350 103774-96-5 M0223512 M0326344 T356344 galgravin, (2alpha,3alpha,4alpha,5beta)-(+-)-isomer 1999 08 18 M0326345 galgravin, (2alpha,3alpha,4alpha,5beta)-isomer C0959351 104112-96-1 M0223512 M0326345 T356345 galgravin, (2alpha,3alpha,4alpha,5beta)-isomer 1999 08 18 M0326346 galgravin, (2alpha,3alpha,4beta,5alpha)-isomer C0959352 104112-97-2 M0223512 M0326346 T356346 galgravin, (2alpha,3alpha,4beta,5alpha)-isomer 1999 08 18 M0326351 galgravin, (2alpha,3alpha,4beta,5beta)-(+)-isomer C0959357 83377-13-3 M0223512 M0326351 T356351 galgravin, (2alpha,3alpha,4beta,5beta)-(+)-isomer 1999 08 18 M0326347 galgravin, (2alpha,3beta,4alpha,5beta)-isomer C0959353 104112-98-3 M0223512 M0326347 T356347 galgravin, (2alpha,3beta,4alpha,5beta)-isomer 1999 08 18 M0326349 galgravin, (2R-(2alpha,3alpha,4beta,5alpha))-isomer C0959355 19950-55-1 M0223512 M0326349 T356349 galgravin, (2R-(2alpha,3alpha,4beta,5alpha))-isomer 1999 08 18 M0326348 galgravin, (2S-(2alpha,3beta,4alpha,5beta))-isomer C0959354 10569-12-7 M0223512 M0326348 T356348 galgravin, (2S-(2alpha,3beta,4alpha,5beta))-isomer 1999 08 18 C004996 fenozolone 1973 01 01 1994 06 22 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 *PEMOLINE CPDS (73-79) D010389 Pemoline *Q000031 analogs ; derivatives CR Acad Sci Paris (D) 287(1):53;1978 Encephale 2(1):55;1976 NLM MLH TPW M0046257 fenozolone C0060187 2-ethylamino-5-phenyl-2-oxazolin-4-one 15302-16-6 T076260 fenozolone Negwer #1387 C004997 fenpentadiol 1973 01 01 1982 02 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 CHLOROBENZENES (73-82) *D006018 Glycols NLM NBM NLM M0046258 fenpentadiol C0060188 2-(4-chlorophenyl)-4-methyl-2,4-pentanediol 15687-18-0 T076261 fenpentadiol Negwer, 5th ed, #1987 C005109 methanesulfonyl fluoride 1973 01 01 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 23 FLUORINE (73-76) *D013450 Sulfones Am Ind Hyg Assoc J 1979;40(11):986 Anal Biochem 72:447;1976 Biochemistry 17(13):2645;1978 Dev Biol 69(1):46;1979 Gen Pharmacol 8(5-6):331;1977 J Physiol 270:133;1977 Neuropharmacol 14(11):791;1975 NLM TWD TWD M0046448 methanesulfonyl fluoride C0066089 558-25-8 D002800 Cholinesterase Inhibitors T076451 methanesulfonyl fluoride T076450 methylsulfonylfluoride C005057 isocyanic acid 1969 01 01 2000 12 07 1998 1999 2000 2001 2001A 2002 structure 63 *D003485 Cyanates NLM CCR CCR M0046355 isocyanic acid C0063959 75-13-8 T197 Inorganic Chemical M0046355 M0046354 T076358 isocyanic acid Merck Index, 8th ed, p. 583 M0046354 hydrogen isocyanide C0602136 T197 Inorganic Chemical M0046355 M0046354 T076357 hydrogen isocyanide C025024 acetylphenyl-alanyl-lysine chloromethyl ketone 1980 06 30 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 noncompetitive inhibitor of trypsin(K(I)=.0059 M) 1 *D000590 Amino Acid Chloromethyl Ketones Experientia 1980;36(4):397 NBM CCR CCR M0083906 acetylphenyl-alanyl-lysine chloromethyl ketone C0610368 Benzenepropanamide, alpha-(acetylamino)-N-(5-amino-1-(chloroacetyl)pentyl)-, (S-(R*,R*))- 76157-63-6 T113909 acetylphenyl-alanyl-lysine chloromethyl ketone T113907 Ac-Phe-Lys-CH2Cl T113908 acetyl-Phe-Lys-chloromethyl ketone C028781 aminopropylon 1981 04 08 2000 12 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to cpd without isomeric designation; structure in Merck Index, 9th ed, #483 2 ANTIPYRINE/*analogs (81-86) D000632 Aminopyrine *Q000031 analogs ; derivatives J Immunol Methods 1980;35(1-2):147 RLS WXM WXM M0092287 aminopropylon C0051671 3690-04-8 T109 Organic Chemical T121 Pharmacologic Substance 62951-82-0 ((+-)-isomer) M0092287 M0317902 T122290 aminopropylon Merck Index, 9th ed, #483 Negwer, 5th ed, #3150 T122289 aminopropyron T122288 aminopropylone T122287 4-(2-(dimethylamino)propionamide)antipyrine M0317902 aminopropylon, (+-)-isomer C0954572 62951-82-0 T109 Organic Chemical T121 Pharmacologic Substance M0092287 M0317902 T347902 aminopropylon, (+-)-isomer 1999 08 18 C028558 isoleucyl-glutamyl-glycyl-arginine chloromethyl ketone 1981 03 25 2001 01 30 1998 1999 2000 2001 2001A 2002 specific covalent factor Xa inhibitor 1 *D000590 Amino Acid Chloromethyl Ketones D015951 Factor Xa Q000037 antagonists ; inhibitors J Biol Chem 1981;256(4):1625 MEG CCR CCR M0091786 isoleucyl-glutamyl-glycyl-arginine chloromethyl ketone C0612335 0 T121789 isoleucyl-glutamyl-glycyl-arginine chloromethyl ketone T121787 IGGACMK T121788 Ile-Glu-Gly-Arg-chloromethyl ketone C005017 fluperolone acetate 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PREGNADIENETRIOLS (74-75) STEROIDS, FLUORINATED (74-75) D005477 Fluprednisolone *Q000031 analogs ; derivatives NLM NLM M0046300 fluperolone acetate C0602134 9-fluoro-11 beta,17 alpha-hydroxy-17-lactoylandrosta-1,4-diene 17 beta-acetate 2119-75-7 T076303 fluperolone acetate Merck Index, 9th ed, p. 541, #4072 Negwer #4309 C067184 4-(cyclohexylmethylamino)-1,2-naphthoquinone 1991 03 09 2001 04 12 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 *D009285 Naphthoquinones Pharm Res 1990;7(10):1071 RLS CCR CCR M0184237 4-(cyclohexylmethylamino)-1,2-naphthoquinone C0644103 25107-73-7 M0184237 M0184239 T214242 4-(cyclohexylmethylamino)-1,2-naphthoquinone M0184239 CGS 19213 C0644104 M0184237 M0184239 T214244 CGS 19213 T214243 CGS-19213 C029959 benzyloxycarbonylalanine chloromethyl ketone 1981 06 24 2001 01 30 1998 1999 2000 2001 2001A 2002 inhibits the processing of prolipoprotein of E coli; RN given refers to (S)-(-)-isomer 1 *D000590 Amino Acid Chloromethyl Ketones J Biol Chem 1981;256(10):4712 RLS CCR CCR M0095153 benzyloxycarbonylalanine chloromethyl ketone C0613191 carbamic acid, (3-chloro-1-methyl-2-oxopropyl)-, phenylmethyl ester, (S)- 41036-43-5 T125156 benzyloxycarbonylalanine chloromethyl ketone T125155 benzyloxycarbonyl-Ala-chloromethyl ketone T125154 Z-Ala-chloromethyl ketone C005035 hexametaphosphate 1969 01 01 1998 01 07 1998 1999 2000 2001 2002 8 *CYCLIC P-OXIDES (69-75) *PYROPHOSPHATES (69-75) *D010710 Phosphates J Dent Res 1980;59(1):77 NLM PML NLM M0046316 hexametaphosphate C0062636 13478-98-3 T076319 hexametaphosphate C071895 A 80915A 1992 01 06 2001 04 12 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 antibiotic complex from Streptomyces aculeolatus 4 *D009285 Naphthoquinones Biochem Pharmacol 1991;42(10):2019-26 BXB CCR CCR M0195025 A 80915A C0100810 2H-Naphtho(2,3-b)pyran-5,10-dione, 3,4a-dichloro-10a-((3-chloro-2,2-dimethyl-6-methylenecyclohexyl)methyl)-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2,7-trimethyl- 127875-60-9 M0195025 M0195023 T225030 A 80915A T225029 A80915A M0195023 3,4a-dichloro-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2,7-trimethyl-10a-((2,2-dimethyl-3-chloro-6-methylenecyclohexyl)methyl)-2H-naphtho(2,3,b)pryan-5,10-dione C0094605 M0195025 M0195023 T225028 3,4a-dichloro-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2,7-trimethyl-10a-((2,2-dimethyl-3-chloro-6-methylenecyclohexyl)methyl)-2H-naphtho(2,3,b)pryan-5,10-dione C005041 hydrargaphen 1969 01 01 1983 06 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN given refers to parent cpd; structure 1 *MERCURY (69-77) *ORGANOMETALLIC CPDS (69-76) NAPHTHALENESULFONATES (74-82) *D010663 Phenylmercury Compounds NLM JSL NLM M0046323 hydrargaphen C0063061 3,3'-bis(naphthalene-2-sulfonic acid) phenyl mercury salt 14235-86-0 T076326 hydrargaphen Merck Index, 9th ed, p. 626, #4649 Negwer #3711 C081668 2,4-dimethoxybenzhydrylamine 1993 07 12 2000 12 15 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2001B 2002 1 *D001559 Benzhydryl Compounds D012116 Resins, Plant J Med Chem 1993 Jun 11;36(12):1681-8 THA TWD TWD M0217769 2,4-dimethoxybenzhydrylamine C0659465 106864-38-4 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T247774 2,4-dimethoxybenzhydrylamine T247773 2,4-DMBHA C023845 N-ethyl-N-hydroxyethylnitrosamine 1980 05 06 2000 12 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 61 D004052 Diethylnitrosamine *Q000031 analogs ; derivatives Gan 1979;70(6):817 RLS CCR CCR M0081530 N-ethyl-N-hydroxyethylnitrosamine C0067957 2-(ethylnitrosamino)ethanol 13147-25-6 T109 Organic Chemical D002273 Carcinogens T111533 N-ethyl-N-hydroxyethylnitrosamine T111531 N-ethyl-N-(2-hydroxyethyl)nitrosamine T111532 N-nitrosoethyl-2-hydroxyethylamine C014129 N-nitrosodiethanolamine 1977 01 01 2000 12 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 100 *NITROSAMINES (77-78) D004052 Diethylnitrosamine *Q000031 analogs ; derivatives Arch Int Physiol Biochim 1979;87(4):813 Cancer Lett 2(3):125;1977 Cancer Lett 4:207;1978 NLM CCR CCR M0062425 N-nitrosodiethanolamine C0068206 1116-54-7 T109 Organic Chemical D002273 Carcinogens T092428 N-nitrosodiethanolamine T092427 diethanolnitrosamine C080506 N-(2-(bis(4-fluorophenyl)methylthio)ethyl)-N-methyl-N-(2-phenyl)ethylamine 1993 04 29 2001 02 02 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source; calmodulin antagonist 1 *D001559 Benzhydryl Compounds D003543 Cysteamine *Q000031 analogs ; derivatives D008024 Ligands Methods Find Exp Clin Pharmacol 1992 Dec;14(10):759-65 THA TWD TWD M0215094 N-(2-(bis(4-fluorophenyl)methylthio)ethyl)-N-methyl-N-(2-phenyl)ethylamine C0658205 Benzeneethanamine, N-(2-((bis(4-fluorophenyl)methyl)thio)ethyl)-N-methyl-3-(trifluoromethyl)- 146931-13-7 T109 Organic Chemical T121 Pharmacologic Substance M0215094 M0215096 T245099 N-(2-(bis(4-fluorophenyl)methylthio)ethyl)-N-methyl-N-(2-phenyl)ethylamine M0215096 VUF 4576 C0658206 T109 Organic Chemical T121 Pharmacologic Substance M0215094 M0215096 T245101 VUF 4576 UD 44:195j T245100 VUF-4576 C005065 Bio-Strath 1973 01 01 1980 12 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 yeast preparation 1 *D015002 Yeast, Dried Radiol Clin Biol 42(3):222;1973 NLM BEJ NLM M0046367 Bio-Strath C0602140 0 T076370 Bio-Strath C005067 2-deoxy-6-phosphogluconate 1973 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 DEOXY SUGARS (73-76) HEXOSEPHOSPHATES (73-82) *D005942 Gluconates J Biol Chem 248(14):4920;1973 NLM VSR NLM M0046369 2-deoxy-6-phosphogluconate C0046062 D-arabino-Hexonic acid, 2-deoxy-, 6-(dihydrogen phosphate) 3006-63-1 T076372 2-deoxy-6-phosphogluconate C031135 succinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone 1981 08 20 2001 01 30 1995 1996 1997 1998 1999 2000 2001 2001A 2002 3 *D000590 Amino Acid Chloromethyl Ketones D010196 Pancreatic Elastase Q000037 antagonists ; inhibitors Am Rev Respir Dis 1981;124(1):56 RLS CCR CCR M0098043 succinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone C0075441 L-Prolinamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-N-(3-chloro-1-(1-methylethyl)-2-oxopropyl)-, (S)- 65144-33-4 T128047 succinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone T128045 SAAPVC T128046 Suc-Ala-Ala-Pro-Val-chloromethyl ketone C006772 2,7,12,17-tetraethyl-3,8,13,18-tetramethyl-21H,23H-porphine rhodium complex 1974 01 01 2001 01 30 1998 1999 2000 2001 2001A 2002 luminescing porphyrin; RN given refers to chloride dihydrate 0 *D009942 Organometallic Compounds *D011166 Porphyrins D012238 Rhodium J Am Chem Soc 95(15):4822;1973 NLM TWD TWD M0049515 2,7,12,17-tetraethyl-3,8,13,18-tetramethyl-21H,23H-porphine rhodium complex C0602850 Rhodium(1+), bis(N-methylmethanamine)(2,7,12,17-tetraethyl-3,8,13,18-tetramethyl-21H,23H-porphinato(2-)-N(21),N(22),N(23),N(24))-, chloride, dihydrate, (OC-6-12)- 50773-64-3 T079518 2,7,12,17-tetraethyl-3,8,13,18-tetramethyl-21H,23H-porphine rhodium complex T079517 bis(dimethylamine)etio(I)porphinatorhodium(III) chloride dihydrate C005074 12 alpha-etiojervane 1973 01 01 1990 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 this ; 7-acetylthio-17-subst-derivs are potent aldosterone antagonists; structure 0 *INDENES (73-75) *NAPHTHALENES (73-78) INDANS (73-82) *D013764 Tetrahydronaphthalenes J Med Chem 16(5):568;1973 NLM TBT NLM M0046388 12 alpha-etiojervane C0602141 0 T076391 12 alpha-etiojervane C005076 hexanoylcholine 1973 01 01 1984 12 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN given refers to parent cpd 1 *CHOLINE (73-75) CAPROATES (73-76) D002794 Choline *Q000031 analogs ; derivatives Jpn J Pharmacol 22(6):777;1973 NLM MGR NLM M0046392 hexanoylcholine C0062657 N,N,N-trimethyl-2-((1-oxohexyl)oxy)ethanaminium 16639-00-2 18885-38-6 (iodide) M0046392 M0046391 M0046392 M0308897 T076395 hexanoylcholine M0046391 caprylylcholine C0108302 M0046392 M0046391 T076394 caprylylcholine M0308897 iodide of hexanoylcholine C0894709 18885-38-6 M0046392 M0308897 T338897 iodide of hexanoylcholine 1999 08 18 C088404 2-methoxymethyl-1,4-naphthoquinone 1994 08 15 2001 04 12 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a bioreductive alkylating agent; structure given in first source; name given in first source (2-methylmethoxy....) is incorrect 1 *D009285 Naphthoquinones Biochem J 1994 Jul 1;301(Pt 1):21-30 PML CCR CCR M0233995 2-methoxymethyl-1,4-naphthoquinone C0257182 39510-88-8 T264000 2-methoxymethyl-1,4-naphthoquinone T263999 2-methylmethoxy-1,4-naphthoquinone T263998 2-MOM-1,4-naphthoquinone C100451 NSC 117027 1996 08 22 2001 04 12 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 *D009285 Naphthoquinones J Med Chem 1996 Jun 21;39(13):2472-81 PML CCR CCR M0263717 NSC 117027 C0391067 0 M0263717 M0263715 T293722 NSC 117027 T293721 NSC-117027 M0263715 1,4-bis((di-(3-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl))methyl)benzene C0391066 M0263717 M0263715 T293720 1,4-bis((di-(3-hydroxy-1,4-dioxo-1,4-dihydronaphthalen-2-yl))methyl)benzene C071933 RBP-Jkappa protein 1992 01 10 2000 06 24 1998 1999 2000 2000A 2000B 2001 2002 60-kDa mammalian protein that specifically binds to immunoglobulin Jkappa recombination signal sequence; interacts with EBNA2; amino acid sequence given in first source; do not confuse with centromere-binding protein CBF-1 or with cmp-binding factor 1 or with proto-oncogene protein c-qin 106 *D004268 DNA-Binding Proteins J Biol Chem 1991;266(34):23334 BXB THA THA M0195115 RBP-Jkappa protein C0139989 143777-43-9 D012097 Repressor Proteins M0195115 M0195110 M0195115 M0195111 M0195115 M0195112 M0195115 M0195113 M0195115 M0195114 T225120 RBP-Jkappa protein T417712 Rbpsuh gene product 2000 06 24 M0195110 C-promotor-binding factor 1 C0287454 M0195115 M0195110 T225115 C-promotor-binding factor 1 M0195111 CBF1 (mammalian) C0287455 M0195115 M0195111 T225116 CBF1 (mammalian) M0195112 CBF1-RBPJk C0287456 M0195115 M0195112 T225117 CBF1-RBPJk M0195113 J kappa protein C0246647 M0195115 M0195113 T225118 J kappa protein M0195114 KBF2 protein C0379083 M0195115 M0195114 T225119 KBF2 protein C005138 atromepine 1970 01 01 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *TROPANES (70-75) PHENYLACETATES (74-75) *D001286 Atropine Derivatives NLM TWD TWD M0046464 atromepine C0602147 3 alpha-tropanyl-2-methyl-2-phenylhydracrylate 428-07-9 T076467 atromepine T076466 levomepate C033481 N-formylnorleucyl-leucyl-phenylalanine chloromethyl ketone 1982 03 05 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 chemotactic for ; induces lysosomal enzyme release from rabbit peritoneal neutrophils 1 *D000590 Amino Acid Chloromethyl Ketones Mol Cell Biochem 1981;41:19 RLS CCR CCR M0103842 N-formylnorleucyl-leucyl-phenylalanine chloromethyl ketone C0615620 L-Leucinamide, N-formyl-L-norleucyl-N-(3-chloro-2-oxo-1-(phenylmethyl)propyl)-, (S)- 81134-56-7 T133846 N-formylnorleucyl-leucyl-phenylalanine chloromethyl ketone T133844 FNLPCK T133845 N-formyl-Nle-Leu-Phe-chloromethyl ketone C033597 phenylalanyl-alanyl-arginine chloromethyl ketone 1982 03 15 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 urokinase active site inhibitor 2 *D000590 Amino Acid Chloromethyl Ketones Invest Ophthalmol Vis Sci 1982;22(2):191 MEG CCR CCR M0104163 phenylalanyl-alanyl-arginine chloromethyl ketone C0070641 L-Alaninamide, L-phenylalanyl-N-(4-((aminoiminomethyl)amino)-1-(chloroacetyl)butyl)-, (S)- 65319-55-3 T134167 phenylalanyl-alanyl-arginine chloromethyl ketone T134166 Phe-Ala-Arg-chloromethyl ketone T134165 Phe-Ala-Arg-CK C005145 nitrosoazetidine 1974 01 01 1982 10 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *AZETIDINES (75-82) *AZETINES (74-75) *D009602 Nitrosamines Cancer Res 33(7):1634;1973 NLM VSR NLM M0046471 nitrosoazetidine C0068859 15216-10-1 T076474 nitrosoazetidine C039809 2',3'-cyclic nucleotide 2'-phosphodiesterase 1983 12 13 2000 10 27 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 catalyzes the hydrolysis of the 2'-phosphodiesterase bond to yield nucleoside 3'phosphate 12 *D015087 2',3'-Cyclic-Nucleotide Phosphodiesterases RLS CCR CCR M0118944 2',3'-cyclic nucleotide 2'-phosphodiesterase C0045103 EC 3.1.4.16 T116 Amino Acid, Peptide, or Protein T126 Enzyme 9037-18-7 (CRN) T148948 2',3'-cyclic nucleotide 2'-phosphodiesterase T148947 2',3'-cyclic nucleotide 2'-phosphohydrolase C005149 phosphonoproteins 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *PHOSPHONIC ACIDS (73-76) *D010750 Phosphoproteins Biochemistry 12(15):2829;1973 NLM NLM M0046486 phosphonoproteins C0602149 0 T076489 phosphonoproteins C005152 lipostabil 1970 01 01 1994 08 26 1994 1995 1996 1997 1998 1999 2000 2001 2002 45 POLYENES (75-76) *D010713 Phosphatidylcholines D005217 Fat Emulsions, Intravenous Acta Med Pol 16(3):141;1975 Eur J Clin Pharmacol 15(1):15;1979 J Pathol 97(11):35;1969 Pol Med Sci Hist Bull 15(4):433;1975 Pol Przegl Chir 48(6):679;1976 Pol Tyg Lekar 31(40):1717;1976 NLM PML NLM M0046494 lipostabil C0065065 11096-62-1 M0046494 M0046492 M0046494 M0046493 T076497 lipostabil M0046492 lipostabil forte C0243241 M0046494 M0046492 T076495 lipostabil forte M0046493 polyenylphosphatidylcholine C0137759 M0046494 M0046493 T076496 polyenylphosphatidylcholine C006795 brilliant black 1974 01 01 2001 01 30 1998 1999 2000 2001 2001A 2002 1 *D001391 Azo Compounds Acta Histochem 45(2):317;1973 NLM TWD TWD M0049559 brilliant black C0602865 4197-00-6 M0049559 M0049558 T079562 brilliant black M0049558 C.I. 27260 C0602864 M0049559 M0049558 T079561 C.I. 27260 C005158 diaminodurene 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 5 *D010655 Phenylenediamines BBA 449:125;1976 Biochim Biophys Acta 305(1):105;1973 Biochim Biophys Acta 396(2):310;1975 NLM NLM M0046502 diaminodurene C0057705 3102-87-2 T076505 diaminodurene C038768 methoxysuccinate-alanyl-alanyl-valine chloromethyl ketone 1983 09 14 2001 01 30 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 *D000590 Amino Acid Chloromethyl Ketones D010196 Pancreatic Elastase Q000037 antagonists ; inhibitors Mol Immunol 1983;20(6):623 DLJ CCR CCR M0116513 methoxysuccinate-alanyl-alanyl-valine chloromethyl ketone C0619192 0 T146517 methoxysuccinate-alanyl-alanyl-valine chloromethyl ketone T146516 methoxysuccinate-Ala-Ala-Val-chloromethyl ketone T146515 MSAVCK C005161 poly(N(6)-benzoyldeoxyadenylate) 1976 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *POLY A (76-79) *POLYNUCLEOTIDES (74-76) ADENINE NUCLEOTIDES (74-78) DEOXYRIBONUCLEOTIDES (74-78) *D003838 Deoxyadenine Nucleotides *D011089 Polydeoxyribonucleotides Biochim Biophys Acta 308(1):35;1973 NLM NLM M0046508 poly(N(6)-benzoyldeoxyadenylate) C0602154 5'-Adenylic acid, N-benzoyl-2'-deoxy-, homopolymer 59033-76-0 T076511 poly(N(6)-benzoyldeoxyadenylate) C005162 poly(N(4)-anisoyldeoxycytidylate) 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *POLYDEOXYRIBONUCLEOTIDES *POLYNUCLEOTIDES (74-76) CYTOSINE NUCLEOTIDES (74-75) DEOXYRIBONUCLEOTIDES (74-75) *D003843 Deoxycytidine Monophosphate Biochim Biophys Acta 308(1):35;1973 NLM NLM M0046509 poly(N(4)-anisoyldeoxycytidylate) C0602155 Cytidine, 2'-deoxy-N-(4-methoxybenzoyl)-, homopolymer 41911-89-1 T076512 poly(N(4)-anisoyldeoxycytidylate) C041051 dansylalanyllysine chloromethyl ketone 1984 05 29 2001 01 30 1997 1998 1999 2000 2001 2001A 2002 fluorescent probe for localization of acrosin activity 1 *D000590 Amino Acid Chloromethyl Ketones *D003619 Dansyl Compounds J Histochem Cytochem 1984;32(5):526 DLJ CCR CCR M0121909 dansylalanyllysine chloromethyl ketone C0621004 Propanamide, N-(5-amino-1-(chloroacetyl)pentyl)-2-(((5-(dimethylamino)-1-naphthalenyl)sulfonyl)amino)-, (S-(R*,R*))- 70592-17-5 T151914 dansylalanyllysine chloromethyl ketone T151912 DALCK T151913 dansyl-Ala-Lys-chloromethyl ketone C005167 2,5-bis(2-chloroethylsulfonyl)pyrrole-3,4-dicarbonitrile 1973 01 01 1982 09 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 lipolytic agent 0 ACETONITRILES (75-76) MUSTARD COMPOUNDS (73-81) *D011758 Pyrroles J Lipid Res 14(2):250;1973 NLM VSR NLM M0046522 2,5-bis(2-chloroethylsulfonyl)pyrrole-3,4-dicarbonitrile C0602162 40380-34-5 T076525 2,5-bis(2-chloroethylsulfonyl)pyrrole-3,4-dicarbonitrile C005170 2,4-diamino-6-butoxy-s-triazine 1973 01 01 1982 09 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 lipolytic agent 0 DIAMINES (74-76) *D014227 Triazines J Lip Res 14(2):250;1973 NLM VSR NLM M0046524 2,4-diamino-6-butoxy-s-triazine C0602164 25254-67-5 T076527 2,4-diamino-6-butoxy-s-triazine C005171 2,3-dihydro-5,6-dimethyl-3-oxo-4-pyridazinecarbonitrile 1973 01 01 1982 09 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 lipolytic agent 0 NITRILES (73-76) *D011724 Pyridazines J Lip Res 14(2):250;1973 NLM VSR NLM M0046525 2,3-dihydro-5,6-dimethyl-3-oxo-4-pyridazinecarbonitrile C0602165 40380-36-7 T076528 2,3-dihydro-5,6-dimethyl-3-oxo-4-pyridazinecarbonitrile C047499 benzyloxycarbonylalanyl-alanyl phenylalanine chloromethyl ketone 1986 01 30 2001 01 30 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 subtilisin, thermitase ; chymotrypsin inhibitor 2 *D000590 Amino Acid Chloromethyl Ketones Biomed Biochim Acta 1985;44(7-8):1089 MEG CCR CCR M0137154 benzyloxycarbonylalanyl-alanyl phenylalanine chloromethyl ketone C0081747 86832-16-8 T167159 benzyloxycarbonylalanyl-alanyl phenylalanine chloromethyl ketone T167158 benzyloxycarbonyl-Ala-Ala-Phe-chloromethyl ketone T167157 Z-Ala-Ala-Phe-CH2CL C051330 glutamyl-glycyl-arginine chloromethyl ketone 1987 03 12 2001 01 30 1998 1999 2000 2001 2001A 2002 RN given refers to (S)-isomer 4 *D000590 Amino Acid Chloromethyl Ketones D014568 Urinary Plasminogen Activator Q000037 antagonists ; inhibitors Eur J Biochem 1987;162(2):351 MEG CCR CCR M0146133 glutamyl-glycyl-arginine chloromethyl ketone C0119532 65113-67-9 M0146133 M0146132 T176138 glutamyl-glycyl-arginine chloromethyl ketone T176136 GGACK M0146132 Glu-Gly-Arg-chloromethane C0119346 M0146133 M0146132 T176137 Glu-Gly-Arg-chloromethane C035859 15-hydroxyprostaglandin dehydrogenase 1982 10 28 2000 10 27 1997 1998 1999 2000 2000A 2001 2001A 2001B 2002 catalyzes reversibly the oxidation of 11 alpha, 15-dihydroxy-9-ketoprost-13-enoate to 11 alpha-9,15-diketoprost-13-enoate in presence of NAD 177 *D006911 Hydroxyprostaglandin Dehydrogenases Methods Enzymol 1982;86:126 VSR CCR CCR M0109627 15-hydroxyprostaglandin dehydrogenase C0044894 EC 1.1.1.141 T116 Amino Acid, Peptide, or Protein T126 Enzyme 9030-87-9 (CRN) T139631 15-hydroxyprostaglandin dehydrogenase T139623 15-HPDnase T139625 15-hydroxy-PG dehydrogenase T139626 15-hydroxyprostaglandin dehydrogenase (NAD+) T139627 15-ketoprostaglandin reductase T139624 15-PGDH, type-I T139628 NAD+-dependent 15-hydroxyprostaglandin dehydrogenase T139629 prostaglandin-15-hydroxydehydrogenase T139630 type-I 15-PGDH C005188 Mandrax 1968 01 01 1982 07 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains methaqualone; diphenhydramine 1 *D004155 Diphenhydramine *D008702 Methaqualone D004338 Drug Combinations NLM VSR NLM M0046552 Mandrax C0065638 8076-99-1 T076555 Mandrax C006801 brocillin 1974 01 01 2001 01 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *PENICILLIN (74-75) PHENYL ETHERS (74-75) D010404 Penicillin V *Q000031 analogs ; derivatives Lille Med 19(2):204;1974 NLM TWD TWD M0049575 brocillin C0602868 1245-44-9 T079578 brocillin T079577 alpha-phenoxy propylpenicillin C018763 1-acylglycerol-3-phosphate O-acyltransferase 1973 01 01 2000 10 27 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 42 COENZYME A (73-78) GLYCEROPHOSPHATES (78-81) PHOSPHOLIPIDS (73-78) *D000217 Acyltransferases Eur J Biochem 84:61;1978 J Biol Chem 248(14):5197;1973 Lipids 13(5):329;1978 NLM CCR CCR M0070640 1-acylglycerol-3-phosphate O-acyltransferase C0243546 EC 2.3.1.51 T116 Amino Acid, Peptide, or Protein T126 Enzyme 51901-16-7 (CRN) M0070640 M0070635 T100643 1-acylglycerol-3-phosphate O-acyltransferase T100637 1-acylglycerophosphate acyltransferase T100636 1-AGP-acyltransferase T100639 acyl CoA-1-acyl-syn-glycerol-3-phosphate O-acyltransferase T100640 acyl CoA-monoacylglycerophosphateacyltransferase T100641 acyl coenzyme A-monacylglycerophosphateacyltransferase T100642 plsC gene product M0070635 1-palmitylglycerol 3-phosphate acyltransferase C0950384 T116 Amino Acid, Peptide, or Protein T126 Enzyme M0070640 M0070635 T100638 1-palmitylglycerol 3-phosphate acyltransferase C005202 N-methyl-4-aminoazobenzene 1968 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 17 *AZO COMPOUNDS (68-76) ANILINE COMPOUNDS (73-76) D010128 p-Aminoazobenzene *Q000031 analogs ; derivatives Cancer Res 1979;39(9):3411 Cancer Res 36(3):1196;1976 J Biol Chem 252(11):3970;1977 NLM RLS NLM M0046577 N-methyl-4-aminoazobenzene C0068078 621-90-9 T076580 N-methyl-4-aminoazobenzene C005210 5-methylpyrazole-3-carboxylic acid 1970 01 01 1980 01 21 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 10 *CARBOXYLIC ACIDS (73-76) *D011720 Pyrazoles Arzneim Forsch 25(1):117;1975 Biochem Med 1979;22(2):204 NLM RLS NLM M0046584 5-methylpyrazole-3-carboxylic acid C0049314 402-61-9 T076587 5-methylpyrazole-3-carboxylic acid C005211 N'-methyl-2-pyridone-5-carboxamide 1970 01 01 1992 06 18 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 18 *NICOTINAMIDE (70-75) D009536 Niacinamide *Q000031 analogs ; derivatives Acta Vitaminol Enzymol (Milano) 29:52;1975 Cancer Res 38:697;1978 Chem Biol Interact 18(1):101;1977 NLM MLH TPW M0046586 N'-methyl-2-pyridone-5-carboxamide C0067107 701-44-0 M0046586 M0046585 T076589 N'-methyl-2-pyridone-5-carboxamide M0046585 1-methyl-5-carboxylamide-2-pyridone C0089520 M0046586 M0046585 T076588 1-methyl-5-carboxylamide-2-pyridone C005215 Fast Red S 1969 01 01 1998 01 05 1998 1999 2000 2001 2002 4 NAPHTHALENESULFONATES (74-82) *D001391 Azo Compounds NLM IDX NLM M0046592 Fast Red S C0602175 4-(2-hydroxy-1-naphthylazo)-1-naphthalenesulfonic acid 1658-56-6 T076595 Fast Red S C024223 vitamin MK 8 1980 05 14 2001 09 05 2002 isoprenoid acetone-soluble lipid 5 *LIPIDS (1980-1980) VITAMIN K/*analogs ; derivatives (1979-2001) D024482 Vitamin K 2 *Q000031 analogs ; derivatives Can J Microbiol 1979;25(11):1288 MEG lkt sjn M0082192 vitamin MK 8 C0084980 (all-E)-2-methyl-3-(3,7,11,15,19,23,27,31-octamethyl-2,6,10,14,18,22,26,30-dotriacontaoctaenyl)-1,4-naphthalenedione 523-38-6 T109 Organic Chemical T127 Vitamin T112195 vitamin MK 8 T112194 menaquinone 8 C063351 isoleucyl-phenylalanyl-lysine chloromethyl ketone 1990 04 11 2001 01 30 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given is for cpd with L-Ile 1 *D000590 Amino Acid Chloromethyl Ketones D007610 Kallikreins Q000037 antagonists ; inhibitors Chem Pharm Bull 1989;37(11):3108 WMM CCR CCR M0174922 isoleucyl-phenylalanyl-lysine chloromethyl ketone C0640390 126642-86-2 126583-13-9 (D-Ile) M0174922 M0324618 T204927 isoleucyl-phenylalanyl-lysine chloromethyl ketone T204926 Ile-Phe-Lys-CH2Cl M0324618 isoleucyl-phenylalanyl-lysine chloromethyl ketone, D-Ile isomer C0958213 126583-13-9 M0174922 M0324618 T354618 isoleucyl-phenylalanyl-lysine chloromethyl ketone, D-Ile isomer 1999 08 18 C006811 bromochloromethane 1969 01 01 2001 01 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 inhibitor of ruminal methane production 9 *BROMINE (69-75) *METHYL CHLORIDE (74-75) HALOGENS (75-81) METHANE/*analogs (75-83) *D006846 Hydrocarbons, Halogenated J Animal Sci 38(4):908;1974 NLM TWD TWD M0049587 bromochloromethane C0054114 74-97-5 T079590 bromochloromethane T079589 chlorobromomethane C065676 benzyloxycarbonylphenylalanyl-alanine chloromethyl ketone 1990 10 16 2001 01 30 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 2 *D000590 Amino Acid Chloromethyl Ketones Biochem Biophys Res Commun 1990;171(2):711 TPW CCR CCR M0180517 benzyloxycarbonylphenylalanyl-alanine chloromethyl ketone C0081748 60525-17-9 T210522 benzyloxycarbonylphenylalanyl-alanine chloromethyl ketone T210520 Boc-Phe-Ala-CMK T210521 ZPACK C005228 methyl-12-hydroxystearate 1973 01 01 1982 09 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 *FATTY ACIDS (73-75) FATTY ALCOHOLS (73-82) *D013228 Stearates NLM VSR NLM M0046623 methyl-12-hydroxystearate C0162945 methyl-12-hydroxyoctadecanoate 141-23-1 T076626 methyl-12-hydroxystearate C006825 5-bromouridylyl-(3'-5')adenosine 1975 01 01 2001 01 30 1995 1996 1997 1998 1999 2000 2001 2001A 2002 dinucleoside monophosphate 0 *URACIL NUCLEOTIDES (75-88) ADENOSINE/*analogs (75-88) *D015226 Dinucleoside Phosphates J Bact 120(2):831;1974 NLM TWD TWD M0049612 5-bromouridylyl-(3'-5')adenosine C0602886 Adenosine, 5-bromouridylyl-(3'-5')- 53892-50-5 T079615 5-bromouridylyl-(3'-5')adenosine T079614 BUY-ADO C404783 Miralax 2000 03 07 2001 09 10 2000 2001 2001A 2002 a tasteless laxative composed of PEG3350; Miralax is tradename 3 *D011092 Polyethylene Glycols Am J Gastroenterol 2000 Feb;95(2):446-50 BMB CCR CCR M0358266 Miralax C0876088 0 T109 Organic Chemical T121 Pharmacologic Substance M0358266 M0397863 T408614 Miralax 2000 03 07 M0397863 Braintree PEG laxative C0919373 T109 Organic Chemical T121 Pharmacologic Substance M0358266 M0397863 T408615 Braintree PEG laxative 2000 03 07 C005236 6-methylsalicylic acid 1970 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 9 *D012461 Salicylic Acids NLM NLM M0046638 6-methylsalicylic acid C0049664 567-61-3 T076641 6-methylsalicylic acid C005243 morphactins 1968 01 01 1997 06 09 1997 1998 1999 2000 2001 2002 fluorenol-9-carboxylic acid derivs Chemline lists nine morphactins 3 CARBOXYLIC ACIDS (75-76) *D005449 Fluorenes J Ultrastruct Res 59(2):140;1977 NLM TBT NLM M0046645 morphactins C0066806 0 T076648 morphactins C005292 perthane 1974 01 01 2000 06 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 structure 2 *HYDROCARBONS, CHLORINATED (74-78) *INSECTICIDES, ORGANOCHLORINE (74-78) D003632 DDD *Q000031 analogs ; derivatives Prob Endokrinol 24(1):95;1978 NLM CCR CCR M0046743 perthane C0070475 72-56-0 T109 Organic Chemical T131 Hazardous or Poisonous Substance T076746 perthane T076745 1,1-dichloro-2,2-bis(p-ethylphenyl)ethane C005347 alpha-phenyltetrahydrofuranone-2-gamma-carboxylic acid 1973 01 01 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 0 CARBOXYLIC ACIDS (73-76) *D005663 Furans Arch Immunol Ther Exp 21(20):309;1973 Arch Immunol Ther Exp 25(6):819;1977 NLM TWD TWD M0046828 alpha-phenyltetrahydrofuranone-2-gamma-carboxylic acid C0051457 22073-32-1 13389-96-3 (Na salt) M0046828 M0309057 T076831 alpha-phenyltetrahydrofuranone-2-gamma-carboxylic acid M0309057 alpha-phenyltetrahydrofuranone-2-gamma-carboxylic acid, sodium salt C0951366 13389-96-3 M0046828 M0309057 T339057 alpha-phenyltetrahydrofuranone-2-gamma-carboxylic acid, sodium salt 1999 08 18 C025164 fucoxanthin 1980 07 11 2001 09 12 2002 RN given refers to (3S,3'S,5R,5'R,6S,6'R)-isomer 24 *CAROTENOIDS (1980-2001) *D024341 Xanthophylls Biochim Biophys Acta 1980;590(3):309 MEG jmp BVL M0084213 fucoxanthin C0060808 beta,beta-carotene, 3'-(acetyloxy)-6',7'-didehydro-5,6-epoxy-5,5',6,6',7,8-hexahydro-3,5'-dihydroxy-8-oxo-, (3S,3'S,5R,5'R,6S,6'R)- 3351-86-8 T109 Organic Chemical 17257-05-5 ((3S,3'S,5R,5'R,6S,6'R,cis)-isomer) 55659-36-4 ((6'R,13-cis)-isomer) 55659-37-5 ((6'R,13'-cis)-isomer) 55659-38-6 ((6'S)-isomer) M0084213 M0316224 M0084213 M0316226 M0084213 M0316225 M0084213 M0316227 T114216 fucoxanthin Merck Index, 9th ed, #4132 M0316224 fucoxanthin, (3S,3'S,5R,5'R,6S,6'R,cis)-isomer C0953788 17257-05-5 T109 Organic Chemical M0084213 M0316224 T346224 fucoxanthin, (3S,3'S,5R,5'R,6S,6'R,cis)-isomer 1999 08 18 M0316226 fucoxanthin, (6'R,13'-cis)-isomer C0953790 55659-37-5 T109 Organic Chemical M0084213 M0316226 T346226 fucoxanthin, (6'R,13'-cis)-isomer 1999 08 18 M0316225 fucoxanthin, (6'R,13-cis)-isomer C0953789 55659-36-4 T109 Organic Chemical M0084213 M0316225 T346225 fucoxanthin, (6'R,13-cis)-isomer 1999 08 18 M0316227 fucoxanthin, (6'S)-isomer C0953791 55659-38-6 T109 Organic Chemical M0084213 M0316227 T346227 fucoxanthin, (6'S)-isomer 1999 08 18 C079507 N-formimidoyl fortimicin A synthase 1993 03 04 2001 01 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; an oxidase that converts fortimicin A and glycine to N-formimidoyl fortimicin A; requires O2 and FAD 1 *D000594 Amino Acid Oxidoreductases Mol Gen Genet 1992 Dec;236(1):49-59 BVL CCR CCR M0212811 N-formimidoyl fortimicin A synthase C0657108 EC 1.4.3.- T242816 N-formimidoyl fortimicin A synthase T242814 FI-FTMase T242815 fms 14 gene product C013326 Ulcrux powder 1977 01 01 2000 07 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 for treatment of skin ulcers; contains tetracycline, dehydroacetic acid, hydroxypolyethoxydodecane 0 POWDERS (77-82) *D011092 Polyethylene Glycols *D013752 Tetracycline D004338 Drug Combinations Fortschr Med 94(19):1148;1976 NLM WXM WXM M0060997 Ulcrux powder C0605647 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-, mixt. with 3-acetyl-6-methyl-2H-pyran-2,4(3H)-dione monosodium salt 78891-91-5 T109 Organic Chemical T121 Pharmacologic Substance T091000 Ulcrux powder C020268 dansyl-L-arginine 1979 01 01 2000 07 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 2 DANSYL COMPOUNDS (79-80) D001120 Arginine *Q000031 analogs ; derivatives J Biochem (Tokyo) 85(4):961;1979 NLM CCR CCR M0073848 dansyl-L-arginine C0057117 N(2)-((5-(dimethylamino)-1-naphthalenyl)sulfonyl)-L-arginine 28217-22-3 T116 Amino Acid, Peptide, or Protein T103851 dansyl-L-arginine C005308 nitroxoline 1969 01 01 2001 01 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure in Merck Index, 9th ed, #6475; RN given refers to parent cpd 32 *8-HYDROXYQUINOLINE/analogs (75-79) *QUINOLINES (69-75) HYDROXYQUINOLINE/analogs (79-81) NITRO COMPOUNDS (73-79) *D009600 Nitroquinolines Antibiotiki 1979;24(12):921 Antibiotikii 21(9):809;1976 Cesk Epidemiol Mikrobiol Immunol 24(2):97;1975 Int J Clin Pharmacol Biopharm 1979;17(12):476 Lijec Vjesn 93(3):339;1971 Med Arh 29(6):643;1975 S Afr Med J 54(23):959;1978 Sov Med 1979;(11):43 Vutr Boles 16(3):94;1977 NLM CCR CCR M0046773 nitroxoline C0068881 4008-48-4 T109 Organic Chemical T121 Pharmacologic Substance D000892 Anti-Infective Agents, Urinary D000935 Antifungal Agents 75640-18-5 (K salt) 81117-08-0 (mono-F) M0046773 M0308998 M0046773 M0308999 T076776 nitroxoline Merck Index, 9th ed, #6475 Negwer, 5th ed, #921 USAN 1981, p.263 T076773 5-nitro-8-hydroxyquinoline T076774 5-nitroquinolin-8-ol T076775 5-nitrox T076772 5-NOK M0308998 nitroxoline, potassium salt C0951361 75640-18-5 T109 Organic Chemical T121 Pharmacologic Substance M0046773 M0308998 T338998 nitroxoline, potassium salt 1999 08 18 M0308999 nitroxoline monofluoride C0951362 81117-08-0 T109 Organic Chemical T121 Pharmacologic Substance M0046773 M0308999 T338999 nitroxoline monofluoride 1999 08 18 C098372 P457 carotenoid 1996 04 01 2001 09 12 2002 isolated from some dinoflagellates; structure in first source 1 *D002338 Carotenoids D007785 Lactose *Q000031 analogs ; derivatives J Nat Prod 1995 Nov;58(11):1675-82 THA jmp BVL M0258418 P457 carotenoid C0387330 0 T109 Organic Chemical T123 Biologically Active Substance T288423 P457 carotenoid C033275 SK;F 93479 1982 03 09 2001 01 12 1995 1996 1997 1998 1999 2000 2001 2001A 2002 inhibits nocturnal acid secretion 38 *D011744 Pyrimidinones Lancet 1982;1(8265):224 RLS TWD TWD M0103321 SK;F 93479 C0074640 4(1H)-Pyrimidinone, 2-((2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)amino)-5-((6-methyl-3-pyridinyl)methyl)-, trihydrochloride 72716-75-7 T109 Organic Chemical T121 Pharmacologic Substance D006635 Histamine H2 Antagonists M0103321 M0103318 T133325 SK;F 93479 T133323 SK;F-93479 T133324 SKF 93479 M0103318 2-(2-(5-dimethylaminomethylfuran-2-ylmethylthio)ethylamino)-5-(6-methylpyrid-3-ylmethyl)pyrimid-4-one C0091975 T109 Organic Chemical T121 Pharmacologic Substance M0103321 M0103318 T133322 2-(2-(5-dimethylaminomethylfuran-2-ylmethylthio)ethylamino)-5-(6-methylpyrid-3-ylmethyl)pyrimid-4-one C006899 carbonylbis(L-methionine 4-nitrophenyl ester) 1975 01 01 2001 01 30 1997 1998 1999 2000 2001 2001A 2002 reagent for reversible intramolecular cross-linking of insulin 0 *METHIONINE (75-76) NITROBENZENES (75-82) D008715 Methionine *Q000031 analogs ; derivatives J Am Chem Soc 96(18):5947;1974 NLM TWD TWD M0049732 carbonylbis(L-methionine 4-nitrophenyl ester) C0054715 L-Methionine, N,N'-carbonylbis-, bis(4-nitrophenyl) ester 53751-62-5 T079735 carbonylbis(L-methionine 4-nitrophenyl ester) T079734 carbonylbis(L-methionine p-nitrophenylester) C029321 calcium potassium ATPase 1981 05 18 2001 01 12 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 14 *D000251 Adenosinetriphosphatase Biochim Biophys Acta 1981;641(1):242 MEG WXM WXM M0093579 calcium potassium ATPase C0054481 EC 3.6.1.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T123582 calcium potassium ATPase T123581 potassium calcium ATPase T123580 K Ca ATPase T123579 Ca K ATPase T123578 ATPase, potassium calcium T123577 ATPase, calcium potassium T123576 (Ca++ + K+)-ATPase C410182 OFU 001 2000 07 05 2000 2001 2002 structure in first source 2 D005472 Fluorouracil *Q000031 analogs ; derivatives Jpn J Cancer Res 2000 Apr;91(4):433-8 BMB BMB M0365330 OFU 001 C0915325 0 T114 Nucleic Acid, Nucleoside, or Nucleotide T418247 OFU 001 2000 07 05 T418248 1-(2'-oxopropyl)-5-fluorouracil 2000 07 05 T418249 OFU001 2000 07 05 C041057 5(4'-hydroxybenzylidenoimino)-3-methylisothiazolo(5,4-d)pyrimidine-(7H)-4,6-dione 1984 05 30 2001 02 02 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source; do not confuse with IP-10 protein 24 *D011744 Pyrimidinones Arch Immunol Ther Exp (Warsz) 1983;31(5):769 MEG TWD TWD M0121919 5(4'-hydroxybenzylidenoimino)-3-methylisothiazolo(5,4-d)pyrimidine-(7H)-4,6-dione C0377673 89367-92-0 T109 Organic Chemical T121 Pharmacologic Substance D000970 Antineoplastic Agents M0121919 M0121921 T151924 5(4'-hydroxybenzylidenoimino)-3-methylisothiazolo(5,4-d)pyrimidine-(7H)-4,6-dione M0121921 IP 10 C0377674 T109 Organic Chemical T121 Pharmacologic Substance M0121919 M0121921 T151926 IP 10 T151925 IP-10 C031652 anion-sensitive ATPase 1981 10 05 2001 02 02 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 anion sensitive 64 *D000251 Adenosinetriphosphatase D001639 Bicarbonates Biochem Biophys Acta 1981;644(2):251 Biochim Biophys Acta 1981;648(2):186 MEG WXM WXM M0099272 anion-sensitive ATPase CT069837 EC 3.6.1.- T116 Amino Acid, Peptide, or Protein T126 Enzyme M0099272 M0099274 M0099272 M0099269 T129276 anion-sensitive ATPase T129277 chloride-bicarbonate ATPase M0099274 bicarbonate ATPase CT069839 0 T116 Amino Acid, Peptide, or Protein T126 Enzyme M0099272 M0099274 T129278 bicarbonate ATPase T129272 ATPase, bicarbonate T129275 HCO(3)-ATPase M0099269 ATPase, chloride C0109973 0 T116 Amino Acid, Peptide, or Protein T126 Enzyme M0099272 M0099269 T129273 ATPase, chloride T129274 Cl ATPase C005316 nybomycin 1973 01 01 1993 05 17 1994 1995 1996 1997 1998 1999 2000 2001 2002 antibiotic substance produced by Streptomyces A 717; structure 1 PYRIDINES (73-79) QUINOLINES (73-88) D015363 Quinolones J Am Chem Soc 98(16):5012;1976 J Am Chem Soc 99(14):4647;1977 NLM BXB TPW M0046788 nybomycin C0069172 8,9-dihydro-4-(hydroxymethyl)-6,9-dimethyl-2,8- dioxopyrido(3,2-g)quinoline-1(2H)-carboxaldehyde 30408-30-1 T076791 nybomycin Merck Index, 9th ed, p.874, #6543 C005341 N-ethylaminopropiophenone 1973 01 01 1993 04 16 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 major metabolite of diethylpropion in man under acidic urine conditions 0 *PROPIOPHENONES (73-75) ETHYLAMINES (73-75) D004053 Diethylpropion *Q000031 analogs ; derivatives J Pharm Pharmacol 25(2):119;1973 NLM TPW NLM M0046823 N-ethylaminopropiophenone C0602184 18259-37-5 T076826 N-ethylaminopropiophenone C005343 N-diethylnorpseudoephedrine 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 major metabolite of diethylpropion in man under acidic urine conditions; structure 0 *PHENETHYLAMINES (73-75) *PROPANOLAMINES (74-75) D010665 Phenylpropanolamine *Q000031 analogs ; derivatives J Pharm Pharmacol 25(2):119;1973 NLM NLM M0046825 N-diethylnorpseudoephedrine C0602186 37025-60-8 T076828 N-diethylnorpseudoephedrine C434348 4-(4-Methoxyphenylamino)-3-phenylazo-3-penten-2-one 2001 09 10 2001 09 10 2001 2001A 2001B 2002 structure in first source 1 *D001391 Azo Compounds *D010422 Pentanones Acta Crystallogr C 2001 Jun;57(Pt 6):737-9 SZM SZM SZM M0397750 4-(4-Methoxyphenylamino)-3-phenylazo-3-penten-2-one C0969487 0 T109 Organic Chemical T460902 4-(4-Methoxyphenylamino)-3-phenylazo-3-penten-2-one 2001 09 10 T460903 4-(MPA)-PAP 2001 09 10 C005351 1-aminoglucose 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D005944 Glucosamine FEBS Letters 33(1):93;1973 NLM NLM M0046832 1-aminoglucose C0602189 30104-32-6 T076835 1-aminoglucose C005353 3-hydroxymethylfuran N,N-diethylcarbamate 1974 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 synthetic analog of ngaione 0 FURANS (74-82) *D002219 Carbamates J Pathol 109(1):xiv;1973 NLM VSR NLM M0046833 3-hydroxymethylfuran N,N-diethylcarbamate C0602190 diethylcarbamic acid 3-furanylmethyl ester 50884-34-9 T076836 3-hydroxymethylfuran N,N-diethylcarbamate C005359 4-methylumbelliferyl phosphate 1974 01 01 1998 02 11 1998 1999 2000 2001 2002 31 *COUMARINS (74-75) ORGANOPHOSPHORUS COMPOUNDS (74-82) D006923 Hymecromone *Q000031 analogs ; derivatives Clin Chem 19(8):871;1973 Metabolism 27(7):801;1978 NLM BQV NLM M0046852 4-methylumbelliferyl phosphate C0048519 3368-04-5 D007202 Indicators and Reagents T076855 4-methylumbelliferyl phosphate C005371 dexa biciron 1974 01 01 1995 07 28 1996 1997 1998 1999 2000 2001 2002 combination of dexamethasone isonicotinate ; tramazoline 0 *DEXAMETHASONE (74-76) *D003908 Dexamethasone Isonicotinate *D007093 Imidazoles D004338 Drug Combinations D009883 Ophthalmic Solutions Z Allgemein Med 49(7):330;1973 NLM MLH BVL M0046868 dexa biciron C0057585 Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-((4-pyridinylcarbonyl)oxy)-, (11beta,16alpha)-, mixt. with 4,5-dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-1H-imidazol-2-amine monohydrochloride 76448-25-4 T076871 dexa biciron C005372 3-pentadecylveratrole 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ALKANES (74-76) METHYL ETHERS (74-75) *D002396 Catechols Adv Biol Skin 11(0):161;1971 NLM NLM M0046869 3-pentadecylveratrole C0602201 7461-75-8 T076872 3-pentadecylveratrole C005374 dipiridilium 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D011726 Pyridinium Compounds Resuscitation 2(1):9;1973 NLM NLM M0046870 dipiridilium C0602202 0 T076873 dipiridilium C005375 isothiazolecarboxylic acid 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CARBOXYLIC ACIDS (73-76) *D013844 Thiazoles Arch Immunol Ther Exp (Warsz) 21(2):329;1973 NLM NLM M0046871 isothiazolecarboxylic acid C0064085 0 T076874 isothiazolecarboxylic acid C005377 N-acetylsulfapyridine 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 9 *SULFANILAMIDE (73-75) PYRIDINES (73-75) D013427 Sulfapyridine *Q000031 analogs ; derivatives New Engl J Med 289:491;Sept1973 NLM RLS NLM M0046873 N-acetylsulfapyridine C0067786 19077-98-6 T076876 N-acetylsulfapyridine C005378 sulfapyridine-O-glucuronide 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *SULFANILAMIDE (73-75) GLUCURONATES (73-82) PYRIDINES (73-75) D013427 Sulfapyridine *Q000031 analogs ; derivatives N Engl J Med 289:491;1973 NLM RLS NLM M0046874 sulfapyridine-O-glucuronide C0602203 0 T076877 sulfapyridine-O-glucuronide C005379 acetylsulfapyridine-O-glucuronide 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *SULFANILAMIDE (73-75) GLUCURONATES (73-82) PYRIDINES (73-75) D013427 Sulfapyridine *Q000031 analogs ; derivatives New Engl J Med 289:491;Sept1973 NLM RLS NLM M0046875 acetylsulfapyridine-O-glucuronide C0602204 beta-D-Glucopyranosiduronic acid, 6-(((4-(acetylamino)phenyl)sulfonyl)amino)-3-pyridinyl 69233-18-7 T076878 acetylsulfapyridine-O-glucuronide C005387 acetyl sulfisoxazole 1968 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *SULFISOXAZOLE (68-75) D013444 Sulfisoxazole *Q000031 analogs ; derivatives NLM NLM M0046886 acetyl sulfisoxazole C0081437 80-74-0 T076889 acetyl sulfisoxazole C004660 clorophene 1974 01 01 2001 07 14 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 13 *PHENOLS (74-75) BENZYL COMPOUNDS (74-75) D004003 Dichlorophen *Q000031 analogs ; derivatives NLM TWD TWD M0045798 clorophene C0055942 5-chloro-2-hydroxydiphenylmethane 120-32-1 3184-65-4 (Na salt) 35471-49-9 (K salt) M0045798 M0308668 M0045798 M0308667 M0045798 M0045795 T075801 clorophene Merck Index, 9th ed, #2364 T075797 2-benzyl-4-chlorophenol T075799 o-benzyl-p-chlorophenol T075800 ortho-benzyl-para-chlorophenol M0308668 clorophene potassium salt C0951282 35471-49-9 M0045798 M0308668 T338668 clorophene potassium salt 1999 08 18 M0308667 clorophene sodium salt C0951281 3184-65-4 M0045798 M0308667 T338667 clorophene sodium salt 1999 08 18 M0045795 Orthosan C0134204 M0045798 M0045795 T075798 Orthosan C005393 2-phosphonopropionate 1973 01 01 1982 08 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN given refers to parent acid; structure 2 *ORGANOPHOSPHORUS COMPOUNDS (73-82) *PROPIONATES (73-75) *D011426 Propionic Acids JNCI 56(4):823;1976 NLM VSR NLM M0046904 2-phosphonopropionate C0046533 5962-41-4 T076907 2-phosphonopropionate C005464 2-aminothiophenol 1972 01 01 2001 01 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 11 SULFHYDRYL COMPOUNDS (72-81) *D000814 Aniline Compounds J Pharm Sci 1980;69(1):106 NLM WXM WXM M0047032 2-aminothiophenol C0051679 137-07-5 3292-42-0 (HCl) M0047032 M0309122 T077035 2-aminothiophenol T077034 o-aminothiophenol M0309122 2-aminothiophenol hydrochloride C0951390 3292-42-0 M0047032 M0309122 T339122 2-aminothiophenol hydrochloride 1999 08 18 C408562 N-methyl-N-propyl amphetamine 2000 06 01 2000 06 05 2000 2000A 2000B 2001 2002 structure in first source 1 *D000662 Amphetamines Xenobiotica 2000 Mar;30(3):297-306 SZM BMB BMB M0363331 N-methyl-N-propyl amphetamine C0914473 0 T109 Organic Chemical M0363331 M0363332 T415688 N-methyl-N-propyl amphetamine 2000 06 01 M0363332 MPA amphetamine C0914474 M0363331 M0363332 T415689 MPA amphetamine 2000 06 01 C005411 parabanic acid 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 6 *D007093 Imidazoles NLM NLM M0046936 parabanic acid C0070059 imidazolidinetrione 120-89-8 T076939 parabanic acid Merck Index, 9th ed, p. 910, #6827 C022074 sodium tetrametaphosphate 1980 01 01 2000 06 05 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 RN given refers to metaphosphoric acid, tetra-Na salt 5 *D011122 Polyphosphates J Agric Food Chem 27(4):906;1979 NLM CCR CCR M0077705 sodium tetrametaphosphate C0074772 13396-41-3 T131 Hazardous or Poisonous Substance T197 Inorganic Chemical 14700-23-3 (unspecified Na salt) 17031-96-8 (tetra-Na salt monohydrate) M0077705 M0077704 M0077705 M0314696 T107708 sodium tetrametaphosphate T107706 cyclophos M0077704 cyclotetraphosphate C0111629 T131 Hazardous or Poisonous Substance T197 Inorganic Chemical M0077705 M0077704 T107707 cyclotetraphosphate M0314696 sodium tetrametaphosphate, monohydrate C0890531 17031-96-8 T131 Hazardous or Poisonous Substance T197 Inorganic Chemical M0077705 M0314696 T344696 sodium tetrametaphosphate, monohydrate 1999 08 18 C100030 endothall 1982 10 22 2001 07 14 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 minor descriptor (72-82); online ; Index Medicus search DICARBOXYLIC ACIDS (72-82) 21 minor descriptor (72-82); file maintained to DICARBOXYLIC ACIDS *D003998 Dicarboxylic Acids Bull Environ Contam Toxicol 1980;25(4):676 VSR TWD TWD M0262421 endothall C0059276 145-73-3 129-67-9 (di-Na salt) 17439-94-0 (di-NH4 salt) 2164-07-0 (di-K salt) 67021-64-1 (di-Na salt(endo,endo)-isomer) M0262421 M0327247 M0262421 M0327245 M0262421 M0327248 M0262421 M0327246 T292426 endothall M0327247 endothall dipotassium salt C0303937 2164-07-0 M0262421 M0327247 T357247 endothall dipotassium salt 1999 08 18 M0327245 endothall disodium salt C0303936 129-67-9 M0262421 M0327245 T357245 endothall disodium salt 1999 08 18 M0327248 endothall disodium salt, (endo,endo)-isomer C0959895 67021-64-1 M0262421 M0327248 T357248 endothall disodium salt, (endo,endo)-isomer 1999 08 18 M0327246 endothall, diammonium salt C0959894 17439-94-0 M0262421 M0327246 T357246 endothall, diammonium salt 1999 08 18 C064142 diclofenac hydroxyethylpyrrolidine 1990 06 18 2001 07 14 1997 1998 1999 2000 2001 2001A 2002 15 D004008 Diclofenac *Q000031 analogs ; derivatives Eur J Clin Pharmacol 1990;38(2):207 TPW TWD TWD M0176789 diclofenac hydroxyethylpyrrolidine C0082274 119623-66-4 M0176789 M0176784 T206794 diclofenac hydroxyethylpyrrolidine T206787 DHEP T206793 diclofenac-epolamine T206792 diclofenac-N-(2-hydroxyethyl) pyrrolidine T206788 DIEP T206790 N-(2-hydroxyethyl)pyrrolidinium (2-((2,6-dichlorophenyl)amino)phenyl)acetate T206791 diclofenac 1-(2-hydroxyethyl)pyrrolidinium salt M0176784 Flector C0526575 M0176789 M0176784 T206789 Flector C006068 propylparaben 1976 01 01 2001 01 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to cpd with hydroxy group locant in position 4; structure 72 *D010226 Parabens D013526 Surgical Mesh Dtsch Zahnaerztl Z 29(11):1018;1974 Oral Surg 43(1):32;1977 Zahn Mund Kieferheilkd 1979;67(6):579 NLM CCR CCR M0048132 propylparaben C0072238 4-hydroxybenzoic acid, propyl ester 94-13-3 35285-69-9 (mono-Na salt) 37870-43-2 (cpd with hydroxy group locant in position 3(or 4)) M0048132 M0048126 M0048132 M0309432 M0048132 M0309431 M0048132 M0048128 T078135 propylparaben Merck Index, 9th ed, p. 1018, #7655 Negwer, 4th ed, #1134 USAN 1980, p. 270 T078128 4-hydroxybenzoic acid propyl ester T078132 p-hydroxybenzoic acid propyl ester T078133 propyl 4-hydroxybenzoate T078134 propyl p-hydroxybenzoate T078130 PEPH M0048126 Bayer D 206 C0105323 M0048132 M0048126 T078129 Bayer D 206 M0309432 3(or 4)-hydroxybenzoic acid propyl ester C0951484 37870-43-2 M0048132 M0309432 T339432 3(or 4)-hydroxybenzoic acid propyl ester 1999 08 18 M0309431 propylparaben, monosodium salt C0894985 35285-69-9 M0048132 M0309431 T339431 propylparaben, monosodium salt 1999 08 18 M0048128 Nipazol C0132529 M0048132 M0048128 T078131 Nipazol C045238 N,N-diethyl-2-chloroethylamine 1985 06 13 2001 07 14 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd 2 *D004048 Diethylamines D000395 Air Pollutants, Occupational Gig Tr Prof Zabol 1985;(2):54 RLS TWD TWD M0131647 N,N-diethyl-2-chloroethylamine C0067355 100-35-6 67845-39-0 (sulfate [1:1]) 68391-41-3 (sulfate [2:1]) 869-24-9 (HCl) M0131647 M0322200 M0131647 M0322198 M0131647 M0322199 T161652 N,N-diethyl-2-chloroethylamine T161651 beta-diethylaminoethyl chloride M0322200 N,N-diethyl-2-chloroethylamine hydrochloride C0956721 869-24-9 M0131647 M0322200 T352200 N,N-diethyl-2-chloroethylamine hydrochloride 1999 08 18 M0322198 N,N-diethyl-2-chloroethylamine sulfate (1:1) C0956720 67845-39-0 M0131647 M0322198 T352198 N,N-diethyl-2-chloroethylamine sulfate (1:1) 1999 08 18 M0322199 N,N-diethyl-2-chloroethylamine sulfate (2:1) C0970543 68391-41-3 M0131647 M0322199 T352199 N,N-diethyl-2-chloroethylamine sulfate (2:1) 1999 08 18 C005437 phosphomannan 1972 01 01 1986 12 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 29 *MUCOPOLYSACCHARIDES (72-75) SUGAR PHOSPHATES (75-82) *D008351 Mannans Carbohydr Res 42(1):23;1975 J Biol Chem 253(3):647;1978 NLM RLS NLM M0046986 phosphomannan C0070885 9044-08-0 T076989 phosphomannan C113275 RNA polymerase alpha subunit 1998 07 27 2001 01 22 1999 2000 2001 2001A 2002 amino acid sequence for E. coli subunit amino-terminal domain in first source 50 *D012321 DNA-Directed RNA Polymerases Science 1998 Jul 10;281(5374):262-6 THA TWD TWD M0292613 RNA polymerase alpha subunit C0754910 EC 2.7.7.- T322618 RNA polymerase alpha subunit T322615 RNAPalpha T322616 alpha subunit, RNA polymerase T322614 RNAP alpha subunit T322617 rpoA gene product C017717 sodium thiosulfate 1978 01 01 2000 06 05 1998 1999 2000 2000A 2001 2002 do not confuse synonym sodium hyposulfite with sodium hyposulfite, synonym for di-Na salt of dithionous acid; RN given refers to thiosulfuric acid, di-Na salt 391 *SULFITES (78-80) *D013885 Thiosulfates Przegl Dermatol 66(4):375;1979 Stomatologiia (Mosk) 57(4):14;1978 NLM CCR CCR M0068706 sodium thiosulfate C0074774 thiosulfuric acid, disodium salt 7772-98-7 T121 Pharmacologic Substance T197 Inorganic Chemical D000931 Antidotes D000975 Antioxidants D000995 Antitubercular Agents D002614 Chelating Agents 10102-17-7 (pentahydrate) 31717-03-0 (unspecified Na salt) M0068706 M0313522 T098709 sodium thiosulfate Merck Index, 9th ed, p. 1122, #8468 USAN 1980, p. 298 T098708 sodium hyposulfite M0313522 pentahydrate of sodium thiosulfate C0890092 10102-17-7 T121 Pharmacologic Substance T197 Inorganic Chemical M0068706 M0313522 T343522 pentahydrate of sodium thiosulfate 1999 08 18 C013965 diolein 1977 01 01 2001 07 14 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 215 OLEIC ACIDS (77-80) *D004075 Diglycerides Nature 264(5584):361;1976 NLM TWD TWD M0062156 diolein C0058323 25637-84-7 T092159 diolein T092155 1,2-dioleoyl-rac-glycerol T092156 1,2-dioleoylglycerol T092154 1,2-DOG T092157 di-oleoylglycerol T092158 glycerol dioleate C042027 RNA I 1984 08 22 2001 01 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RNA molecule of 108 nucleotides; required for ROP inhibition of primer formation; synthesized by E coli RNA polymerase; biologically significant for plasmid replication 67 *D012329 RNA, Bacterial EMBO J 1984;3(6):1365 MEG TWD TWD M0124371 RNA I C0073424 0 T154376 RNA I T154375 RNA1 C005465 benzothiazole 1969 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 59 *D013844 Thiazoles NLM NLM M0047033 benzothiazole C0053246 95-16-9 T077036 benzothiazole C005467 chicago acid 1974 01 01 1997 08 15 1997 1998 1999 2000 2001 2002 structure 0 *D009282 Naphthalenesulfonates NLM MLH NLM M0047036 chicago acid C0602213 8-amino-1-naphthol-5,7-disulfonic acid 82-47-3 T077039 chicago acid C005470 penimepicycline 1970 01 01 1991 10 01 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *TETRACYCLINE (70-76) DRUG COMBINATIONS (73-79) *D010404 Penicillin V *D013754 Tetracyclines NLM AJC TPW M0047037 penimepicycline C0070242 4599-60-4 T077040 penimepicycline Merck Index, 9th ed, p. 920, #6894 C005481 methylene-bis-adenylic acid 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ADENINE NUCLEOTIDES (74-75) D000249 Adenosine Monophosphate *Q000031 analogs ; derivatives JNCI 60(4):789;1978 Nature (New Biol) 244(131):3;1973 NLM NLM M0047044 methylene-bis-adenylic acid C0066356 0 T077047 methylene-bis-adenylic acid C005483 pyrazolo(5-azo-1-(2-hydroxynaphthalene))-4-carboxylic acid 1973 01 01 1997 08 28 1997 1998 1999 2000 2001 2002 forms complex with Fe(3+) ions; used in determination of iron in ferrocobalt, Ascofer ; Vitaral preparations 0 AZO COMPOUNDS (73-76) NAPHTHALENES (73-75) NAPHTHOLS (73-82) *D011720 Pyrazoles Acta Pol Pharm 30(3):303;1973 NLM MLH NLM M0047046 pyrazolo(5-azo-1-(2-hydroxynaphthalene))-4-carboxylic acid C0072663 1H-Pyrazole-4-carboxylic acid, 3-((2-hydroxy-1-naphthalenyl)azo)- 29120-19-2 T077049 pyrazolo(5-azo-1-(2-hydroxynaphthalene))-4-carboxylic acid C005485 N,N-bis(methylsulfonylbutyl)amine 1973 01 01 1980 12 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 SULFONES (73-81) *D002082 Butylamines Acta Pol Pharm 30(3):261;1973 NLM BEJ NLM M0047048 N,N-bis(methylsulfonylbutyl)amine C0602215 1-Butanamine, 4-(methylsulfonyl)-N-(4-(methylsulfonyl)butyl)- 50742-35-3 T077051 N,N-bis(methylsulfonylbutyl)amine C005486 methylsulfonylbutylamine 1973 01 01 1982 09 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 SULFONES (73-82) *D002082 Butylamines Acta Pol Pharm 30(3):261;1973 NLM VSR NLM M0047049 methylsulfonylbutylamine C0602216 1-Butanamine, 4-(methylsulfonyl)-, hydrochloride 50742-34-2 T077052 methylsulfonylbutylamine C005487 4-iodoacetamidosalicylic acid 1973 01 01 1990 10 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 5 AMIDES (73-75) IODOACETATES (73-75) *D012461 Salicylic Acids D007460 Iodoacetamide *Q000031 analogs ; derivatives Biochem J 133(1):165;1973 NLM TPW NLM M0047050 4-iodoacetamidosalicylic acid C0048409 2-hydroxy-4-((iodoacetyl)amino)benzoic acid 4323-00-6 T077053 4-iodoacetamidosalicylic acid C005493 dansylbradykinin 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *BRADYKININ (74-75) DANSYL COMPOUNDS (74-76) D001920 Bradykinin *Q000031 analogs ; derivatives J Pharm Soc Jap 93(3):394;1973 NLM NLM M0047064 dansylbradykinin C0602221 49745-27-9 T077067 dansylbradykinin C035561 diarachidonyl diglyceride 1982 09 27 2001 07 14 1995 1996 1997 1998 1999 2000 2001 2001A 2002 41 *D004075 Diglycerides Biochem Biophys Res Commun 1981;100(4):1688 Mol Pharmacol 1982;21(3):688 VSR TWD TWD M0108898 diarachidonyl diglyceride C0057730 5,8,11,14-Eicosatetraenoic acid, diester with 1,2,3-propanetriol, (all-Z)- 82231-61-6 T138902 diarachidonyl diglyceride T138901 diradylglycerol T138897 1,2-sn-diradylglycerol T138898 2-arachidonyl diglyceride T138899 diarachidonin T138900 diarachidonylglycerol C038237 1-oleoyl-2-acetylglycerol 1983 06 28 2001 07 14 1995 1996 1997 1998 1999 2000 2001 2001A 2002 518 *D004075 Diglycerides J Biol Chem 1983;258(11):6701 MEG TWD TWD M0115217 1-oleoyl-2-acetylglycerol C0044555 9-Octadecenoic acid (Z)-, 2-(acetyloxy)-3-hydroxypropyl ester, (S)- 86390-77-4 T145221 1-oleoyl-2-acetylglycerol T145216 1-O-octadecenoyl-2-O-acetylglycerol T145217 1-oleoyl-2-acetyl-glycerol T145218 1-oleoyl-2-acetyl-sn-glycerol T145219 1-oleyl-2-acetylglycerol T145220 oleoylacetylglycerol C005497 3-amino-1-phenylpropylphenyl ether 1974 01 01 1982 12 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 PROPYLAMINES (74-76) *D010647 Phenyl Ethers J Pharm Soc Jap 93(4):508;1973 NLM VSR NLM M0047071 3-amino-1-phenylpropylphenyl ether C0047202 0 T077074 3-amino-1-phenylpropylphenyl ether C005500 phthalazine carbonitrile 1973 01 01 1982 09 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PYRIDAZINES (73-75) NITRILES (73-82) *D010793 Phthalazines J Pharm Soc Jpn 93(4):409;1973 NLM VSR NLM M0047075 phthalazine carbonitrile C0602228 1-Phthalazinecarbonitrile 7694-81-7 T077078 phthalazine carbonitrile C005505 toralactone 1974 01 01 1983 08 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN ; Nl from 9th CI; cpd not in Chemline 8/83; structure 1 *COUMARINS (74-80) NAPHTHOLS (74-80) PLANT EXTRACTS (74-76) *D012717 Sesquiterpenes J Pharm Soc Jpn 93(3):261;1973 NLM ACS NLM M0047082 toralactone C0206821 9,10-dihydroxy-7-methoxy-3-methyl-1H-naphtho(2,3-c)pyran-1-one 41743-74-2 T077085 toralactone C005507 polytetramethylene terephthalate 1974 01 01 1982 09 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 PHTHALIC ACIDS (74-82) *D011108 Polymers Trans Am Soc Artif Intern Organs 19(0):168;1973 NLM VSR NLM M0047086 polytetramethylene terephthalate C0084130 24968-12-5 T077089 polytetramethylene terephthalate C005508 polyalkylsulfone 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 new polymer for membrane oxygenators 0 *D011108 Polymers *D013450 Sulfones Artif Lungs Acute Resp Failure WF 668:161A:189;1975 Physiol Clin Aspects of oxygenator design WG 168 5471P:293;1975 Trans Am Soc Artif Int Organs 19(0):61;1973 NLM NLM M0047087 polyalkylsulfone C0071507 0 T077090 polyalkylsulfone C005509 4-bromo-3-(2-formamidophenyl)thiomethyl-2-methyl-1-phenyl-3-pyrazolin-5-one 1973 01 01 1980 11 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 SULFIDES (73-76) *D011720 Pyrazoles J Pharm Soc Jap 93(2):207;1973 NLM NBM NLM M0047088 4-bromo-3-(2-formamidophenyl)thiomethyl-2-methyl-1-phenyl-3-pyrazolin-5-one C0602229 0 T077091 4-bromo-3-(2-formamidophenyl)thiomethyl-2-methyl-1-phenyl-3-pyrazolin-5-one C030865 copper bis(3,5-diisopropylsalicylate) 1981 08 12 2000 05 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 copper is intricate part of molecule; not copper salt; RN given refers to cpd with specified locants for methylethyl moieties 54 *D012461 Salicylic Acids JNCI 1981;66(6):1077 RLS TWD TWD M0097402 copper bis(3,5-diisopropylsalicylate) C0056289 21246-18-4 T109 Organic Chemical T121 Pharmacologic Substance D000970 Antineoplastic Agents D007004 Hypoglycemic Agents 11112-08-6 (cpd with unspecified locants for methylethyl moieties) 57636-92-7 (SP-4-1) M0097402 M0319047 T127406 copper bis(3,5-diisopropylsalicylate) T127403 bis(3,5-diisopropylsalicylato)copper II T127400 Copper(II) diisopropylsalicylate T127401 Cu(II) 3,5-diisopropylsalicylate T127402 CuDIPS T127404 cupric bis(3,5-diisopropylsalicylate) T127405 cuprous bis(3,5-diisopropylsalicylate) M0319047 SP-4-1 of copper bis(3,5-diisopropylsalicylate) C0892013 57636-92-7 T109 Organic Chemical T121 Pharmacologic Substance M0097402 M0319047 T349047 SP-4-1 of copper bis(3,5-diisopropylsalicylate) 1999 08 18 C005513 4-O-alpha-L-sulfoiduronosyl-D-sulfoanhydromannose 1973 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *URONIC ACIDS (73-75) MANNOSE (73-75) THIOGLYCOSIDES (73-82) D007067 Iduronic Acid *Q000031 analogs ; derivatives Proc Natl Acad Sci USA 70(7):2134;1973 NLM RLS NLM M0047097 4-O-alpha-L-sulfoiduronosyl-D-sulfoanhydromannose C0602234 0 T077100 4-O-alpha-L-sulfoiduronosyl-D-sulfoanhydromannose C005516 4-(7-chloro-4-aminoquinolyl)-2-diethylaminomethyl- 5,6,7,8-tetrahydro-1-naphthol 1973 01 01 1982 09 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *QUINOLINES (73-75) NAPHTHOLS (73-82) *D000634 Aminoquinolines Experientia 28(9):1114;1972 NLM VSR NLM M0047105 4-(7-chloro-4-aminoquinolyl)-2-diethylaminomethyl- 5,6,7,8-tetrahydro-1-naphthol C0602235 37025-38-0 T077108 4-(7-chloro-4-aminoquinolyl)-2-diethylaminomethyl- 5,6,7,8-tetrahydro-1-naphthol C409766 semaphorin 5 2000 06 22 2002 01 05 2000 2001 2002 2002A member of the semaphorin family; amino acid sequence in first source 6 *D008562 Membrane Glycoproteins Mech Dev 2000 Mar 1;91(1-2):393-7 BMB THA THA M0364750 semaphorin 5 C0915062 0 T116 Amino Acid, Peptide, or Protein T417487 semaphorin 5 2000 06 22 T417491 Sema 5c 2000 06 22 T417488 semaphorin 5b 2000 06 22 T417490 semaphorin 5c 2000 06 22 T417489 semaphorin V 2000 06 22 T476025 SEMA3B 2002 01 05 T476026 LUCA-1 protein 2002 01 05 T476027 SEMA5 protein 2002 01 05 T476028 semaV protein 2002 01 05 C005522 cloxazolam 1974 01 01 1998 11 06 1999 2000 2001 2002 analog of oxazolam; structure 15 *D001568 Anti-Anxiety Agents, Benzodiazepine Chem Pharm Bull(Tokyo) 21(2):404;1973 Nervenarzt 48:351;1977 Psychopharmacology 52:17;1977 NLM BQV TPW M0047119 cloxazolam C0055964 10-chloro-2,3,5,6,7,11b-hexahydro-11b-(o- chlorophenyl)benzo(6,7)-1,4-diazepino-(5,4-b)-oxazol-6-one 24166-13-0 39287-64-4 (former CAS registry number) M0047119 M0047115 M0047119 M0047117 M0047119 M0047118 M0047119 M0309133 M0047119 M0047114 M0047119 M0047116 T077122 cloxazolam M0047115 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b(5H)-tetrahydro-oxazolo(3,2-d)(1,4)benzodiazepine-6-one C0089956 M0047119 M0047115 T077118 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b(5H)-tetrahydro-oxazolo(3,2-d)(1,4)benzodiazepine-6-one M0047117 MT 14-411 C0129209 M0047119 M0047117 T077120 MT 14-411 M0047118 Olcadil C0133781 M0047119 M0047118 T077121 Olcadil M0309133 former CAS registry number of cloxazolam C0894808 39287-64-4 M0047119 M0309133 T339133 former CAS registry number of cloxazolam 1999 08 18 M0047114 10-chloro-11b-(2-chlorophenyl)-2,3,5,6,7,11b-hexahydrobenzo(6,7)-1,4-diazepino(5,4-b)oxazol-6-one C0089955 M0047119 M0047114 T077117 10-chloro-11b-(2-chlorophenyl)-2,3,5,6,7,11b-hexahydrobenzo(6,7)-1,4-diazepino(5,4-b)oxazol-6-one M0047116 CS 370 C0111145 M0047119 M0047116 T077119 CS 370 C015586 propiverine 1978 01 01 2000 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2000B 2001 2002 structure 83 *D001561 Benzilates Psychiat Neurol Med Psychol 20(21):77;1975 NLM CCR CCR M0064951 propiverine C0138666 60569-19-9 T109 Organic Chemical T121 Pharmacologic Substance D000978 Antiparkinson Agents D002121 Calcium Channel Blockers D010276 Parasympatholytics 54556-98-8 (HCl) M0064951 M0064953 M0064951 M0312891 T094954 propiverine T094952 alpha-diphenyl alpha-n-propoxyacetic acid-4(1-methylpiperidyl)ester T094953 propiverin M0064953 Mictonorm C0066526 T109 Organic Chemical T121 Pharmacologic Substance M0064951 M0064953 T094956 Mictonorm M0312891 propiverine hydrochloride C0138667 54556-98-8 T109 Organic Chemical T121 Pharmacologic Substance M0064951 M0312891 T094955 propiverine hydrochloride C005527 methyl-5-iodopyridine-2-carboximidate 1973 01 01 1997 08 19 1997 1998 1999 2000 2001 2002 reagent used to introduce heavy atoms into specific sites in proteins; structure 0 *PYRIDINES (73-82) IMINES (73-80) IODINE (73-76) *D007096 Imidoesters Biochem J 131(4):625;1973 NLM MLH NLM M0047127 methyl-5-iodopyridine-2-carboximidate C0602241 2-Pyridinecarboximidic acid, 5-iodo-, methyl ester 41960-48-9 T077130 methyl-5-iodopyridine-2-carboximidate C020785 octene-1,2-oxide 1979 01 01 2000 09 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 1 EPOXY COMPOUNDS (79-82) *D000475 Alkenes Chem Biol Interact 25(2-3):321;1979 NLM TWD TWD M0074895 octene-1,2-oxide C0069350 hexyloxirane 2984-50-1 T109 Organic Chemical T104898 octene-1,2-oxide C005533 4-hydroxylaminobenzenesulfonamide 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 HYDROXYLAMINES (74-76) *D013424 Sulfanilamides Chem Pharm Bull (Tokyo) 21(4):757;1973 J Dermatol 1(3):99;1974 NLM NLM M0047133 4-hydroxylaminobenzenesulfonamide C0048355 4-(hydroxyamino)benzenesulfonamide 877-67-8 T077136 4-hydroxylaminobenzenesulfonamide C115299 LERK-7 protein 1998 11 13 1998 11 13 1999 2000 2001 2002 ligand of the Eph-related kinases; amino acid sequence in first source; GenBank U26403 1 *D014157 Transcription Factors Cytokine 1997 Aug;9(8):540-9 BVL BVL BVL M0296963 LERK-7 protein CT276774 0 M0296963 M0296961 M0296963 M0296962 T326968 LERK-7 protein M0296961 AL-1 protein CT276772 M0296963 M0296961 T326966 AL-1 protein M0296962 REK7 ligand AL-1 CT276773 M0296963 M0296962 T326967 REK7 ligand AL-1 C005535 3-(3-oxo-17 beta-hydroxy-13-ethylgon-4-en-17 alpha-yl)propionic acid gamma-lactone 1973 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *LACTONES (73-75) KETOSTEROIDS (75-76) *D006067 Gonanes J Pharm Soc Jpn 93(2):246;1973 NLM NLM M0047136 3-(3-oxo-17 beta-hydroxy-13-ethylgon-4-en-17 alpha-yl)propionic acid gamma-lactone C0602244 0 T077139 3-(3-oxo-17 beta-hydroxy-13-ethylgon-4-en-17 alpha-yl)propionic acid gamma-lactone C005536 2-methylisoborneol 1974 01 01 1987 01 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 14 ALCOHOLS (74-76) *D001892 Bornanes D009812 Odors CRC Crit Rev Microbiol 1979;7(3):191 Yakugaku Zasshi 93(5):658;1973 Yakugaku Zasshi 98(1):124;1978 NLM PEH NLM M0047137 2-methylisoborneol C0046386 2371-42-8 T077140 2-methylisoborneol C005545 2-acetyl-4-((3-dimethylamino)propyl)-3,4-dihydro-3- phenyl-2H-1,4-benzothiazine 1973 01 01 1986 08 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D013843 Thiazines J Med Chem 16(7):780;1973 NLM THA NLM M0047156 2-acetyl-4-((3-dimethylamino)propyl)-3,4-dihydro-3- phenyl-2H-1,4-benzothiazine C0602257 42583-66-4 T077159 2-acetyl-4-((3-dimethylamino)propyl)-3,4-dihydro-3- phenyl-2H-1,4-benzothiazine C115304 ephrin-A5 1998 11 13 2001 12 31 1999 2000 2001 2002 2002A transmembrane ligand of Eph-related kinases 52 *D008565 Membrane Proteins Mol Cell Neurosci 1997;9(4):314-28 BVL CCR CCR M0296978 ephrin-A5 CT276789 0 T116 Amino Acid, Peptide, or Protein M0296978 M0296977 T326983 ephrin-A5 T326981 AL-1 M0296977 RAGS protein CT276788 T116 Amino Acid, Peptide, or Protein M0296978 M0296977 T326982 RAGS protein C063504 KAR3 protein 1990 05 01 2001 01 26 1995 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 amino acid sequence given in first source; member of a family of kinesin-like proteins characterized by the presence of the mechanochemical domain tethered to different protein binding domains 26 *D005656 Fungal Proteins D008869 Microtubule-Associated Proteins D016547 Kinesin Cel 1990;60(6):1029 TPW WXM WXM M0175265 KAR3 protein C0083119 0 T205270 KAR3 protein T205269 KAR3 gene product C069492 2-chain anabolic protein 1991 07 29 2001 01 26 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source; modified two-chain form of biosynthetic hGH which lacks amino acids 1-8 ; 135-145 1 *D010446 Peptide Fragments D013006 Growth Hormone *Q000031 analogs ; derivatives Endocrinology 1991;1(129):465 TPW WXM WXM M0189647 2-chain anabolic protein C0646456 139691-12-6 T219652 2-chain anabolic protein T219651 2-CAP C002477 nicotinuric acid 1973 01 01 2001 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd 10 *URIC ACID (73-75) GLYCINE/*analogs (73-82) URIC ACID/*analogs (75-77) *D009539 Nicotinic Acids Clin Chem 24(10):1740;1978 J Biol Chem 247(24):8023;1972 NLM TWD TWD M0043075 nicotinuric acid C0068730 583-08-4 16277-64-8 (mono-Na salt) M0043075 M0307967 T073078 nicotinuric acid M0307967 nicotinuric acid, monosodium salt C0951119 16277-64-8 M0043075 M0307967 T337967 nicotinuric acid, monosodium salt 1999 08 18 C069514 MAP4 1991 07 29 2001 01 26 1996 1997 1998 1999 2000 2001 2001A 2002 partial amino acid sequence given in first source 54 *D008869 Microtubule-Associated Proteins J Cell Sci 1991;98(Pt 1):27 KLN WXM WXM M0189695 MAP4 C0127014 0 T219700 MAP4 T219699 microtubule associated protein 4 C005558 Ro 3-3528 1968 01 01 1994 09 19 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D001572 Benzofurans *D004983 Ethanolamines NLM PML TPW M0047184 Ro 3-3528 C0073517 6,7-dimethyl-alpha-(isopropylaminomethyl)-2- benzofuranmethanol 14047-00-8 T077187 Ro 3-3528 C409765 Nkx-2.10 protein 2000 06 22 2000 06 22 2000 2000A 2001 2002 amino acid sequence in first source; GenBank AF127224 1 *D014157 Transcription Factors *D018398 Homeodomain Proteins Mech Dev 2000 Mar 1;91(1-2):369-73 BMB BMB BMB M0364740 Nkx-2.10 protein C0915061 0 T116 Amino Acid, Peptide, or Protein T417480 Nkx-2.10 protein 2000 06 22 T417481 Nkx 2-10 protein 2000 06 22 T417482 XNkx2-10 gene product 2000 06 22 T417483 Nkx2-10 protein 2000 06 22 C081587 strontium ranelate 1993 07 08 2002 01 07 1999 2000 2001 2001A 2001B 2002 2002A 2002B an uncoupling agent containing strontium prevents bone loss by depressing bone resorption ; maintaining bone formation in estrogen-deficient rats 9 *D009942 Organometallic Compounds *D013876 Thiophenes J Bone Miner Res 1993 May;8(5):607-15 RLS TWD TWD M0384217 strontium ranelate C0936139 0 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0384217 M0217578 M0384217 M0217581 T443189 strontium ranelate 2001 04 17 M0217578 3-(3-cyano-4-carboxymethyl-5-carboxy-2-thienyl)-3-azapentanedioic distrontium salt C0527653 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0384217 M0217578 T247583 3-(3-cyano-4-carboxymethyl-5-carboxy-2-thienyl)-3-azapentanedioic distrontium salt M0217581 S 12911 C0527655 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0384217 M0217581 T247586 S 12911 T247584 S-12911 T247585 S12911 C089143 ephrin-B1 1994 09 28 2001 08 07 1999 2000 2001 2001A 2002 LERK - Ligand for Eph-Related Kinases; similar to LERK-1 (B61); amino acid sequence in first source 72 *PROTEINS (94-97) *D008565 Membrane Proteins EMBO J 1994 Aug 15;13(16):3757-62 BMB jmp jmp M0235725 ephrin-B1 C0662925 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T265728 ephrin-B1 T265721 Cek5 RPTK ligand T265722 Cek5 ligand T265723 EFNB1 gene product T265730 LERK-2 protein T265724 Elk-L protein T265725 Eph family receptor interacting protein B1 T265727 elk ligand C005649 GP 48989 1974 01 01 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 HYDRAZONES (74-76) *D013844 Thiazoles Experientia 29(7):823;1973 Oncology 33:229;1976 NLM TWD TWD M0047313 GP 48989 C0061839 5-methyl-3-(2-methylallyl)-2-((3-methyl-4-oxo- 2-thiazolidinylidene)hydrazono)-4-thiazolidinone 31209-24-2 T077316 GP 48989 T077315 GP-48989 C007012 4-chloronorpseudoephedrine 1974 01 01 2001 01 30 1998 1999 2000 2001 2001A 2002 (cis)-isomer of 4-chloronorephedrine; structure; RN given refers to (S-(R*R*))-isomer 0 *PHENETHYLAMINES (74-75) *PROPANOLAMINES (74-75) SEROTONIN/*antag (75-78) D010665 Phenylpropanolamine *Q000031 analogs ; derivatives J Med Chem 17(4):416;1974 NLM TWD TWD M0049905 4-chloronorpseudoephedrine C0602955 Benzenemethanol, alpha-(1-aminoethyl)-4-chloro-, hydrochloride, (S-(R*,R*))- 52373-27-0 T079908 4-chloronorpseudoephedrine T079907 p-chloronorpseudoephedrine C005612 Ro 2-7239 1970 01 01 1978 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ANDROGENS *antagonists (70-78) *D010616 Phenanthrenes NLM NLM M0047258 Ro 2-7239 C0602260 7-acetyl-4,4a,4b,5,6,7,8,8a,9,10-decahydro-2(3H)- phenanthrone 2327-61-9 T077261 Ro 2-7239 C050557 tauropine 1986 12 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given from CA Index Guide 1985; RN not in Chemline 12/86 5 *D000603 Amino Acids, Sulfur Eur J Biochem 1986;160(2):311 MEG CCR CCR M0144294 tauropine C0075855 33497-79-9 T174299 tauropine T174297 N-(1-carboxyethyl)taurine T174298 rhodoic acid C005620 quinbolone 1974 01 01 1998 07 21 1998 1999 2000 2001 2002 structure 2 *ANDROSTENES (74-75) CYCLOPENTANES (74-76) KETOSTEROIDS (74-76) *D000730 Androstadienes J Allergy Clin Immunol 1980;65(1):75 Minerva Med 68(32):2245;1977 NLM BQV NLM M0047267 quinbolone C0072862 17 beta-(1-cyclopenten-1-yloxy)androsta-1,4- dien-3-one 2487-63-0 T077270 quinbolone Merck 9th ed, p. 1046, #7841 Negwer #4327 C007016 chlorophenol red 1974 01 01 2001 01 30 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 used in transport studies of goldfish renal tubules; structure 12 *PHENOLPHTHALEINS (74-75) CHLORINE (74-79) D010637 Phenolsulfonphthalein *Q000031 analogs ; derivatives Biochemistry 14(11):2317;1975 Bull Environ Contam Toxicol 10(3):181;1973 J Exp Zool 199(3):449;1977 Toxicol Appl Pharmacol 38(3):621;1976 NLM TWD TWD M0049910 chlorophenol red C0055430 3',3''-dichlorophenolsulfonphthalein 4430-20-0 27459-85-4 (former CAS registry number) T079913 chlorophenol red C005680 bietamiverine 1970 01 01 2001 07 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 0 *PHENYLACETATES (72-75) DIETHYLAMINES (74-75) *D010880 Piperidines Sov Med 2:104;1977 NLM TWD TWD M0047369 bietamiverine C0602297 479-81-2 1477-10-7 (mono-HCl) M0047369 M0309200 M0047369 M0047368 T077372 bietamiverine T077370 alpha-phenyl-1-piperidineacetic acid-2-diethylaminoethyl ester M0309200 bietamiverine monohydrochloride C0951405 1477-10-7 M0047369 M0309200 T339200 bietamiverine monohydrochloride 1999 08 18 M0047368 Spasmaparid C0602296 M0047369 M0047368 T077371 Spasmaparid C032269 sialyl-N-acetyllactosamine 1981 12 07 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from urine of systemic lupus erythematosus patients 12 *D000606 Amino Sugars Arthritis Rheum 1981;24(9):1137 MEG CCR CCR M0100843 sialyl-N-acetyllactosamine C0074486 0 M0100843 M0100842 T130847 sialyl-N-acetyllactosamine T130845 SNALA M0100842 sialyl(2-3)(6)N-acetyllactosamine C0142263 M0100843 M0100842 T130846 sialyl(2-3)(6)N-acetyllactosamine C007018 4-chlorophenoxysalicylic acid 1974 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 *D012461 Salicylic Acids Acta Univ Carol(Med Monogr) 52(0):33;1972 NLM TWD TWD M0049916 4-chlorophenoxysalicylic acid C0602959 0 T079919 4-chlorophenoxysalicylic acid T079918 p-chlorophenoxysalicylic acid C007024 chloro-(tetra-4-methylphenylporphinato)indium(III) 1974 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 *INDIUM (74-82) *D011166 Porphyrins J Pharm Sci 62(9):1574;1973 NLM TWD TWD M0049938 chloro-(tetra-4-methylphenylporphinato)indium(III) C0602962 Indium, chloro(5,10,15,20-tetrakis(4-methylphenyl)-21H,23H-porphinato(2-)-N(21),N(22),N(23),N(24))-, (SP-5-12)- 65139-92-6 T079941 chloro-(tetra-4-methylphenylporphinato)indium(III) T079940 chloro-(tetra-p-methylphenylporphinato)indium(III) C431669 merozoite surface protein 8, Plasmodium 2001 07 31 2001 2002 amino acid sequence in first source 1 *D000953 Antigens, Protozoan *D015800 Protozoan Proteins Mol Biochem Parasitol 2001 May;114(2):217-26 BMB BMB M0394509 merozoite surface protein 8, Plasmodium C0968134 0 T116 Amino Acid, Peptide, or Protein T129 Immunologic Factor T455849 merozoite surface protein 8, Plasmodium 2001 07 31 T455850 Plasmodium MSP8 2001 07 31 C005645 cobalt(II) mesoporphyrin IX dimethyl ester 1974 01 01 1983 07 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PORPHYRINS (74-75) COBALT (74-82) *D008652 Mesoporphyrins J Am Chem Soc 95(14):4545;1973 NLM DLJ NLM M0047309 cobalt(II) mesoporphyrin IX dimethyl ester C0056028 19630-46-7 T077312 cobalt(II) mesoporphyrin IX dimethyl ester C005646 nickel(II) mesoporphirin IX dimethyl ester 1974 01 01 1982 09 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PORPHYRINS (74-75) NICKEL (74-75) ORGANOMETALLIC COMPOUNDS (74-82) *D008652 Mesoporphyrins J Am Chem Soc 95(14):4545;1973 NLM VSR NLM M0047310 nickel(II) mesoporphirin IX dimethyl ester C0602276 Nickel, (dimethyl 7,12-diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(2-)-N21,N22,N23,N24)-, (SP-4-2)- 15892-09-8 T077313 nickel(II) mesoporphirin IX dimethyl ester C419142 thiazin red 2001 01 30 2001 2002 has affinity for fibrillary structures such as neurofibrillary tangles or senile plaques 4 *D005456 Fluorescent Dyes Acta Neuropathol (Berl). 2000 Oct;100(4):385-9 BMB BMB M0377490 thiazin red C0963609 0 T130 Indicator, Reagent, or Diagnostic Aid T434587 thiazin red 2001 01 30 C005650 ivosin 1974 01 01 1982 08 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains a copolymerizate of p-divinyl benzene ; dimethylaminomethylstyrene 0 *VINYL COMPOUNDS (74-76) DRUG COMBINATIONS (74-76) *D011145 Polyvinyls *D013343 Styrenes D007475 Ion Exchange Resins D009824 Ointments Dermatologica 145(3):176;1972 Przg Dermatol 6:167;1976 NLM VSR NLM M0047314 ivosin C0064124 N,N-dimethyl-4-(1-methylethenyl)benzenamine polymer with 1,4-diethenylbenzene hydrochloride 38548-13-9 T077317 ivosin C005651 indulona 1974 01 01 1991 07 10 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains salts of EDTA ; ascorbic acid 0 *D001205 Ascorbic Acid *D004492 Edetic Acid D004338 Drug Combinations D009824 Ointments Dermatologica 145(3):1175;1972 NLM IDX TPW M0047315 indulona C0602278 L-ascorbic acid mixt. with disodium ((N,N'-1,2- ethanediylbis(N-carboxymethyl)glycinato))(4-)- N,N',O,O',O(N),O(N'))calciate(2-) ; N,N'-1,2- ethanediylbis(N-(carboxymethyl)glycine) disodium salt 37270-70-5 T077318 indulona C005652 disparalone 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ALKENES (74-76) *D005233 Fatty Alcohols Experientia 29(7):783;1973 NLM NLM M0047316 disparalone C0602279 7-oxo-10-hexadecen-1-ol 49831-68-7 T077319 disparalone C043506 N-acetyl-3-O-methyllactosamine 1984 12 12 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 2 *D000606 Amino Sugars Carbohydr Res 1984;132(1):119 DLJ CCR CCR M0128008 N-acetyl-3-O-methyllactosamine C0067630 0 T158013 N-acetyl-3-O-methyllactosamine T158011 2-acetamido-2-deoxy-4-O-beta-D-galactopyranosyl-3-O-methyl-D-glucopyranose T158012 Ac-MeLac C456339 cytokine receptor, GLM-R 2002 06 12 2002 a type I cytokine receptor with homology to the interleukin-6 receptor signal transducing chain, gp130, and granulocyte colony-stimulating factor receptor; human and murine GLM-R cDNAs encode open reading frames of 732 and 716 amino acids, respectively, and the corresponding genes are located in close proximity to gp130 genes on human chromosome 5 and mouse chromosome 13; amino acid sequence in first source 1 *D018121 Receptors, Cytokine J Biol Chem 2002 May 10;277(19):16831-6 BMB BMB M0426769 cytokine receptor, GLM-R 0 T192 Receptor M0426769 M0426770 M0426769 M0426771 T498142 cytokine receptor, GLM-R 2002 06 12 T498143 GLM-R 2002 06 12 T498144 gp130-like monocyte receptor 2002 06 12 M0426770 GLM-R, human T192 Receptor M0426769 M0426770 T498145 GLM-R, human 2002 06 12 M0426771 GLM-R, mouse T192 Receptor M0426769 M0426771 T498146 GLM-R, mouse 2002 06 12 C007033 chlortoluron 1974 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 26 CHLOROBENZENES (74-82) *D010671 Phenylurea Compounds J Food Agric Chem 24(4):759;1976 Rocz Panstw Zakl Hig 25(1):123;1974 NLM TWD TWD M0049959 chlortoluron C0055480 N'-(3-chloro-4-methylphenyl)-N,N-dimethylurea 15545-48-9 D006543 Herbicides, Urea T079962 chlortoluron T079961 chlorotoluron C005664 2,16 alpha-dihydroxyestrone 3-methyl ether 1974 01 01 1977 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ESTRANES (74-75) ESTRONE/*analogs (75-77) METHYL ETHERS (74-76) *D006894 Hydroxyestrones Chem Pharm Bull (Tokyo) 21(4):914;1973 Chem Pharm Bull (Tokyo) 23(7):1613;1975 NLM NLM M0047339 2,16 alpha-dihydroxyestrone 3-methyl ether C0045234 42241-06-5 T077342 2,16 alpha-dihydroxyestrone 3-methyl ether C005665 uridine 5'-(alpha-D-apio-D-furanosyl pyrophosphate) 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 PENTOSES (74-76) PYROPHOSPHORIC ACIDS (74-75) *D014539 Uridine Diphosphate Sugars Biochem J 133(2):227;1973 NLM NLM M0047340 uridine 5'-(alpha-D-apio-D-furanosyl pyrophosphate) C0602292 uridine 5'-(trihydrogen diphosphate), mono-D- apio-D-furanosyl ester 20230-91-5 T077343 uridine 5'-(alpha-D-apio-D-furanosyl pyrophosphate) C007034 chlorzymine 1974 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 0 ALKYNES (74-82) *D001596 Benzylamines Farmakol Toksikol 36(5):548;1973 NLM TWD TWD M0049960 chlorzymine C0602964 2-chloro-N-methyl-N-(2-propynyl)benzenemethanamine 2520-91-4 5220-94-0 (HCl) M0049960 M0309805 T079963 chlorzymine M0309805 chlorzymine hydrochloride C0951595 5220-94-0 M0049960 M0309805 T339805 chlorzymine hydrochloride 1999 08 18 C005669 11 alpha-bromoacetoxyprogesterone 1974 01 01 1997 01 02 1997 1998 1999 2000 2001 2002 6 *PREGNENEDIONES (74-75) STEROIDS, BROMINATED (75-81) *D006908 Hydroxyprogesterones J Biol Chem 248(16):5641;1973 J Biol Chem 250(19):7656;1975 NLM MLH NLM M0047346 11 alpha-bromoacetoxyprogesterone C0044704 36049-50-0 T077349 11 alpha-bromoacetoxyprogesterone C084030 EXP 631 1993 12 03 2001 07 31 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a centrally-acting non-opioid analgesic; exhibits serotonin and norepinephrine reuptake inhibiting activities; structure given in first source 1 *D010880 Piperidines *D013876 Thiophenes Biopharm Drug Dispos 1993 Aug;14(6):519-31 PML TWD TWD M0223411 EXP 631 C0662190 4-Piperidinemethanol, alpha,alpha,1-trimethyl-4-(3-thienyl)-, (Z)-2-butenedioate (2:1) (salt) 151656-58-5 M0223411 M0223408 T253416 EXP 631 T253414 EXP-631 T253415 EXP631 M0223408 4-(3-thienyl)-alpha,alpha,1-trimethyl-4-piperidinemethanol hemi-fumarate salt C0662187 M0223411 M0223408 T253413 4-(3-thienyl)-alpha,alpha,1-trimethyl-4-piperidinemethanol hemi-fumarate salt C431670 3-amino-1,2,4-benzotriazine 4-oxide 2001 07 31 2001 07 31 2001 2001A 2002 structure in first source 1 *D014227 Triazines J Org Chem 2001 Jan 12;66(1):107-14 SZM SZM SZM M0394510 3-amino-1,2,4-benzotriazine 4-oxide C0968135 0 T109 Organic Chemical T455851 3-amino-1,2,4-benzotriazine 4-oxide 2001 07 31 T455852 3-A-BTAO 2001 07 31 C031432 sarmoxicillin 1981 09 15 2000 12 27 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 methoxymethyl ester of hetamoxicillin; RN refers to ((2S-(2alpha,5alpha,6beta))-isomer) 1 D000658 Amoxicillin *Q000031 analogs ; derivatives Antimicrob Agents Chemother 1981;19(6):1004 RLS WXM WXM M0098756 sarmoxicillin C0614192 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(4-(4-hydroxyphenyl)-2,2-dimethyl-5-oxo-1-imidazolidinyl)-3,3-dimethyl-7-oxo-, methoxymethyl ester, (2S-(2alpha,5alpha,6beta))- 67337-44-4 T109 Organic Chemical T195 Antibiotic 60903-19-7 (mono HCl((2S-(2alpha,5alpha,6beta(S*)))-isomer) 60903-21-1 ((2S-(2alpha,5alpha,6beta(S*)))-isomer) M0098756 M0319259 M0098756 M0319258 T128760 sarmoxicillin USAN (1979) M0319259 sarmoxicillin, (2S-(2alpha,5alpha,6beta(S*)))-isomer C0955181 60903-21-1 T109 Organic Chemical T195 Antibiotic M0098756 M0319259 T349259 sarmoxicillin, (2S-(2alpha,5alpha,6beta(S*)))-isomer 1999 08 18 M0319258 sarmoxicillin monohydrochloride, (2S-(2alpha,5alpha,6beta(S*)))-isomer C0955180 60903-19-7 T109 Organic Chemical T195 Antibiotic M0098756 M0319258 T349258 sarmoxicillin monohydrochloride, (2S-(2alpha,5alpha,6beta(S*)))-isomer 1999 08 18 C031464 CF 19415 1981 09 22 2000 12 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 RN given refers to cpd without isomeric designation 1 *D000097 Acetonitriles J Pharm Pharmacol 1981;33(6):348 RLS WXM WXM M0098838 CF 19415 C0614211 Pyrazineacetonitrile, alpha-(methoxyimino)- 79378-26-0 T109 Organic Chemical T121 Pharmacologic Substance 67936-63-4 ((Z)-isomer) 67936-76-9 ((E)-isomer) M0098838 M0098837 M0098838 M0319269 M0098838 M0319268 T128842 CF 19415 M0098837 2-alpha-methoxyiminopyrazine acetonitrile C0614210 T109 Organic Chemical T121 Pharmacologic Substance M0098838 M0098837 T128841 2-alpha-methoxyiminopyrazine acetonitrile M0319269 CF 19415, (E)-isomer C0892075 67936-76-9 T109 Organic Chemical T121 Pharmacologic Substance M0098838 M0319269 T349269 CF 19415, (E)-isomer 1999 08 18 M0319268 CF 19415, (Z)-isomer C0892074 67936-63-4 T109 Organic Chemical T121 Pharmacologic Substance M0098838 M0319268 T349268 CF 19415, (Z)-isomer 1999 08 18 C005843 resazurin 1973 01 01 2001 01 19 1997 1998 1999 2000 2001 2001A 2002 used as indicator in detection of hyposulfite (sulfoxylate); in food research (reductase test); structure 58 CYCLIC N-OXIDES (74-76) *D010078 Oxazines Biochim Biophys Acta 484(2):249;1977 J Dairy Sci 61(5):592;1978 Veterinariia 10:78;1976 NLM CCR CCR M0047646 resazurin C0073080 7-hydroxy-3H-phenoxazin-3-one 10-oxide 550-82-3 D007202 Indicators and Reagents T077649 resazurin Merck Index, 9th ed, p. 1056, #7933 T077646 diazoresorcinol T077647 reazurin T077648 reazurine C005832 thiopurinol 1972 01 01 2000 09 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 4-thio analog of allopurinol; structure 13 *PYRIMIDINES (72-75) PYRAZOLES (72-75) SULFHYDRYL COMPOUNDS (72-76) D000493 Allopurinol *Q000031 analogs ; derivatives Acta Med Austriaca 3(3):91;1976 Ann Med Internel 127(8-9):596;1976 Ann Rheum Dis 33(6):548;1974 Sem Hop Ther 53(5-6):321;1977 Verh Dtsch Ges Inn Med 81:1462;1975 NLM CCR CCR M0047625 thiopurinol C0076516 5334-23-6 T109 Organic Chemical T121 Pharmacologic Substance T077628 thiopurinol T077626 4-mercaptopyrazolo(3,4-d)pyrimidine T077627 tisopurine C005711 fenpiverinium 1970 01 01 1998 05 20 1998 1999 2000 2001 2002 RN given refers to bromide; structure 5 AMIDES (74-76) *D010880 Piperidines NLM BQV NLM M0047448 fenpiverinium C0060190 1-(3-carbamoyl-3,3-diphenylpropyl)-1-methylpiperidinium bromide 125-60-0 M0047448 M0047447 M0047448 M0047445 M0047448 M0047446 T077451 fenpiverinium Merck Index, 9th ed, p. 521, #3915 M0047447 resantin C0140232 M0047448 M0047447 T077450 resantin M0047445 fenpipramide methobromide C0117476 M0047448 M0047445 T077448 fenpipramide methobromide M0047446 fenpiverinium bromide C0117477 M0047448 M0047446 T077449 fenpiverinium bromide C090248 LF 7-0156 1994 12 02 2001 01 19 1995 1996 1997 1998 1999 2000 2001 2001A 2001B 2002 a nonpeptide antagonist radioligand for the type 1 angiotensin II receptor; structure given in first source 2 *D001565 Benzoates *D007093 Imidazoles Mol Pharmacol 1994 Oct;46(4):693-701 PML CCR CCR M0238497 LF 7-0156 C0290429 0 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0238497 M0238495 T268502 LF 7-0156 T268501 LF-7-0156 M0238495 2-(((2-butyl-1-((4-carboxyphenyl)methyl)-1H-imidazol-5-yl)methyl)amino)benzoic acid C0290428 T109 Organic Chemical T121 Pharmacologic Substance T130 Indicator, Reagent, or Diagnostic Aid M0238497 M0238495 T268500 2-(((2-butyl-1-((4-carboxyphenyl)methyl)-1H-imidazol-5-yl)methyl)amino)benzoic acid C103003 S100P protein 1997 01 21 2001 02 23 1997 1998 1999 2000 2001 2001A 2002 an androgen-regulated gene product, may be involved in the etiology of prostate cancer; amino acid sequence given in first source 9 *D002135 Calcium-Binding Proteins Prostate 1996 Dec;29(6):350-5 BMB WXM WXM M0269450 S100P protein C0532956 0 T299455 S100P protein T299454 S100P gene product C103005 SPR28 protein 1997 01 21 2001 02 23 1997 1998 1999 2000 2001 2001A 2002 a septin isolated from Saccharomyces cerevisiae; SPR - SPorulation Regulated; MW 48.2 kDa; has 423 amino acid residues; amino acid sequence given in first source; GenBank Z48612 1 *D005656 Fungal Proteins *D018797 Cell Cycle Proteins Microbiology 1996 Oct;142(Pt 10):2897-905 PML WXM WXM M0269454 SPR28 protein C0532960 0 T299459 SPR28 protein T299458 Spr28 gene product C103072 HAM-1 protein, Caenorhabditis 1997 01 22 2001 02 23 1997 1998 1999 2000 2001 2001A 2002 asymmetric distribution of protein in neuroblasts enables daughter cells to adopt distinct fates; amino acid sequence given in first source 2 *D009419 Nerve Tissue Proteins D015801 Helminth Proteins Development 1996 Nov;122(11):3509-18 BMB WXM WXM M0269587 HAM-1 protein, Caenorhabditis C0533083 0 T299592 HAM-1 protein, Caenorhabditis T299591 ham-1 gene product, C. elegans C412833 Slm9 protein 2000 09 07 2000 2001 2002 involved in mitotic control; isolated from Schizosaccharomyes pombe; amino acid sequence in first source; GenBank AL031349 1 *D009687 Nuclear Proteins *D018797 Cell Cycle Proteins Genetics 2000 Jun;155(2):623-31 THA THA M0369071 Slm9 protein C0960507 0 T116 Amino Acid, Peptide, or Protein T423389 Slm9 protein 2000 09 07 T423390 slm9 gene product 2000 09 07 C005753 ethyl 6-chlorochroman-2-carboxylate 1974 01 01 1981 06 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 chroman analog of clofibrate; structure 1 *BENZOPYRANS (74-75) CARBOXYLIC ACIDS (74-76) *D002839 Chromans Lipids 8(7):378;1973 NLM RLS NLM M0047507 ethyl 6-chlorochroman-2-carboxylate C0059746 6-chloro-2-chromancarboxylic acid ethyl ester 33533-96-9 T077510 ethyl 6-chlorochroman-2-carboxylate C005754 ethyl 2,3-dihydrobenzofuran-2-carboxylate 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 dihydrobenzofuran analog of clofibrate; structure 0 CARBOXYLIC ACIDS (74-76) *D001572 Benzofurans Lipids 8(7):378;1973 NLM NLM M0047508 ethyl 2,3-dihydrobenzofuran-2-carboxylate C0602305 43119-53-5 T077511 ethyl 2,3-dihydrobenzofuran-2-carboxylate C005755 ethyl 1,4-benzodioxane-2-carboxylate 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *DIOXINS (74-75) CARBOXYLIC ACIDS (74-76) *D004146 Dioxanes Lipids 8(7):378;1973 NLM NLM M0047509 ethyl 1,4-benzodioxane-2-carboxylate C0602306 4739-94-0 T077512 ethyl 1,4-benzodioxane-2-carboxylate C086474 SRS4 protein 1994 04 25 2001 08 15 1998 1999 2000 2000A 2001 2001A 2002 the small subunit of ribulose-1,5-bisphosphate; has been sequenced 16 *D012273 Ribulose-Bisphosphate Carboxylase Mol Cell Biol 1994 Apr;14(4):2640-50 THA CCR CCR M0229247 SRS4 protein C0253179 0 T259252 SRS4 protein T259250 SRS4 gene product T259251 rbcS gene product T423395 rbcS protein 2000 09 07 C005762 7-oxo-7H-benzo(d,e)pyrrolo(1,2-a)quinoline 1974 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 PYRROLES (74-82) *D011804 Quinolines Farmaco (Sci) 27(9):786;1972 NLM VSR NLM M0047527 7-oxo-7H-benzo(d,e)pyrrolo(1,2-a)quinoline C0602314 0 T077530 7-oxo-7H-benzo(d,e)pyrrolo(1,2-a)quinoline C005763 11-oxo-11H-benzo(e)pyrrolo(1,2-a)indole 1974 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 PYRROLES (74-82) *D007211 Indoles Farmaco (Sci) 27(9):786;1972 NLM VSR NLM M0047528 11-oxo-11H-benzo(e)pyrrolo(1,2-a)indole C0602315 11H-Benzo(e)pyrrolo(1,2-a)indol-11-one 38040-61-8 T077531 11-oxo-11H-benzo(e)pyrrolo(1,2-a)indole C410824 GP73 protein 2000 07 19 2001 08 15 2000 2001 2001A 2002 a Golgi-localized protein upregulated by viral infection; amino acid sequence in first source; GenBank AF236056 2 *D008565 Membrane Proteins D006056 Golgi Apparatus Gene 2000 May 16;249(1-2):53-65 SZM TWD TWD M0366175 GP73 protein C0915696 0 T116 Amino Acid, Peptide, or Protein T419333 GP73 protein 2000 07 19 T419334 GP73 gene product 2000 07 19 C005771 4',5'-dihydropsoralen 1975 01 01 1982 11 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 *FICUSIN/analogs (75-79) *D011564 Psoralens Can J Biochem 51(7):965;1973 NLM VSR NLM M0047539 4',5'-dihydropsoralen C0047745 7535-48-0 T077542 4',5'-dihydropsoralen C005773 N(6)-(3-hydroxy-3-methylbutyl)adenine 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 substrate for xanthine oxidase 0 *ADENINE (74-75) ALCOHOLS, AMYL (74-76) D000225 Adenine *Q000031 analogs ; derivatives Can J Biochem 51(7):1123;1973 NLM NLM M0047540 N(6)-(3-hydroxy-3-methylbutyl)adenine C0602319 2-methyl-4-(1H-purin-6-ylamino)-2-butanol 16412-36-5 T077543 N(6)-(3-hydroxy-3-methylbutyl)adenine C005786 teflurane 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 ETHANE (74-76) *D006846 Hydrocarbons, Halogenated NLM NLM M0047549 teflurane C0076042 2-bromo-1,1,1,2-tetrafluoroethane 124-72-1 T077552 teflurane Merck Index, 9th ed, #8861 Negwer, 5th ed, #25 USAN 1980, p. 314 C005792 thiopyronine 1974 01 01 1997 08 28 1997 1998 1999 2000 2001 2002 RN in Chemline for cpd with ZnCl4: 52171-29-6 13 *THIOXANTHENES (74-79) AMMONIUM COMPOUNDS (74-79) D011754 Pyronine *Q000031 analogs ; derivatives Int J Radiat Biol 31(1):35;1977 Int J Radiat Biol 31(2):113;1977 Int J Radiat Biol 34(3):213;1978 Photochem Photobiol 28(3):331;1978 Photochem Photobiol 29(6):1199;1979 NLM MLH NLM M0047554 thiopyronine C0076519 N-(6-(dimethylamino)-3H-thioxanthen-3-ylidene)-N-methylmethanaminium, chloride 2412-14-8 T077557 thiopyronine C412834 ScrT protein 2000 09 07 2000 2001 2002 an antiterminator isolated from Clostridium acetobutylicum; amino acid sequence in first source; GenBank AF205034 1 *D001426 Bacterial Proteins Genetics 2000 Jun;155(2):71-80 THA THA M0369072 ScrT protein C0960508 0 T116 Amino Acid, Peptide, or Protein T423391 ScrT protein 2000 09 07 T423392 scrT gene product 2000 09 07 C085268 Re 80 1994 02 11 2001 01 19 1995 1996 1997 1998 1999 2000 2001 2001A 2001B 2002 structure given in first source; an anti-angiogenic agent 6 *D001565 Benzoates *D013764 Tetrahydronaphthalenes D012176 Retinoids Eur J Pharmacol 1993 Nov 2;249(1):113-6 THA CCR CCR M0226365 Re 80 C0250727 116193-60-3 T109 Organic Chemical T121 Pharmacologic Substance M0226365 M0226363 T256370 Re 80 T256369 Re-80 M0226363 4-(1-hydroxy-3-oxo-3-(5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid C0250726 T109 Organic Chemical T121 Pharmacologic Substance M0226365 M0226363 T256368 4-(1-hydroxy-3-oxo-3-(5,6,7,8-tetrahydro-3-hydroxy-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid C051756 tipredane 1987 04 28 2001 01 19 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source; RN given refers to (11beta,17alpha)-isomer 16 *D000730 Androstadienes Arzneimittelforschung 1986;36(12):1787 MGR WXM WXM M0147151 tipredane C0076716 85197-77-9 M0147151 M0147149 T177156 tipredane USAN 1987, p. 331 T177153 17-(ethylthio)-9-fluoro-11-hydroxy-17-(methylthio)androsta-1,4-dien-3-one M0147149 SQ 27239 C0143378 M0147151 M0147149 T177154 SQ 27239 T177155 SQ-27239 C027664 hypobromous acid 1975 01 01 2000 09 08 2001 2002 19 BROMINE (75-82) *D001959 Bromates Biochemistry 1975;14(11):2389 Steroids 1980;36(4):2667 RLS BMB sjn M0089736 hypobromous acid C0063226 13517-11-8 T130 Indicator, Reagent, or Diagnostic Aid T197 Inorganic Chemical 13824-97-0 (K salt) 36505-09-6 (radical ion(1-)) M0089736 M0317399 M0089736 M0317398 M0089736 M0089734 T119739 hypobromous acid T119736 hydrogen oxybromide T423394 HObr 2000 09 07 M0317399 hypobromous acid, ion (1-) C0899066 36505-09-6 T130 Indicator, Reagent, or Diagnostic Aid T197 Inorganic Chemical M0089736 M0317399 T347399 hypobromous acid, ion (1-) 1999 08 18 M0317398 hypobromous acid, potassium salt C0899065 13824-97-0 T130 Indicator, Reagent, or Diagnostic Aid T197 Inorganic Chemical M0089736 M0317398 T347398 hypobromous acid, potassium salt 1999 08 18 M0089734 hypobromous acid, sodium salt C0142863 0 T130 Indicator, Reagent, or Diagnostic Aid T197 Inorganic Chemical M0089736 M0089734 T119737 hypobromous acid, sodium salt T119738 sodium hypobromite C098216 glypican 3 1996 03 21 2001 08 15 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 a putative extracellular proteoglycan; mutations in GPC3 cause the Simpson-Golabi-Behmel syndrome (SGBS); amino acid sequence in first source; GenBank L47125 47 *Heparitin Sulfate (1996-1999) *Proteoglycans (1996-1999) *D019812 Heparan Sulfate Proteoglycan Nat Genet 1996 Mar;12(3):241-7 PML TWD TWD M0258023 glypican 3 C0386983 0 T288028 glypican 3 T288027 glypican-3 T288025 GPC3 gene product T288026 GPC3 protein C118339 SycD protein 1999 04 16 2001 08 15 1999 2000 2001 2001A 2002 a chaperone for YopB and YopD; isolated from Yersinia pestis; amino acid sequence in first source 4 *D018832 Molecular Chaperones D001426 Bacterial Proteins Infect Immun 1989 May;57(5):1491-8 THA CCR CCR M0303342 SycD protein C0765639 0 T333347 SycD protein T333346 sycD gene product T333345 lcrH gene product C072547 epristeride 1992 02 28 2001 01 19 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 18 *D000730 Androstadienes D013741 Testosterone 5-alpha-Reductase Q000037 antagonists ; inhibitors Endocrinology 1992 Feb;130(2):685-94 RLS WXM WXM M0196485 epristeride C0209904 119169-78-7 M0196485 M0196481 M0196485 M0196483 T226490 epristeride USAN (1992) T226484 17-N-t-butylcarboxamide androst-3,5-diene-3-carboxylic acid M0196481 ONO-9302 C0649390 M0196485 M0196481 T226486 ONO-9302 T226485 ONO 9302 M0196483 SK;F-105657 C0142484 M0196485 M0196483 T226488 SK;F-105657 T226489 SKF 105657 T226487 SK;F 105657 C005939 muconic acid 1973 01 01 2000 07 31 2001 2002 a metabolite of benzene; reported to be a reliable indicator of occupational exposure to benzene; structure given in first source 103 *FATTY ACIDS, UNSATURATED (73-76) DICARBOXYLIC ACIDS (73-82) D013011 Sorbic Acid *Q000031 analogs ; derivatives Arch Microbiol 110(2-3):253;1976 Helv Chim Acta 58(2):453;1975 J Bacteriol 127(3):1098;1976 NLM TWD sjn M0047821 muconic acid C0066918 2,4-hexadienedioic acid 505-70-4 T109 Organic Chemical T123 Biologically Active Substance 3588-17-8 ((E,E)-isomer) M0047821 M0309367 M0047821 M0047819 M0047821 M0047820 T077824 muconic acid M0309367 muconic acid, (E,E)-isomer C0894949 3588-17-8 T109 Organic Chemical T123 Biologically Active Substance M0047821 M0309367 T339367 muconic acid, (E,E)-isomer 1999 08 18 M0047819 cis,cis-muconate C0602349 T109 Organic Chemical T123 Biologically Active Substance M0047821 M0047819 T077822 cis,cis-muconate M0047820 trans,trans-muconic acid C0602350 T109 Organic Chemical T123 Biologically Active Substance M0047821 M0047820 T077823 trans,trans-muconic acid C005910 acetylfuratrizine 1974 01 01 2001 01 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *TRIAZINES (74-78) *D009581 Nitrofurans Jap J Urol 64(4):281;1973 Jpn J Bacteriol 30(1):113;1975 NLM TWD TWD M0047774 acetylfuratrizine C0050516 N-(6-(2-(5-nitro-2-furyl)vinyl)- 1,2,4-triazin-3-yl)acetamide 1789-26-0 T077777 acetylfuratrizine Negwer 1333 T077776 panfuran acetate C024220 D 53 1980 05 13 2000 07 31 2001 2002 ribosomal vaccine from Klebsiella pneumoniae, Streptococcus pneumoniae, Streptococcus pyogenes A(12) ; Haemophilus influenzae 8 *D001428 Bacterial Vaccines *D018073 Haemophilus Vaccines *D022242 Pneumococcal Vaccines *D022541 Streptococcal Vaccines D006193 Haemophilus influenzae Q000276 immunology D007711 Klebsiella pneumoniae Q000276 immunology D012270 Ribosomes Q000276 immunology D013296 Streptococcus pneumoniae Q000276 immunology D013297 Streptococcus pyogenes Q000276 immunology Arzneim Forsch 1980;30(1a):187-220 MEG nns sjn M0082181 D 53 C0057021 D 53 67880-78-8 T121 Pharmacologic Substance T129 Immunologic Factor M0082181 M0082180 T112184 D 53 M0082180 MS D 53 C0129155 M0082181 M0082180 T112183 MS D 53 C005849 2,2,2-trichloroethanol 1969 01 01 2000 12 22 1995 1996 1997 1998 1999 2000 2001 2001A 2002 proposed as basal anesthetic, hypnotic; structure 85 *ALCOHOL, ETHYL (69-75) *CHLOROHYDRINS (75-80) CHLORINE (72-76) D005023 Ethylene Chlorohydrin *Q000031 analogs ; derivatives Analyst 102(1218):672;1977 Anesthesiology 48(2):104;1978 Eur J Biochem 84:79;1978 J Chromatogr 107(1):107;1975 J Chromatogr 150(1):212;1978 J Chromatogr 153(2):473;1978 J Occup Med 18(4):224;1976 Jpn J Ind Health 18:11;1976 Jpn J Ind Health 19:251;1977 Scand J Work Environ Health 1(4):243;1975 Scand J Work Environ Health 2(4):212;1976 NLM CCR CCR M0047662 2,2,2-trichloroethanol C0045268 115-20-8 T109 Organic Chemical T121 Pharmacologic Substance T077665 2,2,2-trichloroethanol Merck Index, 9th ed, p. 1237, #9318 T077664 trichloroethanol C007111 conessine 1970 01 01 2001 01 30 1998 1999 2000 2001 2001A 2002 RN given refers to (3 beta)-isomer 1 *PREGNENES (70-81) PYRROLIDINES (70-75) *D000470 Alkaloids NLM TWD TWD M0050088 conessine C0056237 3 beta-(dimethylamino)con-5-enine 546-06-5 5913-82-6 (di-HBr(3beta)-isomer) M0050088 M0309837 T080091 conessine Merck Index, 9th ed, p.321, #2465 M0309837 conessine dihydrobromide, (3beta)-isomer C0951606 5913-82-6 M0050088 M0309837 T339837 conessine dihydrobromide, (3beta)-isomer 1999 08 18 C417003 C5L2 protein 2000 12 19 2001 08 13 2001 2001A 2002 A putative chemoattractant receptor, is expressed in granulocyte and immature dendritic cells, but not in mature dendritic cells; amino acid sequence in first source 2 *D019707 Receptors, Chemokine Mol Immunol. 2000 Jun;37(8):407-12 SZM TWD TWD M0374855 C5L2 protein C0962576 0 T116 Amino Acid, Peptide, or Protein T192 Receptor T431329 C5L2 protein 2000 12 19 T431330 C5L2 gene product 2000 12 19 C007117 copper 2,2'-bicinchoninate 1974 01 01 2001 01 30 1998 1999 2000 2001 2001A 2002 reagent for determining uric acid in blood 1 COPPER (74-82) *D011804 Quinolines Clin Chem 19(10):1184;1973 NLM TWD TWD M0050097 copper 2,2'-bicinchoninate C0056287 Copper, ((2,2'-biquinoline)-4,4'-dicarboxylato(2-)-N(1),N(1)')- 76109-99-4 T080100 copper 2,2'-bicinchoninate T080099 Cu(II)-2,2'-bicinchoninate C005891 voacamine 1972 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 3 *ALKALOIDS (72-79) *INDOLES (72-79) AZEPINES (74-79) D007050 Ibogaine *Q000031 analogs ; derivatives NLM RLS NLM M0047745 voacamine C0282813 12-methoxy-13-((3 alpha)-17-methoxy-17-oxovobasan- 3-yl)ibogamine-18-carboxylic acid methyl ester 3371-85-5 T077748 voacamine Merck Index, 9th ed, p. 1293, #9696 C105049 nibentan 1997 04 09 2001 01 03 1998 1999 2000 2001 2001A 2002 MF: C22-H29-N3-O3 HCl; MF does not agree with chemical name in text 5 *D001549 Benzamides J Pharmacol Exp Ther 1997 Nar;280(3):1137-46 PML TWD TWD M0274186 nibentan C0537145 0 T109 Organic Chemical T121 Pharmacologic Substance M0274186 M0274184 T304191 nibentan M0274184 HE 11 C0537144 T109 Organic Chemical T121 Pharmacologic Substance M0274186 M0274184 T304189 HE 11 T304190 HE-11 C005895 zinc dibenzyldithiocarbamate 1972 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *THIOCARBAMATES (72-79) BENZYL CPDS (72-76) ZINC (72-79) D015039 Ziram *Q000031 analogs ; derivatives NLM RLS NLM M0047751 zinc dibenzyldithiocarbamate C0602331 (T-4)-bis(bis(phenylmethyl)carbamodithioato-S,S')zinc 14726-36-4 T077754 zinc dibenzyldithiocarbamate C050456 nickel-palladium alloy 1987 01 15 2001 01 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 used for magnetic induction of hyperthermia as a brain implant for therapy of brain neoplasms 1 *D009532 Nickel *D010165 Palladium D000497 Alloys J Neurooncol 1986;4(2):175 MGR CCR CCR M0144058 nickel-palladium alloy C0628943 106747-79-9 T130 Indicator, Reagent, or Diagnostic Aid T197 Inorganic Chemical T174063 nickel-palladium alloy T174062 Ni-Pd alloy C005906 alpha-isopropylmalate 1973 01 01 1982 06 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 12 PROPANE (73-76) PROPANE/analogs (73-82) *D008293 Malates Biochemistry 12(17):3346;1973 NLM CHA NLM M0047768 alpha-isopropylmalate C0051386 2-hydroxy-2-(1-methylethyl)butanedioic acid 3237-44-3 T077771 alpha-isopropylmalate C007125 cordycepin-C 1974 01 01 2001 01 30 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 the C-C nucleoside analog of cordycepin; structure 0 *D003839 Deoxyadenosines Carb. Res. 29(2):525;1973 NLM TWD TWD M0050112 cordycepin-C C0056332 8-(3'-deoxy-beta-D-erythro-ribofuranosyl)adenine 51771-54-1 T080115 cordycepin-C T080114 cordycepin C C005909 tetrahydrotriamcinolone 1973 01 01 1983 07 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN given is for cpd named as tetrahydro deriv of a pregnadiene 0 *TRIAMCINOLONE (73-75) D014221 Triamcinolone *Q000031 analogs ; derivatives Med Clin North Am 57(5):1167;1973 NLM ACS NLM M0047772 tetrahydrotriamcinolone C0076285 51855-44-8 T077775 tetrahydrotriamcinolone C007131 corrinoid 1975 01 01 2001 01 30 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a tetrapyrrole 97 *VITAMIN B 12 (75-93) *D011166 Porphyrins Biochem Biophys Res Comm 72(3):1077;1976 Biochemistry 14(16):3707;1975 Helv Chim Acta 59(3):924;1976 J Bacteriol 134(2):668;1978 Mikrobiologiia 47(3):451;1978 Z Naturforsch Section C 30(4):460;1975 NLM TWD TWD M0050121 corrinoid C0056356 262-76-0 T080124 corrinoid T080123 corrin C007141 coumazoline 1975 01 01 2001 01 30 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 BENZOFURANS (75-82) *D007093 Imidazoles Acta Otorhinolaryngol Belg 28(3):355;1974 NLM TWD TWD M0050147 coumazoline C0602991 2-(2-ethyl-3-benzofurylmethyl)imidazol-2-ine 37681-00-8 M0050147 M0050146 T080150 coumazoline M0050146 L 5818 C0602990 M0050147 M0050146 T080149 L 5818 C005914 DONS 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 new impurity in Schaeffer's salt; structure 0 ETHERS (74-75) *D009282 Naphthalenesulfonates J Assoc Anal Chem 54(1):137;1971 NLM NLM M0047785 DONS C0878545 6,6'-oxybis(2-naphthalenesulfonic acid) 31034-03-4 T077788 DONS C005919 9-oxo-9H-pyrrolo(1,2-a)indole 1974 01 01 1983 08 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 PYRROLES (74-82) *D007211 Indoles Farmaco 27(1):60;1972 NLM JSL NLM M0047791 9-oxo-9H-pyrrolo(1,2-a)indole C0602340 0 T077794 9-oxo-9H-pyrrolo(1,2-a)indole C005920 1-hydroxyimidazole-3-oxide 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CYCLIC N-OXIDES (74-76) *D007093 Imidazoles Farmaco 27(1):46;1972 NLM NLM M0047792 1-hydroxyimidazole-3-oxide C0602341 1H-Imidazole, 1-hydroxy-, 3-oxide 35321-46-1 T077795 1-hydroxyimidazole-3-oxide C005922 daphnetin-8-glucoside 1974 01 01 1998 04 06 1998 1999 2000 2001 2002 RN given refers to (beta)-isomer 0 *COUMARINS (74-79) *GLYCOSIDES (74-82) *D014468 Umbelliferones J Pharm Sci 62(8):1360;1973 NLM BQV NLM M0047794 daphnetin-8-glucoside C0602342 2H-1-Benzopyran-2-one, 8-(beta-D-glucopyranosyloxy)-7-hydroxy- 20853-56-9 T077797 daphnetin-8-glucoside C005924 cortivazol 1974 01 01 1982 07 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 24 *GLUCOCORTICOIDS (74-75) HYDROXYSTEROIDS (74-76) PYRAZOLES (74-82) *D011281 Pregnatrienes D005939 Glucocorticoids, Synthetic Boll Chim Farm 114(5):279;1975 Rev Clin Esp 129(5):491;1973 NLM CHA NLM M0047799 cortivazol C0056396 11 beta,17 alpha,21- trihydroxy-6,16 alpha-dimethyl-2'-phenylpregna- 2,4,6-trieno(3,2-c)pyrazol-20-one 21-acetate 1110-40-3 M0047799 M0047796 M0047799 M0047798 M0047799 M0047797 T077802 cortivazol Negwer, 5th ed, #5874 M0047796 H-3625 C0120583 M0047799 M0047796 T077799 H-3625 M0047798 idaltim C0123158 M0047799 M0047798 T077801 idaltim M0047797 dilaster C0114023 M0047799 M0047797 T077800 dilaster C060634 4-(9-acridinylamino)-N-(glycyl-histidyl-lysyl-glycyl)aniline 1989 09 11 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 *D000609 Aminoacridines *D009842 Oligopeptides Anticancer Drug Des 1989;4(1):37 RLS CCR CCR M0168389 4-(9-acridinylamino)-N-(glycyl-histidyl-lysyl-glycyl)aniline C0638097 121034-91-1 T198394 4-(9-acridinylamino)-N-(glycyl-histidyl-lysyl-glycyl)aniline T198393 4-AcA-Gly-His-Lys-Gly-A T198392 4-AGHLGA C005929 14-dehydro-19-nortestosterone 1973 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *NANDROLONE (73-75) D009277 Nandrolone *Q000031 analogs ; derivatives Steroids 22(1):99;1973 NLM NLM M0047807 14-dehydro-19-nortestosterone C0602345 35644-61-2 T077810 14-dehydro-19-nortestosterone C005931 7 alpha-methyl-14-dehydro-19-nortestosterone 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ANDROSTENOLS (74-75) KETOSTEROIDS (74-75) D009277 Nandrolone *Q000031 analogs ; derivatives Steroids 22(1):99;1973 NLM NLM M0047808 7 alpha-methyl-14-dehydro-19-nortestosterone C0602346 0 T077811 7 alpha-methyl-14-dehydro-19-nortestosterone C005932 17-hydroxyprogesterone 17-(9-oxo-10-chlorodecanoate) 1973 01 01 1982 11 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 DECANOIC ACIDS (75-76) FATTY ACIDS (73-75) KETO ACIDS (73-76) *D006908 Hydroxyprogesterones Steroids 22(1):139;1973 NLM VSR NLM M0047809 17-hydroxyprogesterone 17-(9-oxo-10-chlorodecanoate) C0602347 Pregn-4-ene-3,20-dione, 17-((10-chloro-1,9-dioxodecyl)oxy)- 40946-49-4 T077812 17-hydroxyprogesterone 17-(9-oxo-10-chlorodecanoate) C005935 Vesitan 1973 01 01 1985 07 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 contains thiopropazate ; chlorphencyclan 0 *ETHYLAMINES (73-79) *THIOPROPAZATE (73-85) *D003510 Cyclohexanes *D010640 Phenothiazines D004338 Drug Combinations Dtsch Med Wochenschr 98(21):1071;1973 NLM LCR NLM M0047813 Vesitan C0602348 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)-, acetate (ester), mixt. with 2-((1-(4-chlorophenyl)cyclohexyl)oxy)-N,N-diethylethanamine 8063-62-5 T077816 Vesitan Merck Index, 9th ed, p. 279, in #2166 C005936 paromamine 1973 01 01 1998 04 22 1998 1999 2000 2001 2002 RN given refers to (D)-isomer 1 *AMINO SUGARS (73-74) *GLYCOSIDES (73-74) *D000617 Aminoglycosides J Antibiot (Tokyo) 25(9):530;1972 J Antibiot (Tokyo) 28(8):574;1975 NLM BQV NLM M0047814 paromamine C0070118 534-47-4 T077817 paromamine C071586 araloside D 1991 12 13 1995 06 23 1995 1996 1997 1998 1999 2000 2001 2002 structure given in first source; isolated from the root bark of Aralia chinesis L. 1 *D012503 Saponins D004365 Drugs, Chinese Herbal Yao Hsueh Hsueh Pao 1991;26(3):197 IDX MLH TPW M0194371 araloside D C0648506 Olean-12-en-28-oic-acid, 3-((O-beta-D-glucopyranosyl-(1-2)-O-beta-D-xylopyranosyl-(1-2)-alpha-L-arabinopyranosyl)oxy)-, (3beta)- 135560-19-9 T224376 araloside D C056755 nickel(III)oxide 1988 09 08 2001 01 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 2 *D009532 Nickel Ind Health 1988;26(2):115 TPW CCR CCR M0159124 nickel(III)oxide C0068692 1314-06-3 T197 Inorganic Chemical T189129 nickel(III)oxide T189128 nickel sesquioxide C005940 isophorone 1969 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 10 *CYCLOHEXANE (69-75) *D003512 Cyclohexanones Toxicol Eur Res 1(4):209;1978 NLM NLM M0047822 isophorone C0064035 3,5,5-trimethyl-2-cyclohexen-1-one 78-59-1 T077825 isophorone C077991 araloside G 1992 12 10 2001 06 11 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from Arala elata; structure given in first source 1 *D012503 Saponins D004365 Drugs, Chinese Herbal Yao Hsueh Hsueh Pao 1992;27(7):528-32 RLS TWD TWD M0209202 araloside G C0655370 Olean-12-en-28-oic--acid, 3-((O-beta-D-glucopyranosyl-(1-3)-O-(beta-D-glucopyranosyl-(1-4))-beta-D-glucopyranosyl)oxy)-, beta-D-glucopyranosyl ester, (3beta)- 144077-05-4 T239207 araloside G T239206 3-O-beta-D-glucopyranosyl(1-3)(beta-D-glucopyranosyl(1-4))-beta-D-glucopyranosyl-oleanolic acid-28-O-beta-D-glucopyranoside C120242 aquilegioside A 1999 09 30 1999 2000 2001 2002 cycloartane-type glycoside from Aquilegia flabellata; structure in first source 1 *D012503 Saponins Phytochemistry 1999 Jun;51(3):449-52 TWD TWD M0333064 aquilegioside A C0769802 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T364686 aquilegioside A T364687 22-3beta,16alpha,29-trihydroxy-cycloart-24-en-26,22-olide 3-O-beta-D-glucopyranosyl-(1-6)-beta-D-glucopyranosyl-(1-2)-alpha-L-arabinopyranoside C005951 dimetilan 1969 01 01 1982 07 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *INSECTICIDES (69-75) *PYRAZOLES (69-76) *D002219 Carbamates NLM CHA NLM M0047835 dimetilan C0058280 1-dimethylcarbamoyl-2-methyl-4-pyrazolyl dimethylcarbamate 644-64-4 T077838 dimetilan C006038 AB 64 1974 01 01 2001 01 30 1997 1998 1999 2000 2001 2001A 2002 new phenolic, indicator-pigment antibiotic isolated from Actinomadura roseoviolacea var. rubescens 0 D010636 Phenols D010860 Pigments J Antibiot (Tokyo) 26(9):492;1973 NLM TWD TWD M0048047 AB 64 C0602405 Antibiotic AB 64 50863-62-2 T078050 AB 64 T078049 AB-64 C120243 aquilegioside B 1999 10 05 1999 2000 2001 2002 cycloartane-type glycoside from Aquilegia flabellata; structure in first source 1 *D012503 Saponins Phytochemistry 1999 Jun;51(3):449-52 TWD TWD M0333447 aquilegioside B C0769804 0 T109 Organic Chemical T123 Biologically Active Substance T365281 aquilegioside B T365282 22-3beta,16alpha,29-trihydroxycycloart-24-en-26,22-olide 3-O-beta-D-glucopyranosyl-(1-2)-alpha-L-arabinopyranoside C005968 carboxymuconolactone 1974 01 01 1983 08 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 LACTONES (74-81) *D014233 Tricarboxylic Acids Biochemistry 12(18):3537;1973 NLM ACS NLM M0047880 carboxymuconolactone C0376775 2-Furanacetic acid, 2-carboxy-2,5-dihydro-5-oxo- 13249-46-2 T077883 carboxymuconolactone C005971 5-ethyluracil-1-beta-D-xylopyranoside 1974 01 01 1982 10 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *NUCLEOSIDES (74-75) *URACIL (74-75) URACIL/*analogs (75-82) *D011741 Pyrimidine Nucleosides Chem Pharm Bull 21(6):1382;1973 NLM VSR NLM M0047890 5-ethyluracil-1-beta-D-xylopyranoside C0602352 0 T077893 5-ethyluracil-1-beta-D-xylopyranoside C005972 5-ethyluracil-1-beta-D-galactopyranoside 1974 01 01 1982 10 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *NUCLEOSIDES (74-75) *URACIL (74-75) URACIL/*analogs (75-82) *D011741 Pyrimidine Nucleosides Chem Pharm Bull 21(6):1382;1973 NLM VSR NLM M0047891 5-ethyluracil-1-beta-D-galactopyranoside C0602353 0 T077894 5-ethyluracil-1-beta-D-galactopyranoside C058877 2-(4-isobutylcyclohexyl)-2-oxoethyl benzenesulfonate 1989 04 26 2001 02 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source; RN from Toxlit 2 *D001557 Benzenesulfonates J Chromatogr 1988;433:282 MGR TWD TWD M0164015 2-(4-isobutylcyclohexyl)-2-oxoethyl benzenesulfonate C0636430 84856-18-8 T109 Organic Chemical T121 Pharmacologic Substance M0164015 M0164017 T194020 2-(4-isobutylcyclohexyl)-2-oxoethyl benzenesulfonate M0164017 FL 386 C0636431 T109 Organic Chemical T121 Pharmacologic Substance M0164015 M0164017 T194022 FL 386 T194021 FL-386 C080547 SC65 protein 1993 05 03 2001 02 02 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; a 65-kDa protein located in the pairing zone of the rat synaptonemal complex 1 *D004268 DNA-Binding Proteins D013573 Synaptonemal Complex Biochem Cell Biol 1992 Oct-Nov;70(10-11):1030-8 THA WXM WXM M0215192 SC65 protein C0658257 0 T245197 SC65 protein T245196 synaptonemal complex 65-kDa protein C007986 4'-hydroxyasperentin 1974 01 01 2001 02 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 minor metabolite of Aspergillus flavus; structure 0 *PYRANS (74-82) *D003374 Coumarins D009183 Mycotoxins J Chem Soc (Perkin I):22:2704;1973 NLM TWD TWD M0051493 4'-hydroxyasperentin C0603358 1H-2-Benzopyran-1-one, 3,4-dihydro-6,8-dihydroxy-3-((tetrahydro-4-hydroxy-6-methyl-2H-pyran-2-yl)methyl)- 51484-09-4 T081496 4'-hydroxyasperentin T081495 3,4-dihydro-6,8-dihydroxy-3-(4-hydroxy-6-methyltetrahydropyran-2-ylmethyl)isocoumarin C005985 3,6-dioxohexahydropyrrolo(1,2-a)pyrazine 1974 01 01 1982 09 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 isolated from starfish Luidia clathrata; structure 0 PYRROLIDINES (74-82) *D010879 Piperazines Experientia 29(5):521;1973 NLM VSR NLM M0047917 3,6-dioxohexahydropyrrolo(1,2-a)pyrazine C0602356 0 T077920 3,6-dioxohexahydropyrrolo(1,2-a)pyrazine C006104 U 0521 1969 01 01 2001 08 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 catechol methyltransferase antagonist; structure 46 *D011427 Propiophenones Am J Physiol 228(6):1702;1975 Biochem Pharmacol 28(7):1221;1979 Cardiovasc Res 1979;13(12):723 Circ Res 1980;46(1):22 Clin Exp Pharmacol Physiol Suppl 2:39;1975 J Pharm Pharmacol 29(8):502;1977 Naunyn Schmiedebergs Arch Pharmacol 1979;307(3):235 Naunyn Schmiedebergs Arch Pharmacol 286:401;1975 Naunyn Schmiedebergs Arch Pharmacol 292(3):205;1976 Naunyn Schmiedebergs Arch Pharmacol 292(3):219,231;1976 Naunyn Schmiedebergs Arch Pharmacol 293(2):115;1976 Naunyn Schmiedebergs Arch Pharmacol 295(2):141;1976 Naunyn Schmiedebergs Arch Pharmacol 296(3):217,279;1977 Naunyn Schmiedebergs Arch Pharmacol 304(2):147;1978 Pharmacology 18(5):228;1979 Proc Soc Exp Biol Med 156:315;1977 NLM TWD TWD M0048217 U 0521 C0077603 1-(3,4-dihydroxyphenyl)-2-methyl-1-propanone 5466-89-7 M0048217 M0048214 T078220 U 0521 T078218 U-0521 T078219 U0521 M0048214 3',4'-dihydroxy-2-methylpropiophenone C0094192 M0048217 M0048214 T078217 3',4'-dihydroxy-2-methylpropiophenone C084422 NS3 protein, hepatitis C virus 1993 12 23 2002 05 24 1999 2000 2001 2001A 2002 2002A from hepatitis C virus isolated in Hunan; has serine proteinase, RNA helicase and ATPase activity;; amino acid sequence given in first source 268 *D017361 Viral Nonstructural Proteins D000251 Adenosinetriphosphatase D012697 Serine Endopeptidases D016174 Hepacivirus D020365 RNA Helicases Chin Med J (Engl) 1993 Jul;106(7):522-6 BMB BMB BMB M0224280 NS3 protein, hepatitis C virus C0249187 0 M0224280 M0224278 T254285 NS3 protein, hepatitis C virus T254280 HCV-Hun NS3 protein T254281 HCV-Hunan NS3 protein T254282 NS3 protein, HCV T254284 p70(NS3) T495184 NS3 protease, hepatitis C virus 2002 05 24 M0224278 hepatitis C virus RNA helicase C0527944 M0224280 M0224278 T254283 hepatitis C virus RNA helicase C005990 N-(2,4-dinitrophenyl)hexamethylenediamine 1974 01 01 1982 09 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *NITROBENZENES (74-77) DIAMINES (74-77) DINITROBENZENES (77-82) *D003959 Diamines Eur J Biochem 35(3):540;1973 NLM VSR NLM M0047928 N-(2,4-dinitrophenyl)hexamethylenediamine C0602365 1,6-Hexanediamine, N-(2,4-dinitrophenyl)- 40299-04-5 T077931 N-(2,4-dinitrophenyl)hexamethylenediamine C419193 ARIH1 protein 2001 01 31 2001 2002 binds E2 enzymes of the ubiquitin degradation system; ortholog of ariadne from Drosophila; amino acid sequence in first source 1 *D002352 Carrier Proteins Cytogenet Cell Genet 2000;90(3-4):242-5 THA THA M0377561 ARIH1 protein C0963644 0 T116 Amino Acid, Peptide, or Protein T434675 ARIH1 protein 2001 01 31 T434676 ARIH1 gene product 2001 01 31 C080574 SmIrV1 protein 1993 05 03 2001 02 02 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source 1 *D015801 Helminth Proteins D000947 Antigens, Helminth D012550 Schistosoma mansoni J Biol Chem 1993 Apr 15;268(11):7692-8 THA WXM WXM M0215250 SmIrV1 protein C0658277 0 T245255 SmIrV1 protein T245254 SmIrV1 gene product C080581 CAM1 protein 1993 05 03 2001 02 02 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 415 amino acid residues, MW 47,092 Da; amino acid sequence given in first source 2 *D005656 Fungal Proteins D012441 Saccharomyces cerevisiae Yeast 1993 Feb;9(2):151-63 BXB WXM WXM M0215265 CAM1 protein C0658287 0 T245270 CAM1 protein T245269 CAM1 gene product C068569 E coli O18 O-specific polysaccharide-cholera toxin 1991 05 26 2000 07 31 2001 2002 O-specific polysaccharide isolated from serotype 18 Escherichia coli lipopolysaccharide covalently coupled to cholera toxin 1 *BACTERIAL VACCINES (1991-2000) *CHOLERA TOXIN (1991-2000) *D000942 Antigens, Bacterial *D002772 Cholera Toxin *D022121 Cholera Vaccines D004926 Escherichia coli J Infect Dis 1991;163(5):1040 TPW nns sjn M0187477 E coli O18 O-specific polysaccharide-cholera toxin C0645513 0 T121 Pharmacologic Substance T129 Immunologic Factor T217482 E coli O18 O-specific polysaccharide-cholera toxin T217481 O-PS-cholera toxin C087036 NS-5 protein, hepatitis C virus 1994 05 30 2001 08 03 1998 1999 2000 2001 2001A 2002 has been sequenced; can be cleaved to give p56/58(NS5A) and p66(NS5B) 247 *D017361 Viral Nonstructural Proteins D012324 RNA Replicase J Gen Virol 1994 May;75( Pt 5):1053-61 THA CCR CCR M0230610 NS-5 protein, hepatitis C virus C0254326 0 M0230610 M0230608 M0230610 M0230609 T260615 NS-5 protein, hepatitis C virus T260610 HCV NS-5 protein T260611 HCV NS5 protein T260612 NS5 protein, HCV M0230608 NS5A protein, HCV C0662849 M0230610 M0230608 T260613 NS5A protein, HCV M0230609 NS5B protein, HCV C0380178 M0230610 M0230609 T260614 NS5B protein, HCV C006141 MK 940 1974 01 01 2000 07 31 2001 2002 RN given refers to (trans)-isomer; structure 0 ANTIDEPRESSIVE AGENTS (74-75) *D003986 Dibenzocycloheptenes Am J Ophthalmol 76(5):641;1973 NLM TWD sjn M0048315 MK 940 C0602501 (5 alpha,10 alpha,11 beta)-10,11-dihydro-5-(3-(methylamino)propyl)-5,10-epoxy-5H-dibenzo(a,d)cyclohepten-11-0l, (Z)-2-butenedioate (1:1) salt 5154-92-7 T109 Organic Chemical T121 Pharmacologic Substance 23239-40-9 (maleate[1:1](5alpha,10alpha,11beta)-isomer) 5154-91-6 ((cis)-isomer) M0048315 M0309453 M0048315 M0309452 M0048315 M0048314 T078318 MK 940 Psychotropic Drugs Relat Cpds, 2d ed, p. 82, #219 UD 22:146o T078316 MK-940 M0309453 MK 940, (cis)-isomer C0895003 5154-91-6 T109 Organic Chemical T121 Pharmacologic Substance M0048315 M0309453 T339453 MK 940, (cis)-isomer 1999 08 18 M0309452 MK 940, maleate (1:1), (5alpha,10alpha,11beta)-isomer C0895002 23239-40-9 T109 Organic Chemical T121 Pharmacologic Substance M0048315 M0309452 T339452 MK 940, maleate (1:1), (5alpha,10alpha,11beta)-isomer 1999 08 18 M0048314 trans-10,11-dihydro-5,10-epoxy-5-(3-(methylamino)propyl)-5H-dibenzo(a,d)cyclohepten-11-ol hydrogen maleate C0602500 T109 Organic Chemical T121 Pharmacologic Substance M0048315 M0048314 T078317 trans-10,11-dihydro-5,10-epoxy-5-(3-(methylamino)propyl)-5H-dibenzo(a,d)cyclohepten-11-ol hydrogen maleate C006062 XK-19-2 1973 01 01 2001 05 30 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 basic peptide antibiotic produced by Streptomyces sp. MK-19 0 *PEPTIDES (73-84) PEPTIDES (84-93) *D017561 Antibiotics, Peptide J Antibiot (Tokyo) 26(8):471;1973 NLM CCR CCR M0048102 XK-19-2 C0602419 Antibiotic XK 19-2 37316-79-3 T078105 XK-19-2 T078104 antibiotic XK 19-2 T078103 XK 19-2 C087632 glycoprotein 6b, coronavirus 1994 07 08 2001 08 03 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a secreted nonstructural glycoprotein; amino acid sequence has been determined 2 *D017361 Viral Nonstructural Proteins Adv Exp Med Biol 1993;342:11-6 BMB CCR CCR M0232055 glycoprotein 6b, coronavirus C0255554 0 M0232055 M0232050 M0232055 M0232051 M0232055 M0232052 M0232055 M0232053 T262060 glycoprotein 6b, coronavirus T262059 6b protein, coronavirus T262054 6b gene product, coronavirus M0232050 6b gp, canine coronavirus (CCV) C0255549 M0232055 M0232050 T262055 6b gp, canine coronavirus (CCV) M0232051 6b gp, feline enteric coronavirus (FECV) C0255550 M0232055 M0232051 T262056 6b gp, feline enteric coronavirus (FECV) M0232052 6b gp, feline infectious peritonitis virus (FIPV) C0255551 M0232055 M0232052 T262057 6b gp, feline infectious peritonitis virus (FIPV) M0232053 6b gp, transmissible gastroenteritis virus (TGEV) C0255552 M0232055 M0232053 T262058 6b gp, transmissible gastroenteritis virus (TGEV) C067410 endothelium-dependent hyperpolarization factor 1991 03 21 2001 05 31 1999 2000 2000A 2001 2001A 2002 may be related to anandamide; released from endothelium of rat pulmonary arteries; nonprostanoid, nonidentified factor that contributes to endothelium-dependent relaxation by causing hyperpolarization of the vascular smooth muscle 332 *D001685 Biological Factors D004730 Endothelium, Vascular D011188 Potassium Am J Physiol 1991;260(2 Pt 1):L97 RLS TWD TWD M0184777 endothelium-dependent hyperpolarization factor C0082428 0 T123 Biologically Active Substance T214782 endothelium-dependent hyperpolarization factor T214781 EDHF C006131 CI 744 1974 01 01 2000 12 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 anesthetic composed of tiletamine ; zolazepam (flupyrazapone); diazepinone tranquilizer 46 *AZEPINES (74-77) *D013992 Tiletamine *D015041 Zolazepam D004338 Drug Combinations Am J Vet Res 36(5):695;1975 Invest Ophthalmol Vis Sci 18(8):8780;1979 J Am Vet Med Assoc 173(9):1127;1978 J Med Primatol 7(4):193;1978 Lab Animal Sci 22(6):878;1972 Vet Med Small Anim Clin 69(4):479;1974 Vet Med Small Anim Clin 71(6):764;1976 Vet Med Small Anim Clin 72(11):1722;1977 NLM CCR CCR M0048290 CI 744 C0055684 4-(2-fluorophenyl)-6,8-dihydro-1,3,8-trimethylpyrazolo(3,4-e)(1,4)diazepin-7(1H)-one, mixt. with 2-(ethylamino)-2-(2-thienyl)cyclohexanone hydrochloride 37291-85-3 T109 Organic Chemical T121 Pharmacologic Substance D000777 Anesthetics D000778 Anesthetics, Dissociative M0048290 M0048288 M0048290 M0048289 M0048290 M0048287 T078293 CI 744 T078288 CI-744 T078289 CI744 M0048288 Telazol C0145108 T109 Organic Chemical T121 Pharmacologic Substance M0048290 M0048288 T078291 Telazol M0048289 Tilazol C0145939 T109 Organic Chemical T121 Pharmacologic Substance M0048290 M0048289 T078292 Tilazol M0048287 Zoletil C0149474 T109 Organic Chemical T121 Pharmacologic Substance M0048290 M0048287 T078290 Zoletil C037061 UDPglucose-glycoprotein glucose-1-phosphotransferase 1983 02 15 2001 05 31 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from embryonic chicken neural retina; glucose is linked by phosphodiester bonds to mannose of a cell surface glycoprotein; catalyzes the transfer of alpha Glc-1-P from UDP-Glc to mannose residues on acceptor glycoproteins 9 *PHOSPHOTRANSFERASES (83-93) *D017855 Transferases (Other Substituted Phosphate Groups) Cell 1982;31(2):739 MEG CCR CCR M0112404 UDPglucose-glycoprotein glucose-1-phosphotransferase C0077752 EC 2.7.8.19 T142408 UDPglucose-glycoprotein glucose-1-phosphotransferase T142406 Glc-phosphotransferase T142407 GlcPTase C070341 oxygen-evolving complex, 23 kDa precursor 1991 09 13 2001 08 03 1997 1998 1999 2000 2001 2001A 2002 from wheat; MW 23 kDa; photosynthetic complex; amino acid sequence given in first source 3 *D011498 Protein Precursors *D016197 Photosynthetic Reaction Center, Plant D014908 Triticum Plant Mol Biol 1991;17(1):179 RLS TWD TWD M0191597 oxygen-evolving complex, 23 kDa precursor C0134408 Protein (wheat clone p23K-1 23-kilodalton photosystem II-associated precursor reduced) 140208-15-7 T221602 oxygen-evolving complex, 23 kDa precursor T221599 23-kDa photosystem II protein precursor T221600 OVP 23, precursor T221601 photosystem II 23K protein precursor C037363 UDPgalactose - UDP-N-acetylglucosamine galactosephosphotransferase 1983 03 29 2001 05 31 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 forms UDP N-acetylglucosamine-6-phosphogalactose 6 *PHOSPHOTRANSFERASES (83-93) *D017855 Transferases (Other Substituted Phosphate Groups) FEBS Lett 1983;151(1):15 MEG CCR CCR M0113131 UDPgalactose - UDP-N-acetylglucosamine galactosephosphotransferase C0207864 EC 2.7.8.18 T143135 UDPgalactose - UDP-N-acetylglucosamine galactosephosphotransferase T143134 galactose-1-phosphotransferase T143133 UDPgalactose-N-acetylglucosamine galactose-1-phosphotransferase C006089 ICR 340 1975 01 01 2001 01 30 1998 1999 2000 2001 2001A 2002 ICR acridine half-mustard cpd; RN ; NM refer to di-HCl 0 *ACRIDINES (75-80) *NAPHTHYRIDINES (75-82) *D009588 Nitrogen Mustard Compounds Proc Natl Acad Sci USA 71(11):4416;1974 NLM TWD TWD M0048191 ICR 340 C0602443 N-(2-chloroethyl)-N'-(7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)-N-ethyl-1,3-propanediamine, dihydrochloride 38915-28-5 T078194 ICR 340 T078193 ICR-340 C419204 YO 1 compound 2001 01 31 2001 2002 structure in first source 1 *D004151 Dipeptides Bioorg Med Chem Lett 2000 Oct 2;10(19):2217-21 THA THA M0377572 YO 1 compound C0963653 0 T109 Organic Chemical T121 Pharmacologic Substance T434697 YO 1 compound 2001 01 31 T434698 YO-1 compound 2001 01 31 C419203 Cyan 39 2001 01 31 2001 2002 structure in first source 1 *D013844 Thiazoles Bioorg Med Chem Lett 2000 Oct 2;10(19):2201-4 THA THA M0377571 Cyan 39 C0963652 0 T109 Organic Chemical T121 Pharmacologic Substance T434695 Cyan 39 2001 01 31 T434696 Cyan-39 2001 01 31 C419205 YO 2 compound 2001 01 31 2001 2002 structure in first source 2 *D004151 Dipeptides Bioorg Med Chem Lett 2000 Oct 2;10(19):2217-21 THA THA M0377573 YO 2 compound C0963654 0 T109 Organic Chemical T121 Pharmacologic Substance T434699 YO 2 compound 2001 01 31 T434700 YO-2 compound 2001 01 31 C419206 1-(3,5-dichloropyrid-4-ylmethyl)-5-cyclopentoxy-6-methoxyphthalazine 2001 01 31 2001 2002 a PDE4 inhibitor; structure in first source 1 *D010793 Phthalazines Bioorg Med Chem Lett 2000 Oct 2;10(19):2235-8 THA THA M0377574 1-(3,5-dichloropyrid-4-ylmethyl)-5-cyclopentoxy-6-methoxyphthalazine C0963655 0 T109 Organic Chemical T121 Pharmacologic Substance T434701 1-(3,5-dichloropyrid-4-ylmethyl)-5-cyclopentoxy-6-methoxyphthalazine 2001 01 31 T434702 1-diClPMe-cPMP 2001 01 31 C006164 S 2160 1975 01 01 2001 06 28 1999 2000 2001 2001A 2002 synthetic chromogenic substrate for thrombin; liberates p-nitroaniline 17 ANILIDES (75-81) *D009842 Oligopeptides Biokhimiia 42(8):1487;1977 FEBS Lett 1980;109(2):252 Jpn J Clin Pathol 25(2):167;1977 Res Commun Chem Pathol Pharmacol 18(3):543;1977 Thromb Res 10(4):549;1977 Thromb Res 5(2):185;1974 Thromb Res 5(5):621;1974 Thromb Res 7(4):533;1975 NLM CCR CCR M0048365 S 2160 C0073754 L-argininamide, N-benzoyl-L-phenylalanyl-L-valyl-N-(4-nitrophenyl)- 54799-93-8 M0048365 M0048364 T078368 S 2160 T078366 S-2160 M0048364 benzoyl-Phe-Val-Arg-p-nitroanilide C0130870 M0048365 M0048364 T078367 benzoyl-Phe-Val-Arg-p-nitroanilide T078362 Bz-Phe-Val-Arg-paranitroanilide T078365 N-benzoyl-L-phenylalanyl-L-valyl-L-arginine-p-nitroanilide T078364 N-alpha-benzoyl-L-phenylalanyl-L-valyl-L-arginine-p-nitroanilide T078363 BzPheValArgNaN C419207 FimW protein 2001 01 31 2001 2002 a negative regulator of type 1 fimbrial expression; isolated from Salmonella enterica; has been sequenced 2 *D004268 DNA-Binding Proteins J Bacteriol 2001 Jan;183(2):435-42 THA THA M0377575 FimW protein C0963656 0 T116 Amino Acid, Peptide, or Protein T434703 FimW protein 2001 01 31 T434704 fimW gene product 2001 01 31 C429529 XP 280 2001 06 26 2001 06 28 2001 2001A 2002 an integrin alphaIIbbeta2 antagonist 1 *D007555 Isoxazoles D000409 Alanine *Q000031 analogs ; derivatives J Biol Chem 2001 May 18;276(20):7063-8 THA THA THA M0391929 XP 280 C0967203 0 T116 Amino Acid, Peptide, or Protein T452433 XP 280 2001 06 26 T452436 3-(((-3-(4-(aminoiminomethyl)phenyl)-4,5-dihydro-5-isoxazolyl)acetyl)amino)-N-(butoxycarbonyl)alanine monobenzenesulfonate 2001 06 26 T452434 XP-280 2001 06 26 T452435 XP28- 2001 06 26 C092237 enterohemorrhagic Escherichia coli-HlyC protein 1995 03 27 2001 06 28 1995 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 related but not identical to alpha-hemolysin; amino acid sequence given in first source; GenBank X80891 16 *BACTERIAL PROTEINS (1995-2001) *D000217 Acyltransferases *D006460 Hemolysins D001427 Bacterial Toxins Infect Immun 1995 Mar;63(3):1055-61 PML THA THA M0243487 enterohemorrhagic Escherichia coli-HlyC protein C0294699 EC 2.3.1.- T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T126 Enzyme T273492 enterohemorrhagic Escherichia coli-HlyC protein T273489 EHEC-HlyC protein T273490 HlyC protein, EHEC T273491 hylC gene product, EHEC C419210 GrvA protein 2001 01 31 2001 2002 isolated from Gifsy-2 phage; has been sequenced; GenBank AF266469 1 *D014764 Viral Proteins J Bacteriol 2001 Jan;183(2):611-20 THA THA M0377580 GrvA protein C0963661 0 T116 Amino Acid, Peptide, or Protein T434710 GrvA protein 2001 01 31 T434711 grvA gene product 2001 01 31 C419209 lipase foldase 2001 01 31 2001 01 31 2001 2001A 2002 7 *D018832 Molecular Chaperones J Bacteriol 2001 Jan;183(2):597-603 THA THA THA M0377577 lipase foldase C0963658 0 T116 Amino Acid, Peptide, or Protein M0377577 M0377578 M0377577 M0377579 T434707 lipase foldase 2001 01 31 M0377578 Lif protein C0963659 M0377577 M0377578 T434708 Lif protein 2001 01 31 M0377579 lipH gene product C0963660 M0377577 M0377579 T434709 lipH gene product 2001 01 31 C419211 YkdA protein 2001 01 31 2001 2002 an HtrA-like protease isolated from Bacillus subtilis; base sequence in first source 1 *D012697 Serine Endopeptidases JJ Bacteriol 2000 Mar;182(6):1592-9 THA THA M0377581 YkdA protein C0963662 EC 3.4.21.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T434712 YkdA protein 2001 01 31 T434713 ykdA gene product 2001 01 31 C015516 succinyl-trialanine-4-nitroanilide 1977 01 01 2001 06 28 1999 2000 2001 2001A 2002 synthetic substrate of porcine pancreatic elastase 44 ANILIDES (77-82) *D009842 Oligopeptides Ann Clin Biochem 1979;16(6):320 Clin Chim Acta 1979;95(2):401 Clin Chim Acta 96(3):215;1979 FEBS Lett 80(1):182;1977 NLM CCR CCR M0064846 succinyl-trialanine-4-nitroanilide C0075451 L-Alaninamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-N-(4-nitrophenyl)- 52299-14-6 D002863 Chromogenic Compounds M0064846 M0064845 T094849 succinyl-trialanine-4-nitroanilide T094842 Suc-Ala(3)-NA T094839 N-succinyl-L-trialanine p-nitroanilide T094843 Suc-Ala(3)-Nan T094844 Suc-Ala-Ala-Ala-p-nitroanilide T094845 succinyl-alanyl-alanyl-alanine-p-nitroanilide T094846 succinyl-trialanine-p-nitroanilide T094847 succinyltrialanine-p-nitroanilide T094837 3-carboxypropionyl-alanyl-alanyl-alanyl-4-nitroanilide T094838 3-carboxypropionyl-trialanine-p-nitroanilide T094840 SANA T094841 SLAPN M0064845 trianiline-4-nitroanilide C0146628 M0064846 M0064845 T094848 trianiline-4-nitroanilide C006202 fluazacort 1974 01 01 2001 08 01 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 OXAZOLES (74-82) *D011244 Pregnadienediols Arzneim Forsch 25(10):1650;1975 G Batteriol Virol Immunol 70(1-6):95;1977 Hautarzt 24(12):555;1974 NLM TWD TWD M0048485 fluazacort C0060474 5'H-pregna-1,4-dieno(17,16-d)oxazole-3,20-dione, 21-(acetyloxy)-9-fluoro-11-hydroxy-2'-methyl-, (11 beta,16 beta)- 19888-56-3 M0048485 M0048484 M0048485 M0048483 T078488 fluazacort Negwer, 5th ed, #5398 UD 23:63f USAN (1980) T078485 9 alpha-fluoro-11 beta,21-dihydroxy-3,20-dioxo-1,4-pregnadieno(17 alpha,16 alpha-d)-2-methyloxazoline 21-acetate M0048484 Azacortid C0104790 M0048485 M0048484 T078487 Azacortid M0048483 L-6400 C0124901 M0048485 M0048483 T078486 L-6400 C015681 anidoxime 1978 01 01 2001 08 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure given in second source 1 *OXIMES (80-83) *D011427 Propiophenones Br J Anesthesiol 49:257;1977 J Pharm Sci 1980;69(2):225 NLM TWD TWD M0065155 anidoxime C0051907 O-(4-methoxyphenylcarboxyl)-3-diethylaminiopropiophenone oxime 34297-34-2 31729-11-0 (HCl) M0065155 M0312921 T095158 anidoxime T095157 O-(4-methoxyphenylcarbamoyl)-3-diethylaminopropiophenone oxime T095156 4-MPC-3-DAPO M0312921 anidoxime hydrochloride C0952780 31729-11-0 M0065155 M0312921 T342921 anidoxime hydrochloride 1999 08 18 C006230 ORF 8511 1974 01 01 2001 01 30 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *CYCLOHEXANOLS (74-80) D003506 Cyclofenil *Q000031 analogs ; derivatives Contraception 9(4):393;1974 NLM TWD TWD M0048558 ORF 8511 C0602579 cyclohexanol, 4-(diphenylmethylene)-2-ethyl-3-methyl-, acetate 52236-34-7 M0048558 M0048557 T078561 ORF 8511 UD 25:71k M0048557 1-(diphenylmethylenyl)-2-methyl-3-ethyl-4-acetoxycyclohexane C0602578 M0048558 M0048557 T078560 1-(diphenylmethylenyl)-2-methyl-3-ethyl-4-acetoxycyclohexane C006151 R 1342 1974 01 01 1996 09 16 1997 1998 1999 2000 2001 2002 appetite stimulant; structure 0 OXIMES (74-82) *D010627 Phenethylamines Naturwissenschaften 60(9):432;1973 NLM PML BVL M0048332 R 1342 C0602506 N,alpha,4-trihydroxybenzeneethanimidamide 50602-45-4 T078335 R 1342 C006226 4-bromotetramisole 1974 01 01 2000 07 31 2001 2002 available in levo ; dextro form; L-form potent inhibitor of non specific alkaline phosphatase; RN given refers to cpd without isomeric designation 34 *THIAZOLES (74-76) IMIDAZOLES (74-76) D013773 Tetramisole *Q000031 analogs ; derivatives D007978 Levamisole Q000031 analogs ; derivatives Acta Odontol Scand 33(3):143;1976 Biochem Pharmacol 24:1175;1975 Clin Chem 23(3):454;1977 Experientia 33(2):154;1977 Histochemistry 44(3):277;1975 Infect Immun 23(1):94;1979 J Clin Chem Clin Biochem 1979;17(9):605 J Histochem Cytochem 21(9):812;1973 J Histochem Cytochem 26(5):359;1978 NLM TWD sjn M0048547 4-bromotetramisole C0048142 6646-46-4 T109 Organic Chemical T121 Pharmacologic Substance D000871 Anthelmintics 56943-06-7 ((S)-isomer) 62284-79-1 (oxalate[1:1] salt(S)-isomer) M0048547 M0309501 M0048547 M0309502 T078550 4-bromotetramisole Negwer, 5th ed, #1508 T078549 p-bromotetramisole T078545 1-(para-bromotetramisole) T078546 6-bromolevamisole T078547 D-4-bromotetramisole T078548 L-4-bromotetramisole M0309501 4-bromotetramisole, (S)-isomer C0895038 56943-06-7 T109 Organic Chemical T121 Pharmacologic Substance M0048547 M0309501 T339501 4-bromotetramisole, (S)-isomer 1999 08 18 M0309502 4-bromotetramisole, oxalate (1:1), salt(S)-isomer C0895039 62284-79-1 T109 Organic Chemical T121 Pharmacologic Substance M0048547 M0309502 T339502 4-bromotetramisole, oxalate (1:1), salt(S)-isomer 1999 08 18 C003544 cortol 1972 01 01 2000 07 31 2001 2002 RN given refers to (3alpha,5beta,11beta,20S)-isomer 4 HYDROXYCORTICOSTEROIDS (72-80) *D011278 Pregnanes Endokrinologie 1979;74(2):158 NLM CCR sjn M0044580 cortol C0056397 5 beta-pregnane-3 alpha,11 beta,17,20,21-pentol 516-38-1 T110 Steroid 22630-70-2 ((3beta,5beta,11beta,20R)-isomer) 3638-91-3 ((3alpha,5alpha,11beta,20S)-isomer) 516-39-2 ((3beta,5alpha,11beta,20R)-isomer) 667-65-2 ((3alpha,5beta,11beta,20R)-isomer) 78184-96-0 ((11beta)-isomer) M0044580 M0308316 M0044580 M0308313 M0044580 M0308315 M0044580 M0308314 M0044580 M0308312 T074583 cortol Merck Index, 9th ed, p. 329, #2518 M0308316 cortol, (11beta)-isomer C0894453 78184-96-0 T110 Steroid M0044580 M0308316 T338316 cortol, (11beta)-isomer 1999 08 18 M0308313 cortol, (3alpha,5alpha,11beta,20S)-isomer C0894451 3638-91-3 T110 Steroid M0044580 M0308313 T338313 cortol, (3alpha,5alpha,11beta,20S)-isomer 1999 08 18 M0308315 cortol, (3alpha,5beta,11beta,20R)-isomer C0917123 667-65-2 T110 Steroid M0044580 M0308315 T338315 cortol, (3alpha,5beta,11beta,20R)-isomer 1999 08 18 M0308314 cortol, (3beta,5alpha,11beta,20R)-isomer C0894452 516-39-2 T110 Steroid M0044580 M0308314 T338314 cortol, (3beta,5alpha,11beta,20R)-isomer 1999 08 18 M0308312 cortol, (3beta,5beta,11beta,20R)-isomer C0894450 22630-70-2 T110 Steroid M0044580 M0308312 T338312 cortol, (3beta,5beta,11beta,20R)-isomer 1999 08 18 C431783 RPR 200765A 2001 08 02 2001 2002 a p38 MAP kinase inhibitor; structure in first source 1 *D007093 Imidazoles Bioorg Med Chem 2001 Feb;9(2):537-54 SZM SZM M0394659 RPR 200765A C0968213 0 T109 Organic Chemical T121 Pharmacologic Substance T456110 RPR 200765A 2001 08 02 T456111 RPR-200765 A 2001 08 02 C030848 (4'-ethyl-2-methyl-3-piperidino)propiophenone 1981 08 06 2001 08 02 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 39 *D011427 Propiophenones No To Shinkei 1981;33(3):237 RLS TWD TWD M0097328 (4'-ethyl-2-methyl-3-piperidino)propiophenone C0043606 1-Propanone, 1-(4-ethylphenyl)-2-methyl-3-(1-piperidinyl)-, hydrochloride 56839-43-1 D000927 Anticonvulsants D002121 Calcium Channel Blockers D009125 Muscle Relaxants, Central D010276 Parasympatholytics D014665 Vasodilator Agents M0097328 M0097326 T127332 (4'-ethyl-2-methyl-3-piperidino)propiophenone USAN 1986, p. 448 T127329 4-EMPP T127331 eperisone M0097326 E-0646 C0115285 M0097328 M0097326 T127330 E-0646 C006170 dactylarin 1974 01 01 1990 03 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 isolated from Dactylaria lutea (Deuteromycetes); structure 2 ANISOLES (74-78) *D001572 Benzofurans Cancer Res 1979;39(10):4242 J Antibiotics 26(11):692;1973 NLM TBT NLM M0048383 dactylarin C0057086 3,7-dihydroxy-2',5-dimethoxy-6'-methylspiro(benzofuran-2(3H),1'-(2,5)CYCLOHEXADIEN)-4'-ONE 52212-96-1 T078386 dactylarin C034349 metamfepramone 1982 05 24 2001 08 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd 5 *D011427 Propiophenones Fortschr Med 1982; 100(7):289 RLS TWD TWD M0105922 metamfepramone C0066048 15351-09-4 T135926 metamfepramone Merck Index, 9th ed, #5775 Negwer, 5th ed, #1678 USAN 1982, p.290 T135923 2-(dimethylamino)propiophenone T135924 dimepropion T135925 dimethylpropion C064816 kinetoplast-associated protein 1990 08 07 2001 08 02 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2001B 2002 amino acid sequence given in first source; expressed in the kinetoplasts of epimastigotes ; amastigotes 5 *D015800 Protozoan Proteins D014349 Trypanosoma cruzi D018320 Leishmania major Mol Biochem Parasitol 1990;40(2):233 TPW jmp jmp M0178417 kinetoplast-associated protein C0641870 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T208422 kinetoplast-associated protein T456112 KAP proteins, protozoan 2001 08 02 C076106 vps35 protein 1992 09 11 2001 01 31 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2001B 2002 amino acid sequence given in first source; involved in sorting of vacuolar proteins 8 *FUNGAL PROTEINS (1992-2000) *D002352 Carrier Proteins *D008565 Membrane Proteins D012441 Saccharomyces cerevisiae Mol Biol Cell 1992 Apr;3(4):415-27 BXB WXM WXM M0204800 vps35 protein C0653181 149769-26-6 T234805 vps35 protein T234804 vps35 gene product C095395 CVD 112 1995 10 02 2000 07 31 2001 2002 a vaccine for Vibrio cholera O139 2 *BACTERIAL VACCINES (1996-2000) *D022121 Cholera Vaccines J Infect Dis 1995 Sep;172(3):883-6 PML nns sjn M0251219 CVD 112 C0380992 0 T121 Pharmacologic Substance T129 Immunologic Factor T281224 CVD 112 T281223 CVD-112 C050745 4-hydroxyaminopropiophenone 1986 12 16 2001 08 02 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 4 *D011427 Propiophenones Hum Toxicol 1986;5(5):295 MEG TWD TWD M0144732 4-hydroxyaminopropiophenone C0048315 55-34-5 T174737 4-hydroxyaminopropiophenone T174734 4-hydroxylaminopropiophenone T174736 p-hydroxylaminopropiophenone T174735 PHAPP C411197 1-oxo-4,9-dihydroxy-8-methoxy-6-hydroxymethyl-1,2,3,4-tetrahydroanthracene 2000 07 26 2000 2001 2002 from Eremurus chinensis; structure in first source 1 *D000873 Anthracenes J Nat Prod 2000 May;63(5):653-6 BMB BMB M0366649 1-oxo-4,9-dihydroxy-8-methoxy-6-hydroxymethyl-1,2,3,4-tetrahydroanthracene C0915923 0 T109 Organic Chemical T419997 1-oxo-4,9-dihydroxy-8-methoxy-6-hydroxymethyl-1,2,3,4-tetrahydroanthracene 2000 07 26 T419998 1-ODMHTA 2000 07 26 C006209 DWP 7055 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 chlorinated homologs of oxybenzol 0 *D002722 Chlorobenzenes Czas Stomatol 27(11):1173;1974 NLM NLM M0048503 DWP 7055 C0602546 0 T078506 DWP 7055 C076107 tra-2 protein, Caenorhabditis elegans 1992 09 11 2001 01 31 1997 1998 1999 2000 2001 2001A 2002 Tra-2 - Transformer-2; a sex-determining gene product; amino acid sequence given in first source 9 *D008565 Membrane Proteins *D015801 Helminth Proteins Mol Biol Cell 1992 Apr;3(4):461-73 BXB WXM WXM M0204802 tra-2 protein, Caenorhabditis elegans C0653183 147478-40-8 T234807 tra-2 protein, Caenorhabditis elegans T234806 tra-2 gene product, C. elegans C076138 Hox 3.6 protein 1992 09 16 2001 01 31 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a murine homeobox gene located in the 5' region of the Hox-3 cluster; amino acid sequence given in first source 2 *DNA-BINDING PROTEINS (92-95) *D018398 Homeodomain Proteins Mech Dev 1992 May;37(3):151-66 BXB WXM WXM M0204882 Hox 3.6 protein C0171237 149023-43-8 T234887 Hox 3.6 protein T234886 Hox-3.6 protein C076157 high-iron diamine-thiocarbohydrazide-silver proteinate 1992 09 17 2001 01 31 1998 1999 2000 2001 2001A 2002 combination of high-iron diamine, thiocarbohydrazide and silver proteinate; used in microscopy 4 *D006834 Hydrazines *D012836 Silver Proteins J Histochem Cytochem 1992 Sep;40(9):1257-67 BXB WXM WXM M0204918 high-iron diamine-thiocarbohydrazide-silver proteinate C0653243 0 T234923 high-iron diamine-thiocarbohydrazide-silver proteinate T234922 HID-TCH-SP C006224 janiemycin 1974 01 01 1993 05 03 1994 1995 1996 1997 1998 1999 2000 2001 2002 basic peptide from Streptomyces macrosporeus ATCC 21388; related to enduracidin; gram-positive 0 PEPTIDES (74-93) *D017561 Antibiotics, Peptide Antimicrob Agents Chemother 4(3):231;1973 NLM BXB TPW M0048538 janiemycin C0602565 50646-98-5 T078541 janiemycin UD 23:82b C006248 Wy 12157 1974 01 01 2001 08 22 1998 1999 2000 2001 2001A 2002 RN ; N1 refer to mono-HCl 0 INDOLIZINES (74-82) *D007211 Indoles J Pharm Sci 63(5):787;1974 NLM WXM WXM M0048621 Wy 12157 C0602607 1H-indolizino(8,7-b)indole, 2,3,5,6,11,11b-hexahydro-11,11b-dimethyl-, monohydrochloride 33621-13-5 M0048621 M0048618 T078624 Wy 12157 UD 23:50q T078623 Wy-12157 T078622 Wy-12,157 M0048618 2,3,5,6,11,11b-hexahydro-11,11b-dimethyl-14-indolizino(8,7-b)indole hydrochloride C0950234 M0048621 M0048618 T078621 2,3,5,6,11,11b-hexahydro-11,11b-dimethyl-14-indolizino(8,7-b)indole hydrochloride C006379 N-acetylmethionine 1975 01 01 2000 07 31 2001 2002 RN given refers to L-isomer 37 D008715 Methionine *Q000031 analogs ; derivatives Adv Exp Med Biol 105:571;1978 J Agric Food Chem 1979;27(6):1286 J Nutr 109(6):970;1979 J Nuytr 1980;110(1):42 Med Welt 26(51):2305;1975 Z Allgemein Med 51(18):837;1975 NLM TWD sjn M0048891 N-acetylmethionine C0067748 65-82-7 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance 1115-47-5 ((DL)-isomer) 1509-92-8 ((D)-isomer) 70461-66-4 (mono-Na salt) 80440-53-5 (mono-K salt) M0048891 M0309542 M0048891 M0309541 M0048891 M0048890 M0048891 M0309544 M0048891 M0309543 T078894 N-acetylmethionine Ippen Index Pharm 9M 5.5.1 M0309542 N-acetylmethionine, (D)-isomer C0895078 1509-92-8 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance M0048891 M0309542 T339542 N-acetylmethionine, (D)-isomer 1999 08 18 M0309541 N-acetylmethionine, (DL)-isomer C0917140 1115-47-5 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance M0048891 M0309541 T339541 N-acetylmethionine, (DL)-isomer 1999 08 18 M0048890 Hepsan C0121493 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance M0048891 M0048890 T078893 Hepsan M0309544 N-acetylmethionine monopotassium salt C0895080 80440-53-5 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance M0048891 M0309544 T339544 N-acetylmethionine monopotassium salt 1999 08 18 M0309543 N-acetylmethionine monosodium salt C0895079 70461-66-4 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance M0048891 M0309543 T339543 N-acetylmethionine monosodium salt 1999 08 18 C029491 insulin, 3-iodo-Tyr(A14)- 1981 05 28 2001 08 23 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 used with (125)I for receptor assay 23 D007328 Insulin *Q000031 analogs ; derivatives D007457 Iodine Radioisotopes J Biol Chem 1981;256(8):4042 RLS CCR CCR M0094051 insulin, 3-iodo-Tyr(A14)- C0063652 51798-73-3 T124054 insulin, 3-iodo-Tyr(A14)- T124051 A14-3-iodo-Tyr-insulin T124052 A14-3-iodotyrosine-insulin T124053 insulin, 3-iodotyrosine(A14)- C003545 cortolone 1974 01 01 2000 07 31 2001 2002 RN given refers to (3alpha,5beta,20S)-isomer 9 HYDROXYCORTICOSTEROIDS(74-80) KETOSTEROIDS (74-76) *D011278 Pregnanes Endokrinologie 1979;74(2):158 NLM CCR sjn M0044581 cortolone C0056399 3 alpha,17 alpha,20 alpha,21-tetrahydroxy-5 beta- pregnan-11-one 516-42-7 T110 Steroid 640-85-7 ((3alpha,5alpha,20S)-isomer) 667-66-3 ((3alpha,5beta,20R)-isomer) M0044581 M0308317 M0044581 M0308318 T074584 cortolone Merck Index, 9th ed, p. 328, #2519 M0308317 cortolone, (3alpha,5alpha,20S)-isomer C0894454 640-85-7 T110 Steroid M0044581 M0308317 T338317 cortolone, (3alpha,5alpha,20S)-isomer 1999 08 18 M0308318 cortolone, (3alpha,5beta,20R)-isomer C0894455 667-66-3 T110 Steroid M0044581 M0308318 T338318 cortolone, (3alpha,5beta,20R)-isomer 1999 08 18 C006270 avridine 1974 01 01 2001 02 02 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd 63 *PROPYLAMINES (74-78) *D003959 Diamines Arthr Rheumat 21(1):169;1978 Arthritis Rheum 1980;23(1):62 Comprehensive Ther 3(7):25;1977 Infection Immun 9(3):506;1974 J Reticuloendothel Soc 1979;26(Suppl):655 J Reticuloendothel Soc 1979;26(Suppl):667 N. Engl. J. Med 291(2):57;1974 Texas Rep Biol Med 35:528;1978 NLM CCR CCR M0048700 avridine C0104737 N,N-dioctadecyl-N',N'-bis(2-hydroxyethyl)propanediamine 35607-20-6 T109 Organic Chemical T121 Pharmacologic Substance D000276 Adjuvants, Immunologic D000998 Antiviral Agents D007369 Interferon Inducers 37511-08-3 (phosphate[2:1] salt) M0048700 M0048701 M0048700 M0309518 T078703 avridine T078702 N,N-dioctyldecyl-N',N-bis(2-hydroxyethyl)propanediamine M0048701 CP 20961 C0110844 T109 Organic Chemical T121 Pharmacologic Substance M0048700 M0048701 T078704 CP 20961 T078700 CP 20,961 T078701 CP-20,961 M0309518 avridine phosphate (2:1) C0951510 37511-08-3 T109 Organic Chemical T121 Pharmacologic Substance M0048700 M0309518 T339518 avridine phosphate (2:1) 1999 08 18 C029788 insulin, Trp(B1)- 1981 06 12 2001 08 23 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 Trp replacement of B1 Phe in bovine ; porcine insulins 2 D007328 Insulin *Q000031 analogs ; derivatives Sci Sin 1980:23(11):1443 MEG CCR CCR M0094786 insulin, Trp(B1)- C0063666 0 T124789 insulin, Trp(B1)- T124788 insulin, tryptophan(B1)- T124786 B1-Trp-insulin T124787 B1-tryptophan-insulin C006321 cinpropazide 1974 01 01 2001 04 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 potent vasodilator exerting principal action on intramyocardial circulation increasing the blood flow of the coronary vessels ; of the endocardic microcirculation; structure 2 CINNAMATES (74-82) *D010879 Piperazines Ann Pharm Francais 33(6-7):301;1975 Therapie 29(2):233;1974 NLM CCR CCR M0048837 cinpropazide C0055770 26328-00-7 M0048837 M0048836 T078840 cinpropazide T078838 1-(3',4',5'-trimethoxycinnamoyl)-4-(N-isopropylaminocarbonylmethyl)piperazine maleate M0048836 MD 68111 C0127212 M0048837 M0048836 T078839 MD 68111 C030057 insulin, Asn(B12)- 1981 06 26 2001 08 23 1998 1999 2000 2001 2001A 2002 human insulin; valine is replaced by asparagine at position B12; RN given refers to ion(2-) 1 D007328 Insulin *Q000031 analogs ; derivatives Int J Pept Protein Res 1981;17(2):243 MEG CCR CCR M0095397 insulin, Asn(B12)- C0613284 Insulin, 12-L-asparagine-30-L-threonine-, 7,19-bis(hydrogen sulfate), ion(2-) 78212-36-9 T125401 insulin, Asn(B12)- T125398 B12-Asn-insulin T125399 B12-asparagine-insulin T125400 insulin, asparagine(B12)- C030314 insulin, Leu(B30)- 1981 07 10 2001 08 23 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 semisynthetic insulin with Leu in the B30 position; has less immunoreactivity than other B30 position insulin analogs; has full activity in receptor binding ; biological effects 2 D007328 Insulin *Q000031 analogs ; derivatives Diabetes 1981;30(6):519 RLS CCR CCR M0095970 insulin, Leu(B30)- C0063655 92679-50-0 T125974 insulin, Leu(B30)- T125971 B30-Leu-insulin T125972 B30-leucine-insulin T125973 insulin, leucine(B30)- C031207 insulin, Leu(B24,B25)- 1981 08 19 2001 08 23 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 leucine was substituted at position B24 ; B25 in insulin chain 1 D007328 Insulin *Q000031 analogs ; derivatives Hoppe Seylers Z Physiol Chem 1981;362(5):557 MGR CCR CCR M0098247 insulin, Leu(B24,B25)- C0614076 0 T128251 insulin, Leu(B24,B25)- T128248 B24,B25-Leu-insulin T128249 B24,B25-leucine-insulin T128250 insulin, leucine (B24,B25)- C070672 DAC 5945 1991 10 02 2001 04 30 1995 1996 1997 1998 1999 2000 2001 2001A 2002 3 *D010879 Piperazines KLN CCR CCR M0192318 DAC 5945 C0287296 1-Piperazineethanol, alpha-cyclohexyl-4-(iminomethyl)-alpha-phenyl-, monohydrochloride 124065-13-0 M0192318 M0192317 T222323 DAC 5945 T222321 DAC-5945 M0192317 N-iminomethyl-N'-((2-hydroxy-2-phenyl-2-cyclohexyl)ethyl)piperazine hydrochloride C0950798 M0192318 M0192317 T222322 N-iminomethyl-N'-((2-hydroxy-2-phenyl-2-cyclohexyl)ethyl)piperazine hydrochloride C072978 R 73335 1992 03 20 2001 04 30 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 inhibitor of adenosine flux 1 *D010879 Piperazines Adv Exp Med Biol 1991;309A:415-8 BXB CCR CCR M0197450 R 73335 C0649836 1-Piperazineacetamide, 2-(aminocarbonyl)-4-(5,5-bis(4-fluorophenyl)pentyl)-N-(3-chloro-2,5,6,7-tetrahydro-2-oxo-1H-1-pyrindin-4-yl)- 120785-90-2 M0197450 M0197448 T227455 R 73335 T227454 R-73335 M0197448 2-(aminocarbonyl)-4-(5,5-bis(4-fluorophenyl)pentyl)-N-(3-chloro-2,5,6,7-tetrahydro-2-oxo-1H-pyridin-4-yl)-1-piperazine acetamide C0649834 M0197450 M0197448 T227453 2-(aminocarbonyl)-4-(5,5-bis(4-fluorophenyl)pentyl)-N-(3-chloro-2,5,6,7-tetrahydro-2-oxo-1H-pyridin-4-yl)-1-piperazine acetamide C046114 CLS 2210 1985 08 30 2000 12 21 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 benzenesulfonate derivative which cleans cardiac lymph vessels better tha hyaluronidase; thereby reduces the size of myocardial infarcts after coronary occlusion 6 *D001557 Benzenesulfonates Angiology 1985;36(7):452 RLS TWD TWD M0133774 CLS 2210 C0055965 CLS 2210 99270-13-0 T109 Organic Chemical T121 Pharmacologic Substance T163779 CLS 2210 T163778 CLS-2210 C046065 4,4'-(carbonylbis(benzene-4,1-diyl)bis(imino))bis(benzene sulfonate) sodium salt 1985 08 22 2001 02 02 1997 1998 1999 2000 2001 2001A 2002 fluorochrome from aniline blue 3 *D001557 Benzenesulfonates Stain Technol 1985;60(3):155 RLS TWD TWD M0133633 4,4'-(carbonylbis(benzene-4,1-diyl)bis(imino))bis(benzene sulfonate) sodium salt C0096212 Benzenesulfonic acid, 4,4'-(carbonylbis(4,1-phenyleneimino))bis- 85137-47-9 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0133633 M0133634 T163638 4,4'-(carbonylbis(benzene-4,1-diyl)bis(imino))bis(benzene sulfonate) sodium salt M0133634 Sirofluor C0142362 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0133633 M0133634 T163639 Sirofluor C006293 F 30385 1974 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *D009581 Nitrofurans Chinese Med J 1:40;1974 NLM TWD TWD M0048759 F 30385 C0602653 3830-11-3 T078762 F 30385 T078761 F-30385 C002114 Histaglobin 1973 01 01 2001 02 02 1998 1999 2000 2001 2001A 2002 drug combination of histamine ; gamma globulin; see also histaglobulin 17 *D005719 Gamma-Globulins *D006632 Histamine D004338 Drug Combinations D001249 Asthma Q000188 drug therapy Fiziol Ah 22(3):357;1976 Pediatr Akush Ginekol 1:18;1977 Probl Tuberk 2:47;1976 Srp Arh Celok Lek 1979;107(5):477 Vestn Otorinolaringol 3:26;1979 Z Erkr Atmungsorgane 136(3):337;1972 NLM CCR CCR M0042592 Histaglobin C0062737 1H-Imidazole-4-ethanamine, dihydrochloride, mixt. with gamma-globulins 37317-09-2 T109 Organic Chemical T121 Pharmacologic Substance T072595 Histaglobin C073650 S 14671 1992 04 20 2001 04 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 serotonin receptor agonist; RN from toxlit 6 *D010879 Piperazines *D013876 Thiophenes Eur J Pharmacol 1991 Oct 15;203(2):319-22 RLS CCR CCR M0199038 S 14671 C0166353 135722-27-9 M0199038 M0199036 T229043 S 14671 T229042 S-14671 M0199036 4-((thenoyl)-2-aminoethyl)-1-(7-methoxynaphthylpiperazine) C0166352 M0199038 M0199036 T229041 4-((thenoyl)-2-aminoethyl)-1-(7-methoxynaphthylpiperazine) C076312 dithiobis(N,N-dimethyl-4-acetylpiperazinium) 1992 09 24 2001 04 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source; stimulates nicotinic receptors in the chick retina; blocks binding to neuronal bungarotoxin to retinal homogenates; RN refers to the diiodide cpd 1 *D010879 Piperazines D011978 Receptors, Nicotinic Mol Pharmacol 1992 Aug;42(2):356-63 THA CCR CCR M0205305 dithiobis(N,N-dimethyl-4-acetylpiperazinium) C0653413 145707-16-0 M0205305 M0205304 T235310 dithiobis(N,N-dimethyl-4-acetylpiperazinium) T235308 DT-DMAP M0205304 dithiobis(N,N-dimethyl-4-acetylpiperazinium), diiodide C0653412 M0205305 M0205304 T235309 dithiobis(N,N-dimethyl-4-acetylpiperazinium), diiodide C076232 HAL1 protein 1992 09 21 2001 01 31 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; a novel conserved salt-induced protein; an important determinant of salt tolerance in yeast 11 *D005656 Fungal Proteins EMBO J 1992 Sep;11(9):3157-64 BXB WXM WXM M0205118 HAL1 protein C0527271 148349-03-5 T235123 HAL1 protein T235122 HAL1 gene product C076234 PRP38 protein 1992 09 21 2001 01 31 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; an essential pre-mRNA splicing factor; appears to interact with U6 snRNA 3 *D005656 Fungal Proteins D012326 RNA Splicing Mol Cell Biol 1992 Sep;12(9):3939-47 THA WXM WXM M0205124 PRP38 protein C0653331 148294-68-2 T235129 PRP38 protein T235128 PRP38 gene product C076235 DPH5 protein 1992 09 21 2001 01 31 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; shows sequence similarity to bacterial AdoMet-uroporphyrinogen III methyltransferases; required for diphthalamide synthesis in Saccharomyces cerevisiae 1 *D008780 Methyltransferases Mol Cell Biol 1992 Sep;12(9):4026-37 THA WXM WXM M0205126 DPH5 protein C0653333 EC 2.1.1.- T235131 DPH5 protein T235130 DPH5 gene product C077079 4-methylpiperazine-2,6-dione 1992 11 02 2001 04 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 2 *D010879 Piperazines Pharm Res 1992 Sep;9(9):1209-14 BXB CCR CCR M0207130 4-methylpiperazine-2,6-dione C0173095 2,6-Piperazinedione, 4-methyl- 60725-35-1 T237135 4-methylpiperazine-2,6-dione T237134 4-methyl-2,6-piperazinedione T237133 4-MP C006309 BRL 51242 1974 01 01 2001 08 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *IMIDAZOLES (74-82) *D014226 Triazenes Cancer Chemother Rep 57(3):263;1973 NLM CCR CCR M0048812 BRL 51242 C0602664 37126-45-7 M0048812 M0048809 M0048812 M0048811 T078815 BRL 51242 T078813 BRL-51242 M0048809 4-carbethoxy-5-(3,3-dimethyl-1-triazeno)-2-phenylimidazole C0602661 M0048812 M0048809 T078812 4-carbethoxy-5-(3,3-dimethyl-1-triazeno)-2-phenylimidazole M0048811 NSC 166721 C0602663 M0048812 M0048811 T078814 NSC 166721 C006294 Abbott 31699 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D013844 Thiazoles J Med Chem 16(10):1157;1973 NLM NLM M0048760 Abbott 31699 C0050354 5-(p-hydroxyanilino)-1,2,3,4-thiatriazole 23567-67-1 T078763 Abbott 31699 C006308 methodichlorophen 1974 01 01 2001 07 17 1997 1998 1999 2000 2001 2001A 2002 histamine methyltransferase antagonist 79 *PYRIMIDINES (74-78) D011739 Pyrimethamine *Q000031 analogs ; derivatives Adv Enzyme Regul 1978;17 Biochem Pharmacol 26(6):543;1977 Br J Cancer 28(3):263;1973 Br Med J 2(5961):20;1975 Cancer 40(Suppl 1):519;1977 Cancer Chemother Pharmacol 1(2):101;1978 Cancer Res 1979;39(9):3441 Cancer Res 1979;39(9):3612 Cancer Treat Rep 61(4):559;1977 Cancer Treat Rep 62(3):341;1978 Cancer Treat Rep 62(5):849;1978 Clin Oncol 3:281;1977 Clin Oncol 5(1):11;1979 Drug Metab Dispos 6(3):329;1978 Eur J Cancer 13:861;1977 Eur J Cancer 1980;16(1):147 Exp Hematol 4:43;1976 J Chromatogr 137(2):449;1977 J Chromatogr 156(1):181;1978 J Clin Pathol 30:1154;1977 Lancet 2(8038):607;1977 Mol Pharmacol 1979;16(2):607 NLM CCR CCR M0048808 methodichlorophen C0066142 7761-45-7 D000970 Antineoplastic Agents D004791 Enzyme Inhibitors D005493 Folic Acid Antagonists 59921-68-5 (HCl) M0048808 M0048804 M0048808 M0048805 M0048808 M0309528 T078811 methodichlorophen T078806 2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine T078809 DDMP T078810 metoprine M0048804 BW 1970 C0107581 M0048808 M0048804 T078807 BW 1970 M0048805 BW 50,197 C0107584 M0048808 M0048805 T078808 BW 50,197 M0309528 methodichlorophen hydrochloride C0969909 59921-68-5 M0048808 M0309528 T339528 methodichlorophen hydrochloride 1999 08 18 C430883 BIN3 protein, F-actin localization 2001 07 17 2001 2002 regulates F-actin localization; GenBank AF2717232; do not confuse with Bin3 protein 1 *D008840 Microfilament Proteins J Biol Chem 2001 Jun 15;276(24):21670-7 THA THA M0393550 BIN3 protein, F-actin localization C0967772 0 T116 Amino Acid, Peptide, or Protein T454496 BIN3 protein, F-actin localization 2001 07 17 T454497 BIN3 gene product 2001 07 17 T454498 bridging integrator-3 2001 07 17 C430884 protein kinase C-associated kinase 2001 07 17 2001 2002 possesses ankyrin repeats; GenBank AF302127 1 *D011494 Protein Kinases D008565 Membrane Proteins D017487 Ankyrins J Biol Chem 2001 Jun 15;276(24):21737-44 THA THA M0393551 protein kinase C-associated kinase C0967773 EC 2.7.1.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T454499 protein kinase C-associated kinase 2001 07 17 T454500 PKK protein 2001 07 17 C430885 PTEN 2 protein 2001 07 17 2001 2002 a testis-specific phospholipid phosphatase found in the Golgi apparatus; amino acid sequence in first source 7 *D010744 Phosphoric Monoester Hydrolases J Biol Chem 2001 Jun 15;276(24):21745-53 THA THA M0393552 PTEN 2 protein C0967774 EC 3.1.5.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T454501 PTEN 2 protein 2001 07 17 T454502 PTEN 2 gene product 2001 07 17 C047625 thymidyl 3'-(4-nitrophenyl)phosphorothioate 1986 02 13 2001 08 20 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source; RN given is for (R)-isomer 1 D013938 Thymidine Monophosphate *Q000031 analogs ; derivatives J Biol Chem 1986;261(2):592 RLS TWD TWD M0137449 thymidyl 3'-(4-nitrophenyl)phosphorothioate C0626266 76756-12-2 76756-13-3 ((S)-isomer) M0137449 M0322623 T167454 thymidyl 3'-(4-nitrophenyl)phosphorothioate T167452 5'-deoxy-5'-thymidine-3'-(4-nitrophenyl)phosphorothioate T167453 TNPPT M0322623 thymidyl 3'-(4-nitrophenyl)phosphorothioate, (S)-isomer C0970570 76756-13-3 M0137449 M0322623 T352623 thymidyl 3'-(4-nitrophenyl)phosphorothioate, (S)-isomer 1999 08 18 C036461 J 2644 1982 12 29 2001 08 20 1996 1997 1998 1999 2000 2001 2001A 2002 4 *D010636 Phenols J Econ Entomol 1982;75(5):877 RLS CCR CCR M0111057 J 2644 C0064127 71712-03-3 M0111057 M0111054 T141061 J 2644 T141059 J-2644 T141060 J2644 M0111054 2,4-bis(1,1-dimethylethyl)-6-(4-methoxyphenylmethyl)phenol C0091535 M0111057 M0111054 T141058 2,4-bis(1,1-dimethylethyl)-6-(4-methoxyphenylmethyl)phenol C006322 compound 70-352 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D001567 Benzocycloheptenes Jap J Pharmacol 24(1):5;1974 NLM NLM M0048838 compound 70-352 C0602677 cis-2,3-dihydroxy-6 amino-6,7,8,9-tetrahydro-5-H- benzocyclohepten-5-ol HCl 52079-42-2 T078841 compound 70-352 C006324 Ro 7-4632 1974 01 01 1986 07 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CYCLOHEXANECARBOXYLIC ACIDS (74-82) *D007211 Indoles Clin Pharm Ther 16(1)(part 2):176;1974 NLM THA NLM M0048841 Ro 7-4632 C0602678 56573-69-4 T078844 Ro 7-4632 C430886 MACROH2A2 protein 2001 07 17 2001 2002 a member of the MACROH2A core histone family; GenBank AF151534 1 *D006657 Histones J Biol Chem 2001 Jun 15;276(24):21776-84 THA THA M0393553 MACROH2A2 protein C0967775 0 T116 Amino Acid, Peptide, or Protein T454503 MACROH2A2 protein 2001 07 17 T454504 MACROH2A2 gene product 2001 07 17 C006399 Actifed 1974 01 01 2001 02 02 1996 1997 1998 1999 2000 2001 2001A 2002 combination antihistaminic of triprolidine ; pseudoephedrine 21 *D004809 Ephedrine *D014311 Triprolidine D004338 Drug Combinations NLM CCR CCR M0048940 Actifed C0050631 8054-27-1 T109 Organic Chemical T121 Pharmacologic Substance D005100 Expectorants D006634 Histamine H1 Antagonists M0048940 M0048938 M0048940 M0048939 T078943 Actifed M0048938 Rinasek C0376782 T109 Organic Chemical T121 Pharmacologic Substance M0048940 M0048938 T078941 Rinasek M0048939 Trifed C0146727 T109 Organic Chemical T121 Pharmacologic Substance M0048940 M0048939 T078942 Trifed C006329 MJ 9465-2 1974 01 01 1997 08 14 1998 1999 2000 2001 2002 antidiuretic; structure 0 *D007093 Imidazoles D004231 Diuresis Q000187 drug effects Proc Soc Exptl Biol Med 144(1):203;1973 NLM MLH TPW M0048849 MJ 9465-2 C0066628 2-amino-4-(4-chlorophenyl)-2-imidazoline.HBr 40658-97-7 T078852 MJ 9465-2 C006357 acetergamine 1974 01 01 1991 07 10 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 novel uterotonic deriv of lysergamine; structure 0 *D004877 Ergoloid Mesylates Minerva Ginecol 24(3):133;1972 NLM IDX TPW M0048855 acetergamine C0602682 (+)-N-acetyl-9,10-dihydrolysergamine 3031-48-9 T078858 acetergamine Negwer, #3086 C031822 N,N-dimethylaminoisopropanol 1981 10 20 2000 12 27 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd without isomeric designation 3 *D011412 Propanolamines J Pharm Pharmacol 1981;33(8):549 MEG WXM WXM M0099734 N,N-dimethylaminoisopropanol C0067381 108-16-7 T109 Organic Chemical T131 Hazardous or Poisonous Substance 53636-15-0 ((R)-isomer) 53636-16-1 (tartrate[1:1](R)-(R-(R*,R*))-isomer) 53636-17-2 ((S)-isomer) 53636-18-3 (tartrate[1:1](S)-(R-(R*,R*))-isomer) 53657-16-2 ((+-)-isomer) M0099734 M0319403 M0099734 M0319404 M0099734 M0319400 M0099734 M0319402 M0099734 M0319401 T129738 N,N-dimethylaminoisopropanol T129735 DMAIP T129736 DMIPA T129737 N,N-dimethylisopropanolamine M0319403 N,N-dimethylaminoisopropanol tartrate (1:1), (S)-(R-(R*,R*))-isomer C0955238 53636-18-3 T109 Organic Chemical M0099734 M0319403 T349403 N,N-dimethylaminoisopropanol tartrate (1:1), (S)-(R-(R*,R*))-isomer 1999 08 18 M0319404 N,N-dimethylaminoisopropanol, (+-)-isomer C0955239 53657-16-2 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0099734 M0319404 T349404 N,N-dimethylaminoisopropanol, (+-)-isomer 1999 08 18 M0319400 N,N-dimethylaminoisopropanol, (R)-isomer C0955235 53636-15-0 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0099734 M0319400 T349400 N,N-dimethylaminoisopropanol, (R)-isomer 1999 08 18 M0319402 N,N-dimethylaminoisopropanol, (S)-isomer C0955237 53636-17-2 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0099734 M0319402 T349402 N,N-dimethylaminoisopropanol, (S)-isomer 1999 08 18 M0319401 N,N-dimethylaminoisopropanol tartrate (1:1), (R)-(R-(R*,R*))-isomer C0955236 53636-16-1 T109 Organic Chemical M0099734 M0319401 T349401 N,N-dimethylaminoisopropanol tartrate (1:1), (R)-(R-(R*,R*))-isomer 1999 08 18 C006377 (N)1-acetylisoniazid 1974 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 biologically inactive metabolite of isoniazid 39 *ISONIAZID (74-76) ACETIC ACIDS (74-76) D007538 Isoniazid *Q000031 analogs ; derivatives Annals Internal Med 84(2):181;1976 Can Med Assoc J 109(6):483;1973 NLM TWD TWD M0048887 (N)1-acetylisoniazid C0043643 1078-38-2 77280-85-4 (mono-HCl) M0048887 M0309540 T078890 (N)1-acetylisoniazid M0309540 (N)1-acetylisoniazid monohydrochloride C0951514 77280-85-4 M0048887 M0309540 T339540 (N)1-acetylisoniazid monohydrochloride 1999 08 18 C006367 3-beta-acetoxy-27-nor-5-cholesten-25-one 1974 01 01 1987 09 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 starting material for synthesizing 24,25-dihydroxy-vitamin D(3) 0 *CHOLESTENES (74-75) *STEROLS (74-87) NORSTEROIDS (74-82) *D002783 Cholestenones Biochemistry 12(24):4852;1973 NLM PEH NLM M0048874 3-beta-acetoxy-27-nor-5-cholesten-25-one C0602688 0 T078877 3-beta-acetoxy-27-nor-5-cholesten-25-one C076714 spe-4 protein 1992 10 15 2001 01 31 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; involved in sperm morphogenesis in the nematode, Caenorhabditis elegans 3 *D008565 Membrane Proteins J Cell Biol 1992 Oct;119(1):55-8 BXB WXM WXM M0206227 spe-4 protein C0172339 148710-61-6 T236232 spe-4 protein T236231 spe-4 gene product C076739 oncogene protein ryk 1992 10 15 2001 01 31 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source 2 *ONCOGENE PROTEINS, FUSION (92-95) *D015513 Oncogene Proteins D011505 Protein-Tyrosine Kinase J Virol 1992 Oct;66(10):5975-87 THA WXM WXM M0206292 oncogene protein ryk C0172396 148970-46-1 T236297 oncogene protein ryk T236296 v-ryk protein C006375 acetylgitoxin 1974 01 01 1982 06 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *DIGITALIS GLYCOSIDES (74-78) ACETIC ACIDS (74-78) D000112 Acetyldigitoxins *Q000031 analogs ; derivatives Biull Eksp Biol Med 75(10):61;1973 Europ J Clin Pharmacol 12:445;1977 Europ J Clin Pharmacol 13(5):389;1978 NLM CHA NLM M0048886 acetylgitoxin C0050518 7242-40-2 T078889 acetylgitoxin C076935 Tc 120 proteinase 1992 10 25 2001 01 31 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 found in cell-free extracts of Trypanosoma cruzi epimastigotes; 120 kDa protein; hydrolyzes N-Z-Gly-Gly-Arg-AMC as well as N-Z-Arg-AMC, N-Z-Phe-Arg-AMC ; N-glutaryl-Gly-Arg-AMC 1 *D003546 Cysteine Endopeptidases D015800 Protozoan Proteins Biochem Biophys Res Commun 1992 Sep 30;187(3):1466-73 RLS WXM WXM M0206765 Tc 120 proteinase C0654143 EC 3.4.22.- T236770 Tc 120 proteinase T236769 alkaline protease (T cruzi) C006386 jatrophone 1974 01 01 1994 02 03 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN refers to (2R-(2R*,3aR*,9E,12Z))-isomer; structure 8 *ANTINEOPLASTIC AGENTS (74-77) ETHERS, CYCLIC (74-82) PLANT EXTRACTS (74-77) *D004224 Diterpenes Biochim Biophys Acta 327(1):92;1973 J Am Chem Soc 98(8):2295;1976 NLM BMB NLM M0048912 jatrophone C0064140 2,3,7,8-tetrahydro-2,5,8,8,12-pentamethyl-3 alpha, 6-epoxy-3 alphaH-cyclopentacyclododecin-4,11-dione 29444-03-9 T078915 jatrophone C430887 signal recognition particle RNA 3'-adenylating enzyme 2001 07 17 2001 2002 GenBank AY029162 1 *D009713 Nucleotidyltransferases J Biol Chem 2001 Jun 15;276(24):21791-6 THA THA M0393554 signal recognition particle RNA 3'-adenylating enzyme C0967776 EC 2.7.7.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T454505 signal recognition particle RNA 3'-adenylating enzyme 2001 07 17 T454506 SRP RNA adenylating enzyme 2001 07 17 C006394 Acid Violet 6B 1974 01 01 1996 05 14 1996 1997 1998 1999 2000 2001 2002 structure 0 *DYES (74-79) *D001557 Benzenesulfonates IARC Mongr Erol Carcinog Risk Chem Man 16:153;1978 J Am Vet Med Assoc 164(6):623;1974 J Nat Cancer Inst 51(4):1337;1973 Toxicol 7(3):367;1977 NLM PML NLM M0048932 Acid Violet 6B C0050555 (4-(p-(dimethylamino)-alpha-(p-(ethyl(m-sulfobenzyl)amino)phenyl)benzylidene)-2,5-cyclohexadien-1-yl idene)ethyl(m-sulfobenzyl)ammonium hydroxide inner salt 1694-09-3 M0048932 M0048926 M0048932 M0048929 M0048932 M0048930 M0048932 M0048925 M0048932 M0048928 M0048932 M0048927 M0048932 M0048931 T078935 Acid Violet 6B M0048926 FD;C violet no. 1 C0117379 M0048932 M0048926 T078929 FD;C violet no. 1 M0048929 food violet No. 2 C0118101 M0048932 M0048929 T078932 food violet No. 2 M0048930 violet 6B C0148425 M0048932 M0048930 T078933 violet 6B M0048925 C.I. 42640 C0107813 M0048932 M0048925 T078928 C.I. 42640 M0048928 benzyl violet 4B C0105700 M0048932 M0048928 T078931 benzyl violet 4B M0048927 acid violet 49 C0101238 M0048932 M0048927 T078930 acid violet 49 M0048931 violet No. 1 C0148426 M0048932 M0048931 T078934 violet No. 1 C006396 acofriose 1975 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 3 *DEOXY SUGARS (75-82) MANNOSE/analogs D008358 Mannose *Q000031 analogs ; derivatives J Bact 120(2):672;1974 NLM VSR NLM M0048934 acofriose C0050566 6-deoxy-3-O-methylmannose 4598-54-3 T078937 acofriose C006398 21-acryloxyprogesterone 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PROGESTERONE (74-75) ACRYLATES (74-75) D011374 Progesterone *Q000031 analogs ; derivatives Gynec Investig 4(3):165;1973 NLM NLM M0048937 21-acryloxyprogesterone C0602701 27953-65-7 T078940 21-acryloxyprogesterone C061818 1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine 1989 12 27 2001 08 20 1998 1999 2000 2001 2001A 2002 RN ; structure given in first source 34 D013941 Thymine *Q000031 analogs ; derivatives D019434 HIV-1 Reverse Transcriptase Q000037 antagonists ; inhibitors J Med Chem 1989;32(12):2507 TPW TWD TWD M0171310 1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine C0044083 123027-56-5 D000998 Antiviral Agents D018894 Reverse Transcriptase Inhibitors D019380 Anti-HIV Agents T201315 1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine T201312 1-((2-hydroxyethoxy)methyl)-6-phenylthiothymine T201313 6-HEPT T201314 HMPTT C006404 actinoxanthine 1974 01 01 1993 05 03 1994 1995 1996 1997 1998 1999 2000 2001 2002 Russian drug 2 PEPTIDES (74-93) *D017561 Antibiotics, Peptide Dokl Akad Nauk SSSR 214(6):140;1973 J Antibiotics 29(10):1026;1976 NLM BXB TPW M0048949 actinoxanthine C0050664 59680-34-1 T078952 actinoxanthine UD 9:79P C006406 1-acylglycerophosphorylinositol 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *PHOSPHIDYLINOSITOLS (75-87) *PHOSPHOINOSITIDES (74-75) *D008246 Lysophospholipids J Biol Chem 248(20):7060;1973 NLM NLM M0048950 1-acylglycerophosphorylinositol C0044259 0 T078953 1-acylglycerophosphorylinositol C055019 1-diethylaminoethylphenobarbital 1988 03 31 2001 08 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source; RN given refers to parent compound 1 D010634 Phenobarbital *Q000031 analogs ; derivatives Arch Pharm (Weinheim) 1987;320(11):1103 TPW CCR CCR M0155094 1-diethylaminoethylphenobarbital C0632960 1164-33-6 110927-31-6 ((R)-isomer) 110947-87-0 ((S)-isomer) M0155094 M0323575 M0155094 M0323576 T185099 1-diethylaminoethylphenobarbital T185098 DEAE-phenobarbital M0323575 1-diethylaminoethylphenobarbital, (R)-isomer C0957530 110927-31-6 M0155094 M0323575 T353575 1-diethylaminoethylphenobarbital, (R)-isomer 1999 08 18 M0323576 1-diethylaminoethylphenobarbital, (S)-isomer C0957531 110947-87-0 M0155094 M0323576 T353576 1-diethylaminoethylphenobarbital, (S)-isomer 1999 08 18 C006412 adenylyl-(3'-5')-adenosine 1974 01 01 1988 08 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 17 *ADENINE NUCLEOTIDES (74-79) ADENOSINE MONOPHOSPHATE/*analogs (74-88) ADENOSINE/analogs (79-81) *D015226 Dinucleoside Phosphates Biochemistry 13(5):981;1974 Biochemistry 15(4):756;1976 Nucleic Acids Res 5(11):4417;1978 NLM RGM NLM M0048961 adenylyl-(3'-5')-adenosine C0050817 2391-46-0 T078964 adenylyl-(3'-5')-adenosine C006413 adenylyl-(3'-5')-uridine 1974 01 01 1988 08 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 4 *ADENINE NUCLEOTIDES (74-79) ADENOSINE MONOPHOSPHATE/*analogs (74-88) URIDINE (74-75) URIDINE/*analogs (75-81) *D015226 Dinucleoside Phosphates Biochemistry 13(5):981;1974 Biochemistry 16(15):3322;1977 Nature 253(5490):324;1975 NLM RGM NLM M0048962 adenylyl-(3'-5')-uridine C0050821 3051-84-1 T078965 adenylyl-(3'-5')-uridine C075326 1,4,5,8-naphthalene tetracarboxylic acid 4,5-anhydride 1992 07 27 2001 08 23 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source; RN refers to the monosodium salt, monohydrate 3 *D009281 Naphthalenes *D011753 Pyrones Acta Crystallogr C 1992 Mar 15;48(Pt 3):460-5 RLS TWD TWD M0203003 1,4,5,8-naphthalene tetracarboxylic acid 4,5-anhydride C0169637 141193-56-8 M0203003 M0203002 T233008 1,4,5,8-naphthalene tetracarboxylic acid 4,5-anhydride T233005 1,3-dioxo-1H,3H-naphtho(1,8-cd)pyran-6,7-dicarboxylate T233006 1,4,5,8-NTCAA M0203002 1,4,5,8-naphthalene tetracarboxylic acid 4,5-anhydride, monosodium salt, monohydrate C0210114 M0203003 M0203002 T233007 1,4,5,8-naphthalene tetracarboxylic acid 4,5-anhydride, monosodium salt, monohydrate C006427 afrodex 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination of above for treatment of male impotence 0 *D008777 Methyltestosterone *D013331 Strychnine *D015016 Yohimbine D004338 Drug Combinations Curr Therap Res 16(1):96;1974 NLM NLM M0048994 afrodex C0602720 Afrodex 8054-03-3 T078997 afrodex C006421 1,5-I-AEDANS 1974 01 01 2001 08 23 1997 1998 1999 2000 2001 2001A 2002 fluorescent probes which are sulfhydryl reagents; combine reactivity of iodoacetamide toward sulfhydryl groups with spectral properties of naphthalenesulfonic acids; structure 227 *ETHYLENEDIAMINES (76-79) IODINE (74-76) IODOACETAMIDE/*analogs (75-82) IODOACETAMIDE/analogs (76-80) *D009282 Naphthalenesulfonates D013439 Sulfhydryl Reagents Arch Biochem Biophys 175:279;1976 Biochem Biophys Res Commun 87(3):911;1979 Biochemistry 12(21):4154;1973 Biochemistry 17(11):2139;1978 Biochemistry 17(21):4419;1978 Biochemistry 1979;18(13):2759 Biochemistry 1980;19(4):774 Eur J Biochem 88(2):411-20;1978 Eur J Biochem 97(2):519;1979 FEBS Lett 1979;105(2):259 FEBS Lett 1980;109(2):216 J Biol Chem 254(15):7105;1979 Nucleic Acids Res 1979;7(6):1485 NLM TWD TWD M0048985 1,5-I-AEDANS CT010745 N-(iodoacetylaminoethyl)-5-naphthylamine-1-sulfonic acid 36930-63-9 D005456 Fluorescent Dyes T078988 1,5-I-AEDANS T078985 1,5-IAEDANS T078986 5-(2-iodoacetamidoethyl)aminonaphthalene-1-sulfonate T078987 N-iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine C006431 agnosterol 1974 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 lanosterol is the 8,24-diene; isomerizes the delta-8 ; is further dehydrated; structure 0 *LANOSTEROL (74-77) D007810 Lanosterol *Q000031 analogs ; derivatives J Chem Soc (Perkin I) 15:1583;1973 NLM VSR NLM M0049004 agnosterol C0602721 5 alpha-lanosta-7,9(11),24-trien-3 beta-ol 472-29-7 T079007 agnosterol C006433 akeson 1974 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 organ hydrolysate used in treatment of intervertebral disk pain 0 *D014020 Tissue Extracts Med Monats 27(8):372;1973 NLM VSR NLM M0049005 akeson C0602722 76359-34-7 T079008 akeson C006485 ambuphylline 1970 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *AMINO ALCOHOLS (70-82) *THEOPHYLLINE (70-75) D013806 Theophylline *Q000031 analogs ; derivatives NLM TWD TWD M0049079 ambuphylline C0602745 theophylline cpd with 2-amino-2-methyl-1-propanol 5634-34-4 T079082 ambuphylline T079081 theophylline aminoisobutanol C023050 spiro-3-oxiranylandrostan-17-ol 1980 01 01 2001 01 31 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 active-site-directed irreversible inhibitor of delta(5)-3-ketosteroid isomerase; RN refers to (3beta)-isomer 1 *D000732 Androstanols Biochem Biophys Res Commun 91(3):783;1979 NLM CCR CCR M0079821 spiro-3-oxiranylandrostan-17-ol C0075010 Spiro(androstane-3,2'-oxiran)-17-ol, (3beta,5alpha,17beta)- 2066-43-5 T109824 spiro-3-oxiranylandrostan-17-ol T109822 spiro(5 alpha-androstane-3,2'-oxiran)-17 beta-ol T109823 spiro-3-oxiranyl-5 alpha-androstan-17 beta-ol C006443 albutoin 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D013867 Thiohydantoins NLM NLM M0049027 albutoin C0051108 3-allyl-5-isobutyl-2-thiohydantoin 830-89-7 T079030 albutoin C006511 aminocarb 1975 01 01 2000 10 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 structure 32 TOLUIDINES (75-81) *D002219 Carbamates J Ag Food Chem 24(1):13;1976 NLM CCR CCR M0049121 aminocarb C0051627 2032-59-9 T109 Organic Chemical T131 Hazardous or Poisonous Substance D007308 Insecticides, Carbamate M0049121 M0049120 T079124 aminocarb T079122 4-dimethylamino-3-tolyl-N-methylcarbamate M0049120 Matacil C0127059 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0049121 M0049120 T079123 Matacil C006446 aldophosphamide 1975 01 01 1982 11 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 metabolite of cyclophosphamide; structure 30 *NITROGEN MUSTARD COMPOUNDS (75-79) ORGANOPHOSPHORUS COMPOUNDS (75-79) *D010752 Phosphoramide Mustards Cancer Res 1980;40(1):174 Cancer Res 34(11):2933;1974 Cancer Res 37(8):2538;1977 Cancer Treatment Rep 60(4):317;1976 NLM VSR NLM M0049031 aldophosphamide C0051130 35144-64-0 T079034 aldophosphamide C072235 michellamine A 1992 02 14 2001 08 23 1998 1999 2000 2001 2001A 2002 atropisomeric naphthylisoquinoline anti-HIV cytopathic alkaloid dimers; from tropical plant Ancistrocladus abbreviatus; structure given in first source 10 *D007546 Isoquinolines *D009281 Naphthalenes D013237 Stereoisomerism J Med Chem 1991;34(12):3402 BXB CCR CCR M0195771 michellamine A C0128430 137793-81-8 137893-48-2 (michellamine B) M0195771 M0325507 M0195771 M0195770 T225776 michellamine A M0325507 michellamine B C0128431 137893-48-2 M0195771 M0325507 T225774 michellamine B M0195770 michellamine C C0246686 M0195771 M0195770 T225775 michellamine C C006459 alophen 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D000880 Anthraquinones *D010635 Phenolphthaleins D004338 Drug Combinations Curr Therap Res 16(8):817;1974 NLM NLM M0049045 alophen C0591068 Aloin, mixt. with 3,3-bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone 76741-91-8 T079048 alophen C026421 17-methyl-17a-chloro-D-homoandrostan-3-ol 1980 10 06 2001 01 31 1998 1999 2000 2001 2001A 2002 RN given refers to (D)-isomer; structure in first source 1 *D000732 Androstanols Steroids 1980 Jul;36(1):87-96 RLS CCR CCR M0086783 17-methyl-17a-chloro-D-homoandrostan-3-ol C0611109 D-Homoandrostan-3-ol, 17a-chloro-17-methyl-, (3alpha,5beta,17alpha,17abeta)- 76571-91-0 T116786 17-methyl-17a-chloro-D-homoandrostan-3-ol T116784 17 alpha-methyl-17a beta-chloro-D-homo-5 beta-androstan-3 alpha-ol T116785 17-MCHAO C006466 1-allyl-2-benzyl-piperidine 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D010880 Piperidines Arch Int Pharmacodyn 203(2):268;1973 NLM NLM M0049053 1-allyl-2-benzyl-piperidine C0602742 29194-07-8 T079056 1-allyl-2-benzyl-piperidine C414097 nothapodytine B 2000 10 06 2000 2001 2002 isolated from Nothapodytes foetida; structure in first source 2 *D007212 Indolizines *D011804 Quinolines J Org Chem 2000 Aug 25;65(17):5212-5 THA THA M0370853 nothapodytine B C0961143 55854-89-2 T109 Organic Chemical T121 Pharmacologic Substance T426112 nothapodytine B 2000 10 06 T426113 mappicine ketone 2000 10 06 C006478 alpinigenine 1974 01 01 1980 11 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 alkaloid isolated form Papaver bracteatum; structure 0 BENZAZEPINES (74-81) BENZOPYRANS (74-79) *D000470 Alkaloids Acta Biol Med Germ 35(7):1019;1976 J Pharm Sci 62(10):1718;1973 NLM BGS NLM M0049069 alpinigenine C0051485 14028-91-2 T079072 alpinigenine C036418 3-acetoxy-7,15-oxido-16-oxaandrostan-17-one 1982 12 20 2001 01 31 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 *D000732 Androstanols *D013260 Steroids, Heterocyclic Steroids 1982 May;39(5):531-6 VSR CCR CCR M0110960 3-acetoxy-7,15-oxido-16-oxaandrostan-17-one C0617501 16-Oxaandrostan-17-one, 3-(acetyloxy)-7,15-epoxy-, (3alpha,5beta,7alpha,14beta,15alpha)- 84783-21-1 T140964 3-acetoxy-7,15-oxido-16-oxaandrostan-17-one T140962 3 alpha-acetoxy-7 alpha,15 alpha-oxido-16-oxa-5 beta,14 beta-androstan-17-one T140963 3-AOOA C006487 amicetose 1974 01 01 1980 11 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 DEOXY SUGARS (74-81) *D006601 Hexoses J Chem Soc 13(0):1400;1973 NLM NBM NLM M0049081 amicetose C0602746 2,3,6-trideoxy-D-erythro-hexose 27518-97-4 T079084 amicetose C006493 amidithion 1974 01 01 1980 11 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 CARBAMATES (74-81) *D009946 Organothiophosphorus Compounds J Agr Food Chem 25(3):583;1977 NLM NBM NLM M0049090 amidithion C0051590 O-O-dimethyl-S-(2-methoxyethylcarbamoylmethyl) dithiophosphate 919-76-6 T079093 amidithion C006497 1-aminoadenosine 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 D000241 Adenosine *Q000031 analogs ; derivatives Chem Pharm Bull 22(8):1938;1974 NLM NLM M0049092 1-aminoadenosine C0602749 5746-27-0 T079095 1-aminoadenosine C414099 17-isolevuglandin E4 2000 10 06 2000 2001 2002 structure in first source 1 *D011458 Prostaglandins E J Org Chem 2000 Aug 25;65(17):5315-26 THA THA M0370857 17-isolevuglandin E4 C0961147 0 T111 Eicosanoid T426118 17-isolevuglandin E4 2000 10 06 T426121 17-isoLGE(4) 2000 10 06 T426119 17-isolevuglandin E(4) 2000 10 06 T426120 10-acetyl-11-formyl-14-hydoxynonadeca-4,7,12,16-tetraenoic acid 2000 10 06 T426122 17-isoLGE4 2000 10 06 C414100 2,4-diphenylbutanoic acid 2000 10 06 2000 2001 2002 structure in first source 1 *D010654 Phenylbutyrates J Org Chem 2000 Aug 25;65(17):5371-81 THA THA M0370858 2,4-diphenylbutanoic acid C0961148 0 T109 Organic Chemical T426123 2,4-diphenylbutanoic acid 2000 10 06 T426124 2,4-diphenylbutyric acid 2000 10 06 C006508 N-(4-aminobutyl)methamphetamine 1974 01 01 1980 11 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 *METHAMPHETAMINE (74-75) BUTYLAMINES (74-81) D008694 Methamphetamine *Q000031 analogs ; derivatives FEBS Lett 36(3):339;1973 NLM NBM NLM M0049112 N-(4-aminobutyl)methamphetamine C0602759 1,4-Butanediamine, N-methyl-N-(1-methyl-2-phenylethyl)-, (S)- 78232-38-9 T079115 N-(4-aminobutyl)methamphetamine C006516 5-amino-4-chloro-(2,3-dihydroxy-1-phenyl)-3(2H)-pyridazinone 1974 01 01 1980 10 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 metabolite of herbicide, pyrazon; structure 0 CATECHOL (74-81) *D011724 Pyridazines Biochem Biophys Res Comm 54(2):760;1973 NLM NBM NLM M0049127 5-amino-4-chloro-(2,3-dihydroxy-1-phenyl)-3(2H)-pyridazinone C0602761 50512-54-4 T079130 5-amino-4-chloro-(2,3-dihydroxy-1-phenyl)-3(2H)-pyridazinone C006517 22-aminocholesterol 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 3 *CHOLESTEROL (74-75) AMINES (74-75) D002784 Cholesterol *Q000031 analogs ; derivatives J Org Chem 39(8):1065;1974 NLM NLM M0049128 22-aminocholesterol C0046652 50921-65-8 T079131 22-aminocholesterol C006521 2'-amino-2'-deoxy-5-fluorouridine 1974 01 01 1992 06 22 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *FLUORODEOXYURIDINE (74-75) D005467 Floxuridine *Q000031 analogs ; derivatives J Med Chem 17(4):466;1974 NLM MLH TPW M0049132 2'-amino-2'-deoxy-5-fluorouridine C0602764 51989-23-2 T079135 2'-amino-2'-deoxy-5-fluorouridine C006522 6'-amino-6'-deoxygentamicin A 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D005839 Gentamicins J Med Chem 17(9):1030;1974 NLM NLM M0049133 6'-amino-6'-deoxygentamicin A C0602765 53607-78-6 T079136 6'-amino-6'-deoxygentamicin A C006524 3 beta-amino-3-desoxydigoxigenin 1974 01 01 1980 10 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CARDANOLIDES (74-77) D004076 Digoxigenin *Q000031 analogs ; derivatives Helv Chim Acta 56(1):2782;1973 NLM NBM NLM M0049137 3 beta-amino-3-desoxydigoxigenin C0602766 3 beta-amino-12 beta,14-dihydroxy-5 beta,14 beta-card-20(22)-enolide 0 T079140 3 beta-amino-3-desoxydigoxigenin C006525 3 beta-amino-3-desoxygitoxigenin 1974 01 01 1980 10 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CARDANOLIDES (74-77) D004076 Digoxigenin *Q000031 analogs ; derivatives Helv Chim Acta 56(1):2782;1973 NLM NBM NLM M0049138 3 beta-amino-3-desoxygitoxigenin C0602767 3 beta-amino-14,16 beta-dihydroxy-5 beta,14 beta-card-20(22)-enolide 0 T079141 3 beta-amino-3-desoxygitoxigenin C006526 3 alpha-amino-3-desoxyoleandrigenin 1974 01 01 1977 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CARDANOLIDES (74-77) D004076 Digoxigenin *Q000031 analogs ; derivatives Helv Chim Acta 56(1):2782;1973 NLM NLM M0049139 3 alpha-amino-3-desoxyoleandrigenin C0602768 3 alpha-amino-14-hydroxy-16 beta-acetoxy-5 beta,14 beta-card-20(22)-enolide 0 T079142 3 alpha-amino-3-desoxyoleandrigenin C006527 3 beta-amino-3-desoxyuzarigenin 1974 01 01 1980 10 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CARDANOLIDES (74-77) D004076 Digoxigenin *Q000031 analogs ; derivatives Helv Chim Acta 56(1):2782;1973 NLM NBM NLM M0049140 3 beta-amino-3-desoxyuzarigenin C0602769 3 beta-amino-14-hydroxy-5 alpha,14 beta-card-20(22)-enolide 0 T079143 3 beta-amino-3-desoxyuzarigenin C006528 6-amino-4,10-diazachrysene 1974 01 01 1980 10 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PHENANTHRIDINES (74-76) AZA COMPOUNDS (74-81) *D002911 Chrysenes Farmaco(Sci) 29(6):449;1974 NLM NBM NLM M0049141 6-amino-4,10-diazachrysene C0602770 24902-11-2 T079144 6-amino-4,10-diazachrysene C006530 2-amino-4,7-dimethoxy-5-methylindan 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 rigid analog of DOM; structure 0 *D007189 Indans J Med Chem 17(2):161;1974 NLM NLM M0049142 2-amino-4,7-dimethoxy-5-methylindan C0602771 52904-71-9 T079145 2-amino-4,7-dimethoxy-5-methylindan C006531 2-amino-5,8-dimethoxy-6-methyl-1,2,3,4-tetrahydronaphthalene 1974 01 01 1978 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 rigid analog of DOM; structure 0 *NAPHTHALENES (74-78) *D013764 Tetrahydronaphthalenes J Med Chem 17(2):161;1974 NLM NLM M0049143 2-amino-5,8-dimethoxy-6-methyl-1,2,3,4-tetrahydronaphthalene C0602772 53609-01-1 T079146 2-amino-5,8-dimethoxy-6-methyl-1,2,3,4-tetrahydronaphthalene C074015 1,4,5,8-naphthalenetetracarboxylic acid 1992 05 08 2001 08 23 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 2 *D009281 Naphthalenes Acta Crystallogr C 1991 Nov 15;47(Pt 11):2315-9 THA TWD TWD M0199926 1,4,5,8-naphthalenetetracarboxylic acid C0167084 128-97-2 M0199926 M0199924 M0199926 M0199925 T229931 1,4,5,8-naphthalenetetracarboxylic acid T229928 1,4,5,8-naptetraCOOH M0199924 dicalcium 1,4,5,8-naphathalenetetracarboxylate pentahydrate C0246767 M0199926 M0199924 T229929 dicalcium 1,4,5,8-naphathalenetetracarboxylate pentahydrate M0199925 tetrasodium 1,4,5,8-naphthalenetetracarboxylate octahydrate C0167083 M0199926 M0199925 T229930 tetrasodium 1,4,5,8-naphthalenetetracarboxylate octahydrate C006533 O-(2-aminoethyl)phosphono-L-serine 1975 01 01 1980 03 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PHOSPHOLIPIDS (75-80) *SERINE/*analogs (75-80) D010768 Phosphoserine *Q000031 analogs ; derivatives Can J Biochem 52(8):718;1974 NLM RLS NLM M0049145 O-(2-aminoethyl)phosphono-L-serine C0602773 L-Serine, hydrogen (2-aminoethyl)phosphonate (ester) 53933-04-3 T079148 O-(2-aminoethyl)phosphono-L-serine C006534 4-(beta-aminoethyl)pyrazole 1974 01 01 1983 08 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 histamine analog; can induce cross-tolerance to histamine; RN given refers to di-HCl; RN for parent cpd not in Chemline 8/11/83; structure 0 ETHYLAMINES (74-78) *D011720 Pyrazoles Res Commun Chem Path Pharmacol 3(2):265;1972 NLM JSL NLM M0049146 4-(beta-aminoethyl)pyrazole C0602774 6429-11-4 T079149 4-(beta-aminoethyl)pyrazole C024228 tetraphenylarsonium oxotechnetiumbis(ethanedithiolate) 1980 05 14 2001 10 05 2001 2001A 2002 RN ; N1 from CA Vol 90 Form Index; RN in Chemline for (SP-5-21)-isomer, (99)Tc-labeled cpd: 69216-12-2 1 *ORGANOMETALLIC COMPOUNDS (80-89) *D001152 Arsenicals *D015609 Organotechnetium Compounds J Nucl Med 1980;21(3):279 MEG CCR CCR M0082209 tetraphenylarsonium oxotechnetiumbis(ethanedithiolate) C0609947 tetraphenylarsonium, bis(1,2-ethanedithiolato(2-)-S,S')oxotechnetate(1-) 70177-06-9 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T112212 tetraphenylarsonium oxotechnetiumbis(ethanedithiolate) C006539 1-N-(s)-4-amino-2-hydroxybutyryl-3'4'-deoxyneamine 1974 01 01 1982 09 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *NEOMYCIN (74-75) AMINOBUTYRIC ACIDS (74-75) GABA/analogs (74-82) D009355 Neomycin *Q000031 analogs ; derivatives J Antibiotics 26(5):304;1973 NLM VSR NLM M0049152 1-N-(s)-4-amino-2-hydroxybutyryl-3'4'-deoxyneamine C0602775 Streptamine, N1-(4-amino-2-hydroxy-1-oxobutyl)-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl)-, (S)- 42859-94-9 T079155 1-N-(s)-4-amino-2-hydroxybutyryl-3'4'-deoxyneamine C006540 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphate 1975 01 01 1982 12 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 substrate for enzyme dihydropteroate synthetase from Neisseria gonorrhoeae ; N. meningitidis; structure 1 *D011621 Pteridines J Pharm Sci 63(9):1474;1974 NLM VSR NLM M0049153 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphate C0045837 6863-06-5 T079156 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphate C006543 2-amino-4-hydroxy-6-(1',2',3'-trihydroxybutyl)-5,6,7,8- tetrahydropteridine 1974 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ALCOHOLS, BUTYL (74-82) *D011621 Pteridines J Nucl Biol Med 17(1):38;1973 NLM VSR NLM M0049155 2-amino-4-hydroxy-6-(1',2',3'-trihydroxybutyl)-5,6,7,8- tetrahydropteridine C0602776 51131-68-1 T079158 2-amino-4-hydroxy-6-(1',2',3'-trihydroxybutyl)-5,6,7,8- tetrahydropteridine C006544 5(4)-amino-4(5)-imidazolecarboxamide ureidosuccinate 1975 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *IMIDAZOLES (75-78) AMIDES (75-78) SUCCINATES (75-81) D000620 Aminoimidazole Carboxamide *Q000031 analogs ; derivatives Clin Ter 83(3):243;1977 Minerva Gastroenterol 18(4):245;1974 NLM RLS NLM M0049156 5(4)-amino-4(5)-imidazolecarboxamide ureidosuccinate C0048846 L-Aspartic acid, N-(aminocarbonyl)-, compd. with 5-amino-1H-imidazole-4-carboxamide (1:1) 34879-34-0 T079159 5(4)-amino-4(5)-imidazolecarboxamide ureidosuccinate C006546 2-amino-4'-isopropyldiphenyl sulfide 1974 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 SULFIDES (74-82) *D000814 Aniline Compounds Acta Polon Pharm 30(6):561;1973 NLM VSR NLM M0049158 2-amino-4'-isopropyldiphenyl sulfide C0602777 Benzenamine, 2-((4-(1-methylethyl)phenyl)thio)- 52167-40-5 T079161 2-amino-4'-isopropyldiphenyl sulfide C006548 aminokrovin 1974 01 01 1982 09 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 product of acid hydrolysis of human blood 2 *D010952 Plasma Substitutes Kardiologiia 18(3):76;1978 Probl Gematol Pereliv Krovi 18(2):8;1973 Probl Gematol Pereliv Krovi 22(12):16;1977 NLM VSR NLM M0049160 aminokrovin C0051645 76773-71-2 T079163 aminokrovin Russ Drug Index 2nd ed. p. 88 C436299 benzoatotris(6-methyl-2-pyridylmethyl)amineiron(II) 2001 10 05 2001 10 06 2001 2001A 2002 1 *D005296 Ferrous Compounds J Biol Inorg Chem 2001 Mar;6(3):275-84 THA THA THA M0400865 benzoatotris(6-methyl-2-pyridylmethyl)amineiron(II) 0 T109 Organic Chemical T464949 benzoatotris(6-methyl-2-pyridylmethyl)amineiron(II) 2001 10 05 T464950 (Fe(6-Me3-TPA)(O2CPh)) 2001 10 05 C006554 4-amino-1-phenylpyrazolone 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 demethylated product of aminopyrine metabolism 0 *D011720 Pyrazoles Eur J Biochem 38(1):73;1973 NLM NLM M0049169 4-amino-1-phenylpyrazolone C0602781 0 T079172 4-amino-1-phenylpyrazolone C078030 UL21 protein, Pseudorabies virus 1992 12 11 2001 02 01 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 homolog of the herpes simplex virus UL21 gene product; capsid protein involved in capsid maturation; amino acid sequence has been determined 3 *D002213 Capsid J Virol 1992 Dec;66(12):7096-7103 RLS WXM WXM M0209294 UL21 protein, Pseudorabies virus C0379732 0 M0209294 M0209293 T239299 UL21 protein, Pseudorabies virus M0209293 UL21 gene product C0379731 M0209294 M0209293 T239298 UL21 gene product C006555 N-2-aminophenyl-N'-thiourea 1974 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 AMINES (74-75) *D010670 Phenylthiourea Pharmazie 28(10):682;1973 NLM TWD TWD M0049171 N-2-aminophenyl-N'-thiourea C0602783 Thiourea, N-(2-aminophenyl)-N'-phenyl- 21578-46-1 T079174 N-2-aminophenyl-N'-thiourea T079173 N-o-aminophenyl-N'-thiourea C078031 phosphoprotein pp31, Baculovirus 1992 12 11 2001 02 01 1997 1998 1999 2000 2001 2001A 2002 MW 31 kDa; associated with virogenic stroma; amino acid sequence has been determined 4 *D004268 DNA-Binding Proteins *D010750 Phosphoproteins D017924 Nucleopolyhedrovirus J Virol 1992 Dec;66(12):7113-20 RLS WXM WXM M0209296 phosphoprotein pp31, Baculovirus C0655422 0 T239301 phosphoprotein pp31, Baculovirus T239300 pp31, Baculovirus C006565 amiphos 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ACETAMIDES (74-75) *D009946 Organothiophosphorus Compounds Gig Sanit 7:34;1974 Veterinariia 8:101;1976 Vopr Pitan 32(4):71;1973 NLM NLM M0049186 amiphos C0051685 O,O-dimethyl-S-2-(acetylamino)ethyl dithiophosphate 13265-60-6 T079189 amiphos C032020 16-bromoepiandrosterone 1981 10 28 2001 02 01 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 DHEA analog that is 60x as potent as DHEA against G6PDH 5 D000738 Androsterone *Q000031 analogs ; derivatives Carcinogenesis 1981;2(7):683 NBM CCR CCR M0100201 16-bromoepiandrosterone C0044914 28507-02-0 M0100201 M0100199 T130205 16-bromoepiandrosterone T130204 16-Br-epi M0100199 16 alpha-bromoepiandrosterone C0090523 M0100201 M0100199 T130203 16 alpha-bromoepiandrosterone C078099 easter proteinase 1992 12 14 2001 02 01 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence of light chain from Drosophila given in first source; has high homology with light chain of Tachypleus proclotting enzyme 9 *D012697 Serine Endopeptidases Biochim Biophys Acta 1992 OCT 20;1132(3):290-6 BVL WXM WXM M0209439 easter proteinase C0175100 EC 3.4.21.- T239444 easter proteinase T239443 easter gene product C006573 1,4-androstadiene-3,17-dione 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 21 *ANDROSTENES (74-76) 17-KETOSTEROIDS (74-76) KETOSTEROIDS (74-76) *D000730 Androstadienes Chem Pharm Bull 23(10):2358;1975 Planta Med 30(4):360;1976 Steroids 22(2):293;1973 NLM NLM M0049191 1,4-androstadiene-3,17-dione C0043982 897-06-3 T079194 1,4-androstadiene-3,17-dione C006574 androsta-3,5-diene-7,17-dione 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ANDROSTENES (74-75) 17-KETOSTEROIDS (74-75) KETOSTEROIDS (74-75) *D000730 Androstadienes Endocrinol Exp 5(1):205;1971 NLM NLM M0049192 androsta-3,5-diene-7,17-dione C0602787 1420-49-1 T079195 androsta-3,5-diene-7,17-dione C436378 oxo(N,N-bis(2-thioethyl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)propylamine)(phenylthio)technetium 2001 10 06 2001 2002 a 5-HT(1A) receptor imaging agent; structure in first source 0 *D015609 Organotechnetium Compounds J Biol Inorg Chem 2001 Mar;6(3):256-65 THA THA M0400956 oxo(N,N-bis(2-thioethyl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)propylamine)(phenylthio)technetium 0 T109 Organic Chemical T121 Pharmacologic Substance T465087 oxo(N,N-bis(2-thioethyl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)propylamine)(phenylthio)technetium 2001 10 06 T465088 99m-Tc yuckyB 2001 10 06 C006583 (8S,9S)-8,9-anhydroerythromycin-B 6,9-hemiacetal-8,9-epoxide 1974 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ERYTHROMYCIN (74-75) D004917 Erythromycin *Q000031 analogs ; derivatives Helv Chim Acta 56(5):1557;1973 NLM VSR NLM M0049204 (8S,9S)-8,9-anhydroerythromycin-B 6,9-hemiacetal-8,9-epoxide C0602789 Erythromycin, 9-deoxo-6,12-dideoxy-6,9:8,9-diepoxy-, (8S,9S)- 43179-91-5 T079207 (8S,9S)-8,9-anhydroerythromycin-B 6,9-hemiacetal-8,9-epoxide C006585 2,5-anhydro-D-glucitol-6-phosphate 1974 01 01 1980 11 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 SORBITAL/analogs (75-81) SORBITOL (74-75) *D006600 Hexosephosphates J Biol Chem 248(23):8174;1973 NLM RLS NLM M0049208 2,5-anhydro-D-glucitol-6-phosphate C0602790 0 T079211 2,5-anhydro-D-glucitol-6-phosphate C078135 HC toxin reductase 1992 12 16 2001 02 01 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 NADPH-dependent enzyme from maize which inactivates the cyclic tetrapeptide, HC toxin, from Cochliobolus carbonum; amino acid sequence given in first source 3 *D010088 Oxidoreductases Science 1992 Nov 6;258(5084):985-7 BVL WXM WXM M0209521 HC toxin reductase C0527412 EC 1.- T239526 HC toxin reductase T239525 HM1 gene product C006594 anthraxin 1974 01 01 1985 09 23 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 used diagnostically as agent in skin tests for anthrax 3 *D000942 Antigens, Bacterial D000485 Allergens J Hyg Epidemio Microbiol Immunol (Praha) 17(3):279;1973 NLM RLS NLM M0049221 anthraxin C0206845 0 T079224 anthraxin C436379 oxo(N,N-bis(2-thioethyl)-3--(4-(2-methoxyphenyl)piperazin-1-yl)propylamine)(phenylethylthio)technetium 2001 10 06 2001 2002 a 5-HT(1A) receptor imaging agent; structure in first source 0 *D015609 Organotechnetium Compounds J Biol Inorg Chem 2001 Mar;6(3):256-65 THA THA M0400957 oxo(N,N-bis(2-thioethyl)-3--(4-(2-methoxyphenyl)piperazin-1-yl)propylamine)(phenylethylthio)technetium 0 T109 Organic Chemical T121 Pharmacologic Substance T465089 oxo(N,N-bis(2-thioethyl)-3--(4-(2-methoxyphenyl)piperazin-1-yl)propylamine)(phenylethylthio)technetium 2001 10 06 T465090 99m-Tc yuckyA 2001 10 06 C006603 antistaphylolysin 1974 01 01 1997 10 09 1997 1998 1999 2000 2001 2002 18 *HEMOLYSINS (74-97) STAPHYLOCOCCUS (74-81) *D007136 Immunoglobulins D000907 Antibodies, Bacterial Nouv Presse Med 7(33):2966;1978 Z Haut GeschlKr 48(12):487;1973 NLM PML NLM M0049229 antistaphylolysin C0052097 0 T079232 antistaphylolysin C006604 antistreptopolysaccharide 1974 01 01 1987 04 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *D000907 Antibodies, Bacterial *D011135 Polysaccharides, Bacterial D013297 Streptococcus pyogenes D013291 Streptococcus Q000276 immunology Singapore Med J 14(3):452;1973 NLM MEG NLM M0049230 antistreptopolysaccharide C0052101 0 T079233 antistreptopolysaccharide C006610 aplysiatoxin 1974 01 01 1984 08 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 52 *LACTONES (74-84) *MARINE TOXINS (74-78) *D008235 Lyngbya Toxins J Am Chem Soc 96(7):2245;1974 J Nat Products 38(1):1;1975 NLM GTC NLM M0049235 aplysiatoxin C0052161 52659-57-1 T079238 aplysiatoxin C006611 alpha-apo-8-carotenol 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ALCOHOLS (74-75) *D002338 Carotenoids Helv Chim Acta 56(3):1124;1973 NLM NLM M0049236 alpha-apo-8-carotenol C0602799 8'-Apo-epsilon,psi-carotenol, (6R)- 43126-13-2 T079239 alpha-apo-8-carotenol C006623 arbusculin B 1974 01 01 1982 12 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 allergenic; structure 0 LACTONES (74-81) *D012717 Sesquiterpenes D000485 Allergens J Org Chem 39(2):186;1974 NLM VSR NLM M0049251 arbusculin B C0602802 24164-19-0 T079254 arbusculin B C006625 arenomycin B 1974 01 01 1990 02 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 polyene antibiotic; structure 0 D011090 Polyenes Antibiotiki 18(10):872;1973 NLM PAS NLM M0049255 arenomycin B C0602803 51449-09-3 T079258 arenomycin B C006635 arugosin C 1974 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 phenolic metabolite of mutant strain of Aspergillus Rugulosus; structure 0 BENZOPYRANS (74-82) *D001584 Benzoxepins J Chem Soc (Perkin I) 17:1825;1973 NLM VSR NLM M0049268 arugosin C C0602806 1,12a-dihydro-6,8-dihydroxy-1-(1-hydroxy-1-methylethyl)-4-methyl-9-(3-methylbut-2-enyl)(1)benzopy rano(4,5-bc)(1)benzoxepin-7(2H)-one 50875-10-0 T079271 arugosin C C436294 AtMEKK1 protein 2001 10 05 2002 01 17 2001 2001A 2001B 2002 isolated from Arabidopsis thaliana; amino acid sequence in first source 1 *D017346 Protein-Serine-Threonine Kinases Biochem Biophys Res Commun 1998 Dec 18;253(2):532-43 THA NLM THA M0400858 AtMEKK1 protein EC 2.7.1.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T464938 AtMEKK1 protein 2001 10 05 T464939 AtMEKK1 gene product 2001 10 05 C037918 CP 59430 1983 05 16 2000 07 31 2001 2002 azide analog of prazosin; structure given in first source 1 *D001386 Azides *D011799 Quinazolines Proc Natl Acad Sci USA 1983;80(8):2102 MEG CCR sjn M0114429 CP 59430 C0618543 Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(4-azidobenzoyl)- 86329-06-8 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0114429 M0114426 T144433 CP 59430 T144431 CP-59,430 T144432 CP-59430 M0114426 2-(4-(4-azidobenzoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline C0618540 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid M0114429 M0114426 T144430 2-(4-(4-azidobenzoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline C006639 ascofuranol 1974 01 01 1983 08 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D012717 Sesquiterpenes J Antibiotics 26(11):676;1973 NLM ACS NLM M0049271 ascofuranol C0602809 51759-79-6 T079274 ascofuranol C006641 ascorbyl monolaurate 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 D001205 Ascorbic Acid *Q000031 analogs ; derivatives J Pharm Soc Jap 94(8):917;1974 NLM NLM M0049273 ascorbyl monolaurate C0602810 6-0-lauryl-1-ascorbic acid 16690-40-7 T079276 ascorbyl monolaurate C006689 bencain 1975 01 01 2000 12 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 BENZOATES (75-81) *D001565 Benzoates Bull Exp Bio Med (Mosk) Eng Trans 76(12):1425;1974 NLM TWD TWD M0049355 bencain C0602820 2-diethylaminoethylbenzoate 2618-38-4 T109 Organic Chemical T121 Pharmacologic Substance T079358 bencain Negwer 1996 C006645 1-0-(L-beta-aspartyl)-beta-D-glucopyranose 1974 01 01 1982 09 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ASPARTIC ACID (74-75) *GLYCOSIDES (74-75) GLUCOSIDES (74-82) D001224 Aspartic Acid *Q000031 analogs ; derivatives Carbohyd Res 29(1):25;1973 NLM VSR NLM M0049279 1-0-(L-beta-aspartyl)-beta-D-glucopyranose C0602811 L-Aspartic acid, 4-beta-D-glucopyranosyl ester 42721-22-2 T079282 1-0-(L-beta-aspartyl)-beta-D-glucopyranose C059644 B-DOMP protocol 1989 06 20 2000 11 30 2001 2002 chemotherapy protocol consisting of above compounds ; N(4)-behenoyl-1-cytarabine; used in treatment of acute non-lymphocytic leukemia 3 *D000971 Antineoplastic Combined Chemotherapy Protocols D003561 Cytarabine Q000031 analogs ; derivatives D003630 Daunorubicin D011239 Prednisolone D014750 Vincristine D015122 6-Mercaptopurine Nippon Ketsueki Gakkai Zasshi 1988;51(8):1641 RLS TWD sjn M0165869 B-DOMP protocol C0052852 0 T061 Therapeutic or Preventive Procedure T195874 B-DOMP protocol C006652 austadiol 1974 01 01 1982 06 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 main toxic metabolite of Aspergillus ustus; structure 0 ALDEHYDES (74-76) *D001578 Benzopyrans D009183 Mycotoxins J Chem Soc (Perkin I) 1(0):45;1974 J Chem Soc (Perkin I) 2:204;1976 NLM CHA NLM M0049298 austadiol C0052682 (7R,8S)-7,8-dihydro-7,8-dihydroxy-3,7-dimethyl-6-oxo- 6H-2-benzopyran-5-carbaldehyde 53043-28-0 T079301 austadiol C006665 4-azobenzoate 1974 01 01 2001 02 06 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 BENZOATES (74-81) *D001391 Azo Compounds Immunochemistry 10(8):495;1973 J Exptl Med 146(1):74;1977 J Exptl Med 146(1):91;1977 NLM CCR CCR M0049320 4-azobenzoate C0048102 586-91-4 T079323 4-azobenzoate T079321 p-azobenzoate T079322 para-azobenzoate C011275 3-hydroxybenzaldehyde 1976 01 01 2001 02 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 *D001547 Benzaldehydes Europ J Biochem 58:467;1975 NLM CCR CCR M0057447 3-hydroxybenzaldehyde C0525176 100-83-4 T087450 3-hydroxybenzaldehyde T087448 m-hydroxybenzaldehyde T087449 meta-hydroxybenzaldehyde C029668 enkephalin-Met, des-Tyr(1)- 1981 06 10 2000 12 19 1998 1999 2000 2001 2001A 2002 causes retrograde amnesia in rats; RN given refers to (L-Met-L-Phe)-isomer 8 *ENKEPHALINS (81-82) D004744 Enkephalin, Methionine *Q000031 analogs ; derivatives Neurosci Lett 1981;22(2):189 RLS WXM WXM M0094492 enkephalin-Met, des-Tyr(1)- C0059342 61370-88-5 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance 68800-28-2 (mono-HCl(L-Met-L-Phe)-isomer) M0094492 M0318452 T124495 enkephalin-Met, des-Tyr(1)- T124490 (Des-Tyr)Met-Enk T124491 1-de-Tyr-Met-enkephalin T124493 enkephalin-Met, destyrosine(1)- T124492 Met-enkephalin, des-Tyr(1) T124494 methionine-enkephalin, des-Tyr(1)- M0318452 enkephalin-Met, des-Tyr(1)- monohydrochloride, (L-Met-L-Phe)-isomer C0954827 68800-28-2 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance M0094492 M0318452 T348452 enkephalin-Met, des-Tyr(1)- monohydrochloride, (L-Met-L-Phe)-isomer 1999 08 18 C006658 azidocodeine 1974 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *MORPHINANS (74-75) AZIDES (74-79) D003061 Codeine *Q000031 analogs ; derivatives J Pharm Pharmacol 25(12):929;1973 NLM NLM M0049308 azidocodeine C0602812 6-deoxy-6-azidodihydroisocodeine 22958-08-3 T079311 azidocodeine C006662 azoaldehyde 1974 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 AZO COMPOUNDS (74-82) *D001547 Benzaldehydes Biochem 13(6):1146;1974 NLM VSR NLM M0049312 azoaldehyde C0602814 4-(2'-imidazolylazo)-benzaldehyde 26437-27-4 T079315 azoaldehyde C006663 azobenzenearsonate-edestin 1974 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ARSENICALS (74-76) *AZOBENZENES (74-76) D010132 p-Azobenzenearsonate *Q000031 analogs ; derivatives D000941 Antigens D010940 Plant Proteins Europ J Immunol 31(5):293;1973 NLM RLS NLM M0049313 azobenzenearsonate-edestin C0602815 0 T079316 azobenzenearsonate-edestin C037372 lead azide 1983 04 04 2000 07 31 2001 2002 explosive used on the tip of an explosive catheter in micro-explosion cystolithotripsy 8 *D001386 Azides *D007854 Lead J Urol 1983;129(1):23 MEG CCR sjn M0113158 lead azide C0064715 13424-46-9 T130 Indicator, Reagent, or Diagnostic Aid T197 Inorganic Chemical T143162 lead azide C015393 5-nitrosalicylaldehyde 1977 01 01 2001 02 07 1998 1999 2000 2001 2001A 2002 4 *ALDEHYDES (77-97) *D001547 Benzaldehydes Clin Chem 23(8):1485;1977 NLM CCR CCR M0064609 5-nitrosalicylaldehyde C0049335 97-51-8 86309-09-3 (potassium) M0064609 M0312811 T094612 5-nitrosalicylaldehyde T094611 2-hydroxy-5-nitrobenzaldehyde M0312811 5-nitrosalicylaldehyde potassium C0952758 86309-09-3 M0064609 M0312811 T342811 5-nitrosalicylaldehyde potassium 1999 08 18 C006668 azophenyl beta-D-lactoside 1974 01 01 1982 09 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 AZO COMPOUNDS (74-81) *D006027 Glycosides D006241 Haptens J Exp Med 140(2):523;1974 NLM VSR NLM M0049326 azophenyl beta-D-lactoside C0602816 beta-D-Glucopyranoside, 4-(phenylazo)phenyl 4-O-beta-D-galactopyranosyl- 56503-35-6 T079329 azophenyl beta-D-lactoside C439974 demethylzeylasterone 2001 12 01 2001 12 01 2002 2002A 2002B from Kokoona zeylanica; structure in first source 1 *D014315 Triterpenes D004250 DNA Topoisomerases, Type II Q000037 antagonists ; inhibitors J Nat Prod 2001 Oct;64(10):1294-6 BMB BMB BMB M0405991 demethylzeylasterone 0 T109 Organic Chemical T121 Pharmacologic Substance T471725 demethylzeylasterone 2001 12 01 C439975 IW 927 cpd 2001 12 01 2002 an inhibitor of tumor necrosis factor receptor type I; structure in first source 1 *D009025 Morpholines Proc Natl Acad Sci U S A 2001 Oct 9;98(21):11879-84 SZM SZM M0405992 IW 927 cpd 0 T109 Organic Chemical T121 Pharmacologic Substance T471726 IW 927 cpd 2001 12 01 T471727 IW927 cpd 2001 12 01 C006684 banamite 1975 01 01 1982 12 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 acaricide ; monoamine oxidase inhibitor 0 *HYDROZONES (75-81) *D006843 Hydrocarbons, Chlorinated Bull Environ Contam Tox 12(2):158;1974 Pesticides 3:298;1975 Survival Toxic Environ WA 670 S693:171;1973 NLM VSR NLM M0049350 banamite C0052948 benzoyl chloride(2,4,6-trichlorophenyl)hydrazone 25939-05-3 T079353 banamite C029681 O-aminoserine 1981 06 11 2000 12 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 RN given refers to cpd without isomeric designation 3 D012694 Serine *Q000031 analogs ; derivatives Anal Biochem 1981;110(2):251 RLS WXM WXM M0094521 O-aminoserine C0069241 1187-83-3 T116 Amino Acid, Peptide, or Protein T130 Indicator, Reagent, or Diagnostic Aid 20311-84-6 ((D)-isomer) 2508-24-9 ((DL)-isomer) 72535-56-9 ((DL)-isomer) M0094521 M0318454 M0094521 M0318456 T124524 O-aminoserine T124523 beta-aminoxyalanine M0318454 O-aminoserine, (D)-isomer C0954828 20311-84-6 T116 Amino Acid, Peptide, or Protein T130 Indicator, Reagent, or Diagnostic Aid M0094521 M0318454 T348454 O-aminoserine, (D)-isomer 1999 08 18 M0318456 O-aminoserine, (DL)-isomer C0954829 72535-56-9 T116 Amino Acid, Peptide, or Protein T130 Indicator, Reagent, or Diagnostic Aid M0094521 M0318456 T348456 O-aminoserine, (DL)-isomer 1999 08 18 C439976 IV 703 cpd 2001 12 01 2002 an inhibitor of tumor necrosis factor receptor type I; structure in first source 1 *D009025 Morpholines Proc Natl Acad Sci U S A 2001 Oct 9;98(21):11879-84 SZM SZM M0405993 IV 703 cpd 0 T109 Organic Chemical T121 Pharmacologic Substance T471728 IV 703 cpd 2001 12 01 T471729 IV703 cpd 2001 12 01 C006694 benzenesulfonylhistamine 1974 01 01 1980 11 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *HISTAMINE (74-75) SULFONES (74-81) D006632 Histamine *Q000031 analogs ; derivatives Surgery 75(2):203;1974 NLM BEJ NLM M0049366 benzenesulfonylhistamine C0602821 0 T079369 benzenesulfonylhistamine C029701 diethylstilbestrol monoglucuronide 1981 05 29 2000 12 19 1998 1999 2000 2001 2001A 2002 metabolite of diethylstilbestrol; RN given refers to (E)-isomer 4 D004054 Diethylstilbestrol *Q000031 analogs ; derivatives CRC Crit Rev Biochem 1981;10(3):171 MEG WXM WXM M0094565 diethylstilbestrol monoglucuronide C0057967 2408-40-4 T110 Steroid T123 Biologically Active Substance 54617-58-2 (mono-Na salt(E)-isomer) M0094565 M0318472 T124568 diethylstilbestrol monoglucuronide T124567 DESBMG M0318472 diethylstilbestrol monoglucuronide, monosodium salt, (E)-isomer C0954832 54617-58-2 T110 Steroid M0094565 M0318472 T348472 diethylstilbestrol monoglucuronide, monosodium salt, (E)-isomer 1999 08 18 C006701 benzocatechol 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 cellulase inhibitor 0 *D002396 Catechols Acta Microbiol Polon 6(3):105;1974 NLM NLM M0049393 benzocatechol C0602823 0 T079396 benzocatechol C006703 benzo(b)fluoranthene 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 22 *D005449 Fluorenes Atmospheric Environ 7(8):819;1973 JN CI 53(6):1713;1974 NLM NLM M0049395 benzo(b)fluoranthene C0053199 3,4-benzfluoranthene 205-99-2 T079398 benzo(b)fluoranthene C006706 benzoperylene 1974 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 see also record for 1,12-benzperylene 6 *BENZANTHRACENES (74-79) D010569 Perylene *Q000031 analogs ; derivatives Health Lab Sci 11(3):228;1974 J Assn Off Anal Chem 59(5):989;1976 NLM RLS NLM M0049398 benzoperylene C0053232 11057-45-7 T079401 benzoperylene C006708 benzoral 1975 01 01 1994 06 15 1995 1996 1997 1998 1999 2000 2001 2002 Russian drug 3 *D011412 Propanolamines Kardiologiia (Mosk) 14(8):93;1974 Kardiologiia (Mosk) 18(4):106;1978 NLM BMB TPW M0049404 benzoral C0053243 1843-82-9 60196-87-4 (maleate) M0049404 M0049403 M0049404 M0309684 T079407 benzoral M0049403 benzodixine C0105638 M0049404 M0049403 T079406 benzodixine M0309684 maleate of benzoral C0895149 60196-87-4 M0049404 M0309684 T339684 maleate of benzoral 1999 08 18 C006709 2H-1,2,4-benzothiadiazine-1,1-dioxide 1970 01 01 1980 11 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 CYCLIC S-OXIDES (70-81) *D001581 Benzothiadiazines Il Farmaco 29(12):910;1974 NLM BEJ NLM M0049405 2H-1,2,4-benzothiadiazine-1,1-dioxide C0046723 359-85-3 T079408 2H-1,2,4-benzothiadiazine-1,1-dioxide C006720 benzyl 6-alpha-acetoxypenicillanate 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PENICILLIN G (74-75) ACETIC ACIDS (74-75) D010400 Penicillin G *Q000031 analogs ; derivatives J Antibiotics 26(11):697;1974 NLM NLM M0049433 benzyl 6-alpha-acetoxypenicillanate C0602830 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(acetyloxy)-3,3-dimethyl-7-oxo-, phenylmethyl ester, (2S-(2alpha,5alpha,6alpha))- 51483-23-9 T079436 benzyl 6-alpha-acetoxypenicillanate C006722 6-benzylamino-1,3-dimethyl-4-N-phenylcytosine 1975 01 01 1980 12 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 BENZYL COMPOUNDS (75-81) D003596 Cytosine *Q000031 analogs ; derivatives Chem Pharm Bull 22(7):1652;1974 NLM BEJ NLM M0049434 6-benzylamino-1,3-dimethyl-4-N-phenylcytosine C0602831 0 T079437 6-benzylamino-1,3-dimethyl-4-N-phenylcytosine C006724 2-benzyl-4-chloromethylthiazole 1975 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 BENZYL COMPOUNDS (75-76) *D013844 Thiazoles Pharmazie 29(7):443;1974 NLM NLM M0049439 2-benzyl-4-chloromethylthiazole C0602832 36916-36-6 T079442 2-benzyl-4-chloromethylthiazole C006733 alpha-benzyl-N-methylphenethylamine 1975 01 01 2000 06 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 impurity by-product of methamphetamine synthesis; identified in illicit methamphetamine samples; structure 6 BENZYL COMPOUNDS (75-76) D008694 Methamphetamine *Q000031 analogs ; derivatives J AOAC 57(5):1147;1974 NLM TWD TWD M0049452 alpha-benzyl-N-methylphenethylamine C0051330 53660-20-1 T109 Organic Chemical T121 Pharmacologic Substance T131 Hazardous or Poisonous Substance T079455 alpha-benzyl-N-methylphenethylamine T079454 ABNMP C006726 N-benzyl-6-dimethyl-8-hydroxy-9-methoxybenzazocine succinate 1974 01 01 1979 10 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D001392 Azocines Jap J Pharmacol (Suppl)24:86;1974 NLM RLS NLM M0049442 N-benzyl-6-dimethyl-8-hydroxy-9-methoxybenzazocine succinate C0602833 0 T079445 N-benzyl-6-dimethyl-8-hydroxy-9-methoxybenzazocine succinate C006758 6-(2-biphenyl)oxy-1,3-dimethyluracil 1974 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *URACIL (74-75) BIPHENYL COMPOUNDS (74-81) D014498 Uracil *Q000031 analogs ; derivatives J Am Chem Soc 96(1):315;1974 NLM TWD TWD M0049489 6-(2-biphenyl)oxy-1,3-dimethyluracil C0602843 0 T079492 6-(2-biphenyl)oxy-1,3-dimethyluracil T079491 6-o-biphenyloxy-1,3-dimethyluracil C080467 Stokoderm Salbe 1993 04 26 2000 06 28 1995 1996 1997 1998 1999 2000 2000A 2001 2002 skin barrier cream which contains stearate, lanolin ; eucoriol (sodium bichlorophenyl sulfamine); protects against skin irritation by organic solvents (acetone, alcohols, gasoline ; turpentine) 2 *D001557 Benzenesulfonates *D007809 Lanolin *D013228 Stearates D004338 Drug Combinations D017453 Dermatitis, Irritant Contact Dermatitis1993 Feb;28(2):94-100 RLS WXM WXM M0215002 Stokoderm Salbe C0658152 0 T109 Organic Chemical T121 Pharmacologic Substance T245007 Stokoderm Salbe T245006 Stokoderm cream C439977 5,7,2',4'-tetrahydroxy-3-geranylflavone 2001 12 01 2001 12 01 2002 2002A from Broussonetia papyrifera (Moraceae); structure in first source 1 *D005419 Flavones D001141 Aromatase Q000037 antagonists ; inhibitors J Nat Prod 2001 Oct;64(10):1286-93 BMB BMB BMB M0405994 5,7,2',4'-tetrahydroxy-3-geranylflavone 0 T109 Organic Chemical T121 Pharmacologic Substance T471730 5,7,2',4'-tetrahydroxy-3-geranylflavone 2001 12 01 C006736 5-benzyloxygramine 1974 01 01 1980 12 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 DIMETHYLAMINES (74-81) *D000470 Alkaloids NLM BEJ NLM M0049458 5-benzyloxygramine C0602835 1453-97-0 T079461 5-benzyloxygramine C078334 BMFA protein 1992 12 24 2001 02 01 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a ubiquitous protein involved in P25 gene regulation in silkworm, Bombyx mori; has been sequenced 2 *D004268 DNA-Binding Proteins D014157 Transcription Factors Mol Cell Biol 1992 Dec;12(12):5768-77 BXB WXM WXM M0210010 BMFA protein C0379778 0 T240015 BMFA protein T240014 BMFA factor C006743 betalactin 1973 01 01 1994 12 08 1995 1996 1997 1998 1999 2000 2001 2002 sterilized milk 0 *MILK (73-94) *D007785 Lactose Cesk Gynecol 38(8):589;1973 NLM PML NLM M0049467 betalactin C0053519 0 T079470 betalactin C007375 diethylene glycol distearate 1974 01 01 2000 06 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 2 *GLYCOLS (74-77) STEARIC ACID (74-77) *D005026 Ethylene Glycols J Histochem Cytochem 22(1):29;1974 NLM TWD TWD M0050537 diethylene glycol distearate C0057948 109-30-8 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T080540 diethylene glycol distearate C010536 Andursil 1975 01 01 2001 10 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2000B 2000C 2000D 2001 2001A 2002 contains aluminum hydroxide, magesium hydroxide, magnesium carbonate ; dimethylpolsiloxane; RN given refers to liquid form 4 *MAGNESIUM (75-77) *D000536 Aluminum Hydroxide *D004129 Dimethylpolysiloxanes *D008276 Magnesium Hydroxide D004338 Drug Combinations Praxis 64(26):843;1975 NLM TWD TWD M0056098 Andursil C0051836 55874-20-9 T121 Pharmacologic Substance T197 Inorganic Chemical 55874-19-6 (tablet form) M0056098 M0056097 T086101 Andursil M0056097 Brimos C0107173 0 T104 Chemical Viewed Structurally T121 Pharmacologic Substance M0056098 M0056097 T086100 Brimos C078400 yellow fever virus envelope protein E 1992 12 27 2001 02 01 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 has homology to human pancreatic amylase; aa sequence has been determined 10 *D014759 Viral Envelope Proteins D015005 Yellow fever virus Eur J Clin Chem Clin Biochem 1992 Aug;30(8):449-54 RLS WXM WXM M0210155 yellow fever virus envelope protein E C0379784 0 T240160 yellow fever virus envelope protein E T240159 YFVEPE C084977 TAF(II)70 protein 1994 01 25 2002 04 18 1996 1997 1998 1999 2000 2001 2001A 2001B 2002 2002A 2002B TBP - TATA-binding protein; TAF - TBP-associated factor; human homolog of Drosophila TAFII60; TAFII70 ; TAFII80 are identical; interactions of both with other subunits of TFIID are conserved; amino acid sequence given in first ; second source 13 *D014157 Transcription Factors EMBO J 1993 Dec 15;12(13):5303-9 Proc Natl Acad Sci U S A 1995 Aug 29;92(18):8195-9 BMB TWD TWD M0225696 TAF(II)70 protein C0380088 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance M0225696 M0403403 M0225696 M0225693 T255701 TAF(II)70 protein T255699 TAFII70 T255700 hTAFII70 M0403403 hTAF(II)80delta T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance M0225696 M0403403 T468134 hTAF(II)80delta 2001 10 27 M0225693 TAF(II)80 C0380087 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance M0225696 M0225693 T255698 TAF(II)80 C044850 1-myristoyl-2-(12-N-(4-azido-2-nitrophenyl)aminododecanoyl)phosphatidylcholine 1985 04 18 2001 10 05 1997 1998 1999 2000 2001 2001A 2001B 2002 2 *D001386 Azides *D010713 Phosphatidylcholines FEBS Lett 1985;182(1):176 RLS TWD TWD M0130737 1-myristoyl-2-(12-N-(4-azido-2-nitrophenyl)aminododecanoyl)phosphatidylcholine C0044486 71303-93-0 T119 Lipid T130 Indicator, Reagent, or Diagnostic Aid T160742 1-myristoyl-2-(12-N-(4-azido-2-nitrophenyl)aminododecanoyl)phosphatidylcholine T160740 1-myristoyl-2-(12-N-(4-azido-2-nitrophenyl)aminododecanoyl)-sn-glycero-3-phosphocholine T160741 PL I C412063 helicase, lymphoid specific 2000 08 16 2001 10 05 2000 2001 2001A 2001B 2002 A lymphoid specific helicase, expressed in early thymocytes; a proliferation-associated SNF2-like gene; amino acid sequence in first source 2 *DNA-BINDING PROTEINS (2000-2001) *TRANSCRIPTION FACTORS (2000-2001) *D004265 DNA Helicases Cancer Res 2000 Jul 1;60(13):3612-22 SZM jmp jmp M0389585 helicase, lymphoid specific C0966658 EC 5.99.- T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T449696 helicase, lymphoid specific 2001 06 08 T281138 Hells gene product T281140 Lsh gene product T281142 lymphoid-specific Hel protein T421888 PASG protein 2000 08 16 T421889 PASG gene product 2000 08 16 C006763 2,4-bis(bromomethyl)estrone methyl ether 1974 01 01 1982 09 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ESTRANES (74-79) *ESTROGENS/antag (74-79) D004970 Estrone *Q000031 analogs ; derivatives Steroids 24(1):63;1974 NLM VSR NLM M0049502 2,4-bis(bromomethyl)estrone methyl ether C0602844 2,4-bis(bromomethyl)-3-methoxy-1,3,5(10)-estratrien-17-one 53464-61-2 T079505 2,4-bis(bromomethyl)estrone methyl ether C006769 bis(copper(II)-D-penicillamine disulfide)nonahydrate 1974 01 01 1980 12 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *COPPER (74-81) *PENICILLAMINE (74-75) ORGANOMETALLIC COMPOUNDS (74-81) D010396 Penicillamine *Q000031 analogs ; derivatives J Am Chem Soc 96(3):726;1974 NLM RLS NLM M0049509 bis(copper(II)-D-penicillamine disulfide)nonahydrate C0602848 Copper, diaquabis(mu-((3,3'-dithiobis(D-valinato))(2-)))di-, heptahydrate, stereoisomer 52022-66-9 T079512 bis(copper(II)-D-penicillamine disulfide)nonahydrate C006771 N,N'-bis(dichloroacetyl)-1,12-diaminododecane 1974 01 01 1998 11 09 1999 2000 2001 2002 0 ACETAMIDES (76-81) *D003959 Diamines J Membrane Biol 10(3):237;1973 Myo Cardial Biol 4:233;1974 NLM BQV NLM M0049513 N,N'-bis(dichloroacetyl)-1,12-diaminododecane C0067294 26108-85-0 T079516 N,N'-bis(dichloroacetyl)-1,12-diaminododecane C006775 bis(methylguanidinium)monohydrogen orthophosphate 1974 01 01 1980 12 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ORGANOPHOSPHORUS COMPOUNDS (74-81) *D006146 Guanidines J Am Chem Soc 96(14):4471;1974 NLM BEJ NLM M0049519 bis(methylguanidinium)monohydrogen orthophosphate C0602852 41480-89-1 T079522 bis(methylguanidinium)monohydrogen orthophosphate C006777 bis(4-nitrophenyl)carbonate 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *NITROBENZENES (74-75) *D009596 Nitrophenols Biochemistry 13(1):70;1974 NLM NLM M0049522 bis(4-nitrophenyl)carbonate C0602853 5070-13-3 T079525 bis(4-nitrophenyl)carbonate C006778 bisnordethiobiotin 1974 01 01 1980 12 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 catabolic 2-carbon shorter analog of dethiobiotin 0 PROPIONATES (74-81) *D007093 Imidazoles Biochim Biophys Acta 326(3):485;1973 NLM BEJ NLM M0049523 bisnordethiobiotin C0602854 21561-97-7 T079526 bisnordethiobiotin C006781 bis(thioacetoxy)aurate 1974 01 01 1998 01 05 1998 1999 2000 2001 2002 structure 0 ACETIC ACIDS (74-81) *D009942 Organometallic Compounds D006046 Gold J Histochem Cytochem 22(4):252;1974 NLM IDX BVL M0049527 bis(thioacetoxy)aurate C0602856 Aurate(1-), bis(ethanethioato-O,S)- 52579-82-5 T079530 bis(thioacetoxy)aurate C006784 bleomycinic acid 1974 01 01 1995 07 18 1996 1997 1998 1999 2000 2001 2002 structure 0 *BLEOMYCIN (74-75) *BLEOMYCINS (76-95) CARBOXYLIC ACIDS (74-75) D001761 Bleomycin *Q000031 analogs ; derivatives J Antibiot 26(2):117;1973 NLM BVL BVL M0049531 bleomycinic acid C0602857 37364-66-2 T079534 bleomycinic acid C006790 boxazin 1974 01 01 1980 12 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination of acetylsalicylic acid ; ascorbic acid 0 *D001205 Ascorbic Acid *D001241 Aspirin D004338 Drug Combinations Acta Univ Carol (Med Monogr) 52(0):194;1972 NLM BEJ NLM M0049543 boxazin C0602859 56333-48-3 T079546 boxazin UD 20;181 k C078423 IR6 protein 1992 12 29 2001 02 01 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; 272 amino acid residues, MW 30.1 kDa; from equine herpesvirus type I 6 *D014764 Viral Proteins Virology 1992 Dec;191(2):649-60 BXB WXM WXM M0210206 IR6 protein C0210951 146314-51-4 T240211 IR6 protein T240210 IR6 gene product C436223 dimethyl-3,6-dichloro-2,5-dihydroxyterephthalate 2001 10 05 2001 2002 structure in first source 1 *D010795 Phthalic Acids J Am Chem Soc 2001 Feb 28;123(8):1713-22 SZM SZM M0400783 dimethyl-3,6-dichloro-2,5-dihydroxyterephthalate 0 T109 Organic Chemical T464812 dimethyl-3,6-dichloro-2,5-dihydroxyterephthalate 2001 10 05 T464813 DM-DC-DHTP 2001 10 05 C006803 5'-O-(N-bromoacetyl-4-aminophenylphosphoryl)-3'-N-L-phenylalanylpuromycin aminonucleoside 1974 01 01 1983 08 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PUROMYCIN (74-75) NUCLEOTIDES (74-75) D011692 Puromycin Aminonucleoside *Q000031 analogs ; derivatives Biochem Biophys Res Commun 55(1):117;1973 NLM JSL NLM M0049578 5'-O-(N-bromoacetyl-4-aminophenylphosphoryl)-3'-N-L-phenylalanylpuromycin aminonucleoside C0602871 0 M0049578 M0049577 T079581 5'-O-(N-bromoacetyl-4-aminophenylphosphoryl)-3'-N-L-phenylalanylpuromycin aminonucleoside M0049577 5'-O-(N-bromoacetyl-p-aminophenylphosphoryl)-3'-N-L-phenylalanylpuromycin aminonucleoside C0602870 M0049578 M0049577 T079580 5'-O-(N-bromoacetyl-p-aminophenylphosphoryl)-3'-N-L-phenylalanylpuromycin aminonucleoside C006808 (3-(4-bromoacetylpyridinio)propyl)adenosine pyrophosphate 1974 01 01 1983 06 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structural analog of NAD 0 *ADENINE NUCLEOTIDES (74-77) PYRIDINIUM COMPOUNDS (74-77) D000244 Adenosine Diphosphate *Q000031 analogs ; derivatives FEBS Letters 34(2):175;1973 Z Naturforsch 13(1-2):85;1977 NLM DLJ NLM M0049585 (3-(4-bromoacetylpyridinio)propyl)adenosine pyrophosphate C0043602 Adenosine 5'-(trihydrogen diphosphate), mono(3-(4-(bromoacetyl)pyridinio)propyl) ester, hydroxide, inner salt 36097-68-4 T079588 (3-(4-bromoacetylpyridinio)propyl)adenosine pyrophosphate C006814 5-bromodeoxycytidine 5'-monophosphate 1974 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *DEOXYRIBONUCLEOTIDES (74-78) DEOXYCYTIDINE (74-78) D003843 Deoxycytidine Monophosphate *Q000031 analogs ; derivatives Proc Nat Acad Sci USA 70(12):3788;1973 NLM RLS NLM M0049589 5-bromodeoxycytidine 5'-monophosphate C0602878 6674-56-2 T079592 5-bromodeoxycytidine 5'-monophosphate C006815 551-D-1 1975 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 piperidineacetyl deriv of dihydrobenzoxazole cpd 0 *OXAZINES (75-80) PIPERIDINES (75-82) *D010080 Oxazoles Arzneim Forsch 24(12):2053;1974 NLM VSR NLM M0049590 551-D-1 C0602879 0 T079593 551-D-1 C006818 alpha-bromohydrin 1974 01 01 1997 07 10 1998 1999 2000 2001 2002 structure 2 BROMINE (74-82) *D011409 Propylene Glycols Cancer Res 36(9):3369;1976 J Reprod Fert 38(2):379;1974 NLM NNS BVL M0049594 alpha-bromohydrin C0051333 4704-77-2 T079597 alpha-bromohydrin C006819 bromomonamycin 1973 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D000900 Antibiotics Antimicrob Ag Chemother 3(3):380;1973 NLM NLM M0049595 bromomonamycin C0602883 0 T079598 bromomonamycin C006822 4'-bromosalicylanilide 1974 01 01 1997 11 20 1998 1999 2000 2001 2002 photoproduct from UV-irradiation of tribromsalan; structure 0 *SALICYLAMIDES (74-77) ANILINE COMPOUNDS (74-77) *D012458 Salicylanilides J Invest Dermatol 63(2):227;1974 NLM BQV NLM M0049607 4'-bromosalicylanilide C0602884 2627-77-2 T079610 4'-bromosalicylanilide C054709 ardisiacrispin B 1988 03 07 2001 09 05 2002 untero-contracting oleanane triterpene saponin form Ardisia crispa; structure given in first source 2 *D012503 Saponins *D014315 Triterpenes D029591 Myrsinaceae Planta Med 1987;53(5):415 RLS ssb sjn M0154324 ardisiacrispin B C0632636 Oleanan-29-al, 3- ((O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-beta-D-glucopyranosyl-(1-4)-O-(beta-D-glucopyranosyl-(1-2))-alpha-L-arabinopyranosyl)oxy)-13,28-epoxy-16-hydroxy-, (3beta,16alpha,20beta)- 112766-96-8 T110 Steroid T121 Pharmacologic Substance T184329 ardisiacrispin B T184328 3 beta -O-(alpha-L-rhamnopyranosyl-(1-2)-O-beta-D-glucopyranosyl-(1-4)-(O-beta-D-glucopyranosyl-(1-2))-alpha-L-arabinopyranosyl)-16 alpha-hydroxy-13 beta,28-epoxyolean-30-al C006852 butralin 1974 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 2 NITRO COMPOUNDS (74-81) *D000814 Aniline Compounds Bull Environ Contam Toxicol 20(2):170;1978 J Agric Food Chem 22(4):689;1974 J Agric Food Chem 24(2):424;1976 NLM TWD TWD M0049654 butralin C0054269 4-(1,1-dimethylethyl)-N-(1-methylpropyl)-2,6-dinitrobenzenamine 33629-47-9 T079657 butralin T079656 N-sec-butyl-4-tert-butyl-2,6-dinitroaniline C087033 thioxoalanylproline 4-nitroanilide 1994 05 30 2001 02 01 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure in first source 1 *D000813 Anilides *D004151 Dipeptides Eur J Biochem 1994 Apr 1;221(1):455-61 THA CCR CCR M0230599 thioxoalanylproline 4-nitroanilide C0254320 0 T260604 thioxoalanylproline 4-nitroanilide T260603 thioxoalanyl-proline 4-nitroanilide T260602 Ala-psi(CS-N)-Pro-NH-Np C006830 bucarpolate 1969 01 01 1980 12 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 BENZOATES (74-81) *D004149 Dioxoles NLM BEJ NLM M0049620 bucarpolate C0602889 2-(2-butoxyethoxy)ethyl ester piperonylic acid 136-63-0 T079623 bucarpolate C006835 bufarenogin 1974 01 01 1980 12 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 HYDROXSTERIODS (74-81) *D002018 Bufanolides Helv Chim Acta 56(1):2827;1973 NLM BEJ NLM M0049626 bufarenogin C0602893 17008-65-0 T079629 bufarenogin C006849 alpha-((tert-butylamino)methyl)-3,4-dihydroxybenzyl alcohol-3,4-di(4-toluate)methanesulfonate 1975 01 01 2000 11 06 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 TOSYL COMPOUNDS (75-81) *D000605 Amino Alcohols Int Arch Allergy 47(5):633;1974 NLM TWD TWD M0049651 alpha-((tert-butylamino)methyl)-3,4-dihydroxybenzyl alcohol-3,4-di(4-toluate)methanesulfonate C0602900 Benzoic acid, 4-methyl-, 4-(2-((1,1-dimethylethyl)amino)-1-((methylsulfonyl)oxy)ethyl)-1,2-phenylene ester 76741-89-4 T109 Organic Chemical T121 Pharmacologic Substance T079654 alpha-((tert-butylamino)methyl)-3,4-dihydroxybenzyl alcohol-3,4-di(4-toluate)methanesulfonate T079653 alpha-((tert-butylamino)methyl)-3,4-dihydroxybenzyl alcohol-3,4-di(p-toluate)methanesulfonate C090597 succinic acid mono-3-amino-2,4,6-triiodo-N-ethylanilide 1994 12 26 2001 02 01 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 *D000813 Anilides *D013386 Succinates D007462 Iodobenzenes Invest Radiol 1994 Jul;29(7):689-94 THA CCR CCR M0239376 succinic acid mono-3-amino-2,4,6-triiodo-N-ethylanilide C0291211 1634-73-7 2666-11-7 (Na salt) M0239376 M0326779 T269381 succinic acid mono-3-amino-2,4,6-triiodo-N-ethylanilide T269380 MATEA-succinic acid M0326779 succinic acid mono-3-amino-2,4,6-triiodo-N-ethylanilide, sodium salt C0970864 2666-11-7 M0239376 M0326779 T356779 succinic acid mono-3-amino-2,4,6-triiodo-N-ethylanilide, sodium salt 1999 08 18 C067469 mast cell protease 6 1991 03 25 2001 07 19 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2001B 2001C 2002 expressed by bone marrow derived mast cells; mature enzyme contains 245 amino acids; amino acid sequence given in first source 22 *D012697 Serine Endopeptidases D008407 Mast Cells J Biol Chem 1991;266(6):3847 RLS CCR CCR M0184913 mast cell protease 6 C0286961 EC 3.4.21.- T214918 mast cell protease 6 T429611 MMCP-6 2000 11 25 T214917 mast cell protease-6 T214916 MMCProteinase-6 T429187 MCP-6 (protease) 2000 11 20 C092092 alanyl-phenylalanyl-psi(CS-N)-prolyl-phenylalanyl-4-nitroanilide 1995 03 17 2001 02 01 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence in first source 1 *D000813 Anilides *D009842 Oligopeptides Electrophoresis 1994 Aug-Sep;15(8-9):1151-7 THA CCR CCR M0243146 alanyl-phenylalanyl-psi(CS-N)-prolyl-phenylalanyl-4-nitroanilide C0294398 0 T273151 alanyl-phenylalanyl-psi(CS-N)-prolyl-phenylalanyl-4-nitroanilide T273150 Ala-Phe-psi(CS-N)-Pro-Phe-4-nitroanilide T273149 A4P4NO2A C006851 N-n-butylbarbital 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D001463 Barbiturates J Pharmacol Exp Therap 190(2):384;1974 NLM NLM M0049652 N-n-butylbarbital C0602901 1-n-butyl-5,5-diethylbarbituric acid 15517-26-7 T079655 N-n-butylbarbital C093089 glycylproline 3,5-dibromo-4-hydroxyanilide 1995 05 17 2001 02 01 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 *D000813 Anilides *D004151 Dipeptides J Clin Lab Anal 1995;9(2):113-8 PML CCR CCR M0245548 glycylproline 3,5-dibromo-4-hydroxyanilide C0296509 0 T275553 glycylproline 3,5-dibromo-4-hydroxyanilide T275551 Gly-Pro-DBAP T275552 glycyl-L-proline 3,5-dibromo-4-hydroxyanilide C006856 butyletharine 1974 01 01 1994 06 15 1995 1996 1997 1998 1999 2000 2001 2002 N-t-butyl analog of isoetharine; structure 0 *AMINO ALCOHOLS (74-75) CATECHOL (74-75) D007528 Isoetharine *Q000031 analogs ; derivatives Arch Int Pharmacod 205(1):144;1973 NLM BMB TPW M0049660 butyletharine C0602902 1-(3,4-dihydroxyphenyl)-2-tert-butyl-1-butanol.HCl 51264-24-5 T079663 butyletharine C419307 n-(3-chloro-2-hydroxypropyl)trimethylammonium 2001 02 01 2001 2002 1 *D000644 Ammonium Compounds Appl Biochem Biotechnol. 2000 Jun;87(3):233-45 BMB BMB M0377675 n-(3-chloro-2-hydroxypropyl)trimethylammonium C0963721 0 T109 Organic Chemical T434877 n-(3-chloro-2-hydroxypropyl)trimethylammonium 2001 02 01 T434878 Cl-HPTMA 2001 02 01 T434879 n-(3-chloro-2-hydroxypropyl)-trimethylammonium chloride 2001 02 01 C006861 butyl(2-oxopropyl)nitrosamine 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 *D009602 Nitrosamines Gann 65(1):13;1974 NLM NLM M0049667 butyl(2-oxopropyl)nitrosamine C0602903 51938-15-9 T079670 butyl(2-oxopropyl)nitrosamine C084775 fenspiride 1994 10 12 2001 07 20 1999 2000 2001 2001A 2002 was heading 1975-94 (see under SPIRO COMPOUNDS 1975-90); use SPIRO COMPOUNDS to search FENSPIRIDE 1975-94; bronchodilator agent used in asthma 13 Oxazoles (72-74) Piperidines (72-74) Spiro Compounds (72-74) *D013141 Spiro Compounds TPW CCR CCR M0225164 fenspiride C0015843 1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-(2-phenylethyl)- 5053-06-5 M0225164 M0225159 M0225164 M0225163 M0225164 M0225161 M0225164 M0225162 T255169 fenspiride M0225159 3612 S C0288541 M0225164 M0225159 T255164 3612 S T255165 3612-S M0225163 decaspiride C0288542 M0225164 M0225163 T255168 decaspiride M0225161 Espiran C0014882 M0225164 M0225161 T255166 Espiran M0225162 Pneumorel C0032324 M0225164 M0225162 T255167 Pneumorel C100669 UC 82 1996 08 30 2001 02 01 1996 1997 1998 1999 2000 2001 2001A 2002 a thiocarboxanilide pentenyloxy ether derivative; structure given in first source 1 *D000813 Anilides *D013876 Thiophenes Mol Pharmacol 1996 Aug;50(2):394-401 PML CCR CCR M0264152 UC 82 C0391450 0 M0264152 M0264150 T294157 UC 82 T294156 UC-82 M0264150 2-chloro-5-(((2-methyl-3-thienyl)carbonothioyl)amino)phenyl 3-methyl-2-butenyl ether C0391449 M0264152 M0264150 T294155 2-chloro-5-(((2-methyl-3-thienyl)carbonothioyl)amino)phenyl 3-methyl-2-butenyl ether C098064 INK4D protein, human 1996 03 11 2001 09 05 2002 cyclin D-dependent kinase inhibitor; inhibits cdk4 and cdk6; 86% identical to murine INK4d; amino acid sequence in first source 53 *Carrier Proteins (1995-2001) *D019941 Protein p16 D018844 Cyclin-Dependent Kinases Q000037 antagonists ; inhibitors Genomics 1995 Oct 10;29(3):623-30 THA nns sjn M0257668 INK4D protein, human C0386669 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance D004791 Enzyme Inhibitors T287673 INK4D protein, human T287670 CDKN2D gene product T287671 INK4D gene product, human T287672 p19(INK4D) C001107 MON 0856 1972 01 01 2001 02 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 MALONATES (72-76) NITRILES (72-82) *D000814 Aniline Compounds J Econ Entomol 165(1):48;1972 NLM CCR CCR M0041201 MON 0856 C0601008 propanedinitrile, (((3,5-bis(trifluoromethyl)phenyl)ethylamino)methylene)- 18181-26-5 M0041201 M0041199 T071204 MON 0856 T071203 MON-0856 M0041199 (3,5-di(alpha,alpha,alpha-trifluoromethyl)-N-ethylanilino)methylenemalononitrile C0601006 M0041201 M0041199 T071202 (3,5-di(alpha,alpha,alpha-trifluoromethyl)-N-ethylanilino)methylenemalononitrile C006880 camphidine 1975 01 01 1981 01 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 AZA COMPOUNDS (75-81) *D001892 Bornanes Farmaco(Sci) 29(1):37;1974 NLM BEJ NLM M0049697 camphidine C0602911 1,8,8-trimethyl-3-azabicyclo(3.2.1)octane 465-49-6 T079700 camphidine C085571 S 12340 1994 03 01 2001 07 20 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 2 *D013141 Spiro Compounds D011341 Probucol *Q000031 analogs ; derivatives Eur J Pharmacol 1993 Oct 1;248(3):263-72 PML CCR CCR M0227045 S 12340 C0251324 1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-(3-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)thio)propyl)- 144754-35-8 M0227045 M0227041 T257050 S 12340 T257048 S-12340 T257049 S12340 M0227041 8-(3-(3,5-di-tert-butyl-4-hydroxyphenylthio)propyl)-1-oxa-2-oxo-3,8-diazaspiro(4.5)decane C0251323 M0227045 M0227041 T257046 8-(3-(3,5-di-tert-butyl-4-hydroxyphenylthio)propyl)-1-oxa-2-oxo-3,8-diazaspiro(4.5)decane T257047 8-(3-(3,5-diterbutyl-4-hydroxyphenylthio)propyl)-1-oxa-2-oxo-3,8-diazaspiro(4.5)decane C010415 N-phenylacetyl-4-nitroaniline 1975 01 01 2001 02 01 1999 2000 2001 2001A 2002 2 NITRO COMPOUNDS (75-79) PHENYLACETATES (75-82) *D000814 Aniline Compounds Folia Microbiol (Praha) 20:224;1975 NLM CCR CCR M0055902 N-phenylacetyl-4-nitroaniline C0282961 Benzeneacetamide, N-(4-nitrophenyl)- 13140-77-7 T085905 N-phenylacetyl-4-nitroaniline T085903 N-phenylacetyl-p-nitroaniline T085904 phenylacetic acid p-nitroanilide C012173 4-amino-N-acetyl-N-methylaniline 1976 01 01 2001 02 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 *D000814 Aniline Compounds Cancer Res 36(5):1568;1976 NLM CCR CCR M0059054 4-amino-N-acetyl-N-methylaniline C0605140 119-63-1 T089057 4-amino-N-acetyl-N-methylaniline T089055 p-amino-N-acetyl-N-methylaniline T089056 para-amino-N-acetyl-N-methylaniline C006890 caracurine 1974 01 01 1982 09 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 calabash curarine; structure 0 *D003472 Curare Chem Biol Interactions 6(6):355;1973 NLM VSR NLM M0049709 caracurine C0602913 466-85-3 T079712 caracurine C419308 cetearyl alcohol 2001 02 01 2001 2002 1 *D005233 Fatty Alcohols D017449 Dermatitis, Allergic Contact Contact Dermatitis. 2000 Sep;43(3):174-5 BMB BMB M0377676 cetearyl alcohol C0971350 67762-27-0 T109 Organic Chemical T434880 cetearyl alcohol 2001 02 01 T434881 cetyl-stearyl alcohol 2001 02 01 T434882 1-octadecanol, mixed with 1-hexadecanol 2001 02 01 C012322 fluchloralin 1976 01 01 2001 02 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 11 DINITROBENZENES (76-82) *D000814 Aniline Compounds J Agric Food Chem 1979;27(6):1148 Pesticides 3:277;1975 NLM CCR CCR M0059277 fluchloralin C0060478 N-(2-chloroethyl)-N-propyl-2,6-dinitro-4-trifluoromethylaniline 33245-39-5 M0059277 M0059275 T089280 fluchloralin T089279 N-(2-chloroethyl)-2,6-dinitro-N-propyl-4-(trifluoromethyl)aniline M0059275 Basalin C0105240 M0059277 M0059275 T089278 Basalin C006911 S-carboxymethyl-thiopyruvate 1974 01 01 1982 09 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 oxidative deamination product of S-carboxymethylcysteine; structure 0 SULFIDES (74-82) *D003998 Dicarboxylic Acids Mol Cell Biochem 3(1):3;1974 NLM VSR NLM M0049754 S-carboxymethyl-thiopyruvate C0602920 Propanoic acid, 3-((carboxymethyl)thio)-2-oxo- 51783-05-2 T079757 S-carboxymethyl-thiopyruvate C006915 Cardioplegin 1974 01 01 1987 09 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 pharmacoplegic agent for producing cardiac standstill in open-heart surgery; contains procaine, magnesium L-asparaginate ; sorbitol 9 *ASPARAGINE (74-79) *MAGNESIUM (74-78) D001224 Aspartic Acid D011343 Procaine D013012 Sorbitol D002314 Cardioplegic Solutions J Cardiovasc Surg 19(2):193;1978 Kard Pol 16(4):299;1973 Khirurgiia(Sofia) 1979;32(4):290 Langenbecks Arch Chir suppl 1979;p.29 Langenbecks Arch Chir:99;1978 NLM PEH NLM M0049761 Cardioplegin C0054792 Magnesate(2-), bis(L-aspartato(2-)-N,O1)-, (T-4)-, dihydrogen, mixt. with 2-(diethylamino)ethyl 4-aminobenzoate monohydrochloride 68245-15-8 T079764 Cardioplegin UD 23:95 o C006918 carococculine 1975 01 01 1981 06 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 alkaloid from Cocculus carolinus (sinomenine type); structure 0 *MORPHINANS (75-81) *D000470 Alkaloids J Nat Prod 37(3):488;1974 NLM NBM NLM M0049762 carococculine C0602921 54302-44-2 T079765 carococculine C006920 caroxin F 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 fluorocarbon liquid 1 *HYDROCARBONS, FLUORINATED (74-76) *D005466 Fluorocarbons Anesthesiol 40(6):566;1974 J Appl Physiol 39(4):603;1975 NLM NLM M0049767 caroxin F C0054822 perfluoro-1-isopropoxy-hexane 37340-18-4 T079770 caroxin F C006955 cetiedil 1975 01 01 2000 09 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 RN given refers to parent cpd; structure 64 *THIOPHENES (75-82) *D001381 Azepines Arch Ostet Ginecol 1978;83(3-4):127 Blood 1980;55(2):265 Boll Soc Ital Biol Sper 54(3):233;1978 Clin Ter 1979;90(1):11 Eur J Clin Pharmacol 12:205;1977 Int J Clin Pharm Biopharm 16(9):402;1978 J Pharmacol Exp Ther 198(1):176;1976 Kardiologiia 18(8):37;1978 Lille Med 18(10)suppl 5:1303;1973 Nouve Presse Med 5(25):1577;1976 NLM CCR CCR M0049814 cetiedil C0055146 alpha-cyclohexyl-3-thiopheneacetic acid, 2-(hexahydro-1H-azepin-1-yl)ethyl ester 14176-10-4 T109 Organic Chemical T121 Pharmacologic Substance D000889 Anti-Arrhythmia Agents D000986 Antisickling Agents D014665 Vasodilator Agents 16199-90-9 (HCl) 16286-69-4 (citrate[1:1]) 86683-24-1 (oxalate) M0049814 M0309759 M0049814 M0309758 M0049814 M0309760 M0049814 M0049813 T079817 cetiedil Merck Index, 9th ed, p. 253 UD 25:189n M0309759 cetiedil citrate (1:1) C0951575 16286-69-4 T109 Organic Chemical T121 Pharmacologic Substance M0049814 M0309759 T339759 cetiedil citrate (1:1) 1999 08 18 M0309758 cetiedil hydrochloride C0951574 16199-90-9 T109 Organic Chemical T121 Pharmacologic Substance M0049814 M0309758 T339758 cetiedil hydrochloride 1999 08 18 M0309760 cetiedil oxalate C0951576 86683-24-1 T109 Organic Chemical T121 Pharmacologic Substance M0049814 M0309760 T339760 cetiedil oxalate 1999 08 18 M0049813 Stratene C0143709 T109 Organic Chemical T121 Pharmacologic Substance M0049814 M0049813 T079816 Stratene C091408 MDL 73975 1995 02 06 2001 07 20 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a 5-HT(1A) receptor agonist 1 *D013141 Spiro Compounds Eur J Pharmacol 1994 Sep 12;262(3):205-15 THA CCR CCR M0241385 MDL 73975 C0292937 0 M0241385 M0241381 T271390 MDL 73975 T271387 MDL 73,975 T271388 MDL-73,975 T271389 MDL-73975 M0241381 8-(2-(2,3-dihydro-8-methoxy-1,4-benzodoxin-2-yl)methylamino)ethyl-8-azaspiro(4,5)decane-7,9-dione hydrochloride C0292935 M0241385 M0241381 T271386 8-(2-(2,3-dihydro-8-methoxy-1,4-benzodoxin-2-yl)methylamino)ethyl-8-azaspiro(4,5)decane-7,9-dione hydrochloride C006926 casimiroedine 1974 01 01 1982 09 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 *ALKALOIDS (74-79) *IMIDAZOLES (74-79) *D008761 Methylhistamines *D009705 Nucleosides J Am Chem Soc 95(26):8737;1973 NLM VSR NLM M0049779 casimiroedine C0602923 4-(2-(N-methyl-N-trans-cinnamoylamino)ethyl)-1- beta-D-glucopyranosylimidazole 5853-02-1 T079782 casimiroedine Merck Index, 9th ed, p. 240 C006927 Cassella 7657 1974 01 01 1998 05 14 1998 1999 2000 2001 2002 0 *MORPHOLINES (74-82) *D003374 Coumarins Arch Int Pharmacodyn Ther 206(2):299;1973 NLM BQV NLM M0049780 Cassella 7657 C0602924 3-(gamma-morpholino-beta-(3',4',5'-trimethoxybenzyloxy)propyl-4-methyl-7,8-dimethoxycoumarin.HCl 52591-15-8 T079783 Cassella 7657 C006936 celestosamine 1975 01 01 2001 01 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *DEOXY SUGARS (81-82) DEOXY SUGARS (75-81) *D000606 Amino Sugars J Antibiotics 27(8):642;1974 NLM TWD TWD M0049791 celestosamine C0602928 D-erythro-D-galacto-Octose, 6-amino-6,8-dideoxy-7-O-methyl- 75919-70-9 T079794 celestosamine T079793 6-amino-6,8-dideoxy-7-0-methyl-D-erythro-D- galacto-octose C006934 cecekin vitrum 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D005768 Gastrointestinal Hormones Gut 14(10):763;1973 NLM NLM M0049789 cecekin vitrum C0602926 9012-22-0 T079792 cecekin vitrum C070827 4-azidoaniline 1991 10 09 2001 02 01 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd 2 *D000814 Aniline Compounds *D001391 Azo Compounds Biochemistry 1991;30(35):8605 RLS CCR CCR M0192697 4-azidoaniline C0647823 14860-64-1 91159-79-4 (HCl) M0192697 M0325431 T222702 4-azidoaniline T222701 para-azidoaniline M0325431 4-azidoaniline hydrochloride C0958743 91159-79-4 M0192697 M0325431 T355431 4-azidoaniline hydrochloride 1999 08 18 C074798 4-aminooctoylphenone 1992 06 28 2001 02 01 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source; protects against the effects of cyanide on hemoglobin 1 *D000814 Aniline Compounds *D007659 Ketones Gen Pharmacol 1992 Jan;23(1):19-25 THA CCR CCR M0201820 4-aminooctoylphenone C0651780 63884-78-6 T231825 4-aminooctoylphenone T231824 para-aminooctoylphenone T231823 4-PAOP C077066 4-(2-(4-(((3,5-dichloroanilino)carbonyl)methyl)phenoxy)-2-methylpropionic acid) 1992 10 30 2001 02 01 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 allosteric effector of hemoglobin; structure given in first source 5 *D000814 Aniline Compounds *D011426 Propionic Acids Biochemistry 1992 Sep 29;31(38):9141-9 RLS CCR CCR M0207108 4-(2-(4-(((3,5-dichloroanilino)carbonyl)methyl)phenoxy)-2-methylpropionic acid) C0173075 131179-94-7 M0207108 M0207106 T237113 4-(2-(4-(((3,5-dichloroanilino)carbonyl)methyl)phenoxy)-2-methylpropionic acid) M0207106 RSR 4 C0173074 M0207108 M0207106 T237111 RSR 4 T237112 RSR-4 C006949 ceramide pentasaccharide 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *CEREBROSIDES (74-76) OLIGOSACCHARIDES (74-76) *D006028 Glycosphingolipids J Biol Chem 249(4):1022;1974 NLM NLM M0049805 ceramide pentasaccharide C0602931 0 T079808 ceramide pentasaccharide C006951 cerberin 1975 01 01 1982 09 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *CARDANOLIDES (75-79) *D002298 Cardenolides D002301 Cardiac Glycosides Chinese Med J 10:642;1974 NLM VSR NLM M0049806 cerberin C0055101 3-((4-0-acetyl-6-deoxy-3-0-methyl-alpha-L-glucopyranosyl)oxy)-14-hydroxy-(3 beta,5 beta)-card- 20(22)-enolide 25633-33-4 T079809 cerberin Merck Index, 9th ed, p. 250 C008380 metamizil 1974 01 01 2000 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 RN given refers to parent cpd; structure 14 *BENZILATES (74-78) DIETHYLAMINES (74-78) D001535 Benactyzine *Q000031 analogs ; derivatives Endodrinologie 71(2):149;1978 Horm Brain Funct:WL300:1601H:243;1971 Klin Med (Mosk) 56(9):113;1978 Klin Med(Mosk) 1979;57(9):59 Pharmacol Biochem Behav 2(1):1;1974 Vestn Dermatol Venerol 1979;9:3 Vrach Delo 3:122;1978 Zh Nevropatol Psikhiatr 78(3):365;1978 Zh Vyssh Nerv Deiat 26(1):181;1976 NLM CCR CCR M0052180 metamizil C0066050 57-36-3 T109 Organic Chemical T121 Pharmacologic Substance 10503-18-1 (HCl) M0052180 M0310271 T082183 metamizil Negwer 3830 T082180 metamyzil T082181 methamisil T082182 methylbenactyzine M0310271 metamizil hydrochloride C0951837 10503-18-1 T109 Organic Chemical T121 Pharmacologic Substance M0052180 M0310271 T340271 metamizil hydrochloride 1999 08 18 T082179 beta-diethylaminopropylbenzilic acid ester, hydrochloride C082410 azalanstat 1993 08 28 2001 02 01 1996 1997 1998 1999 2000 2001 2001A 2002 inhibits lanosterol 14 alpha-demethylase, the enzyme which catalyzes the first step in conversion of lanosterol to cholesterol in mammals; structure given in first source 5 *D000814 Aniline Compounds *D013440 Sulfides J Med Chem 1993 Jul 23;36(15):2235-7 RLS CCR CCR M0219604 azalanstat C0218596 Benzenamine, 4-(((2-(2-(4-chlorophenyl)ethyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methyl)thio)-, (2S-cis)- 143393-27-5 M0219604 M0219602 T249609 azalanstat USAN (1995) M0219602 RS 21607 C0949115 M0219604 M0219602 T249607 RS 21607 T249608 RS-21607 C006960 chelex 1970 01 01 1998 01 06 1998 1999 2000 2001 2002 46 *D011137 Polystyrenes *D011145 Polyvinyls D007475 Ion Exchange Resins NLM BQV NLM M0049822 chelex C0055279 80208-96-4 D002614 Chelating Agents T079825 chelex CIAF C006961 chilaphylin 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 produced by Streptomyces melanosporofaciens strain chilea 0 *D000900 Antibiotics J Antibiotics 26(3):126;1973 NLM NLM M0049823 chilaphylin C0602933 Chilaphylin 39405-40-8 T079826 chilaphylin C006963 chlamydocin 1974 01 01 1982 10 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 8 ETHERS, CYCLIC (74-79) D010456 Peptides, Cyclic Europ J Cancer 10(12):801;1974 Helv Chim Acta 57(3):533;1974 NLM VSR NLM M0049826 chlamydocin C0055325 53342-16-8 T079829 chlamydocin C006966 chlorcolchicine 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *COLCHICINE (74-75) CHLORINE (74-76) D003078 Colchicine *Q000031 analogs ; derivatives Schweiz Med Wochenschr 104(8):265;1974 NLM NLM M0049828 chlorcolchicine C0602935 26279-89-0 T079831 chlorcolchicine C084408 2-methyl-4,6-bis(N,N-dimethylaminophenyl)pyrylium 1993 12 22 2001 02 01 1997 1998 1999 2000 2001 2001A 2002 RN refers to iodide; structure given in first source 3 *D000814 Aniline Compounds *D011714 Pyrans Nucleic Acids Symp Ser 1993;(29):83-4 THA CCR CCR M0224255 2-methyl-4,6-bis(N,N-dimethylaminophenyl)pyrylium C0249164 151921-86-7 M0224255 M0224254 T254260 2-methyl-4,6-bis(N,N-dimethylaminophenyl)pyrylium T254258 2-Me-bis(diMeNHPh)pyrylium M0224254 2-methyl-4,6-bis(N,N-dimethylaminophenyl)pyrylium iodide C0249163 M0224255 M0224254 T254259 2-methyl-4,6-bis(N,N-dimethylaminophenyl)pyrylium iodide C084409 2-methyl-4,6-bis-(N,N-dimethylaminophenyl)thiopyrylium 1993 12 22 2001 02 01 1997 1998 1999 2000 2001 2001A 2002 RN refers to iodide; structure given in first source 1 *D000814 Aniline Compounds *D013876 Thiophenes Nucleic Acids Symp Ser 1993;(29):83-4 THA CCR CCR M0224258 2-methyl-4,6-bis-(N,N-dimethylaminophenyl)thiopyrylium C0662591 151921-87-8 M0224258 M0224257 T254263 2-methyl-4,6-bis-(N,N-dimethylaminophenyl)thiopyrylium T254261 2-Me-bis(diMeNHPh)thiopyrylium M0224257 2-methyl-4,6-bis-(N,N-dimethylaminophenyl)thiopyrylium iodide C0662590 M0224258 M0224257 T254262 2-methyl-4,6-bis-(N,N-dimethylaminophenyl)thiopyrylium iodide C006975 N-chloroacetyltyramine 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *TYRAMINE (74-75) ACETIC ACIDS (74-75) D014439 Tyramine *Q000031 analogs ; derivatives J Am Chem Soc 96(8):2564;1974 NLM NLM M0049841 N-chloroacetyltyramine C0602937 Acetamide, 2-chloro-N-(2-(4-hydroxyphenyl)ethyl)- 52399-83-4 T079844 N-chloroacetyltyramine C112826 quillaic acid 3-O-xylopyranosyl-1-3-(galactopyranosyl-1-2)glucopyranosiduronic acid 1998 07 03 2001 04 19 1998 1999 2000 2001 2001A 2002 isolated from Quillaja saponaria; structure in first source 1 *D012503 Saponins Phytochemistry 1998 May;48(1):175-80 THA TWD TWD M0291630 quillaic acid 3-O-xylopyranosyl-1-3-(galactopyranosyl-1-2)glucopyranosiduronic acid C0676132 0 T321635 quillaic acid 3-O-xylopyranosyl-1-3-(galactopyranosyl-1-2)glucopyranosiduronic acid T321634 quillaic acid 3-O-XylGalGlcUA C006979 2-chloro-ATP 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 new ATP analog; relaxes mammalian gut preparations; structure 12 *ATP (74-75) CHLORINE (74-75) D000255 Adenosine Triphosphate *Q000031 analogs ; derivatives J Med Chem 16(10):1188;1973 NLM NLM M0049850 2-chloro-ATP C0046004 2-chloroadenosine-5-triphosphate 49564-60-5 T079853 2-chloro-ATP C006980 chlorobactene 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D002338 Carotenoids Biochem J 136(2):395;1973 NLM NLM M0049851 chlorobactene C0602940 2932-09-4 T079854 chlorobactene C085691 2,6-diethylaniline 1994 03 08 2001 02 01 1998 1999 2000 2001 2001A 2002 one of the major metabolites of the herbicide alachlor 6 *D000814 Aniline Compounds Toxicology 1993 Dec 31;85(2-3):117-22 PML CCR CCR M0227362 2,6-diethylaniline C0251561 579-66-8 71477-82-2 (HCl) M0227362 M0326467 T257367 2,6-diethylaniline T257366 2,6-DEA M0326467 2,6-diethylaniline hydrochloride C0959426 71477-82-2 M0227362 M0326467 T356467 2,6-diethylaniline hydrochloride 1999 08 18 C006985 16-alpha-chloroestrone methyl ether 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ESTRANES (74-75) 17-KETOSTEROIDS (74-75) D004970 Estrone *Q000031 analogs ; derivatives NLM NLM M0049863 16-alpha-chloroestrone methyl ether C0602943 16-alpha-chloro-3-methoxy-estra-1,3,5,(10)-trien-17- one 4091-75-2 T079866 16-alpha-chloroestrone methyl ether C006988 6-chloro-9-(6-deoxy-beta-L-lyxo-hexopyranosylulose)purine 1974 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 shows activity against KB cells; structure 0 KETOSES (74-82) *D011684 Purine Nucleosides Carbohyd Res 30(1):192;1973 NLM VSR NLM M0049865 6-chloro-9-(6-deoxy-beta-L-lyxo-hexopyranosylulose)purine C0602945 50615-82-2 T079868 6-chloro-9-(6-deoxy-beta-L-lyxo-hexopyranosylulose)purine C006990 4-chloro-beta,beta-difluoroamphetamine 1974 01 01 1990 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *AMPHETAMINE (74-75) AMPHETAMINE/*analogs (75-76) *D000662 Amphetamines Arch Int Pharmacodyn 208(2):274;1974 NLM TBT NLM M0049867 4-chloro-beta,beta-difluoroamphetamine C0602947 37410-86-9 T079870 4-chloro-beta,beta-difluoroamphetamine C086624 4-(4-N,N-dimethylaminophenyl)but-3-en-2-one 1994 05 05 2001 02 01 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to compound with no isomeric designation; structure given in first source 1 *D000814 Aniline Compounds *D002074 Butanones Mutat Res 1994 Apr 1;306(1):71-80 PML CCR CCR M0229644 4-(4-N,N-dimethylaminophenyl)but-3-en-2-one C0253515 5432-53-1 30625-58-2 ((E)-isomer) M0229644 M0326522 T259649 4-(4-N,N-dimethylaminophenyl)but-3-en-2-one T259648 DMAPB M0326522 4-(4-N,N-dimethylaminophenyl)but-3-en-2-one, (E)-isomer C0959458 30625-58-2 M0229644 M0326522 T356522 4-(4-N,N-dimethylaminophenyl)but-3-en-2-one, (E)-isomer 1999 08 18 C090913 N-benzylidene-4-chloroaniline 1995 01 12 2001 02 01 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 *D000814 Aniline Compounds J Pharm Pharmacol 1994 Jul;46(7):585-90 PML CCR CCR M0240212 N-benzylidene-4-chloroaniline C0291932 780-21-2 T270217 N-benzylidene-4-chloroaniline T270215 4-chloro-N-(phenylmethylene)benzeneamine T270216 NBE4CA C006998 chloroisobutyronitrile 1974 01 01 1982 06 30 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 BUTYRATES (74-82) HYDROCARBONS, CHLORINATED (74-79) *D009570 Nitriles J Pharm Soc Jap 93(10):1274;1973 NLM CHA NLM M0049886 chloroisobutyronitrile C0055417 0 T079889 chloroisobutyronitrile C007001 2-chloromercuri-4,6-dinitrophenol 1974 01 01 1982 08 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *DINITROPHENOLS (74-77) *MERCURY (74-77) *ORGANOMETALLIC CPDS (74-75) *D002730 Chloromercurinitrophenols D013439 Sulfhydryl Reagents Arch Int Physiol Biochem 81(2):366;1973 NLM CHA NLM M0049891 2-chloromercuri-4,6-dinitrophenol C0046026 24579-91-7 T079894 2-chloromercuri-4,6-dinitrophenol C007003 10-chloro-2-methoxy-5-methyl-7H-pyrrolo(3,2,1-d,e)phenanthrid-7-one-4-acetic acid 1974 01 01 1986 08 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 rigid analog of indomethacin; structure 0 PYRROLES (74-82) *D010617 Phenanthridines J Med Chem 17(2):167;1974 NLM THA NLM M0049892 10-chloro-2-methoxy-5-methyl-7H-pyrrolo(3,2,1-d,e)phenanthrid-7-one-4-acetic acid C0602949 51806-88-3 T079895 10-chloro-2-methoxy-5-methyl-7H-pyrrolo(3,2,1-d,e)phenanthrid-7-one-4-acetic acid C007013 6-chloro-9-(1,4-oxathian-2-yl)-9H-purine 1974 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 potential as antitumor or insecticidal ; acaricidal activity; structure 0 *HETEROCYCLIC COMPOUNDS (74-79) OXATHIINS (74-82) *D011687 Purines Carbohyd Res 30(1):225;1973 NLM VSR NLM M0049906 6-chloro-9-(1,4-oxathian-2-yl)-9H-purine C0602956 0 T079909 6-chloro-9-(1,4-oxathian-2-yl)-9H-purine C007014 6-chloro-9-(1,4-oxathian-3-yl)-9H-purine 1974 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 potential as antitumor or insecticidal ; acaricidal activity; structure 0 *HETEROCYCLIC COMPOUNDS (74-79) OXATHIINS (74-82) *D011687 Purines Carbohyd Res 30(1):225;1973 NLM VSR NLM M0049907 6-chloro-9-(1,4-oxathian-3-yl)-9H-purine C0602957 0 T079910 6-chloro-9-(1,4-oxathian-3-yl)-9H-purine C078845 cycMs1 protein 1993 01 25 2001 02 01 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; isolated from alfalfa; shows 25-35% homology with cyclins of all types; a true cell division marker at the mRNA level; expressed in young leaves but not in mature leaves 1 *D010940 Plant Proteins *D016213 Cyclins Plant Cell 1992 Dec;4(12):1531-8 THA WXM WXM M0211246 cycMs1 protein C0656382 0 T241251 cycMs1 protein T241250 cycMs1 gene product C007021 4-chloropropionanilide 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 PROPIONATES (74-75) *D000813 Anilides Biochem Pharmacol 22(20):2565;1973 NLM NLM M0049931 4-chloropropionanilide C0048205 2759-54-8 T079934 4-chloropropionanilide C007023 1-chloro-3-(2-propynyloxy)-2-propanol 1974 01 01 1995 08 28 1996 1997 1998 1999 2000 2001 2002 structure 0 *ALCOHOL, PROPYL (74-75) ALKYNES (74-82) *D002728 Chlorohydrins J Pharm Sci 62(11):1894;1973 NLM MLH BVL M0049936 1-chloro-3-(2-propynyloxy)-2-propanol C0602960 2-Propanol, 1-chloro-3-(2-propynyloxy)- 18180-29-5 T079939 1-chloro-3-(2-propynyloxy)-2-propanol C099402 delta-tonoplast intrinsic protein 1996 06 21 2001 05 03 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 aquaporin isolated from Arabidopsis; amino acid sequence in first source; GenBank U39486 5 *D010940 Plant Proteins *D018272 Porins Plant Cell 1996 Apr;8(4):587-99 THA CCR CCR M0260896 delta-tonoplast intrinsic protein C0389481 0 T290901 delta-tonoplast intrinsic protein T290900 delta-TIP T412014 So-deltaTIP 2000 04 15 C412287 cell-elongating factor, Vibrio cholerae 2000 08 21 2000 2001 2002 causes elongation of Chinese hamster ovary (CHO) cells; amino acid sequence in first source 1 *D001427 Bacterial Toxins D014734 Vibrio cholerae Microb Pathog 2000 Jul;29(1):1-8 BMB BMB M0368341 cell-elongating factor, Vibrio cholerae C0916626 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T422255 cell-elongating factor, Vibrio cholerae 2000 08 21 T422256 cell-elongating toxin, Vibrio cholerae 2000 08 21 T422257 Vibrio cholerae CEF 2000 08 21 T422258 85-kDa CEF 2000 08 21 C007019 5-(4-chlorophenyl)silatrane 1975 01 01 2001 01 30 1996 1997 1998 1999 2000 2001 2001A 2002 rodenticide against rats ; mice; structure 0 *BICYCLO COMPOUNDS (94-95) *SILICON (75-93) *D017646 Organosilicon Compounds *D019086 Bicyclo Compounds, Heterocyclic J Hygiene 73(1):39;1974 NLM TWD TWD M0049918 5-(4-chlorophenyl)silatrane C0049004 1-(p-chlorophenyl)-2,8,9-trioxa-5-aza-1-silabicyclo(3.3.3)undecane 29025-67-0 T079921 5-(4-chlorophenyl)silatrane T079920 5-(p-chlorophenyl)silatrane C078909 YopB protein 1993 01 28 2001 02 01 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from Yersinia; 401 aa residues, MW about 42 kDa; aa sequence given in first source 30 *D001425 Bacterial Outer Membrane Proteins Infect Immun 1993 Jan;61(1):71-80 BXB WXM WXM M0211393 YopB protein C0211901 0 T241398 YopB protein T241397 yopB gene product C007067 cinepazide maleate 1974 01 01 2001 07 30 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 systemic, coronary ; cerebral vasodilator agent; see also record for cinepazide (parent cpd); structure 7 *PYRROLIDINES (74-81) CINNAMATES (74-77) *D010879 Piperazines Ann Pharm Fr 35(7-8):265;1977 Arzneim Forsch 26(8):1565-69;1976 Bibl Anat 1978;18:141 Lille Med 21 suppl 4:898;1976 Lille Med 21(7) suppl 3:629;1976 Nippon Yakurigaku Zasshi 1979;75(5):495 Nippon Yakurigaku Zasshi 1979;75(5):507 No To Shinkei 31(6):621;1979 Therapie 29(1):29;1974 Xenobiotica 6(7):441;1976 NLM TWD TWD M0050019 cinepazide maleate C0055741 1-(2-oxo-2-(1-pyrrolidinyl)ethyl)-4-(1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)piperazine (Z)-2-butenedioate (1:1) 26328-04-1 M0050019 M0050017 M0050019 M0050018 T080022 cinepazide maleate Merck Index, 9th ed, p. 292,#2282 UD 25:107c UD 26:68q T080019 1-((1-pyrrolidynylcarbonyl)methyl)-4-(3,4,5-trimethoxycinnamoyl)piperazine maleate M0050017 67350-MD C0099468 M0050019 M0050017 T080020 67350-MD M0050018 Vasodistal C0148212 M0050019 M0050018 T080021 Vasodistal C007047 christofin 1975 01 01 1982 09 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 isolated from Rubia tinctorum L.; structure 0 ETHOXY COMPOUNDS (75-79) *D000880 Anthraquinones Pharmazie 29(7):478;1974 NLM VSR NLM M0049978 christofin C0602968 1,4-dihydroxy-2-ethoxymethylanthraquinone 53755-57-0 T079981 christofin C091456 2,5-difluoroaniline 1995 02 10 2001 02 01 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 1 *D000814 Aniline Compounds Chem Biol Interact 1995 Jan;94(1):49-72 BMB CCR CCR M0241524 2,5-difluoroaniline C0293048 367-30-6 T271529 2,5-difluoroaniline T271527 2,5-difluoroaminobenzene T271528 2,5-difluorobenzenamine C007056 chrysophenine 1969 01 01 1998 05 14 1998 1999 2000 2001 2002 0 *STILBENES (69-82) *D001391 Azo Compounds NLM BQV NLM M0049986 chrysophenine C0602971 4,4'-bis((p-ethoxyphenyl)azo)-2,2'-stilbenesulfonic acid disodium salt 2870-32-8 T079989 chrysophenine C007061 C.I. Fluorescent Brightening Agent 28 1969 01 01 1997 10 22 1997 1998 1999 2000 2001 2002 129 *STILBENES (69-82) *D001557 Benzenesulfonates Arch De Vecchi Anat Patol 58(1-3):409;1973 NLM BMB BVL M0049998 C.I. Fluorescent Brightening Agent 28 C0054393 4,4'-bis((4-anilino-6-(bis(2-hydroxyethyl)amino)-s-triazin-2-yl)amino)-2,2'-stilbene disulfonic acid 4404-43-7 D003287 Contrast Media D005456 Fluorescent Dyes M0049998 M0049996 M0049998 M0049994 M0049998 M0049993 M0049998 M0049997 M0049998 M0049995 T080001 C.I. Fluorescent Brightening Agent 28 M0049996 calcofluor white M2R C0282851 M0049998 M0049996 T079999 calcofluor white M2R M0049994 calcofluor white C0108160 M0049998 M0049994 T079997 calcofluor white M0049993 Tinopal LPW C0602972 M0049998 M0049993 T079996 Tinopal LPW M0049997 calcofluor white ST C0108162 M0049998 M0049997 T080000 calcofluor white ST M0049995 calcofluor white M 2R C0108161 M0049998 M0049995 T079998 calcofluor white M 2R C078910 YopD protein 1993 01 28 2001 02 01 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from Yersinia; 306 aa residues, MW about 33 kD; aa sequence given in first source 31 *D001425 Bacterial Outer Membrane Proteins Infect Immun 1993 Jan;61(1):71-80 BXB WXM WXM M0211395 YopD protein C0211903 0 T241400 YopD protein T241399 yopD gene product C023423 AI 3-35765 1980 04 03 2001 07 31 1996 1997 1998 1999 2000 2000A 2001 2001A 2002 5 *D010880 Piperidines J Med Entomol 1979;16(6):524 MEG TWD TWD M0080657 AI 3-35765 C0051024 1-(3-cyclohexen-1-ylcarbonyl)piperidine 52736-58-0 M0080657 M0351442 T110660 AI 3-35765 T110658 AI-3-35765 T110659 AI3-35765 M0351442 2 piperidines-1-(3-cyclohexen-1-ylcarbonyl)piperidine C0897905 M0080657 M0351442 T401159 2 piperidines-1-(3-cyclohexen-1-ylcarbonyl)piperidine 1999 12 01 C092367 NC 1005 1995 04 03 2001 02 01 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure in first source 1 *D000814 Aniline Compounds *D011812 Quinuclidines Gen Pharmacol 1994 Oct;25(6):1149-56 THA CCR CCR M0243818 NC 1005 C0294983 0 M0243818 M0243816 T273823 NC 1005 T273822 NC-1005 M0243816 N-(azabicyclo(2.2.2)octan-3-yl)methyl-N-(2-indanyl)aniline hydrochloride C0294982 M0243818 M0243816 T273821 N-(azabicyclo(2.2.2)octan-3-yl)methyl-N-(2-indanyl)aniline hydrochloride C092368 NC 1006 1995 04 03 2001 02 01 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure in first source 1 *D000814 Aniline Compounds *D011812 Quinuclidines Gen Pharmacol 1994 Oct;25(6):1149-56 THA CCR CCR M0243821 NC 1006 C0294985 0 M0243821 M0243819 T273826 NC 1006 T273825 NC-1006 M0243819 N-(azabicyclo(2.2.2)octan-2-yl)methyl-N-(2-indanyl)aniline hydrochloride C0294984 M0243821 M0243819 T273824 N-(azabicyclo(2.2.2)octan-2-yl)methyl-N-(2-indanyl)aniline hydrochloride C099233 FCE 27677 1996 06 10 2001 02 01 1998 1999 2000 2001 2001A 2002 structure in first source 3 *D000814 Aniline Compounds *D010671 Phenylurea Compounds D002785 Sterol O-Acyltransferase Q000037 antagonists ; inhibitors J Lipid Res 1996 Jan;37(1):1-14 THA CCR CCR M0260522 FCE 27677 C0389147 0 M0260522 M0260521 T290527 FCE 27677 T290525 FCE-27677 M0260521 N-(2,6-bis(1-methylethyl)phenyl)-N'-(2-(4-dimethylaminophenyl)-4,5-dimethyldioxolan-2-yl)methylurea hydrochloride C0389148 M0260522 M0260521 T290526 N-(2,6-bis(1-methylethyl)phenyl)-N'-(2-(4-dimethylaminophenyl)-4,5-dimethyldioxolan-2-yl)methylurea hydrochloride C078913 77-kD merozoite protein, Babesia 1993 01 28 2001 02 01 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; from B. bovis 2 *D015800 Protozoan Proteins D000953 Antigens, Protozoan Infect Immun 1993 Jan;61(1):236-44 BXB WXM WXM M0211402 77-kD merozoite protein, Babesia C0211910 151472-22-9 T241407 77-kD merozoite protein, Babesia T241406 Bb-1 protein, Babesia C007081 citrus red No. 2 1969 01 01 1998 01 05 1998 1999 2000 2001 2002 0 NAPHTHOLS (69-82) *D001391 Azo Compounds NLM IDX NLM M0050037 citrus red No. 2 C0602979 1-(2,5-dimethoxyphenylazo)-2-naphthol 6358-53-8 T080040 citrus red No. 2 C007096 cobalt-9-methyladenine 1974 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ADENINE (74-75) *ORGANOMETALLIC COMPOUNDS (74-82) COBALT (74-82) D000225 Adenine *Q000031 analogs ; derivatives Biochim Biophys Acta 324(2):301;1973 NLM VSR NLM M0050060 cobalt-9-methyladenine C0602980 Cobalt, dichloro(9-methyl-9H-purin-6-amine-N(1))-, homopolymer, stereoisomer 52639-70-0 T080063 cobalt-9-methyladenine C007097 cobalt(II)-stellacyanin 1974 01 01 1987 03 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 PLANT PROTEINS (74-82) *D008667 Metalloproteins *D009942 Organometallic Compounds D003035 Cobalt Proc Nat Acad Sci USA 71(4):1339;1974 NLM PEH NLM M0050061 cobalt(II)-stellacyanin C0282855 0 T080064 cobalt(II)-stellacyanin C007099 cobramine B 1974 01 01 1978 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PROTEINS (74-78) *SNAKE VENOMS (75-78) *D004179 Direct Lytic Factors Arch Biochem Biophys 156(1):71;1973 NLM NLM M0050064 cobramine B C0602981 12777-56-9 T080067 cobramine B C007114 conopharyngine pseudoindoxyl 1974 01 01 1981 06 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 from Tabernamontana pachysiphon Stapf. var cumminsii (Staph.) H. Huber 0 INDOLES (74-81) *D000470 Alkaloids J Pharm Pharmacol 25(10):820;1973 NLM NBM NLM M0050094 conopharyngine pseudoindoxyl C0602983 52579-71-2 T080097 conopharyngine pseudoindoxyl C007116 convicine 1974 01 01 1990 12 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 13 *GLUCOSIDES (78-82) *PYRIMIDINE NUCLEOSIDES (74-78) *PYRIMIDINONES (77-78) GLUCOSE (74-78) URACIL/*analogs (78-91) D014529 Uridine *Q000031 analogs ; derivatives J Chem Soc 10(0):1089;1973 J Sci Fd Agr 29(4):323;1978 NLM RLS NLM M0050095 convicine C0056266 6-amino-5-beta-D-glucopyranosyloxyuracil 19286-37-4 T080098 convicine C007118 copper-bis-N,N,-dihydroxyethylglycine 1974 01 01 1998 01 06 1998 1999 2000 2001 2002 0 *COPPER (74-82) GLYCINE (74-75) D005998 Glycine *Q000031 analogs ; derivatives Comp Gen Pharmacol 4(16):315;1973 NLM BQV NLM M0050098 copper-bis-N,N,-dihydroxyethylglycine C0602984 54873-37-9 T080101 copper-bis-N,N,-dihydroxyethylglycine C007126 coriolan 1975 01 01 1983 07 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 polysaccharide from Coriolus versicolor Composed of 1-2 or 1-6 linked glucopyranose residues 1 *POLYSACCHARIDES (75-79) GLUCOSE (75-79) *D005936 Glucans Folia Pharm Jpn 72(1):77;1976 Jpn J Pharmacol 1979;29(6):953 NLM DLJ NLM M0050113 coriolan C0056339 54328-34-6 T080116 coriolan C007127 coriolin 1974 01 01 1982 07 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 sesquiterpene antibiotic isolated from Coriolus consors; structure in third source 6 D012717 Sesquiterpenes J Antibiotics (Tokyo) 27(4):301;1974 J Antibiotics (Tokyo) 30(1):59;1977 NLM CHA NLM M0050114 coriolin C0056340 (1a alpha,3R*,3a beta,3b alpha,4 alpha,6a alpha,7 beta,7aS*)-hexahydro-4,7-dihydroxy-3a,5,5-trimethylspiro(cyclopenta(4,5)pentaleno(1,6a-b)oxirene-3(3aH),2'-oxiran)-2-(1aH)-one 33404-85-2 T080117 coriolin C007128 coriose 1975 01 01 1982 02 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *KETOSES (75-82) *D006539 Heptoses Chem Pharm Bull 22(7):1624;1974 NLM NBM NLM M0050115 coriose C0602985 D-altro-3-heptulose 13059-96-6 T080118 coriose C007187 cyclo-CTP 1974 01 01 2001 01 30 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *CYTOSINE NUCLEOTIDES (74-79) ANHYDRIDES (74-79) *D009712 Nucleotides, Cyclic D003570 Cytidine Triphosphate *Q000031 analogs ; derivatives Biochem Pharmacol 22(22):2829;1973 NLM TWD TWD M0050224 cyclo-CTP C0603006 Triphosphoric acid, P-((2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-6H-furo(2',3':4,5)oxazolo(3,2-a)pyrimidin-2-yl)methyl) ester, monohydrochloride, (2R-(2alpha,3beta,3abeta,9abeta))- 76248-24-3 T080227 cyclo-CTP T080226 cyclocytidine 5'-triphosphate C028458 tipepidine 1981 03 19 2001 07 31 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd 5 *D010880 Piperidines Minerva Pediatr 1980;32(12):818 RLS TWD TWD M0091581 tipepidine C0076714 5169-78-8 14698-07-8 (citrate[1:1]) M0091581 M0317755 M0091581 M0091579 M0091581 M0091580 T121584 tipepidine Merck Index, 9th ed, #9177 Negwer, 5th ed, #2797 USAN 1981, p.380 M0317755 tipepidine citrate (1:1) C0954492 14698-07-8 M0091581 M0317755 T347755 tipepidine citrate (1:1) 1999 08 18 M0091579 tipepidine hibenzate C0145968 M0091581 M0091579 T121582 tipepidine hibenzate M0091580 tipepidine ibenzato C0145969 M0091581 M0091580 T121583 tipepidine ibenzato C079429 Etl-1 protein 1993 02 26 2001 09 05 2002 from mouse; shows specific beta-galactosidase staining during development; may be involved in gene regulating pathways during development; amino acid sequence given in second source 3 *PROTEINS (93) *D009687 Nuclear Proteins D014157 Transcription Factors Mech Dev 1992 Nov;39(1-2):111-23 Mech Dev 1992 Nov;39(1-2):95-109 RLS WXM sjn M0212617 Etl-1 protein C0212892 0 T242622 Etl-1 protein T242621 enhancer trap locus 1 protein C007151 S-crotonyl-N-acetylcysteamine 1974 01 01 1982 09 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *CYSTEAMINE (74-75) CROTONATES (74-82) D003543 Cysteamine *Q000031 analogs ; derivatives Biochemical J 135(3):385;1973 NLM VSR NLM M0050160 S-crotonyl-N-acetylcysteamine C0376797 23784-20-5 T080163 S-crotonyl-N-acetylcysteamine C050216 9-(1-hydroxy-4-phosphinyl-2-butoxymethyl)guanine 1986 11 19 2001 07 31 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 3 GUANINE/*analogs and derivatives (86-97) D015774 Ganciclovir *Q000031 analogs ; derivatives Antiviral Res 1986;6(5):299 THA CCR CCR M0143524 9-(1-hydroxy-4-phosphinyl-2-butoxymethyl)guanine C0245002 104880-60-6 M0143524 M0143521 T173529 9-(1-hydroxy-4-phosphinyl-2-butoxymethyl)guanine T173525 HPBMG M0143521 SR 3773 C0526113 M0143524 M0143521 T173526 SR 3773 T173527 SR-3773 T173528 SR3773 C007154 crotyl phosphate 1974 01 01 1997 07 11 1998 1999 2000 2001 2002 structure 0 *ORGANOPHOSPHORUS COMPOUNDS (74-82) *D000440 Butanols Xenobiotica 1(1):55;1971 NLM ADP BVL M0050164 crotyl phosphate C0602993 33170-77-3 T080167 crotyl phosphate C110878 SA 6541 1998 03 17 2001 02 01 1998 1999 2000 2001 2001A 2002 inhibits leukotriene A4 hydrolase; structure in first source 3 *D000814 Aniline Compounds D003545 Cysteine *Q000031 analogs ; derivatives Biochem Pharmacol 1998 Feb 1;55(3):297-304 THA CCR CCR M0287324 SA 6541 C0671919 0 M0287324 M0287322 T317329 SA 6541 T317328 SA-6541 M0287322 S-(4-dimethylaminobenzyl)-N-(3-mercapto-2-methylpropionyl)cysteine C0671917 M0287324 M0287322 T317327 S-(4-dimethylaminobenzyl)-N-(3-mercapto-2-methylpropionyl)cysteine C007157 cryolite 1974 01 01 1982 09 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 7 *FLUORIDES (74-77) ALUMINUM (74-82) SODIUM (74-77) *D012969 Sodium Fluoride Gig Sanit (Moskva) 38(4):14;1973 NLM VSR NLM M0050167 cryolite C0056543 sodium aluminum fluoride 15096-52-3 T080170 cryolite C007159 cryptopine 1974 01 01 1981 06 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 4 DIOXOLES (74-81) *D000470 Alkaloids J AOAC 58(5):888;1975 NLM NBM NLM M0050169 cryptopine C0056553 12,13,14,15,-tetrahydro-9,10-dimethoxy-14-methylbenzo(e)-1,3-dioxolo(4,5-1)(2)benzazecin-7(6H)-one 482-74-6 T080172 cryptopine C079440 Mxi1 protein 1993 02 27 2001 02 01 1996 1997 1998 1999 2000 2001 2001A 2002 specifically interacts with Max protein to bind Myc-Max recognition sites; amino acid sequence given in first source 57 *D004268 DNA-Binding Proteins *D014157 Transcription Factors D018257 Helix-Loop-Helix Motifs Cell 1993 Jan 29;72(2):223-32 RLS WXM WXM M0212641 Mxi1 protein C0212910 0 T242646 Mxi1 protein T242645 Max interactor 1 C038408 CP 46665 1983 07 11 2001 07 31 1998 1999 2000 2001 2001A 2002 immunomodulator; RN given refers to di-HCl 17 *D010880 Piperidines Ann Surg 1983;198(1):53 MEG TWD TWD M0115627 CP 46665 C0056437 72618-10-1 M0115627 M0115624 T145631 CP 46665 UD 34:4m T145629 CP 46665-1 T145630 CP-46,665 M0115624 4-aminomethyl-1-(2,3-bis(decyloxy)propyl)-4-phenylpiperidine C0096717 M0115627 M0115624 T145628 4-aminomethyl-1-(2,3-bis(decyloxy)propyl)-4-phenylpiperidine C098785 WRN protein 1996 04 30 2001 11 24 1998 1999 2000 2001 2001A 2002 2002A the protein responsible for Werner's syndrome, an inherited disease with clinical symptoms resembling premature aging; a DNA-dependent ATPase and a 3'-5' helicase; possesses exonuclease motifs; shows 62-64% identity to human RECQL; amino acid sequence given in first source 119 *D004265 DNA Helicases D014898 Werner Syndrome D009687 Nuclear Proteins D000251 Adenosinetriphosphatase D005092 Exonucleases Science 1996 Apr 12;272(5259):258-62 PML THA THA M0259453 WRN protein C0388246 EC 5.99.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T289458 WRN protein T289456 WRN gene product T289457 WS gene product C079480 RAG2 protein 1993 03 01 2001 02 01 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; a rice seed allergenic protein 69 *D010940 Plant Proteins D000485 Allergens Plant Mol Biol 1993 Jan;21(2):239-48 THA WXM WXM M0212733 RAG2 protein C0212979 0 D014361 Trypsin Inhibitors T242738 RAG2 protein T242737 RAG2 gene product C007172 5-cyano-2-furaldehyde 1974 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *FURALDEHYDE (74-75) NITRILES (74-82) D005662 Furaldehyde *Q000031 analogs ; derivatives J Pharm Soc Jpn 93(11):1526;1973 NLM VSR NLM M0050198 5-cyano-2-furaldehyde C0602998 42061-89-2 T080201 5-cyano-2-furaldehyde C007179 cyathins 1974 01 01 1982 09 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 class of antibiotics produced by Cyathus species Basidiomycetes 2 BASIDIOMYCETES (74-82) *D000900 Antibiotics Hindustan Antibiotics 16(1):9;1973 NLM VSR NLM M0050213 cyathins C0602999 Cyathin 12626-46-9 T080216 cyathins C007184 cyclo-CDP 1974 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CYTOSINE NUCLEOTIDES (74-78) *D009712 Nucleotides, Cyclic D003565 Cytidine Diphosphate *Q000031 analogs ; derivatives Biochem Pharmacol 22(22):2829;1973 NLM RLS NLM M0050220 cyclo-CDP C0603003 cyclocytidine 5'-diphosphate 5511-94-4 T080223 cyclo-CDP C007185 cyclo-CMP 1974 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CYTOSINE NUCLEOTIDES (74-75) *D009712 Nucleotides, Cyclic D003568 Cytidine Monophosphate *Q000031 analogs ; derivatives Biochem Pharmacol 22(22):2829;1973 NLM RLS NLM M0050221 cyclo-CMP C0603004 cyclocytidine 5'-monophosphate 39679-56-6 T080224 cyclo-CMP C007195 cyclohexylphenylketone 1974 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *BENZOATES (74-79) *D003510 Cyclohexanes Acta Pol Pharm 31(1):53;1974 NLM NLM M0050229 cyclohexylphenylketone C0603008 712-50-5 T080232 cyclohexylphenylketone C007196 cyclohexylserine 1974 01 01 1995 09 20 1995 1996 1997 1998 1999 2000 2001 2002 serine antagonist; structure 0 HYDROXYLAMINES (74-82) *D003509 Cyclohexanecarboxylic Acids J Nat Cancer Inst 51(3):761;1973 NLM BVL NLM M0050230 cyclohexylserine C0603009 1-(hydroxylamino)cyclohexanecarboxylic acid 5524-43-6 T080233 cyclohexylserine C007197 5',2-O-cyclo,2'3'-O-isopropylidene uridine 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *URIDINE (74-75) D014529 Uridine *Q000031 analogs ; derivatives Biochim Biophys Acta 340(4):472;1974 NLM NLM M0050231 5',2-O-cyclo,2'3'-O-isopropylidene uridine C0603010 0 T080234 5',2-O-cyclo,2'3'-O-isopropylidene uridine C007200 cyclopenin 1975 01 01 1984 02 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 Penicillium metabolite; structure 5 EPOXY COMPOUNDS (75-78) D001570 Benzodiazepinones J Org Chem 42(23):3650;1977 Pharmazie 29(8):506;1974 NLM DLJ NLM M0050236 cyclopenin C0056790 4-methyl-3'-phenylspiro(3H-1,4-benzodiazepine- 3,2'-oxirane)-2,5(1H,4H)-dione 20007-87-8 T080239 cyclopenin C007207 cyclotrichosantol 1974 01 01 1982 09 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 isolated from leaves of Trichosantes palmata L., Cucurbitaceae; also characterized as a C(31) 31- nortriterpene; structure 0 CYCLOSTEROIDS (74-82) *D013261 Sterols J Org Chem 38(21):3688;1973 NLM VSR NLM M0050251 cyclotrichosantol C0603017 4 alpha,14 alpha-dimethyl-24-ethyl-9,19-cyclocholest-25-ene-3 beta-ol 41507-26-0 T080254 cyclotrichosantol C414175 nonstructural protein 3, semliki forest virus 2000 10 10 2000 10 11 2000 2000A 2001 2002 amino acid sequence in first source; do not confuse with Nsp3 protein 2 *D016601 RNA-Binding Proteins *D017361 Viral Nonstructural Proteins Nucleic Acids Res 1986 Jul 25;14(14):5667-82 THA THA THA M0370963 nonstructural protein 3, semliki forest virus C0971051 0 T116 Amino Acid, Peptide, or Protein T426259 nonstructural protein 3, semliki forest virus 2000 10 10 T426260 semliki forest virus nonstructural protein 3 2000 10 10 T426261 Nsp3 protein, SFV 2000 10 10 C007213 cytidine diphosphate-4-keto-3,6-dideoxyglucose 1974 01 01 1983 08 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *NUCLEOSIDE DIPHOSPHATE SUGARS (74-78) CDP/analogs (78-78) CYTOSINE NUCLEOTIDES (74-78) DEOXY SUGARS (74-78) *D009702 Nucleoside Diphosphate Sugars J Biol Chem 249(12):3776;1974 NLM DLJ NLM M0050263 cytidine diphosphate-4-keto-3,6-dideoxyglucose C0056905 Cytidine 5'-(trihydrogen diphosphate), mono(3,6-dideoxy-alpha-D-erythro-hexopyranos-4-ulosyl) ester 21870-27-9 T080266 cytidine diphosphate-4-keto-3,6-dideoxyglucose C007264 6-seleno-2'-deoxyguanosine 1974 01 01 2001 02 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *DEOXYTRIBONUCLEOSIDES (74-79) *GUANOSINE (74-79) SELENIUM (74-82) D003849 Deoxyguanosine *Q000031 analogs ; derivatives J Med Chem 17(3):263;1974 NLM TWD TWD M0050344 6-seleno-2'-deoxyguanosine C0603059 37025-79-9 T080347 6-seleno-2'-deoxyguanosine T080346 2'-deoxy-6-selenoguanosine C008290 lipophosphonoglycan 1974 01 01 2001 02 05 1998 1999 2000 2001 2001A 2002 macromolecule accounting for approx 31% of mass of plasma membrane of Acanthamoeba castellanii; consists of neutral sugars, amino sugars, aminophosphonates and long chain fatty acids; present also in Entamoeba histolytica and Leishmania major 198 *LIPOPOLYSACCHARIDES (74-76) FATTY ACIDS (74-76) FATTY ACIDS, UNSATURATED (74-76) PHOSPHOLIPIDS (74-76) *D006028 Glycosphingolipids J Biol Chem 249(11):3335-42;1974 J Biol Chem 251(10):2976;1976 J Cell Biol 62(2):533;1974 NLM TWD TWD M0052013 lipophosphonoglycan C0065051 0 T082016 lipophosphonoglycan T082015 lipophosphoglycan C007224 8-deazafolic acid 1974 01 01 1982 03 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 *FOLIC ACID (74-75) D005492 Folic Acid *Q000031 analogs ; derivatives J Med Chem 17(4):470;1974 NLM RLS NLM M0050281 8-deazafolic acid C0050070 51989-25-4 T080284 8-deazafolic acid C007227 8-deazapteroic acid 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D011622 Pterins J Med Chem 17(4):470;1974 NLM NLM M0050285 8-deazapteroic acid C0603024 51989-24-3 T080288 8-deazapteroic acid C007228 5-deazariboflavin 1974 01 01 1980 04 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 deaza analog of riboflavin used to elucidate chemical role of the flavin coenzyme; structure 14 *RIBOFLAVIN (74-76) D012256 Riboflavin *Q000031 analogs ; derivatives Biochemistry 15(5):1043;1976 Biochemistry 16(6):3586;1977 Biochim Biophys Acta 1980;590(1):97 J Am Chem Soc 96(13):4345;1974 NLM MEG NLM M0050286 5-deazariboflavin C0049133 19342-73-5 T080289 5-deazariboflavin C007233 dehydrocorydalmine 1974 01 01 1981 06 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *QUINOLIZINES (74-81) METHYL ETHERS (74-76) *D000470 Alkaloids J Pharm Sci 63(4):618;1974 NLM NBM NLM M0050293 dehydrocorydalmine C0603026 2007-07-0 T080296 dehydrocorydalmine C007234 9-dehydro-18-dihydroleuconolide-A(3) 1974 01 01 1982 09 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 deriv of leucomycin-A(3); structure 0 *ANTIBIOTICS (74-76) AMINOGLYCOSIDES (74-76) LACTONES (74-76) *D007933 Leucomycins J Antibiot (Tokyo) 27(2):147;1974 NLM VSR NLM M0050294 9-dehydro-18-dihydroleuconolide-A(3) C0603027 52442-94-1 T080297 9-dehydro-18-dihydroleuconolide-A(3) C008305 macrozamin 1975 01 01 2001 02 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from seeds of Encephalartos transvenosus ; E. lanatus; structure 0 *AZO COMPOUNDS (75-76) *METHYLGLYCOSIDES (75-76) D008746 Methylazoxymethanol Acetate *Q000031 analogs ; derivatives J Natural Products 37(4):636;1974 NLM TWD TWD M0052034 macrozamin C0603511 6327-93-1 T082037 macrozamin T082036 methylazoxymethanol-beta-primeveroside C007239 dehydromerodesmosine 1975 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *AMINO ACIDS (75-76) *PYRIDINIUM COMPOUNDS (75-76) D003895 Desmosine *Q000031 analogs ; derivatives Connect Tissue Res 2(3):231;1974 NLM RLS NLM M0050304 dehydromerodesmosine C0603037 5-Undecenedioic acid, 2,10-diamino-5-(((5-amino-5-carboxypentyl)imino)methyl)-, (2S-(2R*,5(R*),10R*))- 51299-87-7 M0050304 M0050303 T080307 dehydromerodesmosine M0050303 5-Undecenedioic acid, 2,10-diamino-5-(((5-amino-5-carboxypentyl)imino)methyl)-, (2S-(2S*,5(S*),10S*))- C0603036 M0050304 M0050303 T080306 5-Undecenedioic acid, 2,10-diamino-5-(((5-amino-5-carboxypentyl)imino)methyl)-, (2S-(2S*,5(S*),10S*))- C007257 2'-deoxyguanosine 5'-phosphate 1969 01 01 2000 12 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd. 113 *GUANINE NUCLEOTIDES (69-78) DEOXYRIBONUCLEOTIDES (69-78) *D003848 Deoxyguanine Nucleotides NLM CCR CCR M0050333 2'-deoxyguanosine 5'-phosphate C0045196 902-04-5 T114 Nucleic Acid, Nucleoside, or Nucleotide 33430-61-4 (di-Na salt) 55056-59-2 (ion(1+)) M0050333 M0309870 M0050333 M0309871 T080336 2'-deoxyguanosine 5'-phosphate T080334 2'-deoxyguanosine 5'-monophosphate T080333 2'-dG-5'-MP T080335 dGMP M0309870 2'-deoxyguanosine 5'-phosphate, disodium salt C0951630 33430-61-4 T114 Nucleic Acid, Nucleoside, or Nucleotide M0050333 M0309870 T339870 2'-deoxyguanosine 5'-phosphate, disodium salt 1999 08 18 M0309871 2'-deoxyguanosine 5'-phosphate, ion (1+) C0951631 55056-59-2 T114 Nucleic Acid, Nucleoside, or Nucleotide M0050333 M0309871 T339871 2'-deoxyguanosine 5'-phosphate, ion (1+) 1999 08 18 C007243 N-demethylcelesticetin 1974 01 01 1979 11 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ANTIBIOTICS (74-75) *CELESTICETIN/analogs (75-79) *THIOGLYCOSIDES (74-75) PYRROLIDINES (74-75) D013862 Thiogalactosides J Antibiotics 26(1):7;1973 NLM SMH NLM M0050310 N-demethylcelesticetin C0603038 D-erythro-alpha-D-galacto-Octopyranoside, 2-((2-hydroxybenzoyl)oxy)ethyl 6,8-dideoxy-7-O-methyl-6-((2-pyrrolidinylcarbonyl)amino)-1-thio-, (S)- 40736-31-0 T080313 N-demethylcelesticetin C007245 N-demethyl-7-O-demethylcelesticetin 1974 01 01 1983 08 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ANTIBIOTICS (74-75) *CELESTICETIN/analogs (75-79) *THIOGLYCOSIDES (74-75) PYRROLIDINES (74-75) D013862 Thiogalactosides J Antibiot 26(1):7;1973 NLM DLJ NLM M0050313 N-demethyl-7-O-demethylcelesticetin C0603041 D-erythro-alpha-D-galacto-Octopyranoside, 2-((2-hydroxybenzoyl)oxy)ethyl 6,8-dideoxy-6-((2-pyrrolidinylcarbonyl)amino)-1-thio-, (S)- 40736-32-1 T080316 N-demethyl-7-O-demethylcelesticetin C007252 L-1-deoxyfluoroglycerol 1974 01 01 1997 07 16 1998 1999 2000 2001 2002 structure 0 *DEOXY SUGARS (81-82) *GLYCERIN (74-75) DEOXY SUGARS (74-81) D005990 Glycerol *Q000031 analogs ; derivatives J Med Chem 17(7):697;1974 NLM ADP BVL M0050325 L-1-deoxyfluoroglycerol C0603051 1,2-Propanediol, 3-fluoro-, 1-(dihydrogen phosphate), (S)-, cpd with cyclohexanamine (1:2) 40147-95-3 T080328 L-1-deoxyfluoroglycerol C059997 Hin recombinase 1989 07 12 2000 12 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from Salmonella typhimurium; mediates site-specific recombination between two inverted repeat sequences(hixL ; hixR) resulting in inversion of the DNA segment between these two sequences 46 *D004254 DNA Nucleotidyltransferases J Biol Chem 1989;264(17):10072 RLS CCR CCR M0166767 Hin recombinase C0062717 EC 2.7.7.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T196772 Hin recombinase C007254 L-1-deoxyfluoroglycerol 3-phosphate 1974 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *DEOXY SUGARS (81-82) *GLYCERIN (74-79) DEOXY SUGARS (74-81) ORGANOPHOSPHORUS CPDS (74-79) *D005994 Glycerophosphates J Med Chem 17(7):697;1974 NLM VSR NLM M0050328 L-1-deoxyfluoroglycerol 3-phosphate C0603052 1,2-Propanediol, 3-fluoro-, 1-(dihydrogen phosphate), (S)- 44925-02-2 T080331 L-1-deoxyfluoroglycerol 3-phosphate C008311 maleamic acid 1969 01 01 2001 02 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 3 AMIDES (69-82) *D008298 Maleates Biol Nauki 1:112;1977 NLM TWD TWD M0052039 maleamic acid C0065569 557-24-4 T082042 maleamic acid T082041 maleic acid monoamide C007259 9-(6-deoxy-alpha-L-mannofuranosyl)adenine 1974 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ADENINE (74-79) *NUCLEOSIDES (74-79) MANNOSE (74-79) D000241 Adenosine *Q000031 analogs ; derivatives J Org Chem 38(21):3704;1973 NLM NLM M0050335 9-(6-deoxy-alpha-L-mannofuranosyl)adenine C0603055 29847-43-6 T080338 9-(6-deoxy-alpha-L-mannofuranosyl)adenine C008330 marthasterone 1974 01 01 2001 02 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 principal aglycone from saponins of starfish, Marthasterias glacialis; structure 1 CHOLESTADIENOLS (74-82) KETOSTEROIDS (74-75) *D013261 Sterols J Chem Soc (Perkin I) 12:1357;1976 J Chem Soc (Perkin I) 16:1745;1973 NLM TWD TWD M0052063 marthasterone C0065728 (3 beta,5 alpha,6 alpha)-3,6- dihydroxy-cholesta-9(11),24-dien-23-one 36564-29-1 T082066 marthasterone T082065 3-beta,6 alpha-dihydroxy-5 alpha-cholesta-9(11),24-dien-23-one C007263 1-(2-deoxy-D-ribofuranosyl)-4-pyridone 1975 01 01 1982 02 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PYRIDONES (75-82) *D003853 Deoxyribonucleosides J Med Chem 17(9):1027;1974 NLM NBM NLM M0050342 1-(2-deoxy-D-ribofuranosyl)-4-pyridone C0603057 0 T080345 1-(2-deoxy-D-ribofuranosyl)-4-pyridone C008338 mebutizide 1974 01 01 2001 02 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 CYCLIC S-OXIDES (74-81) *D013449 Sulfonamides NLM TWD TWD M0052075 mebutizide C0603520 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(1,2-dimethylbutyl)-3,4-dihydro-, 1,1-dioxide 3568-00-1 T082078 mebutizide T082077 6-chloro-3-(1,2-dimethylbutyl)-2H-1,2,4- benzothiadiazine-7-sulfonamide-1,1-dioxide C008344 alpha-melanotropin hydrazide 1975 01 01 2001 02 05 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 0 HYDRAZINES (75-81) MSH/*analogs (75-87) D000521 alpha-MSH *Q000031 analogs ; derivatives Int J Pept Protein Res 6(5):303;1974 NLM TWD TWD M0052086 alpha-melanotropin hydrazide C0603522 alpha-Melanotropin, 13-L-valine-, 13-hydrazide 55325-41-2 T082089 alpha-melanotropin hydrazide T082088 MSH hydrazide C007275 descarboxylysergic acid 1974 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ERGOLINES (74-75) D008237 Lysergic Acid *Q000031 analogs ; derivatives J Med Chem 17(3):312;1974 NLM RLS NLM M0050364 descarboxylysergic acid C0603064 9,10-didehydro-6-methylergoline 51867-17-5 T080367 descarboxylysergic acid C007279 3-desmethylcolchicine 1974 01 01 1977 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *COLCHICINE (74-77) D003078 Colchicine *Q000031 analogs ; derivatives J Natural Prod 36(3):338;1973 NLM NLM M0050372 3-desmethylcolchicine C0603065 7336-33-6 T080375 3-desmethylcolchicine C007282 desmethylmedazepam 1975 01 01 1998 11 06 1999 2000 2001 2002 structure 0 *D001568 Anti-Anxiety Agents, Benzodiazepine D008472 Medazepam *Q000031 analogs ; derivatives J Chromatogr 100(1):49;1974 NLM BQV TPW M0050376 desmethylmedazepam C0603069 1694-78-6 M0050376 M0050375 T080379 desmethylmedazepam M0050375 Ro 5-2925 C0603068 M0050376 M0050375 T080378 Ro 5-2925 C007283 4-desoxyisopyridoxal 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 analog of pyridoxal; structure 0 *PYRIDOXAL (74-75) D011730 Pyridoxal *Q000031 analogs ; derivatives J Med Chem 14(7):568;1971 NLM NLM M0050377 4-desoxyisopyridoxal C0603070 32453-97-7 T080380 4-desoxyisopyridoxal C007295 4,4'-diaminodicyclohexylmethane carbonate 1974 01 01 1994 05 26 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 AMINES (74-82) *D003510 Cyclohexanes Gig Sanit 38(11):31;1973 NLM MLH NLM M0050405 4,4'-diaminodicyclohexylmethane carbonate C0603072 37872-62-1 T080408 4,4'-diaminodicyclohexylmethane carbonate C007298 4,5-diaminohypoxanthine 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D007042 Hypoxanthines J Pharm Sci 63(4):622;1974 NLM NLM M0050412 4,5-diaminohypoxanthine C0603073 4,5-diamino-6-hydroxypyrimidine 1672-50-0 T080415 4,5-diaminohypoxanthine C007299 2,3-diaminoisocarbostyril 3,4 dihydro 1974 01 01 1982 09 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 DIAMINES (74-82) *D007546 Isoquinolines J Pharm Soc Jap 93(12):1581;1973 NLM VSR NLM M0050413 2,3-diaminoisocarbostyril 3,4 dihydro C0603074 0 T080416 2,3-diaminoisocarbostyril 3,4 dihydro C007302 4,5-diamino-2-thiouracil 1974 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *THIOURACIL (74-75) DIAMINES (74-82) D013889 Thiouracil *Q000031 analogs ; derivatives J Pharm Sci 63(4):622;1974 NLM VSR NLM M0050417 4,5-diamino-2-thiouracil C0603076 4,5-diamino-6-hydroxy-2-thiopyrimidine 1004-76-8 T080420 4,5-diamino-2-thiouracil C007309 4-diazo-3,5-dimethylpyrazole 1974 01 01 1982 02 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 AZO CPDS (74-79) DIAZONIUM COMPOUNDS (79-82) *D011720 Pyrazoles J Pharm Soc Jpn 94(1):17;1974 NLM NBM NLM M0050431 4-diazo-3,5-dimethylpyrazole C0048238 4H-Pyrazole, 4-diazo-3,5-dimethyl- 51463-90-2 T080434 4-diazo-3,5-dimethylpyrazole C007348 N-(2,6-dichlorophenyl)anthranilic acid 1974 01 01 2001 02 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 0 CHLOROBENZENES (74-82) *D000879 Anthranilic Acids Folia Pharmacol Jap 69(2):257;1973 NLM TWD TWD M0050490 N-(2,6-dichlorophenyl)anthranilic acid C0067448 13625-57-5 54850-12-3 (mono-Na salt) M0050490 M0309920 T080493 N-(2,6-dichlorophenyl)anthranilic acid M0309920 N-(2,6-dichlorophenyl)anthranilic acid, monosodium salt C0951660 54850-12-3 M0050490 M0309920 T339920 N-(2,6-dichlorophenyl)anthranilic acid, monosodium salt 1999 08 18 C007312 3-diazoquinoline tetrafluoroborate 1974 01 01 1998 02 09 1998 1999 2000 2001 2002 reagent for specific modification of lysyl residues 0 AZO CPDS (74-79) DIAZONIUM COMPOUNDS (74-82) *D011804 Quinolines NLM BQV NLM M0050435 3-diazoquinoline tetrafluoroborate C0603079 3-Quinolinediazonium, tetrafluoroborate(1-) 398-41-4 T080438 3-diazoquinoline tetrafluoroborate C007315 dibenzothioazocines 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D001392 Azocines J Pharm Soc Jpn 93(8):991;1973 J Pharm Soc Jpn 97(1):24-31;1977 NLM NLM M0050438 dibenzothioazocines C0057780 0 T080441 dibenzothioazocines C412102 (4,5-bis(aminomethyl)-2,2-dimethyl-1,3-dioxolane-N,N')-(malonato-O,O')platinum(II) 2000 08 17 2000 08 17 2000 2000A 2001 2002 structure in first source 1 *D009944 Organoplatinum Compounds Acta Crystallogr C 2000 Jun;56 ( Pt 6):653-4 SZM SZM SZM M0368130 (4,5-bis(aminomethyl)-2,2-dimethyl-1,3-dioxolane-N,N')-(malonato-O,O')platinum(II) C0916527 0 T109 Organic Chemical M0368130 M0368132 M0368130 M0368131 T421967 (4,5-bis(aminomethyl)-2,2-dimethyl-1,3-dioxolane-N,N')-(malonato-O,O')platinum(II) 2000 08 17 M0368132 B(AMe)-D-D-M-platinum(II) C0917693 M0368130 M0368132 T421969 B(AMe)-D-D-M-platinum(II) 2000 08 17 M0368131 cis-((4R,5R)-4,5-bis(aminomethyl)-2,2-dimethyl-1,3-dioxolane-N,N')-(malonato-O,O')platinum(II) C0916528 M0368130 M0368131 T421968 cis-((4R,5R)-4,5-bis(aminomethyl)-2,2-dimethyl-1,3-dioxolane-N,N')-(malonato-O,O')platinum(II) 2000 08 17 C007319 1,1-dibromoethylene 1975 01 01 1982 02 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ETHYLENES (75-82) *D006842 Hydrocarbons, Brominated Arch Environ Health 30(1):26;1975 NLM NBM NLM M0050446 1,1-dibromoethylene C0603080 593-92-0 T080449 1,1-dibromoethylene C007320 2,2-dibromo-3-nitrilopropionamide 1974 01 01 1980 12 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 ACETAMIDES (74-81) *D009570 Nitriles J Agr Food Chem 21(5):838;1973 NLM RLS NLM M0050447 2,2-dibromo-3-nitrilopropionamide C0045292 2,2-dibromo-2-cyanoacetamide 10222-01-2 T080450 2,2-dibromo-3-nitrilopropionamide C044144 T7 protocol 1985 02 25 2001 02 05 1996 1997 1998 1999 2000 2001 2001A 2002 chemotherapy protocol consisting of above 7 cpds; used in treatment of osteosarcoma 6 *D000971 Antineoplastic Combined Chemotherapy Protocols D001761 Bleomycin D002955 Leucovorin D003520 Cyclophosphamide D003609 Dactinomycin D004317 Doxorubicin D008727 Methotrexate D014750 Vincristine Ann Pediatr (Paris) 1984;31(9):773 MEG CCR CCR M0129133 T7 protocol C0208119 0 M0129133 M0129131 T159138 T7 protocol M0129131 T-10 protocol C0284955 M0129133 M0129131 T159136 T-10 protocol T159137 T10 protocol C016180 argipressin, Val(4)- 1978 01 01 2000 08 17 1998 1999 2000 2000A 2001 2002 RN given refers to (L-Val-D-Arg)-isomer 12 D001127 Argipressin *Q000031 analogs ; derivatives J Med Chem 20(9):1173;1977 NLM CCR CCR M0065999 argipressin, Val(4)- C0078107 52049-52-2 T116 Amino Acid, Peptide, or Protein 51980-15-5 ((L-Val-L-Arg)-isomer) M0065999 M0313113 T096002 argipressin, Val(4)- T095998 4-Val-argipressin T096000 arginine vasopressin, Val(4)- T096001 argipressin, valine(4)- T095999 VDAVP M0313113 argipressin, Val(4)-, (L-Val-L-Arg)-isomer C0889863 51980-15-5 T116 Amino Acid, Peptide, or Protein M0065999 M0313113 T343113 argipressin, Val(4)-, (L-Val-L-Arg)-isomer 1999 08 18 C008693 obtusifoliol 1974 01 01 2001 02 05 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 10 *D002775 Cholestadienols D010840 Phytosterols Can J Microbiol 23(6):751;1977 J Biol Chem 249(13):4267;1974 NLM TWD TWD M0052759 obtusifoliol C0069296 16910-32-0 T082762 obtusifoliol T082761 4alpha,14alpha-dimethyl-5alpha-ergosta-8,24(28)-dien-3beta-ol C008701 oleandrigenin 1974 01 01 2001 02 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to (3beta)-isomer; structure 6 *CARDANOLIDES (74-77) HYDROXYSTEROIDS (74-77) *D002298 Cardenolides Helv Chim Acta 56(1):2782;1973 NLM TWD TWD M0052772 oleandrigenin C0525149 465-15-6 T082775 oleandrigenin T082774 3 alpha,14-dihydroxy-16 beta-acetoxy-5 beta,14 beta- card-20(22)-enolide C007328 N(6)-2'-O-dibutyryl-8-thiocyclic AMP 1974 01 01 1993 08 19 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *CYCL AMP (74-75) BUTYRATES (74-75) SULFIDES (74-75) THIONUCLEOTIDES (74-82) D003994 Bucladesine *Q000031 analogs ; derivatives C R Acad Sci Paris 277(19):2057;1973 NLM TPW TPW M0050462 N(6)-2'-O-dibutyryl-8-thiocyclic AMP C0376799 34409-10-4 T080465 N(6)-2'-O-dibutyryl-8-thiocyclic AMP C008706 oosporein 1974 01 01 2001 02 05 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from Chaetomium trilaterale; found in moldy peanuts 8 *QUINONES (74-90) *D016227 Benzoquinones D009183 Mycotoxins J Agric Food Chem 22(3):517;1974 NLM TWD TWD M0052795 oosporein C0069555 2,2',5,5'-tetrahydroxy-4,4'-dimethyl(bi-1,4-cyclohexadien-1-yl)-3,3',6,6'-tetrone 475-54-7 T082798 oosporein Merck Index, 9th ed, p. 890, #6689 T082797 3,3',6,6'-tetrahydroxy-5,5'-dimethyl-2,2'-bi-p- benzoquinone C007337 1,3-dichloro-2-butene 1974 01 01 1982 02 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 ALKENES (74-82) *D006843 Hydrocarbons, Chlorinated Environ Health Perspect 21:269;1977 Gig Tr Prof Zabol 18(6):51;1974 NLM NBM NLM M0050482 1,3-dichloro-2-butene C0043919 926-57-8 T080485 1,3-dichloro-2-butene C007338 2,8-dichlorodibenzofuran 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CHLORINE (74-75) *D001572 Benzofurans Environ Health Perspec 5(0):267;1974 NLM NLM M0050483 2,8-dichlorodibenzofuran C0603086 5409-83-6 T080486 2,8-dichlorodibenzofuran C044922 MACOP-B protocol 1985 05 09 2001 02 05 1996 1997 1998 1999 2000 2001 2001A 2002 chemotherapy protocol consisting of above cpds; used in treatment of large cell and immunoblastic lymphomas 131 *D000971 Antineoplastic Combined Chemotherapy Protocols D001761 Bleomycin D002955 Leucovorin D003520 Cyclophosphamide D004317 Doxorubicin D008727 Methotrexate D011241 Prednisone D014750 Vincristine Ann Intern Med 1985;102(5):596 MEG CCR CCR M0130915 MACOP-B protocol C0065476 0 M0130915 M0130914 T160920 MACOP-B protocol T160918 MECOP-B PROTOCOL M0130914 TTL-I protocol C0164275 M0130915 M0130914 T160919 TTL-I protocol C007344 2,6-dichloromercuri-4-nitrophenol 1974 01 01 1982 08 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *MERCURY (74-77) *ORGANOMETALLIC COMPOUNDS (74-77) NITROPHENOLS (74-77) *D002730 Chloromercurinitrophenols D013439 Sulfhydryl Reagents Arch Int Physiol Biochem 81(2):366;1973 NLM CHA NLM M0050487 2,6-dichloromercuri-4-nitrophenol C0603088 24579-93-9 T080490 2,6-dichloromercuri-4-nitrophenol C007345 2,5-dichloro-4-methoxyphenol 1974 01 01 1977 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PHENOLS (74-77) CHLOROBENZENES (74-77) *D002733 Chlorophenols J Agric Food Chem 19(4):750;1971 NLM NLM M0050488 2,5-dichloro-4-methoxyphenol C0603089 18113-14-9 T080491 2,5-dichloro-4-methoxyphenol C008728 oxamide 1974 01 01 2001 02 05 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 induces hydronephrosis in rat kidneys; structure 10 *OXALATES (74-75) AMIDES (74-75) D010072 Oxamic Acid *Q000031 analogs ; derivatives Infect Immun 9(4):766;1974 NLM TWD TWD M0052825 oxamide C0069729 471-46-5 T082828 oxamide Merck Index, 8th ed, p. 772 T082827 oxalic acid diamide C007349 1-(3,4-dichlorophenyl)-3-(4-((1-ethyl-3-piperidyl)amino)-6-methyl-2-pyrimidinyl)guanidine 1974 01 01 1982 09 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CHLOROBENZENES (74-82) PIPERIDINES (74-82) PYRIMIDINES (74-82) *D006146 Guanidines J Med Chem 17(1):75;1974 NLM VSR NLM M0050491 1-(3,4-dichlorophenyl)-3-(4-((1-ethyl-3-piperidyl)amino)-6-methyl-2-pyrimidinyl)guanidine C0603091 21062-28-2 T080494 1-(3,4-dichlorophenyl)-3-(4-((1-ethyl-3-piperidyl)amino)-6-methyl-2-pyrimidinyl)guanidine C007351 3,5-dichlorosalicylanilide 1975 01 01 1998 11 09 1999 2000 2001 2002 0 *SALICYLAMIDES (75-77) CHLORINE (75-77) *D012458 Salicylanilides FEBS Letters 49(3):338;1975 NLM BQV NLM M0050499 3,5-dichlorosalicylanilide C0603092 4214-48-6 T080502 3,5-dichlorosalicylanilide C412103 trichodion 2000 08 17 2000 2001 2002 structure in first source 2 *D011753 Pyrones FEBS Lett 2000 Jul 21;477(3):219-23 BMB BMB M0368134 trichodion C0916529 0 T109 Organic Chemical T421971 trichodion 2000 08 17 C007354 S-(1,2-dichlorovinyl)-3-mercaptopropionic acid 1974 01 01 1992 06 29 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2-ketoacid dehydrogenase antagonist 4 *SULFHYDRYL COMPOUNDS (74-82) PROPIONATES (74-79) VINYL COMPOUNDS (74-79) *D011426 Propionic Acids Biochem Pharm 20(9):2417;1973 NLM TPW NLM M0050505 S-(1,2-dichlorovinyl)-3-mercaptopropionic acid C0162974 2148-04-1 M0050505 M0050503 M0050505 M0050504 T080508 S-(1,2-dichlorovinyl)-3-mercaptopropionic acid M0050503 5,6-DCTH C0097835 M0050505 M0050503 T080506 5,6-DCTH M0050504 5,6-dichloro-4-thia-5-hexenoate C0097843 M0050505 M0050504 T080507 5,6-dichloro-4-thia-5-hexenoate C412104 major outer membrane protein, Thiobacillus 2000 08 17 2000 2001 2002 the major outer membrane protein from the acidophilic bacterium Thiobacillus ferrooxidans; amino acid sequence in first source 2 *D001425 Bacterial Outer Membrane Proteins Appl Environ Microbiol 2000 Jun;66(6):2318-24 BMB BMB M0368135 major outer membrane protein, Thiobacillus C0916530 0 T116 Amino Acid, Peptide, or Protein T421972 major outer membrane protein, Thiobacillus 2000 08 17 T421973 omp-40 gene product 2000 08 17 T421974 outer membrane protein, 40-kDa 2000 08 17 C007356 dicloeta 1974 01 01 1994 02 16 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *HETACILLIN (74-84) DRUG COMBINATIONS (74-88) D004009 Dicloxacillin D010406 Penicillins Minerva Med 64(82):4319;1973 NLM PML NLM M0050508 dicloeta C0057876 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, (2S-(2alpha,5alpha,6beta))-, mixt. with (2S-(2alpha,5alpha,6beta(S*)))-6-(2,2-dimethyl-5-oxo-4-phenyl-1-imidazolidinyl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid 76391-76-9 T080511 dicloeta C007360 1,3-dicyclohexyl-5,5-diallylbarbituric acid 1974 01 01 1994 07 28 1995 1996 1997 1998 1999 2000 2001 2002 0 *BARBITURATES (74-76) ALLOBARBITAL/*analogs (77-94) ALLYL COMPOUNDS (74-76) CYCLOHEXANES (74-82) *D001463 Barbiturates Pol J Pharmacol Pharm 25(4):379;1973 NLM MLH TPW M0050512 1,3-dicyclohexyl-5,5-diallylbarbituric acid C0603093 34374-12-4 T080515 1,3-dicyclohexyl-5,5-diallylbarbituric acid C033890 phenoxyacetone 1982 04 29 2000 08 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 1 D000096 Acetone *Q000031 analogs ; derivatives Biochem Biophys Res Commun 1982;104(2):597 MEG TWD TWD M0104851 phenoxyacetone C0615916 621-87-4 T109 Organic Chemical T134855 phenoxyacetone C007364 didodecylphthalate 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 FATTY ALCOHOLS (74-75) *D010795 Phthalic Acids Gig Tr Prof Zabol 17(11):51;1973 NLM NLM M0050515 didodecylphthalate C0603095 2432-90-8 T080518 didodecylphthalate C035293 1-hydroxy-1-phenyl-2-propanone 1982 08 20 2000 08 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 8 D000096 Acetone *Q000031 analogs ; derivatives Folia Microbiol (Praha) 1982;27(3):173 CHA TWD TWD M0108264 1-hydroxy-1-phenyl-2-propanone C0377548 90-63-1 T109 Organic Chemical T123 Biologically Active Substance T138268 1-hydroxy-1-phenyl-2-propanone T138266 1-hydroxy-1-phenylacetone T138267 phenylacetylcarbinol C007371 6-((3-(N,N-diethylamino)methyl-4-hydroxy)anilino)-5,8-dimethoxy-2,4-dimethylquinoline 1975 01 01 1982 02 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 analog of amodiaquine; structure 0 ANILINE COMPOUNDS (75-82) DIETHYLAMINES (75-79) *D011804 Quinolines J Med Chem 17(9):972;1974 NLM NBM NLM M0050534 6-((3-(N,N-diethylamino)methyl-4-hydroxy)anilino)-5,8-dimethoxy-2,4-dimethylquinoline C0603098 0 T080537 6-((3-(N,N-diethylamino)methyl-4-hydroxy)anilino)-5,8-dimethoxy-2,4-dimethylquinoline C008734 oxogestone phenylpropionate 1975 01 01 2001 02 05 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 1 HYDROXYSTEROIDS (75-76) KETOSTEROIDS (75-76) PHENYLPROPIONATES (75-80) *D009652 Norpregnenes D011373 Progestational Hormones, Synthetic Acta Eur Fertil 3(1):37;1972 NLM TWD TWD M0052839 oxogestone phenylpropionate C0069784 19-Norpregn-4-en-3-one, 20-(1-oxo-3-phenylpropoxy)-, (20R)- 16915-80-3 T082842 oxogestone phenylpropionate Negwer #4665 UD 20:25j T082841 20 beta-hydroxy-19-norpregn-4-en-3-one 20-(beta- phenyl)propionate C007376 5,5-diethyl-2-ethoxytetrahydro-4,6-pyrimidinedione 1975 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ETHOXY COMPOUNDS (75-76) *D011744 Pyrimidinones J Pharm Sci 63(10):1633;1974 NLM NLM M0050538 5,5-diethyl-2-ethoxytetrahydro-4,6-pyrimidinedione C0603101 0 T080541 5,5-diethyl-2-ethoxytetrahydro-4,6-pyrimidinedione C007380 diethyl S-n-propyl phosphorothiolate 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D009946 Organothiophosphorus Compounds Biochem Pharmacol 23(3):751;1974 NLM NLM M0050545 diethyl S-n-propyl phosphorothiolate C0603102 20195-06-6 T080548 diethyl S-n-propyl phosphorothiolate C007383 difebarbamate 1969 01 01 1982 07 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 CARBAMATES (69-82) ETHERS (74-78) *D001463 Barbiturates Praxis 67(22):839;1978 NLM CHA NLM M0050546 difebarbamate C0057977 1,3-bis(3-butoxy-2-hydroxypropyl)-5-ethyl-5-phenylbarbituric acid dicarbamate 15687-09-9 T080549 difebarbamate C007398 dihydrocorynantheol 1974 01 01 1981 06 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 alkaloid from Mitragyna species; isomer of corynantheidol; 0 INDOLES (74-81) *D000470 Alkaloids Planta Med (24(1):13;1973 NLM NBM NLM M0050579 dihydrocorynantheol C0603109 Corynan-17-ol 2270-72-6 T080582 dihydrocorynantheol C007400 3,12-dihydro-6,11-dihydroxy-3,3,12-trimethyl-5-(3- methylbut-2-enyl)pyrano(3,2-c)acrid-7-one 1974 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 analog of acronycine from wood of Atlantia ceylanica; structure 0 *ACRIDINES (74-75) *ALKALOIDS (74-75) D000175 Acronine *Q000031 analogs ; derivatives NLM RLS NLM M0050584 3,12-dihydro-6,11-dihydroxy-3,3,12-trimethyl-5-(3- methylbut-2-enyl)pyrano(3,2-c)acrid-7-one C0603110 0 T080587 3,12-dihydro-6,11-dihydroxy-3,3,12-trimethyl-5-(3- methylbut-2-enyl)pyrano(3,2-c)acrid-7-one C007401 11-hydroxynoracronycine 1974 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 analog of acronycine from wood of Atalantia ceylanica; structure 0 *ALKALOIDS (74-75) ACRIDINES (74-75) D000175 Acronine *Q000031 analogs ; derivatives Lloydia 39(6):399;1976 NLM RLS NLM M0050585 11-hydroxynoracronycine C0044751 3,12-dihydro-6,11-dihydroxy-3,312-trimethyl-7H- pyrano(2,3-c)acridin-7-one 27067-70-5 T080588 11-hydroxynoracronycine C007410 dihydromarthasterone 1974 01 01 2001 02 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 principal aglycone from saponins of starfish, Marthasterias glacialis; structure 1 *STEROLS (74-87) HYDROXYSTEROIDS (74-75) KETOSTEROIDS (74-75) *D002783 Cholestenones D012502 Sapogenins J Chem Soc (Perkin I) 16:1745;1973 NLM TWD TWD M0050595 dihydromarthasterone C0603119 Cholest-9(11)-en-23-one, 3,6-dihydroxy-, (3beta,5alpha,6alpha)- 34218-94-5 T080598 dihydromarthasterone T080597 3 beta,6 alpha-dihydroxy-5 alpha-cholest-9(11)-en- 23-one C007406 3,4-dihydro-2H-imidazo(1,2-c)quinazoline 1975 01 01 1982 02 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 IMIDAZOLES (75-82) *D011799 Quinazolines J Pharm Soc Jap 94(4):417;1974 NLM NBM NLM M0050589 3,4-dihydro-2H-imidazo(1,2-c)quinazoline C0603114 0 T080592 3,4-dihydro-2H-imidazo(1,2-c)quinazoline C066716 HiC-COM protocol 1991 02 05 2001 02 05 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 chemotherapy protocol consisting of the above cpds; used in treatment of stage III ; IV Burkitt's lymphoma ; B-cell acute lymphoblastic leukemia 3 *D000971 Antineoplastic Combined Chemotherapy Protocols D003520 Cyclophosphamide D003561 Cytarabine D008727 Methotrexate D014750 Vincristine J Clin Oncol 1991;9(1):133 TPW CCR CCR M0183053 HiC-COM protocol C0082890 0 T213058 HiC-COM protocol T213056 COMA protocol T213057 HiCCOM C071110 FMC protocol 1991 10 29 2001 02 05 1995 1996 1997 1998 1999 2000 2001 2001A 2002 chemotherapy protocol consisting of the above cpds; used in treatment of metastatic breast carcinoma 12 *D000971 Antineoplastic Combined Chemotherapy Protocols D003520 Cyclophosphamide D005472 Fluorouracil D008942 Mitoxantrone Cancer Invest 1991;9(3):249 TPW CCR CCR M0193310 FMC protocol C0118004 0 T223315 FMC protocol T223313 CNF protocol T223314 FNC C007411 3,4-dihydro-8-methoxybenzo(c)phenanthridin-1(2H)-one 1974 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 METHYL ETHERS (74-79) *D010617 Phenanthridines J Chem Soc (perkin I):1158;1973 NLM NLM M0050596 3,4-dihydro-8-methoxybenzo(c)phenanthridin-1(2H)-one C0603120 0 T080599 3,4-dihydro-8-methoxybenzo(c)phenanthridin-1(2H)-one C007413 2,2-dihydroperoxy-2,2-dibutylperoxide 1974 01 01 1982 08 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D010545 Peroxides D013439 Sulfhydryl Reagents Pfleugers Arch 3 4(1):51;1973 NLM CHA NLM M0050597 2,2-dihydroperoxy-2,2-dibutylperoxide C0603121 Hydroperoxide, (dioxybis(1-methylpropylidene))bis- 126-76-1 T080600 2,2-dihydroperoxy-2,2-dibutylperoxide C108123 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine 1997 09 29 2001 02 05 1999 2000 2001 2001A 2002 64 *D011720 Pyrazoles *D011743 Pyrimidines D019061 src-Family Kinases Q000037 antagonists ; inhibitors D000970 Antineoplastic Agents J Biol Chem 1996 Jan 12;271(2):695-701 BMB BMB BMB M0281006 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine C0665709 0 D004791 Enzyme Inhibitors M0281006 M0281003 M0281006 M0281004 M0281006 M0281005 T311011 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine M0281003 CP118,556 C0754645 M0281006 M0281003 T311008 CP118,556 M0281004 PP1 Src tyrosine kinase inhibitor C0754646 M0281006 M0281004 T311009 PP1 Src tyrosine kinase inhibitor M0281005 tyrosine kinase inhibitor PP1 C0665708 M0281006 M0281005 T311010 tyrosine kinase inhibitor PP1 C007419 dihydrouracil 1974 01 01 1980 05 21 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 40 *URACIL (74-75) D014498 Uracil *Q000031 analogs ; derivatives Biochemistry 13(2):369;1974 J Bacteriol 1980;141(3):1291 Radiat Res 75(2):252;1978 NLM MEG NLM M0050602 dihydrouracil C0058124 504-07-4 T080605 dihydrouracil C076190 BACOD protocol 1992 09 18 2001 02 05 1996 1997 1998 1999 2000 2001 2001A 2002 used for treatment of non Hodgkin's lymphoma; chemotherapy protocol consisting of above cpds 9 *D000971 Antineoplastic Combined Chemotherapy Protocols D001761 Bleomycin D003520 Cyclophosphamide D003907 Dexamethasone D004317 Doxorubicin D014750 Vincristine J Neurooncol 1991 Dec;11(3):255-7 RLS CCR CCR M0204987 BACOD protocol C0171337 0 T234992 BACOD protocol T234990 CHOD-B protocol T234991 CHOD-Bleo protocol C007425 1 alpha,25-dihydroxycholesterol 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CHOLESTEROL (74-76) HYDROXYSTEROIDS (74-76) *D006888 Hydroxycholesterols Helv Chim Acta 57(3):781;1974 NLM NLM M0050617 1 alpha,25-dihydroxycholesterol C0603125 Cholest-5-ene-1,3,25-triol, (1alpha,3beta)- 50392-32-0 T080620 1 alpha,25-dihydroxycholesterol C417205 sheath degrading enzyme 2000 12 25 2001 2002 an enzyme with either hydrolytic or polysaccharide eliminase activity that catalyzes the degradation of Sphaerotilus natans sheath 1 *D004798 Enzymes Appl Environ Microbiol 2000 Nov;66(11):4998-5004 THA THA M0375113 sheath degrading enzyme C0962697 0 T116 Amino Acid, Peptide, or Protein T121 Pharmacologic Substance T431647 sheath degrading enzyme 2000 12 25 C080072 MiCaT protocol 1993 04 06 2001 02 05 1998 1999 2000 2001 2001A 2001B 2002 chemotherapy regimen consisting of above cpds; used in the therapy of breast cancer 4 *D000971 Antineoplastic Combined Chemotherapy Protocols D003520 Cyclophosphamide D008942 Mitoxantrone D013852 Thiotepa Anticancer Res 1992 Nov-Dec;12(6B):2243-4 RLS CCR CCR M0214087 MiCaT protocol C0657724 0 T244092 MiCaT protocol T244091 MCT protocol T432793 CTM protocol 2001 01 10 C007428 5,5'-dihydroxylysylnorleucine 1974 01 01 2000 12 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 44 HYDROXYLYSINE/analogs (76-82) LYSINE (74-75) NORLEUCINE (74-76) NORLEUCINE/analogs (76-82) *D004151 Dipeptides Arch Biochem Biophys 158(1):106;1973 Biochem J 145(1):119;1975 Biochem J 149(2):381;1975 C R Acad Sci D (Paris) 281(19):1447;1975 Connect Tissue Res 2(3):223;1974 Exp Aging Res 3(2):87;1977 J Invest Dermatol 68(3):146;1977 Kidney (Suppl 2):S-97;1975 Naunyn Schmiedebergs Arch Pharmacol 301:241;1978 NLM CCR CCR M0050627 5,5'-dihydroxylysylnorleucine C0048879 12764-49-7 T116 Amino Acid, Peptide, or Protein T130 Indicator, Reagent, or Diagnostic Aid T080630 5,5'-dihydroxylysylnorleucine T080626 5,5'-dihydroxy-Lys-Nle T080627 5,5'-dihydroxylysinonorleucine T080628 DHLNL T080629 delta,delta'-dihydroxylysylnonorleucine C008884 6-phosphogluconate 1974 01 01 2001 02 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 86 *SUGAR PHOSPHATES (74-82) ORGANOPHOSPHORUS COMPOUNDS (74-75) *D005942 Gluconates Anesthesiology 40(3):261;1974 Biochem J 173(2):467;1978 Biol Neonate 1980;37(1-2):15 Eur J Biochem 54:195;1975 NLM TWD TWD M0053124 6-phosphogluconate C0049701 921-62-0 T083127 6-phosphogluconate T083126 gluconate 6-phosphate C007435 3,4-dihydroxypyridine 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 3 *D011725 Pyridines J Formosan Med Assoc 73(9):73;1974 NLM NLM M0050640 3,4-dihydroxypyridine C0046987 3,4-pyridinediol 10182-48-6 T080643 3,4-dihydroxypyridine C007439 di(inositolphosphoryl)ceramide 1974 01 01 1982 09 22 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 novel sphingolipid from Nenrospora crassa 0 *CEREBROSIDES (74-79) PHOSPHOINOSITIDES (74-82) *D006028 Glycosphingolipids J Biol Chem 249(11):3388;1974 NLM VSR NLM M0050641 di(inositolphosphoryl)ceramide C0603127 0 T080644 di(inositolphosphoryl)ceramide C097603 LNH 87 protocol 1996 02 12 2001 02 05 1997 1998 1999 2000 2001 2001A 2002 chemotherapy protocol consisting of above compounds for treatment of aggressive non-Hodgkin's lymphoma; ACVBP is induction phase of LNH87 16 *D000971 Antineoplastic Combined Chemotherapy Protocols D001761 Bleomycin D003520 Cyclophosphamide D004317 Doxorubicin D011241 Prednisone D014751 Vindesine Blood 1996 Jan 1;87(1):265-72 THA CCR CCR M0256552 LNH 87 protocol C0385708 0 M0256552 M0256550 T286557 LNH 87 protocol T286556 LNH87 protocol M0256550 ACVBP protocol C0385706 M0256552 M0256550 T286555 ACVBP protocol C417208 CV 1013 2000 12 25 2001 2002 a pancaspase inhibitor; no further information available 12/00 1 *D004791 Enzyme Inhibitors D020169 Caspases Q000037 antagonists ; inhibitors Toxicol Appl Pharmacol 2000 Nov 15;169(1):77-83 THA THA M0375117 CV 1013 C0962701 0 T109 Organic Chemical T121 Pharmacologic Substance T431652 CV 1013 2000 12 25 T431653 CV-1013 2000 12 25 T431654 CV1013 2000 12 25 C007455 4-dimethylaminobibenzyl 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 DIMETHYLAMINES (74-75) *D001632 Bibenzyls Xenobiotica 1(4/5):323;1971 NLM NLM M0050670 4-dimethylaminobibenzyl C0048247 14301-09-8 T080673 4-dimethylaminobibenzyl C007458 3-(2-dimethylaminoethyl)benzo(b)thiophene 1974 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ETHYLAMINES (74-82) *D013876 Thiophenes Drug Metab Disp 2(3):228;1974 NLM VSR NLM M0050671 3-(2-dimethylaminoethyl)benzo(b)thiophene C0603141 0 T080674 3-(2-dimethylaminoethyl)benzo(b)thiophene C007459 beta-dimethylaminoethyl-alpha,alpha-diphenyl-alpha- propargoxyacetate 1974 01 01 1982 09 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ALKYNES (74-82) *D004158 Diphenylacetic Acids Clin Terap 52(4):343;1970 NLM VSR NLM M0050672 beta-dimethylaminoethyl-alpha,alpha-diphenyl-alpha- propargoxyacetate C0603142 2765-97-1 T080675 beta-dimethylaminoethyl-alpha,alpha-diphenyl-alpha- propargoxyacetate C007460 2-dimethylaminoethyl phosphate 1974 01 01 1982 10 04 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *DIMETHYLAMINES (74-82) *D009943 Organophosphorus Compounds Nature 247(235):55;1974 NLM VSR NLM M0050673 2-dimethylaminoethyl phosphate C0603143 6909-62-2 T080676 2-dimethylaminoethyl phosphate C007461 dimethylaminomethylene methyl esters 1975 01 01 1987 08 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 IMINES (75-82) *D004123 Dimethylamines Biomed Mass Spec 1(2):115;1974 NLM DLV NLM M0050674 dimethylaminomethylene methyl esters C0603144 0 T080677 dimethylaminomethylene methyl esters C417209 thiacloprid 2000 12 25 2001 2002 structure in first source 2 *D011725 Pyridines *D013843 Thiazines Toxicol Appl Pharmacol 2000 Nov 15;169(1):114-20 THA THA M0375118 thiacloprid C0962702 0 T109 Organic Chemical T121 Pharmacologic Substance T431655 thiacloprid 2000 12 25 C007467 4-dimethylamino-3,5-xylenol 1975 01 01 1982 02 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 hydrolysis product of Zectran; structure 0 AMINOPHENOLS (79-82) DIMETHYLAMINES (75-79) *D014992 Xylenes Bull Environ Contam Toxicol 12(5):599;1974 NLM NBM NLM M0050686 4-dimethylamino-3,5-xylenol C0603152 6120-10-1 T080689 4-dimethylamino-3,5-xylenol C417210 p190-A protein 2000 12 26 2001 2002 amino acid sequence in first source; GenBank AF159851 1 *D020703 ras GTPase-Activating Proteins D016147 Genes, Tumor Suppressor Gene 2000 Oct 17;257(1):23-31 THA THA M0375119 p190-A protein C0962703 0 T116 Amino Acid, Peptide, or Protein T431656 p190-A protein 2000 12 26 T431657 p190-A gene product 2000 12 26 C007580 edogestrone 1974 01 01 2001 08 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 0 *PREGNENES (74-75) *PROGESTATIONAL HORMONES (74-75) ACETALS (74-82) ANDROGENS/*antag (74-78) DIOXOLES (74-75) *D011282 Pregnenediones D011373 Progestational Hormones, Synthetic Acta Endocrinol 75(2):385;1974 NLM TWD TWD M0050869 edogestrone C0603207 17-hydroxy- 6-methylpregn-5-ene-3,20-dione cyclic 3-(ethylene acetal) acetate 809-01-8 M0050869 M0050867 T080872 edogestrone Negwer #4498 T080871 edogesterone T080869 17 alpha-acetoxy-3,3-ethylenedioxy-6-methyl-5-pregnen-20-one M0050867 PH 218 C0603205 M0050869 M0050867 T080870 PH 218 C007480 2,5-dimethyl-1-pyrrolidinecarboxanilide 1975 01 01 1982 02 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PYRROLIDINES (75-82) *D000813 Anilides J Agr Food Chem 22(6):921;1974 NLM NBM NLM M0050708 2,5-dimethyl-1-pyrrolidinecarboxanilide C0603156 34484-77-0 T080711 2,5-dimethyl-1-pyrrolidinecarboxanilide C007486 dineuraminyllactose 1974 01 01 1982 09 21 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *OLIGOSACCHARIDES (74-75) LACTOSE (74-75) NEURAMINIC ACIDS (74-75) NEURAMINIC ACIDS (75-82) D007785 Lactose *Q000031 analogs ; derivatives NLM VSR NLM M0050716 dineuraminyllactose C0603158 0 T080719 dineuraminyllactose C007489 2,5-dinitrobenzoic acid 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *BENZOATES (74-75) NITRO CPDS (74-75) *D009579 Nitrobenzoates Biochim Biophys Acta 321(1):72;1973 NLM NLM M0050718 2,5-dinitrobenzoic acid C0603159 610-28-6 T080721 2,5-dinitrobenzoic acid C007491 5,7-dinitroindazole 1974 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 NITRO COMPOUNDS (74-82) *D007191 Indazoles Xenobiotica 3(8):511;1973 NLM VSR NLM M0050721 5,7-dinitroindazole C0603160 31208-76-1 T080724 5,7-dinitroindazole C007495 2,4-dinitrophenylmethylamine 1974 01 01 1982 09 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *NITROBENZENES (74-77) DINITROBENZENES (74-82) METHYLAMINES (74-77) *D008744 Methylamines J Agric Food Chem 22(3):528;1974 NLM VSR NLM M0050734 2,4-dinitrophenylmethylamine C0603164 2044-88-4 T080737 2,4-dinitrophenylmethylamine C007496 10-(2',4'-dinitrophenylthio)phenothiazine 1974 01 01 1982 09 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 NITROBENZENES (74-75) SULFIDES (74-82) *D010640 Phenothiazines Acta Pol Pharm 31(2):169;1974 NLM VSR NLM M0050735 10-(2',4'-dinitrophenylthio)phenothiazine C0603165 10H-Phenothiazine, 10-((2,4-dinitrophenyl)thio)- 54199-19-8 T080738 10-(2',4'-dinitrophenylthio)phenothiazine C007497 dinitrosodimethylethylenediamine 1975 01 01 1982 02 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ETHYLENEDIAMINES (75-82) *D009603 Nitroso Compounds Gig Sanit 9:80;1974 NLM NBM NLM M0050736 dinitrosodimethylethylenediamine C0603166 13256-12-7 T080739 dinitrosodimethylethylenediamine C007498 N,4-dinitrosomethylaniline 1974 01 01 1982 09 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ANILINE COMPOUNDS (74-82) *D009603 Nitroso Compounds Vopr Onkol 19(8):80;1973 NLM VSR NLM M0050737 N,4-dinitrosomethylaniline C0603167 99-80-9 T080740 N,4-dinitrosomethylaniline C007499 dinitrosopentamethylenetetramine 1975 01 01 1997 01 22 1997 1998 1999 2000 2001 2002 structure 2 *BICYCLO COMPOUNDS (83-95) NITROSO COMPOUNDS (75-82) *D019086 Bicyclo Compounds, Heterocyclic Bull Nat Inst Hyg Sci Jpn 93:51;1975 IARC Monogr Eval Carcinog Risk Chem Man 11:241;1976 J Biomed Res 8(5):214;1974 NLM MLH BVL M0050738 dinitrosopentamethylenetetramine C0058306 3,7-dinitroso-1,3,5,7-tetraazabicyclo(3.3.1)nonane 101-25-7 T080741 dinitrosopentamethylenetetramine C007507 8,8'-dioxo-6,6'-azopurine 1974 01 01 1997 08 14 1998 1999 2000 2001 2002 structure; curare antag 0 *AZO COMPOUNDS (74-82) *D011687 Purines D003472 Curare Q000037 antagonists ; inhibitors D014969 Xanthine Oxidase Q000037 antagonists ; inhibitors J Med Chem 17(6):639;1974 NLM MLH TPW M0050754 8,8'-dioxo-6,6'-azopurine C0603174 52583-98-9 T080757 8,8'-dioxo-6,6'-azopurine C052137 16,16-dimethyl-15-dehydroprostaglandin B1 trimer 1987 05 15 2001 08 02 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 6 *D011456 Prostaglandins B D007476 Ionophores Biochem Biophys Res Commun 1987;143(3):1024 RLS TWD TWD M0148112 16,16-dimethyl-15-dehydroprostaglandin B1 trimer C0044922 0 M0148112 M0148111 T178117 16,16-dimethyl-15-dehydroprostaglandin B1 trimer T178114 16,16-diMe-15-dehydro-PGB1 trimer T178115 16,16-diMePGB1 trimer M0148111 Tri-Calciphor C0164716 M0148112 M0148111 T178116 Tri-Calciphor C007511 dipasphene 1974 01 01 1995 07 27 1996 1997 1998 1999 2000 2001 2002 combination containing dibiomycin, aminosalicylic acid salt of dihydrostreptomycin, ; phenoxymethylpenicillin 0 *CHLORTETRACYCLINE (74-75) DRUG COMBINATIONS (74-88) D002751 Chlortetracycline Q000031 analogs ; derivatives D004096 Dihydrostreptomycin Sulfate D005029 Ethylenediamines D010404 Penicillin V Veterinariia 12(0):54;1973 NLM MLH BVL M0050767 dipasphene C0603175 37304-90-8 T080770 dipasphene C117144 Diva protein 1999 02 16 2000 10 10 1999 2000 2000A 2000B 2000C 2001 2002 a mouse Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death; amino acid sequence in both sources; GenBank AF067660(Diva) and AF102501(Boo) 4 *D019253 Proto-Oncogene Proteins c-bcl-2 D016923 Cell Death EMBO J 1999 Jan 4;18(1):167-78 J Biol Chem 1998 Dec 4;273(49):32479-86 BMB WXM WXM M0300821 Diva protein C0761382 0 T116 Amino Acid, Peptide, or Protein T123 Biologically Active Substance T329123 Diva protein T330826 Boo protein T329122 Diva gene product C007514 diphenylaminoethanol 1975 01 01 1994 09 19 1995 1996 1997 1998 1999 2000 2001 2002 GABA antagonist 0 BENZENE DERIVATIVES (75-76) *D004983 Ethanolamines Arch Int Pharmacodyn Ther 210(1):135;1974 NLM PML TPW M0050769 diphenylaminoethanol C0603177 6315-51-1 T080772 diphenylaminoethanol C007512 diphenyl N-1-adamantylphosphoramidate 1974 01 01 2000 10 09 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2000A 2001 2002 structure 0 ORGANOPHOSPHORUS COMPOUNDS (74-82) D000547 Amantadine *Q000031 analogs ; derivatives J Pharm Sci 62(10):1719;1973 NLM TWD TWD M0050768 diphenyl N-1-adamantylphosphoramidate C0603176 49802-24-6 T115 Organophosphorus Compound T121 Pharmacologic Substance T080771 diphenyl N-1-adamantylphosphoramidate C007518 1,1-diphenylethylene 1969 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 4 *D013343 Styrenes NLM NLM M0050775 1,1-diphenylethylene C0080381 530-48-3 T080778 1,1-diphenylethylene Merck Index, 9th ed, p. 444, #3331 C028217 cathepsin S 1981 02 20 2000 10 10 1995 1996 1997 1998 1999 2000 2000A 2001 2002 best substrate may be hemoglobin at pH 3; specificity unknown 136 *D002403 Cathepsins Ciba Found Symp 1979;75:13 RLS CCR CCR M0091040 cathepsin S C0054874 EC 3.4.22.27 T116 Amino Acid, Peptide, or Protein T126 Enzyme T121043 cathepsin S C007545 DNA-spermidine 1975 01 01 2001 03 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 used against radiation-induced leukopenia 1 DNA/*analogs (75-90) *D004247 DNA D013095 Spermidine *Q000031 analogs ; derivatives Nippon Acta Radiol 34(1):26;1974 NLM CCR CCR M0050813 DNA-spermidine C0058608 37217-88-2 M0050813 M0050811 T080816 DNA-spermidine T080815 spermidine-DNA M0050811 DA-51 C0112196 M0050813 M0050811 T080814 DA-51 C031187 14-deoxy-11,12-didehydroandrographolide 3,19-disuccinate 1981 08 27 2001 03 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 2 *D004224 Diterpenes Yao Hsueh Hsueh Pao 1980;15(10):590 RLS TWD TWD M0098181 14-deoxy-11,12-didehydroandrographolide 3,19-disuccinate C0614052 Butanedioic acid, mono((2-(3-carboxy-1-oxopropoxy)-5-(2-(2,5-dihydro-2-oxo-3-furanyl)ethenyl)decahydro-1,4a-dimethyl-6-methylene-1-naphthalenyl)methyl) ester, monopotassium salt, (1R-(1alpha,2alpha,4aalpha,5alpha(E),8abeta))- 76958-99-1 T128185 14-deoxy-11,12-didehydroandrographolide 3,19-disuccinate T128184 DDHADS C031188 veratrilogenin 1981 08 27 2001 03 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from roots of Veratrilla baillinii Franch.; structure given in first source 1 *D014966 Xanthenes D004365 Drugs, Chinese Herbal Yao Hsueh Hsueh Pao 1980;15(10):625 RLS TWD TWD M0098183 veratrilogenin C0614054 9H-Xanthen-9-one, 1,7-dihydroxy-3,4-dimethoxy- 76907-77-2 T128187 veratrilogenin T128186 1,7-dihydroxy-3,4-dimethoxyxanthone C094303 Thing1 protein 1995 07 26 2001 03 02 1995 1996 1997 1998 1999 2000 2001 2001A 2002 a member of the basic-helix-loop-helix transcription factors; amino acid sequence given in first source; GenBank U21226 5 *D004268 DNA-Binding Proteins *D014157 Transcription Factors D012097 Repressor Proteins Mol Cell Biol 1995 Jul;15(7):3813-22 BMB CCR CCR M0248483 Thing1 protein C0299055 0 T278488 Thing1 protein T278486 Th1 gene product T278487 Th1 protein C007532 discarine A 1974 01 01 1981 06 16 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 mixed type inhibitor of energy transfer in spinach chloroplasts; structure 0 *PEPTIDES, CYCLIC (74-81) INDOLES (74-75) *D000470 Alkaloids FEBS Letters 33(2):201;1973 Phytochemistry 11(3):1133;1972 NLM NBM NLM M0050794 discarine A C0058450 36211-12-8 T080797 discarine A C007534 5,5'-diselenobis(5-deoxy-alpha,beta-D-xylofuranose) 1974 01 01 1992 05 14 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 DEOXY SUGARS (74-75) SELENIUM (74-92) *D016566 Organoselenium Compounds D014994 Xylose *Q000031 analogs ; derivatives Carbohyd Res 29(1):252;1973 NLM MLH NLM M0050796 5,5'-diselenobis(5-deoxy-alpha,beta-D-xylofuranose) C0603185 0 T080799 5,5'-diselenobis(5-deoxy-alpha,beta-D-xylofuranose) C007540 2,4-dithiobiuret 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 26 *THIOUREA (74-75) D013890 Thiourea *Q000031 analogs ; derivatives J Ag Food Chem 21(5):753;1973 NLM NLM M0050803 2,4-dithiobiuret C0045527 541-53-7 T080806 2,4-dithiobiuret C094304 SoxLZ protein 1995 07 26 2001 03 02 1998 1999 2000 2001 2001A 2002 a rainbow trout SOX gene product expressed in testis; amino acid sequence in first source 2 *D004268 DNA-Binding Proteins *D006609 High Mobility Group Proteins D016350 Leucine Zippers Mol Cell Biol 1995 Jul;15(7):3759-66 BMB CCR CCR M0248486 SoxLZ protein C0299057 0 T278491 SoxLZ protein T278489 SOX-LZ gene product T278490 SOX-LZ protein C035860 9-hydroxy-11,15-dioxo-2,3,18,19-tetranorprost-5-ene-1,20-dioic acid 1982 10 28 2001 08 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 urinary metabolite of PGD2 14 *D011457 Prostaglandins D Methods Enzymol 1982;86:559 VSR TWD TWD M0109631 9-hydroxy-11,15-dioxo-2,3,18,19-tetranorprost-5-ene-1,20-dioic acid C0050129 Cyclopentanehexanoic acid, 2-(4-carboxy-2-butenyl)-3-hydroxy-gamma,5-dioxo-, (1R-(1alpha,2beta(Z),3beta))- 70803-92-8 T139635 9-hydroxy-11,15-dioxo-2,3,18,19-tetranorprost-5-ene-1,20-dioic acid T139632 9-HDTPD T139633 PGD-M T139634 prostaglandin D-M C007552 Dolestan 1975 01 01 1994 09 30 1995 1996 1997 1998 1999 2000 2001 2002 contains carbromal, bromisoval, ; acecarbromal 0 *CARBROMAL (75-94) UREA/*analogs (75) *D001968 Bromisovalum D004338 Drug Combinations D014508 Urea *Q000031 analogs ; derivatives Arch Kriminol 153(1):36;1974 NLM MLH TPW M0050823 Dolestan C0603193 52232-04-9 T080826 Dolestan C031904 CL 116069 1981 11 09 2001 08 02 1996 1997 1998 1999 2000 2001 2001A 2002 1 *D011459 Prostaglandins E, Synthetic Prostaglandins 1981;21(6):1015 RLS TWD TWD M0099898 CL 116069 C0614489 Cyclopentanone, 4-hydroxy-2-(8-hydroxy-7-oxo-2-octenyl)-3-(3-hydroxy-4-phenoxy-1-butenyl)-, (2alpha(Z),3beta(1E,3R*),4alpha)-(+-)- 79378-27-1 M0099898 M0099895 T129902 CL 116069 T129900 CL 116,069 T129901 CL-116069 M0099895 1,9-dioxo-11 alpha,15 alpha-dihydroxy-1-hydroxymethyl-16-phenoxy-17,18,19,20-tetranor-5,13-prostadiene C0614486 M0099898 M0099895 T129899 1,9-dioxo-11 alpha,15 alpha-dihydroxy-1-hydroxymethyl-16-phenoxy-17,18,19,20-tetranor-5,13-prostadiene C007574 echinopsine 1969 01 01 1993 05 17 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 *QUINOLINES (69-88) *D015363 Quinolones Acta Physiol Pharmacol Bulg 1979;5(1):41 Acta Physiol Pharmacol Bulg 1979;5(4):13 Acta Physiol Pharmacol Bulg 2(4):59;1976 Eksp Med Morfol 17(1):18;1978 Eksp Med Morfol 17(4):202;1978 NLM BXB TPW M0050861 echinopsine C0058922 1-methyl-4(1H)-quinolone 83-54-5 T080864 echinopsine Merck Index, 9th ed, p. 462, #3467 C007575 ecmonovocillin 1967 01 01 1982 07 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 *D010402 Penicillin G, Procaine D008110 Liver Extracts Vestn Dermatol 47(5);1973 NLM CHA NLM M0050862 ecmonovocillin C0058932 12645-23-7 T080865 ecmonovocillin Russian Drug Index C431792 BMAL2 protein 2001 08 02 2001 2002 aryl hydrocarbon receptor nuclear translocator; amino acid sequence in first source 3 *D014157 Transcription Factors D018257 Helix-Loop-Helix Motifs Neurosci Lett 2001 Mar 9;300(2):111-4 SXK SXK M0394670 BMAL2 protein C0968223 0 T116 Amino Acid, Peptide, or Protein T456143 BMAL2 protein 2001 08 02 T456144 Arnt4 protein 2001 08 02 T456145 Brain-Muscle-Arnt-Like-protein 2 2001 08 02 C007590 emulphogene BC 720 1974 01 01 1998 09 03 1998 1999 2000 2001 2002 a polyether detergent; RN given refers to cpd with unspecified isomeric designation 7 *ETHERS (74-79) *POLYOXYETHYLENES (77-80) *D011092 Polyethylene Glycols Biochemistry 13(4):738;1974 J Pharm Sci 65(11):1639;1976 NLM BVL NLM M0050883 emulphogene BC 720 C0059085 24938-91-8 69011-36-5 (branched isomer) M0050883 M0050880 M0050883 M0050882 M0050883 M0309999 M0050883 M0050881 T080886 emulphogene BC 720 M0050880 Renex 30 C0140192 M0050883 M0050880 T080883 Renex 30 M0050882 polyoxyethylene tridecyl ether C0137841 M0050883 M0050882 T080885 polyoxyethylene tridecyl ether M0309999 branched isomer of emulphogene BC 720 C0895358 69011-36-5 M0050883 M0309999 T339999 branched isomer of emulphogene BC 720 1999 08 18 M0050881 polyoxyethylene 6-tridecyl ether C0137836 M0050883 M0050881 T080884 polyoxyethylene 6-tridecyl ether C007594 enmein 1975 01 01 1997 09 02 1997 1998 1999 2000 2001 2002 structure 2 ETHERS, CYCLIC (75-82) *D004224 Diterpenes Chem Pharm Bull 22(7):1656;1974 NLM MLH NLM M0050887 enmein C0059359 3776-39-4 T080890 enmein C007598 entero-oxyntin 1975 01 01 1986 04 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 peptide hormone from intestine which stimulates oxyntic cells 15 *D010455 Peptides D005768 Gastrointestinal Hormones Ann Surg 188(2):181;1978 Gastroenterology 67(4):754;1974 Scand J Gastroenterol 1980;15(1):17 Surgery 77(6):841;1975 NLM RLS NLM M0050890 entero-oxyntin C0059380 Oxyntin, entero- 59828-38-5 M0050890 M0050888 M0050890 M0050889 T080893 entero-oxyntin M0050888 oxyntin C0134430 M0050890 M0050888 T080891 oxyntin M0050889 porcine ileal polypeptide C0137952 M0050890 M0050889 T080892 porcine ileal polypeptide C007599 enzacryl AA 1975 01 01 1982 02 10 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 used as support for immobilization of brinolase; cross-linked polymer of acrylamide in which a fraction of the pendant amide groups has been substituted with p-phenylenediamine 0 ACRYLAMIDES (75-76) PHENYLENEDIAMINES (75-82) *D000180 Acrylic Resins J Biomed Mat Res 8(5):261;1974 NLM NBM NLM M0050891 enzacryl AA C0603213 37265-17-1 T080894 enzacryl AA C007605 14,15-epoxygeranylgeraniol 1974 01 01 1986 12 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 prevents percutaneous Schistosoma mansoni cercariae penetration; structure 0 *TERPENES (74-75) EPOXY COMPOUNDS (74-82) ETHERS, CYCLIC (74-75) *D004224 Diterpenes D010938 Plant Oils Am J Trop Med Hyg 22(6):743;1973 NLM MEG NLM M0050892 14,15-epoxygeranylgeraniol C0044846 13-(3,3-dimethyloxiranyl)-3,7,11-trimethyl-2,6,10- tridecatrien-1-ol 14760-52-2 T080895 14,15-epoxygeranylgeraniol C025118 cholyl CoA glycine-taurine N-acyltransferase 1980 07 01 2001 01 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 15 GLYCOCHOLIC ACID (79-80) TAUROCHOLIC ACID (79-80) *D000217 Acyltransferases J Biol Chem 1980;255(11):5296 MEG WXM WXM M0084129 cholyl CoA glycine-taurine N-acyltransferase C0055581 EC 2.3.1.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T114132 cholyl CoA glycine-taurine N-acyltransferase T114128 bile acid-CoA glycine taurine N-acyltransferase T114127 CCAGT acyltransferase T114129 cholyl CoA glycine-N-acyltransferase T114130 cholyl CoA taurine-N-acyltransferase T114131 cholyl coenzyme A glycine-taurine N-acyltransferase C007607 2',3'-epoxypropylglucopyranoside 1974 01 01 1997 01 03 1997 1998 1999 2000 2001 2002 active-site directed, irreversible inactivator of yeast hexokinase; structure 3 *GLYCOSIDES (74-75) EPOXY COMPOUNDS (75-82) ETHERS, CYCLIC (74-75) *D005960 Glucosides Biochim Biophys Acta 331(2):327;1973 NLM MLH NLM M0050898 2',3'-epoxypropylglucopyranoside C0045124 beta-D-Glucopyranoside, oxiranylmethyl 33275-57-9 M0050898 M0050897 M0050898 M0050896 T080901 2',3'-epoxypropylglucopyranoside M0050897 2',3'-epoxypropyl-beta-D-glucopyranoside C0090968 M0050898 M0050897 T080900 2',3'-epoxypropyl-beta-D-glucopyranoside M0050896 2',3'-epoxypropyl-alpha-D-glucopyranoside C0090967 M0050898 M0050896 T080899 2',3'-epoxypropyl-alpha-D-glucopyranoside C007606 1,2-epoxy-3-(p-nitrophenoxy)propane 1974 01 01 2001 01 12 1997 1998 1999 2000 2001 2001A 2002 a protease inhibitor 30 *PROPANE (74-75) EPOXY COMPOUNDS (74-82) PHENYL ETHERS (74-77) PROPANE/*analogs (75-77) *D009596 Nitrophenols D004852 Epoxy Compounds Biochim Biophys Acta 480:262;1977 Can J Biochem 52(11):1018;1974 J Biochem (Tokyo) 74(2):231;1973 J Biochem (Tokyo) 80(5):975-983;1976 J Biochem (Tokyo) 81:805;1977 J Biochem (Tokyo) 83(2):441;1978 J Biochem (Tokyo) 84(6):1593;1978 Nature 267(5614):808;1977 Xenobiotica 8(4):219;1978 NLM CCR CCR M0050895 1,2-epoxy-3-(p-nitrophenoxy)propane C0043858 5255-75-4 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid D007202 Indicators and Reagents D011480 Protease Inhibitors T080898 1,2-epoxy-3-(p-nitrophenoxy)propane T080896 EPNP T080897 glycidyl 4-nitrophenyl ether C033588 dihydrolipoamide acyltransferase 1982 03 12 2001 01 12 1997 1998 1999 2000 2000A 2001 2001A 2002 component of branched-chain 2-oxo acid dehydrogenase multienzyme complex; mutation in this (E2) catalytic subunit identifies type II maple syrup urine disease; do not confuse with E2 enzymes of pyruvate dehydrogenase (PDC) and alpha-ketoglutarate dehydrogenase complexes 41 *D000217 Acyltransferases Biochem J 1981;200(1):59 MEG WXM WXM M0104140 dihydrolipoamide acyltransferase C0058088 EC 2.3.1.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T134144 dihydrolipoamide acyltransferase T422392 BCOADC-E2 2000 08 22 T134143 dihydrolipoyl transacylase T134141 E2 transacylase T134142 branched chain acyltransferase C007611 eremuran 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D011134 Polysaccharides Biokhimiia 38(1):52;1973 NLM NLM M0050910 eremuran C0603214 Eremuran 39300-86-2 T080913 eremuran C007614 ergostanol 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 D004875 Ergosterol *Q000031 analogs ; derivatives Lipids 9(8):625;1974 NLM NLM M0050911 ergostanol C0603215 5 alpha-ergostan-3 beta-ol 516-76-7 T080914 ergostanol Merck Index, 9th ed, p. 478, #3576 C007620 erybidine 1974 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ANISOLES (74-81) *D000470 Alkaloids D004895 Erythrina J Pharm Soc Jpn 93(3):1218;1973 NLM VSR NLM M0050918 erybidine C0603218 5H-Dibenz(d,f)azonin-3-ol, 6,7,8,9-tetrahydro-2,11,12-trimethoxy-7-methyl- 34083-19-7 T080921 erybidine C007622 erythrinine 1974 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 erythrina alkaloid; structure 0 *INDOLES (74-81) DIOXOLES (74-75) *D000470 Alkaloids D004895 Erythrina J Pharm Soc Jpn 93(3):1215;1973 NLM VSR NLM M0050920 erythrinine C0603220 29306-29-4 T080923 erythrinine C007632 17 beta-estradiol 3-tetrahydropyranyl ether 1974 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *ESTRADIOL (74-75) PYRANS (74-82) D004958 Estradiol *Q000031 analogs ; derivatives Minerva Ginecol 24(2):70;1972 NLM VSR NLM M0050938 17 beta-estradiol 3-tetrahydropyranyl ether C0603225 3589-90-0 T080941 17 beta-estradiol 3-tetrahydropyranyl ether C007637 ethadione 1969 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 *D010080 Oxazoles NLM NLM M0050957 ethadione C0059690 3-ethyl-5,5-dimethyl-2,4-oxazolidinedione 520-77-4 T080960 ethadione Merck Index, 9th ed, p. 489, #3644 C007641 1,N(6)-etheno-2-azaadenosine 3',5'-monophosphate 1975 01 01 1993 09 07 1994 1995 1996 1997 1998 1999 2000 2001 2002 fluorescent substrate for cyclic nucleotide phosphodiesterase; structure 0 AZA COMPOUNDS (76-82) IMIDAZOLES (75-76) D000242 Cyclic AMP *Q000031 analogs ; derivatives Anal Biochem 60(1):163;1974 NLM PML TPW M0050963 1,N(6)-etheno-2-azaadenosine 3',5'-monophosphate C0603226 3H-Diimidazo(1,2-c 4',5'-e)(1,2,3)triazine, 3-(3,5-O-phosphinico-beta-D-ribofuranosyl)- 50663-90-6 T080966 1,N(6)-etheno-2-azaadenosine 3',5'-monophosphate C100125 ormetoprim 1984 08 14 2001 01 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 proposed chemotherapeutic agent; minor descriptor (75-84); on-line ; Index Medicus search PYRIMIDINES (75-84) 19 minor descriptor (75-84); file-maintained to PYRIMIDINES *D011743 Pyrimidines GTC TWD TWD M0262729 ormetoprim C0069647 6981-18-6 T109 Organic Chemical T121 Pharmacologic Substance T292734 ormetoprim USAN 1984, p.351 T292733 2,4-diamino-5-(6-methylveratryl)pyrimidine C007646 ethoxyd 1974 01 01 1976 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PHENYLTHIOUREA (74-76) ETHYL ETHERS (74-76) D010670 Phenylthiourea *Q000031 analogs ; derivatives Farmakol Toksikol 38(2):222;1975 NLM NLM M0050972 ethoxyd C0059731 4,4'-diethoxythiocarbanilide 1234-30-6 T080975 ethoxyd Negwer 2793 C007648 2-ethoxyethylamine 1974 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ETHYL ETHERS (74-82) *D005021 Ethylamines Biochim Biophys Acta 321(1):382;1973 NLM VSR NLM M0050974 2-ethoxyethylamine C0603231 Ethanamine, 2-ethoxy- 110-76-9 T080977 2-ethoxyethylamine C007655 2-ethyl-2H,3H-benzimidazo-(1,2b)oxazole 1975 01 01 1982 03 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *BENZIMIDAZOLES *D010080 Oxazoles Il Farmaco 29(12):910;1974 NLM MGR NLM M0050989 2-ethyl-2H,3H-benzimidazo-(1,2b)oxazole C0603234 Oxazolo(3,2-a)benzimidazole, 2-ethyl-2,3-dihydro- 54700-19-5 T080992 2-ethyl-2H,3H-benzimidazo-(1,2b)oxazole C007663 O(2')(3')-(ethyl-2-diazomalonyl)adenosine 5'-monophosphate 1974 01 01 1982 09 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 potential photoaffinity reagent for characterization of binding, allosteric sites; structure 0 *AMP (74-75) DIAZONIUM COMPOUNDS (74-82) MALONATES (74-75) D000249 Adenosine Monophosphate *Q000031 analogs ; derivatives Biochemistry 12(21):4074;1973 NLM VSR NLM M0051001 O(2')(3')-(ethyl-2-diazomalonyl)adenosine 5'-monophosphate C0603241 5'-Adenylic acid, mono(ethyl diazopropanedioate) (ester) 50769-45-4 T081004 O(2')(3')-(ethyl-2-diazomalonyl)adenosine 5'-monophosphate C007666 N,N'ethylene bis(trifluoroacetylacetoiminato)copper(II) 1974 01 01 1998 01 08 1998 1999 2000 2001 2002 0 FLUOROACETATES (74-82) *D009942 Organometallic Compounds D003300 Copper J Am Chem Soc 96(4):1019;1974 NLM BQV NLM M0051005 N,N'ethylene bis(trifluoroacetylacetoiminato)copper(II) C0603245 Copper, ((4,4'-(1,2-ethanediyldinitrilo)bis(1,1,1-trifluoro-2-pentanonato))(2-)-N,N',O,O')-, (SP-4-2)- 40820-17-5 T081008 N,N'ethylene bis(trifluoroacetylacetoiminato)copper(II) C007671 1-O-ethyl-D-glucofuranouronic acid para-ethoxyphenylhydrazide 1974 01 01 1983 08 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 GLYCOSIDES (74-75) *D005965 Glucuronates *D010659 Phenylhydrazines D008833 Microcirculation Q000187 drug effects NLM ACS NLM M0051007 1-O-ethyl-D-glucofuranouronic acid para-ethoxyphenylhydrazide C0603246 D-Glucofuranosiduronic acid, ethyl, 2-(4-ethoxyphenyl)hydrazide 78608-65-8 T081010 1-O-ethyl-D-glucofuranouronic acid para-ethoxyphenylhydrazide C007672 S-(2-ethylguanidine)phosphorothioic acid 1975 01 01 1982 03 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 ORGANOTHIOPHOSPHORUS COMPOUNDS *D006146 Guanidines Cancer Res 35(2):429;1975 NLM MGR NLM M0051008 S-(2-ethylguanidine)phosphorothioic acid C0603247 Guanidine, (2-(phosphonothio)ethyl)- 54978-25-5 T081011 S-(2-ethylguanidine)phosphorothioic acid C007680 ethyl palmitate 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 16 *D010169 Palmitic Acids Acta Biol Med Ger 37(1):127;1978 NLM NLM M0051023 ethyl palmitate C0059780 628-97-7 T081026 ethyl palmitate C007684 2-S-ethyl-2-thio-D-mannose diethyl dithioacetal 1974 01 01 1982 09 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *MANNOSE (74-75) ACETALS (74-75) MANNOSE/analogs (75-82) *D013865 Thioglycosides Carbohyd Res 29(1):276;1973 NLM VSR NLM M0051025 2-S-ethyl-2-thio-D-mannose diethyl dithioacetal C0603251 D-Mannose, 2-S-ethyl-2-thio-, diethyl mercaptal 15356-41-9 T081028 2-S-ethyl-2-thio-D-mannose diethyl dithioacetal C007686 5-etienic acid 1975 01 01 1982 02 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 CARBOXYLIC ACIDS (75-82) *D000736 Androstenes Steroids Lipids Res 5(2):101;1974 NLM NBM NLM M0051027 5-etienic acid C0049171 5-androstene-17 beta-carboxylic acid 438-10-8 T081030 5-etienic acid C007691 acetylpyruvic acid 1975 01 01 1980 11 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 4 *D011773 Pyruvates J Biol Chem 250(10):3826;1975 NLM RLS NLM M0051034 acetylpyruvic acid C0050533 2,4-dioxovalerate 5699-58-1 M0051034 M0051033 T081037 acetylpyruvic acid M0051033 acetopyruvate C0101099 M0051034 M0051033 T081036 acetopyruvate C007693 euparone 1975 01 01 1982 02 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 from Ruscus aculeatus L.; structure 1 ACETIC ACIDS (75-82) *D001572 Benzofurans J Pharm Sci 63(10):1623;1974 NLM NBM NLM M0051035 euparone C0059899 2,5-diacetyl-6-hydroxybenzofuran 53947-86-7 T081038 euparone C007746 5-fluoro-2'-deoxycytidine 1974 01 01 2000 12 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 28 *DEOXYRIBONUCLEOSIDES (74-76) DEOXYCYTIDINE (74-76) FLUORINE (74-76) D003841 Deoxycytidine *Q000031 analogs ; derivatives Virchows Arch 1979;382(3):271 Z Versuchstierkd 28(1-2):32;1976 NLM CCR CCR M0051113 5-fluoro-2'-deoxycytidine C0049174 10356-76-0 T114 Nucleic Acid, Nucleoside, or Nucleotide T081116 5-fluoro-2'-deoxycytidine T081115 2'-deoxy-5-fluorocytidine C007700 Exrheudon-salbe 1974 01 01 1982 10 07 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 combination ointment used in rheumatism therapy; contains nicotinic acid benzyl ester, capsicin, monoglycosalicylate, menthylsalicylate 0 *D002212 Capsicum *D009539 Nicotinic Acids *D012459 Salicylates D004338 Drug Combinations D010936 Plant Extracts Z Allgemein Med 49(22):1049;1973 NLM VSR NLM M0051042 Exrheudon-salbe C0603255 0 T081045 Exrheudon-salbe C061897 Rad3 ATPase-DNA helicase 1990 01 03 2000 12 20 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 can unwind duplex regions as short as 11 base pairs in a partially duplex circular DNA substrate; on partially duplex linear substrates, the enzyme has a strict 5'--3' polarity with respect to the single strand to which it binds; Nicked circular DNA is not utilized; from Saccharomyces cerevisiae 58 *D000251 Adenosinetriphosphatase *D004265 DNA Helicases J Biol Chem 1989;264(34):20532 TPW CCR CCR M0171518 Rad3 ATPase-DNA helicase C0072957 EC 3.6.1.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T201523 Rad3 ATPase-DNA helicase T201522 Rad3 protein C007751 5-fluoronicotinyl alcohol 1974 01 01 2001 02 02 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure; RN given refers to parent cpd 1 *PYRIDINES (74-75) ALCOHOL, METHYL (74-75) FLUORINE (74-75) D009540 Nicotinyl Alcohol *Q000031 analogs ; derivatives J Chromatogr 1980;187(1):189 Lancet 2(7833):814;1973 NLM TWD TWD M0051118 5-fluoronicotinyl alcohol C0049185 5-fluoro-3-hydroxymethylpyridine 22620-32-2 22620-33-3 (HCl) M0051118 M0310036 T081121 5-fluoronicotinyl alcohol M0310036 5-fluoronicotinyl alcohol hdyrochloride C0951725 22620-33-3 M0051118 M0310036 T340036 5-fluoronicotinyl alcohol hdyrochloride 1999 08 18 C007707 fenazaflor 1974 01 01 1998 11 09 1999 2000 2001 2002 2 *PESTICIDES (74-75) HYDROCARBONS, FLUORINATED (74-75) *D001562 Benzimidazoles Arch Int Pharmacodyn 203(2):342;1973 Survival Toxic Environ WA 670 S963:167;1973 NLM BQV NLM M0051054 fenazaflor C0060153 5,6-dichloro-1-phenoxycarbonyl-2-trifluoromethylbenzimidazole 14255-88-0 M0051054 M0051053 T081057 fenazaflor M0051053 phenofluorazole C0136572 M0051054 M0051053 T081056 phenofluorazole C007709 fencamine 1975 01 01 1994 06 22 1995 1996 1997 1998 1999 2000 2001 2002 psychotonic, defatigant deriv of caffeine ; ethylenediamine; structure 0 *ETHYLENEDIAMINES (75-82) D002110 Caffeine *Q000031 analogs ; derivatives Arzneim Forsch 24(9):1301;1974 NLM MLH TPW M0051055 fencamine C0603257 8-(2-(N-methyl-beta-phenyl-alpha-methylethylamine)ethylamine)-1,3,7-trimethyl-2,6-dioxopurine 24356-67-0 T081058 fencamine Negwer, 4th ed, #3632 C419466 fumiquinazoline I 2001 02 05 2001 02 05 2001 2001A 2002 structure in first source 1 *D011799 Quinazolines D011949 Receptors, Cholecystokinin Q000037 antagonists ; inhibitors Org Lett 2000 Dec 14;2(25):4103-6 SZM SZM SZM M0377979 fumiquinazoline I C0963843 0 T109 Organic Chemical T435275 fumiquinazoline I 2001 02 05 C007713 fentichlor 1968 01 01 1982 02 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 10 *PHENOLS (72-77) CHLORINE (72-77) SULFIDES (68-82) *D002733 Chlorophenols J Invest Dermatol 72(2):99;1979 Proc Roy Soc Med 69(5):379;1976 NLM NBM NLM M0051062 fentichlor C0060202 bis(2-hydroxy-5-chlorophenyl)sulfide 97-24-5 T081065 fentichlor C007715 ferrimycobactin P 1974 01 01 1997 07 14 1998 1999 2000 2001 2002 iron-containing form of mycobactin P 1 *FERRIC COMPOUNDS (74-82) AZEPINES (74-75) *D010080 Oxazoles D006133 Growth Substances D009161 Mycobacterium Biochem Biophys Res Commun 57(1):73;1974 NLM NNS BVL M0051064 ferrimycobactin P C0060254 Iron, (mycobactin P-ato)-, (OC-6-25)- 52282-31-2 T081067 ferrimycobactin P C064975 RecQ protein 1990 08 22 2000 12 20 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from E coli; member of the RecF recombination gene family; exhibits DNA-dependent ATPase ; a helicase activity 63 *D000251 Adenosinetriphosphatase *D004265 DNA Helicases Proc Natl Acad Sci USA 1990;87(14):5363 TPW CCR CCR M0178844 RecQ protein C0084304 EC 3.6.1.- T116 Amino Acid, Peptide, or Protein T126 Enzyme T208849 RecQ protein C419468 fumiquinazoline A 2001 02 05 2001 2002 structure in first source 1 *D011799 Quinazolines D011949 Receptors, Cholecystokinin Q000037 antagonists ; inhibitors Org Lett 2000 Dec 14;2(25):4103-6 SZM SZM M0377981 fumiquinazoline A C0963845 0 T109 Organic Chemical T435277 fumiquinazoline A 2001 02 05 C001632 4-methyl-alpha-ethyl-m-tyramine 1972 01 01 2001 02 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2001B 2002 serotonin-releasing agent; RN given refers to parent cpd; structure 10 *P-HYDROXYAMPHETAMINE/analogs (77-79) *PHENETHYLAMINES (75-83) *TYRAMINE (72-75) TYRAMINE/*analogs (75-77) *D000662 Amphetamines Arch Int Pharmacodyn Ther 227:324;1977 Arzneim Forsch 25(11):1758;1975 Can J Physiol Pharmacol 54(4):494;1976 Eur J Pharmacol 19(1):25;1972 J Pharm Pharmacol 26(10):781;1974 J Pharm Pharmacol 28(8):649;1976 Naunyn Schmiedebergs Arch Pharmacol 287(3):233;1975 Pharmacol Res Commun 8(4):387;1976 Psychopharmacology 47(1):33;1976 NLM jmp jmp M0041891 4-methyl-alpha-ethyl-m-tyramine C0097242 5-(2-aminobutyl)-2-methylphenol 22173-84-8 T109 Organic Chemical T121 Pharmacologic Substance 29440-91-3 (HCl) M0041891 M0041895 M0041891 M0307709 T071894 4-methyl-alpha-ethyl-m-tyramine T071897 alpha-ethyl-4-methylmetatyramine M0041895 H 75-12 C0282720 0 T109 Organic Chemical T121 Pharmacologic Substance M0041891 M0041895 T071898 H 75-12 T071895 H75-12 M0307709 alpha-ethyl-3-hydroxy-4-methylphenethylamine hydrochloride C0969857 29440-91-3 T109 Organic Chemical T121 Pharmacologic Substance M0041891 M0307709 T071896 alpha-ethyl-3-hydroxy-4-methylphenethylamine hydrochloride C007730 florenal 1975 01 01 1982 02 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 4 GLYOXAL/analogs (75-82) *D005449 Fluorenes Stomatologiia (Mosk) 53(5):61;1974 Vopr Virusol 5:544;1978 NLM NBM NLM M0051084 florenal C0060465 2-fluorenoyl glyoxal 42834-66-2 T081087 florenal UD 26:23 d C007731 florigrandin 1974 01 01 1981 11 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 antileukemic agent isolated from Hymenoxy grandiflora; structure 0 *ANTINEOPLASTIC AGENTS (74-75) LACTONES (74-81) *D012717 Sesquiterpenes J Org Chem 39(14):2013;1974 NLM NBM NLM M0051085 florigrandin C0603267 51292-61-6 T081088 florigrandin C007738 fluoranthene 1969 01 01 1998 05 27 1998 1999 2000 2001 2002 structure 107 *D005449 Fluorenes Carcinogenesis W1 CA7624:288;1976 Zentralbl Bakteriol Parasitol Infekt 161(4):304;1976 Zentralbl Bakteriol Parasitol Infekt 162(1-2):225;1976 Zentralbl Bakteriol Parasitol Infekt 164(5-6):469;1977 NLM SZM NLM M0051097 fluoranthene C0060514 206-44-0 D004791 Enzyme Inhibitors T081100 fluoranthene C007739 fluorenylhydroxamic acid 1974 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 induces mammary tumors in rats 3 HYDROXAMIC ACIDS (74-82) *D005449 Fluorenes Cancer Res 33(10):2489;1973 NLM VSR NLM M0051098 fluorenylhydroxamic acid C0060519 0 T081101 fluorenylhydroxamic acid C007741 fluoroacetamide 1974 01 01 1982 02 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 13 AMIDES (74-82) *D005463 Fluoroacetates J Wildlife Diseases 11(4):534;1975 NLM NBM NLM M0051101 fluoroacetamide C0060553 640-19-7 T081104 fluoroacetamide C009378 taondiol 1974 01 01 2001 02 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 isolated from marin alga Taonia atomaria 0 *XANTHENES (74-79) NAPHTHALENES (74-79) *D004224 Diterpenes J Chem Soc (Perkin I):22:2637;1973 NLM TWD TWD M0054022 taondiol C0603967 34274-99-2 T084025 taondiol T084024 2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,8,12b-hexamethyl-1H-naphthol(2,1-a) xanthen-2,10-diol C061759 vasopressin, N,N-diethylamide 1-(1-mercaptocyclohexaneacetic acid)-2-O-methyl-Tyr-4-glutamic acid (gamma-N,N-diethylamide)-8-Arg- 1989 12 20 2001 02 05 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source; arginine vasopressin antagonist 1 D001127 Argipressin *Q000031 analogs ; derivatives Pol J Pharmacol Pharm 1989;41(1):97 WMM CCR CCR M0171170 vasopressin, N,N-diethylamide 1-(1-mercaptocyclohexaneacetic acid)-2-O-methyl-Tyr-4-glutamic acid (gamma-N,N-diethylamide)-8-Arg- C0638748 125443-55-2 T201175 vasopressin, N,N-diethylamide 1-(1-mercaptocyclohexaneacetic acid)-2-O-methyl-Tyr-4-glutamic acid (gamma-N,N-diethylamide)-8-Arg- T201174 N,N-diethylamide 1-(1-mercaptocyclohexaneacetic acid)-2-O-methyltyrosine-4-glutamic acid (gamma-N,N-diethylamide)-8-arginine-vasopressin T201173 DMMTGD-argipressin C007750 fluorohydroxyandrostenedione 1975 01 01 1982 12 23 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 HYDROXYSTEROIDS (75-76) STEROIDS, FLUORINATED (75-76) D000735 Androstenedione *Q000031 analogs ; derivatives J Repr Fert 39(2):319;1974 NLM MEG NLM M0051117 fluorohydroxyandrostenedione C0603272 357-09-5 T081120 fluorohydroxyandrostenedione C007756 5-fluoropolyoxin C 1974 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *URIDINE (74-75) GLYCINE (74-75) D014529 Uridine Q000031 analogs ; derivatives J Am Chem Soc 95(17):5788;1973 NLM VSR NLM M0051128 5-fluoropolyoxin C C0603276 0 T081131 5-fluoropolyoxin C C007776 (5)N-formyl-tetrahydropteroyl-polyglutamate 1975 01 01 1989 09 29 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *TETRAHYDROFOLATES (74-75) GLUTAMATES (75-79) POLYGLUTAMIC ACID/analogs (75-82) D002955 Leucovorin *Q000031 analogs ; derivatives Fed Proc 32(12):2148;1973 NLM RJM RLS M0051155 (5)N-formyl-tetrahydropteroyl-polyglutamate C0043616 0 T081158 (5)N-formyl-tetrahydropteroyl-polyglutamate C007786 Frigen 113 TR 1970 01 01 1994 08 10 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 19 *HYDROCARBONS, HALOGENATED (70-75) *D005617 Chlorofluorocarbons, Methane NLM PML NLM M0051184 Frigen 113 TR C0060762 76-13-1 M0051184 M0051183 M0051184 M0051182 M0051184 M0051181 T081187 Frigen 113 TR M0051183 Freon 113 C0118235 M0051184 M0051183 T081186 Freon 113 M0051182 CFC 113 C0243288 M0051184 M0051182 T081185 CFC 113 M0051181 1,1,2-trichloro-1,2,2-trifluoroethane C0087813 M0051184 M0051181 T081184 1,1,2-trichloro-1,2,2-trifluoroethane C007787 frullanolide 1974 01 01 1982 12 17 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 allergenic; structure 2 LACTONES (74-81) *D012717 Sesquiterpenes D000485 Allergens J Org Chem 39(2):186;1974 NLM VSR NLM M0051185 frullanolide C0060782 27579-97-1 T081188 frullanolide C007790 fucosylglycolipids 1974 01 01 1987 08 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 FUCOSE (74-81) *D006017 Glycolipids D002518 Ceramides Nature 248(450):682;1974 NLM DLV NLM M0051195 fucosylglycolipids C0060807 0 M0051195 M0051194 M0051195 M0051193 T081198 fucosylglycolipids M0051194 complex fucolipid II C0110543 M0051195 M0051194 T081197 complex fucolipid II M0051193 ceramide eikosahexoside C0109062 M0051195 M0051193 T081196 ceramide eikosahexoside C007883 gramesol 1974 01 01 2000 12 05 1996 1997 1998 1999 2000 2001 2001A 2002 mixture of gramicidin, anesthesin(Benzocaine), menthol ; ethyl alcohol; Russian drug 0 *D001566 Benzocaine *D006096 Gramicidin D004338 Drug Combinations Vestn Otorinolaringol 35(1):33;1975 NLM TWD TWD M0051339 gramesol C0603325 0 T109 Organic Chemical T121 Pharmacologic Substance T081342 gramesol C007793 furacrylan 1974 01 01 1984 02 21 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 NITROFURANS (74-82) D014230 Triazoles Zh Mikrobiol Epidemiol Immunobiol 50(2):98;1973 NLM DLJ NLM M0051201 furacrylan C0060847 1-(5-nitro-2-furylacrylidenamino)-1,3,4-triazole 10048-74-5 T081204 furacrylan C010471 hyodeoxycholic acid 1975 01 01 2000 12 13 1998 1999 2000 2001 2001A 2002 differs from deoxycholic acid in that the 6 alpha-OH is in the 12 position in the former; RN given refers to (3alpha,5beta,6alpha)-isomer 51 ISOMERISM (75-80) *D003840 Deoxycholic Acid J Steroid Biochem 1979;11(3):1227 Lipids 11(2):93;1976 Pharmazie 30(1):22;1975 Pharmazie 30(8):506-12;1975 Pharmazie 32(3):146;1977 Steroids 1979;34(6):717 Steroids 32(5):589;1978 NLM CCR CCR M0055990 hyodeoxycholic acid C0063208 3 alpha,6 alpha-dihydroxy- 5 beta-cholan-24-oic acid 83-49-8 T109 Organic Chemical 10421-49-5 (Na salt) 15076-13-8 ((3alpha,6beta)-isomer) 668-49-5 ((3alpha,5beta,6beta)-isomer) M0055990 M0311129 M0055990 M0311128 M0055990 M0055987 M0055990 M0311127 T085993 hyodeoxycholic acid Merck Index, 9th ed, p. 647, #4779 T085991 hyodesoxycholic acid M0311129 hyodeoxycholic acid, (3alpha,5beta,6beta)-isomer C0206929 668-49-5 T109 Organic Chemical M0055990 M0311129 T341129 hyodeoxycholic acid, (3alpha,5beta,6beta)-isomer 1999 08 18 T085992 murideoxycholic acid M0311128 hyodeoxycholic acid, (3alpha,6beta)-isomer C0952115 15076-13-8 T109 Organic Chemical M0055990 M0311128 T341128 hyodeoxycholic acid, (3alpha,6beta)-isomer 1999 08 18 M0055987 3,6-dihydroxy-5alpha-cholanoic acid C0243359 T109 Organic Chemical M0055990 M0055987 T085990 3,6-dihydroxy-5alpha-cholanoic acid M0311127 hyodeoxycholic acid, sodium salt C0952114 10421-49-5 T109 Organic Chemical M0055990 M0311127 T341127 hyodeoxycholic acid, sodium salt 1999 08 18 C007797 furazanobenzofuroxan 1974 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CYCLIC N-OXIDES (74-82) *D010069 Oxadiazoles J Med Chem 17(2):203;1974 NLM VSR NLM M0051215 furazanobenzofuroxan C0603288 5714-13-6 T081218 furazanobenzofuroxan C007798 furazanobenzothiadiazole 1974 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 OXADIAZOES (74-82) *D013830 Thiadiazoles J Med Chem 17(2):203;1974 NLM VSR NLM M0051216 furazanobenzothiadiazole C0603289 33066-35-2 T081219 furazanobenzothiadiazole C007801 furazonal 1974 01 01 1982 03 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *TRIAZOLES *D009581 Nitrofurans Farm Zh 27(2):20;1972 NLM MGR NLM M0051218 furazonal C0060858 4-(5-nitro-2-furfurylidenamino)-4H-1,2,4-triazole 13185-22-3 T081221 furazonal Russian Drug Index C007802 4-furfurylamino-7-(beta-D-ribofuranosyl)pyrrolo(2,3-d)-pyrimidine 1974 01 01 1983 08 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 7-deaza analog of kinetin riboside; potent anticytokinin; structure 0 FURANS (74-82) *D011741 Pyrimidine Nucleosides Biochem Biophys Res Comm 57(2):412;1974 NLM JSL NLM M0051219 4-furfurylamino-7-(beta-D-ribofuranosyl)pyrrolo(2,3-d)-pyrimidine C0603290 52017-19-3 T081222 4-furfurylamino-7-(beta-D-ribofuranosyl)pyrrolo(2,3-d)-pyrimidine C007803 furobufen 1974 01 01 1989 08 01 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2 *BENZOFURANS (74-812) BUTYRATES (74-82) *D002088 Butyric Acids Can J Physiol Pharmacol 52(3):669;1974 NLM RJM RLS M0051220 furobufen C0060866 gamma-oxo-2-dibenzofuranbutyric acid 38873-55-1 T081223 furobufen C007804 furoxanobenzofuroxan 1974 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CYCLIC N-OXIDES (74-82) *D010069 Oxadiazoles J Med Chem 17(2):203;1974 NLM VSR NLM M0051221 furoxanobenzofuroxan C0603291 5714-12-5 T081224 furoxanobenzofuroxan C007805 furoxanobenzothiadiazole 1974 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 CYCLIC N-OXIDES (74-75) OXADIAZOLES (74-82) *D013830 Thiadiazoles J Med Chem 17(2):203;1974 NLM VSR NLM M0051222 furoxanobenzothiadiazole C0603292 32562-26-8 T081225 furoxanobenzothiadiazole C007811 galactoflavin 1975 01 01 1995 09 13 1995 1996 1997 1998 1999 2000 2001 2002 riboflavin antagonist 3 DULCITOL (75-76) DULCITOL/analogs (75-82) D012256 Riboflavin *Q000031 analogs ; derivatives J Nutrition 105(5):562;1975 J Nutrition 106(1):73;1976 NLM BVL NLM M0051230 galactoflavin C0060956 5401-05-8 T081233 galactoflavin C007814 O-alpha-D-galactopyranosyl-(1-6)-O-alpha-D-galactopyranosyl-(1-1L)-myo-inositol 1974 01 01 1995 06 21 1995 1996 1997 1998 1999 2000 2001 2002 isolated from rapeseed (Brassica campestris) meal; structure 0 *OLIGOSACCHARIDES (74-75) GALACTOSE (74-75) INOSITOL (74-75) *D014312 Trisaccharides Carbohyd Res 29(1):255;1973 NLM MLH NLM M0051233 O-alpha-D-galactopyranosyl-(1-6)-O-alpha-D-galactopyranosyl-(1-1L)-myo-inositol C0603295 D-myo-Inositol, O-alpha-D-galactopyranosyl-(1-6)-O-alpha-D-galactopyranosyl-(1-3)- 51197-08-1 T081236 O-alpha-D-galactopyranosyl-(1-6)-O-alpha-D-galactopyranosyl-(1-1L)-myo-inositol C007815 galactosaminoglycan 1975 01 01 1982 08 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 34 *GALACTOSAMINE (75-79) GALACTOSAMINE/*analogs (75-82) *D011134 Polysaccharides J Bacteriol 120(2):759;1974 NLM CHA NLM M0051234 galactosaminoglycan C0060967 9056-34-2 T081237 galactosaminoglycan C007816 beta-galactoside 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 91 *GLYCOSIDES (74-75) GALACTOSE (74-75) *D005697 Galactosides Proc Nat Acad Sci USA 70(12):3376;1973 NLM NLM M0051235 beta-galactoside C0053436 0 T081238 beta-galactoside C007820 gallein 1975 01 01 1998 01 05 1998 1999 2000 2001 2002 do not confuse with gallin; structure 0 BENZOFURANS (75-82) *D014966 Xanthenes Stain Technol 52(5):261;1977 NLM IDX NLM M0051240 gallein C0061001 3',4',5',6'-tetrahydroxyfluoran 2103-64-2 T081243 gallein C007882 gomphothin 1974 01 01 2001 09 05 2002 extract from herb Gomphocarpus (Asclepiadaceae) 0 PLANT EXTRACTS (74-82) *D006027 Glycosides D029067 Asclepiadaceae Farm Zh 28(3):85;1973 NLM ssb sjn M0051338 gomphothin C0603324 11013-75-5 T081341 gomphothin C007828 gastroluft 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D003287 Contrast Media Radiology 112(1):218;1974 NLM NLM M0051248 gastroluft C0603297 Gastroluft 77462-62-5 T081251 gastroluft C007831 gefarnax 1974 01 01 1990 07 24 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 treatment of gastrointestinal ailments associated with anxiety; contains 50 mg gefarnate; 3 mg diazepam 0 *FATTY ACIDS, UNSATURATED (74-78) *SESQUITERPENES (74-78) *D003975 Diazepam *D005778 Gefarnate D004338 Drug Combinations Minerva Med 64(87):4583;1973 NLM SXR NLM M0051255 gefarnax C0061169 4,8,12-Tetradecatrienoic acid, 5,9,13-trimethyl-, 3,7-dimethyl-2,6-octadienyl ester, (E,E,E)-, mixt. with 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one 77416-72-9 T081258 gefarnax UD 25:100g C007833 gemedine 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D006146 Guanidines Farmakol Toksikol 36(3):273-6;1973 NLM NLM M0051257 gemedine C0603299 1-N-hexamethylenimino)-ethyl-2-guanidine sulfate 2878-51-5 T081260 gemedine C007839 geroton 1974 01 01 1982 07 23 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 polyvitamin-microelement complex; Russian drug 0 *D014815 Vitamins D004338 Drug Combinations Vest Akad Med Nauk SSSR 12:42;1975 Vrach Delo 7(0):56;1973 NLM CHA NLM M0051263 geroton C0061243 12751-14-3 T081266 geroton C007846 gitoxigenin 1969 01 01 1977 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CARDANOLIDES (69-77) *D002298 Cardenolides NLM NLM M0051269 gitoxigenin C0603301 3 beta,14,16 beta-trihydroxy-5 beta-card-20(22)- enolide 545-26-6 T081272 gitoxigenin Merck Index, 8th ed, p. 490 C007850 glucoascorbic acid 1975 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 homolog of ascorbic acid, toxic to mice fed highly purified low fiber diet; structure 1 ASCORBIC ACID/analogs (75-82) KETOSES (75-76) *D006539 Heptoses Am J Clin Nutr 27(12):1395;1974 NLM VSR NLM M0051273 glucoascorbic acid C0162982 3-keto-D-glucoheptonofuranolactone 528-88-1 T081276 glucoascorbic acid C091940 SU protein, equine infectious anemia virus 1995 03 10 2001 07 26 1998 1999 2000 2001 2001A 2002 amino acid sequence given in first source; GenBank M16575 9 *D006023 Glycoproteins *D014759 Viral Envelope Proteins J Virol 1995 Mar;69(3):1493-9 BMB TWD TWD M0242807 SU protein, equine infectious anemia virus C0294107 0 T272812 SU protein, equine infectious anemia virus T272808 EIAV gp90 T272809 env gp90, EIAV T272810 glycoprotein 90, equine infectious anemia virus T272811 surface unit protein, EIAV C032222 3,N(4)-ethenodeoxycytidine 1981 11 27 2000 12 13 1995 1996 1997 1998 1999 2000 2001 2001A 2002 32 D003841 Deoxycytidine *Q000031 analogs ; derivatives Chem Biol Interact 1981;37(1-2):219 MEG CCR CCR M0100691 3,N(4)-ethenodeoxycytidine C0047097 Imidazo(1,2-c)pyrimidin-5(6H)-one, 6-(2-deoxy-beta-D-erythro-pentofuranosyl)- 68498-26-0 T114 Nucleic Acid, Nucleoside, or Nucleotide T130695 3,N(4)-ethenodeoxycytidine T130694 3,N(4)-etheno-2'-deoxycytidine C064068 Thomsen-Friedenreich antigen, cryptic 1990 06 12 2001 07 26 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 detected in rat fetuses with amaranthin 11 *D014312 Trisaccharides D007519 Isoantigens J Histochem Cytochem 1990;38(6):763 RLS CCR CCR M0176642 Thomsen-Friedenreich antigen, cryptic C0084779 0 T206647 Thomsen-Friedenreich antigen, cryptic T206646 cryptic Thomsen-Friedenreich antigen T206643 CTF-antigen T206644 N-acetylneuraminyl-(2-3)-beta-galactosyl (1-3)-N-acetylgalactosamine T206645 NeuAc(alpha)(2-3)-Gal(beta)(1-3)-GalNac(alpha) C007867 glycerol-1,3-diphosphonic acid 1974 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *DIPHOSPHOGLYCERIC ACIDS (76-79) *GLYCERIN (74-76) *ORGANOPHOSPHORUS CPDS (74-76) PHOSPHONIC ACIDS (74-76) *D005994 Glycerophosphates Can J Biochem 51(8):1203;1973 NLM NLM M0051313 glycerol-1,3-diphosphonic acid C0603321 1,2,3-propanetriol 1,3-bis(dihydrogen phosphate) 2075-06-1 T081316 glycerol-1,3-diphosphonic acid C016569 5-methyldeoxycytidine 1978 01 01 2000 12 13 1997 1998 1999 2000 2001 2001A 2002 69 D003841 Deoxycytidine *Q000031 analogs ; derivatives Biokhimiia 43(2):240;1978 NLM CCR CCR M0066662 5-methyldeoxycytidine C0049309 838-07-3 T114 Nucleic Acid, Nucleoside, or Nucleotide T130 Indicator, Reagent, or Diagnostic Aid T096665 5-methyldeoxycytidine T096664 5-methyl-2'-deoxycytidine C007873 glycyl-beta-alanine 1974 01 01 1982 08 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 ALANINE (74-75) GLYCINE (74-75) *D004151 Dipeptides J Biochem (Tokyo) 75(4):825;1974 NLM VSR NLM M0051327 glycyl-beta-alanine C0603323 beta-Alanine, N-glycyl- 7536-21-2 M0051327 M0051326 T081330 glycyl-beta-alanine M0051326 Gly-beta-Ala C0603322 M0051327 M0051326 T081329 Gly-beta-Ala C007876 glyteen 1974 01 01 1994 05 13 1994 1995 1996 1997 1998 1999 2000 2001 2002 tar containing skin drug 3 *D013638 Tars Gann 64(4):323;1973 NLM PML NLM M0051335 glyteen C0061770 Glyteer 39472-33-8 T081338 glyteen C037406 2',3'-dideoxycytidine 5'-triphosphate 1983 03 29 2000 12 13 1995 1996 1997 1998 1999 2000 2001 2001A 2002 inhibits vesicular stomatitis virus RNA synthesis 34 *D003845 Deoxycytosine Nucleotides J Gen Virol l983;64(Pt 3):743 RLS CCR CCR M0113248 2',3'-dideoxycytidine 5'-triphosphate C0045114 Triphosphoric acid, P-((5-(4-amino-2-oxo-1(2H)-pyrimidinyl)tetrahydro-2-furanyl)methyl) ester, (2S-cis)- 66004-77-1 T114 Nucleic Acid, Nucleoside, or Nucleotide T143252 2',3'-dideoxycytidine 5'-triphosphate T143250 2',3'-ddCTP T143251 ddCTP-2',3' C016350 3-deoxyglucosone 1978 01 01 2000 12 13 1998 1999 2000 2001 2001A 2002 RN given refers to (D)-isomer 65 *KETOSES (78-82) D003847 Deoxyglucose *Q000031 analogs ; derivatives J Pharm Soc Jpn 98(2):153;1978 NLM CCR CCR M0066288 3-deoxyglucosone C0047359 4084-27-9 T118 Carbohydrate T096291 3-deoxyglucosone T096289 3-deoxy-D-glucosone T096290 3-deoxyhexosulose C031709 2',3'-dideoxyguanosine 5'-triphosphate 1981 10 02 2000 12 13 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 35 *D003848 Deoxyguanine Nucleotides Proc Natl Acad Sci USA 1981;78(6):3368 RLS CCR CCR M0099442 2',3'-dideoxyguanosine 5'-triphosphate C0045118 Guanosine 5'-(tetrahydrogen triphosphate), 2',3'-dideoxy- 68726-28-3 T114 Nucleic Acid, Nucleoside, or Nucleotide T129446 2',3'-dideoxyguanosine 5'-triphosphate T129445 dideoxy GTP T129444 ddGTP C007885 grandifloric acid 1975 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 diterpene constituent of Aralia cordata Thunb roots; structure 1 CARBOXYLIC ACIDS (75-82) *D004224 Diterpenes Chem Pharm Bull 22(7):1629;1974 NLM VSR NLM M0051341 grandifloric acid C0603326 15 alpha-hydroxy-ent-kaur-16-en-19-oic acid 22338-69-8 T081344 grandifloric acid C007886 granite 1974 01 01 1993 09 01 1994 1995 1996 1997 1998 1999 2000 2001 2002 crystalline rock of quartz, orthoclase, muscovite ; biotite 36 *ALUMINUM SILICATES (74-81) IRON (74-81) *D012822 Silicon Dioxide Am Ind Hyg Assn J 34(7):298;1973 NLM PML TPW M0051343 granite C0061864 0 M0051343 M0051342 T081346 granite M0051342 granodiorite C0120267 M0051343 M0051342 T081345 granodiorite C007887 grosheimin 1974 01 01 1981 11 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 from the aerial parts of V. decurens; structure 0 LACTONES (74-81) *D012717 Sesquiterpenes Pol J Pharmacol Pharm 25(5):477;1973 NLM NBM NLM M0051344 grosheimin C0061908 22489-66-3 T081347 grosheimin C007890 guanidinoacetylglycine 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 GLYCINE (74-75) *D006146 Guanidines D005998 Glycine *Q000031 analogs ; derivatives J Biochem (Tokyo): 75(4):825;1974 NLM NLM M0051346 guanidinoacetylglycine C0603328 Glycine, N-(N-(aminoiminomethyl)glycyl)- 2446-72-2 T081349 guanidinoacetylglycine C026412 washing blue 1980 10 03 2001 07 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 used in treatment of ringworm; contains ultramarine, indigo, Prussian blue, methylene blue, aniline blue with starch, clay, gypsum, chalk and sometimes glycerin; also used for blueing laundry 1 *D004396 Dyes S Afr Med J 1979;56(6):205 RLS jmp jmp M0086768 washing blue C0611100 0 T109 Organic Chemical T130 Indicator, Reagent, or Diagnostic Aid T116771 washing blue Handbook Chem Syn Trade Names, 8th ed, p.114 T116770 blues, laundry C431426 thioplatin 2001 07 26 2001 2002 structure in first source 1 *D009944 Organoplatinum Compounds *D013457 Sulfur Compounds Cancer Chemother Pharmacol 2001 Jun;47(6):461-6 BMB BMB M0394212 thioplatin C0971724 0 T109 Organic Chemical T121 Pharmacologic Substance T455409 thioplatin 2001 07 26 C007902 haloxon 1969 01 01 2001 01 18 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure 17 *COUMARINS (69-79) *D009943 Organophosphorus Compounds *D014468 Umbelliferones Aust Vet J 54(3):154;1978 Berl Muench Tieraerztl Wochenschr 88(1):10;1975 J Am Vet Med Assoc 169(12):1307;1976 J Am Vet Med Assoc 171(5):429;1977 Res Vet Sci 1979;27(1):131 Vet Rec 101(24):477;1977 Vet Rec 99(7):127;1976 NLM CCR CCR M0051371 haloxon C0062110 3-chloro-7-hydroxy-4-methylcoumarin bis(2-chloroethyl)phosphate 321-55-1 M0051371 M0051369 T081374 haloxon Merck Index, 9th ed, p. 600, #4456 T081373 phosphoric acid-bis(2-chloroethyl)(3-chloro-4-methyl-7-coumarin) M0051369 Eustidil C0950245 M0051371 M0051369 T081372 Eustidil C007901 halopropane 1970 01 01 1982 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 *HYDROCARBONS, HALOGENATED (70-82) PROPANE (74-75) D011407 Propane *Q000031 analogs ; derivatives NLM VSR NLM M0051368 halopropane C0603331 3-bromo-1,1,2,2-tetrafluoropropane 679-84-5 T081371 halopropane Merck Index, 9th ed, p. 599, #4453 C112179 sucrase-isomaltase-maltase 1998 05 29 2001 01 19 1998 1999 2000 2001 2001A 2002 an oligo-1,4-1,6-alpha-glucosidase from Bacillus subtilis; involved in maltose and/or isomaltose metabolism; MW 66 kDa; amino acid sequence known 6 *D000520 alpha-Glucosidases *D013394 Sucrase-Isomaltase Complex J Bacteriol 1998 May;180(9):2574-8 BMB WXM WXM M0290187 sucrase-isomaltase-maltase C0674733 EC 3.2.1.- T320192 sucrase-isomaltase-maltase T320191 yvdL gene product T320190 malL gene product T320189 alpha-glucosidase MalL C007910 kamolol 1974 01 01 1982 09 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 terpenoids from Ferula penninervis; structure 0 COUMARINS (74-82) *D012717 Sesquiterpenes Experientia 30(3):224;1974 NLM VSR NLM M0051381 kamolol C0603332 7-((decahydro-7-hydroxy-1,4a,5,6-tetramethyl-1- naphthenyl)methoxy)-2H-1-benzopyran-2-one 58939-88-1 T081384 kamolol C007911 heliogen blue SBL 1974 01 01 1998 01 05 1998 1999 2000 2001 2002 4 *INDOLES (74-77) COPPER (74-82) INDOLES (74-82) *D008665 Metalloporphyrins Tsitologiia 15(9):1103;1973 NLM IDX NLM M0051382 heliogen blue SBL C0062179 copper(dihydrogen phthalocyaninedisulfonato(2)) disodium salt 1330-38-7 T081385 heliogen blue SBL C007914 helveticoside 1974 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *CARDANOLIDES (74-77) STROPHANTHIDIN/*analogs (77-79) *D004071 Digitalis Glycosides *D013328 Strophanthins Farm Zh 31(5):47;1976 Farm Zh 6:52;1978 NLM NLM M0051387 helveticoside C0062195 3-beta-5,14-trihydroxy-19-oxo-5-beta-card-20(22)- enolid-3-digitoxoside /OD/ K-Strophanthidin-3- digitoxoside /OD/ erysimin 630-64-8 T081390 helveticoside Negwer #4675 C007918 hemodes 1974 01 01 1996 01 29 1996 1997 1998 1999 2000 2001 2002 49 SALTS (74-78) *D011205 Povidone D010952 Plasma Substitutes Farmakol Toksikol 41(5):568;1978 Sud Med Ekspert 1979;22(4):53 Vestn Oftalmol 2:57;1973 Z Nevropatol Psychiatr 76(2):278;1976 NLM MLH NLM M0051393 hemodes C0062232 53795-75-8 D000276 Adjuvants, Immunologic D000894 Anti-Inflammatory Agents, Non-Steroidal M0051393 M0051390 M0051393 M0051391 M0051393 M0051392 T081396 hemodes Russian Drug Index p 172 M0051390 gemodes C0119033 M0051393 M0051390 T081393 gemodes M0051391 neocompensan C0132120 M0051393 M0051391 T081394 neocompensan M0051392 neohemodes C0132127 M0051393 M0051392 T081395 neohemodes C007924 heptafluorobutyric anhydride 1974 01 01 1997 08 15 1997 1998 1999 2000 2001 2002 structure 40 *BUTYRATES (74-79) BUTYRATES (74-82) FLUORINE (74-79) *D005466 Fluorocarbons Clin Chem 25(2):218;1979 Infect Immun 9(4):1974 J Chromatogr 123(2):287;1976 J Lipid Res 20(1):78;1979 J. Endocrinol 64:277;1975 NLM MLH NLM M0051397 heptafluorobutyric anhydride C0062550 336-59-4 D007202 Indicators and Reagents T081400 heptafluorobutyric anhydride C007925 heptamethyleneimine 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D001392 Azocines Nature 244(412):176;1973 NLM NLM M0051398 heptamethyleneimine C0062553 1121-92-2 T081401 heptamethyleneimine C007927 1,7-heptanediol 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 1 *D006018 Glycols Nature 247(438):222;1974 NLM NLM M0051399 1,7-heptanediol C0044063 629-30-1 T081402 1,7-heptanediol C007928 hercynine 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *BETAINE (74-75) *HISTIDINE (74-75) D001622 Betaine *Q000031 analogs ; derivatives D006639 Histidine *Q000031 analogs ; derivatives NLM NLM M0051400 hercynine C0603334 (1-carboxy-2-imidazol-4-ylethyl)ammonium hydroxide /OD/ histidine-betaine 534-30-5 T081403 hercynine Merck, 9th ed. #4531 C063367 repressor protein 434 1990 04 13 2001 01 19 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2001B 2002 69 amino acid residues; produced by E coli bacteriophage 434 43 *D012097 Repressor Proteins Science 1990;247(4947):2320 TPW TWD TWD M0174948 repressor protein 434 C0084317 0 T204953 repressor protein 434 T204951 434 repressor protein T204952 434-repressor C007930 hexacarbacholine bromide 1969 01 01 1979 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 *CHOLINE (74-78) CARBAMATES (69-79) CHOLINE/*analogs (78-79) D002217 Carbachol *Q000031 analogs ; derivatives Pharmacol Biochem Behav 8(4):357;1978 Prakt Anaesth 13(5):398;1978 NLM NLM M0051402 hexacarbacholine bromide C0062599 choline bromide hexamethylenedicarbamate /OD/ imbretil /OD/ carbolonium bromide 306-41-2 T081405 hexacarbacholine bromide C012568 terbufos 1976 01 01 2001 01 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 19 *D009946 Organothiophosphorus Compounds Bull Environ Contam Toxicol 1979;23(3):423 J Econ Entomol 69(2):133;1976 NLM CCR CCR M0059678 terbufos C0076112 13071-79-9 M0059678 M0059676 T089681 terbufos T089680 O,O-diethyl S((tert-butylthio)methyl)phosphorodithioate M0059676 Counter C0702263 M0059678 M0059676 T089679 Counter C007933 26,26,26,27,27,27-hexafluorodesmosterol 1974 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *DESMOSTEROL (74-75) STEROIDS, FLUORINATED (74-82) D003897 Desmosterol *Q000031 analogs ; derivatives J Chem Soc (Perkin I):1233;1973 NLM VSR NLM M0051409 26,26,26,27,27,27-hexafluorodesmosterol C0603335 26,26,26,27,27,27-hexafluorocholesta-5,24-dien- 3 beta-ol 0 T081412 26,26,26,27,27,27-hexafluorodesmosterol C007938 2,5-hexanediol 1969 01 01 1980 04 18 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 22 HEXANES (79-80) *D006018 Glycols Ecotoxicol Environ Safety 1979;3(2):204 Proc Royal Soc Med 70(1):37;1977 Rinsho Shinkeigaku 18(11):697;1978 NLM RLS NLM M0051414 2,5-hexanediol C0045573 2935-44-6 T081417 2,5-hexanediol C007945 hippuryl-L-lysine 1975 01 01 1982 09 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 6 *HIPPURATES (75-79) HIPPURATES (79-82) D008239 Lysine *Q000031 analogs ; derivatives Zh Ushn Nos Gorl Bolezn 6:66;1974 NLM VSR NLM M0051426 hippuryl-L-lysine C0062729 N-(N-benzoylglycyl)-L-lysine 740-63-6 T081429 hippuryl-L-lysine C007946 hispidin 1974 01 01 1997 06 04 1997 1998 1999 2000 2001 2002 metabolite of Basidiomycete Polyporus hispidus 2 *PYRANS (74-78) STYRENES (74-82) *D011753 Pyrones D011493 Protein Kinase C Q000037 antagonists ; inhibitors Biochem J 134(4):891;1973 J Pharm Sci 67(4):485;1978 NLM BMB NLM M0051427 hispidin C0062735 6-(3,4-dihydroxystyryl)-4-hydroxy-2-pyrone 555-55-5 T081430 hispidin C007949 hithiol 1975 01 01 1982 09 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 L-cysteine ; glucose mixture used as radiation-protective agent 0 *D003545 Cysteine *D005947 Glucose D004338 Drug Combinations Jpn J Clin Radiol 19(5):339;1974 NLM VSR NLM M0051430 hithiol C0603338 39322-47-9 T081433 hithiol C007951 hodydamycin 1974 01 01 1993 05 03 1994 1995 1996 1997 1998 1999 2000 2001 2002 peptide antibiotic isolated from Streptomyces 0 PEPTIDES (74-93) *D017561 Antibiotics, Peptide J Antibiot (Tokyo) 27(2):133;1974 NLM BXB TPW M0051436 hodydamycin C0603341 51731-71-6 T081439 hodydamycin C018738 acetylspermidine deacetylase 1978 01 01 2001 01 19 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 releases acetic acid from N-1-acetylspermidine, N-8-acetylspermidine and N-1-acetylspermine 14 SPERMIDINE/*analogs (78-81) *D000581 Amidohydrolases Arch Biochem Biophys 199(2):360;1978 NLM WXM WXM M0070554 acetylspermidine deacetylase C0050539 EC 3.5.1.48 T100557 acetylspermidine deacetylase T100555 N(8)-acetylspermidine deacetylase T100554 N(1)-acetylspermidine deacetylase T100556 acylpolyamine amidohydrolase C007958 18-homoestriol 1974 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ESTRIOL (74-75) HOMOSTEROIDS (74-82) D004964 Estriol *Q000031 analogs ; derivatives Drug Metab Disp 1(2):537;1973 NLM VSR NLM M0051449 18-homoestriol C0603346 19882-03-2 T081452 18-homoestriol C007969 hydrazinium 1974 01 01 1982 01 26 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 AMMONIUM COMPOUNDS (74-82) *D006834 Hydrazines Life Sci 13(5):453;1973 NLM NBM NLM M0051467 hydrazinium C0603352 Hydrazinium(1+) 18500-32-8 T081470 hydrazinium C007976 hydrodextran sulfate 1974 01 01 1990 09 12 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 tried therapeutically in experimental arteriosclerosis; structure 0 *DEXTRANS (74-90) SULFONIC ACIDS (74-79) D016264 Dextran Sulfate *Q000031 analogs ; derivatives Folia Pharm Jap 69(6):931;1973 NLM RLS RLS M0051479 hydrodextran sulfate C0603354 0 T081482 hydrodextran sulfate C007977 hydrolapachol 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 inhibits mitochondrial respiratory chain 0 *D009285 Naphthoquinones Biochim Biophys Acta 314(2):154;1973 NLM NLM M0051480 hydrolapachol C0603355 2-hydroxy-3-(3-methylbutyl)-1,4-naphthoquinone 3343-38-2 T081483 hydrolapachol C007995 3-hydroxychol-11-en-24-oic acid 1976 01 01 2001 02 02 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 isolated from culture filtrate of Curvularia species (Deuteromycetes); structure 0 *STEROLS (77-77) HYDROXYSTEROIDS (76-77) *D002770 Cholenes J Chem Soc Perkin I 14(0):1597;1974 J Steroid Biochem 8(1):69;1977 NLM TWD TWD M0051502 3-hydroxychol-11-en-24-oic acid C0046734 0 T081505 3-hydroxychol-11-en-24-oic acid T081504 3 alpha-hydroxy-5 beta-chol-11-en-24-oic acid C007984 11-hydroxyaporphine 1975 01 01 1994 08 02 1995 1996 1997 1998 1999 2000 2001 2002 dopaminergic cpd; RN refers to HBr; structure 1 *D001060 Aporphines J Med Chem 17(10):1090;1974 NLM BMB TPW M0051490 11-hydroxyaporphine C0282884 53055-01-9 T081493 11-hydroxyaporphine C007985 N(5)-hydroxy-L-arginine 1974 01 01 1996 06 19 1996 1997 1998 1999 2000 2001 2002 structure 12 *ARGININE (74-75) D001120 Arginine *Q000031 analogs ; derivatives J Antibiotics 26(5):284;1973 J Antibiotics 28(2):997;1975 NLM PML NLM M0051491 N(5)-hydroxy-L-arginine C0067191 N(5)-(aminoiminomethyl)-N(5)-hydroxy-L-ornithine 42599-90-6 T081494 N(5)-hydroxy-L-arginine C064298 asialogalactochoriongonadotropin 1990 06 28 2001 02 05 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 antagonist of the action of Graves' immunoglobulins in human thyroid membranes 2 *D001212 Asialoglycoproteins *D006063 Chorionic Gonadotropin Horm Metab Res 1990;22(3):196 TPW CCR CCR M0177155 asialogalactochoriongonadotropin C0641301 0 T207160 asialogalactochoriongonadotropin T207158 asialogalacto-HCG T207159 choriongonadotropin, asialogalacto- C007987 5'-hydroxyasperentin 8-O-methyl ether 1974 01 01 1982 10 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 minor metabolite of Aspergillus flavus; structure 0 *PYRANS (74-82) METHYL ETHERS (74-75) *D003374 Coumarins D009183 Mycotoxins J Chem Soc (Perkin I) 22:2704;1973 NLM VSR NLM M0051494 5'-hydroxyasperentin 8-O-methyl ether C0603359 isocoumarin, 3,4-dihydro-6-hydroxy-8-methoxy-3-(5-hydroxy-6- methyltetrahydropyran-2-ylmethyl)- 0 T081497 5'-hydroxyasperentin 8-O-methyl ether C007989 2-(alpha-hydroxybenzyl)imidazo(4,5-c)pyridine 1974 01 01 1982 09 08 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 BENZYL COMPOUNDS (74-75) IMIDAZOLES (74-82) *D011725 Pyridines J Med Chem 16(11):1296;1973 NLM VSR NLM M0051495 2-(alpha-hydroxybenzyl)imidazo(4,5-c)pyridine C0603360 2654-15-1 T081498 2-(alpha-hydroxybenzyl)imidazo(4,5-c)pyridine C007992 11-hydroxycephalotaxine 1974 01 01 1977 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 alkaloid from Cephalotaxus harringtonia var. drupacea; structure 0 *ALKALOIDS (74-77) DIOXOLES (74-77) *D006248 Harringtonines J Org Chem 39(5):676;1974 NLM NLM M0051498 11-hydroxycephalotaxine C0603361 Cephalotaxine, 11-hydroxy-, (11alpha)- 49686-55-7 T081501 11-hydroxycephalotaxine C086457 asialoglycoprotein-polylysine conjugate 1994 04 25 2001 02 05 1995 1996 1997 1998 1999 2000 2001 2001A 2002 4 *D001212 Asialoglycoproteins D011107 Polylysine *Q000031 analogs ; derivatives Am J Med Sci 1994 Feb;307(2):138-43 PML CCR CCR M0229208 asialoglycoprotein-polylysine conjugate C0253144 0 T259213 asialoglycoprotein-polylysine conjugate T259211 AP-PL T259212 AP-poly(L-lysine) conjugate C007998 2-hydroxychromone 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *D002867 Chromones Southern Med J 67(10):1191;1974 NLM NLM M0051508 2-hydroxychromone C0603366 4H-1-Benzopyran-4-one, 2-hydroxy- 22105-09-5 T081511 2-hydroxychromone C103104 asialo-galactosyl-acetylgalactosamine 1997 01 23 2001 02 05 1998 1999 2000 2001 2001A 2002 1 *D001212 Asialoglycoproteins D000116 Acetylgalactosamine *Q000031 analogs ; derivatives J Am Soc Nephrol 1996 Jun;7(6):955-60 PML CCR CCR M0269675 asialo-galactosyl-acetylgalactosamine C0533165 0 T299680 asialo-galactosyl-acetylgalactosamine T299678 asialo-Gal-beta(1-3)-GalNAc T299679 asialo-galactosyl-beta(1-3)-3-N-acetylgalactosamine C008005 hydroxydiiodophenylpyruvic acid 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *PYRUVATES (74-75) IODOBENZENES (74-75) *D010667 Phenylpyruvic Acids Fol Endocrinol Jap 49(9):1167;1973 NLM NLM M0051521 hydroxydiiodophenylpyruvic acid C0603372 Benzenepropanoic acid, 4-hydroxy-3,5-diiodo-alpha-oxo- 780-00-7 T081524 hydroxydiiodophenylpyruvic acid C008010 (8S)-8-hydroxyerythromycin-B 1974 01 01 1978 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ERYTHROMYCIN (74-78) D004917 Erythromycin *Q000031 analogs ; derivatives Helv Chim Acta 56(5):1557;1973 J Antibiot 31(1):55;1978 NLM NLM M0051524 (8S)-8-hydroxyerythromycin-B C0043624 Erythromycin, 12-deoxy-8-hydroxy- 36693-58-0 T081527 (8S)-8-hydroxyerythromycin-B C008011 2-hydroxyestradiol 2,3-methylene ether 1974 01 01 1993 06 22 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ESTRADIOL (74-75) DIOXOLES (74-81) D004958 Estradiol *Q000031 analogs ; derivatives D002393 Estrogens, Catechol Steroids 23(6):869;1974 NLM PML TPW M0051525 2-hydroxyestradiol 2,3-methylene ether C0603374 Estra-1,3,5(10)-trien-17-ol, 2,3-(methylenebis(oxy))-, (17beta)- 53586-37-1 T081528 2-hydroxyestradiol 2,3-methylene ether C008012 2-hydroxyestriol 1974 01 01 1993 06 22 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 9 *ESTRIOL (74-75) HYDROXYSTEROIDS (75-76) D004964 Estriol *Q000031 analogs ; derivatives D002393 Estrogens, Catechol Chem Pharm Bull (Tokyo) 23(7):1613;1975 J Endocrinol 1979;82(1):131 J Steroid Biochem 5(1):1;1974 J Steroid Biochem 6(7):1187;1975 Steroids 28(5):733;1976 NLM PML TPW M0051526 2-hydroxyestriol C0046199 2,16 alpha-dihydroxyestradiol /OD/ estra-1,3,5(10)- triene-2,3,16 alpha,17 beta-tetrol 1232-80-0 T081529 2-hydroxyestriol C008016 2-hydroxyestrone 2,3-methylene ether 1974 01 01 1993 06 22 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *ESTRONE (74-77) DIOXOLES (74-82) *D006894 Hydroxyestrones D002393 Estrogens, Catechol Steroids 23(6):869;1974 NLM PML TPW M0051527 2-hydroxyestrone 2,3-methylene ether C0603375 Estra-1,3,5(10)-trien-17-one, 2,3-(methylenebis(oxy))- 53573-94-7 T081530 2-hydroxyestrone 2,3-methylene ether C008027 N-(2-hydroxyethyl)-2-phenylethyl carbamate 1975 01 01 1983 06 15 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *PHENYLPROPIONATES (76-77) ALCOHOL, ETHYL (75-76) ETHANOLAMINES (76-77) *D002219 Carbamates Br J Pharmacol 51(1):55;1974 West Afr J Pharmacol Drug Res 2(1):77P;1975 NLM JSL NLM M0051549 N-(2-hydroxyethyl)-2-phenylethyl carbamate C0067467 (2-hydroxyethyl)carbamic acid 2-phenylethyl ester 30751-01-0 T081552 N-(2-hydroxyethyl)-2-phenylethyl carbamate C008028 4-hydroxy-2-ethyl-2-phenylglutarimide 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 1 BENZENE DERIVATIVES (74-75) *D010881 Piperidones Drug Metab Dispos 2(2):151;1974 NLM NLM M0051550 4-hydroxy-2-ethyl-2-phenylglutarimide C0048293 3-ethyl-5-hydroxy-3-phenyl-2,6-piperidinedione 50275-60-0 T081553 4-hydroxy-2-ethyl-2-phenylglutarimide C008030 hydroxyethylthiamine 1974 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 3 *THIAMINE (74-76) ALCOHOL, ETHYL (74-76) D010119 Oxythiamine *Q000031 analogs ; derivatives J Am Chem Soc 98(3):808;1976 J Nutr Sci Vitaminol 19:43;1973 NLM RLS NLM M0051552 hydroxyethylthiamine C0063136 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-2,5- bis(2-hydroxyethyl)-4-methylthiazolium chloride 51230-37-6 T081555 hydroxyethylthiamine C009654 verticillins 1974 01 01 2001 02 05 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 3 antibiotics isolated from imperfect fungus Verticillium: verticillin A, verticillin B (mono-3-hydroxymethyl analog of verticillin A), ; verticillin C (differs from verticillin B in that 1 of dioxopiperazine rings has a trisulfide rather than a disulfide bridge; active against gram-positive bacteria ; mycobacteria but not against gram-negative bacteria ; fungi; RN given refers to cpd with unknown MF; structure (verticillins A ; B) 0 DISULFIDES (74-82) D007211 Indoles J Chem Soc Perkin I 17:1819;1973 NLM TWD TWD M0054530 verticillins C0604073 Verticillin 12795-76-5 32164-16-2 (verticillin A) M0054530 M0310863 T084533 verticillins Merck Index, 9th ed, p.1279, #9623 M0310863 verticillin A C0952065 32164-16-2 M0054530 M0310863 T340863 verticillin A 1999 08 18 C008035 N-hydroxy-4'-hydroxy-7,7'-diethyl-trans-N-4-stilbenylacetamide 1974 01 01 1982 09 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 analog of diethylstilbestrol; structure 0 *DIETHYLSTILBESTROL (74-75) ACETAMIDES (74-82) HYDROXYLAMINES (74-75) D004054 Diethylstilbestrol *Q000031 analogs ; derivatives J Med Chem 17(4):386;1974 NLM VSR NLM M0051561 N-hydroxy-4'-hydroxy-7,7'-diethyl-trans-N-4-stilbenylacetamide C0603392 N-(4-(1-ethyl-2-(4-hydroxyphenyl)-1-butenyl)phenyl)-N-hydroxyacetamide 52498-24-5 T081564 N-hydroxy-4'-hydroxy-7,7'-diethyl-trans-N-4-stilbenylacetamide C418053 neutrophil chemotactic protein NCP 2001 01 12 2002 01 25 2001 2001A 2002 2002A CXC chemokine from conditioned medium of stimulated rabbit alveolar macrophages ; shows high homology with human ENA-78 ; granulocyte chemotactic protein-2 ; amino acid sequence in first source 1 *D019743 Chemokines, CXC D009504 Neutrophils Biochemistry 2000 Nov 28;39(47):14549-57 SZM TWD TWD M0376262 neutrophil chemotactic protein NCP C0963159 0 T116 Amino Acid, Peptide, or Protein T129 Immunologic Factor T433010 neutrophil chemotactic protein NCP 2001 01 12 T433012 NCP gene product 2001 01 12 T433011 neutrophil chemotactic gene product 2001 01 12 C008040 5-hydroxy-4-ketohexanoic acid 1975 01 01 1982 09 03 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 HYDROXY ACIDS (75-76) KETO ACIDS (75-82) *D006587 Hexanoic Acids Arch Biol Med Exp Chile 6(Suppl 3):26;1969 NLM VSR NLM M0051568 5-hydroxy-4-ketohexanoic acid C0603396 5-hydroxy-4-oxohexanoic acid 7303-37-9 T081571 5-hydroxy-4-ketohexanoic acid C008042 hydroxylamine-O-sulfonic acid 1975 01 01 1982 09 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 2 SULFONIC ACIDS (75-82) *D006898 Hydroxylamines J Pharm Soc Jpn 94(8):945;1974 NLM VSR NLM M0051569 hydroxylamine-O-sulfonic acid C0063151 2950-43-8 T081572 hydroxylamine-O-sulfonic acid C099604 von Willebrand factor-degrading protease 1996 07 12 2002 01 25 1997 1998 1999 2000 2001 2001A 2002 2002A a large protease from normal human plasma that degrades vWF at the 842Tyr-843Met peptide bond 61 *D008666 Metalloendopeptidases D014841 von Willebrand Factor Blood 1996 May 15;87(10):4223-34 BMB BMB BMB M0261423 von Willebrand factor-degrading protease C0389918 EC 3.4.24.- T291428 von Willebrand factor-degrading protease T291427 vWF-cleaving protease T479360 von Willebrand factor-cleaving protease 2002 01 25 C008052 9-(3-C-hydroxymethyl-alpha-L-threofuranosyl)adenine 1975 01 01 1982 10 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 branched-chain sugar nucleoside; structure 0 *NUCLEOSIDES (75-82) ADENINE/*analogs (75-82) D000241 Adenosine *Q000031 analogs ; derivatives J Med Chem 17(10):1055;1974 NLM VSR NLM M0051590 9-(3-C-hydroxymethyl-alpha-L-threofuranosyl)adenine C0603401 0 T081593 9-(3-C-hydroxymethyl-alpha-L-threofuranosyl)adenine C008053 5-hydroxymethyltubercidin 1974 01 01 1990 09 28 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *RIBONUCLEOSIDES (74-75) PYRIMIDINES (74-75) PYRROLES (74-75) D014372 Tubercidin *Q000031 analogs ; derivatives J Med Chem 16(12):1405;1973 NLM RLS NLM M0051591 5-hydroxymethyltubercidin C0603402 4-amino-7-beta-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-5-methanol 49558-38-5 T081594 5-hydroxymethyltubercidin C008059 (4-hydroxy-3-nitro)benzylated polystyrene 1974 01 01 1982 09 27 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 nitrophenol deriv for peptide synthesis 0 BENZYL COMPOUNDS (74-75) NITROPHENOLS (74-82) *D011137 Polystyrenes Eur J Biochem 42(1):151;1974 NLM VSR NLM M0051599 (4-hydroxy-3-nitro)benzylated polystyrene C0603408 0 T081602 (4-hydroxy-3-nitro)benzylated polystyrene C420662 N4-(mannopyranosyl-(1-6)-(mannopyranosyl)-(1-3)-(2-acetamido-2-deoxy-glucopyranosyl)-(1-2)-(mannopyranosyl)-(1-4)-(2-acetamido-2-deoxy-glucopyranosyl)-(1-4)-(fucopyranosyl)-(1-6)-2-acetamido-2-deoxy-glucopyranosyl)-asparagine 2001 02 27 2002 01 25 2001 2001A 2001B 2002 2002A long chemical ; structure in first source 1 *D009844 Oligosaccharides Carbohydr Res 2000 Sep 22;328(3):263-76 SZM CCR CCR M0379530 N4-(mannopyranosyl-(1-6)-(mannopyranosyl)-(1-3)-(2-acetamido-2-deoxy-glucopyranosyl)-(1-2)-(mannopyranosyl)-(1-4)-(2-acetamido-2-deoxy-glucopyranosyl)-(1-4)-(fucopyranosyl)-(1-6)-2-acetamido-2-deoxy-glucopyranosyl)-asparagine C0964295 0 T118 Carbohydrate M0379530 M0379531 T437331 N4-(mannopyranosyl-(1-6)-(mannopyranosyl)-(1-3)-(2-acetamido-2-deoxy-glucopyranosyl)-(1-2)-(mannopyranosyl)-(1-4)-(2-acetamido-2-deoxy-glucopyranosyl)-(1-4)-(fucopyranosyl)-(1-6)-2-acetamido-2-deoxy-glucopyranosyl)-asparagine 2001 02 27 T437335 Man-Man-A-D-Glu-Man-A-D-Glu-Fuc-A-D-Glu-Asn 2001 02 27 M0379531 N4-(alpha-D-Man-(1-6)-(alpha-D-Man)-(1-3)-(2-acetamido-2-deoxy-beta-D-Glu)-(1-2)-(beta-D-Manl)-(1-4)-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-(1-4)-(alpha-L-Fuc)-(1-6)-2-acetamido-2-deoxy-beta-D-Glul)-L-asparagine C0964296 T118 Carbohydrate M0379530 M0379531 T437332 N4-(alpha-D-Man-(1-6)-(alpha-D-Man)-(1-3)-(2-acetamido-2-deoxy-beta-D-Glu)-(1-2)-(beta-D-Manl)-(1-4)-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-(1-4)-(alpha-L-Fuc)-(1-6)-2-acetamido-2-deoxy-beta-D-Glul)-L-asparagine 2001 02 27 C008065 14-hydroxy-3-oxo-1,4,20,22-bufatetraenolide 1974 01 01 1983 08 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 RN given not in Chemline 8/83; structure 0 HYDROXYSTEROIDS (74-75) KETOSTEROIDS (74-75) *D002018 Bufanolides Planta Med 24(3):201;1973 NLM ACS NLM M0051612 14-hydroxy-3-oxo-1,4,20,22-bufatetraenolide C0603416 41059-91-0 T081615 14-hydroxy-3-oxo-1,4,20,22-bufatetraenolide C008138 3-iodobenzylamine 1974 01 01 2001 02 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 substrate for monoamine oxidase 2 AMINES (74-75) *D007462 Iodobenzenes Anal Biochem 88(2):495;1978 Res Commun Chem Pathol Pharmacol 7(2):419;1974 NLM TWD TWD M0051722 3-iodobenzylamine C0047505 3-iodobenzenemethanamine 696-40-2 T081725 3-iodobenzylamine T081724 meta-iodobenzylamine C008161 ioxynil 1969 01 01 2001 01 11 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 RN given refers to parent cpd; structure 11 *D009570 Nitriles D007462 Iodobenzenes Arch Toxicol 37(3):241;1977 NLM CCR CCR M0051764 ioxynil C0063831 4-hydroxy-3,5-diiodobenzonitrile 1689-83-4 T109 Organic Chemical T131 Hazardous or Poisonous Substance 2961-62-8 (Na salt) M0051764 M0310192 T081767 ioxynil M0310192 ioxynil, sodium salt C0951801 2961-62-8 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0051764 M0310192 T340192 ioxynil, sodium salt 1999 08 18 C081807 F4R protein, orf virus 1993 07 21 2001 02 05 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 homolog to vaccinia H6R gene product; amino acid sequence given in first source 1 *D014764 Viral Proteins Virology 1993 Jul;195(1):175-84 PML WXM WXM M0218139 F4R protein, orf virus C0659653 0 T248144 F4R protein, orf virus T248143 OV F4R C008072 gamma-hydroxyphenylbutazone 1975 01 01 1984 06 28 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 metabolite of phenylbutazone; RN given refers to cpd with unspecified isomeric designation 10 OXYPHENBUTAZONE/*analogs (75-79) D010653 Phenylbutazone *Q000031 analogs ; derivatives Farmaco 31(9):665;1976 J Pharm Sci 63(11):1751;1974 NLM CMG NLM M0051625 gamma-hydroxyphenylbutazone C0061074 4-(3-hydroxybutyl)-1,2-diphenyl-3,5- pyrazolidinedione 568-76-3 36039-31-3 ((+-)-isomer) M0051625 M0051624 M0051625 M0310153 T081628 gamma-hydroxyphenylbutazone M0051624 1,2-diphenyl-3,5-dioxo-4-(3-hydroxybutyl)pyrazolidine C0088115 M0051625 M0051624 T081627 1,2-diphenyl-3,5-dioxo-4-(3-hydroxybutyl)pyrazolidine M0310153 (+-)-isomer of gamma-hydroxyphenylbutazone C0895442 36039-31-3 M0051625 M0310153 T340153 (+-)-isomer of gamma-hydroxyphenylbutazone 1999 08 18 C081824 golgin-95 autoantigen 1993 07 21 2001 02 05 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 from the Golgi complex; encoded by the SY11 protein; reacts with autoantibodies in the sera of patients with autoimmune diseases; amino acid sequence given in first source 4 *D001324 Autoantigens D006056 Golgi Apparatus Q000276 immunology J Exp Med 1993 Jul 1;178(1):49-62 RLS WXM WXM M0218182 golgin-95 autoantigen C0659673 0 T248187 golgin-95 autoantigen T248186 SY11 protein C008074 5-hydroxy-5-phenyllevulinic acid 1974 01 01 1975 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 metabolite of Tubercularia (Moniliales) with analgesic properties; structure 0 *KETO ACIDS (74-75) *VALERATES (74-75) *D007982 Levulinic Acids J Med Chem 17(2):249;1974 NLM NLM M0051628 5-hydroxy-5-phenyllevulinic acid C0603421 delta-hydroxy-gamma-oxobenzenepentanoic acid 51366-15-5 T081631 5-hydroxy-5-phenyllevulinic acid C420663 heptakis(2-O-methyl-3,6-di-O-sulfo)cyclomaltoheptaose 2001 02 27 2002 01 25 2001 2002 2002A structure in first source 1 *D009844 Oligosaccharides Carbohydr Res 2000 Sep 22;328(3):277-85 SZM CCR CCR M0379533 heptakis(2-O-methyl-3,6-di-O-sulfo)cyclomaltoheptaose C0964298 0 T118 Carbohydrate T130 Indicator, Reagent, or Diagnostic Aid T437336 heptakis(2-O-methyl-3,6-di-O-sulfo)cyclomaltoheptaose 2001 02 27 T437337 H-(M-di-S)CMH 2001 02 27 C445019 cytochrome P-450A3 2002 01 25 2002 has been sequenced 2 *D003577 Cytochrome P-450 Enzyme System *D006899 Mixed Function Oxygenases J Biochem (Tokyo) 2001 Oct;130(4):569-74 BMB BMB M0412309 cytochrome P-450A3 EC 1.14.- T127 Vitamin T479361 cytochrome P-450A3 2002 01 25 T479362 CYP102A3 gene product 2002 01 25 T479363 cytochrome P-450 A3 2002 01 25 T479364 yrhJ gene product 2002 01 25 C081826 Dpbx protein 1993 07 22 2001 02 05 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 homeobox gene product found in Drosophila; related to the human proto-oncogene pbx1; highly homologous to the pbx proteins; located on the X chromosome at 14A; high levels observed in the anterior portion of the ventral nerve cord; amino acid sequence given in first source; GenBank Z18864 1 *D004268 DNA-Binding Proteins Mech Dev 1993 May;41(2-3):155-61 RLS WXM WXM M0218186 Dpbx protein C0659675 0 T248191 Dpbx protein T248190 Dpbx gene product C008094 hymenoflorin 1974 01 01 1998 05 20 1998 1999 2000 2001 2002 antileukemic agent isolated from Hymenoxygrandiflora; structure 0 LACTONES (74-75) *D012717 Sesquiterpenes J Org Chem 39(14):2013;1974 NLM BQV NLM M0051661 hymenoflorin C0603428 51292-63-8 T081664 hymenoflorin C008104 IgO 1974 01 01 1982 09 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 postulated that hemolytic anemia is caused by IgO antibodies 1 *D007136 Immunoglobulins Munch Med Wochenschr 115(39):1650;1973 NLM VSR NLM M0051672 IgO C0063354 0 T081675 IgO C008111 incanine 1974 01 01 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 alkaloid contained in toxic plant Trichodesma incanum 0 *D000470 Alkaloids Sud Med Ekspert 16(3):37;1973 NLM NLM M0051685 incanine C0603436 14,19-dihydro-12-hydroxy-19-methylcrotalanan-11,15- dione 480-77-3 T081688 incanine C008119 indolyl-3-acetic acid N-methyl-1-phenyl-2,3-dimethyl- 1974 01 01 1986 12 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *INDOLEACETIC ACID (74-75) AMIDES (74-75) PYRAZOLES (74-82) D007210 Indoleacetic Acids *Q000031 analogs ; derivatives Acta Pol Pharm 31(2):151;1974 NLM PEH NLM M0051695 indolyl-3-acetic acid N-methyl-1-phenyl-2,3-dimethyl- C0603439 1H-Indole-3-acetamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-N-methyl- 53995-77-0 T081698 indolyl-3-acetic acid N-methyl-1-phenyl-2,3-dimethyl- C008120 indolyl-3-acetic acid (1-phenyl-2,3-dimethyl-5-oxo-4- pyrazolyl) amide 1974 01 01 1982 09 29 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 structure 0 *INDOLEACETIC ACID (74-75) AMIDES (74-75) PYRAZOLES (74-82) D007210 Indoleacetic Acids *Q000031 analogs ; derivatives Acta Pol Pharm 31(2):151;1974 NLM VSR NLM M0051696 indolyl-3-acetic acid (1-phenyl-2,3-dimethyl-5-oxo-4- pyrazolyl) amide C0603440 1H-Indole-3-acetamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)- 53995-76-9 T081699 indolyl-3-acetic acid (1-phenyl-2,3-dimethyl-5-oxo-4- pyrazolyl) amide C008121 indolylheptylamine 1974 01 01 1990 09 20 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 0 *D007211 Indoles D015306 Biogenic Monoamines Sov J Dev Biol 2(1):1;1971 NLM TBT NLM M0051697 indolylheptylamine C0603441 1H-indole-3-heptanamine 29852-47-9 T081700 indolylheptylamine C030911 2-nitro-7-methoxynaphtho(2-1b)furan 1981 08 14 2001 02 02 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 structure given in first source 27 *D009581 Nitrofurans Mutat Res 1981;88(4):355 MEG CCR CCR M0097502 2-nitro-7-methoxynaphtho(2-1b)furan C0093504 Naphtho(2,1-b)furan, 7-methoxy-2-nitro- 75965-74-1 T109 Organic Chemical T131 Hazardous or Poisonous Substance D000970 Antineoplastic Agents D002273 Carcinogens D009153 Mutagens M0097502 M0097505 T127506 2-nitro-7-methoxynaphtho(2-1b)furan T127507 7-methoxy-2-nitronaphtho(2,1-b)furan M0097505 R 7000 C0072927 T109 Organic Chemical T131 Hazardous or Poisonous Substance M0097502 M0097505 T127509 R 7000 T127508 R-7000 C032572 furapyrimidone 1982 01 06 2001 01 12 1989 1990 1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2001A 2002 16 *D009581 Nitrofurans Chung-Kuo Yao Li Hseuh Pao 1980;1(1):60 MEG CCR CCR M0101596 furapyrimidone C0060854 75888-03-8 T109 Organic Chemical T121 Pharmacologic Substance T131600 furapyrimidone